Title: Book the Best BUSINESS Hotels in Otay Ranch in 2026 | Expedia.ca

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![Yucaipa California Looking at the El Dorado Ranch Park](https://images.trvl-media.com/place/553248635976007694/d07ef212-271c-4ce4-8e9f-c38b7675f9be.jpg?impolicy=fcrop&w=1200&h=500&q=medium)

![](https://images.trvl-media.com/place/553248635976007694/d07ef212-271c-4ce4-8e9f-c38b7675f9be.jpg?impolicy=fcrop&w=1200&h=500&q=medium)

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## Check availability on Otay Ranch Business Hotels

Tonight

[Feb 6 - Feb 7](https://www.expedia.ca/Hotel-Search?regionId=553248635976007694&startDate=2026-02-06&endDate=2026-02-07&adults=2&rfrr=TG.LP.CheckPrices.Hotel&openPlayBack=true&travelerType=business_friendly)

Tomorrow

[Feb 7 - Feb 8](https://www.expedia.ca/Hotel-Search?regionId=553248635976007694&startDate=2026-02-07&endDate=2026-02-08&adults=2&rfrr=TG.LP.CheckPrices.Hotel&openPlayBack=true&travelerType=business_friendly)

This weekend

[Feb 6 - Feb 8](https://www.expedia.ca/Hotel-Search?regionId=553248635976007694&startDate=2026-02-06&endDate=2026-02-08&adults=2&rfrr=TG.LP.CheckPrices.Hotel&openPlayBack=true&travelerType=business_friendly)

Next weekend

[Feb 13 - Feb 15](https://www.expedia.ca/Hotel-Search?regionId=553248635976007694&startDate=2026-02-13&endDate=2026-02-15&adults=2&rfrr=TG.LP.CheckPrices.Hotel&openPlayBack=true&travelerType=business_friendly)

## Our top choices for Otay Ranch business-friendly hotels

![Lobby sitting area](https://images.trvl-media.com/lodging/33000000/32400000/32393800/32393708/69474629.jpg?impolicy=fcrop&w=357&h=201&p=1&q=medium)

![Lobby sitting area](https://images.trvl-media.com/lodging/33000000/32400000/32393800/32393708/ff230e8a.jpg?impolicy=fcrop&w=357&h=201&p=1&q=medium)

![Lobby lounge](https://images.trvl-media.com/lodging/33000000/32400000/32393800/32393708/3ced364d.jpg?impolicy=fcrop&w=357&h=201&p=1&q=medium)

![Lobby](https://images.trvl-media.com/lodging/33000000/32400000/32393800/32393708/83212494.jpg?impolicy=fcrop&w=357&h=201&p=1&q=medium)

### Ayres Hotel San Diego South - Chula Vista

[](https://www.expedia.ca/Chula-Vista-Hotels-Ayres-Hotel-San-Diego-South-Chula-Vista.h32393708.Hotel-Information)

Otay Ranch

9.8/10

Exceptional

(1,117 reviews)

"Cozy room, ver nice staff and in a great location to restaurants and shopping. "

![United States](https://a.travel-assets.com/egds/marks/flags/us.svg)

Amanda

[](https://www.expedia.ca/Chula-Vista-Hotels-Ayres-Hotel-San-Diego-South-Chula-Vista.h32393708.Hotel-Information)

![Lobby](https://images.trvl-media.com/lodging/20000000/19420000/19413200/19413109/507e8c4a.jpg?impolicy=fcrop&w=357&h=201&p=1&q=medium)

![In-room safe, desk, laptop workspace, iron/ironing board](https://images.trvl-media.com/lodging/20000000/19420000/19413200/19413109/ac38c6d4.jpg?impolicy=fcrop&w=357&h=201&p=1&q=medium)

![Property amenity](https://images.trvl-media.com/lodging/20000000/19420000/19413200/19413109/d573c415.jpg?impolicy=fcrop&w=357&h=201&p=1&q=medium)

![Exterior](https://images.trvl-media.com/lodging/20000000/19420000/19413200/19413109/d19ef2ff.jpg?impolicy=fcrop&w=357&h=201&p=1&q=medium)

