Title: Book the Best ROMANTIC Hotels in Otay Mesa, San Diego from CA $124 - Otay Mesa Romantic Getaways | Expedia.ca [Vacation Rentals in San Diego](https://expedia.ca/San-Diego-Vacation-Rentals.d3073.Travel-Guide-VacationRentals)[Flights to San Diego](https://expedia.ca/Cheap-Flights-To-San-Diego.d3073.Travel-Guide-Flights)[Things to do in San Diego](https://expedia.ca/Things-To-Do-In-San-Diego.d3073.Travel-Guide-Activities)[Otay Mesa Car Rentals](https://expedia.ca/Car-Rentals-In-Otay-Mesa.d6263723.Car-Rental-Guide)[Otay Mesa Vacations](https://expedia.ca/Otay-Mesa.d6263723.Destination-Travel-Guides) ![Default HTG hotel image](https://media.expedia.com/media/content/shared/images/travelguides/sem-hotels-tablet.jpg?impolicy=fcrop&w=1200&h=500&q=medium) # Find Romantic Hotels in Otay Mesa, San Diego from CA $124 ![](https://a.travel-assets.com/travel-assets-manager/pictogram-bex/light__calendar_shield.svg) ### Change your mind Book hotels with free cancellation ![](https://a.travel-assets.com/travel-assets-manager/pictogram-bex/light__deals.svg) ### Treat yourself Sign in to save 10% or more on thousands of hotels [Sign in](https://www.expedia.ca/login) ![](https://a.travel-assets.com/travel-assets-manager/pictogram-bex/light__bed.svg) ### Be picky Search almost a million properties worldwide ## Check availability on Otay Mesa Romantic Hotels Tonight [Oct 20 - Oct 21](https://www.expedia.ca/Hotel-Search?regionId=6263723&startDate=2025-10-20&endDate=2025-10-21&adults=2&rfrr=TG.LP.CheckPrices.Hotel&openPlayBack=true&travelerType=romantic) Tomorrow [Oct 21 - Oct 22](https://www.expedia.ca/Hotel-Search?regionId=6263723&startDate=2025-10-21&endDate=2025-10-22&adults=2&rfrr=TG.LP.CheckPrices.Hotel&openPlayBack=true&travelerType=romantic) This weekend [Oct 24 - Oct 26](https://www.expedia.ca/Hotel-Search?regionId=6263723&startDate=2025-10-24&endDate=2025-10-26&adults=2&rfrr=TG.LP.CheckPrices.Hotel&openPlayBack=true&travelerType=romantic) Next weekend [Oct 31 - Nov 2](https://www.expedia.ca/Hotel-Search?regionId=6263723&startDate=2025-10-31&endDate=2025-11-02&adults=2&rfrr=TG.LP.CheckPrices.Hotel&openPlayBack=true&travelerType=romantic) ## Top Otay Mesa Romantic Hotels ![Outdoor pool](https://images.trvl-media.com/lodging/1000000/580000/571600/571545/f294be65.jpg?impolicy=fcrop&w=357&h=201&p=1&q=medium) ![Point of interest](https://images.trvl-media.com/lodging/1000000/580000/571600/571545/d3b44b8b.jpg?impolicy=fcrop&w=357&h=201&p=1&q=medium) ![Meeting facility](https://images.trvl-media.com/lodging/1000000/580000/571600/571545/1b688cf4.jpg?impolicy=fcrop&w=357&h=201&p=1&q=medium) ![Property amenity](https://images.trvl-media.com/lodging/1000000/580000/571600/571545/48aa6044.jpg?impolicy=fcrop&w=357&h=201&p=1&q=medium) ### Crowne Plaza San Diego - Mission Valley by IHG Mission Valley 7.8/10 Good (1045) "Good value Nice place to stay " ![United States](https://a.travel-assets.com/egds/marks/flags/us.svg) John CA $143 CA $165 total includes taxes & fees Oct 26 - Oct 27 [](https://www.expedia.ca/San-Diego-Hotels-Crowne-Plaza-San-Diego-Mission-Valley.h571545.Hotel-Information) ![3 outdoor pools, cabanas (surcharge), pool umbrellas](https://images.trvl-media.com/lodging/34000000/33670000/33661500/33661441/1f4c359a.jpg?impolicy=fcrop&w=357&h=201&p=1&q=medium) ![7 restaurants, breakfast served](https://images.trvl-media.com/lodging/34000000/33670000/33661500/33661441/250333ae.jpg?impolicy=fcrop&w=357&h=201&p=1&q=medium) ![1 bedroom, hypo-allergenic