Title: Book the Best Orangeburg Hotels with smoking rooms in 2026 from CA $84 | Expedia.ca [Orangeburg Travel Guide](https://expedia.ca/Orangeburg.dx6058108)[Hotels in Orangeburg](https://expedia.ca/Orangeburg-Hotels.d6058108.Travel-Guide-Hotels)[Vacation Rentals in Orangeburg](https://expedia.ca/Orangeburg-Vacation-Rentals.d6058108.Travel-Guide-VacationRentals)[Flights to Orangeburg](https://expedia.ca/Cheap-Flights-To-Orangeburg.d6058108.Travel-Guide-Flights)[Orangeburg Car Rentals](https://expedia.ca/Car-Rentals-In-Orangeburg.d6058108.Car-Rental-Guide)[Orangeburg Vacation Packages](https://expedia.ca/Orangeburg.d6058108.Destination-Travel-Guides) ![Cypress Trees with Spanish Moss growing on them. In Lake Marion at Santee State Park, Santee, Orangeburg County, South Carolina](https://images.trvl-media.com/place/6058108/7d590932-d0d2-48e4-90bf-23f9acc0734e.jpg?impolicy=fcrop&w=1200&h=500&q=medium) ![](https://images.trvl-media.com/place/6058108/7d590932-d0d2-48e4-90bf-23f9acc0734e.jpg?impolicy=fcrop&w=1200&h=500&q=medium) - ![](https://a.travel-assets.com/travel-assets-manager/pictogram-bex/light__calendar_shield.svg) ### Change your mind Book hotels with free cancellation - ![](https://a.travel-assets.com/travel-assets-manager/pictogram-bex/light__deals.svg) ### Treat yourself Sign in to save 10% or more on thousands of hotels [Sign in](https://www.expedia.ca/login) - ![](https://a.travel-assets.com/travel-assets-manager/pictogram-bex/light__bed.svg) ### Be picky Search almost a million properties worldwide ## Check availability on Orangeburg Hotels with smoking rooms Tonight [Feb 5 - Feb 6](https://www.expedia.ca/Hotel-Search?regionId=6058108&startDate=2026-02-05&endDate=2026-02-06&adults=2&rfrr=TG.LP.CheckPrices.Hotel&openPlayBack=true) Tomorrow [Feb 6 - Feb 7](https://www.expedia.ca/Hotel-Search?regionId=6058108&startDate=2026-02-06&endDate=2026-02-07&adults=2&rfrr=TG.LP.CheckPrices.Hotel&openPlayBack=true) This weekend [Feb 6 - Feb 8](https://www.expedia.ca/Hotel-Search?regionId=6058108&startDate=2026-02-06&endDate=2026-02-08&adults=2&rfrr=TG.LP.CheckPrices.Hotel&openPlayBack=true) Next weekend [Feb 13 - Feb 15](https://www.expedia.ca/Hotel-Search?regionId=6058108&startDate=2026-02-13&endDate=2026-02-15&adults=2&rfrr=TG.LP.CheckPrices.Hotel&openPlayBack=true) ## Our top choices for Orangeburg hotels with designated smoking areas ![Property amenity](https://images.trvl-media.com/lodging/55000000/54940000/54931500/54931475/27e78d69.jpg?impolicy=fcrop&w=357&h=201&p=1&q=medium) ![Free WiFi, bed sheets](https://images.trvl-media.com/lodging/55000000/54940000/54931500/54931475/e5b64ae6.jpg?impolicy=fcrop&w=357&h=201&p=1&q=medium) ![Property amenity](https://images.trvl-media.com/lodging/55000000/54940000/54931500/54931475/8229e487.jpg?impolicy=fcrop&w=357&h=201&p=1&q=medium) ![Lobby lounge](https://images.trvl-media.com/lodging/55000000/54940000/54931500/54931475/e0b4742d.jpg?impolicy=fcrop&w=357&h=201&p=1&q=medium) ### SpringHill Suites by Marriott Orangeburg [](https://www.expedia.ca/Orangeburg-Hotels-SpringHill-Suites-Orangeburg.h54931475.Hotel-Information) Orangeburg 8.8/10 Excellent (696 reviews) "Nice roomy clean rooms, staff were great, indoor heated pool was nice accomadation for this time of year for the kids. " ![United States](https://a.travel-assets.com/egds/marks/flags/us.svg) Lisa CA $143 CA $159 total includes taxes & fees Feb 26 - Feb 27 [](https://www.expedia.ca/Orangeburg-Hotels-SpringHill-Suites-Orangeburg.h54931475.Hotel-Information) ![Lobby](https://images.trvl-media.com/lodging/1000000/300000/297200/297104/97d6098f.jpg?impolicy=fcrop&w=357&h=201&p=1&q=medium) ![Standard