Title: Book the Best HISTORIC Hotels in Otay Mesa in 2026 | Expedia.ca [Vacation Rentals in San Diego](https://expedia.ca/San-Diego-Vacation-Rentals.d3073.Travel-Guide-VacationRentals)[Flights to San Diego](https://expedia.ca/Cheap-Flights-To-San-Diego.d3073.Travel-Guide-Flights)[Things to do in San Diego](https://expedia.ca/Things-To-Do-In-San-Diego.d3073.Travel-Guide-Activities)[Otay Mesa Car Rentals](https://expedia.ca/Car-Rentals-In-Otay-Mesa.d6263723.Car-Rental-Guide)[Otay Mesa Vacations](https://expedia.ca/Otay-Mesa.d6263723.Destination-Travel-Guides) ![Tijuana Neighborhood Seen Over Border Fence](https://images.trvl-media.com/place/6263723/a421f2e3-03d1-46f6-89f3-1009103bee11.jpg?impolicy=fcrop&w=1200&h=500&q=medium) # Find Historic Hotels in Otay Mesa, CA from CA $107 - ![](https://a.travel-assets.com/travel-assets-manager/pictogram-bex/light__calendar_shield.svg) ### Change your mind Book hotels with free cancellation - ![](https://a.travel-assets.com/travel-assets-manager/pictogram-bex/light__deals.svg) ### Treat yourself Sign in to save 10% or more on thousands of hotels [Sign in](https://www.expedia.ca/login) - ![](https://a.travel-assets.com/travel-assets-manager/pictogram-bex/light__bed.svg) ### Be picky Search almost a million properties worldwide ## Check availability on Otay Mesa Historic Hotels Tonight [Dec 18 - Dec 19](https://www.expedia.ca/Hotel-Search?regionId=6263723&startDate=2025-12-18&endDate=2025-12-19&adults=2&rfrr=TG.LP.CheckPrices.Hotel&openPlayBack=true) Tomorrow [Dec 19 - Dec 20](https://www.expedia.ca/Hotel-Search?regionId=6263723&startDate=2025-12-19&endDate=2025-12-20&adults=2&rfrr=TG.LP.CheckPrices.Hotel&openPlayBack=true) This weekend [Dec 19 - Dec 21](https://www.expedia.ca/Hotel-Search?regionId=6263723&startDate=2025-12-19&endDate=2025-12-21&adults=2&rfrr=TG.LP.CheckPrices.Hotel&openPlayBack=true) Next weekend [Dec 26 - Dec 28](https://www.expedia.ca/Hotel-Search?regionId=6263723&startDate=2025-12-26&endDate=2025-12-28&adults=2&rfrr=TG.LP.CheckPrices.Hotel&openPlayBack=true) ## Our top choices for Otay Mesa historic hotels ![Room, 1 King Bed, Accessible, Non Smoking (Mobility/Hearing Impaired)](https://images.trvl-media.com/lodging/1000000/10000/5000/4926/0dbfbf80.jpg?impolicy=fcrop&w=357&h=201&p=1&q=medium) ![Free daily on-the-go breakfast](https://images.trvl-media.com/lodging/1000000/10000/5000/4926/e35622ab.jpg?impolicy=fcrop&w=357&h=201&p=1&q=medium) ![Exterior](https://images.trvl-media.com/lodging/1000000/10000/5000/4926/30e922d6.jpg?impolicy=fcrop&w=357&h=201&p=1&q=medium) ![Lobby](https://images.trvl-media.com/lodging/1000000/10000/5000/4926/5feb0059.jpg?impolicy=fcrop&w=357&h=201&p=1&q=medium) ### Super 8 by Wyndham El Cajon/San Diego [](https://www.expedia.ca/El-Cajon-Hotels-Super-8-By-Wyndham-El-Cajon-CA.h4926.Hotel-Information) El Cajon 7.8/10 Good (1008) "vwey spacious and clean, great beds!" ![United States](https://a.travel-assets.com/egds/marks/flags/us.svg) Caroline CA $97 CA $107 total includes taxes & fees Dec 28 - Dec 29 [](https://www.expedia.ca/El-Cajon-Hotels-Super-8-By-Wyndham-El-Cajon-CA.h4926.Hotel-Information) ![Breakfast and dinner served, American