Title: Book the Best Otay Mesa LUXURY Hotels - Upscale Hotels in Otay Mesa, San Diego | Expedia.ca

[Vacation Rentals in San Diego](https://expedia.ca/San-Diego-Vacation-Rentals.d3073.Travel-Guide-VacationRentals)[Flights to San Diego](https://expedia.ca/Cheap-Flights-To-San-Diego.d3073.Travel-Guide-Flights)[Things to do in San Diego](https://expedia.ca/Things-To-Do-In-San-Diego.d3073.Travel-Guide-Activities)[Otay Mesa Car Rentals](https://expedia.ca/Car-Rentals-In-Otay-Mesa.d6263723.Car-Rental-Guide)[Otay Mesa Vacations](https://expedia.ca/Otay-Mesa.d6263723.Destination-Travel-Guides)

![Tijuana Neighborhood Seen Over Border Fence](https://images.trvl-media.com/place/6263723/a421f2e3-03d1-46f6-89f3-1009103bee11.jpg?impolicy=fcrop&w=1200&h=500&q=medium)

# Find Luxury Hotels in Otay Mesa, San Diego

- ![](https://a.travel-assets.com/travel-assets-manager/pictogram-bex/light__calendar_shield.svg)  
###  
Change your mind  
Book hotels with free cancellation
- ![](https://a.travel-assets.com/travel-assets-manager/pictogram-bex/light__deals.svg)  
###  
Treat yourself  
Sign in to save 10% or more on thousands of hotels  
[Sign in](https://www.expedia.ca/login)
- ![](https://a.travel-assets.com/travel-assets-manager/pictogram-bex/light__bed.svg)  
###  
Be picky  
Search almost a million properties worldwide

## Check availability on Otay Mesa Luxury Hotels

Tonight

[Dec 27 - Dec 28](https://www.expedia.ca/Hotel-Search?regionId=6263723&startDate=2025-12-27&endDate=2025-12-28&adults=2&propertyStyle=LUXURY&rfrr=TG.LP.CheckPrices.Hotel&openPlayBack=true&travelerType=luxury_property)

Tomorrow

[Dec 28 - Dec 29](https://www.expedia.ca/Hotel-Search?regionId=6263723&startDate=2025-12-28&endDate=2025-12-29&adults=2&propertyStyle=LUXURY&rfrr=TG.LP.CheckPrices.Hotel&openPlayBack=true&travelerType=luxury_property)

Next weekend

[Jan 2 - Jan 4](https://www.expedia.ca/Hotel-Search?regionId=6263723&startDate=2026-01-02&endDate=2026-01-04&adults=2&propertyStyle=LUXURY&rfrr=TG.LP.CheckPrices.Hotel&openPlayBack=true&travelerType=luxury_property)

In two weeks

[Jan 9 - Jan 11](https://www.expedia.ca/Hotel-Search?regionId=6263723&startDate=2026-01-09&endDate=2026-01-11&adults=2&propertyStyle=LUXURY&rfrr=TG.LP.CheckPrices.Hotel&openPlayBack=true&travelerType=luxury_property)

## Our top choices for Otay Mesa luxury hotels

![Desk, laptop workspace, blackout drapes, iron/ironing board](https://images.trvl-media.com/lodging/1000000/470000/461900/461837/673df2c4.jpg?impolicy=fcrop&w=357&h=201&p=1&q=medium)

![Lobby](https://images.trvl-media.com/lodging/1000000/470000/461900/461837/16237f85.jpg?impolicy=fcrop&w=357&h=201&p=1&q=medium)

![Desk, laptop workspace, blackout drapes, iron/ironing board](https://images.trvl-media.com/lodging/1000000/470000/461900/461837/55248c07.jpg?impolicy=fcrop&w=357&h=201&p=1&q=medium)

![Lobby](https://images.trvl-media.com/lodging/1000000/470000/461900/461837/c6a042c7.jpg?impolicy=fcrop&w=357&h=201&p=1&q=medium)

### Quality Suites San Diego Otay Mesa

[](https://www.expedia.ca/San-Diego-Hotels-Quality-Suites-San-Diego-Otay-Mesa.h461837.Hotel-Information)

Otay Mesa

7.2/10

Good

(1001)

"Beautiful place "

![United States](https://a.travel-assets.com/egds/marks/flags/us.svg)

Joe

CA $135

CA $154 total

includes taxes & fees

Dec 28 - Dec 29

[](https://www.expedia.ca/San-Diego-Hotels-Quality-Suites-San-Diego-Otay-Mesa.h461837.Hotel-Information)

Lowest nightly price found within the past 24 hours based on a 1 night stay for 2 adults. Prices and availability subject to change. Additional terms may apply.

