Title: Book the Best San Antonio LUXURY Hotels - Upscale Hotels in San Antonio, FL | Expedia.ca [Hotels in San Antonio](https://expedia.ca/San-Antonio-Hotels.d553248634999009134.Travel-Guide-Hotels)[Vacation Rentals in San Antonio](https://expedia.ca/San-Antonio-Vacation-Rentals.d553248634999009134.Travel-Guide-VacationRentals)[Flights to San Antonio](https://expedia.ca/Cheap-Flights-To-San-Antonio.d553248634999009134.Travel-Guide-Flights)[San Antonio Car Rentals](https://expedia.ca/Car-Rentals-In-San-Antonio.d553248634999009134.Car-Rental-Guide)[San Antonio Vacation Packages](https://expedia.ca/San-Antonio.d553248634999009134.Destination-Travel-Guides) ![Default HTG hotel image](https://a.travel-assets.com/travel-assets-manager/bex-affinities/luxury.jpeg?impolicy=fcrop&w=1200&h=500&q=medium) # Find luxury hotels in San Antonio, FL - ![](https://a.travel-assets.com/travel-assets-manager/pictogram-bex/light__calendar_shield.svg) ### Change your mind Book hotels with free cancellation - ![](https://a.travel-assets.com/travel-assets-manager/pictogram-bex/light__deals.svg) ### Treat yourself Sign in to save 10% or more on thousands of hotels [Sign in](https://www.expedia.ca/login) - ![](https://a.travel-assets.com/travel-assets-manager/pictogram-bex/light__bed.svg) ### Be picky Search almost a million properties worldwide ## Check availability on San Antonio Luxury Hotels Tonight [Nov 4 - Nov 5](https://www.expedia.ca/Hotel-Search?regionId=553248634999009134&startDate=2025-11-04&endDate=2025-11-05&adults=2&propertyStyle=LUXURY&rfrr=TG.LP.CheckPrices.Hotel&openPlayBack=true&travelerType=luxury_property) Tomorrow [Nov 5 - Nov 6](https://www.expedia.ca/Hotel-Search?regionId=553248634999009134&startDate=2025-11-05&endDate=2025-11-06&adults=2&propertyStyle=LUXURY&rfrr=TG.LP.CheckPrices.Hotel&openPlayBack=true&travelerType=luxury_property) This weekend [Nov 7 - Nov 9](https://www.expedia.ca/Hotel-Search?regionId=553248634999009134&startDate=2025-11-07&endDate=2025-11-09&adults=2&propertyStyle=LUXURY&rfrr=TG.LP.CheckPrices.Hotel&openPlayBack=true&travelerType=luxury_property) Next weekend [Nov 14 - Nov 16](https://www.expedia.ca/Hotel-Search?regionId=553248634999009134&startDate=2025-11-14&endDate=2025-11-16&adults=2&propertyStyle=LUXURY&rfrr=TG.LP.CheckPrices.Hotel&openPlayBack=true&travelerType=luxury_property) ## Top San Antonio Luxury Hotels ## Top San Antonio Hotel Reviews ![Hilton Garden Inn Tampa North Busch Gardens](//images.trvl-media.com/lodging/1000000/470000/463200/463141/8750897d_y.jpg) ### Hilton Garden Inn Tampa North Busch Gardens 10/10 Excellent "Excellent breakfast!" [](https://expedia.ca/Tampa-Hotels-Hilton-Garden-Inn-Tampa-North-Busch-Gardens.h463141.Hotel-Information) ![Holiday Inn Express Hotel & Suites New Tampa I-75 by IHG](//images.trvl-media.com/lodging/1000000/920000/915000/914906/c9dda0fe_y.jpg) ### Holiday Inn Express Hotel & Suites New Tampa I-75 by IHG 10/10 Excellent "The rooms were clean. The staff were friendly. There were restaurants and other shops nearby." [](https://expedia.ca/Tampa-Hotels-Holiday-Inn-Express-Hotel-Suites-New-Tampa-I-75.h914906.Hotel-Information) ![Sleep Inn near Busch Gardens/USF](//images.trvl-media.com/lodging/1000000/90000/85100/85025/ab979cd6_y.jpg) ### Sleep Inn near Busch Gardens/USF 10/10 Excellent "Breakfast was cold and flavorless" [](https://expedia.ca/Tampa-Hotels-Sleep-Inn-Near-Busch-GardensUSF.h85025.Hotel-Information) ![Quality Inn Zephyrhills - Dade City](//images.trvl-media.com/lodging/1000000/980000/977400/977325/a0e87607_y.jpg) ### Quality Inn Zephyrhills - Dade City 10/10 Excellent "Clean room" [](https://expedia.ca/Tampa-Hotels-Quality-Inn-Zephyrhills-Dade-City.h977325.Hotel-Information) ![Hampton Inn & Suites Tampa-North](//images.trvl-media.com/lodging/1000000/70000/60700/60625/d1f06e42_y.jpg) ### Hampton Inn & Suites Tampa-North 10/10 Excellent "Family had a great stay!" [](https://expedia.ca/Tampa-Hotels-Hampton-Inn-Suites-Tampa-North.h60625.Hotel-Information) ![Microtel Inn & Suites by Wyndham Brooksville](//images.trvl-media.com/lodging/3000000/2180000/2173600/2173502/ff59b893_y.jpg) ### Microtel Inn & Suites by Wyndham Brooksville 10/10 Excellent "No frills hotel. Overall the staff were very friendly, room was clean. Has a bar, pool and cardio gym. Parking was free and location is easy in/off interstate for travelers just needing a rest. " [](https://expedia.ca/Port-Richey-Hotels-Microtel-Inn-Suites-By-Wyndham-Brooksville.h2173502.Hotel-Information) ## Frequently asked questions ### Which area of San Antonio is best to stay in for luxury hotels? > For luxury hotels in San Antonio, Florida, the best area to stay is generally around the town centre or slightly to its west, particularly near the more established, well-maintained estates. > > > > The town centre itself is quite small, centred around Main Street and State Road 52. You'll find a few local shops and