bedding, down comforters, pillowtop beds](https://images.trvl-media.com/lodging/34000000/33670000/33661500/33661441/8995625e.jpg?impolicy=fcrop&w=357&h=201&p=1&q=medium) ![7 restaurants, breakfast served](https://images.trvl-media.com/lodging/34000000/33670000/33661500/33661441/7910f1d4.jpg?impolicy=fcrop&w=357&h=201&p=1&q=medium) ### Sycuan Casino Resort El Cajon 9.2/10 Wonderful (1582) "Great resort!" ![United States](https://a.travel-assets.com/egds/marks/flags/us.svg) Vicky CA $126 CA $156 total includes taxes & fees Nov 19 - Nov 20 [](https://www.expedia.ca/El-Cajon-Hotels-Sycuan-Casino-Resort.h33661441.Hotel-Information) ![Reception](https://images.trvl-media.com/lodging/1000000/20000/17000/16910/a5f26080.jpg?impolicy=fcrop&w=357&h=201&p=1&q=medium) ![Reception](https://images.trvl-media.com/lodging/1000000/20000/17000/16910/f52073d5.jpg?impolicy=fcrop&w=357&h=201&p=1&q=medium) ![Lobby sitting area](https://images.trvl-media.com/lodging/1000000/20000/17000/16910/8104aff0.jpg?impolicy=fcrop&w=357&h=201&p=1&q=medium) ![Standard Room, 2 Queen Beds](https://images.trvl-media.com/lodging/1000000/20000/17000/16910/c007c44b.jpg?impolicy=fcrop&w=357&h=201&p=1&q=medium) ### Kings Inn San Diego Mission Valley 8.8/10 Excellent (3489) "Great place to stay!" ![United States](https://a.travel-assets.com/egds/marks/flags/us.svg) Melissa CA $108 CA $124 total includes taxes & fees Oct 21 - Oct 22 [](https://www.expedia.ca/San-Diego-Hotels-Kings-Inn-San-Diego-Seaworld-Zoo.h16910.Hotel-Information) ![Exterior](https://images.trvl-media.com/lodging/1000000/10000/900/858/c5325c92.jpg?impolicy=fcrop&w=357&h=201&p=1&q=medium) ![Front of property](https://images.trvl-media.com/lodging/1000000/10000/900/858/c6795882.jpg?impolicy=fcrop&w=357&h=201&p=1&q=medium) ![Down comforters, pillowtop beds, in-room safe, desk](https://images.trvl-media.com/lodging/1000000/10000/900/858/93b051f7.jpg?impolicy=fcrop&w=357&h=201&p=1&q=medium) ![Penthouse](https://images.trvl-media.com/lodging/1000000/10000/900/858/36c2b78d.jpg?impolicy=fcrop&w=357&h=201&p=1&q=medium) ### Hyatt Regency Mission Bay Spa and Marina Mission Bay 8.4/10 Very good (1550) "Clean rooms great view amazing pool and we loved the breakfast " ![United States](https://a.travel-assets.com/egds/marks/flags/us.svg) ad CA $237 CA $347 total includes taxes & fees Nov 1 - Nov 2 [](https://www.expedia.ca/San-Diego-Hotels-Hyatt-Regency-Mission-Bay-Spa-And-Marina.h858.Hotel-Information) ![Terrace/patio](https://images.trvl-media.com/lodging/1000000/20000/11200/11177/c44ff51d.jpg?impolicy=fcrop&w=357&h=201&p=1&q=medium) ![City view](https://images.trvl-media.com/lodging/1000000/20000/11200/11177/88f9cd22.jpg?impolicy=fcrop&w=357&h=201&p=1&q=medium) ![Lobby](https://images.trvl-media.com/lodging/1000000/20000/11200/11177/7f3bc7ed.jpg?impolicy=fcrop&w=357&h=201&p=1&q=medium) ![32-inch LCD TV with digital channels, TV](https://images.trvl-media.com/lodging/1000000/20000/11200/11177/d5ea2f3b.jpg?impolicy=fcrop&w=357&h=201&p=1&q=medium) ### Wyndham San Diego Bayside Downtown San Diego 8.4/10 Very good (6000) "Enjoyed our stay very much." ![United States](https://a.travel-assets.com/egds/marks/flags/us.svg) David CA $189 CA $260 total includes taxes & fees Oct 26 - Oct 27 [](https://www.expedia.ca/San-Diego-Hotels-Wyndham-San-Diego-Bayside.h11177.Hotel-Information) ![Outdoor pool, open 7:00 AM to 9:00 PM, cabanas (surcharge)](https://images.trvl-media.com/lodging/39000000/38080000/38077800/38077738/91a184a3.jpg?impolicy=fcrop&w=357&h=201&p=1&q=medium) ![Lobby