[View all properties](https://expedia.ca/Hotel-Search?startDate=2026-01-10&endDate=2026-01-11&regionId=6263723&adults=2&star=50&sort=RECOMMENDED&openPlayBack=true)

## Top Otay Mesa Hotel Reviews

![Kings Inn San Diego](https://images.trvl-media.com/lodging/1000000/20000/17000/16910/a5f26080_y.jpg)

### Kings Inn San Diego

10/10 Excellent

"Our stays here have always been great. That trend continues. Great services all the way around"

[](https://expedia.ca/San-Diego-Hotels-Kings-Inn-San-Diego-Seaworld-Zoo.h16910.Hotel-Information)

![Courtyard by Marriott San Diego Downtown Little Italy](https://images.trvl-media.com/lodging/1000000/20000/13300/13205/db3040ff_y.jpg)

### Courtyard by Marriott San Diego Downtown Little Italy

10/10 Excellent

"Excellent "

[](https://expedia.ca/San-Diego-Hotels-The-Little-Italy-Hotel-In-Downtown-San-Diego.h13205.Hotel-Information)

![Hotel del Coronado, Curio Collection by Hilton](https://images.trvl-media.com/lodging/1000000/10000/7500/7496/20fe4d95_y.jpg)

### Hotel del Coronado, Curio Collection by Hilton

10/10 Excellent

"Stayed here w my wife and two kids for a long weekend. The property and location are 5 star. The food and drinks are better than most resorts. Looking forward to coming back. "

[](https://expedia.ca/Coronado-Hotels-Hotel-Del-Coronado.h7496.Hotel-Information)

![Days Inn by Wyndham San Diego Hotel Circle](https://images.trvl-media.com/lodging/1000000/20000/19300/19220/3334d773_y.jpg)

### Days Inn by Wyndham San Diego Hotel Circle

10/10 Excellent

"The room was very clean and comfortable and the staff were friendly and helpful. A great value! "

[](https://expedia.ca/San-Diego-Hotels-Days-Inn-By-Wyndham-San-Diego-Hotel-Circle.h19220.Hotel-Information)

![Bay Club Hotel & Marina](https://images.trvl-media.com/lodging/1000000/10000/2600/2514/8c022c3d_y.jpg)

### Bay Club Hotel & Marina

10/10 Excellent

"The location is great with easy access to places like SeaWorld, downtown gas lamp, zoo. I loved the view from the balcony. My wife and I will definitely come back to stay here. Oh and a nearby Tesla supercharger only 1.2miles from the hotel. "

[](https://expedia.ca/San-Diego-Hotels-Bay-Club-Hotel-Marina.h2514.Hotel-Information)

![Margaritaville Hotel San Diego Gaslamp Quarter](https://images.trvl-media.com/lodging/2000000/1120000/1117700/1117693/0db99a00_y.jpg)

### Margaritaville Hotel San Diego Gaslamp Quarter

10/10 Excellent

"Everything was great except there were early morning street noise that tended to wake me up. "

[](https://expedia.ca/San-Diego-Hotels-Solamar-San-Diego.h1117693.Hotel-Information)

![The Dana on Mission Bay](https://images.trvl-media.com/lodging/1000000/50000/41000/40953/08585098_y.jpg)

### The Dana on Mission Bay

10/10 Excellent

"The staff members are very helpful. When I talked to them the pillows are a little bit firm to me because I like the very soft pillows they quickly brought me two down filled softer pillows to me. The room is very clean and the garden view is so beautiful. We all felt comfortable and relaxed when we were leaving at The Dana. Thanks for your best service! We will be back when we visit San Diego next time."