### Residence Inn by Marriott San Diego Chula Vista

[](https://www.expedia.ca/Chula-Vista-Hotels-Residence-Inn-By-Marriott-San-Diego-Chula-Vista.h19413109.Hotel-Information)

Otay Ranch

9.4/10

Exceptional

(551 reviews)

"Beautiful large room, clean, friendly staff and great area "

![United States](https://a.travel-assets.com/egds/marks/flags/us.svg)

Frank

CA $275

CA $304 total

includes taxes & fees

Mar 8 - Mar 9

[](https://www.expedia.ca/Chula-Vista-Hotels-Residence-Inn-By-Marriott-San-Diego-Chula-Vista.h19413109.Hotel-Information)

![Standard Room, 1 King Bed, Non Smoking, Bay View](https://images.trvl-media.com/lodging/1000000/180000/170400/170338/6fe441dd.jpg?impolicy=fcrop&w=357&h=201&p=1&q=medium)

![Premium bedding, pillowtop beds, in-room safe, desk](https://images.trvl-media.com/lodging/1000000/180000/170400/170338/3eeea039.jpg?impolicy=fcrop&w=357&h=201&p=1&q=medium)

![Premium bedding, pillowtop beds, in-room safe, desk](https://images.trvl-media.com/lodging/1000000/180000/170400/170338/66a8936b.jpg?impolicy=fcrop&w=357&h=201&p=1&q=medium)

![Reception](https://images.trvl-media.com/lodging/1000000/180000/170400/170338/1e0934c7.jpg?impolicy=fcrop&w=357&h=201&p=1&q=medium)

### The DEXTRO Little Italy, BW Premier Collection

[](https://www.expedia.ca/San-Diego-Hotels-Four-Points-By-Sheraton-San-Diego-Downtown-Little-Italy.h170338.Hotel-Information)

Downtown San Diego

9.0/10

Wonderful

(1,019 reviews)

"Clean rooms and friendly staff"

![United States](https://a.travel-assets.com/egds/marks/flags/us.svg)

Topeka

CA $159

CA $184 total

includes taxes & fees

Feb 22 - Feb 23

[](https://www.expedia.ca/San-Diego-Hotels-Four-Points-By-Sheraton-San-Diego-Downtown-Little-Italy.h170338.Hotel-Information)

![Lobby sitting area](https://images.trvl-media.com/lodging/1000000/50000/41000/40962/87da6900.jpg?impolicy=fcrop&w=357&h=201&p=1&q=medium)

![Deluxe Room, Multiple Beds, Non Smoking](https://images.trvl-media.com/lodging/1000000/50000/41000/40962/363ccb07.jpg?impolicy=fcrop&w=357&h=201&p=1&q=medium)

![Exterior](https://images.trvl-media.com/lodging/1000000/50000/41000/40962/143ad063.jpg?impolicy=fcrop&w=357&h=201&p=1&q=medium)

![Lobby sitting area](https://images.trvl-media.com/lodging/1000000/50000/41000/40962/622df597.jpg?impolicy=fcrop&w=357&h=201&p=1&q=medium)

### Wyndham Garden San Diego Near SeaWorld

[](https://www.expedia.ca/San-Diego-Hotels-Wyndham-Garden-San-Diego-Near-SeaWorld.h40962.Hotel-Information)

Point Loma

7.4/10

Good

(4,165 reviews)

"Good location friendly staff"

![United States](https://a.travel-assets.com/egds/marks/flags/us.svg)

Anya

CA $129

CA $148 total

includes taxes & fees

Feb 18 - Feb 19

[](https://www.expedia.ca/San-Diego-Hotels-Wyndham-Garden-San-Diego-Near-SeaWorld.h40962.Hotel-Information)

![3 outdoor pools, cabanas (surcharge), pool umbrellas](https://images.trvl-media.com/lodging/1000000/10000/900/858/543624c5.jpg?impolicy=fcrop&w=357&h=201&p=1&q=medium)

![Exterior](https://images.trvl-media.com/lodging/1000000/10000/900/858/c5325c92.jpg?impolicy=fcrop&w=357&h=201&p=1&q=medium)

![Suite, 1 King Bed, Corner](https://images.trvl-media.com/lodging/1000000/10000/900/858/721ac3a2.jpg?impolicy=fcrop&w=357&h=201&p=1&q=medium)

