Title: Browse the Best Orangeburg County Resorts | Expedia.ca [Orangeburg County Hotels](https://expedia.ca/Destinations-In-Orangeburg-County.d553248635996998003.Hotel-Destinations)[Vacation Rentals in Orangeburg County](https://expedia.ca/Destinations-In-Orangeburg-County.d553248635996998003.Vacation-Rental-Destinations)[Orangeburg County Car Rentals](https://expedia.ca/Destinations-In-Orangeburg-County.d553248635996998003.Car-Rental-Destinations)[Orangeburg County Vacations](https://expedia.ca/Orangeburg-County.d553248635996998003.Destination-Travel-Guides) ![DEG7A9 Bald cypress forest in autumn at the Cuddo Unit of the Santee Refuge, SC.](https://images.trvl-media.com/place/9953/a26d5a16-8cd2-405d-94ab-122a2f63e661.jpg?impolicy=fcrop&w=1200&h=500&q=medium) # Search Resort Hotels in Orangeburg County ## Compare and save - ![](https://a.travel-assets.com/travel-assets-manager/pictogram-bex/light__calendar_shield.svg) ### Change your mind Book hotels with free cancellation - ![](https://a.travel-assets.com/travel-assets-manager/pictogram-bex/light__deals.svg) ### Treat yourself Sign in to save 10% or more on thousands of hotels [Sign in](https://www.expedia.ca/login) - ![](https://a.travel-assets.com/travel-assets-manager/pictogram-bex/light__bed.svg) ### Be picky Search almost a million properties worldwide ## Check prices for these dates Next weekend [Jan 2 - Jan 4](https://www.expedia.ca/Hotel-Search?regionId=553248635996998003&startDate=2026-01-02&endDate=2026-01-04&adults=2&lodging=HOTEL_RESORT&rfrr=TG.LP.CheckPrices.Hotel&openPlayBack=true) In two weeks [Jan 9 - Jan 11](https://www.expedia.ca/Hotel-Search?regionId=553248635996998003&startDate=2026-01-09&endDate=2026-01-11&adults=2&lodging=HOTEL_RESORT&rfrr=TG.LP.CheckPrices.Hotel&openPlayBack=true) In one month [Jan 23 - Jan 25](https://www.expedia.ca/Hotel-Search?regionId=553248635996998003&startDate=2026-01-23&endDate=2026-01-25&adults=2&lodging=HOTEL_RESORT&rfrr=TG.LP.CheckPrices.Hotel&openPlayBack=true) In two months [Feb 20 - Feb 22](https://www.expedia.ca/Hotel-Search?regionId=553248635996998003&startDate=2026-02-20&endDate=2026-02-22&adults=2&lodging=HOTEL_RESORT&rfrr=TG.LP.CheckPrices.Hotel&openPlayBack=true) ## Top Cities in Orangeburg County ![](https://mediaim.expedia.com/destination/2/d91715fa11e9d5570856838fd5bd4287.jpg?impolicy=fcrop&w=384&h=216&q=medium) #### Orangeburg [](https://expedia.ca/Orangeburg-Resort-Hotels.d6058108-aaResortHotels.Travel-Guide-Accommodation) ## Our top choices for Orangeburg County resorts ![Pool](https://images.trvl-media.com/lodging/103000000/102020000/102018300/102018216/fb378afa.jpg?impolicy=fcrop&w=357&h=201&p=1&q=medium) ![Property grounds](https://images.trvl-media.com/lodging/103000000/102020000/102018300/102018216/d9cffe18.jpg?impolicy=fcrop&w=357&h=201&p=1&q=medium) ![Microwave, oven, stovetop, dishwasher](https://images.trvl-media.com/lodging/103000000/102020000/102018300/102018216/bf38ce1d.jpg?impolicy=fcrop&w=357&h=201&p=1&q=medium) ![Microwave, oven, stovetop, dishwasher](https://images.trvl-media.com/lodging/103000000/102020000/102018300/102018216/d8195f71.jpg?impolicy=fcrop&w=357&h=201&p=1&q=medium) ### Waterfront Condo on Lake Marion [](https://www.expedia.ca/Santee-Hotels-Spacious-Condo-On-Beautiful-Lake-Marion.h102018216.Hotel-Information) Santee 10/10 Exceptional (6) "This place was outstanding, clean and