Title: Book the Best BUSINESS Hotels in Piketon in 2026 | Expedia.ca [Hotels in Piketon](https://expedia.ca/Piketon-Hotels.d55902.Travel-Guide-Hotels)[Vacation Rentals in Piketon](https://expedia.ca/Piketon-Vacation-Rentals.d55902.Travel-Guide-VacationRentals)[Piketon Car Rentals](https://expedia.ca/Car-Rentals-In-Piketon.d55902.Car-Rental-Guide)[Piketon Vacation Packages](https://expedia.ca/Piketon.d55902.Destination-Travel-Guides) ![a creepy old abandoned house near the "welcome to piketon" sign on the edge of scioto county. i found syringes in her the last time i visited. ](https://images.trvl-media.com/place/55902/eff0fa2a-2463-48da-8eff-7c754d3c0d4b.jpg?impolicy=fcrop&w=1200&h=500&q=medium) Photo by rikki cornett ![](https://images.trvl-media.com/place/55902/eff0fa2a-2463-48da-8eff-7c754d3c0d4b.jpg?impolicy=fcrop&w=1200&h=500&q=medium) - ![](https://a.travel-assets.com/travel-assets-manager/pictogram-bex/light__calendar_shield.svg) ### Change your mind Book hotels with free cancellation - ![](https://a.travel-assets.com/travel-assets-manager/pictogram-bex/light__deals.svg) ### Treat yourself Sign in to save 10% or more on thousands of hotels [Sign in](https://www.expedia.ca/login) - ![](https://a.travel-assets.com/travel-assets-manager/pictogram-bex/light__bed.svg) ### Be picky Search almost a million properties worldwide ## Check availability on Piketon Business Hotels Tonight [Jan 31 - Feb 1](https://www.expedia.ca/Hotel-Search?regionId=55902&startDate=2026-01-31&endDate=2026-02-01&adults=2&rfrr=TG.LP.CheckPrices.Hotel&openPlayBack=true&travelerType=business_friendly) Tomorrow [Feb 1 - Feb 2](https://www.expedia.ca/Hotel-Search?regionId=55902&startDate=2026-02-01&endDate=2026-02-02&adults=2&rfrr=TG.LP.CheckPrices.Hotel&openPlayBack=true&travelerType=business_friendly) Next weekend [Feb 6 - Feb 8](https://www.expedia.ca/Hotel-Search?regionId=55902&startDate=2026-02-06&endDate=2026-02-08&adults=2&rfrr=TG.LP.CheckPrices.Hotel&openPlayBack=true&travelerType=business_friendly) In two weeks [Feb 13 - Feb 15](https://www.expedia.ca/Hotel-Search?regionId=55902&startDate=2026-02-13&endDate=2026-02-15&adults=2&rfrr=TG.LP.CheckPrices.Hotel&openPlayBack=true&travelerType=business_friendly) ## Our top choices for Piketon business-friendly hotels ![Down comforters, desk, blackout drapes, iron/ironing board](https://images.trvl-media.com/lodging/1000000/20000/13000/12951/7112d0ea.jpg?impolicy=fcrop&w=357&h=201&p=1&q=medium) ![Lobby](https://images.trvl-media.com/lodging/1000000/20000/13000/12951/75f74fcd.jpg?impolicy=fcrop&w=357&h=201&p=1&q=medium) ![Free daily continental breakfast](https://images.trvl-media.com/lodging/1000000/20000/13000/12951/2f1d0964.jpg?impolicy=fcrop&w=357&h=201&p=1&q=medium) ![Lobby](https://images.trvl-media.com/lodging/1000000/20000/13000/12951/a9e2d37d.jpg?impolicy=fcrop&w=357&h=201&p=1&q=medium) ### Comfort Inn Piketon near Fairgrounds [](https://www.expedia.ca/Chillicothe-Hotels-Comfort-Inn.h12951.Hotel-Information) Piketon 8.2/10 Very good (370 reviews) "Nice hotel and area." ![United States](https://a.travel-assets.com/egds/marks/flags/us.svg) Shannon CA $128 CA $145 total includes taxes & fees Mar 3 - Mar 4 [](https://www.expedia.ca/Chillicothe-Hotels-Comfort-Inn.h12951.Hotel-Information) ![Gym](https://images.trvl-media.com/lodging/1000000/40000/34200/34164/fcecac02.jpg?impolicy=fcrop&w=357&h=201&p=1&q=medium) ![Desk, laptop workspace, soundproofing, iron/ironing