Title: Book the Best Otay Mesa CASINO Hotels & Resorts in 2025 | Expedia.ca [Vacation Rentals in San Diego](https://expedia.ca/San-Diego-Vacation-Rentals.d3073.Travel-Guide-VacationRentals)[Flights to San Diego](https://expedia.ca/Cheap-Flights-To-San-Diego.d3073.Travel-Guide-Flights)[Things to do in San Diego](https://expedia.ca/Things-To-Do-In-San-Diego.d3073.Travel-Guide-Activities)[Otay Mesa Car Rentals](https://expedia.ca/Car-Rentals-In-Otay-Mesa.d6263723.Car-Rental-Guide)[Otay Mesa Vacations](https://expedia.ca/Otay-Mesa.d6263723.Destination-Travel-Guides) ![Default HTG hotel image](https://a.travel-assets.com/travel-assets-manager/fallback-images-brand/bex_lodging_v2.jpg?impolicy=fcrop&w=1200&h=500&q=medium) # Find Casino Hotels in Otay Mesa, CA from CA $101 ![](https://a.travel-assets.com/travel-assets-manager/pictogram-bex/light__calendar_shield.svg) ### Change your mind Book hotels with free cancellation ![](https://a.travel-assets.com/travel-assets-manager/pictogram-bex/light__deals.svg) ### Treat yourself Sign in to save 10% or more on thousands of hotels [Sign in](https://www.expedia.ca/login) ![](https://a.travel-assets.com/travel-assets-manager/pictogram-bex/light__bed.svg) ### Be picky Search almost a million properties worldwide ## Check availability on Otay Mesa Casino Hotels Tonight [Oct 13 - Oct 14](https://www.expedia.ca/Hotel-Search?regionId=6263723&startDate=2025-10-13&endDate=2025-10-14&adults=2&amenities=CASINO&rfrr=TG.LP.CheckPrices.Hotel&openPlayBack=true) Tomorrow [Oct 14 - Oct 15](https://www.expedia.ca/Hotel-Search?regionId=6263723&startDate=2025-10-14&endDate=2025-10-15&adults=2&amenities=CASINO&rfrr=TG.LP.CheckPrices.Hotel&openPlayBack=true) This weekend [Oct 17 - Oct 19](https://www.expedia.ca/Hotel-Search?regionId=6263723&startDate=2025-10-17&endDate=2025-10-19&adults=2&amenities=CASINO&rfrr=TG.LP.CheckPrices.Hotel&openPlayBack=true) Next weekend [Oct 24 - Oct 26](https://www.expedia.ca/Hotel-Search?regionId=6263723&startDate=2025-10-24&endDate=2025-10-26&adults=2&amenities=CASINO&rfrr=TG.LP.CheckPrices.Hotel&openPlayBack=true) ## Top Otay Mesa Casino Hotels ![Terrace/patio](https://images.trvl-media.com/lodging/50000000/49290000/49284700/49284697/w3836h2556x3y3-467b2b48.jpg?impolicy=fcrop&w=357&h=201&p=1&q=medium) ![In-room safe, desk, blackout drapes, iron/ironing board](https://images.trvl-media.com/lodging/50000000/49290000/49284700/49284697/w3840h2558x0y3-98d4fb1d.jpg?impolicy=fcrop&w=357&h=201&p=1&q=medium) ![Free daily buffet breakfast](https://images.trvl-media.com/lodging/50000000/49290000/49284700/49284697/720d452f.jpg?impolicy=fcrop&w=357&h=201&p=1&q=medium) ![Lobby](https://images.trvl-media.com/lodging/50000000/49290000/49284700/49284697/w3839h2555x0y3-5f9fe6e4.jpg?impolicy=fcrop&w=357&h=201&p=1&q=medium) ### Hampton Inn & Suites Imperial Beach San Diego Imperial Beach 9.4/10 Exceptional (905) "Really nice place to stay!" CA $171 CA $195 total includes taxes & fees Oct 19 - Oct 20 [](https://www.expedia.ca/Imperial-Beach-Hotels-Hampton-Inn-Suites-Imperial-Beach-San-Diego.h49284697.Hotel-Information) ![3 outdoor pools, cabanas (surcharge), pool umbrellas](https://images.trvl-media.com/lodging/34000000/33670000/33661500/33661441/1f4c359a.jpg?impolicy=fcrop&w=357&h=201&p=1&q=medium) ![7 