Title: Book the Best BUSINESS Hotels in Orangeburg in 2026 | Expedia.ca [Orangeburg Travel Guide](https://expedia.ca/Orangeburg.dx6058108)[Hotels in Orangeburg](https://expedia.ca/Orangeburg-Hotels.d6058108.Travel-Guide-Hotels)[Vacation Rentals in Orangeburg](https://expedia.ca/Orangeburg-Vacation-Rentals.d6058108.Travel-Guide-VacationRentals)[Flights to Orangeburg](https://expedia.ca/Cheap-Flights-To-Orangeburg.d6058108.Travel-Guide-Flights)[Orangeburg Car Rentals](https://expedia.ca/Car-Rentals-In-Orangeburg.d6058108.Car-Rental-Guide)[Orangeburg Vacation Packages](https://expedia.ca/Orangeburg.d6058108.Destination-Travel-Guides) ![Cypress Trees with Spanish Moss growing on them. In Lake Marion at Santee State Park, Santee, Orangeburg County, South Carolina](https://images.trvl-media.com/place/6058108/7d590932-d0d2-48e4-90bf-23f9acc0734e.jpg?impolicy=fcrop&w=1200&h=500&q=medium) # Find Business Hotels in Orangeburg, SC from CA $84 - ![](https://a.travel-assets.com/travel-assets-manager/pictogram-bex/light__calendar_shield.svg) ### Change your mind Book hotels with free cancellation - ![](https://a.travel-assets.com/travel-assets-manager/pictogram-bex/light__deals.svg) ### Treat yourself Sign in to save 10% or more on thousands of hotels [Sign in](https://www.expedia.ca/login) - ![](https://a.travel-assets.com/travel-assets-manager/pictogram-bex/light__bed.svg) ### Be picky Search almost a million properties worldwide ## Check availability on Orangeburg Business Hotels Tonight [Dec 29 - Dec 30](https://www.expedia.ca/Hotel-Search?regionId=6058108&startDate=2025-12-29&endDate=2025-12-30&adults=2&rfrr=TG.LP.CheckPrices.Hotel&openPlayBack=true&travelerType=business_friendly) Tomorrow [Dec 30 - Dec 31](https://www.expedia.ca/Hotel-Search?regionId=6058108&startDate=2025-12-30&endDate=2025-12-31&adults=2&rfrr=TG.LP.CheckPrices.Hotel&openPlayBack=true&travelerType=business_friendly) This weekend [Jan 2 - Jan 4](https://www.expedia.ca/Hotel-Search?regionId=6058108&startDate=2026-01-02&endDate=2026-01-04&adults=2&rfrr=TG.LP.CheckPrices.Hotel&openPlayBack=true&travelerType=business_friendly) Next weekend [Jan 9 - Jan 11](https://www.expedia.ca/Hotel-Search?regionId=6058108&startDate=2026-01-09&endDate=2026-01-11&adults=2&rfrr=TG.LP.CheckPrices.Hotel&openPlayBack=true&travelerType=business_friendly) ## Our top choices for Orangeburg business-friendly hotels ![Reception](https://images.trvl-media.com/lodging/1000000/570000/564000/563976/aa173c27.jpg?impolicy=fcrop&w=357&h=201&p=1&q=medium) ![Premium bedding, pillowtop beds, in-room safe, desk](https://images.trvl-media.com/lodging/1000000/570000/564000/563976/c7fdb599.jpg?impolicy=fcrop&w=357&h=201&p=1&q=medium) ![Seasonal outdoor pool](https://images.trvl-media.com/lodging/1000000/570000/564000/563976/6dc9f9a9.jpg?impolicy=fcrop&w=357&h=201&p=1&q=medium) ![Front of property](https://images.trvl-media.com/lodging/1000000/570000/564000/563976/f8fbcf77.jpg?impolicy=fcrop&w=357&h=201&p=1&q=medium) ### Fairfield Inn by Marriott Orangeburg [](https://www.expedia.ca/Orangeburg-Hotels-Fairfield-Inn-By-Marriott-Orangeburg.h563976.Hotel-Information) Orangeburg 8.4/10 Very good (704) "Overall a great place to stay!" ![United States](https://a.travel-assets.com/egds/marks/flags/us.svg) Troy CA $115 CA $127 total includes taxes & fees Jan 4 - Jan 5, 2026 [](https://www.expedia.ca/Orangeburg-Hotels-Fairfield-Inn-By-Marriott-Orangeburg.h563976.Hotel-Information) ![Free daily continental