Title: Hotels by La Quinta Inn & Suites in Panhandle from CA $166 | Expedia.ca [Panhandle Travel Guide](https://expedia.ca/San-Francisco-Panhandle.dx553248635976468721)[Vacation Rentals in San Francisco](https://expedia.ca/San-Francisco-Vacation-Rentals.d178305.Travel-Guide-VacationRentals)[Flights to San Francisco](https://expedia.ca/Cheap-Flights-To-San-Francisco.d178305.Travel-Guide-Flights)[Things to do in San Francisco](https://expedia.ca/Things-To-Do-In-San-Francisco.d178305.Travel-Guide-Activities)[Panhandle Car Rentals](https://expedia.ca/Car-Rentals-In-Panhandle.d553248635976468721.Car-Rental-Guide)[Panhandle Vacations](https://expedia.ca/Panhandle.d553248635976468721.Destination-Travel-Guides) ![](https://mediaim.expedia.com/destination/2/5503bad6c63e28cf4aee74831be6c77e.jpg?impolicy=fcrop&w=1200&h=500&q=medium) Photo by Debbie Morey # Find Hotels by La Quinta Inn & Suites in Panhandle from CA $166 ![](https://a.travel-assets.com/travel-assets-manager/pictogram-bex/light__calendar_shield.svg) ### Change your mind Book hotels with free cancellation ![](https://a.travel-assets.com/travel-assets-manager/pictogram-bex/light__deals.svg) ### Treat yourself Sign in to save 10% or more on thousands of hotels [Sign in](https://www.expedia.ca/login) ![](https://a.travel-assets.com/travel-assets-manager/pictogram-bex/light__bed.svg) ### Be picky Search almost a million properties worldwide ## Check prices for these dates Tonight [Oct 12 - Oct 13](https://www.expedia.ca/Hotel-Search?regionId=553248635976468721&startDate=2025-10-12&endDate=2025-10-13&adults=2&rfrr=TG.LP.CheckPrices.Hotel&openPlayBack=true) Tomorrow [Oct 13 - Oct 14](https://www.expedia.ca/Hotel-Search?regionId=553248635976468721&startDate=2025-10-13&endDate=2025-10-14&adults=2&rfrr=TG.LP.CheckPrices.Hotel&openPlayBack=true) Next weekend [Oct 17 - Oct 19](https://www.expedia.ca/Hotel-Search?regionId=553248635976468721&startDate=2025-10-17&endDate=2025-10-19&adults=2&rfrr=TG.LP.CheckPrices.Hotel&openPlayBack=true) In two weeks [Oct 24 - Oct 26](https://www.expedia.ca/Hotel-Search?regionId=553248635976468721&startDate=2025-10-24&endDate=2025-10-26&adults=2&rfrr=TG.LP.CheckPrices.Hotel&openPlayBack=true) ## Top Panhandle La Quinta Inn & Suites Hotels ![Garden](https://images.trvl-media.com/lodging/1000000/30000/27000/26945/a57ff5b7.jpg?impolicy=fcrop&w=357&h=201&p=1&q=medium) ![Fridge, microwave, dishwasher, coffee/tea maker](https://images.trvl-media.com/lodging/1000000/30000/27000/26945/91034226.jpg?impolicy=fcrop&w=357&h=201&p=1&q=medium) ![Lobby sitting area](https://images.trvl-media.com/lodging/1000000/30000/27000/26945/2e422e8e.jpg?impolicy=fcrop&w=357&h=201&p=1&q=medium) ![Garden](https://images.trvl-media.com/lodging/1000000/30000/27000/26945/9d0e9bfe.jpg?impolicy=fcrop&w=357&h=201&p=1&q=medium) ### La Quinta Inn & Suites by Wyndham San Francisco Airport West Millbrae 8.6/10 Excellent (1424) "Breakfast is good; room is clean, and the staff are amazing." CA $182 CA $209 total includes taxes & fees Oct 24 - Oct 25 [](https://www.expedia.ca/San-Francisco-Hotels-La-Quinta-Inn-Suites-By-Wyndham-San-Francisco-Airport-West.h26945.Hotel-Information) ![Exterior](https://images.trvl-media.com/lodging/1000000/10000/9400/9329/5d196618.jpg?impolicy=fcrop&w=357&h=201&p=1&q=medium) ![Deluxe Suite, Multiple Beds, Accessible, Non Smoking (Mobility/Hearing Impaired Accessible)](https://images.trvl-media.com/lodging/1000000/10000/9400/9329/6c7a44bf.jpg?impolicy=fcrop&w=357&h=201&p=1&q=medium) ![Fitness facility](https://images.trvl-media.com/lodging/1000000/10000/9400/9329/3bdf7c8a.jpg?impolicy=fcrop&w=357&h=201&p=1&q=medium) ![Free daily continental breakfast](https://images.trvl-media.com/lodging/1000000/10000/9400/9329/4becccdf.jpg?impolicy=fcrop&w=357&h=201&p=1&q=medium) ### La Quinta Inn & Suites by Wyndham San Francisco Airport N Downtown South San Francisco 8.0/10 Very good (2017) "Great place to stay " CA $142 CA $166 total includes taxes & fees Oct 26 - Oct 27 [](https://www.expedia.ca/San-Francisco-Hotels-La-Quinta-Inn-Suites-By-Wyndham-San-Francisco-Airport-N.h9329.Hotel-Information) Lowest nightly price found within the past 24 hours based on a 1 night stay for 2 adults. Prices and availability subject to change. Additional terms may apply. [View all properties](https://expedia.ca/Hotel-Search?startDate=2025-10-26&endDate=2025-10-27®ionId=553248635976468721&adults=2&sort=RECOMMENDED&openPlayBack=true) ![](https://a.travel-assets.com/pricing-claim/sparkle_dark.svg) Save an average of 15% on thousands of hotels when you're signed in [Sign in](https://expedia.ca/user/signin?ckoflag=0&uurl=e3id%3Dredr%26rurl%3D%2FPanhandle-San-Francisco-Hotels-La-Quinta-Inn-Suites.0-n553248635976468721-0--bLaQuintaInnSuites.Travel-Guide-Filter-Hotels)[Sign up, it's free](https://expedia.ca/signup?enable_registration=true&+=&uurl=e3id%3Dredr%26rurl%3D%2FPanhandle-San-Francisco-Hotels-La-Quinta-Inn-Suites.0-n553248635976468721-0--bLaQuintaInnSuites.Travel-Guide-Filter-Hotels) ## Top Panhandle Hotel Reviews ![Hilton San Francisco Financial District](//images.trvl-media.com/lodging/1000000/10000/4400/4302/77af977e_y.jpg) ### Hilton San Francisco Financial District 10/10 Excellent "Great location! Bar needs to be restocked " [](https://expedia.ca/San-Francisco-Hotels-Hilton-San-Francisco-Financial-District.h4302.Hotel-Information) ![Handlery Union Square Hotel](//images.trvl-media.com/lodging/1000000/10000/6700/6666/b8dfc462_y.jpg) ### Handlery Union Square Hotel 10/10 Excellent "The staff was very helpful and the room was kept very clean. Just a note the pool is not suitable for lap swimming but great for lounging. I would recommend that the hotel put in a small motion sensitive light in the bathroom. Those 2 things aside I enjoyed my stay." [](https://expedia.ca/San-Francisco-Hotels-Handlery-Union-Square-Hotel.h6666.Hotel-Information) ![The Pickwick Hotel](//images.trvl-media.com/lodging/1000000/20000/11800/11793/060ec935_y.jpg) ### The Pickwick Hotel 10/10 Excellent "Everything is good." [](https://expedia.ca/San-Francisco-Hotels-The-Pickwick-Hotel.h11793.Hotel-Information) ![Hyatt Regency San Francisco](//images.trvl-media.com/lodging/1000000/30000/23800/23774/1f7903cc_y.jpg) ### Hyatt Regency San Francisco 10/10 Excellent "The staff around the property is