Title: Book the Best Otay Mesa West SPA Resorts from CA $155 - Spa Hotels in Otay Mesa West, San Diego | Expedia.ca [Vacation Rentals in San Diego](https://expedia.ca/San-Diego-Vacation-Rentals.d3073.Travel-Guide-VacationRentals)[Flights to San Diego](https://expedia.ca/Cheap-Flights-To-San-Diego.d3073.Travel-Guide-Flights)[Things to do in San Diego](https://expedia.ca/Things-To-Do-In-San-Diego.d3073.Travel-Guide-Activities)[Otay Mesa West Car Rentals](https://expedia.ca/Car-Rentals-In-Otay-Mesa-West.d553248625809641010.Car-Rental-Guide)[Otay Mesa West Vacations](https://expedia.ca/Otay-Mesa-West.d553248625809641010.Destination-Travel-Guides) ![](https://mediaim.expedia.com/destination/2/c82ea711c1af69b78661e7f0e8d60f0e.jpg?impolicy=fcrop&w=1200&h=500&q=medium) Photo by Leonardo De Leon # Find Spa Hotels in Otay Mesa West, San Diego from CA $155 ![](https://a.travel-assets.com/travel-assets-manager/pictogram-bex/light__calendar_shield.svg) ### Change your mind Book hotels with free cancellation ![](https://a.travel-assets.com/travel-assets-manager/pictogram-bex/light__deals.svg) ### Treat yourself Sign in to save 10% or more on thousands of hotels [Sign in](https://www.expedia.ca/login) ![](https://a.travel-assets.com/travel-assets-manager/pictogram-bex/light__bed.svg) ### Be picky Search almost a million properties worldwide ## Check availability on Otay Mesa West Spa Hotels Tonight [Oct 23 - Oct 24](https://www.expedia.ca/Hotel-Search?regionId=553248625809641010&startDate=2025-10-23&endDate=2025-10-24&adults=2&amenities=SPA_ON_SITE&rfrr=TG.LP.CheckPrices.Hotel&openPlayBack=true) Tomorrow [Oct 24 - Oct 25](https://www.expedia.ca/Hotel-Search?regionId=553248625809641010&startDate=2025-10-24&endDate=2025-10-25&adults=2&amenities=SPA_ON_SITE&rfrr=TG.LP.CheckPrices.Hotel&openPlayBack=true) This weekend [Oct 24 - Oct 26](https://www.expedia.ca/Hotel-Search?regionId=553248625809641010&startDate=2025-10-24&endDate=2025-10-26&adults=2&amenities=SPA_ON_SITE&rfrr=TG.LP.CheckPrices.Hotel&openPlayBack=true) Next weekend [Oct 31 - Nov 2](https://www.expedia.ca/Hotel-Search?regionId=553248625809641010&startDate=2025-10-31&endDate=2025-11-02&adults=2&amenities=SPA_ON_SITE&rfrr=TG.LP.CheckPrices.Hotel&openPlayBack=true) ## Top Otay Mesa West Spa Hotels ![Fitness studio](https://images.trvl-media.com/lodging/34000000/33670000/33661500/33661441/8d3908bb.jpg?impolicy=fcrop&w=357&h=201&p=1&q=medium) ![1 bedroom, hypo-allergenic bedding, down comforters, pillowtop beds](https://images.trvl-media.com/lodging/34000000/33670000/33661500/33661441/8995625e.jpg?impolicy=fcrop&w=357&h=201&p=1&q=medium) ![7 restaurants, breakfast served](https://images.trvl-media.com/lodging/34000000/33670000/33661500/33661441/250333ae.jpg?impolicy=fcrop&w=357&h=201&p=1&q=medium) ![7 restaurants, breakfast served](https://images.trvl-media.com/lodging/34000000/33670000/33661500/33661441/7910f1d4.jpg?impolicy=fcrop&w=357&h=201&p=1&q=medium) ### Sycuan Casino Resort El Cajon 9.2/10 Wonderful (1583) "Great resort!" ![United States](https://a.travel-assets.com/egds/marks/flags/us.svg) Vicky CA $126 CA $155 total includes taxes & fees Nov 19 - Nov 20 [](https://www.expedia.ca/El-Cajon-Hotels-Sycuan-Casino-Resort.h33661441.Hotel-Information) ![Reception](https://images.trvl-media.com/lodging/1000000/10000/9700/9660/8496a8ba.jpg?impolicy=fcrop&w=357&h=201&p=1&q=medium) ![Hypo-allergenic bedding, in-room safe, iron/ironing board](https://images.trvl-media.com/lodging/1000000/10000/9700/9660/3af899ba.jpg?impolicy=fcrop&w=357&h=201&p=1&q=medium) ![Hypo-allergenic bedding, in-room safe, iron/ironing board](https://images.trvl-media.com/lodging/1000000/10000/9700/9660/5c2bbbc6.jpg?impolicy=fcrop&w=357&h=201&p=1&q=medium) ![Breakfast, lunch, dinner served; Californian cuisine, pool views ](https://images.trvl-media.com/lodging/1000000/10000/9700/9660/8c14c190.jpg?impolicy=fcrop&w=357&h=201&p=1&q=medium) ### Best Western Plus Island Palms Hotel & Marina Point Loma 8.8/10 Excellent (1564) "Staff were great and friendly, good food and drink, clean and good central location. " ![Australia](https://a.travel-assets.com/egds/marks/flags/au.svg) Mick CA $170 CA $196 total includes taxes & fees Nov 23 - Nov 24 [](https://www.expedia.ca/San-Diego-Hotels-Best-Western-Plus-Island-Palms-Hotel-Marina.h9660.Hotel-Information) ![Exterior](https://images.trvl-media.com/lodging/1000000/10000/900/858/c5325c92.jpg?impolicy=fcrop&w=357&h=201&p=1&q=medium) ![Penthouse](https://images.trvl-media.com/lodging/1000000/10000/900/858/36c2b78d.jpg?impolicy=fcrop&w=357&h=201&p=1&q=medium) ![3 outdoor pools, cabanas (surcharge), pool umbrellas](https://images.trvl-media.com/lodging/1000000/10000/900/858/543624c5.jpg?impolicy=fcrop&w=357&h=201&p=1&q=medium) ![Down comforters, pillowtop beds, in-room safe, desk](https://images.trvl-media.com/lodging/1000000/10000/900/858/93b051f7.jpg?impolicy=fcrop&w=357&h=201&p=1&q=medium) ### Hyatt Regency Mission Bay Spa and Marina Mission Bay 8.4/10 Very good (1555) "Clean rooms great view amazing pool and we loved the breakfast " ![United States](https://a.travel-assets.com/egds/marks/flags/us.svg) ad CA $236 CA $346 total includes taxes & fees Oct 26 - Oct 27 [](https://www.expedia.ca/San-Diego-Hotels-Hyatt-Regency-Mission-Bay-Spa-And-Marina.h858.Hotel-Information) ![Couples treatment rooms, sauna, hot tub, steam room, body treatments](https://images.trvl-media.com/lodging/1000000/30000/25900/25840/d9cbfe80.jpg?impolicy=fcrop&w=357&h=201&p=1&q=medium) ![3 outdoor pools, cabanas (surcharge), pool umbrellas](https://images.trvl-media.com/lodging/1000000/30000/25900/25840/c2540b7d.jpg?impolicy=fcrop&w=357&h=201&p=1&q=medium) ![Staircase](https://images.trvl-media.com/lodging/1000000/30000/25900/25840/423e7241.jpg?impolicy=fcrop&w=357&h=201&p=1&q=medium) ![Exterior](https://images.trvl-media.com/lodging/1000000/30000/25900/25840/c2d82864.jpg?impolicy=fcrop&w=357&h=201&p=1&q=medium) ### Loews Coronado Bay Resort Silver Strand 8.8/10 Excellent (1045) "Beautiful quiet hotel." ![United States](https://a.travel-assets.com/egds/marks/flags/us.svg) Lori CA $278 CA $373 total includes taxes & fees Oct 26 - Oct 27 [](https://www.expedia.ca/Coronado-Hotels-Loews-Coronado-Bay-Resort.h25840.Hotel-Information) ![Outdoor pool](https://images.trvl-media.com/lodging/1000000/40000/36200/36183/7cb5b7d9.jpg?impolicy=fcrop&w=357&h=201&p=1&q=medium) ![Property grounds](https://images.trvl-media.com/lodging/1000000/40000/36200/36183/98dcc319.jpg?impolicy=fcrop&w=357&h=201&p=1&q=medium) ![Reception](https://images.trvl-media.com/lodging/1000000/40000/36200/36183/cc6aac5f.jpg?impolicy=fcrop&w=357&h=201&p=1&q=medium) ![Marina](https://images.trvl-media.com/lodging/1000000/40000/36200/36183/f0d27d94.jpg?impolicy=fcrop&w=357&h=201&p=1&q=medium) ### Humphreys Half Moon Inn Point Loma 9.2/10 Wonderful (2577) "Great hotel. " ![United States](https://a.travel-assets.com/egds/marks/flags/us.svg) Adil CA $208 CA $268 total includes taxes & fees Nov 23 - Nov 24 [](https://www.expedia.ca/San-Diego-Hotels-Humphreys-Half-Moon-Inn.h36183.Hotel-Information) ![Body treatments, aromatherapy, body wraps, body scrubs, facials](https://images.trvl-media.com/lodging/2000000/1880000/1871700/1871645/b1fc21d4.jpg?impolicy=fcrop&w=357&h=201&p=1&q=medium) ![Outdoor pool, sun loungers](https://images.trvl-media.com/lodging/2000000/1880000/1871700/1871645/9fc82331.jpg?impolicy=fcrop&w=357&h=201&p=1&q=medium) ![Breakfast, lunch, dinner served; Californian cuisine, ocean views ](https://images.trvl-media.com/lodging/2000000/1880000/1871700/1871645/06f19e3f.jpg?impolicy=fcrop&w=357&h=201&p=1&q=medium) ![2 bars/lounges, lobby lounge](https://images.trvl-media.com/lodging/2000000/1880000/1871700/1871645/ed2e1ba0.jpg?impolicy=fcrop&w=357&h=201&p=1&q=medium) ### Hilton San Diego Bayfront Downtown San Diego 8.6/10 Excellent (1790) "Clean room, beautiful views, great staff… excellent hotel and beautiful city!" ![United States](https://a.travel-assets.com/egds/marks/flags/us.svg) Kristan CA $228 CA $333 total includes taxes & fees Nov 23 - Nov 24 [](https://www.expedia.ca/San-Diego-Hotels-Hilton-San-Diego-Bayfront.h1871645.Hotel-Information) ![Couples treatment rooms, body treatments, hot stone massages](https://images.trvl-media.com/lodging/42000000/41510000/41504800/41504735/cba9a8a4.jpg?impolicy=fcrop&w=357&h=201&p=1&q=medium) ![Garden](https://images.trvl-media.com/lodging/42000000/41510000/41504800/41504735/0bbd67f4.jpg?impolicy=fcrop&w=357&h=201&p=1&q=medium) ![Premium