board](https://images.trvl-media.com/lodging/1000000/40000/34200/34164/e2ea5317.jpg?impolicy=fcrop&w=357&h=201&p=1&q=medium) ![Free daily buffet breakfast](https://images.trvl-media.com/lodging/1000000/40000/34200/34164/d5461db3.jpg?impolicy=fcrop&w=357&h=201&p=1&q=medium) ![Suite, 1 King Bed, Jetted Tub | Jetted tub](https://images.trvl-media.com/lodging/1000000/40000/34200/34164/3d76b172.jpg?impolicy=fcrop&w=357&h=201&p=1&q=medium) ### Quality Inn Wheelersburg [](https://www.expedia.ca/Portsmouth-Hotels-Quality-Inn.h34164.Hotel-Information) Wheelersburg 8.2/10 Very good (322 reviews) "Staff was great very friendly. Room was very clean and Breakfast bar was great" ![United States](https://a.travel-assets.com/egds/marks/flags/us.svg) Eric CA $126 CA $140 total includes taxes & fees Feb 2 - Feb 3 [](https://www.expedia.ca/Portsmouth-Hotels-Quality-Inn.h34164.Hotel-Information) ![Indoor pool](https://images.trvl-media.com/lodging/2000000/1040000/1039700/1039674/1af2e54b.jpg?impolicy=fcrop&w=357&h=201&p=1&q=medium) ![Indoor spa tub](https://images.trvl-media.com/lodging/2000000/1040000/1039700/1039674/e5a50225.jpg?impolicy=fcrop&w=357&h=201&p=1&q=medium) ![Corporate Suite](https://images.trvl-media.com/lodging/2000000/1040000/1039700/1039674/f7589ecf.jpg?impolicy=fcrop&w=357&h=201&p=1&q=medium) ![Lobby sitting area](https://images.trvl-media.com/lodging/2000000/1040000/1039700/1039674/fb22d150.jpg?impolicy=fcrop&w=357&h=201&p=1&q=medium) ### Christopher Inn and Suites [](https://www.expedia.ca/Chillicothe-Hotels-Christopher-Inn-And-Suites.h1039674.Hotel-Information) Chillicothe 9.0/10 Wonderful (1,155 reviews) "Staff was nice. Place was clean. Would stay here again. " ![United States](https://a.travel-assets.com/egds/marks/flags/us.svg) Mark CA $169 CA $194 total includes taxes & fees Feb 15 - Feb 16 [](https://www.expedia.ca/Chillicothe-Hotels-Christopher-Inn-And-Suites.h1039674.Hotel-Information) ![Exterior](https://images.trvl-media.com/lodging/1000000/120000/116700/116614/231554a3.jpg?impolicy=fcrop&w=357&h=201&p=1&q=medium) ![Suite, 1 King Bed](https://images.trvl-media.com/lodging/1000000/120000/116700/116614/63c18cc1.jpg?impolicy=fcrop&w=357&h=201&p=1&q=medium) ![Exterior](https://images.trvl-media.com/lodging/1000000/120000/116700/116614/3384af32.jpg?impolicy=fcrop&w=357&h=201&p=1&q=medium) ![Indoor pool](https://images.trvl-media.com/lodging/1000000/120000/116700/116614/e8213eeb.jpg?impolicy=fcrop&w=357&h=201&p=1&q=medium) ### Holiday Inn Express Chillicothe East by IHG [](https://www.expedia.ca/Chillicothe-Hotels-Holiday-Inn-Express-Chillicothe-East.h116614.Hotel-Information) Chillicothe 8.8/10 Excellent (843 reviews) "Room was clean and front desk staff at check in and check out were super friendly. Great guys!!" ![United States](https://a.travel-assets.com/egds/marks/flags/us.svg) Anthony CA $176 CA $201 total includes taxes & fees Feb 15 - Feb 16 [](https://www.expedia.ca/Chillicothe-Hotels-Holiday-Inn-Express-Chillicothe-East.h116614.Hotel-Information) ![Interior](https://images.trvl-media.com/lodging/1000000/30000/26900/26889/42788093.jpg?impolicy=fcrop&w=357&h=201&p=1&q=medium) ![Hallway](https://images.trvl-media.com/lodging/1000000/30000/26900/26889/8dd0bb49.jpg?impolicy=fcrop&w=357&h=201&p=1&q=medium) ![Interior](https://images.trvl-media.com/lodging/1000000/30000/26900/26889/351d1a45.jpg?impolicy=fcrop&w=357&h=201&p=1&q=medium) ![Room, 2 Double Beds, Non