very nice and helpful. I love staying here because it's a safe place and close to a lot of amenities. " [](https://expedia.ca/San-Francisco-Hotels-Hyatt-Regency-San-Francisco.h23774.Hotel-Information) ![Bay Landing San Francisco Airport Hotel](//images.trvl-media.com/lodging/2000000/1120000/1110800/1110785/0c231d9b_y.jpg) ### Bay Landing San Francisco Airport Hotel 10/10 Excellent "The staff is friendly and kind. Our room was brand well appointed. Huge room too!! Breakfast was delicious with amazing omelets! " [](https://expedia.ca/San-Francisco-Hotels-Bay-Landing-San-Francisco-Airport-Hotel.h1110785.Hotel-Information) ![FOUND Hotel Carlton, Nob Hill](//images.trvl-media.com/lodging/104000000/103130000/103126600/103126565/818bb89d_y.jpg) ### FOUND Hotel Carlton, Nob Hill 10/10 Excellent "Great staff!" [](https://expedia.ca/San-Francisco-Hotels-FOUND-Hotel-San-Francisco-Carlton.h103126565.Hotel-Information) ![Hotel Caza Fisherman's Wharf](//images.trvl-media.com/lodging/39000000/38250000/38249400/38249309/0bf5bd4c_y.jpg) ### Hotel Caza Fisherman's Wharf 10/10 Excellent "Rooms are a nice size! The cleaning staff were incredible. It seemed every day they did a little bit extra. Was very pleased. Very close to fisherman’s wharf which is where a lot of your tourist spots are so being able to walk easily around was super convenient. A little noisy though at night (outside not inside) but comes with the touristy area I think. Security was always present. Doors locked at night. Happy with our stay!" [](https://expedia.ca/San-Francisco-Hotels-Hotel-Caza.h38249309.Hotel-Information) ![Holiday Inn Golden Gateway by IHG](//images.trvl-media.com/lodging/1000000/20000/10600/10538/9ba9bb1f_y.jpg) ### Holiday Inn Golden Gateway by IHG 10/10 Excellent "The view from our corner room was awesome. Close and easy transportation options to get around . Excellent choices for restaurants all walking distance " [](https://expedia.ca/San-Francisco-Hotels-Holiday-Inn-Golden-Gateway.h10538.Hotel-Information) ![Comfort Inn by the Bay](//images.trvl-media.com/lodging/1000000/10000/6000/5984/d439a184_y.jpg) ### Comfort Inn by the Bay 10/10 Excellent "Pizza nearby outstanding " [](https://expedia.ca/San-Francisco-Hotels-Comfort-Inn-By-The-Bay.h5984.Hotel-Information) ## Find out more about Panhandle ## Panhandle Hotels Guide Expedia.ca offers a selection of 4550 hotels in Panhandle. You are sure to find cheap deals and discount rates among them with our Best Price Guarantee. No matter what type of hotel strikes your fancy, we will let you search for your preferred one to accommodate your travel needs. Expedia.ca will not only save you time, but also money when booking your stay at a hotel in Panhandle. Making reservations so you can stay within your budget is easy with us. Expedia.ca even provides you with a map so you may find hotels in the Panhandle neighborhood you prefer. Go ahead. Enter your travel dates to view the best offers on hotel rooms in Panhandle, San Francisco now! ## Explore a world of travel with Expedia - Lodging - Flights - Packages - Cars - Other - More ways to book - [Hotels near Alamo