Title: Book the Best HISTORIC Hotels in Otay Mesa in 2025 | Expedia.ca [Vacation Rentals in San Diego](https://expedia.ca/San-Diego-Vacation-Rentals.d3073.Travel-Guide-VacationRentals)[Flights to San Diego](https://expedia.ca/Cheap-Flights-To-San-Diego.d3073.Travel-Guide-Flights)[Things to do in San Diego](https://expedia.ca/Things-To-Do-In-San-Diego.d3073.Travel-Guide-Activities)[Otay Mesa Car Rentals](https://expedia.ca/Car-Rentals-In-Otay-Mesa.d6263723.Car-Rental-Guide)[Otay Mesa Vacations](https://expedia.ca/Otay-Mesa.d6263723.Destination-Travel-Guides) ![Default HTG hotel image](https://media.expedia.com/media/content/shared/images/travelguides/sem-hotels-tablet.jpg?impolicy=fcrop&w=1200&h=500&q=medium) # Find Historic Hotels in Otay Mesa, CA from CA $112 ![](https://a.travel-assets.com/travel-assets-manager/pictogram-bex/light__calendar_shield.svg) ### Change your mind Book hotels with free cancellation ![](https://a.travel-assets.com/travel-assets-manager/pictogram-bex/light__deals.svg) ### Treat yourself Sign in to save 10% or more on thousands of hotels [Sign in](https://www.expedia.ca/login) ![](https://a.travel-assets.com/travel-assets-manager/pictogram-bex/light__bed.svg) ### Be picky Search almost a million properties worldwide ## Check availability on Otay Mesa Historic Hotels Tonight [Oct 15 - Oct 16](https://www.expedia.ca/Hotel-Search?regionId=6263723&startDate=2025-10-15&endDate=2025-10-16&adults=2&rfrr=TG.LP.CheckPrices.Hotel&openPlayBack=true) Tomorrow [Oct 16 - Oct 17](https://www.expedia.ca/Hotel-Search?regionId=6263723&startDate=2025-10-16&endDate=2025-10-17&adults=2&rfrr=TG.LP.CheckPrices.Hotel&openPlayBack=true) This weekend [Oct 17 - Oct 19](https://www.expedia.ca/Hotel-Search?regionId=6263723&startDate=2025-10-17&endDate=2025-10-19&adults=2&rfrr=TG.LP.CheckPrices.Hotel&openPlayBack=true) Next weekend [Oct 24 - Oct 26](https://www.expedia.ca/Hotel-Search?regionId=6263723&startDate=2025-10-24&endDate=2025-10-26&adults=2&rfrr=TG.LP.CheckPrices.Hotel&openPlayBack=true) ## Top Otay Mesa Historic Hotels ![Lobby](https://images.trvl-media.com/lodging/1000000/10000/5000/4926/5feb0059.jpg?impolicy=fcrop&w=357&h=201&p=1&q=medium) ![Desk, iron/ironing board, free cribs/infant beds, free WiFi](https://images.trvl-media.com/lodging/1000000/10000/5000/4926/7a33c92c.jpg?impolicy=fcrop&w=357&h=201&p=1&q=medium) ![Free daily on-the-go breakfast](https://images.trvl-media.com/lodging/1000000/10000/5000/4926/aeb717a4.jpg?impolicy=fcrop&w=357&h=201&p=1&q=medium) ![Room, 1 King Bed, Accessible, Non Smoking (Mobility/Hearing Impaired) | Bathroom](https://images.trvl-media.com/lodging/1000000/10000/5000/4926/a4925138.jpg?impolicy=fcrop&w=357&h=201&p=1&q=medium) ### Super 8 by Wyndham El Cajon/San Diego El Cajon 7.8/10 Good (1006) "Great place " CA $101 CA $112 total includes taxes & fees Oct 26 - Oct 27 [](https://www.expedia.ca/El-Cajon-Hotels-Super-8-By-Wyndham-El-Cajon-CA.h4926.Hotel-Information) ![Exterior](https://images.trvl-media.com/lodging/19000000/18970000/18961900/18961850/ac267ada.jpg?impolicy=fcrop&w=357&h=201&p=1&q=medium) ![Premium bedding, down comforters, pillowtop beds, desk](https://images.trvl-media.com/lodging/19000000/18970000/18961900/18961850/4faf4523.jpg?impolicy=fcrop&w=357&h=201&p=1&q=medium) ![Property amenity](https://images.trvl-media.com/lodging/19000000/18970000/18961900/18961850/782ee0d9.jpg?impolicy=fcrop&w=357&h=201&p=1&q=medium) ![Reception](https://images.trvl-media.com/lodging/19000000/18970000/18961900/18961850/d6f6a325.jpg?impolicy=fcrop&w=357&h=201&p=1&q=medium) ### Courtyard