Title: Book the Best BUSINESS Hotels in Picayune in 2025 | Expedia.ca [Hotels in Picayune](https://expedia.ca/Picayune-Hotels.d9372.Travel-Guide-Hotels)[Vacation Rentals in Picayune](https://expedia.ca/Picayune-Vacation-Rentals.d9372.Travel-Guide-VacationRentals)[Flights to Picayune](https://expedia.ca/Cheap-Flights-To-Picayune.d9372.Travel-Guide-Flights)[Picayune Car Rentals](https://expedia.ca/Car-Rentals-In-Picayune.d9372.Car-Rental-Guide)[Picayune Vacation Packages](https://expedia.ca/Picayune.d9372.Destination-Travel-Guides) ![Default HTG hotel image](https://media.expedia.com/media/content/shared/images/travelguides/sem-hotels-tablet.jpg?impolicy=fcrop&w=1200&h=500&q=medium) # Find Business Hotels in Picayune, MS from CA $96 ![](https://a.travel-assets.com/travel-assets-manager/pictogram-bex/light__calendar_shield.svg) ### Change your mind Book hotels with free cancellation ![](https://a.travel-assets.com/travel-assets-manager/pictogram-bex/light__deals.svg) ### Treat yourself Sign in to save 10% or more on thousands of hotels [Sign in](https://www.expedia.ca/login) ![](https://a.travel-assets.com/travel-assets-manager/pictogram-bex/light__bed.svg) ### Be picky Search almost a million properties worldwide ## Check availability on Picayune Business Hotels Tonight [Oct 14 - Oct 15](https://www.expedia.ca/Hotel-Search?regionId=9372&startDate=2025-10-14&endDate=2025-10-15&adults=2&travelerType=BUSINESS&rfrr=TG.LP.CheckPrices.Hotel&openPlayBack=true) Tomorrow [Oct 15 - Oct 16](https://www.expedia.ca/Hotel-Search?regionId=9372&startDate=2025-10-15&endDate=2025-10-16&adults=2&travelerType=BUSINESS&rfrr=TG.LP.CheckPrices.Hotel&openPlayBack=true) This weekend [Oct 17 - Oct 19](https://www.expedia.ca/Hotel-Search?regionId=9372&startDate=2025-10-17&endDate=2025-10-19&adults=2&travelerType=BUSINESS&rfrr=TG.LP.CheckPrices.Hotel&openPlayBack=true) Next weekend [Oct 24 - Oct 26](https://www.expedia.ca/Hotel-Search?regionId=9372&startDate=2025-10-24&endDate=2025-10-26&adults=2&travelerType=BUSINESS&rfrr=TG.LP.CheckPrices.Hotel&openPlayBack=true) ## Top Picayune Business Hotels ![Exterior](https://images.trvl-media.com/lodging/3000000/2670000/2665100/2665063/f291f597.jpg?impolicy=fcrop&w=357&h=201&p=1&q=medium) ![Standard Room, 2 Queen Beds](https://images.trvl-media.com/lodging/3000000/2670000/2665100/2665063/f9378e98.jpg?impolicy=fcrop&w=357&h=201&p=1&q=medium) ![Fitness facility](https://images.trvl-media.com/lodging/3000000/2670000/2665100/2665063/53af01e9.jpg?impolicy=fcrop&w=357&h=201&p=1&q=medium) ![Free daily buffet breakfast](https://images.trvl-media.com/lodging/3000000/2670000/2665100/2665063/65070cae.jpg?impolicy=fcrop&w=357&h=201&p=1&q=medium) ### Holiday Inn Express Picayune-Stennis Space Center by IHG Picayune 9.0/10 Wonderful (624) "Everything was great" CA $134 CA $146 total includes taxes & fees Nov 4 - Nov 5 [](https://www.expedia.ca/Picayune-Hotels-Holiday-Inn-Express-Picayune-Stennis-Space-Center.h2665063.Hotel-Information) ![In-room safe, desk, iron/ironing board, free WiFi](https://images.trvl-media.com/lodging/2000000/1930000/1926200/1926144/521624b3.jpg?impolicy=fcrop&w=357&h=201&p=1&q=medium) ![Free daily on-the-go breakfast](https://images.trvl-media.com/lodging/2000000/1930000/1926200/1926144/43371e75.jpg?impolicy=fcrop&w=357&h=201&p=1&q=medium) ![Combined shower/tub, towels](https://images.trvl-media.com/lodging/2000000/1930000/1926200/1926144/92ca1b1d.jpg?impolicy=fcrop&w=357&h=201&p=1&q=medium) ![Check-in/check-out kiosk](https://images.trvl-media.com/lodging/2000000/1930000/1926200/1926144/966a4633.jpg?impolicy=fcrop&w=357&h=201&p=1&q=medium) ### Super 8 by Wyndham Picayune Picayune 6.6/10 (227) "The property was dated but clean and was a good value for