Title: Book the Best BUSINESS Hotels in Panama Canal Zone in 2025 | Expedia.ca [Panama Canal Zone Travel Guide](https://expedia.ca/Panama-Canal-Zone.dx6222968)[Hotels in Panama Canal Zone](https://expedia.ca/Panama-Canal-Zone-Hotels.d6222968.Travel-Guide-Hotels)[Vacation Rentals in Panama Canal Zone](https://expedia.ca/Panama-Canal-Zone-Vacation-Rentals.d6222968.Travel-Guide-VacationRentals)[Flights to Panama Canal Zone](https://expedia.ca/Cheap-Flights-To-Panama-Canal-Zone.d6222968.Travel-Guide-Flights)[Panama Canal Zone Car Rentals](https://expedia.ca/Car-Rentals-In-Panama-Canal-Zone.d6222968.Car-Rental-Guide)[Panama Canal Zone Vacation Packages](https://expedia.ca/Panama-Canal-Zone.d6222968.Destination-Travel-Guides) ![Colon showing building ruins and a garden](https://a.travel-assets.com/findyours-php/viewfinder/images/res70/267000/267275-Colon.jpg?impolicy=fcrop&w=1200&h=500&q=medium) # Find Business Hotels in Panama Canal Zone ![](https://a.travel-assets.com/travel-assets-manager/pictogram-bex/light__calendar_shield.svg) ### Change your mind Book hotels with free cancellation ![](https://a.travel-assets.com/travel-assets-manager/pictogram-bex/light__deals.svg) ### Treat yourself Sign in to save 10% or more on thousands of hotels [Sign in](https://www.expedia.ca/login) ![](https://a.travel-assets.com/travel-assets-manager/pictogram-bex/light__bed.svg) ### Be picky Search almost a million properties worldwide ## Check availability on Panama Canal Zone Business Hotels Tonight [Oct 13 - Oct 14](https://www.expedia.ca/Hotel-Search?regionId=6222968&startDate=2025-10-13&endDate=2025-10-14&adults=2&travelerType=BUSINESS&rfrr=TG.LP.CheckPrices.Hotel&openPlayBack=true) Tomorrow [Oct 14 - Oct 15](https://www.expedia.ca/Hotel-Search?regionId=6222968&startDate=2025-10-14&endDate=2025-10-15&adults=2&travelerType=BUSINESS&rfrr=TG.LP.CheckPrices.Hotel&openPlayBack=true) This weekend [Oct 17 - Oct 19](https://www.expedia.ca/Hotel-Search?regionId=6222968&startDate=2025-10-17&endDate=2025-10-19&adults=2&travelerType=BUSINESS&rfrr=TG.LP.CheckPrices.Hotel&openPlayBack=true) Next weekend [Oct 24 - Oct 26](https://www.expedia.ca/Hotel-Search?regionId=6222968&startDate=2025-10-24&endDate=2025-10-26&adults=2&travelerType=BUSINESS&rfrr=TG.LP.CheckPrices.Hotel&openPlayBack=true) ## Top Panama Canal Zone Business Hotels ![2 outdoor pools, pool umbrellas, sun loungers](https://images.trvl-media.com/lodging/1000000/810000/809200/809149/23e8ad44.jpg?impolicy=fcrop&w=357&h=201&p=1&q=medium) ![Meeting facility](https://images.trvl-media.com/lodging/1000000/810000/809200/809149/b6d8aae1.jpg?impolicy=fcrop&w=357&h=201&p=1&q=medium) ![Exterior](https://images.trvl-media.com/lodging/1000000/810000/809200/809149/93c6a3dd.jpg?impolicy=fcrop&w=357&h=201&p=1&q=medium) ![Lounge](https://images.trvl-media.com/lodging/1000000/810000/809200/809149/dea447f2.jpg?impolicy=fcrop&w=357&h=201&p=1&q=medium) ### Radisson Hotel Panama Canal Amador 8.4/10 Very good (1001) "Very nice hotel!" CA $102 CA $113 total