[](https://expedia.ca/San-Diego-Hotels-The-Dana-On-Mission-Bay.h40953.Hotel-Information)

![Best Western Plus Marina Gateway Hotel](https://images.trvl-media.com/lodging/3000000/2820000/2816700/2816688/f3777dfe_y.jpg)

### Best Western Plus Marina Gateway Hotel

10/10 Excellent

"Staff is very friendly , property very clean and the room is awesome. Highly recommend "

[](https://expedia.ca/National-City-Hotels-Best-Western-Plus-Marina-Gateway-Hotel.h2816688.Hotel-Information)

![Best Western Seven Seas](https://images.trvl-media.com/lodging/1000000/10000/1800/1734/w3837h2556x3y3-8b148daf_y.jpg)

### Best Western Seven Seas

10/10 Excellent

"Great staff"

[](https://expedia.ca/San-Diego-Hotels-Best-Western-Seven-Seas.h1734.Hotel-Information)

## Frequently asked questions

### Are you searching for the perfect hotel for your luxury getaway to Otay Mesa?

### What's there to see and do in Otay Mesa?

## Explore a world of travel with Expedia

- Lodging
- More ways to book

- [Beach Hotel Hotels in Camp Pendleton Marine Corps Base ](https://www.expedia.ca/Camp-Pendleton-Marine-Corps-Base-Hotels-Beach-Hotel.0-0-d6068523-tBeachHotel.Travel-Guide-Filter-Hotels)
- [Hotels with Early Check-in in Camp Pendleton Marine Corps Base ](https://www.expedia.ca/Camp-Pendleton-Marine-Corps-Base-Hotels-Hotel-With-Early-Check-In.0-0-d6068523-thotelwithearlycheckin.Travel-Guide-Filter-Hotels)
- [Hotels with an Indoor Pool in Camp Pendleton Marine Corps Base ](https://www.expedia.ca/Camp-Pendleton-Marine-Corps-Base-Hotels-Hotels-With-Indoor-Pool.0-0-d6068523-tHotelswithIndoorPool.Travel-Guide-Filter-Hotels)
- [Luxury Hotels in Camp Pendleton Marine Corps Base ](https://www.expedia.ca/Camp-Pendleton-Marine-Corps-Base-Hotels-Luxury-Hotel.0-0-d6068523-tLuxuryHotel.Travel-Guide-Filter-Hotels)
- [Oceanfront Hotels in Camp Pendleton Marine Corps Base ](https://www.expedia.ca/Camp-Pendleton-Marine-Corps-Base-Hotels-Oceanfront-Hotels.0-0-d6068523-tOceanfrontHotels.Travel-Guide-Filter-Hotels)
- [Ski Hotels in Camp Pendleton Marine Corps Base ](https://www.expedia.ca/Camp-Pendleton-Marine-Corps-Base-Hotels-Ski-Hotel.0-0-d6068523-tSkiHotel.Travel-Guide-Filter-Hotels)
- [Hotels & Resorts for Couples in Carlsbad ](https://www.expedia.ca/Carlsbad-Hotels-Couples-Resorts-Hotels.0-0-d6056550-tCouplesResortsHotels.Travel-Guide-Filter-Hotels)
- [Hotels with Early Check-in in Carlsbad ](https://www.expedia.ca/Carlsbad-Hotels-Hotel-With-Early-Check-In.0-0-d6056550-thotelwithearlycheckin.Travel-Guide-Filter-Hotels)
- [Hotels with Hot Tubs in Carlsbad ](https://www.expedia.ca/Carlsbad-Hotels-Hotels-With-Hot-Tubs.0-0-d6056550-tHotelsWithHotTubs.Travel-Guide-Filter-Hotels)
- [Lake Hotels in Carlsbad ](https://www.expedia.ca/Carlsbad-Hotels-Lake-Hotels.0-0-d6056550-tLakeHotels.Travel-Guide-Filter-Hotels)
- [Scuba Diving Hotels in Carlsbad ](https://www.expedia.ca/Carlsbad-Hotels-Scuba-Diving-Vacations.0-0-d6056550-tscubadivingvacations.Travel-Guide-Filter-Hotels)
