Hotel Markus Sittikus is very well-located near important Salzburg sights such as Mirabell. Not far across the river are the remaining key locations, including the Fortress.
Initially, the hotel seemed very pricey, and indeed, compared to others we stayed in, even in Munich, it was far and away the most expensive. However, it was reasonable within Salzburg and the surrounding area. It's just an expensive city to visit.
We enjoyed the public spaces (living room with coffee machine, bar, garden) and the friendly staff. Breakfast was bountiful, but very expensive and far too much for our appetites, so we ate there only one morning. Plenty of other options near by. Parking added to the total cost.