Title: Book the Best BUSINESS Hotels in Osage in 2026 | Expedia.ca [Hotels in Osage](https://expedia.ca/Osage-Hotels.d6024275.Travel-Guide-Hotels)[Vacation Rentals in Osage](https://expedia.ca/Osage-Vacation-Rentals.d6024275.Travel-Guide-VacationRentals)[Osage Car Rentals](https://expedia.ca/Car-Rentals-In-Osage.d6024275.Car-Rental-Guide)[Osage Vacation Packages](https://expedia.ca/Osage.d6024275.Destination-Travel-Guides) ![Default HTG hotel image](https://a.travel-assets.com/travel-assets-manager/bex-affinities/business.jpg?impolicy=fcrop&w=1200&h=500&q=medium) # Find Business Hotels in Osage, IA from CA $81 - ![](https://a.travel-assets.com/travel-assets-manager/pictogram-bex/light__calendar_shield.svg) ### Change your mind Book hotels with free cancellation - ![](https://a.travel-assets.com/travel-assets-manager/pictogram-bex/light__deals.svg) ### Treat yourself Sign in to save 10% or more on thousands of hotels [Sign in](https://www.expedia.ca/login) - ![](https://a.travel-assets.com/travel-assets-manager/pictogram-bex/light__bed.svg) ### Be picky Search almost a million properties worldwide ## Check availability on Osage Business Hotels Tonight [Dec 9 - Dec 10](https://www.expedia.ca/Hotel-Search?regionId=6024275&startDate=2025-12-09&endDate=2025-12-10&adults=2&rfrr=TG.LP.CheckPrices.Hotel&openPlayBack=true&travelerType=business_friendly) Tomorrow [Dec 10 - Dec 11](https://www.expedia.ca/Hotel-Search?regionId=6024275&startDate=2025-12-10&endDate=2025-12-11&adults=2&rfrr=TG.LP.CheckPrices.Hotel&openPlayBack=true&travelerType=business_friendly) This weekend [Dec 12 - Dec 14](https://www.expedia.ca/Hotel-Search?regionId=6024275&startDate=2025-12-12&endDate=2025-12-14&adults=2&rfrr=TG.LP.CheckPrices.Hotel&openPlayBack=true&travelerType=business_friendly) Next weekend [Dec 19 - Dec 21](https://www.expedia.ca/Hotel-Search?regionId=6024275&startDate=2025-12-19&endDate=2025-12-21&adults=2&rfrr=TG.LP.CheckPrices.Hotel&openPlayBack=true&travelerType=business_friendly) ## Our top choices for Osage business-friendly hotels ![Front of property - evening/night](https://images.trvl-media.com/lodging/6000000/5030000/5027500/5027430/1e38176f.jpg?impolicy=fcrop&w=357&h=201&p=1&q=medium) ![Indoor pool](https://images.trvl-media.com/lodging/6000000/5030000/5027500/5027430/860f0d5f.jpg?impolicy=fcrop&w=357&h=201&p=1&q=medium) ![Desk, laptop workspace, blackout drapes, iron/ironing board](https://images.trvl-media.com/lodging/6000000/5030000/5027500/5027430/0340a3c3.jpg?impolicy=fcrop&w=357&h=201&p=1&q=medium) ![Lobby](https://images.trvl-media.com/lodging/6000000/5030000/5027500/5027430/90a5456a.jpg?impolicy=fcrop&w=357&h=201&p=1&q=medium) ### AmericInn by Wyndham Osage Osage 9.6/10 Exceptional (271) "A good place to stay" ![United States](https://a.travel-assets.com/egds/marks/flags/us.svg) michael CA $126 CA $141 total includes taxes & fees Dec 28 - Dec 29 [](https://www.expedia.ca/Mason-City-Hotels-AmericInn-By-Wyndham-Osage.h5027430.Hotel-Information) ![Exterior](https://images.trvl-media.com/lodging/1000000/530000/523200/523133/9e1ed185.jpg?impolicy=fcrop&w=357&h=201&p=1&q=medium) ![In-room safe, desk, iron/ironing board, free cribs/infant