- [Winery Hotels in Carlsbad ](https://www.expedia.ca/Carlsbad-Hotels-Winery-Hotel.0-0-d6056550-tWineryHotel.Travel-Guide-Filter-Hotels)
- [Casino Hotels in Chula Vista ](https://www.expedia.ca/Chula-Vista-Hotels-Casino-Hotel.0-0-d7442-tCasinoHotel.Travel-Guide-Filter-Hotels)
- [Hotels with Hot Tubs in Chula Vista ](https://www.expedia.ca/Chula-Vista-Hotels-Hotels-With-Hot-Tubs.0-0-d7442-tHotelsWithHotTubs.Travel-Guide-Filter-Hotels)
- [Spa Hotels in Chula Vista ](https://www.expedia.ca/Chula-Vista-Hotels-Spa-Hotel.0-0-d7442-tSpaHotel.Travel-Guide-Filter-Hotels)
- [Green Hotels in San Diego County ](https://www.expedia.ca/Destinations-In-San-Diego-County-Green-Sustainable.0-0-d178304-tGreenSustainable.Hotel-Filter-Destinations)
- [Hotels with Wifi in San Diego County ](https://www.expedia.ca/Destinations-In-San-Diego-County-Hotel-With-Wifi.0-0-d178304-tHotelwithwifi.Hotel-Filter-Destinations)
- [Hotels with Bar in San Diego County ](https://www.expedia.ca/Destinations-In-San-Diego-County-Hotels-With-Bar.0-0-d178304-tHotelswithBar.Hotel-Filter-Destinations)
- [Hotels with Childcare in San Diego County ](https://www.expedia.ca/Destinations-In-San-Diego-County-Hotels-With-Childcare.0-0-d178304-tHotelswithChildcare.Hotel-Filter-Destinations)
- [Hotels with Free Breakfast in San Diego County ](https://www.expedia.ca/Destinations-In-San-Diego-County-Hotels-With-Free-Breakfast.0-0-d178304-tHotelswithFreeBreakfast.Hotel-Filter-Destinations)
- [Hotels with Free Parking in San Diego County ](https://www.expedia.ca/Destinations-In-San-Diego-County-Hotels-With-Free-Parking.0-0-d178304-tHotelswithFreeParking.Hotel-Filter-Destinations)
- [Hotels with Hot Tubs in San Diego County ](https://www.expedia.ca/Destinations-In-San-Diego-County-Hotels-With-Hot-Tubs.0-0-d178304-tHotelsWithHotTubs.Hotel-Filter-Destinations)
- [Hotels with smoking rooms in San Diego County ](https://www.expedia.ca/Destinations-In-San-Diego-County-Hotels-With-Smoking-Rooms.0-0-d178304-tHotelswithsmokingrooms.Hotel-Filter-Destinations)
- [Lgbt Friendly Hotels in San Diego County ](https://www.expedia.ca/Destinations-In-San-Diego-County-LGBT-Friendly-Hotel.0-0-d178304-tLGBTFriendlyHotel.Hotel-Filter-Destinations)
- [Scuba Diving Hotels in San Diego County ](https://www.expedia.ca/Destinations-In-San-Diego-County-Scuba-Diving-Vacations.0-0-d178304-tscubadivingvacations.Hotel-Filter-Destinations)
- [Shopping Hotels in San Diego County ](https://www.expedia.ca/Destinations-In-San-Diego-County-Shopping-Hotel.0-0-d178304-tShoppingHotel.Hotel-Filter-Destinations)
- [Hotel Wedding Venues Hotels in San Diego County ](https://www.expedia.ca/Destinations-In-San-Diego-County-Wedding-Hotels.0-0-d178304-tWeddingHotels.Hotel-Filter-Destinations)
- [Adults Only Resorts & in Downtown San Diego ](https://www.expedia.ca/Downtown-San-Diego-San-Diego-Hotels-Adults-Only-Resorts.0-n800123-0-tAdultsOnlyResorts.Travel-Guide-Filter-Hotels)
- [Hotels & Resorts for Couples in Downtown San Diego ](https://www.expedia.ca/Downtown-San-Diego-San-Diego-Hotels-Couples-Resorts-Hotels.0-n800123-0-tCouplesResortsHotels.Travel-Guide-Filter-Hotels)