includes taxes & fees Nov 9 - Nov 10 [](https://www.expedia.ca/Amador-Hotels-Radisson-Hotel-Panama-Canal.h809149.Hotel-Information) ![Aerial view](https://images.trvl-media.com/lodging/1000000/440000/438200/438135/0d6dbc5b.jpg?impolicy=fcrop&w=357&h=201&p=1&q=medium) ![Lobby](https://images.trvl-media.com/lodging/1000000/440000/438200/438135/daf15c9c.jpg?impolicy=fcrop&w=357&h=201&p=1&q=medium) ![Lobby sitting area](https://images.trvl-media.com/lodging/1000000/440000/438200/438135/c7eb2b99.jpg?impolicy=fcrop&w=357&h=201&p=1&q=medium) ![View from room](https://images.trvl-media.com/lodging/1000000/440000/438200/438135/ae3567aa.jpg?impolicy=fcrop&w=357&h=201&p=1&q=medium) ### Gamboa Rainforest Reserve Colon 7.8/10 Good (645) "Nice, spacious, very comfortable room and bathroom. Balcony had beautiful scenic views. A/C could have worked a bit better but understandable due to the high heat and humidity of the rainforest. Highly recommend doing the boat ride to see and feed the monkeys. Great experience!" CA $142 CA $160 total includes taxes & fees Oct 21 - Oct 22 [](https://www.expedia.ca/Gamboa-Hotels-Gamboa-Rainforest-Reserve.h438135.Hotel-Information) ![Outdoor pool, pool umbrellas, sun loungers](https://images.trvl-media.com/lodging/3000000/2100000/2096400/2096355/6785cd9d.jpg?impolicy=fcrop&w=357&h=201&p=1&q=medium) ![Property amenity](https://images.trvl-media.com/lodging/3000000/2100000/2096400/2096355/a2f5a70d.jpg?impolicy=fcrop&w=357&h=201&p=1&q=medium) ![Coffee shop](https://images.trvl-media.com/lodging/3000000/2100000/2096400/2096355/404b7814.jpg?impolicy=fcrop&w=357&h=201&p=1&q=medium) ![Exterior](https://images.trvl-media.com/lodging/3000000/2100000/2096400/2096355/532b8393.jpg?impolicy=fcrop&w=357&h=201&p=1&q=medium) ### Holiday Inn Panama Canal by IHG Panama City 8.4/10 Very good (431) "Just good" CA $111 CA $122 total includes taxes & fees Nov 7 - Nov 8 [](https://www.expedia.ca/Panama-City-Hotels-Holiday-Inn-Panama-Canal.h2096355.Hotel-Information) ![Terrace/patio](https://images.trvl-media.com/lodging/7000000/6100000/6099300/6099287/b61be540.jpg?impolicy=fcrop&w=357&h=201&p=1&q=medium) ![Lobby](https://images.trvl-media.com/lodging/7000000/6100000/6099300/6099287/c617be5e.jpg?impolicy=fcrop&w=357&h=201&p=1&q=medium) ![Outdoor pool, open 7:00 AM to 8:00 PM, pool umbrellas](https://images.trvl-media.com/lodging/7000000/6100000/6099300/6099287/9eaa509a.jpg?impolicy=fcrop&w=357&h=201&p=1&q=medium) ![Lobby](https://images.trvl-media.com/lodging/7000000/6100000/6099300/6099287/38485558.jpg?impolicy=fcrop&w=357&h=201&p=1&q=medium) ### Marriott Panama Hotel Panama City 9.0/10 Wonderful (1002) "Excellent location next to Albrook Mall. Lots of good shopping and variety of food choices. " CA $188 CA $207 total includes taxes & fees Oct 18 - Oct 19 [](https://www.expedia.ca/Panama-City-Hotels-Marriott-Panama-Hotel.h6099287.Hotel-Information) ![Terrace/patio](https://images.trvl-media.com/lodging/4000000/3010000/3006200/3006144/a96760ad.jpg?impolicy=fcrop&w=357&h=201&p=1&q=medium) ![View