Title: Book the Best PET FRIENDLY Hotels in Otay Mesa West, San Diego from CA $127 - Otay Mesa West Dog-Friendly Hotels | Expedia.ca [Vacation Rentals in San Diego](https://expedia.ca/San-Diego-Vacation-Rentals.d3073.Travel-Guide-VacationRentals)[Flights to San Diego](https://expedia.ca/Cheap-Flights-To-San-Diego.d3073.Travel-Guide-Flights)[Things to do in San Diego](https://expedia.ca/Things-To-Do-In-San-Diego.d3073.Travel-Guide-Activities)[Otay Mesa West Car Rentals](https://expedia.ca/Car-Rentals-In-Otay-Mesa-West.d553248625809641010.Car-Rental-Guide)[Otay Mesa West Vacations](https://expedia.ca/Otay-Mesa-West.d553248625809641010.Destination-Travel-Guides) ![Default HTG hotel image](https://a.travel-assets.com/travel-assets-manager/bex-affinities/pet_friendly.jpeg?impolicy=fcrop&w=1200&h=500&q=medium) # Find Pet-friendly Hotels in Otay Mesa West, San Diego from CA $127 - ![](https://a.travel-assets.com/travel-assets-manager/pictogram-bex/light__calendar_shield.svg) ### Change your mind Book hotels with free cancellation - ![](https://a.travel-assets.com/travel-assets-manager/pictogram-bex/light__deals.svg) ### Treat yourself Sign in to save 10% or more on thousands of hotels [Sign in](https://www.expedia.ca/login) - ![](https://a.travel-assets.com/travel-assets-manager/pictogram-bex/light__bed.svg) ### Be picky Search almost a million properties worldwide ## Check availability on Otay Mesa West Pet-friendly Hotels Tonight [Dec 3 - Dec 4](https://www.expedia.ca/Hotel-Search?regionId=553248625809641010&startDate=2025-12-03&endDate=2025-12-04&adults=2&amenities=PETS&rfrr=TG.LP.CheckPrices.Hotel&openPlayBack=true) Tomorrow [Dec 4 - Dec 5](https://www.expedia.ca/Hotel-Search?regionId=553248625809641010&startDate=2025-12-04&endDate=2025-12-05&adults=2&amenities=PETS&rfrr=TG.LP.CheckPrices.Hotel&openPlayBack=true) This weekend [Dec 5 - Dec 7](https://www.expedia.ca/Hotel-Search?regionId=553248625809641010&startDate=2025-12-05&endDate=2025-12-07&adults=2&amenities=PETS&rfrr=TG.LP.CheckPrices.Hotel&openPlayBack=true) Next weekend [Dec 12 - Dec 14](https://www.expedia.ca/Hotel-Search?regionId=553248625809641010&startDate=2025-12-12&endDate=2025-12-14&adults=2&amenities=PETS&rfrr=TG.LP.CheckPrices.Hotel&openPlayBack=true) ## Top Otay Mesa West Pet-friendly Hotels ![Lobby](https://images.trvl-media.com/lodging/1000000/900000/898500/898447/e9d3f965.jpg?impolicy=fcrop&w=357&h=201&p=1&q=medium) ![Exterior](https://images.trvl-media.com/lodging/1000000/900000/898500/898447/fcaa8786.jpg?impolicy=fcrop&w=357&h=201&p=1&q=medium) ![Meeting facility](https://images.trvl-media.com/lodging/1000000/900000/898500/898447/de4da698.jpg?impolicy=fcrop&w=357&h=201&p=1&q=medium) ![Premium bedding, down comforters, pillowtop beds, in-room safe](https://images.trvl-media.com/lodging/1000000/900000/898500/898447/8f9c8a5a.jpg?impolicy=fcrop&w=357&h=201&p=1&q=medium) ### Hotel Republic San Diego, Autograph Collection Downtown San Diego 9.0/10 Wonderful (1187) "Amazing stay " ![United States](https://a.travel-assets.com/egds/marks/flags/us.svg) Aaron CA $161 CA $252 total includes taxes & fees Dec 19 - Dec 20 [](https://www.expedia.ca/San-Diego-Hotels-Hotel-Republic-San-Diego.h898447.Hotel-Information) ![Seasonal outdoor pool, a heated