Title: Book the Best PET FRIENDLY Hotels in Otay Mesa, San Diego from CA $94 - Otay Mesa Dog-Friendly Hotels | Expedia.ca [Vacation Rentals in San Diego](https://expedia.ca/San-Diego-Vacation-Rentals.d3073.Travel-Guide-VacationRentals)[Flights to San Diego](https://expedia.ca/Cheap-Flights-To-San-Diego.d3073.Travel-Guide-Flights)[Things to do in San Diego](https://expedia.ca/Things-To-Do-In-San-Diego.d3073.Travel-Guide-Activities)[Otay Mesa Car Rentals](https://expedia.ca/Car-Rentals-In-Otay-Mesa.d6263723.Car-Rental-Guide)[Otay Mesa Vacations](https://expedia.ca/Otay-Mesa.d6263723.Destination-Travel-Guides) ![Default HTG hotel image](https://media.expedia.com/media/content/shared/images/travelguides/sem-hotels-tablet.jpg?impolicy=fcrop&w=1200&h=500&q=medium) # Find Pet-friendly Hotels in Otay Mesa, San Diego from CA $94 ![](https://a.travel-assets.com/travel-assets-manager/pictogram-bex/light__calendar_shield.svg) ### Change your mind Book hotels with free cancellation ![](https://a.travel-assets.com/travel-assets-manager/pictogram-bex/light__deals.svg) ### Treat yourself Sign in to save 10% or more on thousands of hotels [Sign in](https://www.expedia.ca/login) ![](https://a.travel-assets.com/travel-assets-manager/pictogram-bex/light__bed.svg) ### Be picky Search almost a million properties worldwide ## Check availability on Otay Mesa Pet-friendly Hotels Tonight [Oct 29 - Oct 30](https://www.expedia.ca/Hotel-Search?regionId=6263723&startDate=2025-10-29&endDate=2025-10-30&adults=2&amenities=PETS&rfrr=TG.LP.CheckPrices.Hotel&openPlayBack=true) Tomorrow [Oct 30 - Oct 31](https://www.expedia.ca/Hotel-Search?regionId=6263723&startDate=2025-10-30&endDate=2025-10-31&adults=2&amenities=PETS&rfrr=TG.LP.CheckPrices.Hotel&openPlayBack=true) This weekend [Oct 31 - Nov 2](https://www.expedia.ca/Hotel-Search?regionId=6263723&startDate=2025-10-31&endDate=2025-11-02&adults=2&amenities=PETS&rfrr=TG.LP.CheckPrices.Hotel&openPlayBack=true) Next weekend [Nov 7 - Nov 9](https://www.expedia.ca/Hotel-Search?regionId=6263723&startDate=2025-11-07&endDate=2025-11-09&adults=2&amenities=PETS&rfrr=TG.LP.CheckPrices.Hotel&openPlayBack=true) ## Top Otay Mesa Pet-friendly Hotels ![Premium bedding, pillowtop beds, desk, laptop workspace](https://images.trvl-media.com/lodging/115000000/114120000/114116400/114116366/b82a5191.jpg?impolicy=fcrop&w=357&h=201&p=1&q=medium) ![Full-size fridge, microwave, stovetop, coffee/tea maker](https://images.trvl-media.com/lodging/115000000/114120000/114116400/114116366/w2000h1293x0y90-00acac65.jpg?impolicy=fcrop&w=357&h=201&p=1&q=medium) ![Rooftop terrace](https://images.trvl-media.com/lodging/115000000/114120000/114116400/114116366/dd5fc603.jpg?impolicy=fcrop&w=357&h=201&p=1&q=medium) ![Lobby](https://images.trvl-media.com/lodging/115000000/114120000/114116400/114116366/d0f0db5f.jpg?impolicy=fcrop&w=357&h=201&p=1&q=medium) ### Sentral Gaslamp Quarter Downtown San Diego 9.2/10 Wonderful (505) "Great place to stay. " ![United States](https://a.travel-assets.com/egds/marks/flags/us.svg) Gary CA $184 CA $254 total includes taxes & fees Nov 9 - Nov 10 [](https://www.expedia.ca/San-Diego-Hotels-Sentral-Gaslamp-Quarter.h114116366.Hotel-Information) ![Reception](https://images.trvl-media.com/lodging/13000000/12970000/12963400/12963301/cc52443d.jpg?impolicy=fcrop&w=357&h=201&p=1&q=medium) ![Lobby lounge](https://images.trvl-media.com/lodging/13000000/12970000/12963400/12963301/1375264c.jpg?impolicy=fcrop&w=357&h=201&p=1&q=medium) ![Lobby](https://images.trvl-media.com/lodging/13000000/12970000/12963400/12963301/w3837h2557x3y3-af97ac41.jpg?impolicy=fcrop&w=357&h=201&p=1&q=medium) ![Premium bedding, Tempur-Pedic beds, desk, laptop workspace](https://images.trvl-media.com/lodging/13000000/12970000/12963400/12963301/w3837h2557x3y3-1277fb5d.jpg?impolicy=fcrop&w=357&h=201&p=1&q=medium) ### Hampton Inn & Suites by Hilton San Diego SeaWorld Point Loma 9.0/10 Wonderful (212) "Would definitely stay here again !" ![United States](https://a.travel-assets.com/egds/marks/flags/us.svg) Joshua CA $148 CA $170 total includes taxes & fees Nov 10 - Nov 11 [](https://www.expedia.ca/San-Diego-Hotels-Hampton-Inn-Suites-San-Diego-Point-Loma.h12963301.Hotel-Information) ![Outdoor pool, open 9:00 AM to 9:00 PM, pool umbrellas, sun loungers](https://images.trvl-media.com/lodging/1000000/1000000/996200/996144/a653b43a.jpg?impolicy=fcrop&w=357&h=201&p=1&q=medium) ![Lobby](https://images.trvl-media.com/lodging/1000000/1000000/996200/996144/63e66623.jpg?impolicy=fcrop&w=357&h=201&p=1&q=medium) ![Exterior](https://images.trvl-media.com/lodging/1000000/1000000/996200/996144/4e3a5f44.jpg?impolicy=fcrop&w=357&h=201&p=1&q=medium) ![Blackout drapes, iron/ironing board, free WiFi, bed sheets](https://images.trvl-media.com/lodging/1000000/1000000/996200/996144/6a0c40cf.jpg?impolicy=fcrop&w=357&h=201&p=1&q=medium) ### Motel 6 El Cajon, CA - San Diego El Cajon 7.2/10 Good (1434) "Great rooms for price " ![United States](https://a.travel-assets.com/egds/marks/flags/us.svg) Jerod CA $86 CA $94 total includes taxes & fees Nov 9 - Nov 10 [](https://www.expedia.ca/El-Cajon-Hotels-Motel-6-El-Cajon.h996144.Hotel-Information) ![Premium bedding, desk, iron/ironing board, cribs/infant beds](https://images.trvl-media.com/lodging/1000000/30000/27100/27004/f9b24de7.jpg?impolicy=fcrop&w=357&h=201&p=1&q=medium) ![Exterior](https://images.trvl-media.com/lodging/1000000/30000/27100/27004/99cabaa0.jpg?impolicy=fcrop&w=357&h=201&p=1&q=medium) ![Suite, 1 King Bed with Sofa bed, Non Smoking, Kitchenette (with Sofabed) | Private kitchen](https://images.trvl-media.com/lodging/1000000/30000/27100/27004/55f4cf2e.jpg?impolicy=fcrop&w=357&h=201&p=1&q=medium) ![Reception](https://images.trvl-media.com/lodging/1000000/30000/27100/27004/123624b2.jpg?impolicy=fcrop&w=357&h=201&p=1&q=medium) ### Best Western Santee Lodge Santee 7.8/10 Good (575) "Staff was excellent. " ![United States](https://a.travel-assets.com/egds/marks/flags/us.svg) Anthony CA $138 CA $152 total includes taxes & fees Nov 2 - Nov 3 [](https://www.expedia.ca/Santee-Hotels-Best-Western-Santee-Lodge.h27004.Hotel-Information) ![Suite, 1 Queen Bed with Sofa bed, Kitchenette](https://images.trvl-media.com/lodging/2000000/1220000/1215300/1215233/764ad8f4.jpg?impolicy=fcrop&w=357&h=201&p=1&q=medium) ![Property