the cost, overall. However, neighbors on both sides of us had a party in the parking lot with LOUD music and laughter until 11 pm 2 of the 3 nights of our stay. The bed was clean but most uncomfortable. We probably will choose another hotel for our next stay." CA $94 CA $103 total includes taxes & fees Oct 26 - Oct 27 [](https://www.expedia.ca/Picayune-Hotels-Super-8-By-Wyndham-Picayune.h1926144.Hotel-Information) ![Pool](https://images.trvl-media.com/lodging/1000000/70000/61100/61048/e69597e0.jpg?impolicy=fcrop&w=357&h=201&p=1&q=medium) ![Free daily on-the-go breakfast](https://images.trvl-media.com/lodging/1000000/70000/61100/61048/f94cd31a.jpg?impolicy=fcrop&w=357&h=201&p=1&q=medium) ![In-room safe, desk, iron/ironing board, free WiFi](https://images.trvl-media.com/lodging/1000000/70000/61100/61048/e3c21a96.jpg?impolicy=fcrop&w=357&h=201&p=1&q=medium) ![Lobby](https://images.trvl-media.com/lodging/1000000/70000/61100/61048/a638d545.jpg?impolicy=fcrop&w=357&h=201&p=1&q=medium) ### Econo Lodge Picayune Picayune 6.2/10 (134) "The staff was friendly and it was very quiet. The pool was not open and the room could really use updating." CA $98 CA $107 total includes taxes & fees Nov 13 - Nov 14 [](https://www.expedia.ca/Picayune-Hotels-Econo-Lodge-Picayune.h61048.Hotel-Information) ![Exterior](https://images.trvl-media.com/lodging/102000000/101540000/101532600/101532511/a50035f4.jpg?impolicy=fcrop&w=357&h=201&p=1&q=medium) ![Standard Room, 2 Double Beds, Non Smoking](https://images.trvl-media.com/lodging/102000000/101540000/101532600/101532511/40d2124b.jpg?impolicy=fcrop&w=357&h=201&p=1&q=medium) ![Exterior](https://images.trvl-media.com/lodging/102000000/101540000/101532600/101532511/f3c44ff0.jpg?impolicy=fcrop&w=357&h=201&p=1&q=medium) ![Lobby](https://images.trvl-media.com/lodging/102000000/101540000/101532600/101532511/5ac349d7.jpg?impolicy=fcrop&w=357&h=201&p=1&q=medium) ### Quality Inn Slidell I-10 Slidell 7.6/10 Good (223) "Good spot for one night " CA $82 CA $96 total includes taxes & fees Oct 20 - Oct 21 [](https://www.expedia.ca/New-Orleans-Hotels-Quality-Inn.h101532511.Hotel-Information) ![Front of property - evening/night](https://images.trvl-media.com/lodging/1000000/530000/526400/526304/6130fa7f.jpg?impolicy=fcrop&w=357&h=201&p=1&q=medium) ![Front of property](https://images.trvl-media.com/lodging/1000000/530000/526400/526304/fc4a15b3.jpg?impolicy=fcrop&w=357&h=201&p=1&q=medium) ![Free toiletries, hair dryer, towels, soap](https://images.trvl-media.com/lodging/1000000/530000/526400/526304/11b8b623.jpg?impolicy=fcrop&w=357&h=201&p=1&q=medium) ![Suite, 1 King Bed with Sofa bed, Non Smoking](https://images.trvl-media.com/lodging/1000000/530000/526400/526304/971ec382.jpg?impolicy=fcrop&w=357&h=201&p=1&q=medium) ### Baymont by Wyndham Slidell Slidell 8.0/10 Very good (622) "Friendly staff and clean room. It is a very old hotel but it’s clean and comfortable." CA $91 CA $105 total includes taxes & fees Oct 27 - Oct 28 [](https://www.expedia.ca/New-Orleans-Hotels-Sleep-Inn-Slidell.h526304.Hotel-Information) ![Suite, 2 Queen Beds](https://images.trvl-media.com/lodging/10000000/9770000/9767000/9766950/5afce122.jpg?impolicy=fcrop&w=357&h=201&p=1&q=medium) ![Lobby sitting area](https://images.trvl-media.com/lodging/10000000/9770000/9767000/9766950/9351deed.jpg?impolicy=fcrop&w=357&h=201&p=1&q=medium) ![Exterior](https://images.trvl-media.com/lodging/10000000/9770000/9767000/9766950/f5abc0dc.jpg?impolicy=fcrop&w=357&h=201&p=1&q=medium) ![Free daily buffet breakfast](https://images.trvl-media.com/lodging/10000000/9770000/9767000/9766950/78b260bc.jpg?impolicy=fcrop&w=357&h=201&p=1&q=medium) ### Holiday Inn Express Slidell by IHG Slidell 9.4/10 Exceptional (900) "Would recommend as