- [Golf Hotels in Downtown San Diego ](https://www.expedia.ca/Downtown-San-Diego-San-Diego-Hotels-Golf-Hotel.0-n800123-0-tGolfHotel.Travel-Guide-Filter-Hotels)
- [Hotels with Wifi in Downtown San Diego ](https://www.expedia.ca/Downtown-San-Diego-San-Diego-Hotels-Hotel-With-Wifi.0-n800123-0-tHotelwithwifi.Travel-Guide-Filter-Hotels)
- [Hotels with a Lazy River in Downtown San Diego ](https://www.expedia.ca/Downtown-San-Diego-San-Diego-Hotels-Hotels-With-A-Lazy-River.0-n800123-0-tHotelswithaLazyRiver.Travel-Guide-Filter-Hotels)
- [Hotels with Balconies in Downtown San Diego ](https://www.expedia.ca/Downtown-San-Diego-San-Diego-Hotels-Hotels-With-Balconies.0-n800123-0-tHotelswithBalconies.Travel-Guide-Filter-Hotels)
- [Hotels with Bar in Downtown San Diego ](https://www.expedia.ca/Downtown-San-Diego-San-Diego-Hotels-Hotels-With-Bar.0-n800123-0-tHotelswithBar.Travel-Guide-Filter-Hotels)
- [Hotels with Free Breakfast in Downtown San Diego ](https://www.expedia.ca/Downtown-San-Diego-San-Diego-Hotels-Hotels-With-Free-Breakfast.0-n800123-0-tHotelswithFreeBreakfast.Travel-Guide-Filter-Hotels)
- [Hotels with Hot Tubs in Downtown San Diego ](https://www.expedia.ca/Downtown-San-Diego-San-Diego-Hotels-Hotels-With-Hot-Tubs.0-n800123-0-tHotelsWithHotTubs.Travel-Guide-Filter-Hotels)
- [Hotels with an Indoor Pool in Downtown San Diego ](https://www.expedia.ca/Downtown-San-Diego-San-Diego-Hotels-Hotels-With-Indoor-Pool.0-n800123-0-tHotelswithIndoorPool.Travel-Guide-Filter-Hotels)
- [Lgbt Friendly Hotels in Downtown San Diego ](https://www.expedia.ca/Downtown-San-Diego-San-Diego-Hotels-LGBT-Friendly-Hotel.0-n800123-0-tLGBTFriendlyHotel.Travel-Guide-Filter-Hotels)
- [Lake Hotels in Downtown San Diego ](https://www.expedia.ca/Downtown-San-Diego-San-Diego-Hotels-Lake-Hotels.0-n800123-0-tLakeHotels.Travel-Guide-Filter-Hotels)
- [Mountain Hotels in Downtown San Diego ](https://www.expedia.ca/Downtown-San-Diego-San-Diego-Hotels-Mountain-Hotels.0-n800123-0-tMountainHotels.Travel-Guide-Filter-Hotels)
- [Romantic Hotels in Downtown San Diego ](https://www.expedia.ca/Downtown-San-Diego-San-Diego-Hotels-Romantic-Hotel.0-n800123-0-tRomanticHotel.Travel-Guide-Filter-Hotels)
- [Scuba Diving Hotels in Downtown San Diego ](https://www.expedia.ca/Downtown-San-Diego-San-Diego-Hotels-Scuba-Diving-Vacations.0-n800123-0-tscubadivingvacations.Travel-Guide-Filter-Hotels)
- [Shopping Hotels in Downtown San Diego ](https://www.expedia.ca/Downtown-San-Diego-San-Diego-Hotels-Shopping-Hotel.0-n800123-0-tShoppingHotel.Travel-Guide-Filter-Hotels)
- [Spa Hotels in Downtown San Diego ](https://www.expedia.ca/Downtown-San-Diego-San-Diego-Hotels-Spa-Hotel.0-n800123-0-tSpaHotel.Travel-Guide-Filter-Hotels)
- [Waterpark Hotels in Downtown San Diego ](https://www.expedia.ca/Downtown-San-Diego-San-Diego-Hotels-Waterpark-Hotels.0-n800123-0-tWaterparkHotels.Travel-Guide-Filter-Hotels)
