Title: 10 Best Hotels in Otay Mesa West, San Diego for 2026 | Expedia.ca [Vacation Rentals in San Diego](https://expedia.ca/San-Diego-Vacation-Rentals.d3073.Travel-Guide-VacationRentals)[Flights to San Diego](https://expedia.ca/Cheap-Flights-To-San-Diego.d3073.Travel-Guide-Flights)[Things to do in San Diego](https://expedia.ca/Things-To-Do-In-San-Diego.d3073.Travel-Guide-Activities)[Otay Mesa West Car Rentals](https://expedia.ca/Car-Rentals-In-Otay-Mesa-West.d553248625809641010.Car-Rental-Guide)[Otay Mesa West Vacations](https://expedia.ca/Otay-Mesa-West.d553248625809641010.Destination-Travel-Guides) ![Default HTG hotel image](https://a.travel-assets.com/travel-assets-manager/fallback-images-brand/bex_lodging_v2.jpg?impolicy=fcrop&w=1200&h=500&q=medium) # Hotels in Otay Mesa West, San Diego - ![](https://a.travel-assets.com/travel-assets-manager/pictogram-bex/light__calendar_shield.svg) ### Change your mind Book hotels with free cancellation - ![](https://a.travel-assets.com/travel-assets-manager/pictogram-bex/light__deals.svg) ### Treat yourself Sign in to save 10% or more on thousands of hotels [Sign in](https://www.expedia.ca/login) - ![](https://a.travel-assets.com/travel-assets-manager/pictogram-bex/light__bed.svg) ### Be picky Search almost a million properties worldwide ## Check prices for these dates Tonight [Dec 21 - Dec 22](https://www.expedia.ca/Hotel-Search?regionId=553248625809641010&startDate=2025-12-21&endDate=2025-12-22&adults=2&rfrr=TG.LP.CheckPrices.Hotel&openPlayBack=true) Tomorrow [Dec 22 - Dec 23](https://www.expedia.ca/Hotel-Search?regionId=553248625809641010&startDate=2025-12-22&endDate=2025-12-23&adults=2&rfrr=TG.LP.CheckPrices.Hotel&openPlayBack=true) Next weekend [Dec 26 - Dec 28](https://www.expedia.ca/Hotel-Search?regionId=553248625809641010&startDate=2025-12-26&endDate=2025-12-28&adults=2&rfrr=TG.LP.CheckPrices.Hotel&openPlayBack=true) In two weeks [Jan 2 - Jan 4](https://www.expedia.ca/Hotel-Search?regionId=553248625809641010&startDate=2026-01-02&endDate=2026-01-04&adults=2&rfrr=TG.LP.CheckPrices.Hotel&openPlayBack=true) Recommended Price (low to high) Distance Star rating ## Our top choices for Otay Mesa West hotels ![Property entrance](https://images.trvl-media.com/lodging/1000000/30000/23900/23816/243b93bc.jpg?impolicy=fcrop&w=357&h=201&p=1&q=medium) ![Lobby sitting area](https://images.trvl-media.com/lodging/1000000/30000/23900/23816/7f37543f.jpg?impolicy=fcrop&w=357&h=201&p=1&q=medium) ![Room, 2 Double Beds (Fab)](https://images.trvl-media.com/lodging/1000000/30000/23900/23816/febc9a76.jpg?impolicy=fcrop&w=357&h=201&p=1&q=medium) ![Lobby sitting area](https://images.trvl-media.com/lodging/1000000/30000/23900/23816/8f3ed06e.jpg?impolicy=fcrop&w=357&h=201&p=1&q=medium) ### The Bristol Hotel San Diego [](https://www.expedia.ca/San-Diego-Hotels-The-Bristol-Hotel-San-Diego.h23816.Hotel-Information) 18.5 km from Otay Mesa West 8.6/10 Excellent (1464) "I loved my stay here" ![United States](https://a.travel-assets.com/egds/marks/flags/us.svg) José CA $175 CA $203 total includes taxes & fees Dec 23 - Dec 24 [](https://www.expedia.ca/San-Diego-Hotels-The-Bristol-Hotel-San-Diego.h23816.Hotel-Information) ![2 outdoor pools, open 6 AM to 10:00 PM, cabanas (surcharge)](https://images.trvl-media.com/lodging/1000000/30000/24400/24394/9078a9ee.jpg?impolicy=fcrop&w=357&h=201&p=1&q=medium) ![Exterior](https://images.trvl-media.com/lodging/1000000/30000/24400/24394/80be4d0f.jpg?impolicy=fcrop&w=357&h=201&p=1&q=medium) ![2 bars/lounges, poolside bar](https://images.trvl-media.com/lodging/1000000/30000/24400/24394/eb8b9673.jpg?impolicy=fcrop&w=357&h=201&p=1&q=medium) ![View from property](https://images.trvl-media.com/lodging/1000000/30000/24400/24394/5488e3f5.jpg?impolicy=fcrop&w=357&h=201&p=1&q=medium) ### Marriott Marquis San Diego Marina [](https://www.expedia.ca/San-Diego-Hotels-Marriott-Marquis-San-Diego-Marina.h24394.Hotel-Information) Marina District, 17.9 km from Otay Mesa West 9.2/10 Wonderful (1955) "Amazing hotel Superb view Friendly staff Clean and neat rooms " ![United States](https://a.travel-assets.com/egds/marks/flags/us.svg) Chirag CA $233 CA $343 total includes taxes & fees Dec 23 - Dec 24 [](https://www.expedia.ca/San-Diego-Hotels-Marriott-Marquis-San-Diego-Marina.h24394.Hotel-Information) ![Deluxe Room, 2 Queen Beds](https://images.trvl-media.com/lodging/1000000/20000/12100/12073/b34080ca.jpg?impolicy=fcrop&w=357&h=201&p=1&q=medium) ![Exterior](https://images.trvl-media.com/lodging/1000000/20000/12100/12073/3c106350.jpg?impolicy=fcrop&w=357&h=201&p=1&q=medium) ![Exterior](https://images.trvl-media.com/lodging/1000000/20000/12100/12073/e448a271.jpg?impolicy=fcrop&w=357&h=201&p=1&q=medium) ![Hypo-allergenic bedding, in-room safe, desk, iron/ironing board](https://images.trvl-media.com/lodging/1000000/20000/12100/12073/d33c10c2.jpg?impolicy=fcrop&w=357&h=201&p=1&q=medium) ### Manchester Grand Hyatt San Diego [](https://www.expedia.ca/San-Diego-Hotels-Manchester-Grand-Hyatt-San-Diego.h12073.Hotel-Information) Marina District, 18.2 km from Otay Mesa West 9.0/10 Wonderful (2881) "Lovely hotel with friendly staff." ![United States](https://a.travel-assets.com/egds/marks/flags/us.svg) Lynnea CA $208 CA $317 total includes taxes & fees Dec 23 - Dec 24 [](https://www.expedia.ca/San-Diego-Hotels-Manchester-Grand-Hyatt-San-Diego.h12073.Hotel-Information) ![Lobby](https://images.trvl-media.com/lodging/1000000/10000/5400/5328/cfe599b5.jpg?impolicy=fcrop&w=357&h=201&p=1&q=medium) ![Luxury Suite, 1 King Bed | Living area](https://images.trvl-media.com/lodging/1000000/10000/5400/5328/d22de167.jpg?impolicy=fcrop&w=357&h=201&p=1&q=medium) ![Lobby](https://images.trvl-media.com/lodging/1000000/10000/5400/5328/451480f5.jpg?impolicy=fcrop&w=357&h=201&p=1&q=medium) ![Lunch and dinner served, American cuisine](https://images.trvl-media.com/lodging/1000000/10000/5400/5328/85a135ae.jpg?impolicy=fcrop&w=357&h=201&p=1&q=medium) ### Embassy Suites by Hilton San Diego Bay Downtown [](https://www.expedia.ca/San-Diego-Hotels-Embassy-Suites-By-Hilton-San-Diego-Bay-Downtown.h5328.Hotel-Information) Marina District, 18.4 km from Otay Mesa West 9.0/10 Wonderful (1555) "Very nice, and clean hotel. Friendly staff, and close to amenities. " ![United States](https://a.travel-assets.com/egds/marks/flags/us.svg) Araceli CA $237 CA $324 total includes taxes & fees Dec 28 - Dec 29 [](https://www.expedia.ca/San-Diego-Hotels-Embassy-Suites-By-Hilton-San-Diego-Bay-Downtown.h5328.Hotel-Information) ![Meeting