Title: Book the Best BUSINESS Hotels in Port Isabel in 2026 | Expedia.ca [Port Isabel Travel Guide](https://expedia.ca/Port-Isabel.dx184007)[Hotels in Port Isabel](https://expedia.ca/Port-Isabel-Hotels.d184007.Travel-Guide-Hotels)[Vacation Rentals in Port Isabel](https://expedia.ca/Port-Isabel-Vacation-Rentals.d184007.Travel-Guide-VacationRentals)[Flights to Port Isabel](https://expedia.ca/Cheap-Flights-To-Port-Isabel.d184007.Travel-Guide-Flights)[Things to do in Port Isabel](https://expedia.ca/Things-To-Do-In-Port-Isabel.d184007.Travel-Guide-Activities)[Port Isabel Car Rentals](https://expedia.ca/Car-Rentals-In-Port-Isabel.d184007.Car-Rental-Guide)[Port Isabel Vacation Packages](https://expedia.ca/Port-Isabel.d184007.Destination-Travel-Guides) ![Port Isabel](https://images.trvl-media.com/place/184007/bd9c1ec3-f2dc-45ab-829d-76b09b3a2356.jpg?impolicy=fcrop&w=1200&h=500&q=medium) # Find Business Hotels in Port Isabel, TX from CA $67 - ![](https://a.travel-assets.com/travel-assets-manager/pictogram-bex/light__calendar_shield.svg) ### Change your mind Book hotels with free cancellation - ![](https://a.travel-assets.com/travel-assets-manager/pictogram-bex/light__deals.svg) ### Treat yourself Sign in to save 10% or more on thousands of hotels [Sign in](https://www.expedia.ca/login) - ![](https://a.travel-assets.com/travel-assets-manager/pictogram-bex/light__bed.svg) ### Be picky Search almost a million properties worldwide ## Check availability on Port Isabel Business Hotels Tonight [Dec 11 - Dec 12](https://www.expedia.ca/Hotel-Search?regionId=184007&startDate=2025-12-11&endDate=2025-12-12&adults=2&rfrr=TG.LP.CheckPrices.Hotel&openPlayBack=true&travelerType=business_friendly) Tomorrow [Dec 12 - Dec 13](https://www.expedia.ca/Hotel-Search?regionId=184007&startDate=2025-12-12&endDate=2025-12-13&adults=2&rfrr=TG.LP.CheckPrices.Hotel&openPlayBack=true&travelerType=business_friendly) This weekend [Dec 12 - Dec 14](https://www.expedia.ca/Hotel-Search?regionId=184007&startDate=2025-12-12&endDate=2025-12-14&adults=2&rfrr=TG.LP.CheckPrices.Hotel&openPlayBack=true&travelerType=business_friendly) Next weekend [Dec 19 - Dec 21](https://www.expedia.ca/Hotel-Search?regionId=184007&startDate=2025-12-19&endDate=2025-12-21&adults=2&rfrr=TG.LP.CheckPrices.Hotel&openPlayBack=true&travelerType=business_friendly) ## Our top choices for Port Isabel business-friendly hotels ![Reception](https://images.trvl-media.com/lodging/2000000/1230000/1224900/1224844/b66aa217.jpg?impolicy=fcrop&w=357&h=201&p=1&q=medium) ![Front of property](https://images.trvl-media.com/lodging/2000000/1230000/1224900/1224844/27e1c1e8.jpg?impolicy=fcrop&w=357&h=201&p=1&q=medium) ![Outdoor pool, open 7:00 AM to 10:00 PM, sun loungers](https://images.trvl-media.com/lodging/2000000/1230000/1224900/1224844/6cc9bc46.jpg?impolicy=fcrop&w=357&h=201&p=1&q=medium) ![Reception](https://images.trvl-media.com/lodging/2000000/1230000/1224900/1224844/4caa06c5.jpg?impolicy=fcrop&w=357&h=201&p=1&q=medium) ### Casa Rosa Inn [](https://www.expedia.ca/South-Padre-Island-Hotels-Casa-Rosa-Inn.h1224844.Hotel-Information) Port Isabel 7.8/10 Good (535) "Bed and room were comfortable loved our stay " ![United States](https://a.travel-assets.com/egds/marks/flags/us.svg) Kimberly CA $82 CA $110 total includes taxes & fees Dec 15 - Dec 16 [](https://www.expedia.ca/South-Padre-Island-Hotels-Casa-Rosa-Inn.h1224844.Hotel-Information) ![Outdoor pool, sun loungers](https://images.trvl-media.com/lodging/1000000/30000/22000/21996/6c66ea1a.jpg?impolicy=fcrop&w=357&h=201&p=1&q=medium) ![Lobby](https://images.trvl-media.com/lodging/1000000/30000/22000/21996/b3aed2b5.jpg?impolicy=fcrop&w=357&h=201&p=1&q=medium) ![Condo, 