Square](https://www.expedia.ca/Alamo-Square-Hotels.0-l507476-0.Travel-Guide-Filter-Hotels) - [Anza Vista Hotels](https://www.expedia.ca/Anza-Vista-San-Francisco-Hotels.0-n553248635976478191-0.Travel-Guide-Filter-Hotels) - [Ashbury Heights Hotels](https://www.expedia.ca/Ashbury-Heights-San-Francisco-Hotels.0-n553248635976471431-0.Travel-Guide-Filter-Hotels) - [Hotels near Buena Vista Park](https://www.expedia.ca/Buena-Vista-Park-Hotels.0-l507466-0.Travel-Guide-Filter-Hotels) - [Buena Vista Hotels](https://www.expedia.ca/Buena-Vista-San-Francisco-Hotels.0-n553248635976482255-0.Travel-Guide-Filter-Hotels) - [Residences in Carl St & Hillway Ave Stop](https://www.expedia.ca/Carl-St-Hillway-Ave-Stop-Residences.d553248635995267518-aaResidences.Travel-Guide-Accommodation) - 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[Union Square Hotels](https://www.expedia.ca/Union-Square-San-Francisco-Hotels.0-n800129-0.Travel-Guide-Filter-Hotels) - [Hotels near University of California](https://www.expedia.ca/University-Of-California-Hotels.0-l6151904-0.Travel-Guide-Filter-Hotels) - [Hotels near University of San Francisco](https://www.expedia.ca/University-Of-San-Francisco-Hotels.0-l502586-0.Travel-Guide-Filter-Hotels) - [Hotels near Vulcan Steps](https://www.expedia.ca/Vulcan-Steps-Hotels.0-l553248621555612100-0.Travel-Guide-Filter-Hotels) - [Flights to San Francisco](https://www.expedia.ca/Cheap-Flights-To-San-Francisco.d178305.Travel-Guide-Flights) - [Flights from Vancouver (YVR) to San Francisco (SFO)](https://www.expedia.ca/lp/flights/yvr/sfo/vancouver-to-san-francisco) - [Flights from Toronto (YYZ) to San Francisco (SFO)](https://www.expedia.ca/lp/flights/yyz/sfo/toronto-to-san-francisco) - [Conservatory of Flowers](https://www.expedia.ca/Conservatory-Of-Flowers-Golden-Gate.d6069419.Vacation-Attraction) - [Haight Street](https://www.expedia.ca/Haight-Street-Haight-Ashbury.d553248621533113893.Vacation-Attraction) - [Kaiser Permanente Medical Center](https://www.expedia.ca/Kaiser-Permanente-Medical-Center-Western-Addition.d6177656.Vacation-Attraction) - [Neptune Society Columbarium](https://www.expedia.ca/Neptune-Society-Columbarium-Richmond-District.d6155323.Vacation-Attraction) - [Visit Anza Vista](https://www.expedia.ca/San-Francisco-Anza-Vista.dx553248635976478191) - [Visit Ashbury Heights](https://www.expedia.ca/San-Francisco-Ashbury-Heights.dx553248635976471431) - [Visit Cole Valley](https://www.expedia.ca/San-Francisco-Cole-Valley.dx3000663429) - [Visit Haight-Ashbury](https://www.expedia.ca/San-Francisco-Haight-Ashbury.dx111752) - [Visit Laurel Heights](https://www.expedia.ca/San-Francisco-Laurel-Heights.dx6151732) - [San Francisco Vacations](https://www.expedia.ca/San-Francisco.d178305.Destination-Travel-Guides) - [Car rentals near San Francisco](https://www.expedia.ca/Car-Rentals-In-San-Francisco.d178305.Car-Rental-Guide) - [Things to do in San Francisco](https://www.expedia.ca/Things-To-Do-In-San-Francisco.d178305.Travel-Guide-Activities) - [Book Hotels in Panhandle on Expedia.com](https://www.expedia.com/Panhandle-San-Francisco-Hotels-La-Quinta-Inn-Suites.0-n553248635976468721-0--bLaQuintaInnSuites.Travel-Guide-Filter-Hotels)