Smoking](https://images.trvl-media.com/lodging/1000000/30000/26900/26889/31b4bb37.jpg?impolicy=fcrop&w=357&h=201&p=1&q=medium) ### Days Inn by Wyndham Jackson [](https://www.expedia.ca/Chillicothe-Hotels-Days-Inn-By-Wyndham-Jackson.h26889.Hotel-Information) Jackson 7.4/10 Good (380 reviews) "Food was fresh, staff was very nice" ![United States](https://a.travel-assets.com/egds/marks/flags/us.svg) Philip CA $117 CA $136 total includes taxes & fees Mar 1 - Mar 2 [](https://www.expedia.ca/Chillicothe-Hotels-Days-Inn-By-Wyndham-Jackson.h26889.Hotel-Information) ![Suite, 1 King Bed, Non Smoking](https://images.trvl-media.com/lodging/1000000/40000/39900/39801/ffe2e28d.jpg?impolicy=fcrop&w=357&h=201&p=1&q=medium) ![Free daily full breakfast](https://images.trvl-media.com/lodging/1000000/40000/39900/39801/1748f59e.jpg?impolicy=fcrop&w=357&h=201&p=1&q=medium) ![Lobby](https://images.trvl-media.com/lodging/1000000/40000/39900/39801/14e9f241.jpg?impolicy=fcrop&w=357&h=201&p=1&q=medium) ![Indoor pool](https://images.trvl-media.com/lodging/1000000/40000/39900/39801/90787c22.jpg?impolicy=fcrop&w=357&h=201&p=1&q=medium) ### Super 8 by Wyndham Portsmouth [](https://www.expedia.ca/Portsmouth-Hotels-Super-8-By-Wyndham-Portsmouth.h39801.Hotel-Information) Portsmouth 7.0/10 Good (697 reviews) "it was clean and comfortable.,nice stay" ![United States](https://a.travel-assets.com/egds/marks/flags/us.svg) Patricia CA $103 CA $115 total includes taxes & fees Feb 8 - Feb 9 [](https://www.expedia.ca/Portsmouth-Hotels-Super-8-By-Wyndham-Portsmouth.h39801.Hotel-Information) ![Free daily continental breakfast](https://images.trvl-media.com/lodging/1000000/30000/27200/27143/w2880h2160x0y1-7e953889.jpg?impolicy=fcrop&w=357&h=201&p=1&q=medium) ![Exterior](https://images.trvl-media.com/lodging/1000000/30000/27200/27143/w2880h2595x0y12-728a117f.jpg?impolicy=fcrop&w=357&h=201&p=1&q=medium) ![Desk, iron/ironing board, free cribs/infant beds, free WiFi](https://images.trvl-media.com/lodging/1000000/30000/27200/27143/b6a3b6c0.jpg?impolicy=fcrop&w=357&h=201&p=1&q=medium) ![Concierge desk](https://images.trvl-media.com/lodging/1000000/30000/27200/27143/a88a036b.jpg?impolicy=fcrop&w=357&h=201&p=1&q=medium) ### Red Roof Inn Wheelersburg [](https://www.expedia.ca/Portsmouth-Hotels-Red-Roof-Inn-Portsmouth-Wheelersburg.h27143.Hotel-Information) Wheelersburg 7.0/10 Good (296 reviews) "Staff was very nice and polite" ![United States](https://a.travel-assets.com/egds/marks/flags/us.svg) Dylan [](https://www.expedia.ca/Portsmouth-Hotels-Red-Roof-Inn-Portsmouth-Wheelersburg.h27143.Hotel-Information) ![Standard Suite, 1 King Bed](https://images.trvl-media.com/lodging/1000000/910000/907700/907621/0567ca62.jpg?impolicy=fcrop&w=357&h=201&p=1&q=medium) ![Combined shower/tub, hair dryer, towels](https://images.trvl-media.com/lodging/1000000/910000/907700/907621/87625974.jpg?impolicy=fcrop&w=357&h=201&p=1&q=medium) ![Standard Suite, 1 King Bed](https://images.trvl-media.com/lodging/1000000/910000/907700/907621/36e10c8a.jpg?impolicy=fcrop&w=357&h=201&p=1&q=medium) ![Exterior](https://images.trvl-media.com/lodging/1000000/910000/907700/907621/d58a5d57.jpg?impolicy=fcrop&w=357&h=201&p=1&q=medium) ### Ameristay Hotel Inn & Suites Waverly [](https://www.expedia.ca/Chillicothe-Hotels-Ameristay-Hotel-Inn-Suites-Waverly.h907621.Hotel-Information) Waverly 7.4/10 Good (212 reviews) "The staff was very nice. " ![United States](https://a.travel-assets.com/egds/marks/flags/us.svg) Barbara CA $135 CA $149 total includes