![Front of property](https://images.trvl-media.com/lodging/1000000/10000/900/858/c6795882.jpg?impolicy=fcrop&w=357&h=201&p=1&q=medium)

### Hyatt Regency Mission Bay Spa and Marina

[](https://www.expedia.ca/San-Diego-Hotels-Hyatt-Regency-Mission-Bay-Spa-And-Marina.h858.Hotel-Information)

Mission Bay

8.4/10

Very good

(1,596 reviews)

"Balcony view is awesome, clean room, staff at counter and restaurant service was stunning."

![United States](https://a.travel-assets.com/egds/marks/flags/us.svg)

francisco

CA $218

CA $323 total

includes taxes & fees

Feb 8 - Feb 9

[](https://www.expedia.ca/San-Diego-Hotels-Hyatt-Regency-Mission-Bay-Spa-And-Marina.h858.Hotel-Information)

![Terrace/patio](https://images.trvl-media.com/lodging/1000000/60000/50100/50032/483e1c41.jpg?impolicy=fcrop&w=357&h=201&p=1&q=medium)

![Property grounds](https://images.trvl-media.com/lodging/1000000/60000/50100/50032/8aabd9fc.jpg?impolicy=fcrop&w=357&h=201&p=1&q=medium)

![Front of property - evening/night](https://images.trvl-media.com/lodging/1000000/60000/50100/50032/089f0b78.jpg?impolicy=fcrop&w=357&h=201&p=1&q=medium)

![Lobby](https://images.trvl-media.com/lodging/1000000/60000/50100/50032/2b0cb40b.jpg?impolicy=fcrop&w=357&h=201&p=1&q=medium)

### Ayres Lodge Alpine

[](https://www.expedia.ca/Alpine-Hotels-Ayres-Lodge-Alpine.h50032.Hotel-Information)

Alpine

9.2/10

Wonderful

(1,004 reviews)

"Perfect location "

![United States](https://a.travel-assets.com/egds/marks/flags/us.svg)

Raul,jr

CA $315

CA $341 total

includes taxes & fees

Feb 14 - Feb 15

[](https://www.expedia.ca/Alpine-Hotels-Ayres-Lodge-Alpine.h50032.Hotel-Information)

![3 outdoor pools, cabanas (surcharge), pool umbrellas](https://images.trvl-media.com/lodging/34000000/33670000/33661500/33661441/22ecf276.jpg?impolicy=fcrop&w=357&h=201&p=1&q=medium)

![7 restaurants, breakfast served](https://images.trvl-media.com/lodging/34000000/33670000/33661500/33661441/250333ae.jpg?impolicy=fcrop&w=357&h=201&p=1&q=medium)

![Exterior](https://images.trvl-media.com/lodging/34000000/33670000/33661500/33661441/3bb415c6.jpg?impolicy=fcrop&w=357&h=201&p=1&q=medium)

![7 restaurants, breakfast served](https://images.trvl-media.com/lodging/34000000/33670000/33661500/33661441/700997bd.jpg?impolicy=fcrop&w=357&h=201&p=1&q=medium)

### Sycuan Casino Resort

[](https://www.expedia.ca/El-Cajon-Hotels-Sycuan-Casino-Resort.h33661441.Hotel-Information)

El Cajon

9.2/10

Wonderful

(1,709 reviews)

"Very clean resort. "

![United States](https://a.travel-assets.com/egds/marks/flags/us.svg)

Petrina

CA $135

CA $165 total

includes taxes & fees

Feb 9 - Feb 10

[](https://www.expedia.ca/El-Cajon-Hotels-Sycuan-Casino-Resort.h33661441.Hotel-Information)

![Restaurant](https://images.trvl-media.com/lodging/3000000/2920000/2918200/2918129/45e02c21.jpg?impolicy=fcrop&w=357&h=201&p=1&q=medium)

![Lobby](https://images.trvl-media.com/lodging/3000000/2920000/2918200/2918129/f3168007.jpg?impolicy=fcrop&w=357&h=201&p=1&q=medium)