pool](https://images.trvl-media.com/lodging/2000000/1050000/1047500/1047474/0c3fb187.jpg?impolicy=fcrop&w=357&h=201&p=1&q=medium) ![Property grounds](https://images.trvl-media.com/lodging/2000000/1050000/1047500/1047474/27276731.jpg?impolicy=fcrop&w=357&h=201&p=1&q=medium) ![Pet-friendly](https://images.trvl-media.com/lodging/2000000/1050000/1047500/1047474/aac48c50.jpg?impolicy=fcrop&w=357&h=201&p=1&q=medium) ![Premium Room, 1 King Bed, Non Smoking, Ocean View (Non-Pet friendly)](https://images.trvl-media.com/lodging/2000000/1050000/1047500/1047474/3cee5c4d.jpg?impolicy=fcrop&w=357&h=201&p=1&q=medium) ### Ocean Villa Inn Ocean Beach 8.2/10 Very good (1122) "Room was cute, staff helpful. Location to the beach was excellent " ![United States](https://a.travel-assets.com/egds/marks/flags/us.svg) Kenta CA $113 CA $127 total includes taxes & fees Dec 7 - Dec 8 [](https://www.expedia.ca/San-Diego-Hotels-Ocean-Villa-Inn.h1047474.Hotel-Information) ![Outdoor pool, sun loungers](https://images.trvl-media.com/lodging/2000000/1880000/1871700/1871645/9fc82331.jpg?impolicy=fcrop&w=357&h=201&p=1&q=medium) ![Exterior](https://images.trvl-media.com/lodging/2000000/1880000/1871700/1871645/2df2def5.jpg?impolicy=fcrop&w=357&h=201&p=1&q=medium) ![Exterior](https://images.trvl-media.com/lodging/2000000/1880000/1871700/1871645/f10fc62f.jpg?impolicy=fcrop&w=357&h=201&p=1&q=medium) ![Breakfast, lunch, dinner served; Californian cuisine, ocean views ](https://images.trvl-media.com/lodging/2000000/1880000/1871700/1871645/06f19e3f.jpg?impolicy=fcrop&w=357&h=201&p=1&q=medium) ### Hilton San Diego Bayfront Downtown San Diego 8.6/10 Excellent (1838) "Beautiful hotel, good bar, great staff and right on the bay and close to downtown and not to far away from local beaches. " ![United States](https://a.travel-assets.com/egds/marks/flags/us.svg) Daniel CA $122 CA $209 total includes taxes & fees Dec 22 - Dec 23 [](https://www.expedia.ca/San-Diego-Hotels-Hilton-San-Diego-Bayfront.h1871645.Hotel-Information) ![Meeting facility](https://images.trvl-media.com/lodging/1000000/30000/27600/27516/1b87fc03.jpg?impolicy=fcrop&w=357&h=201&p=1&q=medium) ![Hospitality Suite, 1 King Bed, Bay View | Living room](https://images.trvl-media.com/lodging/1000000/30000/27600/27516/d02824a2.jpg?impolicy=fcrop&w=357&h=201&p=1&q=medium) ![Beach nearby, white sand](https://images.trvl-media.com/lodging/1000000/30000/27600/27516/31f9c777.jpg?impolicy=fcrop&w=357&h=201&p=1&q=medium) ![Lobby sitting area](https://images.trvl-media.com/lodging/1000000/30000/27600/27516/2ba9fb5c.jpg?impolicy=fcrop&w=357&h=201&p=1&q=medium) ### The Westin San Diego Bayview Downtown San Diego 8.6/10 Excellent (1043) "Great room in a very convenient location" ![Canada](https://a.travel-assets.com/egds/marks/flags/ca.svg) Kristjan CA $166 CA $233 total includes taxes & fees Dec 19 - Dec 20 [](https://www.expedia.ca/San-Diego-Hotels-The-Westin-San-Diego-Downtown.h27516.Hotel-Information) ![Rooftop terrace](https://images.trvl-media.com/lodging/89000000/88400000/88398500/88398416/4480f6ef.jpg?impolicy=fcrop&w=357&h=201&p=1&q=medium) ![Lobby](https://images.trvl-media.com/lodging/89000000/88400000/88398500/88398416/dd3cca67.jpg?impolicy=fcrop&w=357&h=201&p=1&q=medium) ![Lobby sitting