Title: Book the Best Pico-Union LUXURY Hotels - Upscale Hotels in Pico-Union, Los Angeles | Expedia.ca [Vacation Rentals in Los Angeles](https://expedia.ca/Los-Angeles-Vacation-Rentals.d178280.Travel-Guide-VacationRentals)[Flights to Los Angeles](https://expedia.ca/Cheap-Flights-To-Los-Angeles.d178280.Travel-Guide-Flights)[Things to do in Los Angeles](https://expedia.ca/Things-To-Do-In-Los-Angeles.d178280.Travel-Guide-Activities)[Pico-Union Car Rentals](https://expedia.ca/Car-Rentals-In-Pico-Union.d553248635976469609.Car-Rental-Guide)[Pico-Union Vacations](https://expedia.ca/Pico-Union.d553248635976469609.Destination-Travel-Guides) ![Default HTG hotel image](https://a.travel-assets.com/travel-assets-manager/bex-affinities/luxury.jpeg?impolicy=fcrop&w=1200&h=500&q=medium) ![](https://a.travel-assets.com/travel-assets-manager/bex-affinities/luxury.jpeg?impolicy=fcrop&w=1200&h=500&q=medium) - ![](https://a.travel-assets.com/travel-assets-manager/pictogram-bex/light__calendar_shield.svg) ### Change your mind Book hotels with free cancellation - ![](https://a.travel-assets.com/travel-assets-manager/pictogram-bex/light__deals.svg) ### Treat yourself Sign in to save 10% or more on thousands of hotels [Sign in](https://www.expedia.ca/login) - ![](https://a.travel-assets.com/travel-assets-manager/pictogram-bex/light__bed.svg) ### Be picky Search almost a million properties worldwide ## Check availability on Pico-Union Luxury Hotels Tonight [Jan 27 - Jan 28](https://www.expedia.ca/Hotel-Search?regionId=553248635976469609&startDate=2026-01-27&endDate=2026-01-28&adults=2&propertyStyle=LUXURY&rfrr=TG.LP.CheckPrices.Hotel&openPlayBack=true&travelerType=luxury_property) Tomorrow [Jan 28 - Jan 29](https://www.expedia.ca/Hotel-Search?regionId=553248635976469609&startDate=2026-01-28&endDate=2026-01-29&adults=2&propertyStyle=LUXURY&rfrr=TG.LP.CheckPrices.Hotel&openPlayBack=true&travelerType=luxury_property) This weekend [Jan 30 - Feb 1](https://www.expedia.ca/Hotel-Search?regionId=553248635976469609&startDate=2026-01-30&endDate=2026-02-01&adults=2&propertyStyle=LUXURY&rfrr=TG.LP.CheckPrices.Hotel&openPlayBack=true&travelerType=luxury_property) Next weekend [Feb 6 - Feb 8](https://www.expedia.ca/Hotel-Search?regionId=553248635976469609&startDate=2026-02-06&endDate=2026-02-08&adults=2&propertyStyle=LUXURY&rfrr=TG.LP.CheckPrices.Hotel&openPlayBack=true&travelerType=luxury_property) ## Top Pico-Union Hotel Reviews ![Biltmore Los Angeles](https://images.trvl-media.com/lodging/1000000/30000/25800/25715/7a2f57ed_y.jpg) ### Biltmore Los Angeles 10/10 Excellent "Yed" [](https://expedia.ca/Los-Angeles-Hotels-Millennium-Biltmore-Los-Angeles.h25715.Hotel-Information) ![Motel 6 Los Angeles, CA - Los Angeles - LAX](https://images.trvl-media.com/lodging/1000000/50000/50000/49971/e320f0a7_y.jpg) ### Motel 6 Los Angeles, CA - Los Angeles - LAX 10/10 Excellent "nice place to stay." [](https://expedia.ca/Los-Angeles-Hotels-Motel-6-Los-Angeles.h49971.Hotel-Information) ![E-Central Downtown Los Angeles Hotel](https://images.trvl-media.com/lodging/1000000/10000/4000/3952/f573b858_y.jpg) ### E-Central Downtown Los Angeles Hotel 10/10 Excellent "the room was spotless and the hotel was exactly where we wanted to be as far as walking distance to the arena and restaurants. Staff was very helpful with all the questions we had. Would stay there