- [Winery Hotels in Downtown San Diego ](https://www.expedia.ca/Downtown-San-Diego-San-Diego-Hotels-Winery-Hotel.0-n800123-0-tWineryHotel.Travel-Guide-Filter-Hotels)
- [Green Hotels in Gaslamp Quarter ](https://www.expedia.ca/Gaslamp-Quarter-San-Diego-Hotels-Green-Sustainable.0-n6130021-0-tGreenSustainable.Travel-Guide-Filter-Hotels)
- [Hotels with Bar in Gaslamp Quarter ](https://www.expedia.ca/Gaslamp-Quarter-San-Diego-Hotels-Hotels-With-Bar.0-n6130021-0-tHotelswithBar.Travel-Guide-Filter-Hotels)
- [Waterpark Hotels in Gaslamp Quarter ](https://www.expedia.ca/Gaslamp-Quarter-San-Diego-Hotels-Waterpark-Hotels.0-n6130021-0-tWaterparkHotels.Travel-Guide-Filter-Hotels)
- [Scuba Diving Hotels in Laguna Beach ](https://www.expedia.ca/Laguna-Beach-Hotels-Scuba-Diving-Vacations.0-0-d8384-tscubadivingvacations.Travel-Guide-Filter-Hotels)
- [All Inclusive Resorts and in Ocean View Hills ](https://www.expedia.ca/Ocean-View-Hills-San-Diego-Hotels-All-Inclusive-Hotel.0-n553248635976008220-0-tAllInclusiveHotel.Travel-Guide-Filter-Hotels)
- [Beach Hotel Hotels in Ocean View Hills ](https://www.expedia.ca/Ocean-View-Hills-San-Diego-Hotels-Beach-Hotel.0-n553248635976008220-0-tBeachHotel.Travel-Guide-Filter-Hotels)
- [Hotels with Early Check-in in Ocean View Hills ](https://www.expedia.ca/Ocean-View-Hills-San-Diego-Hotels-Hotel-With-Early-Check-In.0-n553248635976008220-0-thotelwithearlycheckin.Travel-Guide-Filter-Hotels)
- [Hotels with Hot Tubs in Ocean View Hills ](https://www.expedia.ca/Ocean-View-Hills-San-Diego-Hotels-Hotels-With-Hot-Tubs.0-n553248635976008220-0-tHotelsWithHotTubs.Travel-Guide-Filter-Hotels)
- [Mountain Hotels in Ocean View Hills ](https://www.expedia.ca/Ocean-View-Hills-San-Diego-Hotels-Mountain-Hotels.0-n553248635976008220-0-tMountainHotels.Travel-Guide-Filter-Hotels)
- [Oceanfront Hotels in Ocean View Hills ](https://www.expedia.ca/Ocean-View-Hills-San-Diego-Hotels-Oceanfront-Hotels.0-n553248635976008220-0-tOceanfrontHotels.Travel-Guide-Filter-Hotels)
- [Hotel Wedding Venues Hotels in Ocean View Hills ](https://www.expedia.ca/Ocean-View-Hills-San-Diego-Hotels-Wedding-Hotels.0-n553248635976008220-0-tWeddingHotels.Travel-Guide-Filter-Hotels)
- [Historic Hotels in Oceanside ](https://www.expedia.ca/Oceanside-Hotels-Historic-Hotel.0-0-d9154-tHistoricHotel.Travel-Guide-Filter-Hotels)
- [Hotels with Balconies in Oceanside ](https://www.expedia.ca/Oceanside-Hotels-Hotels-With-Balconies.0-0-d9154-tHotelswithBalconies.Travel-Guide-Filter-Hotels)
- [Hotels with Hot Tubs in Oceanside ](https://www.expedia.ca/Oceanside-Hotels-Hotels-With-Hot-Tubs.0-0-d9154-tHotelsWithHotTubs.Travel-Guide-Filter-Hotels)
- [Hotels with Balconies in Otay Mesa West ](https://www.expedia.ca/Otay-Mesa-West-San-Diego-Hotels-Hotels-With-Balconies.0-n553248625809641010-0-tHotelswithBalconies.Travel-Guide-Filter-Hotels)
- [Lgbt Friendly Hotels in Otay Ranch Village 1 ](https://www.expedia.ca/Otay-Ranch-Village-1-Chula-Vista-Hotels-LGBT-Friendly-Hotel.0-n553248635976473906-0-tLGBTFriendlyHotel.Travel-Guide-Filter-Hotels)