2 Bedrooms | Living area](https://images.trvl-media.com/lodging/1000000/30000/22000/21996/c73d830f.jpg?impolicy=fcrop&w=357&h=201&p=1&q=medium) ![View from room](https://images.trvl-media.com/lodging/1000000/30000/22000/21996/d805ab5c.jpg?impolicy=fcrop&w=357&h=201&p=1&q=medium) ### Margaritaville Beach Resort South Padre Island [](https://www.expedia.ca/South-Padre-Island-Hotels-Pearl-South-Padre.h21996.Hotel-Information) South Padre Island 8.6/10 Excellent (1890) "The stay was amazing!" ![United States](https://a.travel-assets.com/egds/marks/flags/us.svg) Marlyn CA $80 CA $106 total includes taxes & fees Jan 5 - Jan 6, 2026 [](https://www.expedia.ca/South-Padre-Island-Hotels-Pearl-South-Padre.h21996.Hotel-Information) ![Free on-the-go breakfast](https://images.trvl-media.com/lodging/1000000/800000/797300/797201/90b731a3.jpg?impolicy=fcrop&w=357&h=201&p=1&q=medium) ![Lobby](https://images.trvl-media.com/lodging/1000000/800000/797300/797201/e448c24a.jpg?impolicy=fcrop&w=357&h=201&p=1&q=medium) ![Standard Room, 1 King Bed, Non Smoking, Refrigerator & Microwave](https://images.trvl-media.com/lodging/1000000/800000/797300/797201/0719c44e.jpg?impolicy=fcrop&w=357&h=201&p=1&q=medium) ![Outdoor pool, sun loungers](https://images.trvl-media.com/lodging/1000000/800000/797300/797201/2e4f4ac8.jpg?impolicy=fcrop&w=357&h=201&p=1&q=medium) ### Best Western Beachside Inn [](https://www.expedia.ca/South-Padre-Island-Hotels-Best-Western-Beachside-Inn.h797201.Hotel-Information) South Padre Island 8.6/10 Excellent (1008) "Clean, best Staff, good stay" ![United States](https://a.travel-assets.com/egds/marks/flags/us.svg) Patricio CA $70 CA $82 total includes taxes & fees Dec 17 - Dec 18 [](https://www.expedia.ca/South-Padre-Island-Hotels-Best-Western-Beachside-Inn.h797201.Hotel-Information) ![Lobby](https://images.trvl-media.com/lodging/1000000/50000/43000/42960/3e3ed8a5.jpg?impolicy=fcrop&w=357&h=201&p=1&q=medium) ![Lobby](https://images.trvl-media.com/lodging/1000000/50000/43000/42960/4c8db27c.jpg?impolicy=fcrop&w=357&h=201&p=1&q=medium) ![Individually furnished, desk, laptop workspace, blackout drapes](https://images.trvl-media.com/lodging/1000000/50000/43000/42960/6a8f3ca2.jpg?impolicy=fcrop&w=357&h=201&p=1&q=medium) ![Restaurant](https://images.trvl-media.com/lodging/1000000/50000/43000/42960/097d23be.jpg?impolicy=fcrop&w=357&h=201&p=1&q=medium) ### SureStay Hotel by Best Western Brownsville [](https://www.expedia.ca/Brownsville-Hotels-SureStay-Hotel-By-Best-Western-Brownsville.h42960.Hotel-Information) Brownsville 7.6/10 Good (554) "Clean room, but the breakfast could be a little bit better" ![United States](https://a.travel-assets.com/egds/marks/flags/us.svg) Ana CA $98 CA $113 total includes taxes & fees Dec 14 - Dec 15 [](https://www.expedia.ca/Brownsville-Hotels-SureStay-Hotel-By-Best-Western-Brownsville.h42960.Hotel-Information) ![BBQ/picnic area](https://images.trvl-media.com/lodging/2000000/1100000/1092000/1091955/3cb95f03.jpg?impolicy=fcrop&w=357&h=201&p=1&q=medium) ![50-inch LCD TV with cable channels, TV](https://images.trvl-media.com/lodging/2000000/1100000/1092000/1091955/acf566d1.jpg?impolicy=fcrop&w=357&h=201&p=1&q=medium) ![Standard Double Room, Beach View | Balcony](https://images.trvl-media.com/lodging/2000000/1100000/1092000/1091955/ea092c0a.jpg?impolicy=fcrop&w=357&h=201&p=1&q=medium) ![Standard Double Room, Pool View | View from room](https://images.trvl-media.com/lodging/2000000/1100000/1092000/1091955/032e3ef3.jpg?impolicy=fcrop&w=357&h=201&p=1&q=medium) ### La