by Marriott San Diego El Cajon El Cajon 9.2/10 Wonderful (1005) "Very friendly staff, food was delicious." CA $195 CA $215 total includes taxes & fees Nov 2 - Nov 3 [](https://www.expedia.ca/El-Cajon-Hotels-Courtyard-By-Marriott-San-Diego-El-Cajon.h18961850.Hotel-Information) ![Standard Room, 2 Queen Beds](https://images.trvl-media.com/lodging/2000000/1610000/1606000/1605909/270b094d.jpg?impolicy=fcrop&w=357&h=201&p=1&q=medium) ![Check-in/check-out kiosk](https://images.trvl-media.com/lodging/2000000/1610000/1606000/1605909/c1eaeff1.jpg?impolicy=fcrop&w=357&h=201&p=1&q=medium) ![Desk, iron/ironing board, free WiFi, bed sheets](https://images.trvl-media.com/lodging/2000000/1610000/1606000/1605909/374ae34a.jpg?impolicy=fcrop&w=357&h=201&p=1&q=medium) ![Free self parking](https://images.trvl-media.com/lodging/2000000/1610000/1606000/1605909/a5127929.jpg?impolicy=fcrop&w=357&h=201&p=1&q=medium) ### Northgate Motel El Cajon 7.8/10 Good (633) "Clean room, efficient staff for checkin" CA $114 CA $126 total includes taxes & fees Oct 20 - Oct 21 [](https://www.expedia.ca/El-Cajon-Hotels-Northgate-Motel.h1605909.Hotel-Information) ![Property grounds](https://images.trvl-media.com/lodging/35000000/34150000/34142000/34141960/148582f5.jpg?impolicy=fcrop&w=357&h=201&p=1&q=medium) ![Interior](https://images.trvl-media.com/lodging/35000000/34150000/34142000/34141960/2473bb3f.jpg?impolicy=fcrop&w=357&h=201&p=1&q=medium) ![Fridge, microwave, oven, stovetop](https://images.trvl-media.com/lodging/35000000/34150000/34142000/34141960/e96e5cd6.jpg?impolicy=fcrop&w=357&h=201&p=1&q=medium) ![Desk, iron/ironing board, WiFi, bed sheets](https://images.trvl-media.com/lodging/35000000/34150000/34142000/34141960/96caf016.jpg?impolicy=fcrop&w=357&h=201&p=1&q=medium) ### Beautiful NEW One Bedroom Studio in San Diego (Mt. Helix) Mount Helix 10/10 Exceptional (4) "Cindy was and amazing host and answer my questions promptly. The studio is well equipped for quick meals and the bathroom is upscale. All the appointments and finishes are as advertised and would stay again." CA $188 CA $336 total includes taxes & fees Oct 19 - Oct 20 [](https://www.expedia.ca/La-Mesa-Hotels-Beautiful-NEW-One-Bedroom-Studio-In-San-Diego.h34141960.Hotel-Information) ![Exterior](https://images.trvl-media.com/lodging/3000000/2920000/2918200/2918129/a0a6825c.jpg?impolicy=fcrop&w=357&h=201&p=1&q=medium) ![Bar (on property)](https://images.trvl-media.com/lodging/3000000/2920000/2918200/2918129/49bcb235.jpg?impolicy=fcrop&w=357&h=201&p=1&q=medium) ![Outdoor pool](https://images.trvl-media.com/lodging/3000000/2920000/2918200/2918129/e3befa7e.jpg?impolicy=fcrop&w=357&h=201&p=1&q=medium) ![Bar (on property)](https://images.trvl-media.com/lodging/3000000/2920000/2918200/2918129/a9bcd444.jpg?impolicy=fcrop&w=357&h=201&p=1&q=medium) ### Residence Inn by Marriott San Diego Downtown/Gaslamp Quarter Downtown San Diego 9.0/10 Wonderful (1170) "Clean room ,friendly staff, great location " CA $182 CA $211 total includes taxes & fees Oct 20 - Oct 21 [](https://www.expedia.ca/San-Diego-Hotels-Residence-Inn-By-Marriott-San-Diego-DowntownGaslamp-Quarter.h2918129.Hotel-Information) ![View from property](https://images.trvl-media.com/lodging/28000000/27710000/27705700/27705643/d8379b79.jpg?impolicy=fcrop&w=357&h=201&p=1&q=medium) ![Restaurant](https://images.trvl-media.com/lodging/28000000/27710000/27705700/27705643/79521e2c.jpg?impolicy=fcrop&w=357&h=201&p=1&q=medium) ![Lobby lounge](https://images.trvl-media.com/lodging/28000000/27710000/27705700/27705643/3246a01d.jpg?impolicy=fcrop&w=357&h=201&p=1&q=medium) ![Daily