- [Lgbt Friendly Hotels in Otay Ranch Village West ](https://www.expedia.ca/Otay-Ranch-Village-West-Chula-Vista-Hotels-LGBT-Friendly-Hotel.0-n553248635976473051-0-tLGBTFriendlyHotel.Travel-Guide-Filter-Hotels)
- [Cheap Hotels in San Diego Coast ](https://www.expedia.ca/San-Diego-Coast-Hotels-Cheap-Hotels.0-0-d553248633966884021-tCheapHotels.Travel-Guide-Filter-Hotels)
- [Family Hotels in San Diego Coast ](https://www.expedia.ca/San-Diego-Coast-Hotels-Family-Hotel.0-0-d553248633966884021-tFamilyHotel.Travel-Guide-Filter-Hotels)
- [Green Hotels in San Diego Coast ](https://www.expedia.ca/San-Diego-Coast-Hotels-Green-Sustainable.0-0-d553248633966884021-tGreenSustainable.Travel-Guide-Filter-Hotels)
- [Hotels with Hot Tubs in San Diego Coast ](https://www.expedia.ca/San-Diego-Coast-Hotels-Hotels-With-Hot-Tubs.0-0-d553248633966884021-tHotelsWithHotTubs.Travel-Guide-Filter-Hotels)
- [Lake Hotels in San Diego Coast ](https://www.expedia.ca/San-Diego-Coast-Hotels-Lake-Hotels.0-0-d553248633966884021-tLakeHotels.Travel-Guide-Filter-Hotels)
- [Business Hotels in San Diego ](https://www.expedia.ca/San-Diego-Hotels-Business-Hotel.0-0-d3073-tBusinessHotel.Travel-Guide-Filter-Hotels)
- [Casino Hotels in San Diego ](https://www.expedia.ca/San-Diego-Hotels-Casino-Hotel.0-0-d3073-tCasinoHotel.Travel-Guide-Filter-Hotels)
- [Hotels & Resorts for Couples in San Diego ](https://www.expedia.ca/San-Diego-Hotels-Couples-Resorts-Hotels.0-0-d3073-tCouplesResortsHotels.Travel-Guide-Filter-Hotels)
- [Golf Hotels in San Diego ](https://www.expedia.ca/San-Diego-Hotels-Golf-Hotel.0-0-d3073-tGolfHotel.Travel-Guide-Filter-Hotels)
- [Green Hotels in San Diego ](https://www.expedia.ca/San-Diego-Hotels-Green-Sustainable.0-0-d3073-tGreenSustainable.Travel-Guide-Filter-Hotels)
- [Historic Hotels in San Diego ](https://www.expedia.ca/San-Diego-Hotels-Historic-Hotel.0-0-d3073-tHistoricHotel.Travel-Guide-Filter-Hotels)
- [Hotels with Wifi in San Diego ](https://www.expedia.ca/San-Diego-Hotels-Hotel-With-Wifi.0-0-d3073-tHotelwithwifi.Travel-Guide-Filter-Hotels)
- [Hotels with Bar in San Diego ](https://www.expedia.ca/San-Diego-Hotels-Hotels-With-Bar.0-0-d3073-tHotelswithBar.Travel-Guide-Filter-Hotels)
- [Hotels with Hot Tubs in San Diego ](https://www.expedia.ca/San-Diego-Hotels-Hotels-With-Hot-Tubs.0-0-d3073-tHotelsWithHotTubs.Travel-Guide-Filter-Hotels)
- [Lake Hotels in San Diego ](https://www.expedia.ca/San-Diego-Hotels-Lake-Hotels.0-0-d3073-tLakeHotels.Travel-Guide-Filter-Hotels)
- [Scuba Diving Hotels in San Diego ](https://www.expedia.ca/San-Diego-Hotels-Scuba-Diving-Vacations.0-0-d3073-tscubadivingvacations.Travel-Guide-Filter-Hotels)
- [Hotel Wedding Venues Hotels in San Diego ](https://www.expedia.ca/San-Diego-Hotels-Wedding-Hotels.0-0-d3073-tWeddingHotels.Travel-Guide-Filter-Hotels)
- [Boutique Hotels in San Ysidro ](https://www.expedia.ca/San-Ysidro-Hotels-Boutique-Hotel.0-0-d8380-tBoutiqueHotel.Travel-Guide-Filter-Hotels)