bedding, in-room safe, desk, laptop workspace](https://images.trvl-media.com/lodging/42000000/41510000/41504800/41504735/7442075b.jpg?impolicy=fcrop&w=357&h=201&p=1&q=medium) ![Lobby](https://images.trvl-media.com/lodging/42000000/41510000/41504800/41504735/43ef19cb.jpg?impolicy=fcrop&w=357&h=201&p=1&q=medium) ### Legacy Resort Hotel & Spa Mission Valley 9.2/10 Wonderful (2898) "Love this hotel. " ![United States](https://a.travel-assets.com/egds/marks/flags/us.svg) Dana CA $225 CA $259 total includes taxes & fees Oct 26 - Oct 27 [](https://www.expedia.ca/San-Diego-Hotels-Legacy-Resort-Hotel-Spa.h41504735.Hotel-Information) ![Premier Room, 1 King Bed](https://images.trvl-media.com/lodging/1000000/10000/8400/8374/fde0003f.jpg?impolicy=fcrop&w=357&h=201&p=1&q=medium) ![Outdoor pool, pool umbrellas, sun loungers](https://images.trvl-media.com/lodging/1000000/10000/8400/8374/ab6ccd55.jpg?impolicy=fcrop&w=357&h=201&p=1&q=medium) ![Premium bedding, in-room safe, desk, blackout drapes](https://images.trvl-media.com/lodging/1000000/10000/8400/8374/76794add.jpg?impolicy=fcrop&w=357&h=201&p=1&q=medium) ![2 bars/lounges, poolside bar](https://images.trvl-media.com/lodging/1000000/10000/8400/8374/cc4883a7.jpg?impolicy=fcrop&w=357&h=201&p=1&q=medium) ### Handlery Hotel Mission Valley 8.2/10 Very good (2157) "The hotel is very clean, pool and spa are fantastic, the food at the hotel was excellent " ![United States](https://a.travel-assets.com/egds/marks/flags/us.svg) Eugene CA $143 CA $164 total includes taxes & fees Oct 26 - Oct 27 [](https://www.expedia.ca/San-Diego-Hotels-Handlery-Hotel.h8374.Hotel-Information) ![Spa](https://images.trvl-media.com/lodging/1000000/30000/25600/25598/25a004df.jpg?impolicy=fcrop&w=357&h=201&p=1&q=medium) ![Premium bedding, down comforters, pillowtop beds, in-room safe](https://images.trvl-media.com/lodging/1000000/30000/25600/25598/c2cecb91.jpg?impolicy=fcrop&w=357&h=201&p=1&q=medium) ![2 restaurants, breakfast, lunch, dinner served; American cuisine](https://images.trvl-media.com/lodging/1000000/30000/25600/25598/de48676b.jpg?impolicy=fcrop&w=357&h=201&p=1&q=medium) ![On the beach, white sand, windsurfing, beach volleyball](https://images.trvl-media.com/lodging/1000000/30000/25600/25598/c20f7d47.jpg?impolicy=fcrop&w=357&h=201&p=1&q=medium) ### San Diego Mission Bay Resort Mission Bay 8.4/10 Very good (1281) "Very clean resort" ![United States](https://a.travel-assets.com/egds/marks/flags/us.svg) Jesse CA $278 CA $383 total includes taxes & fees Oct 27 - Oct 28 [](https://www.expedia.ca/San-Diego-Hotels-San-Diego-Mission-Bay-Resort.h25598.Hotel-Information) ![Exterior](https://images.trvl-media.com/lodging/1000000/580000/570900/570818/ef17b3e7.jpg?impolicy=fcrop&w=357&h=201&p=1&q=medium) ![Point of interest](https://images.trvl-media.com/lodging/1000000/580000/570900/570818/5d6482eb.jpg?impolicy=fcrop&w=357&h=201&p=1&q=medium) ![Lobby](https://images.trvl-media.com/lodging/1000000/580000/570900/570818/743ac288.jpg?impolicy=fcrop&w=357&h=201&p=1&q=medium) ![Lobby](https://images.trvl-media.com/lodging/1000000/580000/570900/570818/e7aa7734.jpg?impolicy=fcrop&w=357&h=201&p=1&q=medium) ### Pier South Resort, Autograph Collection by Marriott Imperial Beach 8.4/10 Very good (1005) "Staff members were very helpful and friendly " ![United States](https://a.travel-assets.com/egds/marks/flags/us.svg) Dale CA $231 CA $295 total includes taxes & fees Nov 2 - Nov 3 [](https://www.expedia.ca/Imperial-Beach-Hotels-Pier-South-Resort.h570818.Hotel-Information) Lowest nightly price found within the past 24 hours based on a 1 night stay for 2 adults. Prices and availability subject to change. Additional terms may apply. [View all properties](https://expedia.ca/Hotel-Search?startDate=2025-11-06&endDate=2025-11-07®ionId=553248625809641010&adults=2&amenities=SPA_ON_SITE&sort=RECOMMENDED&openPlayBack=true) ## Top Otay Mesa West Hotel Reviews ![Hampton Inn & Suites by Hilton San Diego SeaWorld](//images.trvl-media.com/lodging/13000000/12970000/12963400/12963301/cc52443d_y.jpg) ### Hampton Inn & Suites by Hilton San Diego SeaWorld 10/10 Excellent "The breakfast was great we enjoyed the hot tub and the