grounds](https://images.trvl-media.com/lodging/2000000/1220000/1215300/1215233/f5865630.jpg?impolicy=fcrop&w=357&h=201&p=1&q=medium) ![Exterior](https://images.trvl-media.com/lodging/2000000/1220000/1215300/1215233/0e7b15cb.jpg?impolicy=fcrop&w=357&h=201&p=1&q=medium) ![Fridge, microwave, coffee/tea maker](https://images.trvl-media.com/lodging/2000000/1220000/1215300/1215233/16dacb17.jpg?impolicy=fcrop&w=357&h=201&p=1&q=medium) ### Hotel Point Loma Point Loma 7.4/10 Good (314) "It was nice, spacious & clean" ![United States](https://a.travel-assets.com/egds/marks/flags/us.svg) Mark CA $100 CA $113 total includes taxes & fees Nov 2 - Nov 3 [](https://www.expedia.ca/San-Diego-Hotels-Hotel-Point-Loma.h1215233.Hotel-Information) ![Marina](https://images.trvl-media.com/lodging/1000000/60000/57300/57254/80f275da.jpg?impolicy=fcrop&w=357&h=201&p=1&q=medium) ![Aerial view](https://images.trvl-media.com/lodging/1000000/60000/57300/57254/42d1a51f.jpg?impolicy=fcrop&w=357&h=201&p=1&q=medium) ![Deluxe Room, 2 Queen Beds, Harbour View](https://images.trvl-media.com/lodging/1000000/60000/57300/57254/f8a54f53.jpg?impolicy=fcrop&w=357&h=201&p=1&q=medium) ![Aerial view](https://images.trvl-media.com/lodging/1000000/60000/57300/57254/ecc06b6b.jpg?impolicy=fcrop&w=357&h=201&p=1&q=medium) ### Sea Harbor Hotel Point Loma 8.6/10 Excellent (1032) "Great location" ![United States](https://a.travel-assets.com/egds/marks/flags/us.svg) Ruben CA $128 CA $145 total includes taxes & fees Nov 9 - Nov 10 [](https://www.expedia.ca/San-Diego-Hotels-Sea-Harbor-Hotel.h57254.Hotel-Information) ![Seasonal outdoor pool, a heated pool](https://images.trvl-media.com/lodging/2000000/1050000/1047500/1047474/0c3fb187.jpg?impolicy=fcrop&w=357&h=201&p=1&q=medium) ![Premium Room, 1 King Bed, Non Smoking, Ocean View (Non-Pet friendly)](https://images.trvl-media.com/lodging/2000000/1050000/1047500/1047474/3cee5c4d.jpg?impolicy=fcrop&w=357&h=201&p=1&q=medium) ![Property grounds](https://images.trvl-media.com/lodging/2000000/1050000/1047500/1047474/27276731.jpg?impolicy=fcrop&w=357&h=201&p=1&q=medium) ![Pet-friendly](https://images.trvl-media.com/lodging/2000000/1050000/1047500/1047474/aac48c50.jpg?impolicy=fcrop&w=357&h=201&p=1&q=medium) ### Ocean Villa Inn Ocean Beach 8.2/10 Very good (1102) "Room was cute, staff helpful. Location to the beach was excellent " ![United States](https://a.travel-assets.com/egds/marks/flags/us.svg) Kenta [](https://www.expedia.ca/San-Diego-Hotels-Ocean-Villa-Inn.h1047474.Hotel-Information) ![Outdoor pool, pool umbrellas, sun loungers](https://images.trvl-media.com/lodging/1000000/470000/461200/461101/f85548dd.jpg?impolicy=fcrop&w=357&h=201&p=1&q=medium) ![Lobby sitting area](https://images.trvl-media.com/lodging/1000000/470000/461200/461101/8acfb37a.jpg?impolicy=fcrop&w=357&h=201&p=1&q=medium) ![Single Queen Room, Accessible w/ Kitchen](https://images.trvl-media.com/lodging/1000000/470000/461200/461101/dfd12221.jpg?impolicy=fcrop&w=357&h=201&p=1&q=medium) ![Reception](https://images.trvl-media.com/lodging/1000000/470000/461200/461101/8da6f7c1.jpg?impolicy=fcrop&w=357&h=201&p=1&q=medium) ### Lamplighter Inn & Suites at SDSU Mid-City 9.0/10 Wonderful (1274) "Staff was very nice and the property is well maintained. " ![United States](https://a.travel-assets.com/egds/marks/flags/us.svg) Jeffrey CA $114 CA $129 total includes taxes & fees Nov 14 - Nov 15 [](https://www.expedia.ca/San-Diego-Hotels-Lamplighter-Inn-Suites-At-SDSU.h461101.Hotel-Information) ![Exterior](https://images.trvl-media.com/lodging/14000000/13150000/13145800/13145727/cc4647fa.jpg?impolicy=fcrop&w=357&h=201&p=1&q=medium) ![In-room safe, desk, blackout drapes, iron/ironing board](https://images.trvl-media.com/lodging/14000000/13150000/13145800/13145727/8fb13e2f.jpg?impolicy=fcrop&w=357&h=201&p=1&q=medium) ![Lobby](https://images.trvl-media.com/lodging/14000000/13150000/13145800/13145727/0f7253f1.jpg?impolicy=fcrop&w=357&h=201&p=1&q=medium) ![View from room](https://images.trvl-media.com/lodging/14000000/13150000/13145800/13145727/9a0a7909.jpg?impolicy=fcrop&w=357&h=201&p=1&q=medium) ### Hilton Garden Inn San Diego Mission Valley Stadium Kearny Mesa 8.0/10 Very good (1003) "Clean room, friendly staff. " ![United States](https://a.travel-assets.com/egds/marks/flags/us.svg) Steve CA $144 CA $165 total includes taxes & fees Nov 30 - Dec 1 [](https://www.expedia.ca/San-Diego-Hotels-Hilton-Garden-Inn-San-Diego-Mission-Valley-Stadium.h13145727.Hotel-Information) ![Exterior](https://images.trvl-media.com/lodging/1000000/30000/22900/22810/bfd1ccfe.jpg?impolicy=fcrop&w=357&h=201&p=1&q=medium) ![Free continental breakfast](https://images.trvl-media.com/lodging/1000000/30000/22900/22810/84883664.jpg?impolicy=fcrop&w=357&h=201&p=1&q=medium) ![Outdoor pool, sun loungers](https://images.trvl-media.com/lodging/1000000/30000/22900/22810/2194e09f.jpg?impolicy=fcrop&w=357&h=201&p=1&q=medium) ![Deluxe Room, 1 King Bed, Non Smoking](https://images.trvl-media.com/lodging/1000000/30000/22900/22810/b3ebadf5.jpg?impolicy=fcrop&w=357&h=201&p=1&q=medium) ### La Quinta Inn by Wyndham San Diego Chula Vista Chula Vista 8.6/10 Excellent (1441) "Very clean, staff was very helpful, Parking was great I forgot about breakfast." ![United States](https://a.travel-assets.com/egds/marks/flags/us.svg) Martha CA $137 CA $150 total includes taxes & fees Nov 2 - Nov 3 [](https://www.expedia.ca/Chula-Vista-Hotels-La-Quinta-Inn-By-Wyndham-San-Diego-Chula-Vista.h22810.Hotel-Information) Lowest nightly price found within the past 24 hours based on a 1 night stay for 2 adults. Prices and availability subject to change. Additional terms may apply. [View all properties](https://expedia.ca/Hotel-Search?startDate=2025-11-13&endDate=2025-11-14®ionId=6263723&adults=2&amenities=PETS&sort=RECOMMENDED&openPlayBack=true) ## Top Otay Mesa Hotel Reviews ![Wyndham Garden San Diego Near SeaWorld](//images.trvl-media.com/lodging/1000000/50000/41000/40962/76b78879_y.jpg) ### Wyndham Garden San Diego Near SeaWorld 10/10 Excellent "The staff were friendly. The room was clean but there were some issues in the room. Shower head was not completely sealed. There there spots on the ceiling in the bathroom and the some baseboards were messed up. " [](https://expedia.ca/San-Diego-Hotels-Wyndham-Garden-San-Diego-Near-SeaWorld.h40962.Hotel-Information) ![Hilton