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Featured San Francisco Luxury Hotels

See all 525 Hotels in San Francisco
Fairmont San Francisco

Fairmont San Francisco

950 Mason Street Atop Nob Hill, San Francisco
5.0 out of 5.0
4.5 out of 5 (4,916 reviews)
In a city without a ton of options...Not the worst but also not worth paying an exorbitant price for. Old hotel. Old restaurant. Friendly staff. Rooms really do need an iodate, especially the bathrooms.
  17 Nov 2017

C$252

C$252
Palace Hotel, a Luxury Collection Hotel, San Francisco

Palace Hotel, a Luxury Collection Hotel, San Francisco

2 New Montgomery St, San Francisco
5.0 out of 5.0
4.5 out of 5 (3,569 reviews)
Elegant and beautiful hotel Palace hotel is full of charm and has a beautiful garden court for dining. It may not be as extravagant as some of the other hotels but it is magnificent in its own way!
  21 Nov 2017

C$211

C$211
Omni San Francisco Hotel

Omni San Francisco Hotel

500 California St, San Francisco
4.5 out of 5.0
4.7 out of 5 (3,990 reviews)
Awesome experience. Professional and friendly staff.
  19 Nov 2017

C$216

C$216
The Scarlet Huntington Hotel

The Scarlet Huntington Hotel

1075 California St, San Francisco
4.5 out of 5.0
4.6 out of 5 (1,569 reviews)
Great location Hotel restaurant was wonderfulVery nice boutique hotel across from Grace Cathedral, a beautiful site atnight
  20 Nov 2017

C$234

C$234
Loews Regency San Francisco

Loews Regency San Francisco

222 Sansome St, San Francisco
5.0 out of 5.0
4.6 out of 5 (371 reviews)
Great location in the financial districtWonderful views from the rooms, all on high floors.
  17 Nov 2017

C$343

C$343
The Ritz-Carlton, San Francisco

The Ritz-Carlton, San Francisco

600 Stockton St, San Francisco
5.0 out of 5.0
4.5 out of 5 (767 reviews)
Amazing serviceThe hotel was a perfect blend of contemporary and classic. The staff were incredible, attentive, and friendly. They really made it feel like home away from home. Can’t wait for my next stay!
  16 Nov 2017

C$424

C$424
Argonaut Hotel - a Noble House Hotel

Argonaut Hotel - a Noble House Hotel

495 Jefferson St, San Francisco
4.5 out of 5.0
4.6 out of 5 (5,584 reviews)
Great location at Fisherman's wharf Traveled here for business. First time at this hotel and the staff and service was wonderful!!!
  18 Nov 2017

C$206

C$206
InterContinental San Francisco

InterContinental San Francisco

888 Howard Street, San Francisco
4.5 out of 5.0
4.5 out of 5 (2,838 reviews)
Great location...overall niceI enjoyed my stay so much that i didn't want to leave. Fitness center was reasonable. Swimming pool and jacuzzi was nice. The location of the hotel was beyond ideal. The hotel staff made me feel like a celebrity. If i ever return to San Francisco, I'll definitely make my reservations at the ...
  29 Oct 2017

C$181

C$181
The St. Regis San Francisco

The St. Regis San Francisco

125 3rd St, San Francisco
5.0 out of 5.0
4.7 out of 5 (290 reviews)
Deluxe hotel next to SFMOMAExcellent. Staff and facilities all excellent. I was at the hotel for one week and found all aspects of the hotel superb and a pleasure to stay in.
  6 Nov 2017

C$451

C$451
Taj Campton Place

Taj Campton Place

340 Stockton St, San Francisco
5.0 out of 5.0
4.6 out of 5 (902 reviews)
Great hotel, amazing staffHad a great 7 day stay at Taj Campton hotel, best hotel we have stayed at in our US holiday. The staff were amazing, extremely polite and pleasant. The restaurant in the hotel was fantastic, I would stay here again and recommend it highly.
  23 Oct 2017

C$381

C$381
Map

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When you'll take your luxury hotel with a side of thrilling city attractions, you've found your niche in San Francisco. As one of the most intriguing destinations for travelers who want to check out city life, San Francisco is a great place to make memories. Brilliant experiences, delicious eats, and chances to take terrific photos: these are just a few of the reasons to take a trip to San Francisco. You'll enjoy the most popular performances, treat yourself to the city's best food, and marvel at the most popular attractions in the region. Naturally, you'll book a room at a luxury hotel! Extravagant experiences are right up your alley, so book your luxury hotel in San Francisco on Expedia.com today, and your relaxing escape is off to a good start.

5-Star Vacations in San Francisco

If you doubt that San Francisco is full of marvelous things to do, consider that 864,816 people are happy to call it home. No matter what brings you to San Francisco, the destination always delivers. San Francisco is full of dreamy hotels on top of appealing attractions, so it's no surprise that travelers come back. Book early to get the best room!

A luxury retreat is the perfect opportunity to indulge in art, culture, and spa treatments. When you book your travel on Expedia.com, you can enjoy it all. Thanks to our spectacular room rates, you'll still have enough money for the most fun and free-spirited things to do. After an eventful day of exploration, your luxury suite awaits. Before you crawl into bed, order a glass of wine to your room and revel in your successful day. The luxury rooms and suites in San Francisco will put you into a state of serenity before you know it.

Luxury Hotels in San Francisco

It's that time; you're ready to get swept away in The Baghdad by the Bay, and Expedia.com is here to save the day. Browse the wealth of reviews on dozens of hotels and then book your ideal room in minutes. Luxury accommodations offer amenities like elegant suites and concierge services. Some of the city's luxe accommodations even feature upscale penthouses, while others offer rejuvenating spa treatments. Use our mobile booking app to find and book an incredible 5-star hotel in San Francisco, and before you know it you'll be getting pampered in paradise!