pool" [](https://expedia.ca/San-Diego-Hotels-Hampton-Inn-Suites-San-Diego-Point-Loma.h12963301.Hotel-Information) ![Hotel del Coronado, Curio Collection by Hilton](//images.trvl-media.com/lodging/1000000/10000/7500/7496/20fe4d95_y.jpg) ### Hotel del Coronado, Curio Collection by Hilton 10/10 Excellent "Beach view from our balcony was breathtaking. We were able to see the ocean as well as the entire outdoor Coronado pool/outdoor service area. Hotel an easy walk to local shops/food. Great place w lots of history and charm." [](https://expedia.ca/Coronado-Hotels-Hotel-Del-Coronado.h7496.Hotel-Information) ![The Dana on Mission Bay](//images.trvl-media.com/lodging/1000000/50000/41000/40953/08585098_y.jpg) ### The Dana on Mission Bay 10/10 Excellent "Great View, close to the concert!" [](https://expedia.ca/San-Diego-Hotels-The-Dana-On-Mission-Bay.h40953.Hotel-Information) ![Pendry San Diego](//images.trvl-media.com/lodging/17000000/16300000/16299000/16298963/05d0e601_y.jpg) ### Pendry San Diego 10/10 Excellent "The rooms were very nice and the location is perfect for San Diego. It's a very nice hotel." [](https://expedia.ca/San-Diego-Hotels-Pendry-San-Diego.h16298963.Hotel-Information) ![Wyndham San Diego Bayside](//images.trvl-media.com/lodging/1000000/20000/11200/11177/c44ff51d_y.jpg) ### Wyndham San Diego Bayside 10/10 Excellent "Older property but great location. Friendly staff and lots nearby. " [](https://expedia.ca/San-Diego-Hotels-Wyndham-San-Diego-Bayside.h11177.Hotel-Information) ![Courtyard by Marriott San Diego Downtown Little Italy](//images.trvl-media.com/lodging/1000000/20000/13300/13205/0339a25b_y.jpg) ### Courtyard by Marriott San Diego Downtown Little Italy 10/10 Excellent "Amazing staff! From front desk to dinning and bar area! Safe area, walking distance to restaurants " [](https://expedia.ca/San-Diego-Hotels-The-Little-Italy-Hotel-In-Downtown-San-Diego.h13205.Hotel-Information) ![Manchester Grand Hyatt San Diego](//images.trvl-media.com/lodging/1000000/20000/12100/12073/w3840h2092x0y3-447c77a4_y.jpg) ### Manchester Grand Hyatt San Diego 10/10 Excellent "The hotel is beautiful and conveniently located near Seaport Village, offering everything you need within walking distance. You and your family can fully enjoy your stay without having to venture far—Seaport Village and the hotel itself provide plenty to experience. The dining options are both affordable and excellent. There is truly no better hotel to choose from." [](https://expedia.ca/San-Diego-Hotels-Manchester-Grand-Hyatt-San-Diego.h12073.Hotel-Information) ![Hilton San Diego Mission Valley](//images.trvl-media.com/lodging/1000000/20000/16100/16019/w3839h2160x1y0-98566ca3_y.jpg) ### Hilton San Diego Mission Valley 10/10 Excellent "Super easy check in process, staff was extremely hospitable. My room was comfortable as well. Great job Hilton" [](https://expedia.ca/San-Diego-Hotels-Hilton-San-Diego-Mission-Valley.h16019.Hotel-Information) ![Days Inn by Wyndham San Diego Hotel Circle](//images.trvl-media.com/lodging/1000000/20000/19300/19220/3334d773_y.jpg) ### Days Inn by Wyndham San Diego Hotel Circle 10/10 Excellent "Great for the price" [](https://expedia.ca/San-Diego-Hotels-Days-Inn-By-Wyndham-San-Diego-Hotel-Circle.h19220.Hotel-Information) ## Frequently asked questions ### Looking to vacation at a spa hotel in Otay Mesa West? > Book one of our wonderful spa hotels and treat yourself from the moment you arrive. Check out the cathedral in Otay Mesa West—your cultural tour starts here. Spa hotels are the perfect way to break away from your routine and add a layer of luxury to your holiday. ### What's there to see and do in Otay Mesa West? > Experience all that Otay Mesa West has to offer when you visit San Diego Zoo, Mission Bay, and San Ysidro Border Crossing. If you have a little extra time during your trip, you might want to check out Hotel del Coronado and Petco Park. ### What is a Otay Mesa West spa hotel? > Spa hotels in Otay Mesa West provide lodging and have an on-site spa offering services including couples massages and beauty treatments. Some also offer in-room treatments. Spa hotels are great for rest, rejuvenation, and relaxation. ## Explore a world of travel with Expedia - Lodging - More ways to book - [Beach Hotel Hotels in Camp Pendleton Marine Corps Base](https://www.expedia.ca/Camp-Pendleton-Marine-Corps-Base-Hotels-Beach-Hotel.0-0-d6068523-tBeachHotel.Travel-Guide-Filter-Hotels) - [Hotels with an Indoor Pool in Camp Pendleton Marine Corps Base](https://www.expedia.ca/Camp-Pendleton-Marine-Corps-Base-Hotels-Hotels-With-Indoor-Pool.0-0-d6068523-tHotelswithIndoorPool.Travel-Guide-Filter-Hotels) - [Oceanfront Hotels in Camp Pendleton Marine Corps Base](https://www.expedia.ca/Camp-Pendleton-Marine-Corps-Base-Hotels-Oceanfront-Hotels.0-0-d6068523-tOceanfrontHotels.Travel-Guide-Filter-Hotels) - [Ski Hotels in Camp Pendleton Marine Corps Base](https://www.expedia.ca/Camp-Pendleton-Marine-Corps-Base-Hotels-Ski-Hotel.0-0-d6068523-tSkiHotel.Travel-Guide-Filter-Hotels) - [Hotels & Resorts for Couples in Carlsbad](https://www.expedia.ca/Carlsbad-Hotels-Couples-Resorts-Hotels.0-0-d6056550-tCouplesResortsHotels.Travel-Guide-Filter-Hotels) - [Hotels with Early Check-in in Carlsbad](https://www.expedia.ca/Carlsbad-Hotels-Hotel-With-Early-Check-In.0-0-d6056550-thotelwithearlycheckin.Travel-Guide-Filter-Hotels) - [Hotels with Hot Tubs in Carlsbad](https://www.expedia.ca/Carlsbad-Hotels-Hotels-With-Hot-Tubs.0-0-d6056550-tHotelsWithHotTubs.Travel-Guide-Filter-Hotels) - [Lake Hotels in Carlsbad](https://www.expedia.ca/Carlsbad-Hotels-Lake-Hotels.0-0-d6056550-tLakeHotels.Travel-Guide-Filter-Hotels) - [Scuba Diving Hotels in Carlsbad](https://www.expedia.ca/Carlsbad-Hotels-Scuba-Diving-Vacations.0-0-d6056550-tscubadivingvacations.Travel-Guide-Filter-Hotels) - [Winery Hotels in Carlsbad](https://www.expedia.ca/Carlsbad-Hotels-Winery-Hotel.0-0-d6056550-tWineryHotel.Travel-Guide-Filter-Hotels) - [Casino Hotels in Chula Vista](https://www.expedia.ca/Chula-Vista-Hotels-Casino-Hotel.0-0-d7442-tCasinoHotel.Travel-Guide-Filter-Hotels) - [Hotels with Hot Tubs in Chula Vista](https://www.expedia.ca/Chula-Vista-Hotels-Hotels-With-Hot-Tubs.0-0-d7442-tHotelsWithHotTubs.Travel-Guide-Filter-Hotels) - [Spa Hotels in Chula Vista](https://www.expedia.ca/Chula-Vista-Hotels-Spa-Hotel.0-0-d7442-tSpaHotel.Travel-Guide-Filter-Hotels) - [Green Hotels in San Diego County](https://www.expedia.ca/Destinations-In-San-Diego-County-Green-Sustainable.0-0-d178304-tGreenSustainable.Hotel-Filter-Destinations) - [Hotels with Wifi in San Diego County](https://www.expedia.ca/Destinations-In-San-Diego-County-Hotel-With-Wifi.0-0-d178304-tHotelwithwifi.Hotel-Filter-Destinations) - [Hotels with Bar in San Diego County](https://www.expedia.ca/Destinations-In-San-Diego-County-Hotels-With-Bar.0-0-d178304-tHotelswithBar.Hotel-Filter-Destinations) - [Hotels with Childcare in San Diego County](https://www.expedia.ca/Destinations-In-San-Diego-County-Hotels-With-Childcare.0-0-d178304-tHotelswithChildcare.Hotel-Filter-Destinations) - [Hotels with Free Breakfast in San Diego County](https://www.expedia.ca/Destinations-In-San-Diego-County-Hotels-With-Free-Breakfast.0-0-d178304-tHotelswithFreeBreakfast.Hotel-Filter-Destinations) - [Hotels with Free Parking in San Diego County](https://www.expedia.ca/Destinations-In-San-Diego-County-Hotels-With-Free-Parking.0-0-d178304-tHotelswithFreeParking.Hotel-Filter-Destinations) - [Hotels with Hot Tubs in San Diego County](https://www.expedia.ca/Destinations-In-San-Diego-County-Hotels-With-Hot-Tubs.0-0-d178304-tHotelsWithHotTubs.Hotel-Filter-Destinations) - [Hotels with smoking rooms in San Diego County](https://www.expedia.ca/Destinations-In-San-Diego-County-Hotels-With-Smoking-Rooms.0-0-d178304-tHotelswithsmokingrooms.Hotel-Filter-Destinations) - [Lgbt Friendly Hotels in San Diego County](https://www.expedia.ca/Destinations-In-San-Diego-County-LGBT-Friendly-Hotel.0-0-d178304-tLGBTFriendlyHotel.Hotel-Filter-Destinations) - [Scuba Diving Hotels in San Diego County](https://www.expedia.ca/Destinations-In-San-Diego-County-Scuba-Diving-Vacations.0-0-d178304-tscubadivingvacations.Hotel-Filter-Destinations) - [Shopping Hotels in San Diego County](https://www.expedia.ca/Destinations-In-San-Diego-County-Shopping-Hotel.0-0-d178304-tShoppingHotel.Hotel-Filter-Destinations) - [Hotel Wedding Venues Hotels in San Diego