Copa Inn Beach Hotel [](https://www.expedia.ca/South-Padre-Island-Hotels-La-Copa-Inn-Beach-Hotel.h1091955.Hotel-Information) South Padre Island 8.8/10 Excellent (1682) "Great place " ![United States](https://a.travel-assets.com/egds/marks/flags/us.svg) priscilla CA $79 CA $99 total includes taxes & fees Dec 21 - Dec 22 [](https://www.expedia.ca/South-Padre-Island-Hotels-La-Copa-Inn-Beach-Hotel.h1091955.Hotel-Information) ![Exterior](https://images.trvl-media.com/lodging/44000000/43520000/43511700/43511682/65716f72.jpg?impolicy=fcrop&w=357&h=201&p=1&q=medium) ![Outdoor pool, open 9:00 AM to 10:00 PM, pool umbrellas, sun loungers](https://images.trvl-media.com/lodging/44000000/43520000/43511700/43511682/5e6cd851.jpg?impolicy=fcrop&w=357&h=201&p=1&q=medium) ![2 bars/lounges, poolside bar, beach bar](https://images.trvl-media.com/lodging/44000000/43520000/43511700/43511682/1a240572.jpg?impolicy=fcrop&w=357&h=201&p=1&q=medium) ![Suite, Multiple Beds, Ocean View (Balcony)](https://images.trvl-media.com/lodging/44000000/43520000/43511700/43511682/c284a13c.jpg?impolicy=fcrop&w=357&h=201&p=1&q=medium) ### Courtyard by Marriott South Padre Island [](https://www.expedia.ca/South-Padre-Island-Hotels-Courtyard-By-Marriott-South-Padre-Island.h43511682.Hotel-Information) North End 8.8/10 Excellent (1641) "Was a pleasant stay this time of year. " ![United States](https://a.travel-assets.com/egds/marks/flags/us.svg) Carlos CA $105 CA $123 total includes taxes & fees Dec 16 - Dec 17 [](https://www.expedia.ca/South-Padre-Island-Hotels-Courtyard-By-Marriott-South-Padre-Island.h43511682.Hotel-Information) ![In-room safe, desk, laptop workspace, iron/ironing board](https://images.trvl-media.com/lodging/4000000/3510000/3508900/3508863/4b34cca3.jpg?impolicy=fcrop&w=357&h=201&p=1&q=medium) ![Bar (on property)](https://images.trvl-media.com/lodging/4000000/3510000/3508900/3508863/cca93753.jpg?impolicy=fcrop&w=357&h=201&p=1&q=medium) ![Exterior](https://images.trvl-media.com/lodging/4000000/3510000/3508900/3508863/fcc1e829.jpg?impolicy=fcrop&w=357&h=201&p=1&q=medium) ![View from room](https://images.trvl-media.com/lodging/4000000/3510000/3508900/3508863/a7c9c9bc.jpg?impolicy=fcrop&w=357&h=201&p=1&q=medium) ### Hilton Garden Inn South Padre Island Beachfront [](https://www.expedia.ca/South-Padre-Island-Hotels-Hilton-Garden-Inn-South-Padre-Island-Beachfront.h3508863.Hotel-Information) North End 8.8/10 Excellent (1004) "The room was perfect, staff awesome." ![United States](https://a.travel-assets.com/egds/marks/flags/us.svg) Linda CA $105 CA $123 total includes taxes & fees Dec 22 - Dec 23 [](https://www.expedia.ca/South-Padre-Island-Hotels-Hilton-Garden-Inn-South-Padre-Island-Beachfront.h3508863.Hotel-Information) ![Reception](https://images.trvl-media.com/lodging/1000000/450000/440500/440474/52e547bb.jpg?impolicy=fcrop&w=357&h=201&p=1&q=medium) ![In-room safe, desk, blackout drapes, iron/ironing board](https://images.trvl-media.com/lodging/1000000/450000/440500/440474/fe690600.jpg?impolicy=fcrop&w=357&h=201&p=1&q=medium) ![Lobby](https://images.trvl-media.com/lodging/1000000/450000/440500/440474/f24ded53.jpg?impolicy=fcrop&w=357&h=201&p=1&q=medium) ![Exterior](https://images.trvl-media.com/lodging/1000000/450000/440500/440474/d18adaa5.jpg?impolicy=fcrop&w=357&h=201&p=1&q=medium) ### Super 8 by Wyndham South Padre Island [](https://www.expedia.ca/South-Padre-Island-Hotels-Super-8-By-Wyndham-South-Padre-Island.h440474.Hotel-Information) South Padre Island 7.2/10 Good (1000) "Clean room quiet place " ![United