sitting area](https://images.trvl-media.com/lodging/39000000/38080000/38077800/38077738/116e1fe0.jpg?impolicy=fcrop&w=357&h=201&p=1&q=medium) ![2 bedrooms, premium bedding, pillowtop beds, minibar](https://images.trvl-media.com/lodging/39000000/38080000/38077800/38077738/633cc48d.jpg?impolicy=fcrop&w=357&h=201&p=1&q=medium) ![Front of property](https://images.trvl-media.com/lodging/39000000/38080000/38077800/38077738/56fafd1b.jpg?impolicy=fcrop&w=357&h=201&p=1&q=medium) ### Lafayette Hotel & Club University Heights 9.4/10 Exceptional (1226) "10/10 looooove loooove this place will be coming back " ![United States](https://a.travel-assets.com/egds/marks/flags/us.svg) Moises CA $317 CA $364 total includes taxes & fees Oct 21 - Oct 22 [](https://www.expedia.ca/San-Diego-Hotels-Lafayette-Hotel.h38077738.Hotel-Information) ![Exterior](https://images.trvl-media.com/lodging/1000000/10000/2600/2514/8c022c3d.jpg?impolicy=fcrop&w=357&h=201&p=1&q=medium) ![Outdoor pool, open 7:00 AM to 10:00 PM, pool umbrellas, sun loungers](https://images.trvl-media.com/lodging/1000000/10000/2600/2514/44c79c07.jpg?impolicy=fcrop&w=357&h=201&p=1&q=medium) ![View from room](https://images.trvl-media.com/lodging/1000000/10000/2600/2514/676f55ca.jpg?impolicy=fcrop&w=357&h=201&p=1&q=medium) ![Breakfast, lunch, dinner served; American cuisine, pool views ](https://images.trvl-media.com/lodging/1000000/10000/2600/2514/1f20ac82.jpg?impolicy=fcrop&w=357&h=201&p=1&q=medium) ### Bay Club Hotel & Marina Point Loma 9.0/10 Wonderful (3037) "Great location, friendly staff, very clean accommodations and spacious rooms " ![United States](https://a.travel-assets.com/egds/marks/flags/us.svg) Brandy CA $175 CA $202 total includes taxes & fees Oct 21 - Oct 22 [](https://www.expedia.ca/San-Diego-Hotels-Bay-Club-Hotel-Marina.h2514.Hotel-Information) ![Property amenity](https://images.trvl-media.com/lodging/1000000/10000/8400/8332/21e561fb.jpg?impolicy=fcrop&w=357&h=201&p=1&q=medium) ![Bar (on property)](https://images.trvl-media.com/lodging/1000000/10000/8400/8332/d6460a60.jpg?impolicy=fcrop&w=357&h=201&p=1&q=medium) ![Terrace/patio](https://images.trvl-media.com/lodging/1000000/10000/8400/8332/4d5866ea.jpg?impolicy=fcrop&w=357&h=201&p=1&q=medium) ![Reception](https://images.trvl-media.com/lodging/1000000/10000/8400/8332/0dccf6b6.jpg?impolicy=fcrop&w=357&h=201&p=1&q=medium) ### San Diego Marriott Mission Valley Mission Valley 8.6/10 Excellent (1018) "Great location and very clean property. Restaurant was fantastic!" ![United States](https://a.travel-assets.com/egds/marks/flags/us.svg) Shawna CA $178 CA $204 total includes taxes & fees Oct 27 - Oct 28 [](https://www.expedia.ca/San-Diego-Hotels-San-Diego-Marriott-Mission-Valley.h8332.Hotel-Information) ![Exterior](https://images.trvl-media.com/lodging/1000000/30000/25900/25840/c2d82864.jpg?impolicy=fcrop&w=357&h=201&p=1&q=medium) ![Terrace/patio](https://images.trvl-media.com/lodging/1000000/30000/25900/25840/99024d06.jpg?impolicy=fcrop&w=357&h=201&p=1&q=medium) ![Cafe](https://images.trvl-media.com/lodging/1000000/30000/25900/25840/a3c5905c.jpg?impolicy=fcrop&w=357&h=201&p=1&q=medium) ![3 outdoor pools, cabanas (surcharge), pool umbrellas](https://images.trvl-media.com/lodging/1000000/30000/25900/25840/c2540b7d.jpg?impolicy=fcrop&w=357&h=201&p=1&q=medium) ### Loews Coronado Bay Resort Silver Strand 8.8/10 Excellent (1054) "Beautiful quiet hotel." ![United