Title: Book the Best BUSINESS Hotels in Panama Canal Zone in 2025 | Expedia.ca [Panama Canal Zone Travel Guide](https://expedia.ca/Panama-Canal-Zone.dx6222968)[Hotels in Panama Canal Zone](https://expedia.ca/Panama-Canal-Zone-Hotels.d6222968.Travel-Guide-Hotels)[Vacation Rentals in Panama Canal Zone](https://expedia.ca/Panama-Canal-Zone-Vacation-Rentals.d6222968.Travel-Guide-VacationRentals)[Flights to Panama Canal Zone](https://expedia.ca/Cheap-Flights-To-Panama-Canal-Zone.d6222968.Travel-Guide-Flights)[Panama Canal Zone Car Rentals](https://expedia.ca/Car-Rentals-In-Panama-Canal-Zone.d6222968.Car-Rental-Guide)[Panama Canal Zone Vacation Packages](https://expedia.ca/Panama-Canal-Zone.d6222968.Destination-Travel-Guides) ![Colon showing building ruins and a garden](https://a.travel-assets.com/findyours-php/viewfinder/images/res70/267000/267275-Colon.jpg?impolicy=fcrop&w=1200&h=500&q=medium) # Find Business Hotels in Panama Canal Zone ![](https://a.travel-assets.com/travel-assets-manager/pictogram-bex/light__calendar_shield.svg) ### Change your mind Book hotels with free cancellation ![](https://a.travel-assets.com/travel-assets-manager/pictogram-bex/light__deals.svg) ### Treat yourself Sign in to save 10% or more on thousands of hotels [Sign in](https://www.expedia.ca/login) ![](https://a.travel-assets.com/travel-assets-manager/pictogram-bex/light__bed.svg) ### Be picky Search almost a million properties worldwide ## Check availability on Panama Canal Zone Business Hotels Tonight [Oct 29 - Oct 30](https://www.expedia.ca/Hotel-Search?regionId=6222968&startDate=2025-10-29&endDate=2025-10-30&adults=2&rfrr=TG.LP.CheckPrices.Hotel&openPlayBack=true&travelerType=business_friendly) Tomorrow [Oct 30 - Oct 31](https://www.expedia.ca/Hotel-Search?regionId=6222968&startDate=2025-10-30&endDate=2025-10-31&adults=2&rfrr=TG.LP.CheckPrices.Hotel&openPlayBack=true&travelerType=business_friendly) This weekend [Oct 31 - Nov 2](https://www.expedia.ca/Hotel-Search?regionId=6222968&startDate=2025-10-31&endDate=2025-11-02&adults=2&rfrr=TG.LP.CheckPrices.Hotel&openPlayBack=true&travelerType=business_friendly) Next weekend [Nov 7 - Nov 9](https://www.expedia.ca/Hotel-Search?regionId=6222968&startDate=2025-11-07&endDate=2025-11-09&adults=2&rfrr=TG.LP.CheckPrices.Hotel&openPlayBack=true&travelerType=business_friendly) ## Top Panama Canal Zone Business Hotels ![2 outdoor pools, pool umbrellas, sun loungers](https://images.trvl-media.com/lodging/1000000/810000/809200/809149/23e8ad44.jpg?impolicy=fcrop&w=357&h=201&p=1&q=medium) ![Exterior](https://images.trvl-media.com/lodging/1000000/810000/809200/809149/93c6a3dd.jpg?impolicy=fcrop&w=357&h=201&p=1&q=medium) ![2 restaurants, lunch, dinner served; American cuisine](https://images.trvl-media.com/lodging/1000000/810000/809200/809149/53267d7d.jpg?impolicy=fcrop&w=357&h=201&p=1&q=medium) ![Meeting facility](https://images.trvl-media.com/lodging/1000000/810000/809200/809149/b6d8aae1.jpg?impolicy=fcrop&w=357&h=201&p=1&q=medium) ### Radisson