restaurants, breakfast served](https://images.trvl-media.com/lodging/34000000/33670000/33661500/33661441/7910f1d4.jpg?impolicy=fcrop&w=357&h=201&p=1&q=medium) ![Property grounds](https://images.trvl-media.com/lodging/34000000/33670000/33661500/33661441/91cdc1c7.jpg?impolicy=fcrop&w=357&h=201&p=1&q=medium) ![7 restaurants, breakfast served](https://images.trvl-media.com/lodging/34000000/33670000/33661500/33661441/250333ae.jpg?impolicy=fcrop&w=357&h=201&p=1&q=medium) ### Sycuan Casino Resort El Cajon 9.2/10 Wonderful (1571) "Great resort!" CA $150 CA $182 total includes taxes & fees Nov 4 - Nov 5 [](https://www.expedia.ca/El-Cajon-Hotels-Sycuan-Casino-Resort.h33661441.Hotel-Information) ![Outdoor pool, open 9:00 AM to 9:00 PM, pool umbrellas, sun loungers](https://images.trvl-media.com/lodging/1000000/1000000/996200/996144/a653b43a.jpg?impolicy=fcrop&w=357&h=201&p=1&q=medium) ![Lobby](https://images.trvl-media.com/lodging/1000000/1000000/996200/996144/63e66623.jpg?impolicy=fcrop&w=357&h=201&p=1&q=medium) ![Blackout drapes, iron/ironing board, free WiFi, bed sheets](https://images.trvl-media.com/lodging/1000000/1000000/996200/996144/6a0c40cf.jpg?impolicy=fcrop&w=357&h=201&p=1&q=medium) ![Vending machine](https://images.trvl-media.com/lodging/1000000/1000000/996200/996144/6af9aa5a.jpg?impolicy=fcrop&w=357&h=201&p=1&q=medium) ### Motel 6 El Cajon, CA - San Diego El Cajon 7.2/10 Good (1401) "Great rooms for price " CA $92 CA $101 total includes taxes & fees Oct 14 - Oct 15 [](https://www.expedia.ca/El-Cajon-Hotels-Motel-6-El-Cajon.h996144.Hotel-Information) ![View from room](https://images.trvl-media.com/lodging/1000000/20000/18300/18213/b70d99f9.jpg?impolicy=fcrop&w=357&h=201&p=1&q=medium) ![1 bedroom, memory foam beds, desk, laptop workspace](https://images.trvl-media.com/lodging/1000000/20000/18300/18213/e0c0af28.jpg?impolicy=fcrop&w=357&h=201&p=1&q=medium) ![Business centre](https://images.trvl-media.com/lodging/1000000/20000/18300/18213/0df0eb3e.jpg?impolicy=fcrop&w=357&h=201&p=1&q=medium) ![Coffee shop](https://images.trvl-media.com/lodging/1000000/20000/18300/18213/41516864.jpg?impolicy=fcrop&w=357&h=201&p=1&q=medium) ### The Rambler Chula Vista 9.0/10 Wonderful (1974) "Staff was amazing, room was clean and the area is both quiet and accessible to the rest of the city. Would absolutely stay again!" CA $139 CA $160 total includes taxes & fees Oct 26 - Oct 27 [](https://www.expedia.ca/Chula-Vista-Hotels-The-Rambler-Motel.h18213.Hotel-Information) ![Breakfast and dinner served](https://images.trvl-media.com/lodging/2000000/1990000/1987700/1987617/43ae1d02.jpg?impolicy=fcrop&w=357&h=201&p=1&q=medium) ![Premium bedding, down comforters, desk, blackout drapes](https://images.trvl-media.com/lodging/2000000/1990000/1987700/1987617/486f9d1f.jpg?impolicy=fcrop&w=357&h=201&p=1&q=medium) ![Front of property](https://images.trvl-media.com/lodging/2000000/1990000/1987700/1987617/6248eb98.jpg?impolicy=fcrop&w=357&h=201&p=1&q=medium) ![Room, 1 King Bed with Sofa bed, Non Smoking](https://images.trvl-media.com/lodging/2000000/1990000/1987700/1987617/05adb83a.jpg?impolicy=fcrop&w=357&h=201&p=1&q=medium) ### Courtyard by Marriott San Diego Mission Valley/Hotel Circle Mission Valley 8.4/10 Very good (1375) "Great