County](https://www.expedia.ca/Destinations-In-San-Diego-County-Wedding-Hotels.0-0-d178304-tWeddingHotels.Hotel-Filter-Destinations) - [Adults Only Resorts & in Downtown San Diego](https://www.expedia.ca/Downtown-San-Diego-San-Diego-Hotels-Adults-Only-Resorts.0-n800123-0-tAdultsOnlyResorts.Travel-Guide-Filter-Hotels) - [Hotels & Resorts for Couples in Downtown San Diego](https://www.expedia.ca/Downtown-San-Diego-San-Diego-Hotels-Couples-Resorts-Hotels.0-n800123-0-tCouplesResortsHotels.Travel-Guide-Filter-Hotels) - [Golf Hotels in Downtown San Diego](https://www.expedia.ca/Downtown-San-Diego-San-Diego-Hotels-Golf-Hotel.0-n800123-0-tGolfHotel.Travel-Guide-Filter-Hotels) - [Hotels with Wifi in Downtown San Diego](https://www.expedia.ca/Downtown-San-Diego-San-Diego-Hotels-Hotel-With-Wifi.0-n800123-0-tHotelwithwifi.Travel-Guide-Filter-Hotels) - [Hotels with a Lazy River in Downtown San Diego](https://www.expedia.ca/Downtown-San-Diego-San-Diego-Hotels-Hotels-With-A-Lazy-River.0-n800123-0-tHotelswithaLazyRiver.Travel-Guide-Filter-Hotels) - [Hotels with Balconies in Downtown San Diego](https://www.expedia.ca/Downtown-San-Diego-San-Diego-Hotels-Hotels-With-Balconies.0-n800123-0-tHotelswithBalconies.Travel-Guide-Filter-Hotels) - [Hotels with Bar in Downtown San Diego](https://www.expedia.ca/Downtown-San-Diego-San-Diego-Hotels-Hotels-With-Bar.0-n800123-0-tHotelswithBar.Travel-Guide-Filter-Hotels) - [Hotels with Free Breakfast in Downtown San Diego](https://www.expedia.ca/Downtown-San-Diego-San-Diego-Hotels-Hotels-With-Free-Breakfast.0-n800123-0-tHotelswithFreeBreakfast.Travel-Guide-Filter-Hotels) - [Hotels with Hot Tubs in Downtown San Diego](https://www.expedia.ca/Downtown-San-Diego-San-Diego-Hotels-Hotels-With-Hot-Tubs.0-n800123-0-tHotelsWithHotTubs.Travel-Guide-Filter-Hotels) - [Hotels with an Indoor Pool in Downtown San Diego](https://www.expedia.ca/Downtown-San-Diego-San-Diego-Hotels-Hotels-With-Indoor-Pool.0-n800123-0-tHotelswithIndoorPool.Travel-Guide-Filter-Hotels) - [Lgbt Friendly Hotels in Downtown San Diego](https://www.expedia.ca/Downtown-San-Diego-San-Diego-Hotels-LGBT-Friendly-Hotel.0-n800123-0-tLGBTFriendlyHotel.Travel-Guide-Filter-Hotels) - [Lake Hotels in Downtown San Diego](https://www.expedia.ca/Downtown-San-Diego-San-Diego-Hotels-Lake-Hotels.0-n800123-0-tLakeHotels.Travel-Guide-Filter-Hotels) - [Mountain Hotels in Downtown San Diego](https://www.expedia.ca/Downtown-San-Diego-San-Diego-Hotels-Mountain-Hotels.0-n800123-0-tMountainHotels.Travel-Guide-Filter-Hotels) - [Romantic Hotels in Downtown San Diego](https://www.expedia.ca/Downtown-San-Diego-San-Diego-Hotels-Romantic-Hotel.0-n800123-0-tRomanticHotel.Travel-Guide-Filter-Hotels) - [Scuba Diving Hotels in Downtown San Diego](https://www.expedia.ca/Downtown-San-Diego-San-Diego-Hotels-Scuba-Diving-Vacations.0-n800123-0-tscubadivingvacations.Travel-Guide-Filter-Hotels) - [Shopping Hotels in Downtown San Diego](https://www.expedia.ca/Downtown-San-Diego-San-Diego-Hotels-Shopping-Hotel.0-n800123-0-tShoppingHotel.Travel-Guide-Filter-Hotels) - [Spa Hotels in Downtown San Diego](https://www.expedia.ca/Downtown-San-Diego-San-Diego-Hotels-Spa-Hotel.0-n800123-0-tSpaHotel.Travel-Guide-Filter-Hotels) - [Waterpark Hotels in Downtown San Diego](https://www.expedia.ca/Downtown-San-Diego-San-Diego-Hotels-Waterpark-Hotels.0-n800123-0-tWaterparkHotels.Travel-Guide-Filter-Hotels) - [Winery Hotels in Downtown San Diego](https://www.expedia.ca/Downtown-San-Diego-San-Diego-Hotels-Winery-Hotel.0-n800123-0-tWineryHotel.Travel-Guide-Filter-Hotels) - [Green Hotels in Gaslamp Quarter](https://www.expedia.ca/Gaslamp-Quarter-San-Diego-Hotels-Green-Sustainable.0-n6130021-0-tGreenSustainable.Travel-Guide-Filter-Hotels) - [Hotels with Bar in Gaslamp Quarter](https://www.expedia.ca/Gaslamp-Quarter-San-Diego-Hotels-Hotels-With-Bar.0-n6130021-0-tHotelswithBar.Travel-Guide-Filter-Hotels) - [Waterpark Hotels in Gaslamp Quarter](https://www.expedia.ca/Gaslamp-Quarter-San-Diego-Hotels-Waterpark-Hotels.0-n6130021-0-tWaterparkHotels.Travel-Guide-Filter-Hotels) - [All Inclusive Resorts and in Ocean View Hills](https://www.expedia.ca/Ocean-View-Hills-San-Diego-Hotels-All-Inclusive-Hotel.0-n553248635976008220-0-tAllInclusiveHotel.Travel-Guide-Filter-Hotels) - [Beach Hotel Hotels in Ocean View