Hotel Panama Canal Amador 8.4/10 Very good (1006) "Very nice hotel!" ![United States](https://a.travel-assets.com/egds/marks/flags/us.svg) Patricia CA $97 CA $107 total includes taxes & fees Nov 4 - Nov 5 [](https://www.expedia.ca/Amador-Hotels-Radisson-Hotel-Panama-Canal.h809149.Hotel-Information) ![Aerial view](https://images.trvl-media.com/lodging/1000000/440000/438200/438135/0d6dbc5b.jpg?impolicy=fcrop&w=357&h=201&p=1&q=medium) ![View from room](https://images.trvl-media.com/lodging/1000000/440000/438200/438135/ae3567aa.jpg?impolicy=fcrop&w=357&h=201&p=1&q=medium) ![Outdoor banquet area](https://images.trvl-media.com/lodging/1000000/440000/438200/438135/be207e74.jpg?impolicy=fcrop&w=357&h=201&p=1&q=medium) ![Lobby sitting area](https://images.trvl-media.com/lodging/1000000/440000/438200/438135/c7eb2b99.jpg?impolicy=fcrop&w=357&h=201&p=1&q=medium) ### Gamboa Rainforest Reserve Colon 7.8/10 Good (649) "We had a lovely stay, the views and tranquility of the place was my favorite part." ![United States](https://a.travel-assets.com/egds/marks/flags/us.svg) Rebecca CA $138 CA $155 total includes taxes & fees Oct 30 - Oct 31 [](https://www.expedia.ca/Gamboa-Hotels-Gamboa-Rainforest-Reserve.h438135.Hotel-Information) ![Terrace/patio](https://images.trvl-media.com/lodging/7000000/6100000/6099300/6099287/b61be540.jpg?impolicy=fcrop&w=357&h=201&p=1&q=medium) ![Lobby](https://images.trvl-media.com/lodging/7000000/6100000/6099300/6099287/38485558.jpg?impolicy=fcrop&w=357&h=201&p=1&q=medium) ![Lobby](https://images.trvl-media.com/lodging/7000000/6100000/6099300/6099287/c617be5e.jpg?impolicy=fcrop&w=357&h=201&p=1&q=medium) ![Exterior](https://images.trvl-media.com/lodging/7000000/6100000/6099300/6099287/e3f1253f.jpg?impolicy=fcrop&w=357&h=201&p=1&q=medium) ### Marriott Panama Hotel Panama City 9.0/10 Wonderful (1008) "The staff is hospitable and friendly " ![United States](https://a.travel-assets.com/egds/marks/flags/us.svg) BIBI FARANAZ CA $187 CA $206 total includes taxes & fees Nov 1 - Nov 2 [](https://www.expedia.ca/Panama-City-Hotels-Marriott-Panama-Hotel.h6099287.Hotel-Information) ![Terrace/patio](https://images.trvl-media.com/lodging/4000000/3010000/3006200/3006144/a96760ad.jpg?impolicy=fcrop&w=357&h=201&p=1&q=medium) ![View from room](https://images.trvl-media.com/lodging/4000000/3010000/3006200/3006144/a14af686.jpg?impolicy=fcrop&w=357&h=201&p=1&q=medium) ![Aerial view](https://images.trvl-media.com/lodging/4000000/3010000/3006200/3006144/b19e9542.jpg?impolicy=fcrop&w=357&h=201&p=1&q=medium) ![Lobby](https://images.trvl-media.com/lodging/4000000/3010000/3006200/3006144/67eeecec.jpg?impolicy=fcrop&w=357&h=201&p=1&q=medium) ### Summit Rainforest & Golf Resort Panama City 8.4/10 Very good (1002) "I had a wonderful stay! The breakfast was amazing, and the staff were very friendly and welcoming. The hotel’s location, surrounded by nature, made it easy to truly unplug and relax. Perfect spot for a peaceful getaway." ![United