full breakfast for a fee](https://images.trvl-media.com/lodging/28000000/27710000/27705700/27705643/81efe5fe.jpg?impolicy=fcrop&w=357&h=201&p=1&q=medium) ### Moxy San Diego Downtown/Gaslamp Quarter Downtown San Diego 9.0/10 Wonderful (1015) "Great area and great hotel " CA $178 CA $206 total includes taxes & fees Oct 20 - Oct 21 [](https://www.expedia.ca/San-Diego-Hotels-Moxy-San-Diego-DowntownGaslamp-Quarter.h27705643.Hotel-Information) ![Rooftop terrace](https://images.trvl-media.com/lodging/89000000/88400000/88398500/88398416/4480f6ef.jpg?impolicy=fcrop&w=357&h=201&p=1&q=medium) ![Lobby sitting area](https://images.trvl-media.com/lodging/89000000/88400000/88398500/88398416/881441d5.jpg?impolicy=fcrop&w=357&h=201&p=1&q=medium) ![Lobby sitting area](https://images.trvl-media.com/lodging/89000000/88400000/88398500/88398416/63587042.jpg?impolicy=fcrop&w=357&h=201&p=1&q=medium) ![Lobby](https://images.trvl-media.com/lodging/89000000/88400000/88398500/88398416/dd3cca67.jpg?impolicy=fcrop&w=357&h=201&p=1&q=medium) ### Palihotel San Diego Gaslamp Quarter Downtown San Diego 8.8/10 Excellent (1915) "Staff was great location was great" CA $158 CA $183 total includes taxes & fees Oct 20 - Oct 21 [](https://www.expedia.ca/San-Diego-Hotels-Palihotel-San-Diego.h88398416.Hotel-Information) ![Front of property](https://images.trvl-media.com/lodging/2000000/1580000/1573900/1573807/ba6cea84.jpg?impolicy=fcrop&w=357&h=201&p=1&q=medium) ![Lobby](https://images.trvl-media.com/lodging/2000000/1580000/1573900/1573807/75ec9582.jpg?impolicy=fcrop&w=357&h=201&p=1&q=medium) ![Premier Suite, 2 Double Beds, Roll-in Shower, City View](https://images.trvl-media.com/lodging/2000000/1580000/1573900/1573807/c0dfd2f9.jpg?impolicy=fcrop&w=357&h=201&p=1&q=medium) ![1 bedroom, premium bedding, pillowtop beds, in-room safe](https://images.trvl-media.com/lodging/2000000/1580000/1573900/1573807/f8b10da9.jpg?impolicy=fcrop&w=357&h=201&p=1&q=medium) ### The Sofia Hotel Downtown San Diego 8.4/10 Very good (1619) "I loved the stay here, highly recommended " CA $149 CA $206 total includes taxes & fees Oct 20 - Oct 21 [](https://www.expedia.ca/San-Diego-Hotels-The-Sofia-Hotel.h1573807.Hotel-Information) ![Premium bedding, pillowtop beds, desk, blackout drapes](https://images.trvl-media.com/lodging/12000000/11490000/11486100/11486063/c31e05e6.jpg?impolicy=fcrop&w=357&h=201&p=1&q=medium) ![Reception](https://images.trvl-media.com/lodging/12000000/11490000/11486100/11486063/1fbe17de.jpg?impolicy=fcrop&w=357&h=201&p=1&q=medium) ![Front of property - evening/night](https://images.trvl-media.com/lodging/12000000/11490000/11486100/11486063/53d75480.jpg?impolicy=fcrop&w=357&h=201&p=1&q=medium) ![Hallway](https://images.trvl-media.com/lodging/12000000/11490000/11486100/11486063/ec632047.jpg?impolicy=fcrop&w=357&h=201&p=1&q=medium) ### Staypineapple, Hotel Z, Gaslamp San Diego Downtown San Diego 9.4/10 Exceptional (1002) "Perfect location. " CA $192 CA $263 total includes taxes & fees Nov 2 - Nov 3 [](https://www.expedia.ca/San-Diego-Hotels-Staypineapple.h11486063.Hotel-Information) ![Exterior](https://images.trvl-media.com/lodging/1000000/20000/14800/14745/32781143.jpg?impolicy=fcrop&w=357&h=201&p=1&q=medium) ![Standard Room, 2 Queen Beds, Non Smoking](https://images.trvl-media.com/lodging/1000000/20000/14800/14745/5a1601df.jpg?impolicy=fcrop&w=357&h=201&p=1&q=medium) ![Lobby](https://images.trvl-media.com/lodging/1000000/20000/14800/14745/9fc7cd11.jpg?impolicy=fcrop&w=357&h=201&p=1&q=medium) ![Exterior](https://images.trvl-media.com/lodging/1000000/20000/14800/14745/ddc24aab.jpg?impolicy=fcrop&w=357&h=201&p=1&q=medium) ### Comfort