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Featured San Francisco Luxury Hotels

See all 509 Hotels in San Francisco
Fairmont San Francisco

Fairmont San Francisco

950 Mason Street Atop Nob Hill, San Francisco
5.0 out of 5.0
4.4 out of 5 (2,052 reviews)
Atop Beautiful Nob HillWhile we had an interior view room, there are so many great views from everywhere you go around near the hotel. The breakfasts were fresh and well prepared. Our room was well appointed, spotlessly clean, with up to date bathroom appointments. We would definitely stay here again.
  21 Sep 2017

C$344

C$344
Palace Hotel, a Luxury Collection Hotel, San Francisco

Palace Hotel, a Luxury Collection Hotel, San Francisco

2 New Montgomery St, San Francisco
5.0 out of 5.0
4.5 out of 5 (1,535 reviews)
Wouldn't hesitate to recommend this wonderful hotel. Staff are excellent and willing to go the extra mile for guests, room was spotlessly clean and the location was convenient for shopping as well as accessing public transport services. The hotel food is very expensive but there are plenty of other ...
  20 Sep 2017

C$289

C$289
Omni San Francisco Hotel

Omni San Francisco Hotel

500 California St, San Francisco
4.5 out of 5.0
4.7 out of 5 (1,643 reviews)
Excellent hotel close to all tourist attractions This hotel is really fabulous. ALL the staff are there to help you to have a good holiday. On arrival at the hotel the bellboy helped with our luggage and the receptionist quickly checked us in and we went straight to our excellent room. The cleaners were excellent. The restaurant and bar were a ...
  21 Sep 2017

C$323

C$323
The Scarlet Huntington Hotel

The Scarlet Huntington Hotel

1075 California St, San Francisco
4.5 out of 5.0
4.6 out of 5 (583 reviews)
Oh, that hill back to the hotel!!We loved the Scarlett Huntington. We upgraded to a deluxe room and it was worth it. Lots of space and a huuuge bed. The hotel is in nob hill which is far enough out of union Square to keep away from the noise but it's still close enough to walk in. Just beware the massive hill when coming back ...
  19 Sep 2017

C$368

C$368
Loews Regency San Francisco

Loews Regency San Francisco

222 Sansome St, San Francisco
5.0 out of 5.0
4.6 out of 5 (207 reviews)
Friendly staff, clean facilities, and more than helpful to tell us things we can do.
  21 Sep 2017

C$429

C$429
The Ritz-Carlton, San Francisco

The Ritz-Carlton, San Francisco

600 Stockton St, San Francisco
5.0 out of 5.0
4.5 out of 5 (404 reviews)
AMAZING HOTEL Amazing hotel, great stuff, delicious food and drinks ! Overall great experiences !!!!
  7 Sep 2017

C$474

C$474
InterContinental San Francisco

InterContinental San Francisco

888 Howard Street, San Francisco
4.5 out of 5.0
4.4 out of 5 (903 reviews)
Very clean and nice. The bar is also great Good hotel with friendly staff. Close to everything.
  19 Sep 2017

C$231

C$231
The St. Regis San Francisco

The St. Regis San Francisco

125 3rd St, San Francisco
5.0 out of 5.0
4.7 out of 5 (105 reviews)
First Class Customer ServiceThe St. Regis knows how to deliver a first class experience. Staff know how to make things happen to make your stay very comfortable. Had my daughter bike over to the hotel and Louie made sure her bike was safe and taken care of. Enjoyed the lobby bar and dined st the Grill for breakfast. If you ...
  13 Sep 2017

C$412

C$412
Taj Campton Place

Taj Campton Place

340 Stockton St, San Francisco
5.0 out of 5.0
4.6 out of 5 (429 reviews)
Wonderful stay in the TajHotel is in a perfect location in San Francisco, the room was very clean and comfortable and spacious. Great breakfast
  7 Sep 2017

C$369

C$369
Map

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When you'll take your luxury hotel with a side of thrilling city attractions, you've found your niche in San Francisco. As one of the most intriguing destinations for travelers who want to check out city life, San Francisco is a great place to make memories. Brilliant experiences, delicious eats, and chances to take terrific photos: these are just a few of the reasons to take a trip to San Francisco. You'll enjoy the most popular performances, treat yourself to the city's best food, and marvel at the most popular attractions in the region. Naturally, you'll book a room at a luxury hotel! Extravagant experiences are right up your alley, so book your luxury hotel in San Francisco on Expedia.com today, and your relaxing escape is off to a good start.

5-Star Vacations in San Francisco

If you doubt that San Francisco is full of marvelous things to do, consider that 864,816 people are happy to call it home. No matter what brings you to San Francisco, the destination always delivers. San Francisco is full of dreamy hotels on top of appealing attractions, so it's no surprise that travelers come back. Book early to get the best room!

A luxury retreat is the perfect opportunity to indulge in art, culture, and spa treatments. When you book your travel on Expedia.com, you can enjoy it all. Thanks to our spectacular room rates, you'll still have enough money for the most fun and free-spirited things to do. After an eventful day of exploration, your luxury suite awaits. Before you crawl into bed, order a glass of wine to your room and revel in your successful day. The luxury rooms and suites in San Francisco will put you into a state of serenity before you know it.

Luxury Hotels in San Francisco

It's that time; you're ready to get swept away in The Baghdad by the Bay, and Expedia.com is here to save the day. Browse the wealth of reviews on dozens of hotels and then book your ideal room in minutes. Luxury accommodations offer amenities like elegant suites and concierge services. Some of the city's luxe accommodations even feature upscale penthouses, while others offer rejuvenating spa treatments. Use our mobile booking app to find and book an incredible 5-star hotel in San Francisco, and before you know it you'll be getting pampered in paradise!