San Diego Mission Valley](//images.trvl-media.com/lodging/1000000/20000/16100/16019/w3839h2160x1y0-98566ca3_y.jpg) ### Hilton San Diego Mission Valley 10/10 Excellent "standard room, only thing we kind of have issues with was our key wasn't working properly when leaving the parking, so we would just press on the call button then they'll eventually open the gate." [](https://expedia.ca/San-Diego-Hotels-Hilton-San-Diego-Mission-Valley.h16019.Hotel-Information) ![The Dana on Mission Bay](//images.trvl-media.com/lodging/1000000/50000/41000/40953/08585098_y.jpg) ### The Dana on Mission Bay 10/10 Excellent "Comfortable beds and good sized rooms. Property is outdat" [](https://expedia.ca/San-Diego-Hotels-The-Dana-On-Mission-Bay.h40953.Hotel-Information) ![Wyndham San Diego Bayside](//images.trvl-media.com/lodging/1000000/20000/11200/11177/c44ff51d_y.jpg) ### Wyndham San Diego Bayside 10/10 Excellent "Yes" [](https://expedia.ca/San-Diego-Hotels-Wyndham-San-Diego-Bayside.h11177.Hotel-Information) ![Manchester Grand Hyatt San Diego](//images.trvl-media.com/lodging/1000000/20000/12100/12073/w3840h2092x0y3-447c77a4_y.jpg) ### Manchester Grand Hyatt San Diego 10/10 Excellent "Staff was friendly and room was clean " [](https://expedia.ca/San-Diego-Hotels-Manchester-Grand-Hyatt-San-Diego.h12073.Hotel-Information) ![Pendry San Diego](//images.trvl-media.com/lodging/17000000/16300000/16299000/16298963/05d0e601_y.jpg) ### Pendry San Diego 10/10 Excellent "The rooms were very nice and the location is perfect for San Diego. It's a very nice hotel." [](https://expedia.ca/San-Diego-Hotels-Pendry-San-Diego.h16298963.Hotel-Information) ## Frequently asked questions ### What is there to see and do with your pet in Otay Mesa? > Known for its rich culture, Otay Mesa has lots to offer visitors including its theaters and sports. During your visit, enjoy checking out San Diego Convention Center and San Ysidro Border Crossing. When you're in the area, make time for a stop at top attractions like Hotel del Coronado and Petco Park. ## Explore a world of travel with Expedia - Lodging - More ways to book - [Beach Hotel Hotels in Camp Pendleton Marine Corps Base](https://www.expedia.ca/Camp-Pendleton-Marine-Corps-Base-Hotels-Beach-Hotel.0-0-d6068523-tBeachHotel.Travel-Guide-Filter-Hotels) - [Hotels with Early Check-in in Camp Pendleton Marine Corps Base](https://www.expedia.ca/Camp-Pendleton-Marine-Corps-Base-Hotels-Hotel-With-Early-Check-In.0-0-d6068523-thotelwithearlycheckin.Travel-Guide-Filter-Hotels) - [Hotels with an Indoor Pool in Camp Pendleton Marine Corps Base](https://www.expedia.ca/Camp-Pendleton-Marine-Corps-Base-Hotels-Hotels-With-Indoor-Pool.0-0-d6068523-tHotelswithIndoorPool.Travel-Guide-Filter-Hotels) - [Luxury Hotels in Camp Pendleton Marine Corps Base](https://www.expedia.ca/Camp-Pendleton-Marine-Corps-Base-Hotels-Luxury-Hotel.0-0-d6068523-tLuxuryHotel.Travel-Guide-Filter-Hotels) - [Oceanfront Hotels in Camp Pendleton Marine Corps Base](https://www.expedia.ca/Camp-Pendleton-Marine-Corps-Base-Hotels-Oceanfront-Hotels.0-0-d6068523-tOceanfrontHotels.Travel-Guide-Filter-Hotels) - 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