facility](https://images.trvl-media.com/lodging/1000000/30000/27600/27516/1b87fc03.jpg?impolicy=fcrop&w=357&h=201&p=1&q=medium) ![Premium bedding, pillowtop beds, in-room safe, desk](https://images.trvl-media.com/lodging/1000000/30000/27600/27516/ca66f35a.jpg?impolicy=fcrop&w=357&h=201&p=1&q=medium) ![Beach nearby, white sand](https://images.trvl-media.com/lodging/1000000/30000/27600/27516/31f9c777.jpg?impolicy=fcrop&w=357&h=201&p=1&q=medium) ![Hospitality Suite, 1 King Bed, Bay View | Living room](https://images.trvl-media.com/lodging/1000000/30000/27600/27516/d02824a2.jpg?impolicy=fcrop&w=357&h=201&p=1&q=medium) ### The Westin San Diego Bayview [](https://www.expedia.ca/San-Diego-Hotels-The-Westin-San-Diego-Downtown.h27516.Hotel-Information) 18.7 km from Otay Mesa West 8.6/10 Excellent (1076) "I loved the hotel rooms bar area jacuzzi area everything was great it was in a pretty location will definitely come back " ![United States](https://a.travel-assets.com/egds/marks/flags/us.svg) Alliyah CA $187 CA $256 total includes taxes & fees Dec 29 - Dec 30 [](https://www.expedia.ca/San-Diego-Hotels-The-Westin-San-Diego-Downtown.h27516.Hotel-Information) ![Outdoor pool, sun loungers](https://images.trvl-media.com/lodging/2000000/1880000/1871700/1871645/9fc82331.jpg?impolicy=fcrop&w=357&h=201&p=1&q=medium) ![2 bars/lounges, lobby lounge](https://images.trvl-media.com/lodging/2000000/1880000/1871700/1871645/ed2e1ba0.jpg?impolicy=fcrop&w=357&h=201&p=1&q=medium) ![Breakfast, lunch, dinner served; Californian cuisine, ocean views ](https://images.trvl-media.com/lodging/2000000/1880000/1871700/1871645/06f19e3f.jpg?impolicy=fcrop&w=357&h=201&p=1&q=medium) ![Exterior](https://images.trvl-media.com/lodging/2000000/1880000/1871700/1871645/f10fc62f.jpg?impolicy=fcrop&w=357&h=201&p=1&q=medium) ### Hilton San Diego Bayfront [](https://www.expedia.ca/San-Diego-Hotels-Hilton-San-Diego-Bayfront.h1871645.Hotel-Information) Marina District, 17.2 km from Otay Mesa West 8.6/10 Excellent (1885) "Enjoyed my stay" ![United States](https://a.travel-assets.com/egds/marks/flags/us.svg) Brandon CA $170 CA $265 total includes taxes & fees Jan 4 - Jan 5, 2026 [](https://www.expedia.ca/San-Diego-Hotels-Hilton-San-Diego-Bayfront.h1871645.Hotel-Information) ![Standard Room, 1 King Bed, Non Smoking, Bay View](https://images.trvl-media.com/lodging/1000000/180000/170400/170338/6fe441dd.jpg?impolicy=fcrop&w=357&h=201&p=1&q=medium) ![Premium bedding, pillowtop beds, in-room safe, desk](https://images.trvl-media.com/lodging/1000000/180000/170400/170338/66a8936b.jpg?impolicy=fcrop&w=357&h=201&p=1&q=medium) ![Premium bedding, pillowtop beds, in-room safe, desk](https://images.trvl-media.com/lodging/1000000/180000/170400/170338/3eeea039.jpg?impolicy=fcrop&w=357&h=201&p=1&q=medium) ![Outdoor pool, pool umbrellas, sun loungers](https://images.trvl-media.com/lodging/1000000/180000/170400/170338/1a09735e.jpg?impolicy=fcrop&w=357&h=201&p=1&q=medium) ### The DEXTRO Little Italy, BW Premier Collection [](https://www.expedia.ca/San-Diego-Hotels-Four-Points-By-Sheraton-San-Diego-Downtown-Little-Italy.h170338.Hotel-Information) 19.1 km from Otay Mesa West 8.8/10 Excellent (773) "would stay again and recommend " ![United States](https://a.travel-assets.com/egds/marks/flags/us.svg) Brendi CA $151 CA $175 total includes taxes & fees Dec 23 - Dec 24 [](https://www.expedia.ca/San-Diego-Hotels-Four-Points-By-Sheraton-San-Diego-Downtown-Little-Italy.h170338.Hotel-Information) ![Property grounds](https://images.trvl-media.com/lodging/1000000/10000/3800/3731/bc1e5add.jpg?impolicy=fcrop&w=357&h=201&p=1&q=medium) ![2 restaurants, breakfast, lunch, dinner served; Californian cuisine](https://images.trvl-media.com/lodging/1000000/10000/3800/3731/7c71b256.jpg?impolicy=fcrop&w=357&h=201&p=1&q=medium) ![2 restaurants, breakfast, lunch, dinner served; Californian cuisine](https://images.trvl-media.com/lodging/1000000/10000/3800/3731/7fe47de0.jpg?impolicy=fcrop&w=357&h=201&p=1&q=medium) ![5 outdoor pools, a heated pool, pool umbrellas, sun loungers](https://images.trvl-media.com/lodging/1000000/10000/3800/3731/d0f041ab.jpg?impolicy=fcrop&w=357&h=201&p=1&q=medium) ### Paradise Point Resort & Spa [](https://www.expedia.ca/San-Diego-Hotels-Paradise-Point-Resort-Spa.h3731.Hotel-Information) Mission Bay, 27.9 km from Otay Mesa West 8.8/10 Excellent (2355) "Great stay, top tier service and excellent customer care " ![Canada](https://a.travel-assets.com/egds/marks/flags/ca.svg) Meriem CA $179 CA $278 total includes taxes & fees Jan 11 - Jan 12, 2026 [](https://www.expedia.ca/San-Diego-Hotels-Paradise-Point-Resort-Spa.h3731.Hotel-Information) ![Premium bedding, pillowtop beds, desk, laptop workspace](https://images.trvl-media.com/lodging/12000000/11490000/11486100/11486063/c31e05e6.jpg?impolicy=fcrop&w=357&h=201&p=1&q=medium) ![Hallway](https://images.trvl-media.com/lodging/12000000/11490000/11486100/11486063/ec632047.jpg?impolicy=fcrop&w=357&h=201&p=1&q=medium) ![Front of property - evening/night](https://images.trvl-media.com/lodging/12000000/11490000/11486100/11486063/53d75480.jpg?impolicy=fcrop&w=357&h=201&p=1&q=medium) ![Reception](https://images.trvl-media.com/lodging/12000000/11490000/11486100/11486063/1fbe17de.jpg?impolicy=fcrop&w=357&h=201&p=1&q=medium) ### Staypineapple, Hotel Z, Gaslamp San Diego [](https://www.expedia.ca/San-Diego-Hotels-Staypineapple.h11486063.Hotel-Information) Gaslamp Quarter, 17.8 km from Otay Mesa West 9.4/10 Exceptional (1004) "Great location " ![United States](https://a.travel-assets.com/egds/marks/flags/us.svg) Mohammad CA $122 CA $182 total includes taxes & fees Jan 5 - Jan 6, 2026 [](https://www.expedia.ca/San-Diego-Hotels-Staypineapple.h11486063.Hotel-Information) ![Suite, 2 Queen Beds, Non Smoking, Refrigerator (with Sofabed)](https://images.trvl-media.com/lodging/3000000/2820000/2816700/2816688/f3777dfe.jpg?impolicy=fcrop&w=357&h=201&p=1&q=medium) ![Outdoor pool, open 9:00 AM to 10:00 PM, pool umbrellas, sun loungers](https://images.trvl-media.com/lodging/3000000/2820000/2816700/2816688/ade03197.jpg?impolicy=fcrop&w=357&h=201&p=1&q=medium) ![Exterior](https://images.trvl-media.com/lodging/3000000/2820000/2816700/2816688/a5cb77af.jpg?impolicy=fcrop&w=357&h=201&p=1&q=medium) ![Bar (on property)](https://images.trvl-media.com/lodging/3000000/2820000/2816700/2816688/91baa1e7.jpg?impolicy=fcrop&w=357&h=201&p=1&q=medium) ### Best Western Plus Marina Gateway Hotel [](https://www.expedia.ca/National-City-Hotels-Best-Western-Plus-Marina-Gateway-Hotel.h2816688.Hotel-Information) 10.5 km from Otay Mesa West 9.2/10 