Title: Book the Best BUSINESS Hotels in Panhandle Plains in 2026 | Expedia.ca [Panhandle Plains Travel Guide](https://expedia.ca/Panhandle-Plains.dx6058805)[Hotels in Panhandle Plains](https://expedia.ca/Panhandle-Plains-Hotels.d6058805.Travel-Guide-Hotels)[Vacation Rentals in Panhandle Plains](https://expedia.ca/Panhandle-Plains-Vacation-Rentals.d6058805.Travel-Guide-VacationRentals)[Flights to Panhandle Plains](https://expedia.ca/Cheap-Flights-To-Panhandle-Plains.d6058805.Travel-Guide-Flights)[Panhandle Plains Car Rentals](https://expedia.ca/Car-Rentals-In-Panhandle-Plains.d6058805.Car-Rental-Guide)[Panhandle Plains Vacation Packages](https://expedia.ca/Panhandle-Plains.d6058805.Destination-Travel-Guides) ![Lubbock which includes a windmill and tranquil scenes](https://images.trvl-media.com/place/6131013/17de49c6-a1c8-47d1-b6c1-9dad01a3e5c3.jpg?impolicy=fcrop&w=1200&h=500&q=medium) Photo by Courtesy of Visit Lubbock # Find Business Hotels in Panhandle Plains, TX - ![](https://a.travel-assets.com/travel-assets-manager/pictogram-bex/light__calendar_shield.svg) ### Change your mind Book hotels with free cancellation - ![](https://a.travel-assets.com/travel-assets-manager/pictogram-bex/light__deals.svg) ### Treat yourself Sign in to save 10% or more on thousands of hotels [Sign in](https://www.expedia.ca/login) - ![](https://a.travel-assets.com/travel-assets-manager/pictogram-bex/light__bed.svg) ### Be picky Search almost a million properties worldwide ## Check availability on Panhandle Plains Business Hotels Tonight [Dec 17 - Dec 18](https://www.expedia.ca/Hotel-Search?regionId=6058805&startDate=2025-12-17&endDate=2025-12-18&adults=2&rfrr=TG.LP.CheckPrices.Hotel&openPlayBack=true&travelerType=business_friendly) Tomorrow [Dec 18 - Dec 19](https://www.expedia.ca/Hotel-Search?regionId=6058805&startDate=2025-12-18&endDate=2025-12-19&adults=2&rfrr=TG.LP.CheckPrices.Hotel&openPlayBack=true&travelerType=business_friendly) This weekend [Dec 19 - Dec 21](https://www.expedia.ca/Hotel-Search?regionId=6058805&startDate=2025-12-19&endDate=2025-12-21&adults=2&rfrr=TG.LP.CheckPrices.Hotel&openPlayBack=true&travelerType=business_friendly) Next weekend [Dec 26 - Dec 28](https://www.expedia.ca/Hotel-Search?regionId=6058805&startDate=2025-12-26&endDate=2025-12-28&adults=2&rfrr=TG.LP.CheckPrices.Hotel&openPlayBack=true&travelerType=business_friendly) ## Our top choices for Panhandle Plains business-friendly hotels ![Exterior](https://images.trvl-media.com/lodging/2000000/1530000/1529800/1529725/887f87c2.jpg?impolicy=fcrop&w=357&h=201&p=1&q=medium) ![Indoor pool](https://images.trvl-media.com/lodging/2000000/1530000/1529800/1529725/00f567a3.jpg?impolicy=fcrop&w=357&h=201&p=1&q=medium) ![Desk, laptop workspace, blackout drapes, iron/ironing board](https://images.trvl-media.com/lodging/2000000/1530000/1529800/1529725/98b35323.jpg?impolicy=fcrop&w=357&h=201&p=1&q=medium) ![Lobby](https://images.trvl-media.com/lodging/2000000/1530000/1529800/1529725/5e093502.jpg?impolicy=fcrop&w=357&h=201&p=1&q=medium) ### Drury Inn & Suites Amarillo [](https://www.expedia.ca/Amarillo-Hotels-Drury-Inn-Suites-Amarillo.h1529725.Hotel-Information) Amarillo 9.4/10 Exceptional (2195) "We had a great stay!! Friendly staff, clean rooms and enjoyed the amenities." ![United States](https://a.travel-assets.com/egds/marks/flags/us.svg) Araceli CA $117 CA $135 total includes taxes & fees Jan 11 - Jan 12, 2026 [](https://www.expedia.ca/Amarillo-Hotels-Drury-Inn-Suites-Amarillo.h1529725.Hotel-Information) ![Exterior](https://images.trvl-media.com/lodging/5000000/4280000/4270900/4270804/02449019.jpg?impolicy=fcrop&w=357&h=201&p=1&q=medium) ![Property amenity](https://images.trvl-media.com/lodging/5000000/4280000/4270900/4270804/1946cd63.jpg?impolicy=fcrop&w=357&h=201&p=1&q=medium) ![Free breakfast](https://images.trvl-media.com/lodging/5000000/4280000/4270900/4270804/9432f25c.jpg?impolicy=fcrop&w=357&h=201&p=1&q=medium) ![Exterior](https://images.trvl-media.com/lodging/5000000/4280000/4270900/4270804/5b0048f5.jpg?impolicy=fcrop&w=357&h=201&p=1&q=medium) ### Holiday Inn Express & Suites Amarillo West by IHG [](https://www.expedia.ca/Amarillo-Hotels-Holiday-Inn-Express-Hotel-Suites-Amarillo-West.h4270804.Hotel-Information) Amarillo 9.4/10 Exceptional (2000) "Great hotel " ![United States](https://a.travel-assets.com/egds/marks/flags/us.svg) Sara CA $138 CA $158 total includes taxes & fees Jan 17 - Jan 18, 2026 [](https://www.expedia.ca/Amarillo-Hotels-Holiday-Inn-Express-Hotel-Suites-Amarillo-West.h4270804.Hotel-Information) ![Lobby](https://images.trvl-media.com/lodging/2000000/1070000/1068900/1068876/7a9aad1d.jpg?impolicy=fcrop&w=357&h=201&p=1&q=medium) ![Premium bedding, desk, laptop workspace, blackout drapes](https://images.trvl-media.com/lodging/2000000/1070000/1068900/1068876/8914bdbb.jpg?impolicy=fcrop&w=357&h=201&p=1&q=medium) ![Indoor pool](https://images.trvl-media.com/lodging/2000000/1070000/1068900/1068876/e0486787.jpg?impolicy=fcrop&w=357&h=201&p=1&q=medium) ![Exterior](https://images.trvl-media.com/lodging/2000000/1070000/1068900/1068876/1787e028.jpg?impolicy=fcrop&w=357&h=201&p=1&q=medium) ### Best Western Plus Red River Inn [](https://www.expedia.ca/Childress-Hotels-Best-Western-Plus-Red-River-Inn.h1068876.Hotel-Information) Clarendon 9.4/10 Exceptional (954) "The beds were very comfortable, room was clean, breakfast was great. We had a pleasant stay." ![United States](https://a.travel-assets.com/egds/marks/flags/us.svg) Judith CA $177 CA $201 total includes taxes & fees Dec 18 - Dec 19 [](https://www.expedia.ca/Childress-Hotels-Best-Western-Plus-Red-River-Inn.h1068876.Hotel-Information) ![Terrace/patio](https://images.trvl-media.com/lodging/45000000/44380000/44370600/44370546/1081cf4a.jpg?impolicy=fcrop&w=357&h=201&p=1&q=medium) ![Lobby](https://images.trvl-media.com/lodging/45000000/44380000/44370600/44370546/6479b6b2.jpg?impolicy=fcrop&w=357&h=201&p=1&q=medium) ![Premium bedding, in-room safe, desk, free WiFi](https://images.trvl-media.com/lodging/45000000/44380000/44370600/44370546/d3e0e1e1.jpg?impolicy=fcrop&w=357&h=201&p=1&q=medium) ![Front of property - evening/night](https://images.trvl-media.com/lodging/45000000/44380000/44370600/44370546/9ed9fb8f.jpg?impolicy=fcrop&w=357&h=201&p=1&q=medium) ### Hyatt Place Amarillo-West [](https://www.expedia.ca/Amarillo-Hotels-Hyatt-Place-Amarillo-West.h44370546.Hotel-Information) Amarillo 9.2/10 Wonderful (1372) "We like to stay there when we head to Prescott, Arizona. It is convenient and has many restaurants around to chose from! The staff is super nice. " ![United States](https://a.travel-assets.com/egds/marks/flags/us.svg) Charles CA $116 CA $135 total includes taxes & fees Jan 1 - Jan 2, 2026 [](https://www.expedia.ca/Amarillo-Hotels-Hyatt-Place-Amarillo-West.h44370546.Hotel-Information) ![Exterior](https://images.trvl-media.com/lodging/13000000/12660000/12650300/12650217/3aafc5d4.jpg?impolicy=fcrop&w=357&h=201&p=1&q=medium) ![Standard Room, 2 Queen Beds, Non