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Featured Panama Boutique Hotels

See all 499 Hotels in Panama
Villa Palma Boutique Hotel

Villa Palma Boutique Hotel

Calle 1era, Panama City
4.0 out of 5.0
4.3 out of 5 (20 reviews)
Elegant boutique hotelHad zero problems with check in, check out, and overall it was a pleasant experience.
  9 Oct 2017

C$116

C$116
DeVille Hotel Boutique

DeVille Hotel Boutique

50 street and Beatriz M. De Cabal, Panama City
4.0 out of 5.0
4.2 out of 5 (103 reviews)
A tradition in PanamaI used to put visitors in this hotel a few years ago when living in Panama because it is a very convenient central location for the city in the banking district. It ran in the mid one hundreds per night back then. Imagine my surprise to find it online for basically one third the price for a return ...
  16 Oct 2017

C$57

C$57
Hotel Gatto Blanco & Rooftop Club

Hotel Gatto Blanco & Rooftop Club

Avenida B con Calle 8, Panama City
3.5 out of 5.0
3.1 out of 5 (35 reviews)
Nice hotel for those who like late nights to partyVery clean, very nice staff, however the rooftop bar above the hotel is VERY loud at night and unless you go to bed at 4am on the weekends, you will get little sleep from the noise upstairs. Try staying on the first floor for more silence, bring or ask for earplugs. Management did say that they are ...
  22 Aug 2017

C$86

C$86
Global Hotel Panama

Global Hotel Panama

Calle 54 Este y Samuel Lewis, Panama City
4.0 out of 5.0
4.6 out of 5 (47 reviews)
Excellent option in ObarrioSmall but charming hotel. Staff very friendly! clean rooms and everything working.... The bed is a bit hard but compensated with the selection of pillows. Breakfest not worth the pay but dinners very good!!
  16 Oct 2017

C$103

C$103
Los Establos Boutique Hotel

Los Establos Boutique Hotel

Jaramillo Arriba, Boquete
3.5 out of 5.0
4.2 out of 5 (6 reviews)
Our family stayed at Los Establos for 3 nights and enjoyed our stay. Clean, quiet and very friendly staff.
  5 Apr 2017

C$289

C$289
Playa Tortuga Hotel Beach And Resort

Playa Tortuga Hotel Beach And Resort

Camino A Playa Bluff Y P Creek, Bocas Del Toro
4.0 out of 5.0
3.5 out of 5 (82 reviews)
Beautiful placeMy experience is that it is a very beautiful place with crystal clear water, friendly people .. excellent weather. The hotel has warm rooms and really cozy beds for those who are going to enjoy life ... to rest and to know a place really made by the hand of God.
  24 Sep 2017

C$128

C$128
Hotel Casa Panamá

Hotel Casa Panamá

Avenida Eloy Alfaro y Calle 11, Panama City
4.0 out of 5.0
3.3 out of 5 (32 reviews)
Modern loft-type rooms, great locationGreat design (though maybe a bit too modern) of the hotel and rooms. AC is perfect as you will need this in Panama. Great location on the edge of Casco viejo. Walking is easy through Casco and you can also go the other way towards the city using the Cinta Costera walkway. Enjoy a small pool on the ...
  18 Aug 2017

C$74

C$74
Manrey Boutique Hotel

Manrey Boutique Hotel

Calle Uruguay y Calle 48, Panama City
4.5 out of 5.0
4.0 out of 5 (70 reviews)
Service is goodGreat location for night life. Several Discos and nice restruant walking distance.
  19 Oct 2015
Occidental Panamá City

Occidental Panamá City

Avenida 2da Sur, Obarrio, Bella Vista, Panama City
4.0 out of 5.0
4.0 out of 5 (234 reviews)
Perfect stayPerfect stay in Panama city. Hotel Occidental is the best for quality at a good price.
  8 Oct 2017

C$68

C$68
The Haven and Spa

The Haven and Spa

Avenida A Oeste, Bajo, Boquete
3.5 out of 5.0
4.3 out of 5 (49 reviews)
Overall excellent Overall excellent. Clean room. Grounds well kept. Well managed
  4 Feb 2017

C$118

C$118
Map

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Book a Panama Boutique Lodging that is Especially You

Arriving in Panama you'll discover that all your concerns are left behind and you can rest easy for the next several days. And you're not alone in thinking it is a nice idea to come to Panama, as this location has seen a large upsurge in travelers this past year. It should come as no shock that Panama is popular with travelers such as yourself, since it ranks in our top 100 of most visited vacation destinations. No matter where you may holiday, you always pack your one-of-a-kind self on your trip, and Expedia provides reservations at the most fashionable and distinctive boutique rooms in the city.

Petite Hotel with Enormous Personality

You'll love returning from a thrilling day of sightseeing in Panama and decompressing in a room that boasts inviting architectural designs and fabulous artwork. Further, these distinctive properties bring a bit of the spirit and vibe of Panama into your room, making your stay much more intimate. The majority of boutique hotels have qualities like:

  • A highly personalized service where they add thoughtful touches like fresh flowers.
  • A more exclusive stay, since boutique hotels commonly have fewer than 100 rooms.
  • A desirable address in the entertaining part of the city. You'll be steps from the city's most talked about attractions.
  • An idiosyncratic character that you will not be able to get in more sizable hotels, from individually crafted rooms to intimate bars, and thoughtful touches that make it feel like home.

Bask in Everything Panama Offers!

Panama has rooms to satisfy all types of budgets and preferences that create a visit extraordinary.

Book a Room with Views Inside and Out in Panama

If you need a stay in a Panama boutique hotel that will make you feel like a guest in a chic home, book soon, since everybody is as well. Luckily, Expedia has all the top listings on the most exceptional boutique properties. A remarkable stay is only a couple taps away!