Title: Domus 21 Luxury Suites (Guesthouse) - Latest Reviews, Deals & Photos 2026 - Expedia.ca [See all properties](http://www.expedia.ca/Hotel-Search?regionId=&selected=75710309&adults=2&children=&sort=RECOMMENDED&useRewards=false&semdtl=&userIntent=&vip=false) # Domus 21 Luxury Suites Travelers find a genuine Roman home base at Domus 21 Luxury Suites, where express check-in and coworking spaces complement easy access to Campo de' Fiori ## Photo gallery for Domus 21 Luxury Suites ![Exterior - Domus 21 Luxury Suites (Rome)](https://images.trvl-media.com/lodging/76000000/75720000/75710400/75710309/b8b9f5a4.jpg?impolicy=resizecrop&rw=598&ra=fit) ![Grand Room - Domus 21 Luxury Suites (Rome)](https://images.trvl-media.com/lodging/76000000/75720000/75710400/75710309/63b5c704.jpg?impolicy=resizecrop&rw=297&ra=fit) ![Interior - Domus 21 Luxury Suites (Rome)](https://images.trvl-media.com/lodging/76000000/75720000/75710400/75710309/b46f9b9b.jpg?impolicy=resizecrop&rw=297&ra=fit) ![Exterior - Domus 21 Luxury Suites (Rome)](https://images.trvl-media.com/lodging/76000000/75720000/75710400/75710309/0cc1d42b.jpg?impolicy=resizecrop&rw=297&ra=fit) ![Hallway - Domus 21 Luxury Suites (Rome)](https://images.trvl-media.com/lodging/76000000/75720000/75710400/75710309/7f181e6a.jpg?impolicy=resizecrop&rw=297&ra=fit) - Overview - Rooms - Location - Policies Located in central Rome, Domus 21 Luxury Suites welcomes families with practical comforts. The property offers pet-sitting services, coworking areas with reliable in-room WiFi, and express check-in/out. Guests consistently praise the attentive staff. ## Reviews 9.8 Exceptional ## Popular amenities - Pet friendly - Free WiFi - Air conditioning - Laundry - Housekeeping ### VIP AccessSee the benefits you'll enjoy with VIP Access > Get more when you're a member > > - Save 15% or more on select VIP Access properties when you reach Silver tier or above > - Experience top-rated quality and exceptional service > - Get an in-stay perk at select properties, plus free room upgrades, early check-in, and late check-out when available > > [Learn more](https://www.expedia.ca/lp/b/vipaccess) ## Room options ### Check availability for these dates Tonight [Jan. 27 - Jan. 28](https://www.expedia.ca/Hotel-Search?startDate=2026-01-27&endDate=2026-01-28&selected=75710309&PinnedHotelID=75710309&HadPinnedHotel=true®ionId=-1&adults=2) [](https://www.expedia.ca/Hotel-Search?startDate=2026-01-27&endDate=2026-01-28&selected=75710309&PinnedHotelID=75710309&HadPinnedHotel=true®ionId=-1&adults=2) Tomorrow [Jan. 28 - Jan. 29](https://www.expedia.ca/Hotel-Search?startDate=2026-01-28&endDate=2026-01-29&selected=75710309&PinnedHotelID=75710309&HadPinnedHotel=true®ionId=-1&adults=2) [](https://www.expedia.ca/Hotel-Search?startDate=2026-01-28&endDate=2026-01-29&selected=75710309&PinnedHotelID=75710309&HadPinnedHotel=true®ionId=-1&adults=2) This weekend [Jan. 30 - Feb. 1](https://www.expedia.ca/Hotel-Search?startDate=2026-01-30&endDate=2026-02-01&selected=75710309&PinnedHotelID=75710309&HadPinnedHotel=true®ionId=-1&adults=2) [](https://www.expedia.ca/Hotel-Search?startDate=2026-01-30&endDate=2026-02-01&selected=75710309&PinnedHotelID=75710309&HadPinnedHotel=true®ionId=-1&adults=2) Next weekend [Feb. 6 - Feb. 8](https://www.expedia.ca/Hotel-Search?startDate=2026-02-06&endDate=2026-02-08&selected=75710309&PinnedHotelID=75710309&HadPinnedHotel=true®ionId=-1&adults=2) [](https://www.expedia.ca/Hotel-Search?startDate=2026-02-06&endDate=2026-02-08&selected=75710309&PinnedHotelID=75710309&HadPinnedHotel=true®ionId=-1&adults=2) All rooms 1 bed 2 beds Showing 4 of 4 rooms ### View all photos for Superior Room, 1 Queen Bed, Courtyard View ![Superior Room, 1 Queen Bed, Courtyard View](https://images.trvl-media.com/lodging/76000000/75720000/75710400/75710309/09e7d21d.jpg?impolicy=fcrop&w=1200&h=800&quality=medium) ### Superior Room, 1 Queen Bed, Courtyard View 10.0 Exceptional 2 reviews ### Highlights Separate sitting area Soundproofed Individually furnished Individually decorated Air conditioning Connecting rooms available Free cribs/infant beds Minibar (some free items) - 215 sq ft - Sleeps 3 - 1 Queen Bed ### View all photos for Deluxe Room, City View ![Deluxe Room, City View | View from room](https://images.trvl-media.com/lodging/76000000/75720000/75710400/75710309/857e0600.jpg?impolicy=fcrop&w=1200&h=800&quality=medium) ### Deluxe Room, City View 9.6 Exceptional 4 reviews ### Highlights Soundproofed Air conditioning Connecting rooms available Free cribs/infant beds Minibar (some free items) Smart TV Hypo-allergenic bedding Pillow menu - 258 