Title: Book the Best Plantation Key SPA Resorts from CA $523 - Spa Hotels in Plantation Key, FL | Expedia.ca [Plantation Key Travel Guide](https://expedia.ca/Plantation-Key.dx553248635083898347)[Hotels in Plantation Key](https://expedia.ca/Plantation-Key-Hotels.d553248635083898347.Travel-Guide-Hotels)[Vacation Rentals in Plantation Key](https://expedia.ca/Plantation-Key-Vacation-Rentals.d553248635083898347.Travel-Guide-VacationRentals)[Flights to Plantation Key](https://expedia.ca/Cheap-Flights-To-Plantation-Key.d553248635083898347.Travel-Guide-Flights)[Things to do in Plantation Key](https://expedia.ca/Things-To-Do-In-Plantation-Key.d553248635083898347.Travel-Guide-Activities)[Plantation Key Car Rentals](https://expedia.ca/Car-Rentals-In-Plantation-Key.d553248635083898347.Car-Rental-Guide)[Plantation Key Vacation Packages](https://expedia.ca/Plantation-Key.d553248635083898347.Destination-Travel-Guides) ![Plantation Key showing a river or creek](https://images.trvl-media.com/place/553248635083898347/d14a3e79-a6a5-4f2f-9617-637300735959.jpg?impolicy=fcrop&w=1200&h=500&q=medium) ![](https://images.trvl-media.com/place/553248635083898347/d14a3e79-a6a5-4f2f-9617-637300735959.jpg?impolicy=fcrop&w=1200&h=500&q=medium) - ![](https://a.travel-assets.com/travel-assets-manager/pictogram-bex/light__calendar_shield.svg) ### Change your mind Book hotels with free cancellation - ![](https://a.travel-assets.com/travel-assets-manager/pictogram-bex/light__deals.svg) ### Treat yourself Sign in to save 10% or more on thousands of hotels [Sign in](https://www.expedia.ca/login) - ![](https://a.travel-assets.com/travel-assets-manager/pictogram-bex/light__bed.svg) ### Be picky Search almost a million properties worldwide ## Check availability on Plantation Key Spa Hotels Tonight [Mar 16 - Mar 17](https://www.expedia.ca/Hotel-Search?regionId=553248635083898347&startDate=2026-03-16&endDate=2026-03-17&adults=2&amenities=SPA_ON_SITE&rfrr=TG.LP.CheckPrices.Hotel&openPlayBack=true) Tomorrow [Mar 17 - Mar 18](https://www.expedia.ca/Hotel-Search?regionId=553248635083898347&startDate=2026-03-17&endDate=2026-03-18&adults=2&amenities=SPA_ON_SITE&rfrr=TG.LP.CheckPrices.Hotel&openPlayBack=true) This weekend [Mar 20 - Mar 22](https://www.expedia.ca/Hotel-Search?regionId=553248635083898347&startDate=2026-03-20&endDate=2026-03-22&adults=2&amenities=SPA_ON_SITE&rfrr=TG.LP.CheckPrices.Hotel&openPlayBack=true) Next weekend [Mar 27 - Mar 29](https://www.expedia.ca/Hotel-Search?regionId=553248635083898347&startDate=2026-03-27&endDate=2026-03-29&adults=2&amenities=SPA_ON_SITE&rfrr=TG.LP.CheckPrices.Hotel&openPlayBack=true) ## Our top choices for Plantation Key hotels with a spa ![Fitness facility](https://images.trvl-media.com/lodging/1000000/10000/5800/5780/3a93482b.jpg?impolicy=fcrop&w=357&h=201&p=1&q=medium) ![Property grounds](https://images.trvl-media.com/lodging/1000000/10000/5800/5780/981feca1.jpg?impolicy=fcrop&w=357&h=201&p=1&q=medium) ![Poolside bar](https://images.trvl-media.com/lodging/1000000/10000/5800/5780/387633fc.jpg?impolicy=fcrop&w=357&h=201&p=1&q=medium) ![Daily full breakfast for a fee](https://images.trvl-media.com/lodging/1000000/10000/5800/5780/b210c979.jpg?impolicy=fcrop&w=357&h=201&p=1&q=medium) ### Cheeca Lodge & Spa [](https://www.expedia.ca/Islamorada-Hotels-Cheeca-Lodge-Spa.h5780.Hotel-Information) Matecumbe 9.2/10 Wonderful (1,298 reviews) "Great staff and beautiful property " ![United States](https://a.travel-assets.com/egds/marks/flags/us.svg) Julie CA $424 CA $578 total includes taxes & fees Apr 12 - Apr 13 [](https://www.expedia.ca/Islamorada-Hotels-Cheeca-Lodge-Spa.h5780.Hotel-Information) ![Body