from room](https://images.trvl-media.com/lodging/4000000/3010000/3006200/3006144/a14af686.jpg?impolicy=fcrop&w=357&h=201&p=1&q=medium) ![Terrace/patio](https://images.trvl-media.com/lodging/4000000/3010000/3006200/3006144/c22cbe98.jpg?impolicy=fcrop&w=357&h=201&p=1&q=medium) ![Lobby](https://images.trvl-media.com/lodging/4000000/3010000/3006200/3006144/67eeecec.jpg?impolicy=fcrop&w=357&h=201&p=1&q=medium) ### Summit Rainforest & Golf Resort Panama City 8.4/10 Very good (1002) "I had a wonderful stay! The breakfast was amazing, and the staff were very friendly and welcoming. The hotel’s location, surrounded by nature, made it easy to truly unplug and relax. Perfect spot for a peaceful getaway." CA $102 CA $112 total includes taxes & fees Oct 15 - Oct 16 [](https://www.expedia.ca/Ancon-Hotels-Summit-Rainforest-Golf-Resort.h3006144.Hotel-Information) ![Outdoor pool, open 6 AM to 8 PM, sun loungers](https://images.trvl-media.com/lodging/3000000/2150000/2147400/2147349/de56591c.jpg?impolicy=fcrop&w=357&h=201&p=1&q=medium) ![Reception](https://images.trvl-media.com/lodging/3000000/2150000/2147400/2147349/b883cd02.jpg?impolicy=fcrop&w=357&h=201&p=1&q=medium) ![Executive Room, 1 King Bed, Non Smoking](https://images.trvl-media.com/lodging/3000000/2150000/2147400/2147349/c6ab4ca0.jpg?impolicy=fcrop&w=357&h=201&p=1&q=medium) ![Bar (on property)](https://images.trvl-media.com/lodging/3000000/2150000/2147400/2147349/e77a4c37.jpg?impolicy=fcrop&w=357&h=201&p=1&q=medium) ### Radisson Colon 2,000 Hotel & Casino Barrio Sur 8.2/10 Very good (793) "Decent hotel close to the free zone " CA $123 CA $135 total includes taxes & fees Nov 1 - Nov 2 [](https://www.expedia.ca/Colon-Hotels-Radisson-Colon-2.h2147349.Hotel-Information) ![Outdoor pool, open 9:30 AM to 7:00 PM, sun loungers](https://images.trvl-media.com/lodging/67000000/66730000/66723000/66722954/84f0a319.jpg?impolicy=fcrop&w=357&h=201&p=1&q=medium) ![Restaurant](https://images.trvl-media.com/lodging/67000000/66730000/66723000/66722954/4502bc4e.jpg?impolicy=fcrop&w=357&h=201&p=1&q=medium) ![Lobby](https://images.trvl-media.com/lodging/67000000/66730000/66723000/66722954/ac5d93a5.jpg?impolicy=fcrop&w=357&h=201&p=1&q=medium) ![Lobby lounge](https://images.trvl-media.com/lodging/67000000/66730000/66723000/66722954/f2241113.jpg?impolicy=fcrop&w=357&h=201&p=1&q=medium) ### SAND DIAMOND HOTEL Colon 8.4/10 Very good (189) "Great staff" CA $167 CA $183 total includes taxes & fees Oct 14 - Oct 15 [](https://www.expedia.ca/Colon-Hotels-SAND-DIAMOND-HOTEL.h66722954.Hotel-Information) ![Front of property](https://images.trvl-media.com/lodging/24000000/23810000/23809900/23809852/5cf5cc1f.jpg?impolicy=fcrop&w=357&h=201&p=1&q=medium) ![Classic Triple Room](https://images.trvl-media.com/lodging/24000000/23810000/23809900/23809852/9c1f86f1.jpg?impolicy=fcrop&w=357&h=201&p=1&q=medium) ![Reception](https://images.trvl-media.com/lodging/24000000/23810000/23809900/23809852/5426f845.jpg?impolicy=fcrop&w=357&h=201&p=1&q=medium) ![Point