an excellent place to stay." CA $128 CA $148 total includes taxes & fees Oct 19 - Oct 20 [](https://www.expedia.ca/New-Orleans-Hotels-Holiday-Inn-Express-Slidell.h9766950.Hotel-Information) ![Lobby](https://images.trvl-media.com/lodging/3000000/2470000/2469100/2469031/a3ce71af.jpg?impolicy=fcrop&w=357&h=201&p=1&q=medium) ![Standard Room, 2 Queen Beds, Non Smoking](https://images.trvl-media.com/lodging/3000000/2470000/2469100/2469031/4b3ec9ee.jpg?impolicy=fcrop&w=357&h=201&p=1&q=medium) ![Free daily continental breakfast](https://images.trvl-media.com/lodging/3000000/2470000/2469100/2469031/763dd536.jpg?impolicy=fcrop&w=357&h=201&p=1&q=medium) ![Property amenity](https://images.trvl-media.com/lodging/3000000/2470000/2469100/2469031/7f9218b9.jpg?impolicy=fcrop&w=357&h=201&p=1&q=medium) ### Quality Inn & Suites Slidell Slidell 8.6/10 Excellent (926) "Very friendly staff & good breakfast" CA $104 CA $121 total includes taxes & fees Oct 16 - Oct 17 [](https://www.expedia.ca/New-Orleans-Hotels-Quality-Inn-Suites.h2469031.Hotel-Information) ![Lobby](https://images.trvl-media.com/lodging/1000000/50000/49900/49812/2531a1ea.jpg?impolicy=fcrop&w=357&h=201&p=1&q=medium) ![Point of interest](https://images.trvl-media.com/lodging/1000000/50000/49900/49812/w794h565x3y4-ca5a4d6f.jpg?impolicy=fcrop&w=357&h=201&p=1&q=medium) ![Free daily continental breakfast](https://images.trvl-media.com/lodging/1000000/50000/49900/49812/be68d9cc.jpg?impolicy=fcrop&w=357&h=201&p=1&q=medium) ![Golf](https://images.trvl-media.com/lodging/1000000/50000/49900/49812/c23c1358.jpg?impolicy=fcrop&w=357&h=201&p=1&q=medium) ### Ramada by Wyndham Diamondhead I-10/Gulfport Diamondhead 8.0/10 Very good (529) "Very affordable and conveniently. " CA $105 CA $115 total includes taxes & fees Oct 15 - Oct 16 [](https://www.expedia.ca/Biloxi-Hotels-Ramada-By-Wyndham-Diamondhead-I-10Gulfport.h49812.Hotel-Information) ![3 restaurants, breakfast, lunch, dinner served; seafood](https://images.trvl-media.com/lodging/13000000/12690000/12685300/12685296/86740aab.jpg?impolicy=fcrop&w=357&h=201&p=1&q=medium) ![Double Room, Smoking](https://images.trvl-media.com/lodging/13000000/12690000/12685300/12685296/3923ebb5.jpg?impolicy=fcrop&w=357&h=201&p=1&q=medium) ![Desk, blackout drapes, iron/ironing board, free WiFi](https://images.trvl-media.com/lodging/13000000/12690000/12685300/12685296/5c21d6dd.jpg?impolicy=fcrop&w=357&h=201&p=1&q=medium) ![On the beach, white sand](https://images.trvl-media.com/lodging/13000000/12690000/12685300/12685296/fd395576.jpg?impolicy=fcrop&w=357&h=201&p=1&q=medium) ### Silver Slipper Casino & Hotel - Adults Only Bay St Louis 8.6/10 Excellent (1003) "Clean room & friendly staff" CA $111 CA $121 total includes taxes & fees Oct 15 - Oct 16 [](https://www.expedia.ca/Biloxi-Hotels-Silver-Slipper-Casino-Hotel.h12685296.Hotel-Information) ![Front of property](https://images.trvl-media.com/lodging/12000000/11270000/11266100/11266063/5844a2ef.jpg?impolicy=fcrop&w=357&h=201&p=1&q=medium) ![Free daily buffet breakfast](https://images.trvl-media.com/lodging/12000000/11270000/11266100/11266063/9e6b0e67.jpg?impolicy=fcrop&w=357&h=201&p=1&q=medium) ![Terrace/patio](https://images.trvl-media.com/lodging/12000000/11270000/11266100/11266063/69070001.jpg?impolicy=fcrop&w=357&h=201&p=1&q=medium) ![Lobby](https://images.trvl-media.com/lodging/12000000/11270000/11266100/11266063/86e26e21.jpg?impolicy=fcrop&w=357&h=201&p=1&q=medium) ### Comfort Inn & Suites Slidell 8.8/10 Excellent (1005) "Good stay" CA $124 CA $144 total includes taxes & fees Oct 27 - Oct 28 [](https://www.expedia.ca/New-Orleans-Hotels-Comfort-Inn-Suites.h11266063.Hotel-Information) Lowest nightly price found within the past 24 hours based on a 1 night stay for 2 