beds](https://images.trvl-media.com/lodging/1000000/530000/523200/523133/823be9f9.jpg?impolicy=fcrop&w=357&h=201&p=1&q=medium) ![Lobby](https://images.trvl-media.com/lodging/1000000/530000/523200/523133/840c2132.jpg?impolicy=fcrop&w=357&h=201&p=1&q=medium) ![In-room safe, desk, iron/ironing board, free cribs/infant beds](https://images.trvl-media.com/lodging/1000000/530000/523200/523133/c5a53e24.jpg?impolicy=fcrop&w=357&h=201&p=1&q=medium) ### Microtel Inn & Suites By Wyndham Clear Lake Clear Lake 8.4/10 Very good (1002) "Nice hotel for the cost. " ![United States](https://a.travel-assets.com/egds/marks/flags/us.svg) Sean CA $82 CA $92 total includes taxes & fees Dec 24 - Dec 25 [](https://www.expedia.ca/Mason-City-Hotels-Microtel-Inn-Suites-By-Wyndham-Clear-Lake.h523133.Hotel-Information) ![Exterior](https://images.trvl-media.com/lodging/5000000/4150000/4141200/4141196/b9ec7d0e.jpg?impolicy=fcrop&w=357&h=201&p=1&q=medium) ![Free buffet breakfast](https://images.trvl-media.com/lodging/5000000/4150000/4141200/4141196/4272c59a.jpg?impolicy=fcrop&w=357&h=201&p=1&q=medium) ![Egyptian cotton sheets, in-room safe, desk, blackout drapes](https://images.trvl-media.com/lodging/5000000/4150000/4141200/4141196/eec65be3.jpg?impolicy=fcrop&w=357&h=201&p=1&q=medium) ![Indoor pool](https://images.trvl-media.com/lodging/5000000/4150000/4141200/4141196/454eefc3.jpg?impolicy=fcrop&w=357&h=201&p=1&q=medium) ### Holiday Inn Express Hotel & Suites Northwood by IHG Northwood 8.4/10 Very good (388) "Hotel was very clean Beautiful room great variety for breakfast " ![United States](https://a.travel-assets.com/egds/marks/flags/us.svg) Diane CA $135 CA $152 total includes taxes & fees Dec 26 - Dec 27 [](https://www.expedia.ca/Mason-City-Hotels-Holiday-Inn-Express-Hotel-Suites-Northwood.h4141196.Hotel-Information) ![Free daily buffet breakfast](https://images.trvl-media.com/lodging/1000000/660000/658100/658042/4b3ca419.jpg?impolicy=fcrop&w=357&h=201&p=1&q=medium) ![Room, 1 King Bed, Non Smoking](https://images.trvl-media.com/lodging/1000000/660000/658100/658042/bd8e6aee.jpg?impolicy=fcrop&w=357&h=201&p=1&q=medium) ![Lobby](https://images.trvl-media.com/lodging/1000000/660000/658100/658042/a8e22221.jpg?impolicy=fcrop&w=357&h=201&p=1&q=medium) ![Front of property - evening/night](https://images.trvl-media.com/lodging/1000000/660000/658100/658042/0482e45b.jpg?impolicy=fcrop&w=357&h=201&p=1&q=medium) ### AmericInn by Wyndham Clear Lake Clear Lake 9.0/10 Wonderful (1002) "Friendly staff, nice breakfast." ![United States](https://a.travel-assets.com/egds/marks/flags/us.svg) Marcia CA $105 CA $117 total includes taxes & fees Dec 21 - Dec 22 [](https://www.expedia.ca/Mason-City-Hotels-AmericInn-By-Wyndham-Clear-Lake.h658042.Hotel-Information) ![Desk, laptop workspace, iron/ironing board, free WiFi](https://images.trvl-media.com/lodging/1000000/970000/967500/967401/8c20615d.jpg?impolicy=fcrop&w=357&h=201&p=1&q=medium) ![Lobby](https://images.trvl-media.com/lodging/1000000/970000/967500/967401/71c7b2a2.jpg?impolicy=fcrop&w=357&h=201&p=1&q=medium) ![Desk, laptop workspace, iron/ironing board, free WiFi](https://images.trvl-media.com/lodging/1000000/970000/967500/967401/326b9c61.jpg?impolicy=fcrop&w=357&h=201&p=1&q=medium) ![Free continental breakfast](https://images.trvl-media.com/lodging/1000000/970000/967500/967401/85eaee11.jpg?impolicy=fcrop&w=357&h=201&p=1&q=medium) ### Sleep