Inn San Diego Old Town Old Town San Diego 8.0/10 Very good (1879) "Everything was nice, staff was very friendly, area was accommodating. All in all was an excellent stay. " CA $138 CA $158 total includes taxes & fees Oct 26 - Oct 27 [](https://www.expedia.ca/San-Diego-Hotels-Comfort-Inn-San-Diego-Old-Town.h14745.Hotel-Information) Lowest nightly price found within the past 24 hours based on a 1 night stay for 2 adults. Prices and availability subject to change. Additional terms may apply. [View all properties](https://expedia.ca/Hotel-Search?startDate=2025-10-30&endDate=2025-10-31®ionId=6263723&adults=2&specialized_stays_group_explore=historic_property&sort=RECOMMENDED&openPlayBack=true) ## Top Otay Mesa Hotel Reviews ![Hilton San Diego Mission Valley](//images.trvl-media.com/lodging/1000000/20000/16100/16019/w3839h2160x1y0-98566ca3_y.jpg) ### Hilton San Diego Mission Valley 10/10 Excellent "Clean rooms, nice staff etc.." [](https://expedia.ca/San-Diego-Hotels-Hilton-San-Diego-Mission-Valley.h16019.Hotel-Information) ![Wyndham Garden San Diego Near SeaWorld](//images.trvl-media.com/lodging/1000000/50000/41000/40962/76b78879_y.jpg) ### Wyndham Garden San Diego Near SeaWorld 10/10 Excellent "Staff was super friendly, room and propert was clean. Great experience!" [](https://expedia.ca/San-Diego-Hotels-Wyndham-Garden-San-Diego-Near-SeaWorld.h40962.Hotel-Information) ![Hard Rock Hotel San Diego](//images.trvl-media.com/lodging/2000000/1740000/1731600/1731557/fbbdfc57_y.jpg) ### Hard Rock Hotel San Diego 10/10 Excellent "Best place to stay for city center activities. Close to everything and hotel is well-appointed. " [](https://expedia.ca/San-Diego-Hotels-Hard-Rock-Hotel-San-Diego.h1731557.Hotel-Information) ![Sheraton San Diego Resort](//images.trvl-media.com/lodging/1000000/20000/11200/11109/w4000h2662x0y0-91d299a1_y.jpg) ### Sheraton San Diego Resort 10/10 Excellent "Love it here. We try to stay here every time we’re in SD " [](https://expedia.ca/San-Diego-Hotels-Sheraton-San-Diego-Hotel-And-Marina.h11109.Hotel-Information) ![The DEXTRO Little Italy, BW Premier Collection](//images.trvl-media.com/lodging/1000000/180000/170400/170338/84efd019_y.jpg) ### The DEXTRO Little Italy, BW Premier Collection 10/10 Excellent "I really liked this place, it is quiet, clean and is located in a nice place, the only think I didn't like is that I had to pay $35 to use the parking lot." [](https://expedia.ca/San-Diego-Hotels-Four-Points-By-Sheraton-San-Diego-Downtown-Little-Italy.h170338.Hotel-Information) ![Manchester Grand Hyatt San Diego](//images.trvl-media.com/lodging/1000000/20000/12100/12073/w3840h2092x0y3-447c77a4_y.jpg) ### Manchester Grand Hyatt San Diego 10/10 Excellent "Always great! Room and view were beautiful. Only thing was the hallway had bits of trash throughout. " [](https://expedia.ca/San-Diego-Hotels-Manchester-Grand-Hyatt-San-Diego.h12073.Hotel-Information) ![Best Western Plus Marina Gateway Hotel](//images.trvl-media.com/lodging/3000000/2820000/2816700/2816688/f3777dfe_y.jpg) ### Best Western Plus Marina Gateway Hotel 10/10 Excellent "The hotel is clean and relaxing. The staff is courteous and always eager to accommodate. The best part was the coffee machine in the lobby. I'll be returning. " [](https://expedia.ca/National-City-Hotels-Best-Western-Plus-Marina-Gateway-Hotel.h2816688.Hotel-Information) ![Wyndham San Diego Bayside](//images.trvl-media.com/lodging/1000000/20000/11200/11177/c44ff51d_y.jpg) ### Wyndham San Diego