- [Business Hotels in San Ysidro ](https://www.expedia.ca/San-Ysidro-Hotels-Business-Hotel.0-0-d8380-tBusinessHotel.Travel-Guide-Filter-Hotels)
- [Cheap Hotels in San Ysidro ](https://www.expedia.ca/San-Ysidro-Hotels-Cheap-Hotels.0-0-d8380-tCheapHotels.Travel-Guide-Filter-Hotels)
- [Hotels & Resorts for Couples in San Ysidro ](https://www.expedia.ca/San-Ysidro-Hotels-Couples-Resorts-Hotels.0-0-d8380-tCouplesResortsHotels.Travel-Guide-Filter-Hotels)
- [Hotels with Early Check-in in San Ysidro ](https://www.expedia.ca/San-Ysidro-Hotels-Hotel-With-Early-Check-In.0-0-d8380-thotelwithearlycheckin.Travel-Guide-Filter-Hotels)
- [Hotels with Free Airport Shuttle in San Ysidro ](https://www.expedia.ca/San-Ysidro-Hotels-Hotels-With-Free-Airport-Shuttle.0-0-d8380-tHotelswithFreeAirportShuttle.Travel-Guide-Filter-Hotels)
- [Luxury Hotels in San Ysidro ](https://www.expedia.ca/San-Ysidro-Hotels-Luxury-Hotel.0-0-d8380-tLuxuryHotel.Travel-Guide-Filter-Hotels)
- [Pet-Friendly Hotels in San Ysidro ](https://www.expedia.ca/San-Ysidro-Hotels-Pet-Friendly-Hotel.0-0-d8380-tPetfriendlyHotel.Travel-Guide-Filter-Hotels)
- [Winery Hotels in San Ysidro ](https://www.expedia.ca/San-Ysidro-Hotels-Winery-Hotel.0-0-d8380-tWineryHotel.Travel-Guide-Filter-Hotels)
- [All Inclusive Resorts and in South Bay ](https://www.expedia.ca/South-Bay-Hotels-All-Inclusive-Hotel.0-0-d6056572-tAllInclusiveHotel.Travel-Guide-Filter-Hotels)
- [Beach Hotel Hotels in South Bay ](https://www.expedia.ca/South-Bay-Hotels-Beach-Hotel.0-0-d6056572-tBeachHotel.Travel-Guide-Filter-Hotels)
- [Boutique Hotels in South Bay ](https://www.expedia.ca/South-Bay-Hotels-Boutique-Hotel.0-0-d6056572-tBoutiqueHotel.Travel-Guide-Filter-Hotels)
- [Cheap Hotels in South Bay ](https://www.expedia.ca/South-Bay-Hotels-Cheap-Hotels.0-0-d6056572-tCheapHotels.Travel-Guide-Filter-Hotels)
- [Golf Hotels in South Bay ](https://www.expedia.ca/South-Bay-Hotels-Golf-Hotel.0-0-d6056572-tGolfHotel.Travel-Guide-Filter-Hotels)
- [Hotels with Kitchenettes in South Bay ](https://www.expedia.ca/South-Bay-Hotels-Hotels-With-Kitchenettes.0-0-d6056572-tHotelswithKitchenettes.Travel-Guide-Filter-Hotels)
- [Luxury Hotels in South Bay ](https://www.expedia.ca/South-Bay-Hotels-Luxury-Hotel.0-0-d6056572-tLuxuryHotel.Travel-Guide-Filter-Hotels)
- [Oceanfront Hotels in South Bay ](https://www.expedia.ca/South-Bay-Hotels-Oceanfront-Hotels.0-0-d6056572-tOceanfrontHotels.Travel-Guide-Filter-Hotels)
- [Pet-Friendly Hotels in South Bay ](https://www.expedia.ca/South-Bay-Hotels-Pet-Friendly-Hotel.0-0-d6056572-tPetfriendlyHotel.Travel-Guide-Filter-Hotels)
- [Spa Hotels in South Bay ](https://www.expedia.ca/South-Bay-Hotels-Spa-Hotel.0-0-d6056572-tSpaHotel.Travel-Guide-Filter-Hotels)
- [Winery Hotels in South Bay ](https://www.expedia.ca/South-Bay-Hotels-Winery-Hotel.0-0-d6056572-tWineryHotel.Travel-Guide-Filter-Hotels)

- [Book Hotels in Otay Mesa on Expedia.com ](https://www.expedia.com/Otay-Mesa-San-Diego-Hotels-Luxury-Hotel.0-n6263723-0-tLuxuryHotel.Travel-Guide-Filter-Hotels)