sq ft - Sleeps 2 - 1 King Bed OR 2 Twin Beds - City view ### View all photos for Junior Suite ![Junior Suite](https://images.trvl-media.com/lodging/76000000/75720000/75710400/75710309/73403aac.jpg?impolicy=fcrop&w=1200&h=800&quality=medium) ### Junior Suite 10.0 Exceptional 3 reviews ### Highlights Soundproofed Air conditioning Connecting rooms available Free cribs/infant beds Minibar (some free items) Smart TV Hypo-allergenic bedding Pillow menu - 431 sq ft - Sleeps 4 - 1 King Bed - City view ### View all photos for Grand Room ![Grand Room](https://images.trvl-media.com/lodging/76000000/75720000/75710400/75710309/45845097.jpg?impolicy=fcrop&w=1200&h=800&quality=medium) ### Grand Room ### Highlights Soundproofed Air conditioning Connecting rooms available Free cribs/infant beds Minibar (some free items) Smart TV Hypo-allergenic bedding Pillow menu - 366 sq ft - Sleeps 3 - 1 King Bed - City view ## You may also like Ad ![Terrace/patio](https://images.trvl-media.com/lodging/4000000/3220000/3213900/3213890/a4410a45.jpg?impolicy=fcrop&w=357&h=201&p=1&q=medium) #### Coronari Palace Rome City Centre - Breakfast included - Free WiFi - Air conditioning - Laundry 9.0 Wonderful 1,001 reviews CA $153 CA $188 total includes taxes & fees Jan 29 - Jan 30 [](https://www.expedia.ca/Rome-Hotels-Coronari-Palace.h3213890.Hotel-Information?chkin=2026-1-29&chkout=2026-1-30&rm1=a2®ionId=179899&destination=Rome (and vicinity)&destType=MARKET&latLong=41.903755,12.479556&searchId=1d095484-1b6d-45f5-96fe-f6971fe99eac&top_cur=CAD) Ad ![Free daily buffet breakfast](https://images.trvl-media.com/lodging/75000000/74550000/74544500/74544467/dd4c9d31.jpg?impolicy=fcrop&w=357&h=201&p=1&q=medium) #### Hotel L'Orologio Roma Rome City Centre - Breakfast included - Pet friendly - Free WiFi - Air conditioning 9.6 Exceptional 441 reviews CA $268 CA $320 total includes taxes & fees Jan 28 - Jan 29 [](https://www.expedia.ca/Rome-Hotels-Hotel-LOrologio.h74544467.Hotel-Information?chkin=2026-1-28&chkout=2026-1-29&rm1=a2®ionId=179899&destination=Rome (and vicinity)&destType=MARKET&latLong=41.903755,12.479556&searchId=1d095484-1b6d-45f5-96fe-f6971fe99eac&top_cur=CAD) Ad ![Premium bedding, minibar, in-room safe, desk](https://images.trvl-media.com/lodging/11000000/10420000/10411300/10411204/080fa795.jpg?impolicy=fcrop&w=357&h=201&p=1&q=medium) #### Mama's Home Rome Rome City Centre - Free WiFi - Air conditioning - Housekeeping - Soundproof rooms 9.4 Exceptional 496 reviews CA $192 CA $227 total includes taxes & fees Jan 28 - Jan 29 [](https://www.expedia.ca/Rome-Hotels-Mamas-Home-Rome.h10411204.Hotel-Information?chkin=2026-1-28&chkout=2026-1-29&rm1=a2®ionId=179899&destination=Rome (and vicinity)&destType=MARKET&latLong=41.903755,12.479556&searchId=1d095484-1b6d-45f5-96fe-f6971fe99eac&top_cur=CAD) Ad ![Piazza del Popolo - Exclusive Room | View from room](https://images.trvl-media.com/lodging/110000000/109340000/109334600/109334517/ad798357.jpg?impolicy=fcrop&w=357&h=201&p=1&q=medium) #### Tritone Luxury Suites Piazza del Popolo Rome City Centre - Free WiFi - Air conditioning - Housekeeping - Soundproof rooms 9.4 Exceptional 38 reviews CA $226 CA $331 total includes taxes & fees Jan 28 - Jan 29 [](https://www.expedia.ca/Rome-Hotels-Tritone-Luxury-Suites-Piazza-Del-Popolo.h109334517.Hotel-Information?chkin=2026-1-28&chkout=2026-1-29&rm1=a2®ionId=179899&destination=Rome (and vicinity)&destType=MARKET&latLong=41.903755,12.479556&searchId=1d095484-1b6d-45f5-96fe-f6971fe99eac&top_cur=CAD) Ad ![Presidential Suite](https://images.trvl-media.com/lodging/24000000/23020000/23010900/23010868/0048778e.jpg?impolicy=fcrop&w=357&h=201&p=1&q=medium) #### Martius Private Suites Hotel Rome City Centre - Breakfast included - Free WiFi - Air conditioning - Laundry 9.6 Exceptional 379 reviews CA $545 CA $624 total includes taxes & fees Jan 28 - Jan 29 [](https://www.expedia.ca/Rome-Hotels-Martius-Private-Suites.h23010868.Hotel-Information?chkin=2026-1-28&chkout=2026-1-29&rm1=a2®ionId=179899&destination=Rome (and vicinity)&destType=MARKET&latLong=41.903755,12.479556&searchId=1d095484-1b6d-45f5-96fe-f6971fe99eac&top_cur=CAD) Ad ![City view from property](https://a.travel-assets.com/media/meso_cm/PAPI/Images/lodging/75000000/74060000/74055900/74055827/932fd053_b.jpg?impolicy=fcrop&w=357&h=201&p=1&q=medium) #### Trastevere Roma | UNA Esperienze Rome City Centre - 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Breakfast included - Free WiFi - Restaurant - Air conditioning 9.8 Exceptional 379 reviews CA $729 CA $834 total includes taxes & fees Jan 31 - Feb 1 [](https://www.expedia.ca/Rome-Hotels-Singer-Palace-Hotel.h21117476.Hotel-Information?chkin=2026-1-31&chkout=2026-2-1&rm1=a2®ionId=179899&destination=Rome (and vicinity)&destType=MARKET&latLong=41.903755,12.479556&searchId=1d095484-1b6d-45f5-96fe-f6971fe99eac&top_cur=CAD) Ad ![Restaurant](https://a.travel-assets.com/media/meso_cm/PAPI/Images/lodging/16000000/15340000/15336100/15336024/9719a6ce_b.jpg?impolicy=fcrop&w=357&h=201&p=1&q=medium) #### The Tribune, part of JdV by Hyatt Rome City Centre - Free WiFi - Air conditioning - Breakfast available - Bar 9.2 Wonderful 1,001 reviews CA $271 CA $322 total includes taxes & fees Feb 3 - Feb 4 [](https://www.expedia.ca/Rome-Hotels-The-Tribune.h15336024.Hotel-Information?chkin=2026-2-3&chkout=2026-2-4&rm1=a2®ionId=179899&destination=Rome (and vicinity)&destType=MARKET&latLong=41.903755,12.479556&searchId=1d095484-1b6d-45f5-96fe-f6971fe99eac&top_cur=CAD) Ad ![Superior Double Room, Terrace](https://images.trvl-media.com/lodging/3000000/2230000/2222500/2222425/f97ca989.jpg?impolicy=fcrop&w=357&h=201&p=1&q=medium) #### UNA Hotels Decò Roma Rome City Centre - Pet friendly - Free WiFi - Restaurant - Air conditioning 9.2 Wonderful 1,528 reviews CA $170 CA $212 total includes taxes & fees Feb 1 - Feb 2 [](https://www.expedia.ca/Rome-Hotels-UNAHOTELS-Deco-Roma.h2222425.Hotel-Information?chkin=2026-2-1&chkout=2026-2-2&rm1=a2®ionId=179899&destination=Rome (and vicinity)&destType=MARKET&latLong=41.903755,12.479556&searchId=1d095484-1b6d-45f5-96fe-f6971fe99eac&top_cur=CAD) ![Mod logo](https://a.travel-assets.com/pricing-claim/sparkle_dark.svg) Sign in to view eligible discounts and perks. More rewards for more adventures! [Sign in](https://www.expedia.ca/login?ckoflag=0&uurl=e3id%3Dredr%26rurl%3D%2FRome-Hotels-Domus-21-Luxury-Suites.h75710309.Hotel-Information)[Sign up, it's free](https://www.expedia.ca/signup?enable_registration=true&uurl=e3id%3Dredr%26rurl%3D%2FRome-Hotels-Domus-21-Luxury-Suites.h75710309.Hotel-Information) ## About the area Located in Rome City Centre neighborhood, Domus 21 Luxury Suites is connected to a rail/subway station. Vatican Museums and Castel Sant'Angelo are cultural highlights, and travelers looking to shop may want to visit Via del Corso and Via Veneto. Looking to enjoy an event or a game? See what's going on at Foro Italico or Stadio Olimpico. Be sure not to miss outdoor adventures like skydiving, mountain biking, and mountain climbing, or hop on a segway rental nearby and take a self-guided tour around the aera. [Visit our Rome travel guide](https://www.expedia.ca/Rome.dx179899) [View more Guest houses in Rome](https://www.expedia.ca/Rome-Guest-Houses.d179899-aaGuestHouses.Travel-Guide-Accommodation) ![Map](https://maps.googleapis.com/maps/api/staticmap?&size=660x330&map_id=3b266eb50d2997c6&zoom=13&markers=icon:https%3A%2F%2Fa.travel-assets.com%2Ftravel-assets-manager%2Feg-maps%2Fproperty.png%7C41.89608%2C12.47826&channel=expedia-HotelInformation&maptype=roadmap&scale=1&key=AIzaSyCYjQus5kCufOpSj932jFoR_AJiL9yiwOw&signature=oHfhGwCYPa8_zk5bktEbTlAzi_o=) Corso Vittorio Emanuele II 21, Rome, RM, 00186 ### What's nearby - ![Area Sacra di Largo Argentina which includes a ruin and heritage elements](https://images.trvl-media.com/place/6146991/7ca8edbc-394b-4fc4-b042-f04c3d1b05e3.jpg?impolicy=resizecrop&rw=115.61&rh=65.03&ra=fit&q=high) Largo di Torre Argentina 2 min walk \- 0.2 km - Teatro Faiano 1 min walk \- 0.0 km - Piazza della Minerva 2 min walk \- 0.2 km - Santa Maria Sopra Minerva 2 min walk \- 0.2 km - Chiesa del Gesù 2 min walk \- 0.2 km ### Getting around - Venezia Tram Stop 4 min walk - Rome San Pietro Station 5 min drive - Fiumicino - Leonardo da Vinci Intl. Airport (FCO) 40 min drive ### Restaurants - Alice Pizza Largo Argentina 1 min walk - Shari Vari 5 min walk - Te Amo 5 min walk - PASTAEAT la pastapoke 1 min walk - Appetito Cafe 5 min walk ## About this property ### Domus 21 Luxury Suites Luxury family-friendly guesthouse near Pantheon A short walk from Campo de' Fiori and Piazza Navona, Domus 21 Luxury Suites provides dry cleaning/laundry services and more. Guests can connect to free in-room WiFi. Other perks include: - A roundtrip airport shuttle (surcharge), an electric car charging station, and express check-out - Express check-in, tour/ticket assistance, and pet-sitting services - Bicycle tour information, pet grooming services, and bicycle parking - Guest reviews speak highly of the helpful staff Room features All guestrooms at Domus 21 Luxury Suites have comforts such as premium bedding and pillow menus, in addition to thoughtful touches like laptop-compatible safes and air