Room, 1 King Bed, Non Smoking](https://images.trvl-media.com/lodging/1000000/300000/297200/297104/bc1bdbe2.jpg?impolicy=fcrop&w=357&h=201&p=1&q=medium) ![Seasonal outdoor pool](https://images.trvl-media.com/lodging/1000000/300000/297200/297104/2616bf68.jpg?impolicy=fcrop&w=357&h=201&p=1&q=medium) ![Lobby](https://images.trvl-media.com/lodging/1000000/300000/297200/297104/5e401dfa.jpg?impolicy=fcrop&w=357&h=201&p=1&q=medium) ### Sleep Inn Orangeburg [](https://www.expedia.ca/Orangeburg-Hotels-Sleep-Inn-Orangeburg.h297104.Hotel-Information) Orangeburg 7.8/10 Good (397 reviews) "Very clean, comfortable beds, friendly staff. would stay here again." ![United States](https://a.travel-assets.com/egds/marks/flags/us.svg) Michele CA $98 CA $109 total includes taxes & fees Mar 8 - Mar 9 [](https://www.expedia.ca/Orangeburg-Hotels-Sleep-Inn-Orangeburg.h297104.Hotel-Information) ![Desk, laptop workspace, free WiFi, bed sheets](https://images.trvl-media.com/lodging/126000000/125190000/125185400/125185326/47b4af62.jpg?impolicy=fcrop&w=357&h=201&p=1&q=medium) ![Room, 2 Queen Beds | Private kitchenette](https://images.trvl-media.com/lodging/126000000/125190000/125185400/125185326/60d574cc.jpg?impolicy=fcrop&w=357&h=201&p=1&q=medium) ![Front of property](https://images.trvl-media.com/lodging/126000000/125190000/125185400/125185326/5bdd7f41.jpg?impolicy=fcrop&w=357&h=201&p=1&q=medium) ![Free daily continental breakfast](https://images.trvl-media.com/lodging/126000000/125190000/125185400/125185326/b1c852d6.jpg?impolicy=fcrop&w=357&h=201&p=1&q=medium) ### Southern Lodge 601 [](https://www.expedia.ca/Orangeburg-Hotels-Southern-Lodge-601.h125185326.Hotel-Information) Orangeburg CA $79 CA $88 total includes taxes & fees Feb 27 - Feb 28 [](https://www.expedia.ca/Orangeburg-Hotels-Southern-Lodge-601.h125185326.Hotel-Information) ![Suite, 1 King Bed, Accessible, Smoking](https://images.trvl-media.com/lodging/1000000/20000/15200/15145/81259c64.jpg?impolicy=fcrop&w=357&h=201&p=1&q=medium) ![Lobby](https://images.trvl-media.com/lodging/1000000/20000/15200/15145/706081d4.jpg?impolicy=fcrop&w=357&h=201&p=1&q=medium) ![Outdoor pool](https://images.trvl-media.com/lodging/1000000/20000/15200/15145/d44bb419.jpg?impolicy=fcrop&w=357&h=201&p=1&q=medium) ![Free daily continental breakfast](https://images.trvl-media.com/lodging/1000000/20000/15200/15145/3f3e2740.jpg?impolicy=fcrop&w=357&h=201&p=1&q=medium) ### Quality Inn & Suites Orangeburg [](https://www.expedia.ca/Orangeburg-Hotels-Quality-Inn-Suites.h15145.Hotel-Information) Orangeburg 6.2/10 (636 reviews) "The room was very clean" ![United States](https://a.travel-assets.com/egds/marks/flags/us.svg) Judith CA $80 CA $89 total includes taxes & fees Feb 12 - Feb 13 [](https://www.expedia.ca/Orangeburg-Hotels-Quality-Inn-Suites.h15145.Hotel-Information) ![Front of property - evening/night](https://images.trvl-media.com/lodging/17000000/16010000/16006800/16006797/bba9f28a.jpg?impolicy=fcrop&w=357&h=201&p=1&q=medium) ![Standard Room, 1 King Bed, Jetted Tub | Jetted tub](https://images.trvl-media.com/lodging/17000000/16010000/16006800/16006797/d82c7e6a.jpg?impolicy=fcrop&w=357&h=201&p=1&q=medium) ![Standard Room, 1 King Bed, Jetted Tub](https://images.trvl-media.com/lodging/17000000/16010000/16006800/16006797/3e6ea1ed.jpg?impolicy=fcrop&w=357&h=201&p=1&q=medium) ![Standard Room, 1 King Bed, Jetted Tub](https://images.trvl-media.com/lodging/17000000/16010000/16006800/16006797/60427df0.jpg?impolicy=fcrop&w=357&h=201&p=1&q=medium) ### Southern