place to stay" CA $156 CA $179 total includes taxes & fees Oct 26 - Oct 27 [](https://www.expedia.ca/San-Diego-Hotels-Courtyard-By-Marriott-San-Diego-Mission-ValleyHotel-Circle.h1987617.Hotel-Information) ![Restaurant](https://images.trvl-media.com/lodging/11000000/10660000/10658600/10658517/d25452c4.jpg?impolicy=fcrop&w=357&h=201&p=1&q=medium) ![Design Studio Suite, 1 Bedroom, Accessible, Kitchenette](https://images.trvl-media.com/lodging/11000000/10660000/10658600/10658517/73e61621.jpg?impolicy=fcrop&w=357&h=201&p=1&q=medium) ![Outdoor pool, open 8:00 AM to 10:00 PM, sun loungers](https://images.trvl-media.com/lodging/11000000/10660000/10658600/10658517/06f8d9ca.jpg?impolicy=fcrop&w=357&h=201&p=1&q=medium) ![Lobby](https://images.trvl-media.com/lodging/11000000/10660000/10658600/10658517/df71d41d.jpg?impolicy=fcrop&w=357&h=201&p=1&q=medium) ### Crown City Inn Coronado 9.6/10 Exceptional (603) "Great stay! " CA $174 CA $192 total includes taxes & fees Oct 14 - Oct 15 [](https://www.expedia.ca/Coronado-Hotels-Crown-City-Inn.h10658517.Hotel-Information) ![Suite, 2 Queen Beds, Non Smoking, Refrigerator (with Sofabed)](https://images.trvl-media.com/lodging/3000000/2820000/2816700/2816688/f3777dfe.jpg?impolicy=fcrop&w=357&h=201&p=1&q=medium) ![Daily cooked-to-order breakfast for a fee](https://images.trvl-media.com/lodging/3000000/2820000/2816700/2816688/8bb8fc35.jpg?impolicy=fcrop&w=357&h=201&p=1&q=medium) ![Outdoor pool, open 9:00 AM to 10:00 PM, pool umbrellas, sun loungers](https://images.trvl-media.com/lodging/3000000/2820000/2816700/2816688/ade03197.jpg?impolicy=fcrop&w=357&h=201&p=1&q=medium) ![Bar (on property)](https://images.trvl-media.com/lodging/3000000/2820000/2816700/2816688/91baa1e7.jpg?impolicy=fcrop&w=357&h=201&p=1&q=medium) ### Best Western Plus Marina Gateway Hotel National City 9.2/10 Wonderful (3330) "Nice place to stay !" CA $188 CA $207 total includes taxes & fees Nov 2 - Nov 3 [](https://www.expedia.ca/National-City-Hotels-Best-Western-Plus-Marina-Gateway-Hotel.h2816688.Hotel-Information) ![Desk, blackout drapes, iron/ironing board, free WiFi](https://images.trvl-media.com/lodging/2000000/1800000/1798100/1798071/a90f2d6f.jpg?impolicy=fcrop&w=357&h=201&p=1&q=medium) ![Outdoor pool](https://images.trvl-media.com/lodging/2000000/1800000/1798100/1798071/d8ecd896.jpg?impolicy=fcrop&w=357&h=201&p=1&q=medium) ![Reception](https://images.trvl-media.com/lodging/2000000/1800000/1798100/1798071/58b6effd.jpg?impolicy=fcrop&w=357&h=201&p=1&q=medium) ![Vending machine](https://images.trvl-media.com/lodging/2000000/1800000/1798100/1798071/14f93e35.jpg?impolicy=fcrop&w=357&h=201&p=1&q=medium) ### Studio 6 Suites San Ysidro, CA -San Diego South Bay San Ysidro 7.8/10 Good (1299) "Ideally located " CA $97 CA $110 total includes taxes & fees Oct 14 - Oct 15 [](https://www.expedia.ca/San-Ysidro-Hotels-Studio-6-Suites-San-Ysidro.h1798071.Hotel-Information) ![Exterior](https://images.trvl-media.com/lodging/19000000/18970000/18961900/18961850/ac267ada.jpg?impolicy=fcrop&w=357&h=201&p=1&q=medium) ![Reception](https://images.trvl-media.com/lodging/19000000/18970000/18961900/18961850/d6f6a325.jpg?impolicy=fcrop&w=357&h=201&p=1&q=medium) ![Premium bedding, down comforters, pillowtop