conditioning. Extra amenities include: - Highchairs, children's books, and art supplies - Reusable coffee/tea filters, recycling, and LED light bulbs - Rainfall showers, designer toiletries, and bidets - Composting, eco-friendly cleaning products, and childcare services ## Similar properties ![Junior Suite, 1 King Bed, City View](https://images.trvl-media.com/lodging/8000000/7480000/7472600/7472512/7c8a6d9b.jpg?impolicy=fcrop&w=469&h=201&p=1&q=medium) ### Torre Argentina Relais Rome City Centre - Free WiFi - Air conditioning - Breakfast available - Parking available 9.4 Exceptional 539 reviews CA $148 CA $182 total includes taxes & fees Jan 29 - Jan 30 [](https://www.expedia.ca/Hotel-Search?startDate=2026-01-29&endDate=2026-01-30&selected=7472512&PinnedHotelID=7472512&HadPinnedHotel=true®ionId=-1&adults=2) ![View from property](https://images.trvl-media.com/lodging/19000000/18790000/18788900/18788851/53b8784c.jpg?impolicy=fcrop&w=469&h=201&p=1&q=medium) ### Rhea Silvia Luxury Navona Rome City Centre - 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Free WiFi - Air conditioning - Laundry - Housekeeping 9.8 Exceptional 26 reviews CA $169 CA $209 total includes taxes & fees Jan 28 - Jan 29 [](https://www.expedia.ca/Hotel-Search?startDate=2026-01-28&endDate=2026-01-29&selected=109844601&PinnedHotelID=109844601&HadPinnedHotel=true®ionId=-1&adults=2) ![Junior Suite (3 Persons)](https://images.trvl-media.com/lodging/29000000/28870000/28866900/28866804/d3c8a3af.jpg?impolicy=fcrop&w=469&h=201&p=1&q=medium) ### Little Queen Pantheon Residence Rome City Centre - Free WiFi - Air conditioning - Breakfast available - Housekeeping 9.4 Exceptional 229 reviews CA $164 CA $203 total includes taxes & fees Jan 29 - Jan 30 [](https://www.expedia.ca/Hotel-Search?startDate=2026-01-29&endDate=2026-01-30&selected=28866804&PinnedHotelID=28866804&HadPinnedHotel=true®ionId=-1&adults=2) ![Property entrance](https://images.trvl-media.com/lodging/13000000/12360000/12353000/12352908/cb9771c4.jpg?impolicy=fcrop&w=469&h=201&p=1&q=medium) ### Jb Relais Luxury Rome City Centre - Free WiFi - Air conditioning - Laundry - Housekeeping 9.4 Exceptional 171 reviews [](https://www.expedia.ca/Hotel-Search?startDate=2026-02-10&endDate=2026-02-11&selected=12352908&PinnedHotelID=12352908&HadPinnedHotel=true®ionId=-1&adults=2) [Compare similar properties](/Hotel-Search?startDate=2026-02-10&endDate=2026-02-11&selected=75710309&PinnedHotelID=75710309&HadPinnedHotel=true®ionId=-1&adults=2&comparePropertyIds=75710309,7472512,18788851,17159014,36126867) ## Property amenities ### Internet - Available in all rooms: Free WiFi and wired internet - In-room WiFi speed: 500+ Mbps (good for 6+ people or 10+ devices) - Available in some public areas: Free WiFi ### Parking and transportation - Electric car charging station on site - Offsite parking within 1 mile (EUR 24 per day); discounts available - Street parking available - 24-hour roundtrip airport shuttle at scheduled times and on request for a surcharge ### Food and drink - Couples/private dining - Private picnics ### Things to do - Bicycle tours - Books - Helicopter/airplane tours - Private wine tours - Wine tours - Winery release events ### Family friendly - Art supplies - Baby toys - Children's books - Children's games - Children's toys - High chair - In-room babysitting (surcharge) - In-room crib - Laundry facilities - Soundproofed rooms ### Conveniences - Free newspapers in lobby - Guidebooks - Laundry facilities - Limited-hour front desk - Luggage storage ### Guest services - Change of towels on request - Concierge services - Dry cleaning/laundry service - Housekeeping (daily) - Proposal/romance packages - Tour and ticket assistance - Turndown service ### Business services - Coworking space ### Accessibility - If you have requests for specific accessibility needs, please contact the property using the information on the reservation confirmation received after booking. - Accessible airport shuttle - Elevator - Well-lit path to entrance ### More - At least 10% of profits reinvested in community and sustainability - At least 80% lighting from LEDs - Comprehensive food waste policy - Comprehensive recycling policy - Double-glazed windows - Humane treatment of captive wild animals - Local artist showcase - Local culture and ecosystem education - Locally-owned and organized tours and activities - Smoking not allowed ## Room amenities ### Bedroom - Blackout drapes - Down comforter - Egyptian cotton sheets - Free crib - Hypo-allergenic bedding - Pillow menu - Pillowtop mattress ### Bathroom - Bathrobes - Bidet - Designer toiletries - Hair dryer - Rainfall showerhead - Shampoo - Shower - Slippers - Soap - Toilet paper - Toothbrush and toothpaste (on request) - Towels provided ### Food and drink - Champagne service - Coffee/tea maker - Electric kettle - Espresso maker - Free bottled water - Free minibar (limited items) - Restaurant dining guides ### More - Air conditioning - Cleaning products are eco-friendly - Composting - Connecting rooms available - Eco-friendly toiletries - Electrical adapters - Energy-saving switches in guestrooms - Free daily newspapers - Iron/ironing board on request - Laptop-compatible safe - LED lighting - Mobile key entry - Printer - Recycling - Reusable coffee/tea filters - Soundproofed rooms - Water-efficient showers - Water-efficient toilets ## Policies ### Check-in Check-in start time: 2:00 PM; Check-in end time: 11:30 AM Contactless check-in available Express check-in available Minimum check-in age: 15 ### Check-out Check-out before 11:30 AM Contactless check-out available Express check-out available ### Special check-in instructions This property offers transfers from the airport (surcharges may apply); guests must contact the property with arrival details before travel, using the contact information on the booking confirmation The front desk is open daily from 9:00 AM - 5:00 PM Guests planning to arrive outside of normal check-in hours must contact the property in advance for check-in instructions and key retrieval information; front desk staffed during limited hours To make arrangements for check-in please contact the property at least 24 hours before arrival using the information on the booking confirmation If you are planning to arrive after 2:00 PM please contact the property in advance using the information on the booking confirmation Information provided by the property may be translated using automated translation tools ### Access methods Front desk (limited hours), key retrieval ### Pets Pets stay free Service animals are welcome, and are exempt from fees Welcoming dogs and cats only 4 total (up to 22 lbs per pet) Pets cannot be left unattended Food and water bowls, pet-sitting services, litter boxes, and pet grooming services are available ### Children and extra beds Children are welcome Rollaway/extra beds are not available Free cribs are available on request at the property ### Property payment types ## Important information ### Fees You'll be asked to pay the following charges at the property. Fees may include applicable taxes: - A tax is imposed by the city: EUR 5.00 per person, per night, up to 10 nights. This tax does not apply to children under 10 years of age. We have included all charges provided to us by the property. ### Optional extras - Airport shuttle fee: EUR 70 per vehicle (one-way, maximum occupancy 2) - Airport shuttle fee per child: EUR 70 (one-way), (from 10 to 18 years old) - Nearby parking fee: EUR 24 per day (3281 ft away) The above list may not be comprehensive. Fees and deposits may not include tax and are subject to change. ### You need to know Extra-person charges may apply and vary depending on property policy Government-issued photo identification and a credit card, debit card, or cash deposit may be required at check-in for incidental charges Special requests are subject to availability upon check-in and may incur additional charges; special requests cannot be guaranteed This property accepts credit cards, debit cards, and cash Cashless transactions are available Safety features at this property include a fire extinguisher, a security system, a first aid kit, and window guards Property Registration Number IT058091B4OUIRD7WF ### We should mention All guests, including children, must be present at check-in and show their government-issued photo ID card or passport Cash transactions at this property cannot exceed EUR 5000, due to national regulations; for further details, please contact the property using information in the booking confirmation The property has connecting/adjoining rooms, which are subject to availability and can be requested by contacting the property using the number on the booking confirmation ### Property is also known as Domus 21 Luxury Suites Rome Domus 21 Luxury Suites Guesthouse Domus 21 Luxury Suites Guesthouse Rome ## Frequently asked questions ### Is Domus 21 Luxury Suites pet-friendly? ### How much does it cost to stay at Domus 21 Luxury Suites? ### What time is check-in at Domus 21 Luxury Suites? ### What time is check-out at Domus 21 Luxury Suites? ### Does Domus 21 Luxury Suites provide a shuttle to the airport? ### Where is Domus 21 Luxury Suites located? ## Have a question? Beta Get instant answers with AI powered search of property information and reviews. Ask a question ## Reviews ## Domus 21 Luxury Suites Reviews 9.8 ### Exceptional All reviews shown are from real guest experiences. Only travellers who have booked a stay with us can submit a review. We verify reviews according to our guidelines and publish all reviews, positive or negative.