eateries here, giving it a quaint, community feel. The area is characterised by its historic architecture and a slower pace of life, reflecting its rural Floridian charm. > > > > Couples looking for a refined and quiet escape will find this area appealing. Luxury accommodations here often provide a more private, boutique experience, with high-end amenities like gourmet dining options, extensive spa services, and well-maintained grounds. You're also well-placed for a relaxed day out, perhaps exploring the local area or enjoying the natural surroundings. > > > > For those seeking high-end fitness and leisure facilities, some luxury properties slightly west of the town centre offer access to things like championship golf courses, tennis courts, and state-of-the-art fitness centres with personal training available. ### How much does a luxury hotel in San Antonio cost? > Luxury hotel prices in San Antonio vary, but you can find a great deal on Expedia. To find the best prices on luxury stays, be flexible with your dates—typically, off-peak and mid-week stays are cheaper. Sort your search results by "Price: low to high" to see our lowest rates. ### What luxury activities and experiences are there in San Antonio? > The best area to stay in San Antonio, Florida, for luxury activities and experiences is generally around the Lake Jovita Golf & Country Club development. > > > > This area is located just east of the main San Antonio village centre and is characterised by its expansive, well-maintained grounds, private residences, and the central golf course. It's a more secluded and upscale part of the region, offering a tranquil setting away from busier areas. > > > > Couples looking for a refined getaway will find this area particularly appealing. The focus here is on relaxation and high-end leisure. You'll find opportunities for golf on championship courses, as well as access to facilities that often include excellent dining options and well-appointed clubhouses. Some accommodations in this area might offer private balconies with views of the golf course or the surrounding natural landscapes, superb for a quiet evening. > > > > For those interested in maintaining their wellness routine, some of the private accommodations or nearby facilities within this development may offer access to amenities like high-end fitness equipment or swimming pools. ### How can I save on a luxury hotel in San Antonio with Expedia? > There are plenty of ways to save on a luxury hotel in San Antonio. Unlock our lowest prices by joining [One Key™](https://www.expedia.ca/welcome-one-key), Expedia's travel rewards program. It's free and easy to sign up, and you can access member perks too. Typically, booking in advance will help you save on your luxury hotel booking. If you're feeling spontaneous, be sure to check for last-minute deals. ### Is it cheaper to book a luxury San Antonio hotel and flights as a package? > Booking a hotel and flight package on Expedia can be cheaper than booking flights and hotels separately. Bundling can lead to significant savings, especially for international travel or when booking well in advance. However, savings vary depending on factors like destination, travel dates, and availability, so it's wise to compare options. With access to over 300,000 hotels worldwide, Expedia makes it easy to build the perfect travel package. ### Can I cancel my luxury hotel reservation on Expedia? > Many Expedia hotel reservations are refundable, provided that you cancel before the hotel's cancellation deadline. This is often within 24-48 hours of your scheduled arrival. Be sure to check your booking confirmation for the exact cancellation policy. 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[Beach Hotel Hotels in Wesley Chapel South](https://www.expedia.ca/Wesley-Chapel-South-Tampa-Hotels-Beach-Hotel.0-n553248635975849470-0-tBeachHotel.Travel-Guide-Filter-Hotels) - [Cheap Hotels in Wesley Chapel South](https://www.expedia.ca/Wesley-Chapel-South-Tampa-Hotels-Cheap-Hotels.0-n553248635975849470-0-tCheapHotels.Travel-Guide-Filter-Hotels) - [Hotels & Resorts for Couples in Wesley Chapel South](https://www.expedia.ca/Wesley-Chapel-South-Tampa-Hotels-Couples-Resorts-Hotels.0-n553248635975849470-0-tCouplesResortsHotels.Travel-Guide-Filter-Hotels) - [Golf Hotels in Wesley Chapel South](https://www.expedia.ca/Wesley-Chapel-South-Tampa-Hotels-Golf-Hotel.0-n553248635975849470-0-tGolfHotel.Travel-Guide-Filter-Hotels) - [Hotels with Wifi in Wesley Chapel South](https://www.expedia.ca/Wesley-Chapel-South-Tampa-Hotels-Hotel-With-Wifi.0-n553248635975849470-0-tHotelwithwifi.Travel-Guide-Filter-Hotels) - [Hotels with Kitchenettes in Wesley Chapel South](https://www.expedia.ca/Wesley-Chapel-South-Tampa-Hotels-Hotels-With-Kitchenettes.0-n553248635975849470-0-tHotelswithKitchenettes.Travel-Guide-Filter-Hotels) - 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