States](https://a.travel-assets.com/egds/marks/flags/us.svg) Henry CA $100 CA $109 total includes taxes & fees Oct 30 - Oct 31 [](https://www.expedia.ca/Ancon-Hotels-Summit-Rainforest-Golf-Resort.h3006144.Hotel-Information) ![Outdoor pool, pool umbrellas, sun loungers](https://images.trvl-media.com/lodging/3000000/2100000/2096400/2096355/6785cd9d.jpg?impolicy=fcrop&w=357&h=201&p=1&q=medium) ![Reception](https://images.trvl-media.com/lodging/3000000/2100000/2096400/2096355/6b71f77f.jpg?impolicy=fcrop&w=357&h=201&p=1&q=medium) ![Exterior](https://images.trvl-media.com/lodging/3000000/2100000/2096400/2096355/532b8393.jpg?impolicy=fcrop&w=357&h=201&p=1&q=medium) ![Coffee shop](https://images.trvl-media.com/lodging/3000000/2100000/2096400/2096355/404b7814.jpg?impolicy=fcrop&w=357&h=201&p=1&q=medium) ### Holiday Inn Panama Canal by IHG Panama City 8.4/10 Very good (433) "Breakfast bara" ![United States](https://a.travel-assets.com/egds/marks/flags/us.svg) Jason CA $109 CA $120 total includes taxes & fees Nov 7 - Nov 8 [](https://www.expedia.ca/Panama-City-Hotels-Holiday-Inn-Panama-Canal.h2096355.Hotel-Information) ![Outdoor pool, open 9:30 AM to 7:00 PM, sun loungers](https://images.trvl-media.com/lodging/67000000/66730000/66723000/66722954/84f0a319.jpg?impolicy=fcrop&w=357&h=201&p=1&q=medium) ![Restaurant](https://images.trvl-media.com/lodging/67000000/66730000/66723000/66722954/4502bc4e.jpg?impolicy=fcrop&w=357&h=201&p=1&q=medium) ![Lobby lounge](https://images.trvl-media.com/lodging/67000000/66730000/66723000/66722954/f2241113.jpg?impolicy=fcrop&w=357&h=201&p=1&q=medium) ![Lobby](https://images.trvl-media.com/lodging/67000000/66730000/66723000/66722954/ac5d93a5.jpg?impolicy=fcrop&w=357&h=201&p=1&q=medium) ### SAND DIAMOND HOTEL Colon 8.4/10 Very good (197) "Great staff" ![United States](https://a.travel-assets.com/egds/marks/flags/us.svg) Robert LahMar CA $166 CA $183 total includes taxes & fees Oct 30 - Oct 31 [](https://www.expedia.ca/Colon-Hotels-SAND-DIAMOND-HOTEL.h66722954.Hotel-Information) ![Front of property](https://images.trvl-media.com/lodging/24000000/23810000/23809900/23809852/5cf5cc1f.jpg?impolicy=fcrop&w=357&h=201&p=1&q=medium) ![Point of interest](https://images.trvl-media.com/lodging/24000000/23810000/23809900/23809852/e9b037a4.jpg?impolicy=fcrop&w=357&h=201&p=1&q=medium) ![Reception](https://images.trvl-media.com/lodging/24000000/23810000/23809900/23809852/a5048168.jpg?impolicy=fcrop&w=357&h=201&p=1&q=medium) ![Classic Triple Room](https://images.trvl-media.com/lodging/24000000/23810000/23809900/23809852/9c1f86f1.jpg?impolicy=fcrop&w=357&h=201&p=1&q=medium) ### La Cubana Hotel & Residencial Cristobal 8.0/10 Very good (104) "Easy access to colon libre zone" ![United States](https://a.travel-assets.com/egds/marks/flags/us.svg) Everal CA $41 CA $46 total includes taxes & fees Oct 30 - Oct 31 [](https://www.expedia.ca/Colon-Hotels-La-Cubana-Hotel-Residencial.h23809852.Hotel-Information) ![Outdoor pool, open 6 AM to 8 