breakfast](https://images.trvl-media.com/lodging/2000000/1880000/1878000/1877930/8acfa265.jpg?impolicy=fcrop&w=357&h=201&p=1&q=medium) ![Reception](https://images.trvl-media.com/lodging/2000000/1880000/1878000/1877930/w3837h2557x3y3-7acc8337.jpg?impolicy=fcrop&w=357&h=201&p=1&q=medium) ![Terrace/patio](https://images.trvl-media.com/lodging/2000000/1880000/1878000/1877930/w3840h2557x0y3-a96a0495.jpg?impolicy=fcrop&w=357&h=201&p=1&q=medium) ![Seasonal outdoor pool](https://images.trvl-media.com/lodging/2000000/1880000/1878000/1877930/w3840h2556x0y4-5cb4ef80.jpg?impolicy=fcrop&w=357&h=201&p=1&q=medium) ### Spark by Hilton Orangeburg [](https://www.expedia.ca/Orangeburg-Hotels-Spark-By-Hilton-Orangeburg.h1877930.Hotel-Information) Orangeburg 7.8/10 Good (1004) "Great place and pet friendly. Rooms are clean and comfortable." ![United States](https://a.travel-assets.com/egds/marks/flags/us.svg) Penny CA $119 CA $132 total includes taxes & fees Dec 31 - Jan 1, 2026 [](https://www.expedia.ca/Orangeburg-Hotels-Spark-By-Hilton-Orangeburg.h1877930.Hotel-Information) ![Lobby](https://images.trvl-media.com/lodging/35000000/34330000/34323400/34323336/1bbd70f5.jpg?impolicy=fcrop&w=357&h=201&p=1&q=medium) ![Fitness studio](https://images.trvl-media.com/lodging/35000000/34330000/34323400/34323336/7b01c436.jpg?impolicy=fcrop&w=357&h=201&p=1&q=medium) ![Reception](https://images.trvl-media.com/lodging/35000000/34330000/34323400/34323336/a4197341.jpg?impolicy=fcrop&w=357&h=201&p=1&q=medium) ![Room, 2 Queen Beds, Accessible, Bathtub](https://images.trvl-media.com/lodging/35000000/34330000/34323400/34323336/57735ca3.jpg?impolicy=fcrop&w=357&h=201&p=1&q=medium) ### Tru by Hilton Orangeburg [](https://www.expedia.ca/Orangeburg-Hotels-Tru-By-Hilton-Orangeburg.h34323336.Hotel-Information) Orangeburg 9.2/10 Wonderful (1012) "Great stay" ![United States](https://a.travel-assets.com/egds/marks/flags/us.svg) Thomas CA $145 CA $161 total includes taxes & fees Jan 11 - Jan 12, 2026 [](https://www.expedia.ca/Orangeburg-Hotels-Tru-By-Hilton-Orangeburg.h34323336.Hotel-Information) ![Desk, iron/ironing board, free cribs/infant beds, free WiFi](https://images.trvl-media.com/lodging/2000000/2000000/1990300/1990272/377ba79f.jpg?impolicy=fcrop&w=357&h=201&p=1&q=medium) ![Room, 2 Queen Beds, Accessible, Non Smoking (Efficiency)](https://images.trvl-media.com/lodging/2000000/2000000/1990300/1990272/1c1fc707.jpg?impolicy=fcrop&w=357&h=201&p=1&q=medium) ![Desk, iron/ironing board, free cribs/infant beds, free WiFi](https://images.trvl-media.com/lodging/2000000/2000000/1990300/1990272/208c4454.jpg?impolicy=fcrop&w=357&h=201&p=1&q=medium) ![Exterior](https://images.trvl-media.com/lodging/2000000/2000000/1990300/1990272/5fe5c871.jpg?impolicy=fcrop&w=357&h=201&p=1&q=medium) ### Comfort Inn & Suites Orangeburg [](https://www.expedia.ca/Orangeburg-Hotels-Comfort-Inn-Suites.h1990272.Hotel-Information) Orangeburg 8.0/10 Very good (558) "Would recommend this hotel for out of town guest with no hesitation. " ![United States](https://a.travel-assets.com/egds/marks/flags/us.svg) Yvette CA $130 CA $144 total includes taxes & fees Jan 4 - Jan 5, 2026 [](https://www.expedia.ca/Orangeburg-Hotels-Comfort-Inn-Suites.h1990272.Hotel-Information) ![Exterior](https://images.trvl-media.com/lodging/10000000/9860000/9854700/9854604/637dd914.jpg?impolicy=fcrop&w=357&h=201&p=1&q=medium) ![Outdoor pool, sun loungers](https://images.trvl-media.com/lodging/10000000/9860000/9854700/9854604/ca4d16db.jpg?impolicy=fcrop&w=357&h=201&p=1&q=medium) ![In-room