adults. Prices and availability subject to change. Additional terms may apply. [View all properties](https://expedia.ca/Hotel-Search?startDate=2025-10-28&endDate=2025-10-29®ionId=9372&adults=2&travelerType=business_friendly&sort=RECOMMENDED&openPlayBack=true) ## Top Picayune Hotel Reviews ![Holiday Inn Covington by IHG](//images.trvl-media.com/lodging/9000000/8380000/8370400/8370311/954b4dc8_y.jpg) ### Holiday Inn Covington by IHG 10/10 Excellent "Staff allowed us to check out late and were very amiable. " [](https://expedia.ca/Hammond-Hotels-Holiday-Inn-Covington.h8370311.Hotel-Information) ![Country Inn & Suites by Radisson, Covington, LA](//images.trvl-media.com/lodging/3000000/2810000/2804100/2804087/54985ef1_y.jpg) ### Country Inn & Suites by Radisson, Covington, LA 10/10 Excellent "The staff at check in was super nice and helpful." [](https://expedia.ca/Hammond-Hotels-Country-Inn-Suites-By-Radisson.h2804087.Hotel-Information) ![Homewood Suites Slidell](//images.trvl-media.com/lodging/4000000/3620000/3618300/3618226/w3837h2558x3y3-21c2b95c_y.jpg) ### Homewood Suites Slidell 10/10 Excellent "Good" [](https://expedia.ca/New-Orleans-Hotels-Homewood-Suites-Slidell.h3618226.Hotel-Information) ![WeStay Suites - Covington Mandeville](//images.trvl-media.com/lodging/3000000/2950000/2949900/2949827/66d8e7f3_y.jpg) ### WeStay Suites - Covington Mandeville 10/10 Excellent "Everything was nice and clean. I had to pay 113 a night when I booked it for 97 a night " [](https://expedia.ca/Hammond-Hotels-WeStay-Suites-CovingtonMandeville.h2949827.Hotel-Information) ![Hollywood Casino Gulf Coast](//images.trvl-media.com/lodging/1000000/530000/526700/526688/d677d4b8_y.jpg) ### Hollywood Casino Gulf Coast 10/10 Excellent "The only thing that wasn’t to my liking was pillows too soft. Bed was nice. HVAC for room was great, kept temps within 1 degree up/down. I’ve stayed in hotels for business, over 1,000 nights worldwide, … this was the BEST!" [](https://expedia.ca/Biloxi-Hotels-Hollywood-Casino-Gulf-Coast.h526688.Hotel-Information) ![Ramada by Wyndham Diamondhead I-10/Gulfport](//images.trvl-media.com/lodging/1000000/50000/49900/49812/2531a1ea_y.jpg) ### Ramada by Wyndham Diamondhead I-10/Gulfport 10/10 Excellent "Room very clean, didn't experience any other service." [](https://expedia.ca/Biloxi-Hotels-Ramada-By-Wyndham-Diamondhead-I-10Gulfport.h49812.Hotel-Information) ![Courtyard by Marriott New Orleans Covington/Mandeville](//images.trvl-media.com/lodging/1000000/70000/64200/64156/d6215bcf_y.jpg) ### Courtyard by Marriott New Orleans Covington/Mandeville 10/10 Excellent "Many drink options no Coke products…hot tub was excellent. " [](https://expedia.ca/Hammond-Hotels-Courtyard-By-Marriott-New-Orleans-CovingtonMandeville.h64156.Hotel-Information) ![Holiday Inn Express Picayune-Stennis Space Center by IHG](//images.trvl-media.com/lodging/3000000/2670000/2665100/2665063/f291f597_y.jpg) ### Holiday Inn Express Picayune-Stennis Space Center by IHG 10/10 Excellent "Everything was great" [](https://expedia.ca/Picayune-Hotels-Holiday-Inn-Express-Picayune-Stennis-Space-Center.h2665063.Hotel-Information) ![Heritage Inn Picayune](//images.trvl-media.com/lodging/3000000/2460000/2455400/2455338/c2f5774a_y.jpg) ### Heritage Inn Picayune 10/10 Excellent "Good staff and convenient." [](https://expedia.ca/Picayune-Hotels-Heritage-Inn-Picayune.h2455338.Hotel-Information) ## Frequently asked questions ### How much do business-friendly hotels in Picayune cost? > Rates for business hotels in Picayune range between CA $96 and CA $148 per night. No matter your budget, Expedia can help you find the right place for a smooth work trip. These prices were available on Expedia within the past 7 days, for a hotel