Smoking](https://images.trvl-media.com/lodging/13000000/12660000/12650300/12650217/dc52b529.jpg?impolicy=fcrop&w=357&h=201&p=1&q=medium) ![Lobby](https://images.trvl-media.com/lodging/13000000/12660000/12650300/12650217/00e330b5.jpg?impolicy=fcrop&w=357&h=201&p=1&q=medium) ![1 bedroom, premium bedding, desk, blackout drapes](https://images.trvl-media.com/lodging/13000000/12660000/12650300/12650217/2f7d44b5.jpg?impolicy=fcrop&w=357&h=201&p=1&q=medium) ### Comfort Inn & Suites Snyder [](https://www.expedia.ca/Sweetwater-Hotels-Comfort-Inn-Suites.h12650217.Hotel-Information) Snyder 9.2/10 Wonderful (557) "Impressively nice, clean, comfortable and stands out among the local competition." ![United States](https://a.travel-assets.com/egds/marks/flags/us.svg) Gary CA $104 CA $120 total includes taxes & fees Dec 25 - Dec 26 [](https://www.expedia.ca/Sweetwater-Hotels-Comfort-Inn-Suites.h12650217.Hotel-Information) ![Bar (on property)](https://images.trvl-media.com/lodging/17000000/16280000/16272200/16272130/3fb5eaf2.jpg?impolicy=fcrop&w=357&h=201&p=1&q=medium) ![Terrace/patio](https://images.trvl-media.com/lodging/17000000/16280000/16272200/16272130/89f26079.jpg?impolicy=fcrop&w=357&h=201&p=1&q=medium) ![Lobby](https://images.trvl-media.com/lodging/17000000/16280000/16272200/16272130/f3837c6c.jpg?impolicy=fcrop&w=357&h=201&p=1&q=medium) ![In-room safe, desk, blackout drapes, iron/ironing board](https://images.trvl-media.com/lodging/17000000/16280000/16272200/16272130/fcd3f164.jpg?impolicy=fcrop&w=357&h=201&p=1&q=medium) ### Embassy Suites by Hilton Amarillo Downtown [](https://www.expedia.ca/Amarillo-Hotels-Embassy-Suites-Amarillo-Downtown.h16272130.Hotel-Information) Downtown Amarillo 9.0/10 Wonderful (1005) "Our rooms were great, the hosts were fantastic, and the breakfast was really nice!" ![United States](https://a.travel-assets.com/egds/marks/flags/us.svg) Jonathan CA $132 CA $153 total includes taxes & fees Jan 11 - Jan 12, 2026 [](https://www.expedia.ca/Amarillo-Hotels-Embassy-Suites-Amarillo-Downtown.h16272130.Hotel-Information) ![Terrace/patio](https://images.trvl-media.com/lodging/5000000/4530000/4525900/4525899/w5754h3835x5y5-dac409e7.jpg?impolicy=fcrop&w=357&h=201&p=1&q=medium) ![Reception](https://images.trvl-media.com/lodging/5000000/4530000/4525900/4525899/w5755h3840x5y0-36324191.jpg?impolicy=fcrop&w=357&h=201&p=1&q=medium) ![Flat-screen TV](https://images.trvl-media.com/lodging/5000000/4530000/4525900/4525899/w5757h3840x4y0-fab48041.jpg?impolicy=fcrop&w=357&h=201&p=1&q=medium) ![Exterior](https://images.trvl-media.com/lodging/5000000/4530000/4525900/4525899/w5755h3835x5y5-7f4107da.jpg?impolicy=fcrop&w=357&h=201&p=1&q=medium) ### Hampton Inn Vernon [](https://www.expedia.ca/Childress-Hotels-Hampton-Inn-Vernon.h4525899.Hotel-Information) Vernon 9.4/10 Exceptional (738) "Always a quality stay at the Vernon Hampton Inn. Clean room,friendly staff." ![United States](https://a.travel-assets.com/egds/marks/flags/us.svg) Tom CA $168 CA $193 total includes taxes & fees Jan 1 - Jan 2, 2026 [](https://www.expedia.ca/Childress-Hotels-Hampton-Inn-Vernon.h4525899.Hotel-Information) ![Room, 1 King Bed, Non Smoking](https://images.trvl-media.com/lodging/1000000/30000/27500/27413/a64a0e18.jpg?impolicy=fcrop&w=357&h=201&p=1&q=medium) ![Free daily on-the-go breakfast](https://images.trvl-media.com/lodging/1000000/30000/27500/27413/cd04a6c4.jpg?impolicy=fcrop&w=357&h=201&p=1&q=medium) ![Indoor