Title: Book the Best BUSINESS Hotels in Palisade in 2026 | Expedia.ca [Hotels in Palisade](https://expedia.ca/Palisade-Hotels.d143097.Travel-Guide-Hotels)[Vacation Rentals in Palisade](https://expedia.ca/Palisade-Vacation-Rentals.d143097.Travel-Guide-VacationRentals)[Palisade Car Rentals](https://expedia.ca/Car-Rentals-In-Palisade.d143097.Car-Rental-Guide)[Palisade Vacation Packages](https://expedia.ca/Palisade.d143097.Destination-Travel-Guides) ![Springtime in the Palisade Colorado. The peach orchards create a sea of pink blooms in the valley!](https://images.trvl-media.com/place/143097/da675963-f98f-44fd-b07c-1630312893e4.jpg?impolicy=fcrop&w=1200&h=500&q=medium) Photo by Teri Virbickis ![](https://images.trvl-media.com/place/143097/da675963-f98f-44fd-b07c-1630312893e4.jpg?impolicy=fcrop&w=1200&h=500&q=medium) - ![](https://a.travel-assets.com/travel-assets-manager/pictogram-bex/light__calendar_shield.svg) ### Change your mind Book hotels with free cancellation - ![](https://a.travel-assets.com/travel-assets-manager/pictogram-bex/light__deals.svg) ### Treat yourself Sign in to save 10% or more on thousands of hotels [Sign in](https://www.expedia.ca/login) - ![](https://a.travel-assets.com/travel-assets-manager/pictogram-bex/light__bed.svg) ### Be picky Search almost a million properties worldwide ## Check availability on Palisade Business Hotels Tonight [Jan 23 - Jan 24](https://www.expedia.ca/Hotel-Search?regionId=143097&startDate=2026-01-23&endDate=2026-01-24&adults=2&rfrr=TG.LP.CheckPrices.Hotel&openPlayBack=true&travelerType=business_friendly) Tomorrow [Jan 24 - Jan 25](https://www.expedia.ca/Hotel-Search?regionId=143097&startDate=2026-01-24&endDate=2026-01-25&adults=2&rfrr=TG.LP.CheckPrices.Hotel&openPlayBack=true&travelerType=business_friendly) This weekend [Jan 23 - Jan 25](https://www.expedia.ca/Hotel-Search?regionId=143097&startDate=2026-01-23&endDate=2026-01-25&adults=2&rfrr=TG.LP.CheckPrices.Hotel&openPlayBack=true&travelerType=business_friendly) Next weekend [Jan 30 - Feb 1](https://www.expedia.ca/Hotel-Search?regionId=143097&startDate=2026-01-30&endDate=2026-02-01&adults=2&rfrr=TG.LP.CheckPrices.Hotel&openPlayBack=true&travelerType=business_friendly) ## Our top choices for Palisade business-friendly hotels ![Seasonal outdoor pool, pool umbrellas](https://images.trvl-media.com/lodging/3000000/2110000/2108700/2108693/311fff4c.jpg?impolicy=fcrop&w=357&h=201&p=1&q=medium) ![Exterior](https://images.trvl-media.com/lodging/3000000/2110000/2108700/2108693/w3000h2022x0y2-11965b2e.jpg?impolicy=fcrop&w=357&h=201&p=1&q=medium) ![Meeting facility](https://images.trvl-media.com/lodging/3000000/2110000/2108700/2108693/7a2cdfb2.jpg?impolicy=fcrop&w=357&h=201&p=1&q=medium) ![Exterior](https://images.trvl-media.com/lodging/3000000/2110000/2108700/2108693/2e7baa84.jpg?impolicy=fcrop&w=357&h=201&p=1&q=medium) ### Wine Country Inn Palisade [](https://www.expedia.ca/Grand-Junction-Hotels-Wine-Country-Inn-Palisade.h2108693.Hotel-Information) Palisade 9.6/10 Exceptional (1,002 reviews) "Beautiful property, great breakfast!" ![United States](https://a.travel-assets.com/egds/marks/flags/us.svg) Amy [](https://www.expedia.ca/Grand-Junction-Hotels-Wine-Country-Inn-Palisade.h2108693.Hotel-Information) ![Dining](https://images.trvl-media.com/lodging/1000000/90000/84500/84495/f5063403.jpg?impolicy=fcrop&w=357&h=201&p=1&q=medium) ![Lobby](https://images.trvl-media.com/lodging/1000000/90000/84500/84495/021f6b45.jpg?impolicy=fcrop&w=357&h=201&p=1&q=medium) ![Room, 