Bayside 10/10 Excellent "Great that there is an airport shuttle. Very convenient to cruise terminal." [](https://expedia.ca/San-Diego-Hotels-Wyndham-San-Diego-Bayside.h11177.Hotel-Information) ![The Dana on Mission Bay](//images.trvl-media.com/lodging/1000000/50000/41000/40953/08585098_y.jpg) ### The Dana on Mission Bay 10/10 Excellent "Staff is awesome" [](https://expedia.ca/San-Diego-Hotels-The-Dana-On-Mission-Bay.h40953.Hotel-Information) ## Frequently asked questions ### What can a history enthusiast expect from a trip to Otay Mesa? > A visit to the historical sites in Otay Mesa is likely on top of your sightseeing itinerary. While you're here, you can visit the shops and beaches. During your stay in this family-friendly area, you can also relish a trip to the restaurants. ### How many historical hotels will I find in Otay Mesa? > In Otay Mesa, you'll find 2 hotels and other accommodations bookable on Expedia though not many historic hotels to choose from. ### What are the top historical places and other sights to visit in Otay Mesa? > San Diego Zoo, San Ysidro Border Crossing, and Hotel del Coronado are some of the notable places to visit in the surrounding area. In the area, you'll also find Petco Park and USS Midway Museum. ### What is a historic hotel like in Otay Mesa? > Guests who choose historic hotels have the opportunity to stay in a building officially recognized with a historic designation. Historic hotels throughout the world can take the form of castles, palaces, grand homes or even old police stations, pubs, lodges or skyscrapers. These types of hotels in Otay Mesa typically preserve authentic elements such as period features or traditional architecture in guestrooms or communal spaces. ### What is the difference between a historic hotel and a heritage hotel? > You'll often hear the term "heritage hotel" in Asia and Europe, while "historic hotel" is more common in the U.S. overall though the terms are similar. The architecture and building of historic hotels are generally what's most important. For a heritage hotel, mainly, it's cultural value along with how it shaped the community. ### Do historic hotels in Otay Mesa have modern facilities? > Hotels include modern conveniences and safety features you expect to find, but every effort is made to preserve historic facades and treasured traditions. WiFi, heating and air conditioning, updated bathroom facilities, and the amenities found at a contemporary hotel should be available at a historic hotel. Rest assured that when you choose a historic hotel in Otay Mesa, you won't find yourself staying at a place that's uncomfortable or rundown. ## Explore a world of travel with Expedia - Lodging - More ways to book - [Beach Hotel Hotels in Camp Pendleton Marine Corps Base](https://www.expedia.ca/Camp-Pendleton-Marine-Corps-Base-Hotels-Beach-Hotel.0-0-d6068523-tBeachHotel.Travel-Guide-Filter-Hotels) - [Hotels with Early Check-in in Camp Pendleton Marine Corps Base](https://www.expedia.ca/Camp-Pendleton-Marine-Corps-Base-Hotels-Hotel-With-Early-Check-In.0-0-d6068523-thotelwithearlycheckin.Travel-Guide-Filter-Hotels) - [Hotels with an Indoor Pool in Camp Pendleton Marine Corps Base](https://www.expedia.ca/Camp-Pendleton-Marine-Corps-Base-Hotels-Hotels-With-Indoor-Pool.0-0-d6068523-tHotelswithIndoorPool.Travel-Guide-Filter-Hotels) - [Luxury Hotels in Camp Pendleton Marine Corps Base](https://www.expedia.ca/Camp-Pendleton-Marine-Corps-Base-Hotels-Luxury-Hotel.0-0-d6068523-tLuxuryHotel.Travel-Guide-Filter-Hotels) - 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