booking with a check-in date within the next year. Prices reflect current offers and availability is subject to change. Additional terms may apply. ### What are the best business-friendly hotels in Picayune? > Picayune has multiple business-friendly hotels with a total average guest review rating of 7.9. One of the most popular is [Holiday Inn Express Picayune-Stennis Space Centre, an IHG Hotel](https://www.expedia.ca/Picayune-Hotels-Holiday-Inn-Express-Picayune-Stennis-Space-Center.h2665063.Hotel-Information). Get the job done from this 2.5-stars option, which includes pool sun loungers and a swimming pool. Another favourite with corporate travellers is [Heritage Inn Picayune](https://www.expedia.ca/Picayune-Hotels-Heritage-Inn-Picayune.h2455338.Hotel-Information). It has a 2-stars rating and amenities such as complimentary breakfast and front desk services. ### How many business-friendly hotels are there in Picayune? > Picayune offers 4 hotels that accommodate corporate travellers. Whether you're searching for a central location or conveniences such as conference rooms and dependable WiFi, you'll find the perfect property on Expedia. ### What are the top business-friendly motels in Picayune? > [Super 8 by Wyndham Picayune](https://www.expedia.ca/Picayune-Hotels-Super-8-By-Wyndham-Picayune.h1926144.Hotel-Information) perfectly combines work and play. A garden and a barbecue grill are among the many amenities at this business-friendly option, located around 3 kilometres northeast of the centre of Picayune.You'll find plenty of things to see and experience around Picayune. Take time out from your work schedule to visit leading attractions like [Millbrook Country Club](https://www.expedia.ca/Millbrook-Country-Club-Picayune.d6317721.Vacation-Attraction) and [Crosby Arboretum](https://www.expedia.ca/Crosby-Aboretum-Picayune.d6317725.Vacation-Attraction). ### Are there any family-friendly hotels in Picayune that are also business friendly? > Family travellers and corporate guests are well cared for at [Holiday Inn Express Picayune-Stennis Space Centre, an IHG Hotel](https://www.expedia.ca/Picayune-Hotels-Holiday-Inn-Express-Picayune-Stennis-Space-Center.h2665063.Hotel-Information). This popular 2.5-stars property in Picayune comes with a good range of amenities, such as complimentary breakfast and housekeeping services. Picayune has loads of family-friendly attractions to discover when you're done with work. Take the kids on an outing to [Crosby Arboretum](https://www.expedia.ca/Crosby-Aboretum-Picayune.d6317725.Vacation-Attraction) and [Millbrook Country Club](https://www.expedia.ca/Millbrook-Country-Club-Picayune.d6317721.Vacation-Attraction). ### Why book your business-friendly hotel in Picayune with Expedia? > With amenities like conference rooms, room service and on-site cafés, our business-friendly properties come with all you'll need to get the job done — and then unwind! Enter your preferred travel dates and destination and Expedia will help you organize the rest. ### How can I find cheap business-friendly hotels in Picayune? > When work takes you on the road in Picayune, our "business friendly" filter will help you find the right hotel. From free WiFi and included breakfast to meeting rooms and workspaces, they come with the amenities you need to be productive. Another tip? Narrow your search by your budget and preferred star rating to see the most affordable accommodations. ### What is there to do in Picayune near my business-friendly hotel? > If you want to make the most of your downtime in Picayune, don't miss [Millbrook Country Club](https://www.expedia.ca/Millbrook-Country-Club-Picayune.d6317721.Vacation-Attraction). 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