Title: Hotels by Noble House in Otay Mesa West from CA $413 | Expedia.ca [Otay Mesa West Travel Guide](https://expedia.ca/San-Diego-Otay-Mesa-West.dx553248625809641010)[Vacation Rentals in San Diego](https://expedia.ca/San-Diego-Vacation-Rentals.d3073.Travel-Guide-VacationRentals)[Flights to San Diego](https://expedia.ca/Cheap-Flights-To-San-Diego.d3073.Travel-Guide-Flights)[Things to do in San Diego](https://expedia.ca/Things-To-Do-In-San-Diego.d3073.Travel-Guide-Activities)[Otay Mesa West Car Rentals](https://expedia.ca/Car-Rentals-In-Otay-Mesa-West.d553248625809641010.Car-Rental-Guide)[Otay Mesa West Vacations](https://expedia.ca/Otay-Mesa-West.d553248625809641010.Destination-Travel-Guides) ![](https://mediaim.expedia.com/destination/2/c82ea711c1af69b78661e7f0e8d60f0e.jpg?impolicy=fcrop&w=1200&h=500&q=medium) Photo by Leonardo De Leon # Find Hotels by Noble House in Otay Mesa West from CA $413 ![calendar shield illustration](https://a.travel-assets.com/travel-assets-manager/pictogram-bex/light__calendar_shield.svg) ### Change your mind Book hotels with free cancellation ![deals illustration](https://a.travel-assets.com/travel-assets-manager/pictogram-bex/light__deals.svg) ### Treat yourself Sign in to save 10% or more on thousands of hotels [Sign in](https://www.expedia.ca/login) ![bed illustration](https://a.travel-assets.com/travel-assets-manager/pictogram-bex/light__bed.svg) ### Be picky Search almost a million properties worldwide ## Check prices for these dates Tonight [Oct 1 - Oct 2](https://www.expedia.ca/Hotel-Search?regionId=553248625809641010&startDate=2025-10-01&endDate=2025-10-02&adults=2&rfrr=TG.LP.CheckPrices.Hotel&openPlayBack=true) Tomorrow [Oct 2 - Oct 3](https://www.expedia.ca/Hotel-Search?regionId=553248625809641010&startDate=2025-10-02&endDate=2025-10-03&adults=2&rfrr=TG.LP.CheckPrices.Hotel&openPlayBack=true) This weekend [Oct 3 - Oct 5](https://www.expedia.ca/Hotel-Search?regionId=553248625809641010&startDate=2025-10-03&endDate=2025-10-05&adults=2&rfrr=TG.LP.CheckPrices.Hotel&openPlayBack=true) Next weekend [Oct 10 - Oct 12](https://www.expedia.ca/Hotel-Search?regionId=553248625809641010&startDate=2025-10-10&endDate=2025-10-12&adults=2&rfrr=TG.LP.CheckPrices.Hotel&openPlayBack=true) ## Top Otay Mesa West Noble House Hotels ![Outdoor pool, open 9:00 AM to 9:00 PM, cabanas (surcharge)](https://images.trvl-media.com/lodging/1000000/30000/25600/25598/bbcdbd6d.jpg?impolicy=fcrop&w=357&h=201&p=1&q=medium) ![2 restaurants, breakfast, lunch, dinner served; American cuisine](https://images.trvl-media.com/lodging/1000000/30000/25600/25598/de48676b.jpg?impolicy=fcrop&w=357&h=201&p=1&q=medium) ![Premium bedding, down comforters, pillowtop beds, in-room safe](https://images.trvl-media.com/lodging/1000000/30000/25600/25598/c2cecb91.jpg?impolicy=fcrop&w=357&h=201&p=1&q=medium) ![Outdoor wedding area](https://images.trvl-media.com/lodging/1000000/30000/25600/25598/eae398b2.jpg?impolicy=fcrop&w=357&h=201&p=1&q=medium) ### San Diego Mission Bay Resort San Diego 8.4/10 Very good (1287) "Beautiful area" CA $305 CA $413 total includes taxes & fees Oct 26 - Oct 27 [](https://www.expedia.ca/San-Diego-Hotels-San-Diego-Mission-Bay-Resort.h25598.Hotel-Information) ![2 outdoor pools, open 6:00 AM to 10:00 PM, cabanas (surcharge)](https://images.trvl-media.com/lodging/1000000/30000/28200/28118/984a9e79.jpg?impolicy=fcrop&w=357&h=201&p=1&q=medium) ![Outdoor wedding