treatments, aromatherapy, hot stone massages, deep-tissue massages](https://images.trvl-media.com/lodging/1000000/10000/3500/3427/c2842ab0.jpg?impolicy=fcrop&w=357&h=201&p=1&q=medium) ![Private beach, white sand, sun loungers, beach umbrellas](https://images.trvl-media.com/lodging/1000000/10000/3500/3427/e9f2dff3.jpg?impolicy=fcrop&w=357&h=201&p=1&q=medium) ![Beach views, serves lunch, dinner, and happy hour](https://images.trvl-media.com/lodging/1000000/10000/3500/3427/9cf56c63.jpg?impolicy=fcrop&w=357&h=201&p=1&q=medium) ![Poolside bar](https://images.trvl-media.com/lodging/1000000/10000/3500/3427/b2a768a3.jpg?impolicy=fcrop&w=357&h=201&p=1&q=medium) ### Reefhouse Resort & Marina [](https://www.expedia.ca/Key-Largo-Hotels-Reefhouse-Resort-Marina.h3427.Hotel-Information) Key Largo 9.2/10 Wonderful (1,386 reviews) "Clean rooms, nice staff, great beach area." ![United States](https://a.travel-assets.com/egds/marks/flags/us.svg) Brittany CA $520 CA $640 total includes taxes & fees Apr 12 - Apr 13 [](https://www.expedia.ca/Key-Largo-Hotels-Reefhouse-Resort-Marina.h3427.Hotel-Information) ![Sauna, hot tub, steam room, body treatments, hot stone massages](https://images.trvl-media.com/lodging/12000000/11920000/11919100/11919055/53b9e2c0.jpg?impolicy=fcrop&w=357&h=201&p=1&q=medium) ![Serves lunch and dinner](https://images.trvl-media.com/lodging/12000000/11920000/11919100/11919055/bb9d7ce2.jpg?impolicy=fcrop&w=357&h=201&p=1&q=medium) ![On the beach, beach cabanas, sun loungers, beach umbrellas](https://images.trvl-media.com/lodging/12000000/11920000/11919100/11919055/d9cc2f68.jpg?impolicy=fcrop&w=357&h=201&p=1&q=medium) ![Outdoor pool, cabanas (surcharge), pool umbrellas](https://images.trvl-media.com/lodging/12000000/11920000/11919100/11919055/ba58782b.jpg?impolicy=fcrop&w=357&h=201&p=1&q=medium) ### Playa Largo Resort & Spa, Autograph Collection [](https://www.expedia.ca/Key-Largo-Hotels-Playa-Largo-Resort-Spa.h11919055.Hotel-Information) Rock Harbor 8.8/10 Excellent (1,005 reviews) "We had a wonderful six night stay at Playa Largo Resort. Exceptional staff and resort amenities. Beautiful beach and Key Largo property. Definitely coming back!" ![United States](https://a.travel-assets.com/egds/marks/flags/us.svg) Debra CA $547 CA $691 total includes taxes & fees Apr 12 - Apr 13 [](https://www.expedia.ca/Key-Largo-Hotels-Playa-Largo-Resort-Spa.h11919055.Hotel-Information) ![Single Room | Terrace/patio](https://images.trvl-media.com/lodging/75000000/74510000/74501700/74501641/ba4e7679.jpg?impolicy=fcrop&w=357&h=201&p=1&q=medium) ![Exterior](https://images.trvl-media.com/lodging/75000000/74510000/74501700/74501641/eb1153a6.jpg?impolicy=fcrop&w=357&h=201&p=1&q=medium) ![Exterior](https://images.trvl-media.com/lodging/75000000/74510000/74501700/74501641/c0f429ca.jpg?impolicy=fcrop&w=357&h=201&p=1&q=medium) ![Exterior](https://images.trvl-media.com/lodging/75000000/74510000/74501700/74501641/c2f29c15.jpg?impolicy=fcrop&w=357&h=201&p=1&q=medium) ### Kona Kai Resort and Gallery - Adults Only [](https://www.expedia.ca/Key-Largo-Hotels-Kona-Kai-Resort-And-Gallery.h74501641.Hotel-Information) Rock Harbor 9.8/10 Exceptional (305 reviews) "Very clean room and property staff very friendly and accommodating " ![United States](https://a.travel-assets.com/egds/marks/flags/us.svg) Jeffrey CA $431 CA $523 total includes taxes & fees Mar 17 - Mar 18 [](https://www.expedia.ca/Key-Largo-Hotels-Kona-Kai-Resort-And-Gallery.h74501641.Hotel-Information) ![In-room