beds, desk](https://images.trvl-media.com/lodging/19000000/18970000/18961900/18961850/4faf4523.jpg?impolicy=fcrop&w=357&h=201&p=1&q=medium) ![Property amenity](https://images.trvl-media.com/lodging/19000000/18970000/18961900/18961850/782ee0d9.jpg?impolicy=fcrop&w=357&h=201&p=1&q=medium) ### Courtyard by Marriott San Diego El Cajon El Cajon 9.2/10 Wonderful (1004) "Excelente Hotel" CA $194 CA $214 total includes taxes & fees Nov 2 - Nov 3 [](https://www.expedia.ca/El-Cajon-Hotels-Courtyard-By-Marriott-San-Diego-El-Cajon.h18961850.Hotel-Information) ![Terrace/patio](https://images.trvl-media.com/lodging/112000000/111960000/111958400/111958344/fe94f9f3.jpg?impolicy=fcrop&w=357&h=201&p=1&q=medium) ![Lobby sitting area](https://images.trvl-media.com/lodging/112000000/111960000/111958400/111958344/2b448002.jpg?impolicy=fcrop&w=357&h=201&p=1&q=medium) ![Breakfast, lunch, dinner served; American cuisine, ocean views ](https://images.trvl-media.com/lodging/112000000/111960000/111958400/111958344/889d28b5.jpg?impolicy=fcrop&w=357&h=201&p=1&q=medium) ![Front of property](https://images.trvl-media.com/lodging/112000000/111960000/111958400/111958344/178c1eb8.jpg?impolicy=fcrop&w=357&h=201&p=1&q=medium) ### The Bower Coronado Historic Downtown Coronado 9.2/10 Wonderful (115) "Great hotel " CA $373 CA $481 total includes taxes & fees Nov 2 - Nov 3 [](https://www.expedia.ca/Coronado-Hotels-The-Bower.h111958344.Hotel-Information) Lowest nightly price found within the past 24 hours based on a 1 night stay for 2 adults. Prices and availability subject to change. Additional terms may apply. [View all properties](https://expedia.ca/Hotel-Search?startDate=2025-10-27&endDate=2025-10-28®ionId=6263723&adults=2&amenities=CASINO&sort=RECOMMENDED&openPlayBack=true) ## Top Otay Mesa Hotel Reviews ![Wyndham Garden San Diego Near SeaWorld](//images.trvl-media.com/lodging/1000000/50000/41000/40962/76b78879_y.jpg) ### Wyndham Garden San Diego Near SeaWorld 10/10 Excellent "Staff was super friendly, room and propert was clean. Great experience!" [](https://expedia.ca/San-Diego-Hotels-Wyndham-Garden-San-Diego-Near-SeaWorld.h40962.Hotel-Information) ![Days Inn by Wyndham San Diego Hotel Circle](//images.trvl-media.com/lodging/1000000/20000/19300/19220/3334d773_y.jpg) ### Days Inn by Wyndham San Diego Hotel Circle 10/10 Excellent "Location, price amazing! Friendly staff" [](https://expedia.ca/San-Diego-Hotels-Days-Inn-By-Wyndham-San-Diego-Hotel-Circle.h19220.Hotel-Information) ## Frequently asked questions ### Searching for casino hotels in Otay Mesa? > Hoping to win big in Otay Mesa? Lucky for you, you'll find Jamul Casino, Caliente Casino, and Caliente Racetrack Casino in the area, plus lots more to see and do. Visitors enjoy the family-friendly activities, beaches, and shopping. You might be interested in the area's popular sights, which include San Diego Zoo, San Ysidro Border Crossing, and Hotel del Coronado. ### What is there to do in Otay Mesa? > You can head to Alameda Otay, Plaza Península Shopping Center, or Plaza Rio Commercial Center to shop for the perfect souvenir. For a chance to experience some culture, you can check out North Island Credit Union Amphitheatre, Centro Cultural Tijuana, or Fronton Jai Alai Palace. 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