Hills](https://www.expedia.ca/Ocean-View-Hills-San-Diego-Hotels-Beach-Hotel.0-n553248635976008220-0-tBeachHotel.Travel-Guide-Filter-Hotels) - [Hotels with Hot Tubs in Ocean View Hills](https://www.expedia.ca/Ocean-View-Hills-San-Diego-Hotels-Hotels-With-Hot-Tubs.0-n553248635976008220-0-tHotelsWithHotTubs.Travel-Guide-Filter-Hotels) - [Oceanfront Hotels in Ocean View Hills](https://www.expedia.ca/Ocean-View-Hills-San-Diego-Hotels-Oceanfront-Hotels.0-n553248635976008220-0-tOceanfrontHotels.Travel-Guide-Filter-Hotels) - [Hotel Wedding Venues Hotels in Ocean View Hills](https://www.expedia.ca/Ocean-View-Hills-San-Diego-Hotels-Wedding-Hotels.0-n553248635976008220-0-tWeddingHotels.Travel-Guide-Filter-Hotels) - [Historic Hotels in Oceanside](https://www.expedia.ca/Oceanside-Hotels-Historic-Hotel.0-0-d9154-tHistoricHotel.Travel-Guide-Filter-Hotels) - [Hotels with Balconies in Oceanside](https://www.expedia.ca/Oceanside-Hotels-Hotels-With-Balconies.0-0-d9154-tHotelswithBalconies.Travel-Guide-Filter-Hotels) - [Hotels with Hot Tubs in Oceanside](https://www.expedia.ca/Oceanside-Hotels-Hotels-With-Hot-Tubs.0-0-d9154-tHotelsWithHotTubs.Travel-Guide-Filter-Hotels) - [Business Hotels in Otay](https://www.expedia.ca/Otay-Chula-Vista-Hotels-Business-Hotel.0-n177685-0-tBusinessHotel.Travel-Guide-Filter-Hotels) - [Oceanfront Hotels in Otay](https://www.expedia.ca/Otay-Chula-Vista-Hotels-Oceanfront-Hotels.0-n177685-0-tOceanfrontHotels.Travel-Guide-Filter-Hotels) - [Pet-Friendly Hotels in Otay](https://www.expedia.ca/Otay-Chula-Vista-Hotels-Pet-Friendly-Hotel.0-n177685-0-tPetfriendlyHotel.Travel-Guide-Filter-Hotels) - [Beach Hotel Hotels in Otay Mesa](https://www.expedia.ca/Otay-Mesa-San-Diego-Hotels-Beach-Hotel.0-n6263723-0-tBeachHotel.Travel-Guide-Filter-Hotels) - [Oceanfront Hotels in Otay Mesa](https://www.expedia.ca/Otay-Mesa-San-Diego-Hotels-Oceanfront-Hotels.0-n6263723-0-tOceanfrontHotels.Travel-Guide-Filter-Hotels) - [Spa Hotels in Otay Mesa](https://www.expedia.ca/Otay-Mesa-San-Diego-Hotels-Spa-Hotel.0-n6263723-0-tSpaHotel.Travel-Guide-Filter-Hotels) - [Cheap Hotels in San Diego Coast](https://www.expedia.ca/San-Diego-Coast-Hotels-Cheap-Hotels.0-0-d553248633966884021-tCheapHotels.Travel-Guide-Filter-Hotels) - [Family Hotels in San Diego Coast](https://www.expedia.ca/San-Diego-Coast-Hotels-Family-Hotel.0-0-d553248633966884021-tFamilyHotel.Travel-Guide-Filter-Hotels) - [Green Hotels in San Diego Coast](https://www.expedia.ca/San-Diego-Coast-Hotels-Green-Sustainable.0-0-d553248633966884021-tGreenSustainable.Travel-Guide-Filter-Hotels) - [Hotels with Hot Tubs in San Diego Coast](https://www.expedia.ca/San-Diego-Coast-Hotels-Hotels-With-Hot-Tubs.0-0-d553248633966884021-tHotelsWithHotTubs.Travel-Guide-Filter-Hotels) - [Lake Hotels in San Diego Coast](https://www.expedia.ca/San-Diego-Coast-Hotels-Lake-Hotels.0-0-d553248633966884021-tLakeHotels.Travel-Guide-Filter-Hotels) - [Business Hotels in San Diego](https://www.expedia.ca/San-Diego-Hotels-Business-Hotel.0-0-d3073-tBusinessHotel.Travel-Guide-Filter-Hotels) - [Casino Hotels in San Diego](https://www.expedia.ca/San-Diego-Hotels-Casino-Hotel.0-0-d3073-tCasinoHotel.Travel-Guide-Filter-Hotels) - [Hotels & Resorts for Couples in San Diego](https://www.expedia.ca/San-Diego-Hotels-Couples-Resorts-Hotels.0-0-d3073-tCouplesResortsHotels.Travel-Guide-Filter-Hotels) - [Golf Hotels in San Diego](https://www.expedia.ca/San-Diego-Hotels-Golf-Hotel.0-0-d3073-tGolfHotel.Travel-Guide-Filter-Hotels) - [Green Hotels in San Diego](https://www.expedia.ca/San-Diego-Hotels-Green-Sustainable.0-0-d3073-tGreenSustainable.Travel-Guide-Filter-Hotels) - [Historic Hotels in San Diego](https://www.expedia.ca/San-Diego-Hotels-Historic-Hotel.0-0-d3073-tHistoricHotel.Travel-Guide-Filter-Hotels) - [Hotels with Wifi in San Diego](https://www.expedia.ca/San-Diego-Hotels-Hotel-With-Wifi.0-0-d3073-tHotelwithwifi.Travel-Guide-Filter-Hotels) - [Hotels with Bar in San Diego](https://www.expedia.ca/San-Diego-Hotels-Hotels-With-Bar.0-0-d3073-tHotelswithBar.Travel-Guide-Filter-Hotels) - [Hotels with Hot Tubs in San Diego](https://www.expedia.ca/San-Diego-Hotels-Hotels-With-Hot-Tubs.0-0-d3073-tHotelsWithHotTubs.Travel-Guide-Filter-Hotels) - [Lake Hotels in San