of interest](https://images.trvl-media.com/lodging/24000000/23810000/23809900/23809852/e9b037a4.jpg?impolicy=fcrop&w=357&h=201&p=1&q=medium) ### La Cubana Hotel & Residencial Cristobal 8.0/10 Very good (100) "Good option for budge friendly while shopping at zona libre! Must have a car, they offer free parking service, staff and rooms are good!" CA $42 CA $46 total includes taxes & fees Oct 14 - Oct 15 [](https://www.expedia.ca/Colon-Hotels-La-Cubana-Hotel-Residencial.h23809852.Hotel-Information) ![3 outdoor pools, pool umbrellas, sun loungers](https://images.trvl-media.com/lodging/5000000/4670000/4668700/4668643/f767a768.jpg?impolicy=fcrop&w=357&h=201&p=1&q=medium) ![2 bars/lounges, 2 poolside bars, swim-up bar](https://images.trvl-media.com/lodging/5000000/4670000/4668700/4668643/a12fa485.jpg?impolicy=fcrop&w=357&h=201&p=1&q=medium) ![3 outdoor pools, pool umbrellas, sun loungers](https://images.trvl-media.com/lodging/5000000/4670000/4668700/4668643/6d441b5e.jpg?impolicy=fcrop&w=357&h=201&p=1&q=medium) ![View from property](https://images.trvl-media.com/lodging/5000000/4670000/4668700/4668643/d8a24106.jpg?impolicy=fcrop&w=357&h=201&p=1&q=medium) ### The Westin Playa Bonita Panama Veracruz 8.0/10 Very good (1003) "Had a great stay! The room was clean, comfortable, and exactly what we needed. The staff was super friendly and helpful, and the location was perfect. Everything went smoothly from check-in to check-out — would definitely stay here again!" CA $233 CA $256 total includes taxes & fees Nov 9 - Nov 10 [](https://www.expedia.ca/Panama-City-Hotels-The-Westin-Playa-Bonita-Panama.h4668643.Hotel-Information) ![Suite, 1 Bedroom, Non Smoking, Golf View (Terrace)](https://images.trvl-media.com/lodging/21000000/20960000/20958600/20958573/d80494b9.jpg?impolicy=fcrop&w=357&h=201&p=1&q=medium) ![Bar (on property)](https://images.trvl-media.com/lodging/21000000/20960000/20958600/20958573/e5856e04.jpg?impolicy=fcrop&w=357&h=201&p=1&q=medium) ![View from room](https://images.trvl-media.com/lodging/21000000/20960000/20958600/20958573/c77947e6.jpg?impolicy=fcrop&w=357&h=201&p=1&q=medium) ![Exterior](https://images.trvl-media.com/lodging/21000000/20960000/20958600/20958573/2a51fa85.jpg?impolicy=fcrop&w=357&h=201&p=1&q=medium) ### The Santa Maria, A Luxury Collection Hotel & Golf Resort, Panama City Juan Diaz 9.6/10 Exceptional (616) "Amazing property with top service professionals in all departments across the resort. Enjoyed every single moment of my stay. Recommended to anyone traveling to Panama & wants a bit of luxury with a hint of hospitality." CA $303 CA $334 total includes taxes & fees Nov 9 - Nov 10 [](https://www.expedia.ca/Panama-City-Hotels-The-Santa-Maria.h20958573.Hotel-Information) Lowest nightly price found within the past 24 hours based on a 1 night stay for 2 adults. Prices and availability subject to change. Additional terms may apply. [View all properties](https://expedia.ca/Hotel-Search?startDate=2025-10-27&endDate=2025-10-28®ionId=6222968&adults=2&travelerType=business_friendly&sort=RECOMMENDED&openPlayBack=true) ## Top