Wonderful (3560) "Room was clean, staff was friendly and helpful." ![United States](https://a.travel-assets.com/egds/marks/flags/us.svg) Maria CA $144 CA $159 total includes taxes & fees Jan 7 - Jan 8, 2026 [](https://www.expedia.ca/National-City-Hotels-Best-Western-Plus-Marina-Gateway-Hotel.h2816688.Hotel-Information) ![Garden](https://images.trvl-media.com/lodging/42000000/41510000/41504800/41504735/0bbd67f4.jpg?impolicy=fcrop&w=357&h=201&p=1&q=medium) ![Premium bedding, in-room safe, desk, laptop workspace](https://images.trvl-media.com/lodging/42000000/41510000/41504800/41504735/7442075b.jpg?impolicy=fcrop&w=357&h=201&p=1&q=medium) ![Lobby](https://images.trvl-media.com/lodging/42000000/41510000/41504800/41504735/43ef19cb.jpg?impolicy=fcrop&w=357&h=201&p=1&q=medium) ![Front of property](https://images.trvl-media.com/lodging/42000000/41510000/41504800/41504735/8077fd39.jpg?impolicy=fcrop&w=357&h=201&p=1&q=medium) ### Legacy Resort Hotel & Spa [](https://www.expedia.ca/San-Diego-Hotels-Legacy-Resort-Hotel-Spa.h41504735.Hotel-Information) 22.9 km from Otay Mesa West 9.2/10 Wonderful (2946) "Everything was super comfortable and the room was surprisingly affordable for the amenities you get. We will definitely stay there again if we go to San Diego." ![United States](https://a.travel-assets.com/egds/marks/flags/us.svg) Eric CA $210 CA $241 total includes taxes & fees Dec 23 - Dec 24 [](https://www.expedia.ca/San-Diego-Hotels-Legacy-Resort-Hotel-Spa.h41504735.Hotel-Information) ![Outdoor pool, a heated pool](https://images.trvl-media.com/lodging/1000000/20000/15600/15555/e83f0930.jpg?impolicy=fcrop&w=357&h=201&p=1&q=medium) ![Cafe](https://images.trvl-media.com/lodging/1000000/20000/15600/15555/13a8c861.jpg?impolicy=fcrop&w=357&h=201&p=1&q=medium) ![View from property](https://images.trvl-media.com/lodging/1000000/20000/15600/15555/3f3cb725.jpg?impolicy=fcrop&w=357&h=201&p=1&q=medium) ![Premium Suite, 1 King Bed, Lanai, Pool View | Lanai](https://images.trvl-media.com/lodging/1000000/20000/15600/15555/c671c203.jpg?impolicy=fcrop&w=357&h=201&p=1&q=medium) ### The Wayfarer San Diego [](https://www.expedia.ca/San-Diego-Hotels-The-Wayfarer-San-Diego.h15555.Hotel-Information) Mission Beach, 30.2 km from Otay Mesa West 9.4/10 Exceptional (1716) "Great room, clean and updated property, exceptional service, perfect location. Loved our stay and can't wait to return. " ![United States](https://a.travel-assets.com/egds/marks/flags/us.svg) Michelle CA $247 CA $284 total includes taxes & fees Dec 23 - Dec 24 [](https://www.expedia.ca/San-Diego-Hotels-The-Wayfarer-San-Diego.h15555.Hotel-Information) ![Suite, 1 King Bed with Sofa bed, City View | View from room](https://images.trvl-media.com/lodging/1000000/20000/17900/17865/a25502e5.jpg?impolicy=fcrop&w=357&h=201&p=1&q=medium) ![Reception](https://images.trvl-media.com/lodging/1000000/20000/17900/17865/46c12abc.jpg?impolicy=fcrop&w=357&h=201&p=1&q=medium) ![Exterior](https://images.trvl-media.com/lodging/1000000/20000/17900/17865/f34abdc9.jpg?impolicy=fcrop&w=357&h=201&p=1&q=medium) ![Lounge](https://images.trvl-media.com/lodging/1000000/20000/17900/17865/97d1106b.jpg?impolicy=fcrop&w=357&h=201&p=1&q=medium) ### Marriott Vacation Club®, San Diego [](https://www.expedia.ca/San-Diego-Hotels-Marriott-Vacation-Club-Pulse.h17865.Hotel-Information) 18.4 km from Otay Mesa West 9.4/10 Exceptional (1009) "Room was spacious! Best hotel I’ve ever been to! " ![United States](https://a.travel-assets.com/egds/marks/flags/us.svg) Liyah CA $186 CA $216 total includes taxes & fees Jan 4 - Jan 5, 2026 [](https://www.expedia.ca/San-Diego-Hotels-Marriott-Vacation-Club-Pulse.h17865.Hotel-Information) ![2 outdoor pools, a heated pool, sun loungers](https://images.trvl-media.com/lodging/1000000/50000/41000/40953/08585098.jpg?impolicy=fcrop&w=357&h=201&p=1&q=medium) ![In-room safe, desk, laptop workspace, iron/ironing board](https://images.trvl-media.com/lodging/1000000/50000/41000/40953/2c4c818b.jpg?impolicy=fcrop&w=357&h=201&p=1&q=medium) ![Aerial view](https://images.trvl-media.com/lodging/1000000/50000/41000/40953/01ecd568.jpg?impolicy=fcrop&w=357&h=201&p=1&q=medium) ![Daily cooked-to-order breakfast for a fee](https://images.trvl-media.com/lodging/1000000/50000/41000/40953/f03b817a.jpg?impolicy=fcrop&w=357&h=201&p=1&q=medium) ### The Dana on Mission Bay [](https://www.expedia.ca/San-Diego-Hotels-The-Dana-On-Mission-Bay.h40953.Hotel-Information) Mission Bay, 27.1 km from Otay Mesa West 9.0/10 Wonderful (3936) "Always love staying here. Staff was very courteous and the rooms very clean. " ![United States](https://a.travel-assets.com/egds/marks/flags/us.svg) Eric CA $192 CA $248 total includes taxes & fees Dec 23 - Dec 24 [](https://www.expedia.ca/San-Diego-Hotels-The-Dana-On-Mission-Bay.h40953.Hotel-Information) ![View from room](https://images.trvl-media.com/lodging/1000000/30000/24700/24669/5294b74f.jpg?impolicy=fcrop&w=357&h=201&p=1&q=medium) ![Lobby](https://images.trvl-media.com/lodging/1000000/30000/24700/24669/1ebcc57c.jpg?impolicy=fcrop&w=357&h=201&p=1&q=medium) ![Front of property](https://images.trvl-media.com/lodging/1000000/30000/24700/24669/f150c7c4.jpg?impolicy=fcrop&w=357&h=201&p=1&q=medium) ![Breakfast, lunch, dinner served; American cuisine, beach views ](https://images.trvl-media.com/lodging/1000000/30000/24700/24669/dd54db0c.jpg?impolicy=fcrop&w=357&h=201&p=1&q=medium) ### Catamaran Resort and Spa [](https://www.expedia.ca/San-Diego-Hotels-Catamaran-Resort-And-Spa.h24669.Hotel-Information) Mission Beach, 30.1 km from Otay Mesa West 8.6/10 Excellent (1112) "Great place to vacation. " ![United States](https://a.travel-assets.com/egds/marks/flags/us.svg) Manuel CA $210 CA $315 total includes taxes & fees Dec 29 - Dec 30 [](https://www.expedia.ca/San-Diego-Hotels-Catamaran-Resort-And-Spa.h24669.Hotel-Information) ![Outdoor pool, open 7:00 AM to 10:00 PM, cabanas (surcharge)](https://images.trvl-media.com/lodging/1000000/30000/25600/25598/bbcdbd6d.jpg?impolicy=fcrop&w=357&h=201&p=1&q=medium) ![Premium bedding, down comforters, pillowtop beds, in-room safe](https://images.trvl-media.com/lodging/1000000/30000/25600/25598/c2cecb91.jpg?impolicy=fcrop&w=357&h=201&p=1&q=medium) ![On the beach, white sand, windsurfing, beach volleyball](https://images.trvl-media.com/lodging/1000000/30000/25600/25598/c20f7d47.jpg?impolicy=fcrop&w=357&h=201&p=1&q=medium) ![2 restaurants, breakfast, lunch, dinner served; American cuisine](https://images.trvl-media.com/lodging/1000000/30000/25600/25598/de48676b.jpg?impolicy=fcrop&w=357&h=201&p=1&q=medium) ### San