cuisine](https://images.trvl-media.com/lodging/19000000/18970000/18961900/18961850/5c7cc72f.jpg?impolicy=fcrop&w=357&h=201&p=1&q=medium) ![Reception](https://images.trvl-media.com/lodging/19000000/18970000/18961900/18961850/d6f6a325.jpg?impolicy=fcrop&w=357&h=201&p=1&q=medium) ![Exterior](https://images.trvl-media.com/lodging/19000000/18970000/18961900/18961850/ac267ada.jpg?impolicy=fcrop&w=357&h=201&p=1&q=medium) ![Property amenity](https://images.trvl-media.com/lodging/19000000/18970000/18961900/18961850/782ee0d9.jpg?impolicy=fcrop&w=357&h=201&p=1&q=medium) ### Courtyard by Marriott San Diego El Cajon [](https://www.expedia.ca/El-Cajon-Hotels-Courtyard-By-Marriott-San-Diego-El-Cajon.h18961850.Hotel-Information) El Cajon 9.2/10 Wonderful (1000) "Very clean friendly staff " ![United States](https://a.travel-assets.com/egds/marks/flags/us.svg) salwa CA $226 CA $249 total includes taxes & fees Jan 5 - Jan 6, 2026 [](https://www.expedia.ca/El-Cajon-Hotels-Courtyard-By-Marriott-San-Diego-El-Cajon.h18961850.Hotel-Information) ![Deluxe 2 Queen with sofa sleeper | Bathroom](https://images.trvl-media.com/lodging/1000000/550000/548000/547983/b65c620d.jpg?impolicy=fcrop&w=357&h=201&p=1&q=medium) ![Lobby](https://images.trvl-media.com/lodging/1000000/550000/548000/547983/5fa97bc2.jpg?impolicy=fcrop&w=357&h=201&p=1&q=medium) ![Point of interest](https://images.trvl-media.com/lodging/1000000/550000/548000/547983/c47d4d2a.jpg?impolicy=fcrop&w=357&h=201&p=1&q=medium) ![Deluxe Room, 1 King Bed, Non Smoking, Refrigerator & Microwave](https://images.trvl-media.com/lodging/1000000/550000/548000/547983/f6db1f6c.jpg?impolicy=fcrop&w=357&h=201&p=1&q=medium) ### Old Town Western Inn & Suites [](https://www.expedia.ca/San-Diego-Hotels-Old-Town-Western-Inn-Suites.h547983.Hotel-Information) Old Town San Diego 7.6/10 Good (1008) "Friendly staff and clean rooms" ![United States](https://a.travel-assets.com/egds/marks/flags/us.svg) Lola CA $135 CA $152 total includes taxes & fees Dec 20 - Dec 21 [](https://www.expedia.ca/San-Diego-Hotels-Old-Town-Western-Inn-Suites.h547983.Hotel-Information) ![Lobby](https://images.trvl-media.com/lodging/1000000/20000/11900/11804/bb0553a3.jpg?impolicy=fcrop&w=357&h=201&p=1&q=medium) ![Free daily buffet breakfast](https://images.trvl-media.com/lodging/1000000/20000/11900/11804/156d3130.jpg?impolicy=fcrop&w=357&h=201&p=1&q=medium) ![Front of property - evening/night](https://images.trvl-media.com/lodging/1000000/20000/11900/11804/177cf1c4.jpg?impolicy=fcrop&w=357&h=201&p=1&q=medium) ![Courtyard](https://images.trvl-media.com/lodging/1000000/20000/11900/11804/fc74e47b.jpg?impolicy=fcrop&w=357&h=201&p=1&q=medium) ### Fairfield Inn & Suites San Diego Old Town [](https://www.expedia.ca/San-Diego-Hotels-Fairfield-Inn-Suites-San-Diego-Old-Town.h11804.Hotel-Information) Old Town San Diego 8.8/10 Excellent (1003) "Great stay, nice staff!" ![United States](https://a.travel-assets.com/egds/marks/flags/us.svg) Vaughn CA $153 CA $176 total includes taxes & fees Jan 4 - Jan 5, 2026 [](https://www.expedia.ca/San-Diego-Hotels-Fairfield-Inn-Suites-San-Diego-Old-Town.h11804.Hotel-Information) ![Standard Room, 2 Queen Beds](https://images.trvl-media.com/lodging/2000000/1610000/1606000/1605909/270b094d.jpg?impolicy=fcrop&w=357&h=201&p=1&q=medium) ![Desk, iron/ironing board, free