Lodge & Suites [](https://www.expedia.ca/Orangeburg-Hotels-Southern-Lodge-Suites.h16006797.Hotel-Information) Orangeburg 5.6/10 (77 reviews) "This was a great safe place to stay food options and store in walking distance staff was friendly " ![United States](https://a.travel-assets.com/egds/marks/flags/us.svg) Gloria CA $68 CA $84 total includes taxes & fees Feb 21 - Feb 22 [](https://www.expedia.ca/Orangeburg-Hotels-Southern-Lodge-Suites.h16006797.Hotel-Information) ![Room, 2 Queen Beds, Kitchenette](https://images.trvl-media.com/lodging/113000000/112650000/112646100/112646069/a6f22b80.jpg?impolicy=fcrop&w=357&h=201&p=1&q=medium) ![Exterior](https://images.trvl-media.com/lodging/113000000/112650000/112646100/112646069/bde7bffe.jpg?impolicy=fcrop&w=357&h=201&p=1&q=medium) ![Room, 2 Queen Beds, Kitchenette | Private kitchenette](https://images.trvl-media.com/lodging/113000000/112650000/112646100/112646069/032950d3.jpg?impolicy=fcrop&w=357&h=201&p=1&q=medium) ![Reception](https://images.trvl-media.com/lodging/113000000/112650000/112646100/112646069/bf833d46.jpg?impolicy=fcrop&w=357&h=201&p=1&q=medium) ### Crown Inn By Oyo Orangeburg Hwy 301 [](https://www.expedia.ca/Orangeburg-Hotels-Crown-Inn-By-Oyo-Orangeburg-Hwy-301.h112646069.Hotel-Information) Orangeburg 3.0/10 (6 reviews) "Nothing was placed i ever stayed " ![United States](https://a.travel-assets.com/egds/marks/flags/us.svg) Bruce [](https://www.expedia.ca/Orangeburg-Hotels-Crown-Inn-By-Oyo-Orangeburg-Hwy-301.h112646069.Hotel-Information) ![Frette Italian sheets, premium bedding, pillowtop beds, blackout drapes](https://images.trvl-media.com/lodging/1000000/520000/518500/518401/fc94b516.jpg?impolicy=fcrop&w=357&h=201&p=1&q=medium) ![Lobby](https://images.trvl-media.com/lodging/1000000/520000/518500/518401/8e89959e.jpg?impolicy=fcrop&w=357&h=201&p=1&q=medium) ![Frette Italian sheets, premium bedding, pillowtop beds, blackout drapes](https://images.trvl-media.com/lodging/1000000/520000/518500/518401/91286f8a.jpg?impolicy=fcrop&w=357&h=201&p=1&q=medium) ![Lobby](https://images.trvl-media.com/lodging/1000000/520000/518500/518401/2824d996.jpg?impolicy=fcrop&w=357&h=201&p=1&q=medium) ### Comfort Inn & Suites Santee [](https://www.expedia.ca/Orangeburg-Hotels-Comfort-Inn-Suites-Santee.h518401.Hotel-Information) Santee 8.0/10 Very good (1,003 reviews) "Clean rooms, nice staff, decent breakfast " ![United States](https://a.travel-assets.com/egds/marks/flags/us.svg) Dale CA $137 CA $152 total includes taxes & fees Feb 15 - Feb 16 [](https://www.expedia.ca/Orangeburg-Hotels-Comfort-Inn-Suites-Santee.h518401.Hotel-Information) ![Lobby](https://images.trvl-media.com/lodging/57000000/56230000/56228900/56228813/962a9377.jpg?impolicy=fcrop&w=357&h=201&p=1&q=medium) ![Exterior](https://images.trvl-media.com/lodging/57000000/56230000/56228900/56228813/27b2c420.jpg?impolicy=fcrop&w=357&h=201&p=1&q=medium) ![Lobby](https://images.trvl-media.com/lodging/57000000/56230000/56228900/56228813/d3f2bbda.jpg?impolicy=fcrop&w=357&h=201&p=1&q=medium) ![Superior Room, 1 King Bed, Non Smoking](https://images.trvl-media.com/lodging/57000000/56230000/56228900/56228813/11ccce69.jpg?impolicy=fcrop&w=357&h=201&p=1&q=medium) ### Red Roof Inn St George, SC [](https://www.expedia.ca/Walterboro-St-George-Hotels-Red-Roof-Inn-St-George.h56228813.Hotel-Information) St. George 7.4/10 Good (653 reviews) "Breakfast was an overstatement!!" ![United States](https://a.travel-assets.com/egds/marks/flags/us.svg) Nicki