taxes & fees Mar 3 - Mar 4 [](https://www.expedia.ca/Chillicothe-Hotels-Ameristay-Hotel-Inn-Suites-Waverly.h907621.Hotel-Information) ![55-inch Smart TV with digital channels, Netflix, Hulu](https://images.trvl-media.com/lodging/96000000/95420000/95419500/95419468/cae7cead.jpg?impolicy=fcrop&w=357&h=201&p=1&q=medium) ![55-inch Smart TV with digital channels, Netflix, Hulu](https://images.trvl-media.com/lodging/96000000/95420000/95419500/95419468/ab3a83ed.jpg?impolicy=fcrop&w=357&h=201&p=1&q=medium) ![Egyptian cotton sheets, premium bedding, memory foam beds, free minibar](https://images.trvl-media.com/lodging/96000000/95420000/95419500/95419468/54ba9c5d.jpg?impolicy=fcrop&w=357&h=201&p=1&q=medium) ![Full-size fridge, microwave, oven, stovetop](https://images.trvl-media.com/lodging/96000000/95420000/95419500/95419468/cbedfebf.jpg?impolicy=fcrop&w=357&h=201&p=1&q=medium) ### Jungle House Luxury Stays - Downtown Chillicothe [](https://www.expedia.ca/Chillicothe-Hotels-Jungle-Thyme.h95419468.Hotel-Information) Chillicothe 9.8/10 Exceptional (8 reviews) "Great location, great atmosphere, and lots of space" ![United States](https://a.travel-assets.com/egds/marks/flags/us.svg) Tammy [](https://www.expedia.ca/Chillicothe-Hotels-Jungle-Thyme.h95419468.Hotel-Information) ![Desk, laptop workspace, iron/ironing board, WiFi](https://images.trvl-media.com/lodging/1000000/10000/8600/8583/77e26219.jpg?impolicy=fcrop&w=357&h=201&p=1&q=medium) ![Suite, 1 King Bed, Non Smoking, Jetted Tub](https://images.trvl-media.com/lodging/1000000/10000/8600/8583/256c1e6a.jpg?impolicy=fcrop&w=357&h=201&p=1&q=medium) ![Exterior](https://images.trvl-media.com/lodging/1000000/10000/8600/8583/60c334e7.jpg?impolicy=fcrop&w=357&h=201&p=1&q=medium) ![Free daily buffet breakfast](https://images.trvl-media.com/lodging/1000000/10000/8600/8583/8b407aef.jpg?impolicy=fcrop&w=357&h=201&p=1&q=medium) ### Best Western Adena Inn [](https://www.expedia.ca/Chillicothe-Hotels-Best-Western-Adena-Inn.h8583.Hotel-Information) Chillicothe 7.8/10 Good (785 reviews) "The room was very clean and the staff was great. The continental breakfast was very good with a lot of variety. " ![United States](https://a.travel-assets.com/egds/marks/flags/us.svg) Virginia CA $163 CA $187 total includes taxes & fees Feb 1 - Feb 2 [](https://www.expedia.ca/Chillicothe-Hotels-Best-Western-Adena-Inn.h8583.Hotel-Information) Lowest nightly price found within the past 24 hours based on a 1 night stay for 2 adults. Prices and availability subject to change. Additional terms may apply. [View all properties](https://expedia.ca/Hotel-Search?startDate=2026-02-14&endDate=2026-02-15®ionId=55902&adults=2&travelerType=business_friendly&sort=RECOMMENDED&openPlayBack=true) ## Top Piketon Hotel Reviews ![Christopher Inn and Suites](https://images.trvl-media.com/lodging/2000000/1040000/1039700/1039674/50c4cecb_y.jpg) ### Christopher Inn and Suites 10/10 Excellent "Great staff, very friendly and helpful. Amazing swimming pool and room was big and comfortable" [](https://expedia.ca/Chillicothe-Hotels-Christopher-Inn-And-Suites.h1039674.Hotel-Information) ![Holiday Inn Express Chillicothe East by IHG](https://images.trvl-media.com/lodging/1000000/120000/116700/116614/5fe8d2c6_y.jpg) ### Holiday Inn Express Chillicothe East by IHG 10/10 Excellent "Clean, quiet room. Friendly staff. Perfect for our one night stay. " [](https://expedia.ca/Chillicothe-Hotels-Holiday-Inn-Express-Chillicothe-East.h116614.Hotel-Information) ![Super 