area](https://images.trvl-media.com/lodging/1000000/30000/28200/28118/b8e975c0.jpg?impolicy=fcrop&w=357&h=201&p=1&q=medium) ![View from property](https://images.trvl-media.com/lodging/1000000/30000/28200/28118/dce3e70b.jpg?impolicy=fcrop&w=357&h=201&p=1&q=medium) ![Water view](https://images.trvl-media.com/lodging/1000000/30000/28200/28118/8bb52ffd.jpg?impolicy=fcrop&w=357&h=201&p=1&q=medium) ### Kona Kai San Diego Point Loma 8.2/10 Very good (1000) "We enjoyed the beautiful views of the Marina and sitting at the Fire pit in the evening. " CA $291 CA $418 total includes taxes & fees Oct 5 - Oct 6 [](https://www.expedia.ca/San-Diego-Hotels-Kona-Kai-San-Diego.h28118.Hotel-Information) Lowest nightly price found within the past 24 hours based on a 1 night stay for 2 adults. Prices and availability subject to change. Additional terms may apply. [View all properties](https://expedia.ca/Hotel-Search?startDate=2025-10-15&endDate=2025-10-16®ionId=553248625809641010&adults=2&sort=RECOMMENDED&openPlayBack=true) ![](https://a.travel-assets.com/pricing-claim/sparkle_dark.svg) Save an average of 15% on thousands of hotels when you're signed in [Sign in](https://expedia.ca/user/signin?ckoflag=0&uurl=e3id%3Dredr%26rurl%3D%2FOtay-Mesa-West-San-Diego-Hotels-Noble-House.0-n553248625809641010-0--bNobleHouse.Travel-Guide-Filter-Hotels)[Sign up, it's free](https://expedia.ca/signup?enable_registration=true&+=&uurl=e3id%3Dredr%26rurl%3D%2FOtay-Mesa-West-San-Diego-Hotels-Noble-House.0-n553248625809641010-0--bNobleHouse.Travel-Guide-Filter-Hotels) ## Top Otay Mesa West Hotel Reviews ![Hard Rock Hotel San Diego](//images.trvl-media.com/lodging/2000000/1740000/1731600/1731557/fbbdfc57_y.jpg) ### Hard Rock Hotel San Diego 10/10 Excellent "Clean room" [](https://expedia.ca/San-Diego-Hotels-Hard-Rock-Hotel-San-Diego.h1731557.Hotel-Information) ![Best Western Plus Marina Gateway Hotel](//images.trvl-media.com/lodging/3000000/2820000/2816700/2816688/f3777dfe_y.jpg) ### Best Western Plus Marina Gateway Hotel 10/10 Excellent "Thanks " [](https://expedia.ca/National-City-Hotels-Best-Western-Plus-Marina-Gateway-Hotel.h2816688.Hotel-Information) ![Wyndham San Diego Bayside](//images.trvl-media.com/lodging/1000000/20000/11200/11177/c44ff51d_y.jpg) ### Wyndham San Diego Bayside 10/10 Excellent "Hotel is in a great location right near airport and trolley. Has an airport shuttle, pool, 3 restaurants on site and a few access the street. Best of all the staff and management are really friendly and professional. " [](https://expedia.ca/San-Diego-Hotels-Wyndham-San-Diego-Bayside.h11177.Hotel-Information) ![The Sofia Hotel](//images.trvl-media.com/lodging/2000000/1580000/1573900/1573807/ba6cea84_y.jpg) ### The Sofia Hotel 10/10 Excellent "Clean room, friendly staff " [](https://expedia.ca/San-Diego-Hotels-The-Sofia-Hotel.h1573807.Hotel-Information) ![Sheraton San Diego Resort](//images.trvl-media.com/lodging/1000000/20000/11200/11109/w4000h2662x0y0-91d299a1_y.jpg) ### Sheraton San Diego Resort 10/10 Excellent "Had a comfortable stay" [](https://expedia.ca/San-Diego-Hotels-Sheraton-San-Diego-Hotel-And-Marina.h11109.Hotel-Information) ![The Dana on Mission Bay](//images.trvl-media.com/lodging/1000000/50000/41000/40953/08585098_y.jpg) ### The Dana on Mission Bay 10/10 Excellent "We stayed for 9 nights and had an awesome time! Staff was friendly and accommodating. " [](https://expedia.ca/San-Diego-Hotels-The-Dana-On-Mission-Bay.h40953.Hotel-Information) ![Hotel del Coronado, Curio Collection