States](https://a.travel-assets.com/egds/marks/flags/us.svg) Lori CA $279 CA $374 total includes taxes & fees Oct 26 - Oct 27 [](https://www.expedia.ca/Coronado-Hotels-Loews-Coronado-Bay-Resort.h25840.Hotel-Information) ![Outdoor pool](https://images.trvl-media.com/lodging/1000000/40000/36200/36183/7cb5b7d9.jpg?impolicy=fcrop&w=357&h=201&p=1&q=medium) ![Property grounds](https://images.trvl-media.com/lodging/1000000/40000/36200/36183/98dcc319.jpg?impolicy=fcrop&w=357&h=201&p=1&q=medium) ![Reception](https://images.trvl-media.com/lodging/1000000/40000/36200/36183/cc6aac5f.jpg?impolicy=fcrop&w=357&h=201&p=1&q=medium) ![Sundeck](https://images.trvl-media.com/lodging/1000000/40000/36200/36183/52554aaa.jpg?impolicy=fcrop&w=357&h=201&p=1&q=medium) ### Humphreys Half Moon Inn Point Loma 9.2/10 Wonderful (2581) "Lovely place to stay" ![United States](https://a.travel-assets.com/egds/marks/flags/us.svg) Mary CA $178 CA $232 total includes taxes & fees Nov 20 - Nov 21 [](https://www.expedia.ca/San-Diego-Hotels-Humphreys-Half-Moon-Inn.h36183.Hotel-Information) Lowest nightly price found within the past 24 hours based on a 1 night stay for 2 adults. Prices and availability subject to change. Additional terms may apply. [View all properties](https://expedia.ca/Hotel-Search?startDate=2025-11-03&endDate=2025-11-04®ionId=6263723&adults=2&travelerType=romantic&sort=RECOMMENDED&openPlayBack=true) ## Top Otay Mesa Hotel Reviews ![Wyndham San Diego Bayside](//images.trvl-media.com/lodging/1000000/20000/11200/11177/c44ff51d_y.jpg) ### Wyndham San Diego Bayside 10/10 Excellent "Older property but great location. Friendly staff and lots nearby. " [](https://expedia.ca/San-Diego-Hotels-Wyndham-San-Diego-Bayside.h11177.Hotel-Information) ![Courtyard by Marriott San Diego Downtown Little Italy](//images.trvl-media.com/lodging/1000000/20000/13300/13205/0339a25b_y.jpg) ### Courtyard by Marriott San Diego Downtown Little Italy 10/10 Excellent "Amazing staff! From front desk to dinning and bar area! Safe area, walking distance to restaurants " [](https://expedia.ca/San-Diego-Hotels-The-Little-Italy-Hotel-In-Downtown-San-Diego.h13205.Hotel-Information) ![The DEXTRO Little Italy, BW Premier Collection](//images.trvl-media.com/lodging/1000000/180000/170400/170338/84efd019_y.jpg) ### The DEXTRO Little Italy, BW Premier Collection 10/10 Excellent "The only negative is you have to pay for parking daily $35 and a fee " [](https://expedia.ca/San-Diego-Hotels-Four-Points-By-Sheraton-San-Diego-Downtown-Little-Italy.h170338.Hotel-Information) ![Manchester Grand Hyatt San Diego](//images.trvl-media.com/lodging/1000000/20000/12100/12073/w3840h2092x0y3-447c77a4_y.jpg) ### Manchester Grand Hyatt San Diego 10/10 Excellent "The hotel is beautiful and conveniently located near Seaport Village, offering everything you need within walking distance. You and your family can fully enjoy your stay without having to venture far—Seaport Village and the hotel itself provide plenty to experience. The dining options are both affordable and excellent. There is truly no better hotel to choose from." [](https://expedia.ca/San-Diego-Hotels-Manchester-Grand-Hyatt-San-Diego.h12073.Hotel-Information) ![Hilton San Diego Mission Valley](//images.trvl-media.com/lodging/1000000/20000/16100/16019/w3839h2160x1y0-98566ca3_y.jpg) ### Hilton San Diego Mission Valley 10/10 Excellent "Super easy check in process, staff was extremely hospitable. My room was comfortable as well. Great job