Diego](https://www.expedia.ca/San-Diego-Hotels-Lake-Hotels.0-0-d3073-tLakeHotels.Travel-Guide-Filter-Hotels) - [Scuba Diving Hotels in San Diego](https://www.expedia.ca/San-Diego-Hotels-Scuba-Diving-Vacations.0-0-d3073-tscubadivingvacations.Travel-Guide-Filter-Hotels) - [Hotel Wedding Venues Hotels in San Diego](https://www.expedia.ca/San-Diego-Hotels-Wedding-Hotels.0-0-d3073-tWeddingHotels.Travel-Guide-Filter-Hotels) - [Boutique Hotels in San Ysidro](https://www.expedia.ca/San-Ysidro-Hotels-Boutique-Hotel.0-0-d8380-tBoutiqueHotel.Travel-Guide-Filter-Hotels) - [Business Hotels in San Ysidro](https://www.expedia.ca/San-Ysidro-Hotels-Business-Hotel.0-0-d8380-tBusinessHotel.Travel-Guide-Filter-Hotels) - [Cheap Hotels in San Ysidro](https://www.expedia.ca/San-Ysidro-Hotels-Cheap-Hotels.0-0-d8380-tCheapHotels.Travel-Guide-Filter-Hotels) - [Hotels & Resorts for Couples in San Ysidro](https://www.expedia.ca/San-Ysidro-Hotels-Couples-Resorts-Hotels.0-0-d8380-tCouplesResortsHotels.Travel-Guide-Filter-Hotels) - [Hotels with Early Check-in in San Ysidro](https://www.expedia.ca/San-Ysidro-Hotels-Hotel-With-Early-Check-In.0-0-d8380-thotelwithearlycheckin.Travel-Guide-Filter-Hotels) - [Hotels with Free Airport Shuttle in San Ysidro](https://www.expedia.ca/San-Ysidro-Hotels-Hotels-With-Free-Airport-Shuttle.0-0-d8380-tHotelswithFreeAirportShuttle.Travel-Guide-Filter-Hotels) - [Luxury Hotels in San Ysidro](https://www.expedia.ca/San-Ysidro-Hotels-Luxury-Hotel.0-0-d8380-tLuxuryHotel.Travel-Guide-Filter-Hotels) - [Pet-Friendly Hotels in San Ysidro](https://www.expedia.ca/San-Ysidro-Hotels-Pet-Friendly-Hotel.0-0-d8380-tPetfriendlyHotel.Travel-Guide-Filter-Hotels) - [Winery Hotels in San Ysidro](https://www.expedia.ca/San-Ysidro-Hotels-Winery-Hotel.0-0-d8380-tWineryHotel.Travel-Guide-Filter-Hotels) - [Beach Hotel Hotels in South San Diego](https://www.expedia.ca/South-San-Diego-Hotels-Beach-Hotel.0-0-d553248632063518562-tBeachHotel.Travel-Guide-Filter-Hotels) - [Boutique Hotels in South San Diego](https://www.expedia.ca/South-San-Diego-Hotels-Boutique-Hotel.0-0-d553248632063518562-tBoutiqueHotel.Travel-Guide-Filter-Hotels) - [Cheap Hotels in South San Diego](https://www.expedia.ca/South-San-Diego-Hotels-Cheap-Hotels.0-0-d553248632063518562-tCheapHotels.Travel-Guide-Filter-Hotels) - [Hotels & Resorts for Couples in South San Diego](https://www.expedia.ca/South-San-Diego-Hotels-Couples-Resorts-Hotels.0-0-d553248632063518562-tCouplesResortsHotels.Travel-Guide-Filter-Hotels) - [Family Hotels in South San Diego](https://www.expedia.ca/South-San-Diego-Hotels-Family-Hotel.0-0-d553248632063518562-tFamilyHotel.Travel-Guide-Filter-Hotels) - [Hotels with a Pool in South San Diego](https://www.expedia.ca/South-San-Diego-Hotels-Hotel-With-Pool.0-0-d553248632063518562-tHotelwithPool.Travel-Guide-Filter-Hotels) - [Hotels with Bar in South San Diego](https://www.expedia.ca/South-San-Diego-Hotels-Hotels-With-Bar.0-0-d553248632063518562-tHotelswithBar.Travel-Guide-Filter-Hotels) - [Hotels with Free Breakfast in South San Diego](https://www.expedia.ca/South-San-Diego-Hotels-Hotels-With-Free-Breakfast.0-0-d553248632063518562-tHotelswithFreeBreakfast.Travel-Guide-Filter-Hotels) - [Hotels with Hot Tubs in South San Diego](https://www.expedia.ca/South-San-Diego-Hotels-Hotels-With-Hot-Tubs.0-0-d553248632063518562-tHotelsWithHotTubs.Travel-Guide-Filter-Hotels) - [Hotels with Kitchenettes in South San Diego](https://www.expedia.ca/South-San-Diego-Hotels-Hotels-With-Kitchenettes.0-0-d553248632063518562-tHotelswithKitchenettes.Travel-Guide-Filter-Hotels) - [Oceanfront Hotels in South San Diego](https://www.expedia.ca/South-San-Diego-Hotels-Oceanfront-Hotels.0-0-d553248632063518562-tOceanfrontHotels.Travel-Guide-Filter-Hotels) - [Spa Hotels in South San Diego](https://www.expedia.ca/South-San-Diego-Hotels-Spa-Hotel.0-0-d553248632063518562-tSpaHotel.Travel-Guide-Filter-Hotels) - [Waterpark Hotels in South San Diego](https://www.expedia.ca/South-San-Diego-Hotels-Waterpark-Hotels.0-0-d553248632063518562-tWaterparkHotels.Travel-Guide-Filter-Hotels) - [Book Hotels in Otay Mesa West on Expedia.com](https://www.expedia.com/Otay-Mesa-West-San-Diego-Hotels-Spa-Hotel.0-n553248625809641010-0-tSpaHotel.Travel-Guide-Filter-Hotels)