area](https://images.trvl-media.com/lodging/89000000/88400000/88398500/88398416/881441d5.jpg?impolicy=fcrop&w=357&h=201&p=1&q=medium) ![Lobby sitting area](https://images.trvl-media.com/lodging/89000000/88400000/88398500/88398416/a314a493.jpg?impolicy=fcrop&w=357&h=201&p=1&q=medium) ### Palihotel San Diego Gaslamp Quarter Downtown San Diego 8.6/10 Excellent (2073) "Room was spotless and location great. " ![United States](https://a.travel-assets.com/egds/marks/flags/us.svg) James CA $147 CA $170 total includes taxes & fees Dec 12 - Dec 13 [](https://www.expedia.ca/San-Diego-Hotels-Palihotel-San-Diego.h88398416.Hotel-Information) ![Premium bedding, pillowtop beds, desk, laptop workspace](https://images.trvl-media.com/lodging/12000000/11490000/11486100/11486063/c31e05e6.jpg?impolicy=fcrop&w=357&h=201&p=1&q=medium) ![Hallway](https://images.trvl-media.com/lodging/12000000/11490000/11486100/11486063/ec632047.jpg?impolicy=fcrop&w=357&h=201&p=1&q=medium) ![Reception](https://images.trvl-media.com/lodging/12000000/11490000/11486100/11486063/1fbe17de.jpg?impolicy=fcrop&w=357&h=201&p=1&q=medium) ![Reception](https://images.trvl-media.com/lodging/12000000/11490000/11486100/11486063/89fdb8c4.jpg?impolicy=fcrop&w=357&h=201&p=1&q=medium) ### Staypineapple, Hotel Z, Gaslamp San Diego Downtown San Diego 9.4/10 Exceptional (1001) "The room was immaculate, the staff were helpful and friendly and our stay was so wonderful. " ![United States](https://a.travel-assets.com/egds/marks/flags/us.svg) Samantha Erin CA $146 CA $209 total includes taxes & fees Dec 8 - Dec 9 [](https://www.expedia.ca/San-Diego-Hotels-Staypineapple.h11486063.Hotel-Information) ![Marina](https://images.trvl-media.com/lodging/1000000/60000/57300/57254/80f275da.jpg?impolicy=fcrop&w=357&h=201&p=1&q=medium) ![Aerial view](https://images.trvl-media.com/lodging/1000000/60000/57300/57254/42d1a51f.jpg?impolicy=fcrop&w=357&h=201&p=1&q=medium) ![Deluxe Room, 2 Queen Beds, Harbour View](https://images.trvl-media.com/lodging/1000000/60000/57300/57254/f8a54f53.jpg?impolicy=fcrop&w=357&h=201&p=1&q=medium) ![Aerial view](https://images.trvl-media.com/lodging/1000000/60000/57300/57254/ecc06b6b.jpg?impolicy=fcrop&w=357&h=201&p=1&q=medium) ### Sea Harbor Hotel Point Loma 8.6/10 Excellent (1024) "Good hotel " ![United States](https://a.travel-assets.com/egds/marks/flags/us.svg) Diana CA $130 CA $147 total includes taxes & fees Dec 7 - Dec 8 [](https://www.expedia.ca/San-Diego-Hotels-Sea-Harbor-Hotel.h57254.Hotel-Information) ![Exterior](https://images.trvl-media.com/lodging/1000000/20000/12100/12073/0b3061e9.jpg?impolicy=fcrop&w=357&h=201&p=1&q=medium) ![Hypo-allergenic bedding, in-room safe, desk, iron/ironing board](https://images.trvl-media.com/lodging/1000000/20000/12100/12073/65055fd7.jpg?impolicy=fcrop&w=357&h=201&p=1&q=medium) ![Exterior](https://images.trvl-media.com/lodging/1000000/20000/12100/12073/3285daa5.jpg?impolicy=fcrop&w=357&h=201&p=1&q=medium) ![Exterior](https://images.trvl-media.com/lodging/1000000/20000/12100/12073/41a32bda.jpg?impolicy=fcrop&w=357&h=201&p=1&q=medium) ### Manchester Grand Hyatt San Diego Downtown San Diego 9.0/10 Wonderful (2866) "Great view and renovated room. Close to everything!" ![United States](https://a.travel-assets.com/egds/marks/flags/us.svg) Josephine CA $224 CA $336 total includes