Title: Book the Best Saint Jo LUXURY Hotels - Upscale Hotels in Saint Jo, TX | Expedia.ca [Hotels in Saint Jo](https://expedia.ca/Saint-Jo-Hotels.d3000459225.Travel-Guide-Hotels)[Vacation Rentals in Saint Jo](https://expedia.ca/Saint-Jo-Vacation-Rentals.d3000459225.Travel-Guide-VacationRentals)[Saint Jo Car Rentals](https://expedia.ca/Car-Rentals-In-Saint-Jo.d3000459225.Car-Rental-Guide)[Saint Jo Vacation Packages](https://expedia.ca/Saint-Jo.d3000459225.Destination-Travel-Guides) ![Default HTG hotel image](https://a.travel-assets.com/travel-assets-manager/bex-affinities/luxury.jpeg?impolicy=fcrop&w=1200&h=500&q=medium) # Find luxury hotels in Saint Jo, TX - ![](https://a.travel-assets.com/travel-assets-manager/pictogram-bex/light__calendar_shield.svg) ### Change your mind Book hotels with free cancellation - ![](https://a.travel-assets.com/travel-assets-manager/pictogram-bex/light__deals.svg) ### Treat yourself Sign in to save 10% or more on thousands of hotels [Sign in](https://www.expedia.ca/login) - ![](https://a.travel-assets.com/travel-assets-manager/pictogram-bex/light__bed.svg) ### Be picky Search almost a million properties worldwide ## Check availability on Saint Jo Luxury Hotels Tonight [Nov 6 - Nov 7](https://www.expedia.ca/Hotel-Search?regionId=3000459225&startDate=2025-11-06&endDate=2025-11-07&adults=2&propertyStyle=LUXURY&rfrr=TG.LP.CheckPrices.Hotel&openPlayBack=true&travelerType=luxury_property) Tomorrow [Nov 7 - Nov 8](https://www.expedia.ca/Hotel-Search?regionId=3000459225&startDate=2025-11-07&endDate=2025-11-08&adults=2&propertyStyle=LUXURY&rfrr=TG.LP.CheckPrices.Hotel&openPlayBack=true&travelerType=luxury_property) This weekend [Nov 7 - Nov 9](https://www.expedia.ca/Hotel-Search?regionId=3000459225&startDate=2025-11-07&endDate=2025-11-09&adults=2&propertyStyle=LUXURY&rfrr=TG.LP.CheckPrices.Hotel&openPlayBack=true&travelerType=luxury_property) Next weekend [Nov 14 - Nov 16](https://www.expedia.ca/Hotel-Search?regionId=3000459225&startDate=2025-11-14&endDate=2025-11-16&adults=2&propertyStyle=LUXURY&rfrr=TG.LP.CheckPrices.Hotel&openPlayBack=true&travelerType=luxury_property) ## Top Saint Jo Luxury Hotels ## Top Saint Jo Hotel Reviews ![La Quinta Inn & Suites by Wyndham Gainesville](//images.trvl-media.com/lodging/2000000/1760000/1753000/1752905/aa02f5b8_y.jpg) ### La Quinta Inn & Suites by Wyndham Gainesville 10/10 Excellent "Yes" [](https://expedia.ca/Gainesville-Hotels-La-Quinta-Inn-Suites-By-Wyndham-Gainesville.h1752905.Hotel-Information) ![Best Western Red River Inn & Suites](//images.trvl-media.com/lodging/3000000/2230000/2227700/2227691/93ace492_y.jpg) ### Best Western Red River Inn & Suites 10/10 Excellent "Excellent Customer Service.👌 " [](https://expedia.ca/Ardmore-Hotels-Best-Western-Red-River-Inn-Suites.h2227691.Hotel-Information) ![Red River Inn And Suites](//images.trvl-media.com/lodging/6000000/5800000/5797900/5797801/28674795_y.jpg) ### Red River Inn And Suites 10/10 Excellent "Nice room! Very clean! Nice breakfast & always kept clean." [](https://expedia.ca/Ardmore-Hotels-Red-River-Inn-And-Suites.h5797801.Hotel-Information) ![Quality Inn Gainesville](//images.trvl-media.com/lodging/1000000/20000/14100/14044/d4fc726e_y.jpg) ### Quality Inn Gainesville 10/10 Excellent "Good for one night " [](https://expedia.ca/Gainesville-Hotels-Quality-Inn-Gainesville.h14044.Hotel-Information) ![Super 8 by Wyndham Gainesville TX](//images.trvl-media.com/lodging/1000000/930000/922300/922204/701c761a_y.jpg) ### Super 8 by Wyndham Gainesville TX 10/10 Excellent "Yes" [](https://expedia.ca/Gainesville-Hotels-Super-8-By-Wyndham-Gainesville-TX.h922204.Hotel-Information) ## Frequently asked questions ### Are you searching for a great accommodation for your luxury trip to Saint Jo? > Amenities are an important consideration when you plan a vacation, so we make it easy to find what you want to make your stay relaxing and comfortable. If you want a posh hotel that has a spa, an indoor pool, or luxury bedding, Expedia can assist you in finding the best luxury hotel experience that Saint Jo offers. Saint Jo has some interesting things to see and do including Red River and St Jo Downtown Park, so you might want to take in the local sights during your visit. ### When can I expect good weather in Saint Jo? > Planning for the weather is a good way to make your trip to Saint Jo relaxing and enjoyable, especially when you're splurging. The hottest months are usually August and July with an average temp of 82°F, while the coldest months are January and February with an average of 48°F. Average annual precipitation for Saint Jo is 41 inches. ### What's there to see and do in Saint Jo? > Take in some sights and attractions while you're in Saint Jo by visiting Red River, St Jo Downtown Park, and Arche Vineyards & Winery. 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