dining](https://images.trvl-media.com/lodging/109000000/108750000/108743400/108743380/c244835e.jpg?impolicy=fcrop&w=357&h=201&p=1&q=medium) ![Exterior](https://images.trvl-media.com/lodging/109000000/108750000/108743400/108743380/ab2c2d1e.jpg?impolicy=fcrop&w=357&h=201&p=1&q=medium) ![55-inch Smart TV with digital channels, books](https://images.trvl-media.com/lodging/109000000/108750000/108743400/108743380/96d842c8.jpg?impolicy=fcrop&w=357&h=201&p=1&q=medium) ![1 bedroom, premium bedding, individually furnished, blackout drapes](https://images.trvl-media.com/lodging/109000000/108750000/108743400/108743380/dc4f4949.jpg?impolicy=fcrop&w=357&h=201&p=1&q=medium) ### Premium Floating Bungalow by Stay Ombi [](https://www.expedia.ca/Key-Largo-Hotels-Premium-Floating-Bungalow-By-Stay-Ombi.h108743380.Hotel-Information) Key Largo 10/10 Exceptional (1 review) CA $1,499 CA $1,686 total includes taxes & fees Mar 17 - Mar 18 [](https://www.expedia.ca/Key-Largo-Hotels-Premium-Floating-Bungalow-By-Stay-Ombi.h108743380.Hotel-Information) ![Deep-tissue massages, Swedish massages, prenatal massages, massages](https://images.trvl-media.com/lodging/55000000/54780000/54774300/54774228/3064d810.jpg?impolicy=fcrop&w=357&h=201&p=1&q=medium) ![On the beach, sun loungers, beach umbrellas, beach towels](https://images.trvl-media.com/lodging/55000000/54780000/54774300/54774228/dd7d4fab.jpg?impolicy=fcrop&w=357&h=201&p=1&q=medium) ![Smart TV, Netflix, Hulu, streaming services](https://images.trvl-media.com/lodging/55000000/54780000/54774300/54774228/fcc01350.jpg?impolicy=fcrop&w=357&h=201&p=1&q=medium) ![Balcony view](https://images.trvl-media.com/lodging/55000000/54780000/54774300/54774228/95dbc957.jpg?impolicy=fcrop&w=357&h=201&p=1&q=medium) ### The Islands of Islamorada [](https://www.expedia.ca/Islamorada-Hotels-The-Islands-Of-Islamorada.h54774228.Hotel-Information) Matecumbe 9.8/10 Exceptional (72 reviews) "Beautiful accommodations and location, very clean, many activities available at resort" ![United States](https://a.travel-assets.com/egds/marks/flags/us.svg) Janet CA $959 CA $1,154 total includes taxes & fees Apr 13 - Apr 14 [](https://www.expedia.ca/Islamorada-Hotels-The-Islands-Of-Islamorada.h54774228.Hotel-Information) Lowest nightly price found within the past 24 hours based on a 1 night stay for 2 adults. Prices and availability subject to change. Additional terms may apply. [View all properties](https://expedia.ca/Hotel-Search?startDate=2026-03-30&endDate=2026-03-31®ionId=553248635083898347&adults=2&amenities=SPA_ON_SITE&sort=RECOMMENDED&openPlayBack=true) ## Choose what matters most at spa hotels in Plantation Key Pool Breakfast included Hot tub 4 stars 5 stars ## Find out more about Plantation Key ### Top Plantation Key attractions for a relaxing vacation Plantation Key offers a tranquil escape for those seeking both adventure and relaxation, making it an excellent choice for travellers looking to indulge in spa hotels. Begin your day at the beautiful Founders Park, where families can enjoy a sandy beach, picnic areas, and a calm water lagoon perfect for a refreshing swim. Nature enthusiasts will appreciate the nearby Florida Keys Wild Bird Rehabilitation Centre, where you can get up close with native bird species and learn about conservation efforts. For a unique experience, explore the underwater world at John Pennekamp Coral Reef State Park, where snorkelling and diving unveil vibrant coral reefs filled with marine life. After a day of exploration, unwind at one of the luxurious spa resorts in the area, such as the stunning Isla Bella Beach Resort, which offers soothing treatments and stunning ocean views. Plantation Key's charming atmosphere combined with top hotels ensures that your family can enjoy both adventure and