WiFi, bed sheets](https://images.trvl-media.com/lodging/2000000/1610000/1606000/1605909/374ae34a.jpg?impolicy=fcrop&w=357&h=201&p=1&q=medium) ![Free self parking](https://images.trvl-media.com/lodging/2000000/1610000/1606000/1605909/a5127929.jpg?impolicy=fcrop&w=357&h=201&p=1&q=medium) ![Standard Room, 1 King Bed, Non Smoking | Exterior](https://images.trvl-media.com/lodging/2000000/1610000/1606000/1605909/067db95b.jpg?impolicy=fcrop&w=357&h=201&p=1&q=medium) ### Northgate Motel [](https://www.expedia.ca/El-Cajon-Hotels-Northgate-Motel.h1605909.Hotel-Information) El Cajon 7.8/10 Good (637) "Great air conditioner, nice rooms. Big comfortable beds. " ![United States](https://a.travel-assets.com/egds/marks/flags/us.svg) Michelle [](https://www.expedia.ca/El-Cajon-Hotels-Northgate-Motel.h1605909.Hotel-Information) ![2 outdoor pools, open 6 AM to 10:00 PM, cabanas (surcharge)](https://images.trvl-media.com/lodging/1000000/30000/24400/24394/9078a9ee.jpg?impolicy=fcrop&w=357&h=201&p=1&q=medium) ![Front of property - evening/night](https://images.trvl-media.com/lodging/1000000/30000/24400/24394/6dec3280.jpg?impolicy=fcrop&w=357&h=201&p=1&q=medium) ![Coffee/tea maker](https://images.trvl-media.com/lodging/1000000/30000/24400/24394/027f7247.jpg?impolicy=fcrop&w=357&h=201&p=1&q=medium) ![2 bars/lounges, poolside bar](https://images.trvl-media.com/lodging/1000000/30000/24400/24394/eb8b9673.jpg?impolicy=fcrop&w=357&h=201&p=1&q=medium) ### Marriott Marquis San Diego Marina [](https://www.expedia.ca/San-Diego-Hotels-Marriott-Marquis-San-Diego-Marina.h24394.Hotel-Information) Downtown San Diego 9.2/10 Wonderful (1947) "Amazing hotel Superb view Friendly staff Clean and neat rooms " ![United States](https://a.travel-assets.com/egds/marks/flags/us.svg) Chirag CA $219 CA $327 total includes taxes & fees Dec 25 - Dec 26 [](https://www.expedia.ca/San-Diego-Hotels-Marriott-Marquis-San-Diego-Marina.h24394.Hotel-Information) ![Exterior](https://images.trvl-media.com/lodging/1000000/920000/919100/919096/ed62594a.jpg?impolicy=fcrop&w=357&h=201&p=1&q=medium) ![Courtyard](https://images.trvl-media.com/lodging/1000000/920000/919100/919096/82d99d24.jpg?impolicy=fcrop&w=357&h=201&p=1&q=medium) ![Courtyard](https://images.trvl-media.com/lodging/1000000/920000/919100/919096/afa7d184.jpg?impolicy=fcrop&w=357&h=201&p=1&q=medium) ![Lobby](https://images.trvl-media.com/lodging/1000000/920000/919100/919096/e6a3b291.jpg?impolicy=fcrop&w=357&h=201&p=1&q=medium) ### Hilton Garden Inn San Diego Old Town/SeaWorld Area [](https://www.expedia.ca/San-Diego-Hotels-Hilton-Garden-Inn-San-Diego-Old-TownSeaWorld-Area.h919096.Hotel-Information) Old Town San Diego 8.6/10 Excellent (1297) "Very nice hotel" ![United States](https://a.travel-assets.com/egds/marks/flags/us.svg) Krist CA $168 CA $193 total includes taxes & fees Jan 5 - Jan 6, 2026 [](https://www.expedia.ca/San-Diego-Hotels-Hilton-Garden-Inn-San-Diego-Old-TownSeaWorld-Area.h919096.Hotel-Information) ![Exterior](https://images.trvl-media.com/lodging/1000000/10000/1500/1466/04fbf5a2.jpg?impolicy=fcrop&w=357&h=201&p=1&q=medium) ![Lobby](https://images.trvl-media.com/lodging/1000000/10000/1500/1466/0e02d545.jpg?impolicy=fcrop&w=357&h=201&p=1&q=medium) ![2 