pool](https://images.trvl-media.com/lodging/1000000/30000/27500/27413/b44f2058.jpg?impolicy=fcrop&w=357&h=201&p=1&q=medium) ![Exterior](https://images.trvl-media.com/lodging/1000000/30000/27500/27413/253acd8c.jpg?impolicy=fcrop&w=357&h=201&p=1&q=medium) ### Days Inn by Wyndham Dalhart [](https://www.expedia.ca/Dalhart-Hotels-Days-Inn-By-Wyndham-Dalhart.h27413.Hotel-Information) Dalhart 8.0/10 Very good (764) "The pool was great and nice and warm. The hot tub was wonderful Room clean and the staff friendly and help full." ![United States](https://a.travel-assets.com/egds/marks/flags/us.svg) Mike CA $164 CA $185 total includes taxes & fees Dec 18 - Dec 19 [](https://www.expedia.ca/Dalhart-Hotels-Days-Inn-By-Wyndham-Dalhart.h27413.Hotel-Information) ![Indoor pool](https://images.trvl-media.com/lodging/2000000/1190000/1184000/1183905/0abb04c2.jpg?impolicy=fcrop&w=357&h=201&p=1&q=medium) ![Lobby](https://images.trvl-media.com/lodging/2000000/1190000/1184000/1183905/96870b4c.jpg?impolicy=fcrop&w=357&h=201&p=1&q=medium) ![Free daily buffet breakfast](https://images.trvl-media.com/lodging/2000000/1190000/1184000/1183905/cdb90461.jpg?impolicy=fcrop&w=357&h=201&p=1&q=medium) ![Sports facility](https://images.trvl-media.com/lodging/2000000/1190000/1184000/1183905/537bd66b.jpg?impolicy=fcrop&w=357&h=201&p=1&q=medium) ### Country Inn & Suites by Radisson, Amarillo I-40 West, TX [](https://www.expedia.ca/Amarillo-Hotels-Country-Inn-Suites-By-Radisson.h1183905.Hotel-Information) Amarillo 9.0/10 Wonderful (2437) "nice hotel, nice rooms and comfy beds " ![United States](https://a.travel-assets.com/egds/marks/flags/us.svg) Daniel CA $104 CA $119 total includes taxes & fees Jan 12 - Jan 13, 2026 [](https://www.expedia.ca/Amarillo-Hotels-Country-Inn-Suites-By-Radisson.h1183905.Hotel-Information) ![Free daily continental breakfast](https://images.trvl-media.com/lodging/1000000/930000/921300/921277/24a2609a.jpg?impolicy=fcrop&w=357&h=201&p=1&q=medium) ![Indoor pool](https://images.trvl-media.com/lodging/1000000/930000/921300/921277/dd66ab46.jpg?impolicy=fcrop&w=357&h=201&p=1&q=medium) ![Desk, laptop workspace, blackout drapes, iron/ironing board](https://images.trvl-media.com/lodging/1000000/930000/921300/921277/d3e39e7c.jpg?impolicy=fcrop&w=357&h=201&p=1&q=medium) ![Reception](https://images.trvl-media.com/lodging/1000000/930000/921300/921277/863b1cc9.jpg?impolicy=fcrop&w=357&h=201&p=1&q=medium) ### Spark by Hilton Dumas [](https://www.expedia.ca/Dumas-Hotels-INVISION-INN.h921277.Hotel-Information) Dumas 9.0/10 Wonderful (1008) "For a low-priced hotel, this is surprisingly nice! Nice interiors, comfortable rooms, quiet despite the highway just outside. Breakfast was sparse in comparison to more standard fare in other chains, but the savings were well worth the difference." ![United States](https://a.travel-assets.com/egds/marks/flags/us.svg) John CA $98 CA $111 total includes taxes & fees Jan 11 - Jan 12, 2026 [](https://www.expedia.ca/Dumas-Hotels-INVISION-INN.h921277.Hotel-Information) Lowest nightly price found within the past 24 hours based on a 1 night stay for 2 adults. Prices and availability subject to change. Additional terms may apply. [View all properties](https://expedia.ca/Hotel-Search?startDate=2025-12-31&endDate=2026-01-01®ionId=6058805&adults=2&travelerType=business_friendly&sort=RECOMMENDED&openPlayBack=true) ## Top Panhandle Plains Hotel Reviews ![Drury Inn & Suites Amarillo](https://images.trvl-media.com/lodging/2000000/1530000/1529800/1529725/887f87c2_y.jpg) ### Drury Inn & Suites Amarillo 10/10 Excellent "All good" [](https://expedia.ca/Amarillo-Hotels-Drury-Inn-Suites-Amarillo.h1529725.Hotel-Information) ![MCM