2 Double Beds, Non Smoking](https://images.trvl-media.com/lodging/1000000/90000/84500/84495/2dd703a6.jpg?impolicy=fcrop&w=357&h=201&p=1&q=medium) ![Seasonal outdoor pool](https://images.trvl-media.com/lodging/1000000/90000/84500/84495/b7677b1d.jpg?impolicy=fcrop&w=357&h=201&p=1&q=medium) ### La Quinta Inn & Suites by Wyndham Grand Junction [](https://www.expedia.ca/Grand-Junction-Hotels-La-Quinta-Inn-Suites-By-Wyndham-Grand-Junction.h84495.Hotel-Information) Horizon Drive District 8.8/10 Excellent (2,790 reviews) "Great hotel for price" ![United States](https://a.travel-assets.com/egds/marks/flags/us.svg) Candi CA $97 CA $111 total includes taxes & fees Jan 25 - Jan 26 [](https://www.expedia.ca/Grand-Junction-Hotels-La-Quinta-Inn-Suites-By-Wyndham-Grand-Junction.h84495.Hotel-Information) ![Terrace/patio](https://images.trvl-media.com/lodging/1000000/20000/14800/14746/19dd67dc.jpg?impolicy=fcrop&w=357&h=201&p=1&q=medium) ![Breakfast served](https://images.trvl-media.com/lodging/1000000/20000/14800/14746/a2cd6a09.jpg?impolicy=fcrop&w=357&h=201&p=1&q=medium) ![Indoor pool](https://images.trvl-media.com/lodging/1000000/20000/14800/14746/264d1ede.jpg?impolicy=fcrop&w=357&h=201&p=1&q=medium) ![Interior](https://images.trvl-media.com/lodging/1000000/20000/14800/14746/34ddcb95.jpg?impolicy=fcrop&w=357&h=201&p=1&q=medium) ### Grand Vista Hotel [](https://www.expedia.ca/Grand-Junction-Hotels-Grand-Vista-Hotel.h14746.Hotel-Information) Horizon Drive District 8.2/10 Very good (3,486 reviews) "Clean room nice bar" ![United States](https://a.travel-assets.com/egds/marks/flags/us.svg) Emerson CA $63 CA $89 total includes taxes & fees Feb 5 - Feb 6 [](https://www.expedia.ca/Grand-Junction-Hotels-Grand-Vista-Hotel.h14746.Hotel-Information) ![Lobby](https://images.trvl-media.com/lodging/1000000/480000/471200/471130/c4e6b802.jpg?impolicy=fcrop&w=357&h=201&p=1&q=medium) ![Desk, laptop workspace, iron/ironing board, free cribs/infant beds](https://images.trvl-media.com/lodging/1000000/480000/471200/471130/45525482.jpg?impolicy=fcrop&w=357&h=201&p=1&q=medium) ![Desk, laptop workspace, iron/ironing board, free cribs/infant beds](https://images.trvl-media.com/lodging/1000000/480000/471200/471130/1db83f2b.jpg?impolicy=fcrop&w=357&h=201&p=1&q=medium) ![Lobby](https://images.trvl-media.com/lodging/1000000/480000/471200/471130/f666e4b3.jpg?impolicy=fcrop&w=357&h=201&p=1&q=medium) ### Comfort Inn & Suites Fruita - Grand Junction [](https://www.expedia.ca/Grand-Junction-Hotels-Comfort-Inn-Suites.h471130.Hotel-Information) Fruita 8.4/10 Very good (1,005 reviews) "Nice clean spot to stay the night on a long drive. Employees are friendly. " ![United States](https://a.travel-assets.com/egds/marks/flags/us.svg) Rachel CA $82 CA $94 total includes taxes & fees Jan 25 - Jan 26 [](https://www.expedia.ca/Grand-Junction-Hotels-Comfort-Inn-Suites.h471130.Hotel-Information) ![Reception](https://images.trvl-media.com/lodging/1000000/20000/17200/17140/79c5aded.jpg?impolicy=fcrop&w=357&h=201&p=1&q=medium) ![Hallway](https://images.trvl-media.com/lodging/1000000/20000/17200/17140/60b42f9d.jpg?impolicy=fcrop&w=357&h=201&p=1&q=medium) ![Business centre](https://images.trvl-media.com/lodging/1000000/20000/17200/17140/b56c663d.jpg?impolicy=fcrop&w=357&h=201&p=1&q=medium) ![Lobby sitting area](https://images.trvl-media.com/lodging/1000000/20000/17200/17140/e50b7e76.jpg?impolicy=fcrop&w=357&h=201&p=1&q=medium) ### Ramada