Pemiscot County Vacation Packages

Book a Hotel + Flight or Car together to unlock savings

  • Plan, book, travel with confidence

  • Better together

    Save up to CA $4,200 when you book a flight and hotel together*

  • Find the right fit

    With over 300,000 hotels worldwide, it's easy to create a perfect package

  • Rest easy

    Plan, book, and manage your trip all in one place

Top Pemiscot County Vacation Deals

Price found within the past 48 hours. Click for updated prices.
The Louis Hotel

The Louis Hotel

4 out of 5
Price was CA $901, price is now CA $749 per person
CA $749
per person
Jun 30 - Jul 2
found 6 hours ago
Roundtrip flight included
Miami (MIA) to Jonesboro (JBR)
9.6/10 Exceptional! (65 reviews)
Beautiful rooms. Very comfortable and cozy. The staff is very nice and helpful. Gym is good although I couldn’t get internet there.

Reviewed on May 17, 2026

Pemiscot County Hotel Deals

Drury Inn & Suites Hayti Caruthersville

Drury Inn & Suites Hayti Caruthersville

3 out of 5
1317 E Highway 84 Hayti MO
Fully refundableReserve now, pay when you stay
The price is CA $144 per night from Jun 7 to Jun 8
CA $144
CA $164 total
Jun 7 - Jun 8
includes taxes & fees
9.4/10 Exceptional! (1,002 reviews)
"Awesome experience and comfortable stay . Cleanest stay ever"

Reviewed on May 24, 2026

Drury Inn & Suites Hayti Caruthersville
The Farmstead Hotel

The Farmstead Hotel

2.5 out of 5
778 E 3rd St Caruthersville MO
Fully refundableReserve now, pay when you stay
The price is CA $131 per night from May 26 to May 27
CA $131
CA $149 total
May 26 - May 27
includes taxes & fees
8.6/10 Excellent! (553 reviews)
"This property had no amenities as far as breakfast. Our room was very loud Friday. We had attempted to call the front desk, a couple of different times and did not get an answer."

Reviewed on May 23, 2026

The Farmstead Hotel
Century Casino & Hotel Caruthersville

Century Casino & Hotel Caruthersville

3 out of 5
777 E 3rd St Caruthersville MO
Fully refundableReserve now, pay when you stay
The price is CA $154 per night from May 26 to May 27
CA $154
CA $176 total
May 26 - May 27
includes taxes & fees
8.6/10 Excellent! (156 reviews)
"The town where located has no real breakfast spots and the hotel doesn't offer breakfast during the week and there are no microwaves in rooms. Otherwise stay was what I expected, nothing more, nothing less. Tipped staff who helped me look for lost key fob.Thank you!!!!!"

Reviewed on May 20, 2026

Century Casino & Hotel Caruthersville
See all 111 properties in Pemiscot County
Lowest nightly price found within the past 24 hours based on a 1 night stay for 2 adults. Prices and availability subject to change. Additional terms may apply.
All Inclusive Vacations
All Inclusive Vacations
Beach Vacations
Beach Vacations
Family Vacations
Family Vacations

Frequently asked questions

How much does a Pemiscot County vacation package cost?
Choose from any combination of car rentals, flights and hotels, and you can be vacationing in Pemiscot County from just CA $749. And the more you bundle, the more you save. The vacation of your dreams has never been so affordable.
How do I get a cheap travel package to Pemiscot County?
It's easy. Just bundle. Flights, rental cars and hotels — combine whatever you need into a Pemiscot County vacation package to save a pile of cash. Score even more discounts when you add extras such as activities or tours to your booking. But that's not the only impressive part. You have the flexibility to put together your trip your way. We offer more than 550 airlines and 1,000,000 hotels across the world, so that everyone has a chance to travel and live out those vacation fantasies.
How far in advance should I book my Pemiscot County vacation?
Browse Expedia to compare international airfares as soon as possible. In most cases, you can purchase a ticket up to 12 months prior to departure. If you can't see your preferred air carrier, or you've left things to the last moment, don't despair. The lowest prices to Pemiscot County sometimes appear within weeks of the date of departure.
What does an Expedia Pemiscot County travel package include?
Expedia has everything you need to plan your Pemiscot County getaway, but what your package looks like is your call. Choose from a combination of hotels, rental cars and flights. Looking for some experiences or tours to keep you entertained? Once you've made your booking, you can add them too. Whatever your budget or style, there's a package to meet your needs.
What should I know before booking a Pemiscot County travel package?
An Expedia travel package can be customized for your circumstances and is an easy way to stretch your dollars further. What you include is completely up to you. Hotels, rental cars and flights — come up with a combination that works with your plans.
Can I choose my airline with a Pemiscot County Expedia vacation package?
Most definitely. We have access to over 550 airlines worldwide, so you can tailor your Pemiscot County trip according to your budget and needs.
If I'm not able to travel, can I cancel my Pemiscot County vacation package?
It's difficult to predict what the future holds, so it's comforting to know that you can change or cancel your Pemiscot County vacation package. If you made your booking in the last 24 hours, you may be eligible for a refund. If it's an older booking, your hotel, airline or car rental company may charge a fee. Visit our Customer Service Portal to learn more.
* Savings based on package bookings compared to the price of the same components booked separately. Savings not available on all packages.