Title: Book the Best Ortygia Adults Only Resorts & Hotels in 2025 | Expedia.ca [Ortygia Travel Guide](https://expedia.ca/Ortygia.dx6182482)[Hotels in Ortygia](https://expedia.ca/Ortygia-Hotels.d6182482.Travel-Guide-Hotels)[Vacation Rentals in Ortygia](https://expedia.ca/Ortygia-Vacation-Rentals.d6182482.Travel-Guide-VacationRentals)[Flights to Ortygia](https://expedia.ca/Cheap-Flights-To-Ortygia.d6182482.Travel-Guide-Flights)[Things to do in Ortygia](https://expedia.ca/Things-To-Do-In-Ortygia.d6182482.Travel-Guide-Activities)[Ortygia Car Rentals](https://expedia.ca/Car-Rentals-In-Ortygia.d6182482.Car-Rental-Guide)[Ortygia Vacation Packages](https://expedia.ca/Ortygia.d6182482.Destination-Travel-Guides) ![Ortygia which includes street scenes and markets as well as a small group of people](https://a.travel-assets.com/findyours-php/viewfinder/images/res70/87000/87652-Ortygia.jpg?impolicy=fcrop&w=1200&h=500&q=medium) # Find Adults Only Resorts & Hotels in Ortygia ![calendar shield illustration](https://a.travel-assets.com/travel-assets-manager/pictogram-bex/light__calendar_shield.svg) ### Change your mind Book hotels with free cancellation ![deals illustration](https://a.travel-assets.com/travel-assets-manager/pictogram-bex/light__deals.svg) ### Treat yourself Sign in to save 10% or more on thousands of hotels [Sign in](https://www.expedia.ca/login) ![bed illustration](https://a.travel-assets.com/travel-assets-manager/pictogram-bex/light__bed.svg) ### Be picky Search almost a million properties worldwide ## Check availability on Ortygia Adults Only Resorts & Hotels Tonight [Sep 27 - 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