[More information](https://www.expedia.ca/lp/b/content-guidelines) ### 10 Cleanliness ### 9.4 Amenities ### 9.8 Staff & service ### 9.6 Property conditions & facilities 10 - Excellent 79 8 - Good 12 6 - Okay 1 4 - Poor 0 2 - Terrible 1 ## Reviews ### 10/10 Excellent #### Heidi Oct 20, 2025 Liked: Cleanliness, staff & service, property conditions & facilities, room comfort Love this hotel!!! Awesome location, very nice inside, beds are super comfortable and staff was friendly and helpful! It also has a lift, which is great when u don’t pack light:-) They do not 24 reception so if you are arriving early or late you will just need to make arrangements. ##### Heidi Stayed 1 night in Oct 2025 ### 10/10 Excellent #### Deanna Jul 16, 2025 Liked: Cleanliness, amenities, property conditions & facilities Very lovely property! Close to so many restaurants, shopping, bus stops and site seeing. ##### Deanna Stayed 4 nights in Jun 2025 ### 10/10 Excellent #### Sean Aug 29, 2025 Liked: Cleanliness, staff & service, property conditions & facilities, room comfort #### Perfect Stay in Rome Great location. Super clean. Friendly staff. Comfy bed. Hot shower. Everything I needed for my stay in Rome. ##### Sean Stayed 1 night in Aug 2025 ### 10/10 Excellent #### diane Sep 27, 2025 Liked: Cleanliness, staff & service, amenities, property conditions & facilities This was a very unique and private property. The entrance was unsuspecting but easy to find. Once you went up the elevator and entered the guest services desk we were warmly welcomed. The room was very clean and the bed and linens very comfortable. We could not hear any street noise and had a pretty city view. ##### diane Stayed 3 nights in Sep 2025 ### 10/10 Excellent #### Jeffrey Apr 20, 2025 Liked: Cleanliness, staff & service, amenities, property conditions & facilities Nice staff. Great location ##### Jeffrey Stayed 1 night in Apr 2025 ### 10/10 Excellent #### Nhu Jun 24, 2025 Liked: Cleanliness, staff & service, amenities, property conditions & facilities This is exceptional space to spend time in Rome. The staff and rooms are superior. Their space is very aesthetic and the attention to detail in their design did not go unnoticed. I would not hesitate to stay here again! Thank you for the beautiful accommodations! ![](https://a.travel-assets.com/ugc/hotel-reviews/09e52724-20b5-4606-bb7e-a6699042786a-1750759981225.jpg?impolicy=resizecrop&rw=204&ra=fit&q=high) ![](https://a.travel-assets.com/ugc/hotel-reviews/a30607b1-5b79-4c1b-9121-bd6d1da6c1b9-1750759980726.jpg?impolicy=resizecrop&rw=204&ra=fit&q=high) ##### Nhu Stayed 1 night in Jun 2025 ### 10/10 Excellent #### Jose Apr 27, 2025 Liked: Cleanliness, staff & service, amenities, property conditions & facilities Excellent location and service. Even though the hotel doesn't have a 24 hr reception, the staff is invaluable with anything, and the size of the room and location are superb. ##### Jose Stayed 5 nights in Apr 2025 ### 10/10 Excellent #### Yuri Nov 20, 2024 Liked: Cleanliness, staff & service, amenities, property conditions & facilities Very good location and stylish ##### Yuri Stayed 2 nights in Nov 2024 ### 8/10 Good #### Caitlyn Jul 6, 2025 Liked: Cleanliness, staff & service, amenities, property conditions & facilities The property is in an excellent location. Walkable to many dining options and close to a lot of sight seeing. The suites are a little hard to find once you arrive and you have to go up the oldest and smallest elevator which was an Experience in itself! more directions prior Would have been helpful but overall it’s a great place for a quick trip in Rome! ##### Caitlyn Stayed 2 nights in Jun 2025 ### 10/10 Excellent #### Joshua Sep 1, 2025 Liked: Cleanliness, staff & service, property conditions & facilities, room comfort #### Excellent hotel One night stay in Rome before kicking off to the cruise ship. This was our first time in Rome. Amazing hotel! Had a great view, the ceiling is amazing, and the space was large and super clean. Super quiet had no problem sleeping at night, nor in the middle of the day nap as we were jet lagged getting here. The staff when we got here to check in, was so wonderful and inviting. This is