CA $103 CA $114 total includes taxes & fees Feb 27 - Feb 28 [](https://www.expedia.ca/Walterboro-St-George-Hotels-Red-Roof-Inn-St-George.h56228813.Hotel-Information) ![Desk, blackout drapes, iron/ironing board, free WiFi](https://images.trvl-media.com/lodging/3000000/2920000/2911400/2911319/c1880a3d.jpg?impolicy=fcrop&w=357&h=201&p=1&q=medium) ![Combined shower/tub, hair dryer, towels](https://images.trvl-media.com/lodging/3000000/2920000/2911400/2911319/bc8b5a93.jpg?impolicy=fcrop&w=357&h=201&p=1&q=medium) ![Front of property](https://images.trvl-media.com/lodging/3000000/2920000/2911400/2911319/3a41c72c.jpg?impolicy=fcrop&w=357&h=201&p=1&q=medium) ![Free daily continental breakfast](https://images.trvl-media.com/lodging/3000000/2920000/2911400/2911319/efa2345e.jpg?impolicy=fcrop&w=357&h=201&p=1&q=medium) ### Peach Tree Inn [](https://www.expedia.ca/St-George-Hotels-Peach-Tree-Inn.h2911319.Hotel-Information) St. George 7.4/10 Good (161 reviews) "Clean rooms and pleasant staff. Could use newer towels. " ![United States](https://a.travel-assets.com/egds/marks/flags/us.svg) Patricia CA $83 CA $90 total includes taxes & fees Feb 10 - Feb 11 [](https://www.expedia.ca/St-George-Hotels-Peach-Tree-Inn.h2911319.Hotel-Information) ![In-room safe, iron/ironing board, free WiFi, bed sheets](https://images.trvl-media.com/lodging/6000000/5640000/5630800/5630775/28717b40.jpg?impolicy=fcrop&w=357&h=201&p=1&q=medium) ![Exterior](https://images.trvl-media.com/lodging/6000000/5640000/5630800/5630775/4ab49efd.jpg?impolicy=fcrop&w=357&h=201&p=1&q=medium) ![Business centre](https://images.trvl-media.com/lodging/6000000/5640000/5630800/5630775/eeb5fa18.jpg?impolicy=fcrop&w=357&h=201&p=1&q=medium) ![Bathtub, free toiletries, hair dryer, towels](https://images.trvl-media.com/lodging/6000000/5640000/5630800/5630775/ebe97e99.jpg?impolicy=fcrop&w=357&h=201&p=1&q=medium) ### Travelodge by Wyndham Santee [](https://www.expedia.ca/Orangeburg-Hotels-Travelodge-By-Wyndham-Santee.h5630775.Hotel-Information) Santee 7.0/10 Good (695 reviews) "Nice quiet room and a delicious breakfast at a reasonable rate." ![United States](https://a.travel-assets.com/egds/marks/flags/us.svg) Joseph B CA $85 CA $94 total includes taxes & fees Feb 23 - Feb 24 [](https://www.expedia.ca/Orangeburg-Hotels-Travelodge-By-Wyndham-Santee.h5630775.Hotel-Information) Lowest nightly price found within the past 24 hours based on a 1 night stay for 2 adults. Prices and availability subject to change. Additional terms may apply. [View all properties](https://expedia.ca/Hotel-Search?startDate=2026-02-19&endDate=2026-02-20®ionId=6058108&adults=2&property_amenities_group_explore=designated_smoking_areas&sort=RECOMMENDED&openPlayBack=true) ## Top Orangeburg Hotel Reviews ![Spark by Hilton Orangeburg](https://images.trvl-media.com/lodging/2000000/1880000/1878000/1877930/8acfa265_y.jpg) ### Spark by Hilton Orangeburg 10/10 Excellent "Room was very clean. Front desk was helpful and courteous with quick check-in. Good breakfast" [](https://expedia.ca/Orangeburg-Hotels-Spark-By-Hilton-Orangeburg.h1877930.Hotel-Information) ![Travelodge by Wyndham Orangeburg](https://images.trvl-media.com/lodging/18000000/17390000/17380300/17380261/bfdc100f_y.jpg) ### Travelodge by Wyndham Orangeburg 10/10 Excellent "Property and rooms, super clean, staff is always up to top level, helpful and efficient. An older property but splendidly maintained. The best value for money in the whole cluster of hotels and exit 145 of 26.. 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