![Bar (on property)](https://images.trvl-media.com/lodging/3000000/2920000/2918200/2918129/49bcb235.jpg?impolicy=fcrop&w=357&h=201&p=1&q=medium)

![Exterior](https://images.trvl-media.com/lodging/3000000/2920000/2918200/2918129/a0a6825c.jpg?impolicy=fcrop&w=357&h=201&p=1&q=medium)

### Residence Inn by Marriott San Diego Downtown/Gaslamp Quarter

[](https://www.expedia.ca/San-Diego-Hotels-Residence-Inn-By-Marriott-San-Diego-DowntownGaslamp-Quarter.h2918129.Hotel-Information)

Downtown San Diego

9.0/10

Wonderful

(1,268 reviews)

"Friendly staff, great location, excellent value overall "

![United States](https://a.travel-assets.com/egds/marks/flags/us.svg)

Maryann

CA $177

CA $205 total

includes taxes & fees

Feb 15 - Feb 16

[](https://www.expedia.ca/San-Diego-Hotels-Residence-Inn-By-Marriott-San-Diego-DowntownGaslamp-Quarter.h2918129.Hotel-Information)

![Property amenity](https://images.trvl-media.com/lodging/1000000/580000/571600/571545/48aa6044.jpg?impolicy=fcrop&w=357&h=201&p=1&q=medium)

![Bar (on property)](https://images.trvl-media.com/lodging/1000000/580000/571600/571545/b4dcb6f0.jpg?impolicy=fcrop&w=357&h=201&p=1&q=medium)

![Exterior](https://images.trvl-media.com/lodging/1000000/580000/571600/571545/e79ecd34.jpg?impolicy=fcrop&w=357&h=201&p=1&q=medium)

![Outdoor pool](https://images.trvl-media.com/lodging/1000000/580000/571600/571545/63c64f0a.jpg?impolicy=fcrop&w=357&h=201&p=1&q=medium)

### Crowne Plaza San Diego - Mission Valley by IHG

[](https://www.expedia.ca/San-Diego-Hotels-Crowne-Plaza-San-Diego-Mission-Valley.h571545.Hotel-Information)

Mission Valley

8.0/10

Very good

(1,014 reviews)

"Great stay"

![United States](https://a.travel-assets.com/egds/marks/flags/us.svg)

Viviann

CA $138

CA $160 total

includes taxes & fees

Mar 1 - Mar 2

[](https://www.expedia.ca/San-Diego-Hotels-Crowne-Plaza-San-Diego-Mission-Valley.h571545.Hotel-Information)

![Terrace/patio](https://images.trvl-media.com/lodging/1000000/10000/2600/2514/4003f7ef.jpg?impolicy=fcrop&w=357&h=201&p=1&q=medium)

![Outdoor pool, open 7:00 AM to 10:00 PM, pool umbrellas, sun loungers](https://images.trvl-media.com/lodging/1000000/10000/2600/2514/77d3b0aa.jpg?impolicy=fcrop&w=357&h=201&p=1&q=medium)

![Sports facility](https://images.trvl-media.com/lodging/1000000/10000/2600/2514/b0a789a8.jpg?impolicy=fcrop&w=357&h=201&p=1&q=medium)

![View from room](https://images.trvl-media.com/lodging/1000000/10000/2600/2514/a24a0e44.jpg?impolicy=fcrop&w=357&h=201&p=1&q=medium)

### Bay Club Hotel & Marina

[](https://www.expedia.ca/San-Diego-Hotels-Bay-Club-Hotel-Marina.h2514.Hotel-Information)

Point Loma

9.2/10

Wonderful

(3,361 reviews)

"We had great time and enjoyed our stay "

![United States](https://a.travel-assets.com/egds/marks/flags/us.svg)

sadra

CA $176

CA $202 total

includes taxes & fees

Feb 24 - Feb 25

[](https://www.expedia.ca/San-Diego-Hotels-Bay-Club-Hotel-Marina.h2514.Hotel-Information)

Lowest nightly price found within the past 24 hours based on a 1 night stay for 2 adults. Prices and availability subject to change. Additional terms may apply.