Panama Canal Zone Hotel Reviews ![Crowne Plaza Panama Airport by IHG](//images.trvl-media.com/lodging/9000000/8840000/8836200/8836117/877d081d_y.jpg) ### Crowne Plaza Panama Airport by IHG 10/10 Excellent "always take a cab..easy and no wait" [](https://expedia.ca/Tocumen-Hotels-Crowne-Plaza-Panama-Airport.h8836117.Hotel-Information) ![The Westin Playa Bonita Panama](//images.trvl-media.com/lodging/5000000/4670000/4668700/4668643/f767a768_y.jpg) ### The Westin Playa Bonita Panama 10/10 Excellent "Hotel and facilities were outstanding. Staff was helpful and friendly. Food was fresh and delicious!! I will definitely stay again. " [](https://expedia.ca/Panama-City-Hotels-The-Westin-Playa-Bonita-Panama.h4668643.Hotel-Information) ![Decapolis Hotel Panama City](//images.trvl-media.com/lodging/2000000/1090000/1082800/1082793/067e7d25_y.jpg) ### Decapolis Hotel Panama City 10/10 Excellent "Very nice Hotel " [](https://expedia.ca/Panama-City-Hotels-Decapolis-Hotel-Panama-City.h1082793.Hotel-Information) ![Hotel Riu Plaza Panama](//images.trvl-media.com/lodging/4000000/3910000/3900400/3900395/1eaf88f5_y.jpg) ### Hotel Riu Plaza Panama 10/10 Excellent "I haven't been by the pool" [](https://expedia.ca/Panama-City-Hotels-Hotel-Riu-Plaza-Panama.h3900395.Hotel-Information) ![The Executive Hotel](//images.trvl-media.com/lodging/1000000/530000/522100/522086/493046b7_y.jpg) ### The Executive Hotel 10/10 Excellent "An amazing hotel, I will do a repeat in the near future 10/10" [](https://expedia.ca/Panama-City-Hotels-The-Executive-Hotel.h522086.Hotel-Information) ![Central Hotel Panama Casco Viejo](//images.trvl-media.com/lodging/16000000/15690000/15683600/15683502/3165768f_y.jpg) ### Central Hotel Panama Casco Viejo 10/10 Excellent "Excellent " [](https://expedia.ca/Panama-City-Hotels-Central-Hotel-Panama-Casco-Viejo.h15683502.Hotel-Information) ![Principe Hotel and Suites](//images.trvl-media.com/lodging/8000000/7460000/7451800/7451703/2baee2b4_y.jpg) ### Principe Hotel and Suites 10/10 Excellent "The room was excellent very clean" [](https://expedia.ca/Panama-City-Hotels-Principe-Hotel-And-Suites.h7451703.Hotel-Information) ![JW Marriott Panama](//images.trvl-media.com/lodging/5000000/4110000/4109200/4109123/fb42dbf6_y.jpg) ### JW Marriott Panama 10/10 Excellent "The experience was very beautiful from the room to the views at the pool. Customer service excellent and respectful and courteous. They made my birthday wonderful." [](https://expedia.ca/Panama-City-Hotels-JW-Marriott-Panama.h4109123.Hotel-Information) ![Dreams Playa Bonita Panama - All Inclusive](//images.trvl-media.com/lodging/13000000/12450000/12445600/12445554/7c338453_y.jpg) ### Dreams Playa Bonita Panama - All Inclusive 10/10 Excellent "From greeting at the front, helpful checkin, great service in restaurants to pickup of our luggage when leaving, fabulous" [](https://expedia.ca/Panama-City-Hotels-Dreams-Playa-Bonita-Panama.h12445554.Hotel-Information)