Inn & Suites Charles City Charles City 8.8/10 Excellent (282) "clean rooms, great staff, good breakfast" ![United States](https://a.travel-assets.com/egds/marks/flags/us.svg) Donna CA $126 CA $141 total includes taxes & fees Jan 4 - Jan 5, 2026 [](https://www.expedia.ca/Mason-City-Hotels-Sleep-Inn-Suites.h967401.Hotel-Information) ![Exterior](https://images.trvl-media.com/lodging/2000000/1590000/1580600/1580597/f073330b.jpg?impolicy=fcrop&w=357&h=201&p=1&q=medium) ![Premium bedding, desk, blackout drapes, soundproofing](https://images.trvl-media.com/lodging/2000000/1590000/1580600/1580597/3e508ec0.jpg?impolicy=fcrop&w=357&h=201&p=1&q=medium) ![Lobby](https://images.trvl-media.com/lodging/2000000/1590000/1580600/1580597/f92883cf.jpg?impolicy=fcrop&w=357&h=201&p=1&q=medium) ![Combined shower/tub, free toiletries, hair dryer, towels](https://images.trvl-media.com/lodging/2000000/1590000/1580600/1580597/7678811d.jpg?impolicy=fcrop&w=357&h=201&p=1&q=medium) ### Diamond Jo Worth Casino Hotel Northwood 8.6/10 Excellent (620) "love that it is connected to casino, very clean, reasonable pricing, great free breakfast " ![United States](https://a.travel-assets.com/egds/marks/flags/us.svg) ERIC CA $154 CA $172 total includes taxes & fees Dec 28 - Dec 29 [](https://www.expedia.ca/Northwood-Hotels-Country-Inn-Suites-By-Radisson.h1580597.Hotel-Information) ![Lobby](https://images.trvl-media.com/lodging/9000000/8700000/8693200/8693198/e4bb12a3.jpg?impolicy=fcrop&w=357&h=201&p=1&q=medium) ![Desk, iron/ironing board, free cribs/infant beds, bed sheets](https://images.trvl-media.com/lodging/9000000/8700000/8693200/8693198/48fd6d09.jpg?impolicy=fcrop&w=357&h=201&p=1&q=medium) ![Business centre](https://images.trvl-media.com/lodging/9000000/8700000/8693200/8693198/d0fbd9e3.jpg?impolicy=fcrop&w=357&h=201&p=1&q=medium) ![Exterior](https://images.trvl-media.com/lodging/9000000/8700000/8693200/8693198/45cce4e2.jpg?impolicy=fcrop&w=357&h=201&p=1&q=medium) ### Americas Best Value Inn Clear Lake Clear Lake 7.0/10 Good (853) "Clean room, easy check in" ![United States](https://a.travel-assets.com/egds/marks/flags/us.svg) Evelyn CA $82 CA $92 total includes taxes & fees Dec 27 - Dec 28 [](https://www.expedia.ca/Mason-City-Hotels-Americas-Best-Value-Inn-Clear-Lake.h8693198.Hotel-Information) ![Front of property](https://images.trvl-media.com/lodging/1000000/900000/894500/894408/2ad1a7f4.jpg?impolicy=fcrop&w=357&h=201&p=1&q=medium) ![Desk, laptop workspace, blackout drapes, iron/ironing board](https://images.trvl-media.com/lodging/1000000/900000/894500/894408/c059335b.jpg?impolicy=fcrop&w=357&h=201&p=1&q=medium) ![Lobby](https://images.trvl-media.com/lodging/1000000/900000/894500/894408/f39609bd.jpg?impolicy=fcrop&w=357&h=201&p=1&q=medium) ![Desk, laptop workspace, blackout drapes, iron/ironing board](https://images.trvl-media.com/lodging/1000000/900000/894500/894408/0ff28aa6.jpg?impolicy=fcrop&w=357&h=201&p=1&q=medium) ### Country Inn & Suites by Radisson, Mason City, IA Mason City 8.4/10 Very good (591) "Comfortable spacious queit room, breakfast selection was good, clean family style pool and older hot tub to relax in after long drive. We would stay again. " ![United States](https://a.travel-assets.com/egds/marks/flags/us.svg) Heather CA $157 