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Featured San Francisco Luxury Hotels

See all 815 properties in San Francisco

Estimated price for 1 night/2 adults

Palace Hotel, a Luxury Collection Hotel, San Francisco
Palace Hotel, a Luxury Collection Hotel, San Francisco
5.0 out of 5.0 2 New Montgomery St, San Francisco, CA
Free Cancellation
4.5/5 (3467 reviews)
C$237/ night for 2 guests

Great pool and gym facilities, great room, very clean

Reviewed on 11 Jun. 2019
Fairmont San Francisco
Fairmont San Francisco
5.0 out of 5.0 950 Mason Street Atop Nob Hill, San Francisco, CA
Free Cancellation
4.5/5 (4302 reviews)
C$272/ night for 2 guests

Rooms are large, good food options, free happy hour, beautiful building and good location compared to other options.

Reviewed on 23 Jun. 2019
Huntington Hotel
Huntington Hotel
4.5 out of 5.0 1075 California St, San Francisco, CA
Free Cancellation
4.6/5 (1791 reviews)
C$258/ night for 2 guests

Perfect location with a real upscale feel to the property. A doorman who acknowledges your coming and going, super friendly and helpful front desk staff. Rooms are HUGE for a hotel! We got great city views with corner room offering tons of natural light. A definite recommend for anyone looking to ...

Reviewed on 22 Jun. 2019
Omni San Francisco Hotel
Omni San Francisco Hotel
4.5 out of 5.0 500 California St, San Francisco, CA
Free Cancellation
4.7/5 (1964 reviews)
C$244/ night for 2 guests

very clean and the staff were helpful and friendly

Reviewed on 18 Jun. 2019
Loews Regency San Francisco
Loews Regency San Francisco
5.0 out of 5.0 222 Sansome St, San Francisco, CA
Free Cancellation
4.7/5 (644 reviews)
C$439/ night for 2 guests

The service and hospitality was fabulous Everything was so so so so so so so good . Everything was just on the side like I like ;) Ea & evry 1 of the staff was TBE The boys sold the loads quick so we got to enjoy brunch! Yours truly , on the side

Reviewed on 17 Jun. 2019
The St. Regis San Francisco
The St. Regis San Francisco
5.0 out of 5.0 125 3rd St, San Francisco, CA
Free Cancellation
4.7/5 (434 reviews)
C$427/ night for 2 guests

Great room and superb swimming pool. Excellent gym and very good location

Reviewed on 7 May 2019
InterContinental San Francisco
InterContinental San Francisco
4.5 out of 5.0 888 Howard Street, San Francisco, CA
Free Cancellation
4.4/5 (2025 reviews)
C$221/ night for 2 guests

Well placed for visiting San Francisco, with friendly and helpful advice for first time visitors

Reviewed on 23 Jun. 2019
Taj Campton Place
Taj Campton Place
5.0 out of 5.0 340 Stockton St, San Francisco, CA
Free Cancellation
4.5/5 (1091 reviews)
C$263/ night for 2 guests

Truly excellent service. The hotel is great and location is perfect. The one annoying thing is they charge an extra $30/day for various services (bottled water in room, wifi, coffee in lobby, etc). Make sure you consider that when you choose by price.

Reviewed on 22 Jun. 2019
Four Seasons Hotel San Francisco
Four Seasons Hotel San Francisco
5.0 out of 5.0 757 Market St, San Francisco, CA
Free Cancellation
4.6/5 (630 reviews)
C$522/ night for 2 guests

Staff was grate and the location was easy to get around town.

Reviewed on 20 May 2019
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Luxury Hotels: Our travellers loved these

Estimated price for 1 night/2 adults

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When you'll take your luxury hotel with a side of thrilling city attractions, you've found your niche in San Francisco. As one of the most intriguing destinations for travelers who want to check out city life, San Francisco is a great place to make memories. Brilliant experiences, delicious eats, and chances to take terrific photos: these are just a few of the reasons to take a trip to San Francisco. You'll enjoy the most popular performances, treat yourself to the city's best food, and marvel at the most popular attractions in the region. Naturally, you'll book a room at a luxury hotel! Extravagant experiences are right up your alley, so book your luxury hotel in San Francisco on Expedia.com today, and your relaxing escape is off to a good start.

5-Star Vacations in San Francisco

If you doubt that San Francisco is full of marvelous things to do, consider that 864,816 people are happy to call it home. No matter what brings you to San Francisco, the destination always delivers. San Francisco is full of dreamy hotels on top of appealing attractions, so it's no surprise that travelers come back. Book early to get the best room!

A luxury retreat is the perfect opportunity to indulge in art, culture, and spa treatments. When you book your travel on Expedia.com, you can enjoy it all. Thanks to our spectacular room rates, you'll still have enough money for the most fun and free-spirited things to do. After an eventful day of exploration, your luxury suite awaits. Before you crawl into bed, order a glass of wine to your room and revel in your successful day. The luxury rooms and suites in San Francisco will put you into a state of serenity before you know it.

Luxury Hotels in San Francisco

It's that time; you're ready to get swept away in The Baghdad by the Bay, and Expedia.com is here to save the day. Browse the wealth of reviews on dozens of hotels and then book your ideal room in minutes. Luxury accommodations offer amenities like elegant suites and concierge services. Some of the city's luxe accommodations even feature upscale penthouses, while others offer rejuvenating spa treatments. Use our mobile booking app to find and book an incredible 5-star hotel in San Francisco, and before you know it you'll be getting pampered in paradise!