by Hilton](//images.trvl-media.com/lodging/1000000/10000/7500/7496/20fe4d95_y.jpg) ### Hotel del Coronado, Curio Collection by Hilton 10/10 Excellent "Great ocean view located right on wide beach. Hotel is awesome." [](https://expedia.ca/Coronado-Hotels-Hotel-Del-Coronado.h7496.Hotel-Information) ![Manchester Grand Hyatt San Diego](//images.trvl-media.com/lodging/1000000/20000/12100/12073/w3840h2092x0y3-447c77a4_y.jpg) ### Manchester Grand Hyatt San Diego 10/10 Excellent "The Manchester Grand Hyatt is our go to hotel in San Diego due to its convenient location by the Seaport Village and many restaurants and shops. We have stayed there several times and always enjoy the scenic views from our room and the hospitality of the hotel staff. The breakfast buffet has a large variety of offerings including an omelette station. The MarketOne Cafe downstairs has many items including delicious pastries and other food and drink items. It is always a great experience to stay at the Manchester Grand Hyatt in San Diego." [](https://expedia.ca/San-Diego-Hotels-Manchester-Grand-Hyatt-San-Diego.h12073.Hotel-Information) ![Legacy Resort Hotel & Spa](//images.trvl-media.com/lodging/42000000/41510000/41504800/41504735/0bbd67f4_y.jpg) ### Legacy Resort Hotel & Spa 10/10 Excellent "Staff were extremely helpful and kind. Room was so clean and quiet. These were the most comfortable hotel beds we have ever slept on. It is a great location for dining and shopping and just about everything else in San Diego, except the beach. Great experience!" [](https://expedia.ca/San-Diego-Hotels-Legacy-Resort-Hotel-Spa.h41504735.Hotel-Information) ## Find out more about Otay Mesa West ## Otay Mesa West Hotels Guide Expedia.ca offers a selection of 6709 hotels in Otay Mesa West. You are sure to find cheap deals and discount rates among them with our Best Price Guarantee. No matter what type of hotel strikes your fancy, we will let you search for your preferred one to accommodate your travel needs. Expedia.ca will not only save you time, but also money when booking your stay at a hotel in Otay Mesa West. Making reservations so you can stay within your budget is easy with us. Expedia.ca even provides you with a map so you may find hotels in the Otay Mesa West neighborhood you prefer. Go ahead. 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[Luxury Car Rentals in South San Diego](https://www.expedia.ca/Luxury-Car-Rentals-In-South-San-Diego.d553248632063518562-tLuxury.Car-Rental-Guide-Class) - [Midway Car Rental Rental Cars in South San Diego](https://www.expedia.ca/Midway-Car-Rental-Car-Rentals-In-South-San-Diego.d553248632063518562-c27.Car-Rental-Guide-Suppliers) - [Pickup Car Rentals in South San Diego](https://www.expedia.ca/Pickup-Car-Rentals-In-South-San-Diego.d553248632063518562-tPickup.Car-Rental-Guide-Class) - [Priceless Car Rental Rental Cars in South San Diego](https://www.expedia.ca/Priceless-Car-Rental-Car-Rentals-In-South-San-Diego.d553248632063518562-c1060.Car-Rental-Guide-Suppliers) - [Routes Rental Cars in South San Diego](https://www.expedia.ca/Routes-Car-Rentals-In-South-San-Diego.d553248632063518562-c1101.Car-Rental-Guide-Suppliers) - [Things to do in San Ysidro](https://www.expedia.ca/Things-To-Do-In-San-Ysidro.d8380.Travel-Guide-Activities) - [Book Hotels in Otay Mesa West on Expedia.com](https://www.expedia.com/Otay-Mesa-West-San-Diego-Hotels-Noble-House.0-n553248625809641010-0--bNobleHouse.Travel-Guide-Filter-Hotels)