safe, desk, blackout drapes, iron/ironing board](https://images.trvl-media.com/lodging/10000000/9860000/9854700/9854604/f8dc077a.jpg?impolicy=fcrop&w=357&h=201&p=1&q=medium) ![In-room safe, desk, blackout drapes, iron/ironing board](https://images.trvl-media.com/lodging/10000000/9860000/9854700/9854604/133748ec.jpg?impolicy=fcrop&w=357&h=201&p=1&q=medium) ### Hampton Inn & Suites Orangeburg [](https://www.expedia.ca/Orangeburg-Hotels-Hampton-Inn-Suites-Orangeburg.h9854604.Hotel-Information) Orangeburg 9.4/10 Exceptional (763) "Great stay!" ![United States](https://a.travel-assets.com/egds/marks/flags/us.svg) Sonovia CA $178 CA $198 total includes taxes & fees Jan 18 - Jan 19, 2026 [](https://www.expedia.ca/Orangeburg-Hotels-Hampton-Inn-Suites-Orangeburg.h9854604.Hotel-Information) ![Exterior](https://images.trvl-media.com/lodging/1000000/600000/597800/597750/2e89db8e.jpg?impolicy=fcrop&w=357&h=201&p=1&q=medium) ![In-room safe, desk, iron/ironing board, free cribs/infant beds](https://images.trvl-media.com/lodging/1000000/600000/597800/597750/a07c5e78.jpg?impolicy=fcrop&w=357&h=201&p=1&q=medium) ![Free buffet breakfast](https://images.trvl-media.com/lodging/1000000/600000/597800/597750/acfce64d.jpg?impolicy=fcrop&w=357&h=201&p=1&q=medium) ![Exterior](https://images.trvl-media.com/lodging/1000000/600000/597800/597750/c4341f52.jpg?impolicy=fcrop&w=357&h=201&p=1&q=medium) ### Holiday Inn Express & Suites Orangeburg by IHG [](https://www.expedia.ca/Orangeburg-Hotels-Holiday-Inn-Express-Hotel-Suites-Orangeburg.h597750.Hotel-Information) Orangeburg 8.6/10 Excellent (795) "The room was spotless and the staff was courteous. " ![United States](https://a.travel-assets.com/egds/marks/flags/us.svg) Terrance CA $161 CA $179 total includes taxes & fees Jan 18 - Jan 19, 2026 [](https://www.expedia.ca/Orangeburg-Hotels-Holiday-Inn-Express-Hotel-Suites-Orangeburg.h597750.Hotel-Information) ![Lobby](https://images.trvl-media.com/lodging/1000000/300000/297200/297104/97d6098f.jpg?impolicy=fcrop&w=357&h=201&p=1&q=medium) ![Lobby](https://images.trvl-media.com/lodging/1000000/300000/297200/297104/5e401dfa.jpg?impolicy=fcrop&w=357&h=201&p=1&q=medium) ![Seasonal outdoor pool](https://images.trvl-media.com/lodging/1000000/300000/297200/297104/02857169.jpg?impolicy=fcrop&w=357&h=201&p=1&q=medium) ![Room, 2 Double Beds, Non Smoking](https://images.trvl-media.com/lodging/1000000/300000/297200/297104/a152b78a.jpg?impolicy=fcrop&w=357&h=201&p=1&q=medium) ### Sleep Inn Orangeburg [](https://www.expedia.ca/Orangeburg-Hotels-Sleep-Inn-Orangeburg.h297104.Hotel-Information) Orangeburg 7.8/10 Good (386) "We were only here for one night. The room was clean and the breakfast was good. The only bad thing is there are very few sit down restaurants. Went to Applebees and it was horrible! " ![United States](https://a.travel-assets.com/egds/marks/flags/us.svg) Judy CA $115 CA $128 total includes taxes & fees Jan 25 - Jan 26, 2026 [](https://www.expedia.ca/Orangeburg-Hotels-Sleep-Inn-Orangeburg.h297104.Hotel-Information) ![Lobby](https://images.trvl-media.com/lodging/1000000/20000/15200/15145/f9528bb1.jpg?impolicy=fcrop&w=357&h=201&p=1&q=medium) ![Suite, 1 King Bed, Accessible, Smoking](https://images.trvl-media.com/lodging/1000000/20000/15200/15145/81259c64.jpg?impolicy=fcrop&w=357&h=201&p=1&q=medium) ![Outdoor pool](https://images.trvl-media.com/lodging/1000000/20000/15200/15145/d44bb419.jpg?impolicy=fcrop&w=357&h=201&p=1&q=medium) ![Free daily continental