States](https://a.travel-assets.com/egds/marks/flags/us.svg) Minerva CA $52 CA $67 total includes taxes & fees Dec 22 - Dec 23 [](https://www.expedia.ca/South-Padre-Island-Hotels-Super-8-By-Wyndham-South-Padre-Island.h440474.Hotel-Information) ![Honeymoon Room - King Bed with Jacuzzi](https://images.trvl-media.com/lodging/77000000/76150000/76149600/76149536/625a2eeb.jpg?impolicy=fcrop&w=357&h=201&p=1&q=medium) ![Outdoor pool, open 10:00 AM to 10:00 PM, pool umbrellas, sun loungers](https://images.trvl-media.com/lodging/77000000/76150000/76149600/76149536/77795698.jpg?impolicy=fcrop&w=357&h=201&p=1&q=medium) ![Property grounds](https://images.trvl-media.com/lodging/77000000/76150000/76149600/76149536/dc901218.jpg?impolicy=fcrop&w=357&h=201&p=1&q=medium) ![Interior entrance](https://images.trvl-media.com/lodging/77000000/76150000/76149600/76149536/6db1a3cc.jpg?impolicy=fcrop&w=357&h=201&p=1&q=medium) ### El Delfín Lodge [](https://www.expedia.ca/South-Padre-Island-Hotels-El-Delfin-Lodge.h76149536.Hotel-Information) North End 9.0/10 Wonderful (1212) "Staff was friendly and the hotel was quiet" ![United States](https://a.travel-assets.com/egds/marks/flags/us.svg) Max CA $55 CA $72 total includes taxes & fees Dec 14 - Dec 15 [](https://www.expedia.ca/South-Padre-Island-Hotels-El-Delfin-Lodge.h76149536.Hotel-Information) ![Beach nearby](https://images.trvl-media.com/lodging/2000000/1200000/1194400/1194363/7707ef05.jpg?impolicy=fcrop&w=357&h=201&p=1&q=medium) ![Beach nearby](https://images.trvl-media.com/lodging/2000000/1200000/1194400/1194363/df2450b5.jpg?impolicy=fcrop&w=357&h=201&p=1&q=medium) ![Exterior](https://images.trvl-media.com/lodging/2000000/1200000/1194400/1194363/741a110e.jpg?impolicy=fcrop&w=357&h=201&p=1&q=medium) ![Lobby](https://images.trvl-media.com/lodging/2000000/1200000/1194400/1194363/f73da4cd.jpg?impolicy=fcrop&w=357&h=201&p=1&q=medium) ### Holiday Inn Express Hotel & Suites South Padre Island by IHG [](https://www.expedia.ca/South-Padre-Island-Hotels-Holiday-Inn-Express-Hotel-Suites-South-Padre-Island.h1194363.Hotel-Information) North End 9.0/10 Wonderful (1138) "The stay was great as usual, its always a pleasure at HI!" ![United States](https://a.travel-assets.com/egds/marks/flags/us.svg) Rosie CA $91 CA $106 total includes taxes & fees Dec 14 - Dec 15 [](https://www.expedia.ca/South-Padre-Island-Hotels-Holiday-Inn-Express-Hotel-Suites-South-Padre-Island.h1194363.Hotel-Information) Lowest nightly price found within the past 24 hours based on a 1 night stay for 2 adults. Prices and availability subject to change. Additional terms may apply. [View all properties](https://expedia.ca/Hotel-Search?startDate=2025-12-25&endDate=2025-12-26®ionId=184007&adults=2&travelerType=business_friendly&sort=RECOMMENDED&openPlayBack=true) ## Top Port Isabel Hotel Reviews ![Ramada by Wyndham & Suites South Padre Island](https://images.trvl-media.com/lodging/1000000/570000/564800/564779/6f29f952_y.jpg) ### Ramada by Wyndham & Suites South Padre Island 10/10 Excellent "Todo estuvo muy bien, el cuarto con varias camas estuvo hermoso y limpio sin ningún problema como siempre que vamos ahí " [](https://expedia.ca/South-Padre-Island-Hotels-Ramada-By-Wyndham-Suites-South-Padre-Island.h564779.Hotel-Information) ![Holiday Inn Resort South Padre Island - Beach Front by IHG](https://images.trvl-media.com/lodging/1000000/10000/9700/9670/6c276cc6_y.jpg) ### Holiday Inn Resort South Padre Island - Beach Front by IHG 10/10 Excellent "We did not eat breakfast at the hotel." [](https://expedia.ca/South-Padre-Island-Hotels-Beach-Resort-At-South-Padre-Island.h9670.Hotel-Information) ![Hilton