CA $176 total includes taxes & fees Jan 4 - Jan 5, 2026 [](https://www.expedia.ca/Mason-City-Hotels-Country-Inn-Suites-By-Radisson.h894408.Hotel-Information) ![Lobby](https://images.trvl-media.com/lodging/4000000/3060000/3052600/3052573/4e051bf1.jpg?impolicy=fcrop&w=357&h=201&p=1&q=medium) ![Individually decorated, individually furnished, desk, iron/ironing board](https://images.trvl-media.com/lodging/4000000/3060000/3052600/3052573/d9a6f0f6.jpg?impolicy=fcrop&w=357&h=201&p=1&q=medium) ![Individually decorated, individually furnished, desk, iron/ironing board](https://images.trvl-media.com/lodging/4000000/3060000/3052600/3052573/5d13cb6a.jpg?impolicy=fcrop&w=357&h=201&p=1&q=medium) ![Individually decorated, individually furnished, desk, iron/ironing board](https://images.trvl-media.com/lodging/4000000/3060000/3052600/3052573/f8f95857.jpg?impolicy=fcrop&w=357&h=201&p=1&q=medium) ### Rodeway Inn & Suites Austin 6.6/10 (425) "Yes on pet friendly, didnt use laundry facilities " ![United States](https://a.travel-assets.com/egds/marks/flags/us.svg) Drew CA $73 CA $81 total includes taxes & fees Jan 8 - Jan 9, 2026 [](https://www.expedia.ca/Rochester-Hotels-Rodeway-Inn-Suites.h3052573.Hotel-Information) ![Desk, blackout drapes, free cribs/infant beds, free WiFi](https://images.trvl-media.com/lodging/1000000/30000/24600/24556/35bf11b4.jpg?impolicy=fcrop&w=357&h=201&p=1&q=medium) ![Suite, 1 King Bed, Refrigerator & Microwave | Living area](https://images.trvl-media.com/lodging/1000000/30000/24600/24556/e46b3aff.jpg?impolicy=fcrop&w=357&h=201&p=1&q=medium) ![Reception](https://images.trvl-media.com/lodging/1000000/30000/24600/24556/faaf4a01.jpg?impolicy=fcrop&w=357&h=201&p=1&q=medium) ![Front of property - evening/night](https://images.trvl-media.com/lodging/1000000/30000/24600/24556/c1e3f26e.jpg?impolicy=fcrop&w=357&h=201&p=1&q=medium) ### Days Inn by Wyndham Mason City Mason City 7.0/10 Good (810) "Very nice and understanding staff, good atmosphere " ![United States](https://a.travel-assets.com/egds/marks/flags/us.svg) Daeja CA $82 CA $92 total includes taxes & fees Dec 14 - Dec 15 [](https://www.expedia.ca/Mason-City-Hotels-Days-Inn-By-Wyndham-Mason-City.h24556.Hotel-Information) Lowest nightly price found within the past 24 hours based on a 1 night stay for 2 adults. Prices and availability subject to change. Additional terms may apply. [View all properties](https://expedia.ca/Hotel-Search?startDate=2025-12-23&endDate=2025-12-24®ionId=6024275&adults=2&travelerType=business_friendly&sort=RECOMMENDED&openPlayBack=true) ## Top Osage Hotel Reviews ![Rodeway Inn & Suites](https://images.trvl-media.com/lodging/4000000/3060000/3052600/3052573/4e051bf1_y.jpg) ### Rodeway Inn & Suites 10/10 Excellent "Yes on pet friendly, didnt use laundry facilities " [](https://expedia.ca/Rochester-Hotels-Rodeway-Inn-Suites.h3052573.Hotel-Information) ![Diamond Jo Worth Casino Hotel](https://images.trvl-media.com/lodging/2000000/1590000/1580600/1580597/f073330b_y.jpg) ### Diamond Jo Worth Casino Hotel 10/10 Excellent "Yes" [](https://expedia.ca/Northwood-Hotels-Country-Inn-Suites-By-Radisson.h1580597.Hotel-Information) ![Hampton Inn & Suites Mason City](https://images.trvl-media.com/lodging/16000000/15040000/15038000/15037932/2e8671ce_y.jpg) ### Hampton Inn & Suites Mason City 10/10 Excellent "Staff was great. Very clean." [](https://expedia.ca/Mason-City-Hotels-Hampton-Inn-Suites-Mason-City.h15037932.Hotel-Information) ![Days Inn by Wyndham Mason City](https://images.trvl-media.com/lodging/1000000/30000/24600/24556/35bf11b4_y.jpg) ### Days Inn by Wyndham Mason City 10/10 Excellent "Affordable , clean and helpful crew" [](https://expedia.ca/Mason-City-Hotels-Days-Inn-By-Wyndham-Mason-City.h24556.Hotel-Information) ![Holiday Inn Express and Suites Mason City by IHG](https://images.trvl-media.com/lodging/5000000/4160000/4156200/4156181/a8f9fb27_y.jpg) ### Holiday Inn Express and Suites Mason City by IHG 10/10 Excellent "👍" [](https://expedia.ca/Mason-City-Hotels-Holiday-Inn-Express-And-Suites-Mason-City.h4156181.Hotel-Information) ![Microtel Inn & Suites By Wyndham Clear Lake](https://images.trvl-media.com/lodging/1000000/530000/523200/523133/9e1ed185_y.jpg) ### Microtel Inn & Suites By Wyndham Clear Lake 10/10 Excellent "Room was clean and staff was friendly." [](https://expedia.ca/Mason-City-Hotels-Microtel-Inn-Suites-By-Wyndham-Clear-Lake.h523133.Hotel-Information) ![AmericInn by Wyndham Clear Lake](https://images.trvl-media.com/lodging/1000000/660000/658100/658042/4b3ca419_y.jpg) ### AmericInn by Wyndham Clear Lake 10/10 Excellent "Guy at front desk was super helpful and nice. Room was clean. The night shift lady was also super nice. And the breakfast was awesome. So many things to choose from. Best place to stay in the area" [](https://expedia.ca/Mason-City-Hotels-AmericInn-By-Wyndham-Clear-Lake.h658042.Hotel-Information) ![Best Western Holiday Lodge](https://images.trvl-media.com/lodging/1000000/10000/8200/8162/6f2156e8_y.jpg) ### Best Western Holiday Lodge 10/10 Excellent "Yes" [](https://expedia.ca/Mason-City-Hotels-Best-Western-Holiday-Lodge.h8162.Hotel-Information) ![Holiday Inn Express Hotel & Suites Northwood by IHG](https://images.trvl-media.com/lodging/5000000/4150000/4141200/4141196/b9ec7d0e_y.jpg) ### Holiday Inn Express Hotel & Suites Northwood by IHG 10/10 Excellent "The hotel was spotless in all areas. Staff was very friendly and check-in was quick and easy." [](https://expedia.ca/Mason-City-Hotels-Holiday-Inn-Express-Hotel-Suites-Northwood.h4141196.Hotel-Information) ## Frequently asked questions ### How much do business-friendly hotels in Osage cost? ### What are the top business-friendly motels in Osage? ### Why book your business-friendly hotel in Osage with Expedia? ### How can I find cheap business-friendly hotels in Osage? ### What is there to do in Osage near my business-friendly hotel? ## Explore a world of travel with Expedia - Lodging - Flights - Packages - Cars - Vacation Rental - More ways to book - [Hostels in Alta Vista ](https://www.expedia.ca/Alta-Vista-Hostels.d553248634983494311-aaHostels.Travel-Guide-Accommodation) - [Cheap Hotels in Alta Vista ](https://www.expedia.ca/Alta-Vista-Hotels-Cheap-Hotels.0-0-d553248634983494311-tCheapHotels.Travel-Guide-Filter-Hotels) - [Alta Vista Hotels ](https://www.expedia.ca/Alta-Vista-Hotels.d553248634983494311.Travel-Guide-Hotels) - [Apartments in Bassett ](https://www.expedia.ca/Bassett-Apartments.d553248634983084993-aaApartments.Travel-Guide-Accommodation) - 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