8 by Wyndham Portsmouth](https://images.trvl-media.com/lodging/1000000/40000/39900/39801/2623add7_y.jpg) ### Super 8 by Wyndham Portsmouth 10/10 Excellent "The room was clean, most comfortable bed, we loved the hot tub in the room, and the staff was the ABSOLUTE BEST! We will stay here again!" [](https://expedia.ca/Portsmouth-Hotels-Super-8-By-Wyndham-Portsmouth.h39801.Hotel-Information) ![Quality Inn](https://images.trvl-media.com/lodging/1000000/20000/14700/14647/6a921f8c_y.jpg) ### Quality Inn 10/10 Excellent "the room was clean, the shower was amazing with a strong water flow. They accommodated our request for a first floor room. I have no complaints." [](https://expedia.ca/Chillicothe-Hotels-Quality-Inn.h14647.Hotel-Information) ![Red Roof Inn Jackson, OH](https://images.trvl-media.com/lodging/1000000/920000/911900/911869/dc72906a_y.jpg) ### Red Roof Inn Jackson, OH 10/10 Excellent "Very clean Comfy room!" [](https://expedia.ca/Chillicothe-Hotels-Red-Roof-Inn-Jackson.h911869.Hotel-Information) ![Best Western Adena Inn](https://images.trvl-media.com/lodging/1000000/10000/8600/8583/9618bbe6_y.jpg) ### Best Western Adena Inn 10/10 Excellent "Clean and comfortable. Slept through the entire night, which don’t happen too often. " [](https://expedia.ca/Chillicothe-Hotels-Best-Western-Adena-Inn.h8583.Hotel-Information) ![Holiday Inn Portsmouth Downtown by IHG](https://images.trvl-media.com/lodging/1000000/30000/20500/20403/42ca14f7_y.jpg) ### Holiday Inn Portsmouth Downtown by IHG 10/10 Excellent "The hotel was clean with easy access to Shawnee State University. " [](https://expedia.ca/Portsmouth-Hotels-Holiday-Inn-Portsmouth-Downtown.h20403.Hotel-Information) ![Quality Inn Chillicothe](https://images.trvl-media.com/lodging/1000000/20000/11100/11077/32019329_y.jpg) ### Quality Inn Chillicothe 10/10 Excellent "Clean rooms| Dog friendly|Bar|Staff|Right next to highway" [](https://expedia.ca/Chillicothe-Hotels-Quality-Inn.h11077.Hotel-Information) ![Quality Inn](https://images.trvl-media.com/lodging/1000000/40000/34200/34164/4670d89c_y.jpg) ### Quality Inn 10/10 Excellent "Friendly staff. Clean and very quiet rooms. Very comfortable beds. Everything that you need in a hotel room at a good price point. Would definitely stay here again. " [](https://expedia.ca/Portsmouth-Hotels-Quality-Inn.h34164.Hotel-Information) ## Frequently asked questions ### How much do business-friendly hotels in Piketon cost? ### What are the best business-friendly hotels in Piketon? ### How many business-friendly hotels are there in Piketon? ### What are the best cheap business-friendly hotels in Piketon? ### Are there any family-friendly hotels in Piketon that are also business friendly? ### Why book your business-friendly hotel in Piketon with Expedia? ### How can I find cheap business-friendly hotels in Piketon? ### What is there to do in Piketon near my business-friendly hotel? ## Explore a world of travel with Expedia - Lodging - Flights - Packages - Cars - More ways to book - [5 Star Hotels in Peebles ](https://www.expedia.ca/5Star-Peebles-Hotels.s50-0-d6195740.Travel-Guide-Filter-Hotels) - [Farmstay in Bainbridge ](https://www.expedia.ca/Bainbridge-Agritourism.d3000452274-aaAgritourism.Travel-Guide-Accommodation) - [B&B in Bainbridge ](https://www.expedia.ca/Bainbridge-Bed-And-Breakfast.d3000452274-aaBedAndBreakfast.Travel-Guide-Accommodation) - 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