Diego Mission Bay Resort [](https://www.expedia.ca/San-Diego-Hotels-San-Diego-Mission-Bay-Resort.h25598.Hotel-Information) Mission Bay, 26.7 km from Otay Mesa West 8.4/10 Very good (1311) "Room was super clean and updated, location up against the bay was perfect. We really enjoyed our stay and want to come back soon!" ![United States](https://a.travel-assets.com/egds/marks/flags/us.svg) Haley CA $203 CA $296 total includes taxes & fees Jan 1 - Jan 2, 2026 [](https://www.expedia.ca/San-Diego-Hotels-San-Diego-Mission-Bay-Resort.h25598.Hotel-Information) ![Terrace/patio](https://images.trvl-media.com/lodging/1000000/20000/11200/11177/c44ff51d.jpg?impolicy=fcrop&w=357&h=201&p=1&q=medium) ![Exterior](https://images.trvl-media.com/lodging/1000000/20000/11200/11177/5142b853.jpg?impolicy=fcrop&w=357&h=201&p=1&q=medium) ![Lobby](https://images.trvl-media.com/lodging/1000000/20000/11200/11177/7f3bc7ed.jpg?impolicy=fcrop&w=357&h=201&p=1&q=medium) ![City view](https://images.trvl-media.com/lodging/1000000/20000/11200/11177/88f9cd22.jpg?impolicy=fcrop&w=357&h=201&p=1&q=medium) ### Wyndham San Diego Bayside [](https://www.expedia.ca/San-Diego-Hotels-Wyndham-San-Diego-Bayside.h11177.Hotel-Information) 19.2 km from Otay Mesa West 8.4/10 Very good (6044) "Always an amazing stay" ![United States](https://a.travel-assets.com/egds/marks/flags/us.svg) Jana CA $187 CA $256 total includes taxes & fees Dec 24 - Dec 25 [](https://www.expedia.ca/San-Diego-Hotels-Wyndham-San-Diego-Bayside.h11177.Hotel-Information) ![Exterior](https://images.trvl-media.com/lodging/1000000/10000/2600/2514/8c022c3d.jpg?impolicy=fcrop&w=357&h=201&p=1&q=medium) ![View from room](https://images.trvl-media.com/lodging/1000000/10000/2600/2514/676f55ca.jpg?impolicy=fcrop&w=357&h=201&p=1&q=medium) ![Breakfast, lunch, dinner served; American cuisine, pool views ](https://images.trvl-media.com/lodging/1000000/10000/2600/2514/1f20ac82.jpg?impolicy=fcrop&w=357&h=201&p=1&q=medium) ![Outdoor pool, open 7:00 AM to 10:00 PM, pool umbrellas, sun loungers](https://images.trvl-media.com/lodging/1000000/10000/2600/2514/5619e933.jpg?impolicy=fcrop&w=357&h=201&p=1&q=medium) ### Bay Club Hotel & Marina [](https://www.expedia.ca/San-Diego-Hotels-Bay-Club-Hotel-Marina.h2514.Hotel-Information) 22.1 km from Otay Mesa West 9.2/10 Wonderful (3208) "Great stay and location!" ![United States](https://a.travel-assets.com/egds/marks/flags/us.svg) Jason CA $160 CA $184 total includes taxes & fees Jan 4 - Jan 5, 2026 [](https://www.expedia.ca/San-Diego-Hotels-Bay-Club-Hotel-Marina.h2514.Hotel-Information) ![City view from property](https://images.trvl-media.com/lodging/1000000/20000/13300/13205/db3040ff.jpg?impolicy=fcrop&w=357&h=201&p=1&q=medium) ![View from room](https://images.trvl-media.com/lodging/1000000/20000/13300/13205/0339a25b.jpg?impolicy=fcrop&w=357&h=201&p=1&q=medium) ![Suite, 1 Bedroom | Living room](https://images.trvl-media.com/lodging/1000000/20000/13300/13205/7182df27.jpg?impolicy=fcrop&w=357&h=201&p=1&q=medium) ![Lobby lounge](https://images.trvl-media.com/lodging/1000000/20000/13300/13205/c69001c7.jpg?impolicy=fcrop&w=357&h=201&p=1&q=medium) ### Courtyard by Marriott San Diego Downtown Little Italy [](https://www.expedia.ca/San-Diego-Hotels-The-Little-Italy-Hotel-In-Downtown-San-Diego.h13205.Hotel-Information) Little Italy, 19.2 km from Otay Mesa West 9.0/10 Wonderful (125) "It was a nice place to stay at" ![United States](https://a.travel-assets.com/egds/marks/flags/us.svg) Eric CA $181 CA $209 total includes taxes & fees Dec 30 - Dec 31 [](https://www.expedia.ca/San-Diego-Hotels-The-Little-Italy-Hotel-In-Downtown-San-Diego.h13205.Hotel-Information) ![Reception](https://images.trvl-media.com/lodging/1000000/10000/9700/9660/8496a8ba.jpg?impolicy=fcrop&w=357&h=201&p=1&q=medium) ![Hypo-allergenic bedding, in-room safe, iron/ironing board](https://images.trvl-media.com/lodging/1000000/10000/9700/9660/5c2bbbc6.jpg?impolicy=fcrop&w=357&h=201&p=1&q=medium) ![Hypo-allergenic bedding, in-room safe, iron/ironing board](https://images.trvl-media.com/lodging/1000000/10000/9700/9660/3af899ba.jpg?impolicy=fcrop&w=357&h=201&p=1&q=medium) ![Breakfast, lunch, dinner served; Californian cuisine, pool views ](https://images.trvl-media.com/lodging/1000000/10000/9700/9660/8c14c190.jpg?impolicy=fcrop&w=357&h=201&p=1&q=medium) ### Best Western Plus Island Palms Hotel & Marina [](https://www.expedia.ca/San-Diego-Hotels-Best-Western-Plus-Island-Palms-Hotel-Marina.h9660.Hotel-Information) 22.1 km from Otay Mesa West 8.8/10 Excellent (1559) "Staff was great, easy check in and great location" ![United States](https://a.travel-assets.com/egds/marks/flags/us.svg) Alysa CA $153 CA $176 total includes taxes & fees Jan 5 - Jan 6, 2026 [](https://www.expedia.ca/San-Diego-Hotels-Best-Western-Plus-Island-Palms-Hotel-Marina.h9660.Hotel-Information) Lowest nightly price found within the past 24 hours based on a 1 night stay for 2 adults. Prices and availability subject to change. Additional terms may apply. [View all properties](https://expedia.ca/Hotel-Search?startDate=2026-01-05&endDate=2026-01-06®ionId=553248625809641010&adults=2&sort=RECOMMENDED&openPlayBack=true) ## Where to stay in Otay Mesa West Find the best Otay Mesa West areas and neighborhoods for the activities you enjoy most. - Downtown San Diego - Gaslamp Quarter - Pacific Beach - Mission Beach - Ocean Beach ![](https://a.travel-assets.com/findyours-php/viewfinder/images/res70/481000/481093-Downtown-San-Diego.jpg?impolicy=fcrop&w=960&h=540&p=1&q=medium) ![](https://a.travel-assets.com/findyours-php/viewfinder/images/res70/480000/480742-Maritime-Museum-Of-San-Diego.jpg?impolicy=fcrop&w=960&h=540&p=1&q=medium) ![](https://a.travel-assets.com/findyours-php/viewfinder/images/res70/476000/476416-Downtown-San-Diego.jpg?impolicy=fcrop&w=960&h=540&p=1&q=medium) ![](https://a.travel-assets.com/findyours-php/viewfinder/images/res70/480000/480743-Maritime-Museum-Of-San-Diego.jpg?impolicy=fcrop&w=960&h=540&p=1&q=medium) ![](https://a.travel-assets.com/findyours-php/viewfinder/images/res70/476000/476415-Downtown-San-Diego.jpg?impolicy=fcrop&w=960&h=540&p=1&q=medium) [](https://www.expedia.ca/Hotel-Search?pwaOverlay=map®ionId=800123) ![Downtown San Diego map](https://maps.googleapis.com/maps/api/staticmap?