by Wyndham Grand Junction [](https://www.expedia.ca/Grand-Junction-Hotels-Ramada-By-Wyndham-Grand-Junction.h17140.Hotel-Information) Horizon Drive District 8.4/10 Very good (1,885 reviews) "Easy to find, close to dining, clean and hospitable staff." ![United States](https://a.travel-assets.com/egds/marks/flags/us.svg) Darrell CA $81 CA $93 total includes taxes & fees Jan 25 - Jan 26 [](https://www.expedia.ca/Grand-Junction-Hotels-Ramada-By-Wyndham-Grand-Junction.h17140.Hotel-Information) ![Exterior](https://images.trvl-media.com/lodging/2000000/1490000/1482600/1482507/64cec74e.jpg?impolicy=fcrop&w=357&h=201&p=1&q=medium) ![Premium bedding, pillowtop beds, desk, laptop workspace](https://images.trvl-media.com/lodging/2000000/1490000/1482600/1482507/0d2b57a7.jpg?impolicy=fcrop&w=357&h=201&p=1&q=medium) ![32-inch LCD TV with cable channels, TV](https://images.trvl-media.com/lodging/2000000/1490000/1482600/1482507/8906d24c.jpg?impolicy=fcrop&w=357&h=201&p=1&q=medium) ![Lobby](https://images.trvl-media.com/lodging/2000000/1490000/1482600/1482507/ca2efd9d.jpg?impolicy=fcrop&w=357&h=201&p=1&q=medium) ### Courtyard by Marriott Grand Junction [](https://www.expedia.ca/Grand-Junction-Hotels-Courtyard-By-Marriott-Grand-Junction.h1482507.Hotel-Information) Horizon Drive District 8.4/10 Very good (1,002 reviews) "Nice staff and ER stay when my flight was delayed overnight. The breakfast options were great too." ![United States](https://a.travel-assets.com/egds/marks/flags/us.svg) Rachel CA $124 CA $142 total includes taxes & fees Jan 28 - Jan 29 [](https://www.expedia.ca/Grand-Junction-Hotels-Courtyard-By-Marriott-Grand-Junction.h1482507.Hotel-Information) ![Lobby](https://images.trvl-media.com/lodging/1000000/30000/25200/25193/32df394c.jpg?impolicy=fcrop&w=357&h=201&p=1&q=medium) ![Room, 2 Queen Beds, Accessible, Non Smoking (Roll-In Shower)](https://images.trvl-media.com/lodging/1000000/30000/25200/25193/b6d80372.jpg?impolicy=fcrop&w=357&h=201&p=1&q=medium) ![Free daily buffet breakfast](https://images.trvl-media.com/lodging/1000000/30000/25200/25193/e2571039.jpg?impolicy=fcrop&w=357&h=201&p=1&q=medium) ![Lobby](https://images.trvl-media.com/lodging/1000000/30000/25200/25193/0fe27975.jpg?impolicy=fcrop&w=357&h=201&p=1&q=medium) ### Quality Inn Grand Junction near University [](https://www.expedia.ca/Grand-Junction-Hotels-Quality-Inn-Grand-Junction-Near-University.h25193.Hotel-Information) Horizon Drive District 8.6/10 Excellent (1,000 reviews) "Clean room. Convenient location. Friendly staff and easy check-in. Great breakfast! " ![United States](https://a.travel-assets.com/egds/marks/flags/us.svg) Elizabeth CA $76 CA $87 total includes taxes & fees Jan 30 - Jan 31 [](https://www.expedia.ca/Grand-Junction-Hotels-Quality-Inn-Grand-Junction-Near-University.h25193.Hotel-Information) ![Exterior](https://images.trvl-media.com/lodging/3000000/2650000/2647900/2647815/3f699682.jpg?impolicy=fcrop&w=357&h=201&p=1&q=medium) ![Indoor pool, sun loungers](https://images.trvl-media.com/lodging/3000000/2650000/2647900/2647815/e2b84655.jpg?impolicy=fcrop&w=357&h=201&p=1&q=medium) ![Point of interest](https://images.trvl-media.com/lodging/3000000/2650000/2647900/2647815/eec731ba.jpg?impolicy=fcrop&w=357&h=201&p=1&q=medium) ![Point of interest](https://images.trvl-media.com/lodging/3000000/2650000/2647900/2647815/8d0a2c6a.jpg?impolicy=fcrop&w=357&h=201&p=1&q=medium) ### Holiday Inn & Suites Grand Junction by IHG [](https://www.expedia.ca/Grand-Junction-Hotels-Holiday-Inn-And-Suites-Grand-Junction.h2647815.Hotel-Information) Horizon Drive District 8.6/10 Excellent (1,001 reviews) "Staff was great. " ![United States](https://a.travel-assets.com/egds/marks/flags/us.svg) Jen CA $126 CA $144 total includes taxes & fees Feb 1 - Feb 2 [](https://www.expedia.ca/Grand-Junction-Hotels-Holiday-Inn-And-Suites-Grand-Junction.h2647815.Hotel-Information) ![Indoor spa tub](https://images.trvl-media.com/lodging/1000000/20000/10400/10322/126cfec7.jpg?impolicy=fcrop&w=357&h=201&p=1&q=medium) ![Lobby sitting area](https://images.trvl-media.com/lodging/1000000/20000/10400/10322/72a1825a.jpg?impolicy=fcrop&w=357&h=201&p=1&q=medium) ![Free daily full breakfast](https://images.trvl-media.com/lodging/1000000/20000/10400/10322/a1f5f9f6.jpg?impolicy=fcrop&w=357&h=201&p=1&q=medium) ![Lobby](https://images.trvl-media.com/lodging/1000000/20000/10400/10322/033644e8.jpg?impolicy=fcrop&w=357&h=201&p=1&q=medium) ### Clarion Inn Grand Junction [](https://www.expedia.ca/Grand-Junction-Hotels-Clarion-Inn-Grand-Junction.h10322.Hotel-Information) Horizon Drive District 8.4/10 Very good (1,710 reviews) "Breakfast was good and gym , pool are in good condition. Family friendly hotel " ![United States](https://a.travel-assets.com/egds/marks/flags/us.svg) kranthikar CA $99 CA $114 total includes taxes & fees Feb 2 - Feb 3 [](https://www.expedia.ca/Grand-Junction-Hotels-Clarion-Inn-Grand-Junction.h10322.Hotel-Information) ![Restaurant](https://images.trvl-media.com/lodging/1000000/920000/915700/915633/54bd52c5.jpg?impolicy=fcrop&w=357&h=201&p=1&q=medium) ![Desk, laptop workspace, iron/ironing board, free WiFi](https://images.trvl-media.com/lodging/1000000/920000/915700/915633/3e1b7b76.jpg?impolicy=fcrop&w=357&h=201&p=1&q=medium) ![Exterior](https://images.trvl-media.com/lodging/1000000/920000/915700/915633/77f5abfe.jpg?impolicy=fcrop&w=357&h=201&p=1&q=medium) ![Exterior](https://images.trvl-media.com/lodging/1000000/920000/915700/915633/fa002c0b.jpg?impolicy=fcrop&w=357&h=201&p=1&q=medium) ### Hampton Inn Grand Junction Downtown/Historic Main Street [](https://www.expedia.ca/Grand-Junction-Hotels-Hampton-Inn-Grand-Junction-DowntownHistoric-Main-Street.h915633.Hotel-Information) Downtown 8.8/10 Excellent (1,004 reviews) "Friendly staff, clean room, great location." ![United States](https://a.travel-assets.com/egds/marks/flags/us.svg) Katherine CA $135 CA $154 total includes taxes & fees Jan 29 - Jan 30 [](https://www.expedia.ca/Grand-Junction-Hotels-Hampton-Inn-Grand-Junction-DowntownHistoric-Main-Street.h915633.Hotel-Information) Lowest nightly price found within the past 24 hours based on a 1 night stay for 2 adults. Prices and availability subject to change. Additional terms may apply. [View all properties](https://expedia.ca/Hotel-Search?startDate=2026-02-06&endDate=2026-02-07®ionId=143097&adults=2&travelerType=business_friendly&sort=RECOMMENDED&openPlayBack=true) ## Top Palisade Hotel Reviews ![Grand Vista Hotel](https://images.trvl-media.com/lodging/1000000/20000/14800/14746/7dc2f4eb_y.jpg) ### Grand Vista Hotel 10/10 Excellent "I’ve been in the hospitality business for 40 years location staff cleanliness, definitely make you feel at home .. thank you " [](https://expedia.ca/Grand-Junction-Hotels-Grand-Vista-Hotel.h14746.Hotel-Information) ![La Quinta Inn & Suites by Wyndham Grand Junction](https://images.trvl-media.com/lodging/1000000/90000/84500/84495/89cb7554_y.jpg) ### La