[View all properties](https://expedia.ca/Hotel-Search?startDate=2026-02-20&endDate=2026-02-21&regionId=553248635976007694&adults=2&travelerType=business_friendly&sort=RECOMMENDED&openPlayBack=true)

## Top Otay Ranch Hotel Reviews

![Hard Rock Hotel San Diego](https://images.trvl-media.com/lodging/2000000/1740000/1731600/1731557/fbbdfc57_y.jpg)

### Hard Rock Hotel San Diego

10/10 Excellent

"Room was very clean and luxurious "

[](https://expedia.ca/San-Diego-Hotels-Hard-Rock-Hotel-San-Diego.h1731557.Hotel-Information)

![Wyndham San Diego Bayside](https://images.trvl-media.com/lodging/1000000/20000/11200/11177/c44ff51d_y.jpg)

### Wyndham San Diego Bayside

10/10 Excellent

"Love the view to the bay. Room was clean and location had a lot of great restaurant options "

[](https://expedia.ca/San-Diego-Hotels-Wyndham-San-Diego-Bayside.h11177.Hotel-Information)

![The Dana on Mission Bay](https://images.trvl-media.com/lodging/1000000/50000/41000/40953/08585098_y.jpg)

### The Dana on Mission Bay

10/10 Excellent

"Fast Room Service "

[](https://expedia.ca/San-Diego-Hotels-The-Dana-On-Mission-Bay.h40953.Hotel-Information)

![Bahia Resort Hotel](https://images.trvl-media.com/lodging/1000000/20000/18300/18241/86eea647_y.jpg)

### Bahia Resort Hotel

10/10 Excellent

"All the staff goes out of their way, the resort is in the middle of everything. No need to drive out. So many delicious restaurants in and close. The rooms were perfect. We enjoyed every minute there "

[](https://expedia.ca/San-Diego-Hotels-Bahia-Resort-Hotel.h18241.Hotel-Information)

![Paradise Point Resort & Spa](https://images.trvl-media.com/lodging/1000000/10000/3800/3731/bc1e5add_y.jpg)

### Paradise Point Resort & Spa

10/10 Excellent

"Beautiful place, clean room excellent staff. The pools are so lovely!"

[](https://expedia.ca/San-Diego-Hotels-Paradise-Point-Resort-Spa.h3731.Hotel-Information)

![The Sofia Hotel](https://images.trvl-media.com/lodging/2000000/1580000/1573900/1573807/ba6cea84_y.jpg)

### The Sofia Hotel

10/10 Excellent

"Rooms were clean, the beds were soo comfy, and staff was nice. "

[](https://expedia.ca/San-Diego-Hotels-The-Sofia-Hotel.h1573807.Hotel-Information)

![Courtyard by Marriott San Diego Downtown Little Italy](https://images.trvl-media.com/lodging/1000000/20000/13300/13205/db3040ff_y.jpg)

### Courtyard by Marriott San Diego Downtown Little Italy

10/10 Excellent

"Staff was polite, rooms were clean, atmosphere was great being close to little Italy, easy access to restaurants and stores and close to the Bay Area"

[](https://expedia.ca/San-Diego-Hotels-The-Little-Italy-Hotel-In-Downtown-San-Diego.h13205.Hotel-Information)

![Best Western Seven Seas](https://images.trvl-media.com/lodging/1000000/10000/1800/1734/w3837h2556x3y3-8b148daf_y.jpg)

### Best Western Seven Seas

10/10 Excellent

"The Best Western than seven seas is special to me because I stayed there as a child with my parents and grandparents. It is old motor in style San Diego or best Western in its old form.. The staff is great and it has a nice pool and Jacuzzi.. It is very affordable.. "

[](https://expedia.ca/San-Diego-Hotels-Best-Western-Seven-Seas.h1734.Hotel-Information)

![The DEXTRO Little Italy, BW Premier Collection](https://images.trvl-media.com/lodging/1000000/180000/170400/170338/6fe441dd_y.jpg)

### The DEXTRO Little Italy, BW Premier Collection

10/10 Excellent

"This place was really nice and cozy. Friendly staff. The only thing I didn’t like was we had to pay $35 per car for parking. "

[](https://expedia.ca/San-Diego-Hotels-Four-Points-By-Sheraton-San-Diego-Downtown-Little-Italy.h170338.Hotel-Information)

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