PM, sun loungers](https://images.trvl-media.com/lodging/3000000/2150000/2147400/2147349/de56591c.jpg?impolicy=fcrop&w=357&h=201&p=1&q=medium) ![Reception](https://images.trvl-media.com/lodging/3000000/2150000/2147400/2147349/b883cd02.jpg?impolicy=fcrop&w=357&h=201&p=1&q=medium) ![1 King Bed, Superior Room, Breakfast Included | Beach/ocean view](https://images.trvl-media.com/lodging/3000000/2150000/2147400/2147349/c5fb33f0.jpg?impolicy=fcrop&w=357&h=201&p=1&q=medium) ![Executive Room, 1 King Bed, Non Smoking](https://images.trvl-media.com/lodging/3000000/2150000/2147400/2147349/c6ab4ca0.jpg?impolicy=fcrop&w=357&h=201&p=1&q=medium) ### Radisson Colon 2,000 Hotel & Casino Barrio Sur 8.2/10 Very good (797) "Staff was great room was clean" ![United States](https://a.travel-assets.com/egds/marks/flags/us.svg) Bridgett CA $122 CA $135 total includes taxes & fees Nov 15 - Nov 16 [](https://www.expedia.ca/Colon-Hotels-Radisson-Colon-2.h2147349.Hotel-Information) ![Suite, 1 Bedroom, Non Smoking, Golf View (Terrace)](https://images.trvl-media.com/lodging/21000000/20960000/20958600/20958573/d80494b9.jpg?impolicy=fcrop&w=357&h=201&p=1&q=medium) ![Bar (on property)](https://images.trvl-media.com/lodging/21000000/20960000/20958600/20958573/e5856e04.jpg?impolicy=fcrop&w=357&h=201&p=1&q=medium) ![View from room](https://images.trvl-media.com/lodging/21000000/20960000/20958600/20958573/c77947e6.jpg?impolicy=fcrop&w=357&h=201&p=1&q=medium) ![Exterior](https://images.trvl-media.com/lodging/21000000/20960000/20958600/20958573/2a51fa85.jpg?impolicy=fcrop&w=357&h=201&p=1&q=medium) ### The Santa Maria, A Luxury Collection Hotel & Golf Resort, Panama City Juan Diaz 9.6/10 Exceptional (620) "The staff were fantastic. The service was great. " ![United States](https://a.travel-assets.com/egds/marks/flags/us.svg) SANDRO CA $287 CA $316 total includes taxes & fees Nov 23 - Nov 24 [](https://www.expedia.ca/Panama-City-Hotels-The-Santa-Maria.h20958573.Hotel-Information) ![3 outdoor pools, pool umbrellas, sun loungers](https://images.trvl-media.com/lodging/5000000/4670000/4668700/4668643/6d441b5e.jpg?impolicy=fcrop&w=357&h=201&p=1&q=medium) ![Private beach, sun loungers, beach umbrellas, beach towels](https://images.trvl-media.com/lodging/5000000/4670000/4668700/4668643/e679a1c4.jpg?impolicy=fcrop&w=357&h=201&p=1&q=medium) ![3 outdoor pools, pool umbrellas, sun loungers](https://images.trvl-media.com/lodging/5000000/4670000/4668700/4668643/0e5b4d5c.jpg?impolicy=fcrop&w=357&h=201&p=1&q=medium) ![View from property](https://images.trvl-media.com/lodging/5000000/4670000/4668700/4668643/d8a24106.jpg?impolicy=fcrop&w=357&h=201&p=1&q=medium) ### The Westin Playa Bonita Panama Veracruz 8.0/10 Very good (1005) "Only here for a short stay, but enjoyed the facilities and staff!" ![Canada](https://a.travel-assets.com/egds/marks/flags/ca.svg) Leona CA $232 CA $255 total includes taxes & fees Nov 17 - Nov 18 [](https://www.expedia.ca/Panama-City-Hotels-The-Westin-Playa-Bonita-Panama.h4668643.Hotel-Information) Lowest