taxes & fees Dec 16 - Dec 17 [](https://www.expedia.ca/San-Diego-Hotels-Manchester-Grand-Hyatt-San-Diego.h12073.Hotel-Information) ![Balcony view](https://images.trvl-media.com/lodging/2000000/1140000/1130200/1130187/94fc9a71.jpg?impolicy=fcrop&w=357&h=201&p=1&q=medium) ![Deluxe Queen Studio Island Suite Garden | Private kitchen](https://images.trvl-media.com/lodging/2000000/1140000/1130200/1130187/009103e3.jpg?impolicy=fcrop&w=357&h=201&p=1&q=medium) ![Deluxe One Bedroom Queen Suite Oceanview | Living area](https://images.trvl-media.com/lodging/2000000/1140000/1130200/1130187/cc166255.jpg?impolicy=fcrop&w=357&h=201&p=1&q=medium) ![Porch](https://images.trvl-media.com/lodging/2000000/1140000/1130200/1130187/8fd8f477.jpg?impolicy=fcrop&w=357&h=201&p=1&q=medium) ### Los Bungalows Imperial Beach 8.2/10 Very good (503) "View and service were great. " ![United States](https://a.travel-assets.com/egds/marks/flags/us.svg) Ana [](https://www.expedia.ca/Imperial-Beach-Hotels-Sand-Castle-Inn.h1130187.Hotel-Information) ![Room, 1 King Bed with Sofa bed, Marina View | View from room](https://images.trvl-media.com/lodging/1000000/20000/11200/11109/w4000h2662x0y0-91d299a1.jpg?impolicy=fcrop&w=357&h=201&p=1&q=medium) ![Exterior](https://images.trvl-media.com/lodging/1000000/20000/11200/11109/086855c2.jpg?impolicy=fcrop&w=357&h=201&p=1&q=medium) ![5 restaurants, breakfast, lunch, dinner served; Mexican cuisine](https://images.trvl-media.com/lodging/1000000/20000/11200/11109/b3296075.jpg?impolicy=fcrop&w=357&h=201&p=1&q=medium) ![Meeting facility](https://images.trvl-media.com/lodging/1000000/20000/11200/11109/1e020b70.jpg?impolicy=fcrop&w=357&h=201&p=1&q=medium) ### Sheraton San Diego Resort Harbor Island 8.2/10 Very good (3159) "This was a great stay for a small vacation." ![United States](https://a.travel-assets.com/egds/marks/flags/us.svg) George Edmond Junior CA $131 CA $201 total includes taxes & fees Dec 27 - Dec 28 [](https://www.expedia.ca/San-Diego-Hotels-Sheraton-San-Diego-Hotel-And-Marina.h11109.Hotel-Information) Lowest nightly price found within the past 24 hours based on a 1 night stay for 2 adults. Prices and availability subject to change. Additional terms may apply. [View all properties](https://expedia.ca/Hotel-Search?startDate=2025-12-17&endDate=2025-12-18®ionId=553248625809641010&adults=2&amenities=PETS&sort=RECOMMENDED&openPlayBack=true) ## Top Otay Mesa West Hotel Reviews ![Sheraton Mission Valley San Diego Hotel](https://images.trvl-media.com/lodging/1000000/20000/11800/11725/f387ad25_y.jpg) ### Sheraton Mission Valley San Diego Hotel 10/10 Excellent "Clean hotel and friendly staff. We checked in with Eric who was nice and helpful made us feel welcomed " [](https://expedia.ca/San-Diego-Hotels-Sheraton-Mission-Valley-San-Diego-Hotel.h11725.Hotel-Information) ![Manchester Grand Hyatt San Diego](https://images.trvl-media.com/lodging/1000000/20000/12100/12073/91e2517e_y.jpg) ### Manchester Grand Hyatt San Diego 10/10 Excellent "Great view and renovated room. Close to everything!" [](https://expedia.ca/San-Diego-Hotels-Manchester-Grand-Hyatt-San-Diego.h12073.Hotel-Information) ![The Dana on Mission Bay](https://images.trvl-media.com/lodging/1000000/50000/41000/40953/08585098_y.jpg) ### The Dana on Mission Bay 10/10 