&size=289x340&map_id=c017d89749dc74ad&markers=icon:%7C&path=enc:yfwfEzeejUaMaj%40fa%40k%5CbLaPx%40qOkGcWu%40i%5B%60DgKrIcFdRgF%7CrAsAHjJvK%60IqKjOFzR%7EP%7CI%7BH%7CO%7CIfNma%40hn%40%7B%40fIe%5ChZma%40t%40o%40kSei%40E_FfEiEnLwEd%40&key=AIzaSyAoVHdVOa5-BDRxGhFoAHYIHPst1T09Jo0&signature=Cs9sAV_TcaQK48f0iT1-t86hPRE=) ### Downtown San Diego Cultural and financial hub, Downtown San Diego boasts the Symphony, Opera, theaters, museums, and historic sites like Gaslamp Quarter. Enjoy diverse shops, dining, nightlife, and convenient public transport options. [See properties](https://www.expedia.ca/Hotel-Search?regionId=800123) ![Gaslamp Quarter showing street scenes, night scenes and a city](https://a.travel-assets.com/findyours-php/viewfinder/images/res70/22000/22037-San-Diego-Gaslamp-Quarter.jpg?impolicy=fcrop&w=960&h=540&p=1&q=medium) ![](https://a.travel-assets.com/findyours-php/viewfinder/images/res70/475000/475881-San-Diego-Gaslamp-Quarter.jpg?impolicy=fcrop&w=960&h=540&p=1&q=medium) ![](https://a.travel-assets.com/findyours-php/viewfinder/images/res70/480000/480435-San-Diego-Gaslamp-Quarter.jpg?impolicy=fcrop&w=960&h=540&p=1&q=medium) ![](https://a.travel-assets.com/findyours-php/viewfinder/images/res70/480000/480422-San-Diego-Gaslamp-Quarter.jpg?impolicy=fcrop&w=960&h=540&p=1&q=medium) ![](https://a.travel-assets.com/findyours-php/viewfinder/images/res70/480000/480432-San-Diego-Gaslamp-Quarter.jpg?impolicy=fcrop&w=960&h=540&p=1&q=medium) [](https://www.expedia.ca/Hotel-Search?pwaOverlay=map®ionId=6130021) ![Gaslamp Quarter map](https://maps.googleapis.com/maps/api/staticmap?&size=289x340&map_id=c017d89749dc74ad&markers=icon:%7C&path=enc:mmtfEh%7CbjUAwJqIDCm%5B%60x%40OmEpJ%7DPD%40zAiE%40A_B%7BEBFj%5B_HH&key=AIzaSyAoVHdVOa5-BDRxGhFoAHYIHPst1T09Jo0&signature=68cMX7ldk9-J6tcepLMBQKKwvpY=) ### Gaslamp Quarter Downtown San Diego's historic district boasts Victorian-era buildings, now housing vibrant restaurants, shops, and entertainment venues. Stroll from Broadway to Harbor Drive, and 4th to 6th Avenue, admiring the newly installed gaslamps at Market Street. [See properties](https://www.expedia.ca/Hotel-Search?regionId=6130021) ![Pacific Beach Park showing a sandy beach](https://a.travel-assets.com/findyours-php/viewfinder/images/res70/152000/152283-Pacific-Beach.jpg?impolicy=fcrop&w=960&h=540&p=1&q=medium) ![Pacific Beach Park which includes rugged coastline, a coastal town and surfing](https://a.travel-assets.com/findyours-php/viewfinder/images/res70/152000/152049-San-Diego.jpg?impolicy=fcrop&w=960&h=540&p=1&q=medium) ![Pacific Beach Park featuring a sandy beach and a sunset](https://a.travel-assets.com/findyours-php/viewfinder/images/res70/152000/152293-Pacific-Beach.jpg?impolicy=fcrop&w=960&h=540&p=1&q=medium) ![Pacific Beach Park featuring a beach](https://a.travel-assets.com/findyours-php/viewfinder/images/res70/152000/152300-Pacific-Beach.jpg?impolicy=fcrop&w=960&h=540&p=1&q=medium) ![Pacific Beach Park which includes a beach bar and drinks or beverages](https://a.travel-assets.com/findyours-php/viewfinder/images/res70/152000/152301-Pacific-Beach.jpg?impolicy=fcrop&w=960&h=540&p=1&q=medium) [](https://www.expedia.ca/Hotel-Search?pwaOverlay=map®ionId=6185751) ![Pacific Beach map](https://maps.googleapis.com/maps/api/staticmap?&size=289x340&map_id=c017d89749dc74ad&markers=icon:%7C&path=enc:agfgEvyujUgHcNcG%60IiBwN%7BKtBkf%40inCoKyIyEoFcHy%40aKoT%60mBq_B%7Cl%40aZb%40xB%7DAlAuMdQsExHkAvMbB%7CVpV_F%7CGrk%40tPgDhDlTbMbDlZu%40%60V%7EDxQfMtAlJg%40xH_GxEkRnGkUrA%7DP%60IiFbTv%40lR%60J%7CNcKjBzCfUec%40%60L%7BUxIkP%60IuM%7CH&key=AIzaSyAoVHdVOa5-BDRxGhFoAHYIHPst1T09Jo0&signature=5FbBeekgWkepp0jnCE7WEy_Qh88=) ### Pacific Beach Boasting a lively nightlife scene, Pacific Beach offers miles of sandy shores, a bustling 3.2-mile boardwalk, and attractions like Crystal Pier and Kate Sessions Park. Enjoy local shops, bars, and eateries along the vibrant walkway. [See properties](https://www.expedia.ca/Hotel-Search?regionId=6185751) ![Belmont Park which includes a garden and rides](https://a.travel-assets.com/findyours-php/viewfinder/images/res70/22000/22160-Belmont-Park.jpg?impolicy=fcrop&w=960&h=540&p=1&q=medium) ![Belmont Park featuring street scenes and rides as well as a large group of people](https://a.travel-assets.com/findyours-php/viewfinder/images/res70/22000/22159-Belmont-Park.jpg?impolicy=fcrop&w=960&h=540&p=1&q=medium) ![Belmont Park which includes a city, rides and street scenes](https://a.travel-assets.com/findyours-php/viewfinder/images/res70/22000/22161-Belmont-Park.jpg?impolicy=fcrop&w=960&h=540&p=1&q=medium) ![](https://a.travel-assets.com/findyours-php/viewfinder/images/res70/187000/187064-Belmont-Park.jpg?impolicy=fcrop&w=960&h=540&p=1&q=medium) Photo by Belmont Park ![Belmont Park](https://a.travel-assets.com/findyours-php/viewfinder/images/res70/187000/187072-Belmont-Park.jpg?impolicy=fcrop&w=960&h=540&p=1&q=medium) Photo by Belmont Park [](https://www.expedia.ca/Hotel-Search?pwaOverlay=map®ionId=553248635998112279) ![Mission Beach map](https://maps.googleapis.com/maps/api/staticmap?&size=289x340&map_id=c017d89749dc74ad&markers=icon:%7C&path=enc:ec%7DfE%7CgujU_Die%40%7BAYqk%40sBclAvBeNh%40wNtAcg%40%60H_DqUxGwAlD%7EF%60Dm%40v%40%40Bb%40tDIhRqFnGs%40nEBzOdBzF%40xI%7DAvNwH%60BMfBZt%40m%40EhIzJy%40hNJI%7DIrBvAjErA%7EJb%40%7CMcEjJsFzArBfF%7EcA&key=AIzaSyAoVHdVOa5-BDRxGhFoAHYIHPst1T09Jo0&signature=hFrZWtAC8u-2IGYk_Bcs7ztzP5Q=) ### Mission Beach Spanning nearly two miles of oceanfront, this sandbar community offers sunbathing, surfing, and beach volleyball, with nearby attractions like Belmont Park's Giant Dipper Roller Coaster and SeaWorld in Mission Bay Park. [See properties](https://www.expedia.ca/Hotel-Search?regionId=553248635998112279) ![](https://a.travel-assets.com/findyours-php/viewfinder/images/res70/481000/481019-Ocean-Beach-Nei.jpg?impolicy=fcrop&w=960&h=540&p=1&q=medium) ![](https://a.travel-assets.com/findyours-php/viewfinder/images/res70/480000/480252-San-Diego-City.jpg?impolicy=fcrop&w=960&h=540&p=1&q=medium) ![](https://a.travel-assets.com/findyours-php/viewfinder/images/res70/481000/481012-Ocean-Beach-Nei.jpg?impolicy=fcrop&w=960&h=540&p=1&q=medium) ![](https://a.travel-assets.com/findyours-php/viewfinder/images/res70/481000/481011-Ocean-Beach-Nei.jpg?impolicy=fcrop&w=960&h=540&p=1&q=medium) ![](https://a.travel-assets.com/findyours-php/viewfinder/images/res70/481000/481016-Ocean-Beach-Nei.jpg?impolicy=fcrop&w=960&h=540&p=1&q=medium) [](https://www.expedia.ca/Hotel-Search?pwaOverlay=map®ionId=177689) ![Ocean Beach map](https://maps.googleapis.com/maps/api/staticmap?