beautifully decorated. I will rent this property again " ![United States](https://a.travel-assets.com/egds/marks/flags/us.svg) Tuwanna G. [](https://www.expedia.ca/Santee-Hotels-Spacious-Condo-On-Beautiful-Lake-Marion.h102018216.Hotel-Information) ![Interior](https://images.trvl-media.com/lodging/109000000/108970000/108963600/108963596/b1937017.jpg?impolicy=fcrop&w=357&h=201&p=1&q=medium) ![Hair dryer, towels, soap, shampoo](https://images.trvl-media.com/lodging/109000000/108970000/108963600/108963596/62c27d79.jpg?impolicy=fcrop&w=357&h=201&p=1&q=medium) ### Lake Marion 2Bed/2Bath Deluxe! [](https://www.expedia.ca/Santee-Hotels-Lake-Marion-2Bed2Bath-Deluxe.h108963596.Hotel-Information) Santee [](https://www.expedia.ca/Santee-Hotels-Lake-Marion-2Bed2Bath-Deluxe.h108963596.Hotel-Information) ![Hair dryer, towels, soap, shampoo](https://images.trvl-media.com/lodging/109000000/108970000/108964200/108964119/bcd8bf6f.jpg?impolicy=fcrop&w=357&h=201&p=1&q=medium) ### Lake Marion 3Bed/3Bath Deluxe! [](https://www.expedia.ca/Santee-Hotels-Lake-Marion-3Bed3Bath-Deluxe.h108964119.Hotel-Information) Santee [](https://www.expedia.ca/Santee-Hotels-Lake-Marion-3Bed3Bath-Deluxe.h108964119.Hotel-Information) ![Interior](https://images.trvl-media.com/lodging/109000000/108970000/108962500/108962490/5692bed0.jpg?impolicy=fcrop&w=357&h=201&p=1&q=medium) ![Hair dryer, towels, soap, shampoo](https://images.trvl-media.com/lodging/109000000/108970000/108962500/108962490/bca2cf62.jpg?impolicy=fcrop&w=357&h=201&p=1&q=medium) ### 2Bed/2Bath Deluxe at Lake Marion! [](https://www.expedia.ca/Santee-Hotels-2Bed2Bath-Deluxe-At-Lake-Marion.h108962490.Hotel-Information) Santee [](https://www.expedia.ca/Santee-Hotels-2Bed2Bath-Deluxe-At-Lake-Marion.h108962490.Hotel-Information) ![Hair dryer, towels, soap, shampoo](https://images.trvl-media.com/lodging/109000000/108970000/108963200/108963171/6008f4d4.jpg?impolicy=fcrop&w=357&h=201&p=1&q=medium) ### 3Bed/3Bath Deluxe at Lake Marion! [](https://www.expedia.ca/Santee-Hotels-3Bed3Bath-Deluxe-At-Lake-Marion.h108963171.Hotel-Information) Santee [](https://www.expedia.ca/Santee-Hotels-3Bed3Bath-Deluxe-At-Lake-Marion.h108963171.Hotel-Information) Lowest nightly price found within the past 24 hours based on a 1 night stay for 2 adults. Prices and availability subject to change. Additional terms may apply. [View all properties](https://expedia.ca/Hotel-Search?startDate=2026-01-09&endDate=2026-01-10®ionId=553248635996998003&adults=2&lodging=HOTEL_RESORT&sort=RECOMMENDED&openPlayBack=true) ![](https://a.travel-assets.com/pricing-claim/sparkle_dark.svg) Save an average of 15% on thousands of hotels when you're signed in [Sign in ](https://expedia.ca/user/signin?ckoflag=0&uurl=e3id%3Dredr%26rurl%3D%2FOrangeburg-County-Resort-Hotels.d553248635996998003-aaResortHotels.Travel-Guide-Accommodation)[ Sign up, it's free ](https://expedia.ca/signup?enable_registration=true&+=&uurl=e3id%3Dredr%26rurl%3D%2FOrangeburg-County-Resort-Hotels.d553248635996998003-aaResortHotels.Travel-Guide-Accommodation) ## Top Orangeburg County Hotel Reviews ![Hampton Inn Santee-I-95](https://images.trvl-media.com/lodging/1000000/210000/203700/203667/5f0a1276_y.jpg) ### Hampton Inn Santee-I-95 10/10 Excellent "Every thing was great. Room was clean, and employees were very friendly. Great staff !!! " [](https://expedia.ca/Orangeburg-Hotels-Hampton-Inn-Santee-I-95.h203667.Hotel-Information) ![Hampton