breakfast](https://images.trvl-media.com/lodging/1000000/20000/15200/15145/0d1ec0e1.jpg?impolicy=fcrop&w=357&h=201&p=1&q=medium) ### Quality Inn & Suites Orangeburg [](https://www.expedia.ca/Orangeburg-Hotels-Quality-Inn-Suites.h15145.Hotel-Information) Orangeburg 6.2/10 (627) "Great motel, excellent staff, noisy neighborhood " ![United States](https://a.travel-assets.com/egds/marks/flags/us.svg) Maurie CA $80 CA $89 total includes taxes & fees Jan 5 - Jan 6, 2026 [](https://www.expedia.ca/Orangeburg-Hotels-Quality-Inn-Suites.h15145.Hotel-Information) ![Free daily on-the-go breakfast](https://images.trvl-media.com/lodging/1000000/40000/34400/34400/c9ac8d21.jpg?impolicy=fcrop&w=357&h=201&p=1&q=medium) ![Room, 1 King Bed, Non Smoking](https://images.trvl-media.com/lodging/1000000/40000/34400/34400/a8856fea.jpg?impolicy=fcrop&w=357&h=201&p=1&q=medium) ![Pool](https://images.trvl-media.com/lodging/1000000/40000/34400/34400/c87bee2f.jpg?impolicy=fcrop&w=357&h=201&p=1&q=medium) ![Room amenity](https://images.trvl-media.com/lodging/1000000/40000/34400/34400/acf6709b.jpg?impolicy=fcrop&w=357&h=201&p=1&q=medium) ### Super 8 by Wyndham, Orangeburg [](https://www.expedia.ca/Orangeburg-Hotels-Super-8-By-Wyndham.h34400.Hotel-Information) Orangeburg 6.8/10 (898) "Lovely front desk staff, very clean everywhere and nice breakfast. " ![Canada](https://a.travel-assets.com/egds/marks/flags/ca.svg) Danica CA $79 CA $87 total includes taxes & fees Dec 30 - Dec 31 [](https://www.expedia.ca/Orangeburg-Hotels-Super-8-By-Wyndham.h34400.Hotel-Information) ![Seasonal outdoor pool](https://images.trvl-media.com/lodging/1000000/30000/20500/20500/3438166f.jpg?impolicy=fcrop&w=357&h=201&p=1&q=medium) ![Check-in/check-out kiosk](https://images.trvl-media.com/lodging/1000000/30000/20500/20500/3e8501ca.jpg?impolicy=fcrop&w=357&h=201&p=1&q=medium) ![Free daily buffet breakfast](https://images.trvl-media.com/lodging/1000000/30000/20500/20500/581bc335.jpg?impolicy=fcrop&w=357&h=201&p=1&q=medium) ![Mini-refrigerator](https://images.trvl-media.com/lodging/1000000/30000/20500/20500/de5b8443.jpg?impolicy=fcrop&w=357&h=201&p=1&q=medium) ### Baymont by Wyndham Orangeburg North [](https://www.expedia.ca/Orangeburg-Hotels-Baymont-By-Wyndham-Orangeburg-North.h20500.Hotel-Information) Orangeburg 6.0/10 (1002) "The room was clean, it just need updating. The tv was small" ![United States](https://a.travel-assets.com/egds/marks/flags/us.svg) Lyquita CA $76 CA $84 total includes taxes & fees Jan 5 - Jan 6, 2026 [](https://www.expedia.ca/Orangeburg-Hotels-Baymont-By-Wyndham-Orangeburg-North.h20500.Hotel-Information) Lowest nightly price found within the past 24 hours based on a 1 night stay for 2 adults. Prices and availability subject to change. Additional terms may apply. [View all properties](https://expedia.ca/Hotel-Search?startDate=2026-01-12&endDate=2026-01-13®ionId=6058108&adults=2&travelerType=business_friendly&sort=RECOMMENDED&openPlayBack=true) ## Top Orangeburg Hotel Reviews ![Hampton Inn & Suites Orangeburg](https://images.trvl-media.com/lodging/10000000/9860000/9854700/9854604/637dd914_y.jpg) ### Hampton Inn & Suites Orangeburg 10/10 Excellent "The staff was exceptional and willing to take care of extra needs that went above and beyond their normal scope of duty. Amazing breakfast! FIVE STARS ALL THE WAY! " [](https://expedia.ca/Orangeburg-Hotels-Hampton-Inn-Suites-Orangeburg.h9854604.Hotel-Information) ![Fairfield Inn by Marriott