&size=289x340&map_id=c017d89749dc74ad&markers=icon:%7C&path=enc:eq%7CfEneujUqO%7ByCl%5CdMdL%7B%40pnB%60%60BoUlb%40crB%60I&key=AIzaSyAoVHdVOa5-BDRxGhFoAHYIHPst1T09Jo0&signature=lCc_uj9JIfh1kP738Xl1bJJqo_A=) ### Ocean Beach Ocean Beach is known for its stunning beaches, and with sights like Dog Beach and Sunset Cliffs Natural Park, you won't get bored spending a day wandering around this part of San Diego. [See properties](https://www.expedia.ca/Hotel-Search?regionId=177689) ## Top Otay Mesa West Hotel Reviews ![Courtyard by Marriott San Diego Downtown Little Italy](https://images.trvl-media.com/lodging/1000000/20000/13300/13205/db3040ff_y.jpg) ### Courtyard by Marriott San Diego Downtown Little Italy 10/10 Excellent "Clean room and friendly staff. Great views for the city. " [](https://expedia.ca/San-Diego-Hotels-The-Little-Italy-Hotel-In-Downtown-San-Diego.h13205.Hotel-Information) ![Hampton Inn San Diego/Mission Valley](https://images.trvl-media.com/lodging/1000000/10000/4500/4415/036e1947_y.jpg) ### Hampton Inn San Diego/Mission Valley 10/10 Excellent "Room spotless staff very pleasant. Breakfast good vaule " [](https://expedia.ca/San-Diego-Hotels-Hampton-Inn-San-Diego-Mission-Valley.h4415.Hotel-Information) ![Legacy Resort Hotel & Spa](https://images.trvl-media.com/lodging/42000000/41510000/41504800/41504735/0bbd67f4_y.jpg) ### Legacy Resort Hotel & Spa 10/10 Excellent "El está bien, cómodo, limpio y se mira bastante nuevo, si tuviera que decir algo mal, lo único sería el internet, el que es free no sirve absolutamente para nada prácticamente obligándote a comprar su paquete de internet que la verdad tampoco es que sea muy bueno, pienso que deberían mejorar eso al menos ya que uno está pagando debería ser por algo bueno. En todo lo demás está bastante bien y muy céntrico y cerca de todo. " [](https://expedia.ca/San-Diego-Hotels-Legacy-Resort-Hotel-Spa.h41504735.Hotel-Information) ![Kings Inn San Diego](https://images.trvl-media.com/lodging/1000000/20000/17000/16910/a5f26080_y.jpg) ### Kings Inn San Diego 10/10 Excellent "Room was clean. It’s clearly an older facility that was beeen renovated. Loved the Christmas theme and energy. Breakfast not included, which is stated. There is a restaurant, the Waffle Spot or Stop, that was good with reasonable prices. " [](https://expedia.ca/San-Diego-Hotels-Kings-Inn-San-Diego-Seaworld-Zoo.h16910.Hotel-Information) ![Lafayette Hotel & Club](https://images.trvl-media.com/lodging/39000000/38080000/38077800/38077738/91a184a3_y.jpg) ### Lafayette Hotel & Club 10/10 Excellent "Very clean and tidy, super beautiful." [](https://expedia.ca/San-Diego-Hotels-Lafayette-Hotel.h38077738.Hotel-Information) ![Bay Club Hotel & Marina](https://images.trvl-media.com/lodging/1000000/10000/2600/2514/8c022c3d_y.jpg) ### Bay Club Hotel & Marina 10/10 Excellent "Excellent" [](https://expedia.ca/San-Diego-Hotels-Bay-Club-Hotel-Marina.h2514.Hotel-Information) ![Hampton Inn & Suites by Hilton San Diego SeaWorld](https://images.trvl-media.com/lodging/13000000/12970000/12963400/12963301/cc52443d_y.jpg) ### Hampton Inn & Suites by Hilton San Diego SeaWorld 10/10 Excellent "really big rooms and delicious breakfast! would come back again" [](https://expedia.ca/San-Diego-Hotels-Hampton-Inn-Suites-San-Diego-Point-Loma.h12963301.Hotel-Information) ![The Sofia Hotel](https://images.trvl-media.com/lodging/2000000/1580000/1573900/1573807/ba6cea84_y.jpg) ### The Sofia Hotel 10/10 Excellent "The recently remodled room was extremely luxurious. I loved the large tv that extended out and to the bed. It was great for late night movie watching. Friendly and accommodating staff. " [](https://expedia.ca/San-Diego-Hotels-The-Sofia-Hotel.h1573807.Hotel-Information) ![Hotel del Coronado, Curio Collection by Hilton](https://images.trvl-media.com/lodging/1000000/10000/7500/7496/20fe4d95_y.jpg) ### Hotel del Coronado, Curio Collection by Hilton 10/10 Excellent "Wonderful restoration of the lobby and updating the rooms" [](https://expedia.ca/Coronado-Hotels-Hotel-Del-Coronado.h7496.Hotel-Information) ## Frequently asked questions ### What are the best family hotels in Otay Mesa West? > Another family-friendly option is the [Motel 6 San Diego, CA - Southbay](https://www.expedia.ca/San-Diego-Hotels-Motel-6-San-Diego.h663151.Hotel-Information). This hotel is particularly accommodating for families with children, offering connecting rooms, which allow for easy supervision and bonding time. Young travellers can enjoy free stays, adding great value for families on a budget. Like the Best Western, this property also features housekeeping services and microwaves, making it convenient for families to settle in and feel at home. ### What hotels in Otay Mesa West offer free breakfast? ### What are the best budget hotels in Otay Mesa West? > This hotel also caters to families, providing free cribs and accessible parking, making it easy for parents traveling with young children. The fitness centre allows adults to stay active, while free WiFi keeps everyone connected. With a customer review rating of 7.8, it's clear that many have found it to be a reliable choice for quality and convenience. ### Can I cancel my hotel reservation on Expedia? ### How can I save on a Otay Mesa West hotel booking with Expedia? ### How much is the nightly rate at a Otay Mesa West hotel? ## Explore a world of travel with Expedia - Lodging - Flights - Packages - Cars - Other - More ways to book - [Hotels near Beyer Blvd Trolley Station ](https://www.expedia.ca/Beyer-Blvd-Trolley-Station-Hotels.d6186828.Travel-Guide-Hotels) - [Bonita Hotels ](https://www.expedia.ca/Bonita-Hotels.d177687.Travel-Guide-Hotels) - [Hotels near Brown Field Municipal ](https://www.expedia.ca/Brown-Field-Municipal-Airport-Hotels.0-aSDM-0.Travel-Guide-Filter-Hotels) - [Hotels near Chula Vista Center ](https://www.expedia.ca/Chula-Vista-Center-Hotels.0-l553248621560505608-0.Travel-Guide-Filter-Hotels) - [Chula Vista Hotels ](https://www.expedia.ca/Chula-Vista-Hotels.d7442.Travel-Guide-Hotels) - [Coronado Cays Hotels ](https://www.expedia.ca/Coronado-Cays-Coronado-Hotels.0-n553248635976471145-0.Travel-Guide-Filter-Hotels) - [Hotels near H St Trolley Station ](https://www.expedia.ca/H-St-Trolley-Station-Hotels.d6186820.Travel-Guide-Hotels) - [Hotels near Imperial Beach ](https://www.expedia.ca/Imperial-Beach-Hotels.0-l553248635976496923-0.Travel-Guide-Filter-Hotels) - [Imperial Beach Hotels ](https://www.expedia.ca/Imperial-Beach-Hotels.d177683.Travel-Guide-Hotels) - [Hotels near Iris Avenue Trolley Station ](https://www.expedia.ca/Iris-Avenue-Trolley-Station-Hotels.d6186826.Travel-Guide-Hotels) - [Hotels near Kaiser Permanente Otay Mesa Medical Offices ](https://www.expedia.ca/Kaiser-Permanente-Otay-Mesa-Medical-Offices-Hotels.0-l553248634333595416-0.Travel-Guide-Filter-Hotels) - [Hotels near Las Americas Premium Outlets ](https://www.expedia.ca/Las-Americas-Premium-Outlets-Hotels.0-l6150696-0.Travel-Guide-Filter-Hotels) - [Nestor Hotels ](https://www.expedia.ca/Nestor-San-Diego-Hotels.0-n553248635976476281-0.Travel-Guide-Filter-Hotels) - [Hotels near North Island Credit Union Amphitheatre ](https://www.expedia.ca/North-Island-Credit-Union-Amphitheatre-Hotels.0-l6128061-0.Travel-Guide-Filter-Hotels) - [All Inclusive Resorts and in Ocean View Hills ](https://www.expedia.ca/Ocean-View-Hills-San-Diego-Hotels-All-Inclusive-Hotel.0-n553248635976008220-0-tAllInclusiveHotel.Travel-Guide-Filter-Hotels) - [Beach Hotel Hotels in Ocean View Hills ](https://www.expedia.ca/Ocean-View-Hills-San-Diego-Hotels-Beach-Hotel.0-n553248635976008220-0-tBeachHotel.Travel-Guide-Filter-Hotels) - [Hotels with Hot Tubs in Ocean View Hills ](https://www.expedia.ca/Ocean-View-Hills-San-Diego-Hotels-Hotels-With-Hot-Tubs.0-n553248635976008220-0-tHotelsWithHotTubs.Travel-Guide-Filter-Hotels) - [Mountain Hotels in Ocean View Hills ](https://www.expedia.ca/Ocean-View-Hills-San-Diego-Hotels-Mountain-Hotels.0-n553248635976008220-0-tMountainHotels.Travel-Guide-Filter-Hotels) - [Oceanfront Hotels in Ocean View Hills ](https://www.expedia.ca/Ocean-View-Hills-San-Diego-Hotels-Oceanfront-Hotels.0-n553248635976008220-0-tOceanfrontHotels.Travel-Guide-Filter-Hotels) - [Hotel Wedding Venues Hotels in Ocean View Hills ](https://www.expedia.ca/Ocean-View-Hills-San-Diego-Hotels-Wedding-Hotels.0-n553248635976008220-0-tWeddingHotels.Travel-Guide-Filter-Hotels) - [Ocean View Hills Hotels ](https://www.expedia.ca/Ocean-View-Hills-San-Diego-Hotels.0-n553248635976008220-0.Travel-Guide-Filter-Hotels) - [Business Hotels in Otay ](https://www.expedia.ca/Otay-Chula-Vista-Hotels-Business-Hotel.0-n177685-0-tBusinessHotel.Travel-Guide-Filter-Hotels) - [Oceanfront Hotels in Otay ](https://www.expedia.ca/Otay-Chula-Vista-Hotels-Oceanfront-Hotels.0-n177685-0-tOceanfrontHotels.Travel-Guide-Filter-Hotels) - [Pet-Friendly Hotels in Otay ](https://www.expedia.ca/Otay-Chula-Vista-Hotels-Pet-Friendly-Hotel.0-n177685-0-tPetfriendlyHotel.Travel-Guide-Filter-Hotels) - [Otay Hotels ](https://www.expedia.ca/Otay-Chula-Vista-Hotels.0-n177685-0.Travel-Guide-Filter-Hotels) - [Otay Mesa Hotels ](https://www.expedia.ca/Otay-Mesa-San-Diego-Hotels.0-n6263723-0.Travel-Guide-Filter-Hotels) - [Otay Ranch Village 1 Hotels ](https://www.expedia.ca/Otay-Ranch-Village-1-Chula-Vista-Hotels.0-n553248635976473906-0.Travel-Guide-Filter-Hotels) - [Otay Ranch Village West Hotels ](https://www.expedia.ca/Otay-Ranch-Village-West-Chula-Vista-Hotels.0-n553248635976473051-0.Travel-Guide-Filter-Hotels) - [Condo Rentals in Palm Ave Trolley Station ](https://www.expedia.ca/Palm-Ave-Trolley-Station-Condos.d6186824-aaCondos.Travel-Guide-Accommodation) - [Villas in Palm Ave Trolley Station ](https://www.expedia.ca/Palm-Ave-Trolley-Station-Villas.d6186824-aaVillas.Travel-Guide-Accommodation) - [Rancho del Rey Hotels ](https://www.expedia.ca/Rancho-Del-Rey-Chula-Vista-Hotels.0-n553248635976480627-0.Travel-Guide-Filter-Hotels) - [Rancho - Del Rey II Hotels ](https://www.expedia.ca/Rancho-Del-Rey-II-Chula-Vista-Hotels.0-n553248635976470133-0.Travel-Guide-Filter-Hotels) - [San Diego Hotels ](https://www.expedia.ca/San-Diego-Hotels.d3073.Travel-Guide-Hotels) - [Farmstay in San Ysidro ](https://www.expedia.ca/San-Ysidro-Agritourism.d8380-aaAgritourism.Travel-Guide-Accommodation) - [Hotels near San Ysidro Border Crossing ](https://www.expedia.ca/San-Ysidro-Border-Crossing-Hotels.0-l553248621551385128-0.Travel-Guide-Filter-Hotels) - [Chalets in San Ysidro ](https://www.expedia.ca/San-Ysidro-Chalets.d8380-aaChalets.Travel-Guide-Accommodation) - [Guest Houses in San Ysidro ](https://www.expedia.ca/San-Ysidro-Guest-Houses.d8380-aaGuestHouses.Travel-Guide-Accommodation) - [Boutique Hotels in San Ysidro ](https://www.expedia.ca/San-Ysidro-Hotels-Boutique-Hotel.0-0-d8380-tBoutiqueHotel.Travel-Guide-Filter-Hotels) - [Business Hotels in San Ysidro ](https://www.expedia.ca/San-Ysidro-Hotels-Business-Hotel.0-0-d8380-tBusinessHotel.Travel-Guide-Filter-Hotels) - [Cheap Hotels in San Ysidro ](https://www.expedia.ca/San-Ysidro-Hotels-Cheap-Hotels.0-0-d8380-tCheapHotels.Travel-Guide-Filter-Hotels) - [Hotels & Resorts for Couples in San Ysidro ](https://www.expedia.ca/San-Ysidro-Hotels-Couples-Resorts-Hotels.0-0-d8380-tCouplesResortsHotels.Travel-Guide-Filter-Hotels) - [Hotels with Early Check-in in San Ysidro ](https://www.expedia.ca/San-Ysidro-Hotels-Hotel-With-Early-Check-In.0-0-d8380-thotelwithearlycheckin.Travel-Guide-Filter-Hotels) - [Hotels with Free Airport Shuttle in San Ysidro ](https://www.expedia.ca/San-Ysidro-Hotels-Hotels-With-Free-Airport-Shuttle.0-0-d8380-tHotelswithFreeAirportShuttle.Travel-Guide-Filter-Hotels) - [Luxury Hotels in San Ysidro ](https://www.expedia.ca/San-Ysidro-Hotels-Luxury-Hotel.0-0-d8380-tLuxuryHotel.Travel-Guide-Filter-Hotels) - [Pet-Friendly Hotels in San Ysidro ](https://www.expedia.ca/San-Ysidro-Hotels-Pet-Friendly-Hotel.0-0-d8380-tPetfriendlyHotel.Travel-Guide-Filter-Hotels) - [Winery Hotels in San Ysidro ](https://www.expedia.ca/San-Ysidro-Hotels-Winery-Hotel.0-0-d8380-tWineryHotel.Travel-Guide-Filter-Hotels) - [San Ysidro Hotels ](https://www.expedia.ca/San-Ysidro-Hotels.d8380.Travel-Guide-Hotels) - [Inns in San Ysidro ](https://www.expedia.ca/San-Ysidro-Inns.d8380-aaInns.Travel-Guide-Accommodation) - [Motels in San Ysidro ](https://www.expedia.ca/San-Ysidro-Motels.d8380-aaMotels.Travel-Guide-Accommodation) - [Resorts in San Ysidro ](https://www.expedia.ca/San-Ysidro-Resort-Hotels.d8380-aaResortHotels.Travel-Guide-Accommodation) - [Hotels near San Ysidro Transit Center Station ](https://www.expedia.ca/San-Ysidro-Transit-Center-Station-Hotels.d6186831.Travel-Guide-Hotels) - [Hotels near Sesame Place San Diego ](https://www.expedia.ca/Sesame-Place-San-Diego-Hotels.0-l6266353-0.Travel-Guide-Filter-Hotels) - [Hotels near Sharp Chula Vista Medical Center ](https://www.expedia.ca/Sharp-Chula-Vista-Medical-Center-Hotels.0-l553248621560505607-0.Travel-Guide-Filter-Hotels) - [Hotels near Silver Strand State Beach ](https://www.expedia.ca/Silver-Strand-State-Beach-Hotels.0-l6171344-0.Travel-Guide-Filter-Hotels) - [South Bay Hotels ](https://www.expedia.ca/South-Bay-Hotels.d6056572.Travel-Guide-Hotels) - [Guest Houses in South San Diego ](https://www.expedia.ca/South-San-Diego-Guest-Houses.d553248632063518562-aaGuestHouses.Travel-Guide-Accommodation) - [Beach