Title: Book the Best Potrero LUXURY Hotels - Upscale Hotels in Potrero, CA | Expedia.ca [Hotels in Potrero](https://expedia.ca/Potrero-Hotels.d553248635122512057.Travel-Guide-Hotels)[Vacation Rentals in Potrero](https://expedia.ca/Potrero-Vacation-Rentals.d553248635122512057.Travel-Guide-VacationRentals)[Potrero Car Rentals](https://expedia.ca/Car-Rentals-In-Potrero.d553248635122512057.Car-Rental-Guide)[Potrero Vacation Packages](https://expedia.ca/Potrero.d553248635122512057.Destination-Travel-Guides) ![Default HTG hotel image](https://a.travel-assets.com/travel-assets-manager/bex-affinities/luxury.jpeg?impolicy=fcrop&w=1200&h=500&q=medium) # Find luxury hotels in Potrero, CA - ![](https://a.travel-assets.com/travel-assets-manager/pictogram-bex/light__calendar_shield.svg) ### Change your mind Book hotels with free cancellation - ![](https://a.travel-assets.com/travel-assets-manager/pictogram-bex/light__deals.svg) ### Treat yourself Sign in to save 10% or more on thousands of hotels [Sign in](https://www.expedia.ca/login) - ![](https://a.travel-assets.com/travel-assets-manager/pictogram-bex/light__bed.svg) ### Be picky Search almost a million properties worldwide ## Check availability on Potrero Luxury Hotels Tonight [Dec 27 - Dec 28](https://www.expedia.ca/Hotel-Search?regionId=553248635122512057&startDate=2025-12-27&endDate=2025-12-28&adults=2&propertyStyle=LUXURY&rfrr=TG.LP.CheckPrices.Hotel&openPlayBack=true&travelerType=luxury_property) Tomorrow [Dec 28 - Dec 29](https://www.expedia.ca/Hotel-Search?regionId=553248635122512057&startDate=2025-12-28&endDate=2025-12-29&adults=2&propertyStyle=LUXURY&rfrr=TG.LP.CheckPrices.Hotel&openPlayBack=true&travelerType=luxury_property) Next weekend [Jan 2 - Jan 4](https://www.expedia.ca/Hotel-Search?regionId=553248635122512057&startDate=2026-01-02&endDate=2026-01-04&adults=2&propertyStyle=LUXURY&rfrr=TG.LP.CheckPrices.Hotel&openPlayBack=true&travelerType=luxury_property) In two weeks [Jan 9 - Jan 11](https://www.expedia.ca/Hotel-Search?regionId=553248635122512057&startDate=2026-01-09&endDate=2026-01-11&adults=2&propertyStyle=LUXURY&rfrr=TG.LP.CheckPrices.Hotel&openPlayBack=true&travelerType=luxury_property) ## Top Potrero Hotel Reviews ![Viejas Casino & Willows Hotel](https://images.trvl-media.com/lodging/7000000/6640000/6636200/6636137/09e977a6_y.jpg) ### Viejas Casino & Willows Hotel 10/10 Excellent "This is a lovely property that has the feeling of being far from home, even though it’s just a short drive up into the mountain. Plus, it’s a casino with all the amenities of a casino. Two thumbs up." [](https://expedia.ca/Alpine-Hotels-Viejas-Casino-Willows-Hotel.h6636137.Hotel-Information) ![Ayres Lodge Alpine](https://images.trvl-media.com/lodging/1000000/60000/50100/50032/089f0b78_y.jpg) ### Ayres Lodge Alpine 10/10 Excellent "Love the area, the staff and clean rooms. " [](https://expedia.ca/Alpine-Hotels-Ayres-Lodge-Alpine.h50032.Hotel-Information) ![Quality Suites San Diego Otay Mesa](https://images.trvl-media.com/lodging/1000000/470000/461900/461837/673df2c4_y.jpg) ### Quality Suites San Diego Otay Mesa 10/10 Excellent "Dd" [](https://expedia.ca/San-Diego-Hotels-Quality-Suites-San-Diego-Otay-Mesa.h461837.Hotel-Information) ![Vineyard Hacienda](https://images.trvl-media.com/lodging/9000000/8790000/8782500/8782409/da8f2406_y.jpg) ### Vineyard Hacienda 10/10 Excellent "Such a sweet hidden gem!!! Staff was amazing!! " [](https://expedia.ca/Spring-Valley-Hotels-Vineyard-Hacienda.h8782409.Hotel-Information) ## Frequently asked questions ### Are you looking for a luxury hotel for your Potrero vacation? ### When can I expect good weather in Potrero? ### What's there to see and do in Potrero? ## Explore a world of travel with Expedia - Lodging - More ways to book - [Boutique Hotels in Alpine ](https://www.expedia.ca/Alpine-Hotels-Boutique-Hotel.0-0-d55547-tBoutiqueHotel.Travel-Guide-Filter-Hotels) - [Cheap Hotels in Alpine ](https://www.expedia.ca/Alpine-Hotels-Cheap-Hotels.0-0-d55547-tCheapHotels.Travel-Guide-Filter-Hotels) - [Luxury Hotels in Alpine ](https://www.expedia.ca/Alpine-Hotels-Luxury-Hotel.0-0-d55547-tLuxuryHotel.Travel-Guide-Filter-Hotels) - [Mountain Hotels in Alpine ](https://www.expedia.ca/Alpine-Hotels-Mountain-Hotels.0-0-d55547-tMountainHotels.Travel-Guide-Filter-Hotels) - [Pet-Friendly Hotels in Alpine ](https://www.expedia.ca/Alpine-Hotels-Pet-Friendly-Hotel.0-0-d55547-tPetfriendlyHotel.Travel-Guide-Filter-Hotels) - 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