bars/lounges](https://images.trvl-media.com/lodging/1000000/10000/1500/1466/febc70a4.jpg?impolicy=fcrop&w=357&h=201&p=1&q=medium) ![2 bars/lounges](https://images.trvl-media.com/lodging/1000000/10000/1500/1466/a35bbd39.jpg?impolicy=fcrop&w=357&h=201&p=1&q=medium) ### San Diego Marriott Gaslamp Quarter [](https://www.expedia.ca/San-Diego-Hotels-San-Diego-Marriott-Gaslamp-Quarter.h1466.Hotel-Information) Downtown San Diego 8.6/10 Excellent (1595) "Clean room, comfortable beds. Good location and the staff was very friendly!!" ![United States](https://a.travel-assets.com/egds/marks/flags/us.svg) Linda CA $174 CA $202 total includes taxes & fees Dec 24 - Dec 25 [](https://www.expedia.ca/San-Diego-Hotels-San-Diego-Marriott-Gaslamp-Quarter.h1466.Hotel-Information) ![Dinner served, American cuisine](https://images.trvl-media.com/lodging/1000000/20000/11100/11026/b36144b8.jpg?impolicy=fcrop&w=357&h=201&p=1&q=medium) ![Front of property - evening/night](https://images.trvl-media.com/lodging/1000000/20000/11100/11026/5c8e191a.jpg?impolicy=fcrop&w=357&h=201&p=1&q=medium) ![Interior entrance](https://images.trvl-media.com/lodging/1000000/20000/11100/11026/93444558.jpg?impolicy=fcrop&w=357&h=201&p=1&q=medium) ![Interior entrance](https://images.trvl-media.com/lodging/1000000/20000/11100/11026/d9883b91.jpg?impolicy=fcrop&w=357&h=201&p=1&q=medium) ### The Horton Grand, Downtown/Gaslamp Quarter [](https://www.expedia.ca/San-Diego-Hotels-The-Horton-Grand.h11026.Hotel-Information) Downtown San Diego 9.0/10 Wonderful (2700) "Great place if you want to stay near glaslamp quarter district." ![Mexico](https://a.travel-assets.com/egds/marks/flags/mx.svg) Daniel CA $169 CA $234 total includes taxes & fees Dec 20 - Dec 21 [](https://www.expedia.ca/San-Diego-Hotels-The-Horton-Grand.h11026.Hotel-Information) ![Poolside bar](https://images.trvl-media.com/lodging/2000000/1740000/1731600/1731557/7e147d0f.jpg?impolicy=fcrop&w=357&h=201&p=1&q=medium) ![2 restaurants, breakfast served](https://images.trvl-media.com/lodging/2000000/1740000/1731600/1731557/6e7b1dc4.jpg?impolicy=fcrop&w=357&h=201&p=1&q=medium) ![2 restaurants, breakfast served](https://images.trvl-media.com/lodging/2000000/1740000/1731600/1731557/0fc52043.jpg?impolicy=fcrop&w=357&h=201&p=1&q=medium) ![Exterior](https://images.trvl-media.com/lodging/2000000/1740000/1731600/1731557/aa5f938d.jpg?impolicy=fcrop&w=357&h=201&p=1&q=medium) ### Hard Rock Hotel San Diego [](https://www.expedia.ca/San-Diego-Hotels-Hard-Rock-Hotel-San-Diego.h1731557.Hotel-Information) Downtown San Diego 9.0/10 Wonderful (3156) "Great stay" ![United States](https://a.travel-assets.com/egds/marks/flags/us.svg) Laurence CA $208 CA $305 total includes taxes & fees Jan 1 - Jan 2, 2026 [](https://www.expedia.ca/San-Diego-Hotels-Hard-Rock-Hotel-San-Diego.h1731557.Hotel-Information) Lowest nightly price found within the past 24 hours based on a 1 night stay for 2 adults. Prices and availability subject to change. Additional terms may apply. [View all properties](https://expedia.ca/Hotel-Search?startDate=2026-01-02&endDate=2026-01-03®ionId=6263723&adults=2&specialized_stays_group_explore=historic_property&sort=RECOMMENDED&openPlayBack=true) ## Top Otay Mesa Hotel Reviews ![Wyndham San Diego