Hotel Hotels in South San Diego ](https://www.expedia.ca/South-San-Diego-Hotels-Beach-Hotel.0-0-d553248632063518562-tBeachHotel.Travel-Guide-Filter-Hotels) - [Boutique Hotels in South San Diego ](https://www.expedia.ca/South-San-Diego-Hotels-Boutique-Hotel.0-0-d553248632063518562-tBoutiqueHotel.Travel-Guide-Filter-Hotels) - [Cheap Hotels in South San Diego ](https://www.expedia.ca/South-San-Diego-Hotels-Cheap-Hotels.0-0-d553248632063518562-tCheapHotels.Travel-Guide-Filter-Hotels) - [Hotels & Resorts for Couples in South San Diego ](https://www.expedia.ca/South-San-Diego-Hotels-Couples-Resorts-Hotels.0-0-d553248632063518562-tCouplesResortsHotels.Travel-Guide-Filter-Hotels) - [Family Hotels in South San Diego ](https://www.expedia.ca/South-San-Diego-Hotels-Family-Hotel.0-0-d553248632063518562-tFamilyHotel.Travel-Guide-Filter-Hotels) - [Hotels with a Pool in South San Diego ](https://www.expedia.ca/South-San-Diego-Hotels-Hotel-With-Pool.0-0-d553248632063518562-tHotelwithPool.Travel-Guide-Filter-Hotels) - [Hotels with Bar in South San Diego ](https://www.expedia.ca/South-San-Diego-Hotels-Hotels-With-Bar.0-0-d553248632063518562-tHotelswithBar.Travel-Guide-Filter-Hotels) - [Hotels with Free Breakfast in South San Diego ](https://www.expedia.ca/South-San-Diego-Hotels-Hotels-With-Free-Breakfast.0-0-d553248632063518562-tHotelswithFreeBreakfast.Travel-Guide-Filter-Hotels) - [Hotels with Hot Tubs in South San Diego ](https://www.expedia.ca/South-San-Diego-Hotels-Hotels-With-Hot-Tubs.0-0-d553248632063518562-tHotelsWithHotTubs.Travel-Guide-Filter-Hotels) - [Hotels with Kitchenettes in South San Diego ](https://www.expedia.ca/South-San-Diego-Hotels-Hotels-With-Kitchenettes.0-0-d553248632063518562-tHotelswithKitchenettes.Travel-Guide-Filter-Hotels) - [Oakwood Hotels in South San Diego ](https://www.expedia.ca/South-San-Diego-Hotels-Oakwood.0-0-d553248632063518562--bOakwood.Travel-Guide-Filter-Hotels) - [Oceanfront Hotels in South San Diego ](https://www.expedia.ca/South-San-Diego-Hotels-Oceanfront-Hotels.0-0-d553248632063518562-tOceanfrontHotels.Travel-Guide-Filter-Hotels) - [Spa Hotels in South San Diego ](https://www.expedia.ca/South-San-Diego-Hotels-Spa-Hotel.0-0-d553248632063518562-tSpaHotel.Travel-Guide-Filter-Hotels) - [Waterpark Hotels in South San Diego ](https://www.expedia.ca/South-San-Diego-Hotels-Waterpark-Hotels.0-0-d553248632063518562-tWaterparkHotels.Travel-Guide-Filter-Hotels) - [South San Diego Hotels ](https://www.expedia.ca/South-San-Diego-Hotels.d553248632063518562.Travel-Guide-Hotels) - [Vacation Homes in South San Diego ](https://www.expedia.ca/South-San-Diego-Private-Vacation-Homes.d553248632063518562-aaPrivateVacationHomes.Travel-Guide-Accommodation) - [Resorts in South San Diego ](https://www.expedia.ca/South-San-Diego-Resort-Hotels.d553248632063518562-aaResortHotels.Travel-Guide-Accommodation) - [Townhomes in South San Diego ](https://www.expedia.ca/South-San-Diego-Townhomes.d553248632063518562-aaTownhomes.Travel-Guide-Accommodation) - [Villas in South San Diego ](https://www.expedia.ca/South-San-Diego-Villas.d553248632063518562-aaVillas.Travel-Guide-Accommodation) - [Flights to San Ysidro ](https://www.expedia.ca/Cheap-Flights-To-San-Ysidro.d8380.Travel-Guide-Flights) - [Flights to South San Diego ](https://www.expedia.ca/Cheap-Flights-To-South-San-Diego.d553248632063518562.Travel-Guide-Flights) - [Flights from Chicago to South San Diego ](https://www.expedia.ca/lp/flights/178248/553248632063518562/chicago-to-south-san-diego) - [Flights from Dallas to South San Diego ](https://www.expedia.ca/lp/flights/178253/553248632063518562/dallas-to-south-san-diego) - [Flights from Nashville to South San Diego ](https://www.expedia.ca/lp/flights/178291/553248632063518562/nashville-to-south-san-diego) - [Flights from Phoenix to South San Diego ](https://www.expedia.ca/lp/flights/178298/553248632063518562/phoenix-to-south-san-diego) - [Flights from San Francisco to South San Diego ](https://www.expedia.ca/lp/flights/178305/553248632063518562/san-francisco-to-south-san-diego) - [Flights from Boise to South San Diego ](https://www.expedia.ca/lp/flights/602998/553248632063518562/boise-to-south-san-diego) - [Flights from San Ysidro ](https://www.expedia.ca/lp/flights/8380/flights-from-san-ysidro) - [Visit Nestor ](https://www.expedia.ca/San-Diego-Nestor.dx553248635976476281) - [Visit Palm City ](https://www.expedia.ca/San-Diego-Palm-City.dx553248635976470391) - [San Ysidro Vacations ](https://www.expedia.ca/San-Ysidro.d8380.Destination-Travel-Guides) - [Visit San Ysidro ](https://www.expedia.ca/San-Ysidro.dx8380) - [South San Diego Vacations ](https://www.expedia.ca/South-San-Diego.d553248632063518562.Destination-Travel-Guides) - [Budget Rental Cars in San Ysidro ](https://www.expedia.ca/Budget-Car-Rentals-In-San-Ysidro.d8380-c39.Car-Rental-Guide-Suppliers) - [Car rental San Ysidro ](https://www.expedia.ca/Car-Rentals-In-San-Ysidro.d8380.Car-Rental-Guide) - [Car rentals near South San Diego ](https://www.expedia.ca/Car-Rentals-In-South-San-Diego.d553248632063518562.Car-Rental-Guide) - [Dollar Europe Rental Cars in South San Diego ](https://www.expedia.ca/Dollar-Europe-Car-Rentals-In-South-San-Diego.d553248632063518562-c1090.Car-Rental-Guide-Suppliers) - [Island Car Rentals Rental Cars in South San Diego ](https://www.expedia.ca/Island-Car-Rentals-Car-Rentals-In-South-San-Diego.d553248632063518562-c1132.Car-Rental-Guide-Suppliers) - [Luxury Car Rentals in South San Diego ](https://www.expedia.ca/Luxury-Car-Rentals-In-South-San-Diego.d553248632063518562-tLuxury.Car-Rental-Guide-Class) - [Midway Car Rental Rental Cars in South San Diego ](https://www.expedia.ca/Midway-Car-Rental-Car-Rentals-In-South-San-Diego.d553248632063518562-c27.Car-Rental-Guide-Suppliers) - [Pickup Car Rentals in South San Diego ](https://www.expedia.ca/Pickup-Car-Rentals-In-South-San-Diego.d553248632063518562-tPickup.Car-Rental-Guide-Class) - [Priceless Car Rental Rental Cars in South San Diego ](https://www.expedia.ca/Priceless-Car-Rental-Car-Rentals-In-South-San-Diego.d553248632063518562-c1060.Car-Rental-Guide-Suppliers) - [Routes Rental Cars in South San Diego ](https://www.expedia.ca/Routes-Car-Rentals-In-South-San-Diego.d553248632063518562-c1101.Car-Rental-Guide-Suppliers) - [Things to do in San Ysidro ](https://www.expedia.ca/Things-To-Do-In-San-Ysidro.d8380.Travel-Guide-Activities) - [Book Hotels in Otay Mesa West on Expedia.com ](https://www.expedia.com/Otay-Mesa-West-San-Diego-Hotels.0-n553248625809641010-0.Travel-Guide-Filter-Hotels)