again." [](https://expedia.ca/Los-Angeles-Hotels-E-Central-Downtown-Los-Angeles-Hotel.h3952.Hotel-Information) ![Hyatt Regency Los Angeles International Airport](https://images.trvl-media.com/lodging/1000000/20000/15500/15407/8ded1a41_y.jpg) ### Hyatt Regency Los Angeles International Airport 10/10 Excellent "Perfect location for LAX. Nicelt appointed room, the gym equipment in the fitness centre is well above average for a hotel set up. Very impressed. " [](https://expedia.ca/Los-Angeles-Hotels-Hyatt-Regency-Los-Angeles-International-Airport.h15407.Hotel-Information) ![Hilton Los Angeles Airport](https://images.trvl-media.com/lodging/1000000/10000/6000/5907/ac835d76_y.jpg) ### Hilton Los Angeles Airport 10/10 Excellent "The room was excellent. Despite being near the airport, it was very quiet. Thr shuttle to the airport is convenient and reliable. The staff was exceptionally courteous. " [](https://expedia.ca/Los-Angeles-Hotels-Hilton-Los-Angeles-Airport.h5907.Hotel-Information) ![Sheraton Gateway Los Angeles Hotel](https://images.trvl-media.com/lodging/1000000/20000/12300/12287/ad991023_y.jpg) ### Sheraton Gateway Los Angeles Hotel 10/10 Excellent "No complaints everything was great" [](https://expedia.ca/Los-Angeles-Hotels-Sheraton-Gateway-Los-Angeles-Hotel.h12287.Hotel-Information) ![Hotel Burbank](https://images.trvl-media.com/lodging/1000000/10000/7500/7457/7ff5ade4_y.jpg) ### Hotel Burbank 10/10 Excellent "Well located and priced hotel for a quick overnight near Burbank airport. Friendly staff and comfortable rooms with a great view from high floors and the elevator" [](https://expedia.ca/Los-Angeles-Hotels-Hotel-Burbank.h7457.Hotel-Information) ![DoubleTree by Hilton LAX - El Segundo](https://images.trvl-media.com/lodging/1000000/20000/16500/16424/2af6c0a4_y.jpg) ### DoubleTree by Hilton LAX - El Segundo 10/10 Excellent "All good" [](https://expedia.ca/Los-Angeles-Hotels-DoubleTree-By-Hilton-LAX-El-Segundo.h16424.Hotel-Information) ![Loews Hollywood Hotel](https://images.trvl-media.com/lodging/1000000/800000/790200/790158/70ab290b_y.jpg) ### Loews Hollywood Hotel 10/10 Excellent "Wonderful place, lovely people and amazing location. " [](https://expedia.ca/Los-Angeles-Hotels-Loews-Hollywood-Hotel.h790158.Hotel-Information) ## Frequently asked questions ### Are you searching for a great accommodation for your luxury trip to Pico-Union? ### What's there to see and do in Pico-Union? ## Explore a world of travel with Expedia - Lodging - More ways to book - [Honeymoon Resorts and in Beverly Hills ](https://www.expedia.ca/Beverly-Hills-Hotels-Honeymoon-Hotels.0-0-d6912-tHoneymoonHotels.Travel-Guide-Filter-Hotels) - [Mountain Hotels in Beverly Hills ](https://www.expedia.ca/Beverly-Hills-Hotels-Mountain-Hotels.0-0-d6912-tMountainHotels.Travel-Guide-Filter-Hotels) - [Winery Hotels in Beverly Hills ](https://www.expedia.ca/Beverly-Hills-Hotels-Winery-Hotel.0-0-d6912-tWineryHotel.Travel-Guide-Filter-Hotels) - [Hotels & Resorts for Couples in Los Angeles County ](https://www.expedia.ca/Destinations-In-Los-Angeles-County-Couples-Resorts-Hotels.0-0-d6056560-tCouplesResortsHotels.Hotel-Filter-Destinations) - [Hotels with a Pool in Los Angeles County ](https://www.expedia.ca/Destinations-In-Los-Angeles-County-Hotel-With-Pool.0-0-d6056560-tHotelwithPool.Hotel-Filter-Destinations) - 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