Excellent "Staff was great, room was spotless, and map was easy to follow." [](https://expedia.ca/San-Diego-Hotels-The-Dana-On-Mission-Bay.h40953.Hotel-Information) ![Wyndham San Diego Bayside](https://images.trvl-media.com/lodging/1000000/20000/11200/11177/c44ff51d_y.jpg) ### Wyndham San Diego Bayside 10/10 Excellent "The staff was so friendly and made our stay a wonderful one. We will be back next time we are in San Diego!" [](https://expedia.ca/San-Diego-Hotels-Wyndham-San-Diego-Bayside.h11177.Hotel-Information) ![Best Western Plus Marina Gateway Hotel](https://images.trvl-media.com/lodging/3000000/2820000/2816700/2816688/f3777dfe_y.jpg) ### Best Western Plus Marina Gateway Hotel 10/10 Excellent "Best hotel for this amount" [](https://expedia.ca/National-City-Hotels-Best-Western-Plus-Marina-Gateway-Hotel.h2816688.Hotel-Information) ![Sheraton San Diego Resort](https://images.trvl-media.com/lodging/1000000/20000/11200/11109/w4000h2662x0y0-91d299a1_y.jpg) ### Sheraton San Diego Resort 10/10 Excellent "Driver was polite and efficient" [](https://expedia.ca/San-Diego-Hotels-Sheraton-San-Diego-Hotel-And-Marina.h11109.Hotel-Information) ![Hilton San Diego Mission Valley](https://images.trvl-media.com/lodging/1000000/20000/16100/16019/w5586h3835x5y5-2b129a15_y.jpg) ### Hilton San Diego Mission Valley 10/10 Excellent "Room was excellent, clean and friendly staff at all times of the day" [](https://expedia.ca/San-Diego-Hotels-Hilton-San-Diego-Mission-Valley.h16019.Hotel-Information) ![Wyndham Garden San Diego Near SeaWorld](https://images.trvl-media.com/lodging/1000000/50000/41000/40962/76b78879_y.jpg) ### Wyndham Garden San Diego Near SeaWorld 10/10 Excellent "Clean rooms and friendly staff." [](https://expedia.ca/San-Diego-Hotels-Wyndham-Garden-San-Diego-Near-SeaWorld.h40962.Hotel-Information) ## Frequently asked questions ### What is there to see and do with your pet in Otay Mesa West? > Known for its beautiful sunsets and cathedral, Otay Mesa West has lots to offer visitors. During your visit, enjoy checking out San Diego Convention Center and San Diego Zoo. When you're in the area, make time for a stop at top attractions like San Ysidro Border Crossing and Petco Park. ## Explore a world of travel with Expedia - Lodging - More ways to book - [Beach Hotel Hotels in Camp Pendleton Marine Corps Base](https://www.expedia.ca/Camp-Pendleton-Marine-Corps-Base-Hotels-Beach-Hotel.0-0-d6068523-tBeachHotel.Travel-Guide-Filter-Hotels) - [Hotels with an Indoor Pool in Camp Pendleton Marine Corps Base](https://www.expedia.ca/Camp-Pendleton-Marine-Corps-Base-Hotels-Hotels-With-Indoor-Pool.0-0-d6068523-tHotelswithIndoorPool.Travel-Guide-Filter-Hotels) - [Oceanfront Hotels in Camp Pendleton Marine Corps Base](https://www.expedia.ca/Camp-Pendleton-Marine-Corps-Base-Hotels-Oceanfront-Hotels.0-0-d6068523-tOceanfrontHotels.Travel-Guide-Filter-Hotels) - [Ski Hotels in Camp Pendleton Marine Corps Base](https://www.expedia.ca/Camp-Pendleton-Marine-Corps-Base-Hotels-Ski-Hotel.0-0-d6068523-tSkiHotel.Travel-Guide-Filter-Hotels) - [Hotels & Resorts for Couples in Carlsbad](https://www.expedia.ca/Carlsbad-Hotels-Couples-Resorts-Hotels.0-0-d6056550-tCouplesResortsHotels.Travel-Guide-Filter-Hotels) - 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