pampering in one idyllic locale. ## Top Plantation Key Hotel Reviews ![Marina Del Mar Resort and Marina](https://images.trvl-media.com/lodging/1000000/10000/5200/5114/c05305d4_y.jpg) ### Marina Del Mar Resort and Marina 10/10 Excellent "Room was adequate in size and cleanliness. A little worn but perfectly adequate for a Florida vacation. Limited parking but nearby overflow. Resort in the more active part of town-shops, hotels, restaurants, tours, etc." [](https://expedia.ca/Key-Largo-Hotels-Marina-Del-Mar-Resort-And-Marina.h5114.Hotel-Information) ![Reefhouse Resort & Marina](https://images.trvl-media.com/lodging/1000000/10000/3500/3427/e9f2dff3_y.jpg) ### Reefhouse Resort & Marina 10/10 Excellent "Great parking, room service, clean etc. great service at pool and beach, food, towels, seating and shade if needed! " [](https://expedia.ca/Key-Largo-Hotels-Reefhouse-Resort-Marina.h3427.Hotel-Information) ![Amara Cay Resort](https://images.trvl-media.com/lodging/1000000/70000/62000/61976/4186365f_y.jpg) ### Amara Cay Resort 8/10 Good "Pool and beach area were extremely nice. The room was nice and clean, but you can tell it was an older hotel that they are working on remodeling. In some areas you could tell there was some deferred maintenance." [](https://expedia.ca/Islamorada-Hotels-Amara-Cay-Resort.h61976.Hotel-Information) ![Playa Largo Resort & Spa, Autograph Collection](https://images.trvl-media.com/lodging/12000000/11920000/11919100/11919055/8c74658c_y.jpg) ### Playa Largo Resort & Spa, Autograph Collection 8/10 Good "Overall wonderful resort and great location. " [](https://expedia.ca/Key-Largo-Hotels-Playa-Largo-Resort-Spa.h11919055.Hotel-Information) ![Baker's Cay Resort Key Largo, Curio Collection by Hilton](https://images.trvl-media.com/lodging/1000000/20000/14100/14042/7c755dc1_y.jpg) ### Baker's Cay Resort Key Largo, Curio Collection by Hilton 4/10 Poor "This hotel should be called Kids Camp. Pretty much all parents with young kids. Not recommended for couples wanting a romantic getaway. The check in staff were extremely unhelpful and each one told you something different. Had to wait 21/2 hours for our room. Food was mediocre at best. Compared to other Hilton resorts this is a disgrace." [](https://expedia.ca/Key-Largo-Hotels-Bakers-Cay-Resort-Key-Largo.h14042.Hotel-Information) ![Islander Resort](https://images.trvl-media.com/lodging/1000000/480000/475500/475438/f8d2863e_y.jpg) ### Islander Resort 8/10 Good "The private patio for each room was great perk. Loved the tropical vibe. The food was expensive." [](https://expedia.ca/Islamorada-Hotels-Islander-Resort.h475438.Hotel-Information) ![Chesapeake Beach Resort](https://images.trvl-media.com/lodging/1000000/10000/4200/4170/689f4306_y.jpg) ### Chesapeake Beach Resort 6/10 Okay "Staff wasn’t very helpful or accommodating. " [](https://expedia.ca/Islamorada-Hotels-Chesapeake-Beach-Resort.h4170.Hotel-Information) ![Holiday Inn Key Largo by IHG](https://images.trvl-media.com/lodging/1000000/10000/7300/7230/855a0cf4_y.jpg) ### Holiday Inn Key Largo by IHG 10/10 Excellent "Excelent hotel. Beautiful pool, delicious buffet breakfast, gym 24 hours and all very complete. I love this hotel and I would definitely go back❤️🌅👍" [](https://expedia.ca/Key-Largo-Hotels-Holiday-Inn-Key-Largo.h7230.Hotel-Information) ![Lime Tree Bay Resort](https://images.trvl-media.com/lodging/1000000/890000/882300/882254/55bf0b8b_y.jpg) ### Lime Tree Bay Resort 10/10 Excellent "We loved staying here! We had a great ocean view and the property was beautiful. We just wish we could have stayed longer!" 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