Bayside](https://images.trvl-media.com/lodging/1000000/20000/11200/11177/c44ff51d_y.jpg) ### Wyndham San Diego Bayside 10/10 Excellent "Fantastic location for catching a cruise. Right across the street!!! Great views as well! " [](https://expedia.ca/San-Diego-Hotels-Wyndham-San-Diego-Bayside.h11177.Hotel-Information) ![Best Western Plus Marina Gateway Hotel](https://images.trvl-media.com/lodging/3000000/2820000/2816700/2816688/f3777dfe_y.jpg) ### Best Western Plus Marina Gateway Hotel 10/10 Excellent "Nice room and beds" [](https://expedia.ca/National-City-Hotels-Best-Western-Plus-Marina-Gateway-Hotel.h2816688.Hotel-Information) ![Hard Rock Hotel San Diego](https://images.trvl-media.com/lodging/2000000/1740000/1731600/1731557/fbbdfc57_y.jpg) ### Hard Rock Hotel San Diego 10/10 Excellent "Clean. Great room " [](https://expedia.ca/San-Diego-Hotels-Hard-Rock-Hotel-San-Diego.h1731557.Hotel-Information) ![Marriott Marquis San Diego Marina](https://images.trvl-media.com/lodging/1000000/30000/24400/24394/9078a9ee_y.jpg) ### Marriott Marquis San Diego Marina 10/10 Excellent "Amazing stay. Absolutely perfect " [](https://expedia.ca/San-Diego-Hotels-Marriott-Marquis-San-Diego-Marina.h24394.Hotel-Information) ![Sheraton San Diego Resort](https://images.trvl-media.com/lodging/1000000/20000/11200/11109/w4000h2662x0y0-91d299a1_y.jpg) ### Sheraton San Diego Resort 10/10 Excellent "The hotel was clean, festive and helpful. Very accommodating. I will definitely come back. " [](https://expedia.ca/San-Diego-Hotels-Sheraton-San-Diego-Hotel-And-Marina.h11109.Hotel-Information) ![Pendry San Diego](https://images.trvl-media.com/lodging/17000000/16300000/16299000/16298963/05d0e601_y.jpg) ### Pendry San Diego 10/10 Excellent "Clean room staff gently " [](https://expedia.ca/San-Diego-Hotels-Pendry-San-Diego.h16298963.Hotel-Information) ![The DEXTRO Little Italy, BW Premier Collection](https://images.trvl-media.com/lodging/1000000/180000/170400/170338/6fe441dd_y.jpg) ### The DEXTRO Little Italy, BW Premier Collection 10/10 Excellent "It was great " [](https://expedia.ca/San-Diego-Hotels-Four-Points-By-Sheraton-San-Diego-Downtown-Little-Italy.h170338.Hotel-Information) ![Handlery Hotel](https://images.trvl-media.com/lodging/1000000/10000/8400/8374/ab6ccd55_y.jpg) ### Handlery Hotel 10/10 Excellent "Staff was friendly room was very clean " [](https://expedia.ca/San-Diego-Hotels-Handlery-Hotel.h8374.Hotel-Information) ![Courtyard by Marriott San Diego Downtown Little Italy](https://images.trvl-media.com/lodging/1000000/20000/13300/13205/db3040ff_y.jpg) ### Courtyard by Marriott San Diego Downtown Little Italy 10/10 Excellent "Clean rooms, friendly staff" [](https://expedia.ca/San-Diego-Hotels-The-Little-Italy-Hotel-In-Downtown-San-Diego.h13205.Hotel-Information) ## Frequently asked questions ### What can a history enthusiast expect from a trip to Otay Mesa? ### How many historical hotels will I find in Otay Mesa? ### What are the top historical places and other sights to visit in Otay Mesa? ### What is a historic hotel like in Otay Mesa? ### What is the difference between a historic hotel and a heritage hotel? ### Do historic hotels in Otay Mesa have modern facilities? ## Explore a world of travel with Expedia - 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