Garden Inn South Padre Island Beachfront](https://images.trvl-media.com/lodging/4000000/3510000/3508900/3508863/a7c9c9bc_y.jpg) ### Hilton Garden Inn South Padre Island Beachfront 10/10 Excellent "The breakfast food was cold. We didn't use the pool or hot tub. The staff was Wonderful!!!!" [](https://expedia.ca/South-Padre-Island-Hotels-Hilton-Garden-Inn-South-Padre-Island-Beachfront.h3508863.Hotel-Information) ![La Copa Inn Beach Hotel](https://images.trvl-media.com/lodging/2000000/1100000/1092000/1091955/8c0e83db_y.jpg) ### La Copa Inn Beach Hotel 10/10 Excellent "I liked it" [](https://expedia.ca/South-Padre-Island-Hotels-La-Copa-Inn-Beach-Hotel.h1091955.Hotel-Information) ![Holiday Inn Express Hotel & Suites South Padre Island by IHG](https://images.trvl-media.com/lodging/2000000/1200000/1194400/1194363/491fbc64_y.jpg) ### Holiday Inn Express Hotel & Suites South Padre Island by IHG 10/10 Excellent "The stay was great as usual, its always a pleasure at HI!" [](https://expedia.ca/South-Padre-Island-Hotels-Holiday-Inn-Express-Hotel-Suites-South-Padre-Island.h1194363.Hotel-Information) ![WindWater Hotel and Marina](https://images.trvl-media.com/lodging/1000000/10000/5600/5510/c69527ca_y.jpg) ### WindWater Hotel and Marina 10/10 Excellent "To start off if I could rate this hotel 10 stars I would ! The staff was very welcoming & happy to assist us on our stay. The room was clean and neat had no issues at all. I will definitely be booking again very soon. Also that staff needs to get a raise cause of them is the reason I'll be returning soon." [](https://expedia.ca/South-Padre-Island-Hotels-WindWater-Hotel-Marina.h5510.Hotel-Information) ![Margaritaville Beach Resort South Padre Island ](https://images.trvl-media.com/lodging/1000000/30000/22000/21996/6db563a5_y.jpg) ### Margaritaville Beach Resort South Padre Island 10/10 Excellent "Room was awesome, will certainly be back, thank you.. " [](https://expedia.ca/South-Padre-Island-Hotels-Pearl-South-Padre.h21996.Hotel-Information) ![Sunchase Inn & Suites](https://images.trvl-media.com/lodging/3000000/2360000/2351100/2351046/2deabedf_y.jpg) ### Sunchase Inn & Suites 10/10 Excellent "Clean and friendly " [](https://expedia.ca/South-Padre-Island-Hotels-Suites-At-Sunchase.h2351046.Hotel-Information) ![Best Western Beachside Inn](https://images.trvl-media.com/lodging/1000000/800000/797300/797201/e448c24a_y.jpg) ### Best Western Beachside Inn 10/10 Excellent "Great,been here many times before,great as always." [](https://expedia.ca/South-Padre-Island-Hotels-Best-Western-Beachside-Inn.h797201.Hotel-Information) ## Frequently asked questions ### How much do business-friendly hotels in Port Isabel cost? ### What are the best business-friendly hotels in Port Isabel? ### How many business-friendly hotels are there in Port Isabel? ### What are the best cheap business-friendly hotels in Port Isabel? ### What are the top business-friendly motels in Port Isabel? ### Are there any family-friendly hotels in Port Isabel that are also business friendly? ### Why book your business-friendly hotel in Port Isabel with Expedia? ### How can I find cheap business-friendly hotels in Port Isabel? ### What is there to do in Port Isabel near my business-friendly hotel? ## Explore a world of travel with Expedia - Lodging - Flights - Packages - Cars - Vacation Rental - More ways to book - [5 Star Hotels in South Padre Island ](https://www.expedia.ca/5Star-South-Padre-Island-Hotels.s50-0-d6046797.Travel-Guide-Filter-Hotels) - 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