Orangeburg](https://images.trvl-media.com/lodging/1000000/570000/564000/563976/aa173c27_y.jpg) ### Fairfield Inn by Marriott Orangeburg 10/10 Excellent "Overall a great place to stay!" [](https://expedia.ca/Orangeburg-Hotels-Fairfield-Inn-By-Marriott-Orangeburg.h563976.Hotel-Information) ![Spark by Hilton Orangeburg](https://images.trvl-media.com/lodging/2000000/1880000/1878000/1877930/8acfa265_y.jpg) ### Spark by Hilton Orangeburg 10/10 Excellent "Yes" [](https://expedia.ca/Orangeburg-Hotels-Spark-By-Hilton-Orangeburg.h1877930.Hotel-Information) ![Comfort Inn & Suites Orangeburg](https://images.trvl-media.com/lodging/2000000/2000000/1990300/1990272/377ba79f_y.jpg) ### Comfort Inn & Suites Orangeburg 10/10 Excellent "Room was clean and very comfortable. Staff at check-in (Jordan) and in breakfast area (Geraldine) were super friendly and helpful. Only negative was I didn’t check receipt at check out and when I got home I saw a different card and card number and amount charged that did not correspond with my reservation. I will have to call and sort out this error during business hours. " [](https://expedia.ca/Orangeburg-Hotels-Comfort-Inn-Suites.h1990272.Hotel-Information) ![Days Inn by Wyndham Orangeburg](https://images.trvl-media.com/lodging/1000000/110000/100500/100411/f6e62ff1_y.jpg) ### Days Inn by Wyndham Orangeburg 10/10 Excellent "Good location clean and quiet " [](https://expedia.ca/Orangeburg-Hotels-Days-Inn-By-Wyndham-Orangeburg.h100411.Hotel-Information) ![Super 8 by Wyndham, Orangeburg](https://images.trvl-media.com/lodging/1000000/40000/34400/34400/c9ac8d21_y.jpg) ### Super 8 by Wyndham, Orangeburg 10/10 Excellent "Good rates and quiet. Great location " [](https://expedia.ca/Orangeburg-Hotels-Super-8-By-Wyndham.h34400.Hotel-Information) ![Baymont by Wyndham Orangeburg North](https://images.trvl-media.com/lodging/1000000/30000/20500/20500/3438166f_y.jpg) ### Baymont by Wyndham Orangeburg North 10/10 Excellent "The room was clean and the staff was great. We didn't do the breakfast because we didn't care for any thing they had " [](https://expedia.ca/Orangeburg-Hotels-Baymont-By-Wyndham-Orangeburg-North.h20500.Hotel-Information) ![Holiday Inn Express & Suites Orangeburg by IHG](https://images.trvl-media.com/lodging/1000000/600000/597800/597750/2e89db8e_y.jpg) ### Holiday Inn Express & Suites Orangeburg by IHG 10/10 Excellent "The room was spotless and the staff was courteous. " [](https://expedia.ca/Orangeburg-Hotels-Holiday-Inn-Express-Hotel-Suites-Orangeburg.h597750.Hotel-Information) ## Frequently asked questions ### How much do business-friendly hotels in Orangeburg cost? ### What are the best business-friendly hotels in Orangeburg? ### How many business-friendly hotels are there in Orangeburg? ### What are the top business-friendly motels in Orangeburg? ### Are there any family-friendly hotels in Orangeburg that are also business friendly? ### Why book your business-friendly hotel in Orangeburg with Expedia? ### How can I find cheap business-friendly hotels in Orangeburg? ### What is there to do in Orangeburg near my business-friendly hotel? ## Explore a world of travel with Expedia - Lodging - Flights - Packages - Cars - Vacation Rental - More ways to book - [5 Star Hotels in Norway ](https://www.expedia.ca/5Star-Norway-Hotels.s50-0-d553248634998816179.Travel-Guide-Filter-Hotels) - [Cheap Hotels in Bamberg ](https://www.expedia.ca/Bamberg-Hotels-Cheap-Hotels.0-0-d55570-tCheapHotels.Travel-Guide-Filter-Hotels) - 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