Elegante Suites Abilene](https://images.trvl-media.com/lodging/1000000/10000/1900/1837/6730caae_y.jpg) ### MCM Elegante Suites Abilene 10/10 Excellent "Clean room friendly staff especially breakfast staff" [](https://expedia.ca/Abilene-Hotels-MCM-Elegante-Suites-Abilene.h1837.Hotel-Information) ![Wingate by Wyndham Lubbock near Texas Tech Univ. Medical Ctr](https://images.trvl-media.com/lodging/18000000/17190000/17180300/17180281/3d2a5d18_y.jpg) ### Wingate by Wyndham Lubbock near Texas Tech Univ. Medical Ctr 10/10 Excellent "Yeeessss " [](https://expedia.ca/Lubbock-Hotels-Wingate-By-Wyndham-Lubbock-Near-Texas-Tech-Univ-Medical-Ctr.h17180281.Hotel-Information) ![Days Inn & Suites by Wyndham Lubbock Medical Center](https://images.trvl-media.com/lodging/16000000/15920000/15914000/15913916/85a86121_y.jpg) ### Days Inn & Suites by Wyndham Lubbock Medical Center 10/10 Excellent "Great" [](https://expedia.ca/Lubbock-Hotels-Days-Inn-Suites-By-Wyndham-Lubbock-Medical-Center.h15913916.Hotel-Information) ![La Quinta Inn by Wyndham Amarillo Mid-City](https://images.trvl-media.com/lodging/1000000/20000/13800/13732/062462c6_y.jpg) ### La Quinta Inn by Wyndham Amarillo Mid-City 10/10 Excellent "Great place to get some sleep and was an amazing breakfast. " [](https://expedia.ca/Amarillo-Hotels-La-Quinta-Inn-By-Wyndham-Amarillo-Mid-City.h13732.Hotel-Information) ![Ashmore Inn and Suites](https://images.trvl-media.com/lodging/1000000/60000/51000/50901/0c494772_y.jpg) ### Ashmore Inn and Suites 10/10 Excellent "Great staff." [](https://expedia.ca/Lubbock-Hotels-Ashmore-Inn-And-Suites.h50901.Hotel-Information) ![Holiday Inn Express & Suites Amarillo West by IHG](https://images.trvl-media.com/lodging/5000000/4280000/4270900/4270804/02449019_y.jpg) ### Holiday Inn Express & Suites Amarillo West by IHG 10/10 Excellent "Friendly staff and clean and comfortable room. " [](https://expedia.ca/Amarillo-Hotels-Holiday-Inn-Express-Hotel-Suites-Amarillo-West.h4270804.Hotel-Information) ![Country Inn & Suites by Radisson, Amarillo I-40 West, TX](https://images.trvl-media.com/lodging/2000000/1190000/1184000/1183905/0abb04c2_y.jpg) ### Country Inn & Suites by Radisson, Amarillo I-40 West, TX 10/10 Excellent "Big lighted parking lot. Rooms clean and bed was very comfortable. " [](https://expedia.ca/Amarillo-Hotels-Country-Inn-Suites-By-Radisson.h1183905.Hotel-Information) ![La Quinta Inn & Suites by Wyndham Lubbock North](https://images.trvl-media.com/lodging/2000000/1550000/1546000/1545954/692e27e5_y.jpg) ### La Quinta Inn & Suites by Wyndham Lubbock North 10/10 Excellent "Very clean" [](https://expedia.ca/Lubbock-Hotels-La-Quinta-Inn-Suites-By-Wyndham-Lubbock-North.h1545954.Hotel-Information) ## Frequently asked questions ### How much do business-friendly hotels in Panhandle Plains cost? ### What are the best business-friendly hotels in Panhandle Plains? ### How many business-friendly hotels are there in Panhandle Plains? ### What are the best cheap business-friendly hotels in Panhandle Plains? ### What are the top business-friendly motels in Panhandle Plains? ### Are there any family-friendly hotels in Panhandle Plains that are also business friendly? ### Why book your business-friendly hotel in Panhandle Plains with Expedia? ### How can I find cheap business-friendly hotels in Panhandle Plains? ### What is there to do in Panhandle Plains near my business-friendly hotel? ## Explore a world of travel with Expedia - 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