definitely a place I am saving in my favorites to come back to again. Super great location, everything was very within walking distance. Newly married couple in our mid/upper 30s. ![](https://a.travel-assets.com/ugc/hotel-reviews/2040867d-849a-4c42-9ca3-815704c845ae-1756712847757.jpg?impolicy=resizecrop&rw=204&ra=fit&q=high) ![](https://a.travel-assets.com/ugc/hotel-reviews/7dbbaba0-6d70-4f53-8d6b-e9ebcfa310c6-1756712892235.jpg?impolicy=resizecrop&rw=204&ra=fit&q=high) ##### Joshua Stayed 1 night in Aug 2025 ### 10/10 Excellent #### Mikeala Oct 27, 2024 Liked: Cleanliness, staff & service, amenities, property conditions & facilities Lovely size rooms that are really clean and quiet. Great location and friendly reception staff ##### Mikeala Stayed 4 nights in Oct 2024 ### 8/10 Good #### Dennis Mar 25, 2025 Liked: Cleanliness, staff & service, amenities, property conditions & facilities Location, location, location. Great restaurants all around. Walkable to Trevi, the Colosseum and Pantheon. ##### Dennis Stayed 3 nights in Mar 2025 ### 10/10 Excellent #### Ira May 9, 2025 Liked: Cleanliness, staff & service, property conditions & facilities A five star experience in a well priced four star type property. Getting into place the first time is a bit of a challenge - street level passcode, up a flight of stairs to an old style elevator up to fifth floor - but once there, it's a lovely boutique property. Clean and front desk clerk very helpful. ##### Ira Stayed 2 nights in May 2025 ### 10/10 Excellent #### zeline Mar 11, 2024 Liked: Cleanliness, staff & service, amenities, property conditions & facilities Very nice rooms. good location. walkable to colusseum and many nice areas. ##### zeline Stayed 3 nights in Mar 2024 ### 8/10 Good #### Alison Sep 29, 2023 Liked: Cleanliness, staff & service, property conditions & facilities Fabulous location. Very quiet and peaceful room. ##### Alison Stayed 4 nights in Sep 2023 ### 10/10 Excellent #### Diana Aug 3, 2024 Liked: Cleanliness, staff & service, property conditions & facilities the staff was very attentive, nice, friendly, and welcoming, they also always made sure the room was always clean refilled my pear juice which was 10/10 ##### Diana Stayed 5 nights in Jul 2024 ### 10/10 Excellent #### Angela Jul 28, 2024 Liked: Cleanliness, staff & service, amenities, property conditions & facilities Clean and spacious. ##### Angela Stayed 2 nights in Jul 2024 ### 10/10 Excellent #### Anthony Feb 24, 2024 Liked: Cleanliness, staff & service, amenities, property conditions & facilities Lovely apartments with an attentive staff. They graciously allowed an early check in on our arrival. ##### Anthony ### 10/10 Excellent #### Verified traveller Jul 17, 2024 Liked: Cleanliness, staff & service, property conditions & facilities, room comfort #### Great room, fantastic service Only stayed one night but stay was fantastic. Front desk was very helpful in checking in, handling luggage early and planning transportation for us to the airport. Additional drinks/etc. that were already in the room were a bonus. Thanks for a great stay. ##### Verified traveller Stayed 1 night in Jul 2024 ### 10/10 Excellent #### Linda May 7, 2024 Liked: Cleanliness, staff & service, amenities, property conditions & facilities Everything was great, the location was awesome to walk to everything. There was a first foyer with security at the door so safety was wonderful. The room was spacious and the staff was very helpful with the luggage, assisted with tourist questions and walked me to my taxi to assure I was all set. Great stay and great staff. Such a great stay at a new property! ##### Linda Stayed 2 nights in May 2024 ### 10/10 Excellent #### Brandon Jul 19, 2024 Liked: Cleanliness, staff & service, property conditions & facilities, room comfort #### Perfect Our host was very hospitable, family-oriented, and kind. They accommodated us with very last minute reservations and our suite was extremely clean. Location was optimal also. We highly recommend this property! We were very pleased. ##### Brandon Stayed 1 night in Jul 2024 ### 10/10 Excellent #### David Sep 30, 2023 Liked: Cleanliness, staff & service, property conditions & facilities, room comfort #### Amazing Hotel!! This Hotel did not disappoint!! Exceptional! Staff, very friendly courteous and helpful! Great location and very easy to get to main attractions. We were there for eight days and we are so excited we will be returning there in a few days for another 3 nights! This little hotel was perfect! ##### David Stayed 8 nights in Sep 2023 ### 10/10 Excellent #### Darcy