Hilton" [](https://expedia.ca/San-Diego-Hotels-Hilton-San-Diego-Mission-Valley.h16019.Hotel-Information) ![Days Inn by Wyndham San Diego Hotel Circle](//images.trvl-media.com/lodging/1000000/20000/19300/19220/3334d773_y.jpg) ### Days Inn by Wyndham San Diego Hotel Circle 10/10 Excellent "Great for the price" [](https://expedia.ca/San-Diego-Hotels-Days-Inn-By-Wyndham-San-Diego-Hotel-Circle.h19220.Hotel-Information) ![Wyndham Garden San Diego Near SeaWorld](//images.trvl-media.com/lodging/1000000/50000/41000/40962/76b78879_y.jpg) ### Wyndham Garden San Diego Near SeaWorld 10/10 Excellent "Great location. Very central. Did not love how you can hear everything outside your room " [](https://expedia.ca/San-Diego-Hotels-Wyndham-Garden-San-Diego-Near-SeaWorld.h40962.Hotel-Information) ![DoubleTree by Hilton Hotel San Diego - Mission Valley](//images.trvl-media.com/lodging/1000000/10000/400/332/8e34f752_y.jpg) ### DoubleTree by Hilton Hotel San Diego - Mission Valley 10/10 Excellent "It was a quick over night stay. Did not use any additional amenities. Always enjoy the warm cookies!" [](https://expedia.ca/San-Diego-Hotels-DoubleTree-By-Hilton-Hotel-San-Diego-Mission-Valley.h332.Hotel-Information) ![Hotel del Coronado, Curio Collection by Hilton](//images.trvl-media.com/lodging/1000000/10000/7500/7496/20fe4d95_y.jpg) ### Hotel del Coronado, Curio Collection by Hilton 10/10 Excellent "Perfect room overlooking beach. Veranda dining experience was top notch, outstanding service and excellent food " [](https://expedia.ca/Coronado-Hotels-Hotel-Del-Coronado.h7496.Hotel-Information) ## Frequently asked questions ### Searching for romantic hotels in Otay Mesa? > If you and your partner need some romantic time away, we've got just the ticket. Our guests also enjoy Otay Mesa for its shopping, restaurants, and beaches. If you want to get out and explore the larger area, you might head to San Diego Zoo, Hotel del Coronado, or Petco Park. If you're interested in staying close to a particular destination, you can sort properties by neighborhood or distance to top landmarks, so you'll be able to see everything on your list. ### What is there to do in Otay Mesa? > There's nothing better than experiencing a new destination with your sweetheart, so consider taking time to discover all there is to see and do in Otay Mesa. Couples looking for a little of everything will enjoy Otay Mesa for its shopping, restaurants, and beaches. There's plenty to see in the greater San Diego area, so you might plan to visit San Diego Zoo, Hotel del Coronado, or Petco Park. ## Explore a world of travel with Expedia - Lodging - More ways to book - [Beach Hotel Hotels in Camp Pendleton Marine Corps Base](https://www.expedia.ca/Camp-Pendleton-Marine-Corps-Base-Hotels-Beach-Hotel.0-0-d6068523-tBeachHotel.Travel-Guide-Filter-Hotels) - [Hotels with Early Check-in in Camp Pendleton Marine Corps Base](https://www.expedia.ca/Camp-Pendleton-Marine-Corps-Base-Hotels-Hotel-With-Early-Check-In.0-0-d6068523-thotelwithearlycheckin.Travel-Guide-Filter-Hotels) - [Hotels with an Indoor Pool in Camp Pendleton Marine Corps Base](https://www.expedia.ca/Camp-Pendleton-Marine-Corps-Base-Hotels-Hotels-With-Indoor-Pool.0-0-d6068523-tHotelswithIndoorPool.Travel-Guide-Filter-Hotels) - [Luxury Hotels in Camp Pendleton Marine Corps Base](https://www.expedia.ca/Camp-Pendleton-Marine-Corps-Base-Hotels-Luxury-Hotel.0-0-d6068523-tLuxuryHotel.Travel-Guide-Filter-Hotels) - 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