Quinta Inn & Suites by Wyndham Grand Junction 10/10 Excellent "Very clean." [](https://expedia.ca/Grand-Junction-Hotels-La-Quinta-Inn-Suites-By-Wyndham-Grand-Junction.h84495.Hotel-Information) ![Quality Inn Grand Junction near University](https://images.trvl-media.com/lodging/1000000/30000/25200/25193/85fee6dc_y.jpg) ### Quality Inn Grand Junction near University 10/10 Excellent "great place to stay! Front desk employee is always very helpful! Gives us the same room we request each time. We stay two times a month. Breakfast is fresh and yummy. " [](https://expedia.ca/Grand-Junction-Hotels-Quality-Inn-Grand-Junction-Near-University.h25193.Hotel-Information) ![Ramada by Wyndham Grand Junction](https://images.trvl-media.com/lodging/1000000/20000/17200/17140/79c5aded_y.jpg) ### Ramada by Wyndham Grand Junction 10/10 Excellent "Easy to find, close to dining, clean and hospitable staff." [](https://expedia.ca/Grand-Junction-Hotels-Ramada-By-Wyndham-Grand-Junction.h17140.Hotel-Information) ![Clarion Inn Grand Junction](https://images.trvl-media.com/lodging/1000000/20000/10400/10322/64eb32ff_y.jpg) ### Clarion Inn Grand Junction 10/10 Excellent "Very nice place to stay" [](https://expedia.ca/Grand-Junction-Hotels-Clarion-Inn-Grand-Junction.h10322.Hotel-Information) ![Doubletree Hotel Grand Junction](https://images.trvl-media.com/lodging/1000000/10000/7900/7802/f1ef5dcf_y.jpg) ### Doubletree Hotel Grand Junction 10/10 Excellent "Room was clean staff was very nice " [](https://expedia.ca/Grand-Junction-Hotels-Doubletree-Hotel-Grand-Junction.h7802.Hotel-Information) ![Wine Country Inn Palisade](https://images.trvl-media.com/lodging/3000000/2110000/2108700/2108693/3ecd4143_y.jpg) ### Wine Country Inn Palisade 10/10 Excellent "Updated our room so that it would be easier for me to navigate since I was recovering from surgery. Staff was very helpful and pleasant, room was beautifully cleaned." [](https://expedia.ca/Grand-Junction-Hotels-Wine-Country-Inn-Palisade.h2108693.Hotel-Information) ![Comfort Inn Grand Junction I-70](https://images.trvl-media.com/lodging/1000000/10000/6100/6052/b70fb5ab_y.jpg) ### Comfort Inn Grand Junction I-70 10/10 Excellent "Customer Service was TOP NOTCH. The room was super clean, beds comfortable and it was very quiet. " [](https://expedia.ca/Grand-Junction-Hotels-Comfort-Inn-Grand-Junction-I-70.h6052.Hotel-Information) ![Courtyard by Marriott Grand Junction](https://images.trvl-media.com/lodging/2000000/1490000/1482600/1482507/270c24f4_y.jpg) ### Courtyard by Marriott Grand Junction 10/10 Excellent "Great check in experience " [](https://expedia.ca/Grand-Junction-Hotels-Courtyard-By-Marriott-Grand-Junction.h1482507.Hotel-Information) ## Frequently asked questions ### How much do business-friendly hotels in Palisade cost? ### What are the best business-friendly hotels in Palisade? ### How many business-friendly hotels are there in Palisade? ### Why book your business-friendly hotel in Palisade with Expedia? ### How can I find cheap business-friendly hotels in Palisade? ### What is there to do in Palisade near my business-friendly hotel? ## Explore a world of travel with Expedia - Lodging - Flights - Packages - Cars - Vacation Rental - More ways to book - [2 Star Hotels in East Main Street ](https://www.expedia.ca/2Star-East-Main-Street-Grand-Junction-Hotels.s20-n905402989559472128-0.Travel-Guide-Filter-Hotels) - 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