Jun 27, 2024 Really enjoyed our stay. Great location to walk to all the sights. Staff was lovely although not there all the time. Room was nice and great AC. An iron, water, coffee was provided daily. Our bathroom pocket door was difficult to close all the way, but otherwise I would have given it 5 stars. ##### Darcy Stayed 3 nights in Jun 2024 ### 6/10 Okay #### Peter Mar 2, 2025 Liked: Cleanliness, staff & service Disliked: Amenities, property conditions & facilities There are better options for staying in the center of Rome. the location is good and the bed is comfy but otherwise there is no reason to stay here. We could hear our very loud neighbors early in the morning. The maintenance of the room was lacking, i.e. toilet seat, shower soap dish, lighting etc. ##### Peter Stayed 2 nights in Feb 2025 ### 10/10 Excellent #### Reginald Aug 27, 2023 Liked: Amenities I would absolutely give this place a solid 4.5\. If they fix some minor things, it truly would be 5 stars. The staff, the location, the amenities are amazing. The rooms show a bit of wear and tear that could easily be addressed. If those were fixed, I’d give it 5 stars. ##### Reginald Stayed 2 nights in Aug 2023 ## Expedia's Latest Trends ### Hotels > [Mondo House](https://www.expedia.ca/Rome-Hotels-Mondo-House.h94990282.Hotel-Information) > > [Tiburtina Garden](https://www.expedia.ca/Rome-Hotels-Tiburtina-Garden.h18641924.Hotel-Information) > > [The Social Hub Rome](https://www.expedia.ca/Rome-Hotels-The-Social-Hub-Rome.h109576916.Hotel-Information) > > [LH Hotel Excel Roma Montemario](https://www.expedia.ca/Rome-Hotels-Excel-Roma-Montemario.h1436633.Hotel-Information) > > [Mancini Shabby House](https://www.expedia.ca/Rome-Hotels-Mancini-Shabby-House.h16399439.Hotel-Information) > > [Large Room with private bathroom and balcony on the green](https://www.expedia.ca/Rome-Hotels-Vrbo-Property.h85019014.Hotel-Information) > > [Rome Central Rooms Guest House o Affittacamere](https://www.expedia.ca/Rome-Hotels-Rome-Central-Rooms-Guest-House-O-Affittacamere.h30092903.Hotel-Information) > > [Old Bakery Guest house](https://www.expedia.ca/Rome-Hotels-Old-Bakery-Guest-House.h44433727.Hotel-Information) > > [Isabel Guest House](https://www.expedia.ca/Rome-Hotels-Isabel-Guest-House.h25122010.Hotel-Information) > > [La Dolce Sosta](https://www.expedia.ca/Rome-Hotels-La-Dolce-Sosta.h36866415.Hotel-Information) > > [SmooRooms Ostiense](https://www.expedia.ca/Rome-Hotels-SmooRooms.h24115971.Hotel-Information) > > [Noba Hotel e Residenze](https://www.expedia.ca/Rome-Hotels-Art-Hotel-Noba-Roma.h17171232.Hotel-Information) > > [Grand Hotel Tiberio](https://www.expedia.ca/Rome-Hotels-Grand-Hotel-Tiberio.h804299.Hotel-Information) > > [Parco Tirreno Residence](https://www.expedia.ca/Rome-Hotels-Parco-Tirreno-Residence.h1133769.Hotel-Information) > > [Veio Residence Resort](https://www.expedia.ca/Rome-Hotels-Veio-Residence-Resort.h2543364.Hotel-Information) > > [c-hotels Fiume](https://www.expedia.ca/Rome-Hotels-C-Hotels-Fiume.h1113564.Hotel-Information) > > [Best Western Cinemusic Hotel](https://www.expedia.ca/Rome-Hotels-Best-Western-Cinemusic-Hotel.h2191837.Hotel-Information) > > [Hotel Il Cantico St. Peter](https://www.expedia.ca/Rome-Hotels-Hotel-Il-Cantico-StPeter.h8171448.Hotel-Information) > > [Precise House Mantegna Roma](https://www.expedia.ca/Rome-Hotels-Precise-House-Mantegna-Roma.h1680767.Hotel-Information) > > [Basilica San Giovanni](https://www.expedia.ca/Rome-Hotels-Basilica-San-Giovanni.h30658928.Hotel-Information) > > [Ergife Palace Hotel](https://www.expedia.ca/Rome-Hotels-Ergife-Palace-Hotel.h2206430.Hotel-Information) > > [Hilton Rome Eur La Lama](https://www.expedia.ca/Rome-Hotels-Hilton-Rome-Eur-Convention-Center.h44681998.Hotel-Information) > > [hu Roma Camping In Town](https://www.expedia.ca/Rome-Hotels-Roma-Camping-In-Town.h4161322.Hotel-Information) > > [Courtyard by Marriott Rome Central Park](https://www.expedia.ca/Rome-Hotels-Courtyard-Rome-Central-Park.h804624.Hotel-Information) > > [Le Lanterne B&B](https://www.expedia.ca/Rome-Hotels-Le-Lanterne-BB.h17519503.Hotel-Information) > > [Trastevere Gallery Suites](https://www.expedia.ca/Rome-Hotels-Trastevere-Gallery-Suites.h35201137.Hotel-Information) > > [Hotel Principe Torlonia](https://www.expedia.ca/Rome-Hotels-Hotel-Principe-Torlonia-A-Member-Of-Elizabeth-Hotel-Group.h1819319.Hotel-Information) > > [Hotel Cristoforo Colombo](https://www.expedia.ca/Rome-Hotels-Hotel-Cristoforo-Colombo.h108783.Hotel-Information) > > [Hotel Valeri](https://www.expedia.ca/Rome-Hotels-Hotel-Valeri.h2690372.Hotel-Information)