nightly price found within the past 24 hours based on a 1 night stay for 2 adults. Prices and availability subject to change. Additional terms may apply. [View all properties](https://expedia.ca/Hotel-Search?startDate=2025-11-12&endDate=2025-11-13®ionId=6222968&adults=2&travelerType=business_friendly&sort=RECOMMENDED&openPlayBack=true) ## Top Panama Canal Zone Hotel Reviews ![Central Hotel Panama Casco Viejo](//images.trvl-media.com/lodging/16000000/15690000/15683600/15683502/3165768f_y.jpg) ### Central Hotel Panama Casco Viejo 10/10 Excellent "Staffs were wonderful." [](https://expedia.ca/Panama-City-Hotels-Central-Hotel-Panama-Casco-Viejo.h15683502.Hotel-Information) ![Crowne Plaza Panama Airport by IHG](//images.trvl-media.com/lodging/9000000/8840000/8836200/8836117/877d081d_y.jpg) ### Crowne Plaza Panama Airport by IHG 10/10 Excellent "It was a nice property" [](https://expedia.ca/Tocumen-Hotels-Crowne-Plaza-Panama-Airport.h8836117.Hotel-Information) ![Hotel Riu Plaza Panama](//images.trvl-media.com/lodging/4000000/3910000/3900400/3900395/1eaf88f5_y.jpg) ### Hotel Riu Plaza Panama 10/10 Excellent "The place was clean n always fresh , definitely my place to go whenever I come back to Panama. Love every bit of my stay " [](https://expedia.ca/Panama-City-Hotels-Hotel-Riu-Plaza-Panama.h3900395.Hotel-Information) ![JW Marriott Panama](//images.trvl-media.com/lodging/5000000/4110000/4109200/4109123/fb42dbf6_y.jpg) ### JW Marriott Panama 10/10 Excellent "The rooms were amazing " [](https://expedia.ca/Panama-City-Hotels-JW-Marriott-Panama.h4109123.Hotel-Information) ![Novotel Panama City](//images.trvl-media.com/lodging/8000000/7060000/7050600/7050512/aad97f9d_y.jpg) ### Novotel Panama City 10/10 Excellent "Nice Place and Pleasant momments" [](https://expedia.ca/Panama-City-Hotels-Novotel-Panama-City.h7050512.Hotel-Information) ![Radisson Hotel Panama Canal](//images.trvl-media.com/lodging/1000000/810000/809200/809149/23e8ad44_y.jpg) ### Radisson Hotel Panama Canal 10/10 Excellent "Superb customer service Ivonne Carrasco " [](https://expedia.ca/Amador-Hotels-Radisson-Hotel-Panama-Canal.h809149.Hotel-Information) ![The Executive Hotel](//images.trvl-media.com/lodging/1000000/530000/522100/522086/493046b7_y.jpg) ### The Executive Hotel 10/10 Excellent "." [](https://expedia.ca/Panama-City-Hotels-The-Executive-Hotel.h522086.Hotel-Information) ![Principe Hotel and Suites](//images.trvl-media.com/lodging/8000000/7460000/7451800/7451703/2baee2b4_y.jpg) ### Principe Hotel and Suites 10/10 Excellent "Good stay for 1 night" [](https://expedia.ca/Panama-City-Hotels-Principe-Hotel-And-Suites.h7451703.Hotel-Information) ![The Westin Playa Bonita Panama](//images.trvl-media.com/lodging/5000000/4670000/4668700/4668643/f767a768_y.jpg) ### The Westin Playa Bonita Panama 10/10 Excellent "Staff was very nice and helpful." [](https://expedia.ca/Panama-City-Hotels-The-Westin-Playa-Bonita-Panama.h4668643.Hotel-Information)