Inn & Suites Orangeburg](https://images.trvl-media.com/lodging/10000000/9860000/9854700/9854604/637dd914_y.jpg) ### Hampton Inn & Suites Orangeburg 10/10 Excellent "The staff was exceptional and willing to take care of extra needs that went above and beyond their normal scope of duty. Amazing breakfast! FIVE STARS ALL THE WAY! " [](https://expedia.ca/Orangeburg-Hotels-Hampton-Inn-Suites-Orangeburg.h9854604.Hotel-Information) ![Comfort Inn & Suites Santee](https://images.trvl-media.com/lodging/1000000/520000/518500/518401/8e89959e_y.jpg) ### Comfort Inn & Suites Santee 10/10 Excellent "Overall nice room, friendly staff, and great breakfast. Very satisfied with my stay. " [](https://expedia.ca/Orangeburg-Hotels-Comfort-Inn-Suites-Santee.h518401.Hotel-Information) ![Tru By Hilton Santee](https://images.trvl-media.com/lodging/93000000/92610000/92601000/92600969/5c693db6_y.jpg) ### Tru By Hilton Santee 10/10 Excellent "Clean and bright. They have an area in the lobby with pool table and a few cubby holes of wooden blocks and board games for the kids. Remember Candy Land? Also, separate area off the lobby for quiet computer use. Very satisfying after a long time driving. " [](https://expedia.ca/Santee-Hotels-Tru-By-Hilton-Santee.h92600969.Hotel-Information) ![Travelodge by Wyndham Orangeburg](https://images.trvl-media.com/lodging/18000000/17390000/17380300/17380261/bfdc100f_y.jpg) ### Travelodge by Wyndham Orangeburg 10/10 Excellent "Clean room. Ample parking " [](https://expedia.ca/Orangeburg-Hotels-Travelodge-By-Wyndham-Orangeburg.h17380261.Hotel-Information) ![Tru by Hilton Orangeburg](https://images.trvl-media.com/lodging/35000000/34330000/34323400/34323336/1bbd70f5_y.jpg) ### Tru by Hilton Orangeburg 10/10 Excellent "Yes" [](https://expedia.ca/Orangeburg-Hotels-Tru-By-Hilton-Orangeburg.h34323336.Hotel-Information) ![Fairfield Inn by Marriott Orangeburg](https://images.trvl-media.com/lodging/1000000/570000/564000/563976/aa173c27_y.jpg) ### Fairfield Inn by Marriott Orangeburg 10/10 Excellent "Cleanliness and staff " [](https://expedia.ca/Orangeburg-Hotels-Fairfield-Inn-By-Marriott-Orangeburg.h563976.Hotel-Information) ![Spark by Hilton Orangeburg](https://images.trvl-media.com/lodging/2000000/1880000/1878000/1877930/8acfa265_y.jpg) ### Spark by Hilton Orangeburg 10/10 Excellent "Yes" [](https://expedia.ca/Orangeburg-Hotels-Spark-By-Hilton-Orangeburg.h1877930.Hotel-Information) ![Best Western Plus Santee Inn](https://images.trvl-media.com/lodging/1000000/30000/21900/21863/6d1459c3_y.jpg) ### Best Western Plus Santee Inn 10/10 Excellent "The staff makes you feel at home. And the place is spotless." [](https://expedia.ca/Orangeburg-Hotels-Best-Western-Plus-Santee-Inn.h21863.Hotel-Information) ## Find out more about Orangeburg County ## Orangeburg County Resorts information | Number of reviews | 6 | | ----------------- | --------- | | Accommodation | 5 Resorts | | Lowest Price | | | Highest Price | | ## Explore a world of travel with Expedia - Lodging - Flights - Packages - Cars - Vacation Rental - More ways to book - [5 Star Hotels in Norway ](https://www.expedia.ca/5Star-Norway-Hotels.s50-0-d553248634998816179.Travel-Guide-Filter-Hotels) - [Cheap Hotels in Bamberg ](https://www.expedia.ca/Bamberg-Hotels-Cheap-Hotels.0-0-d55570-tCheapHotels.Travel-Guide-Filter-Hotels) - [Family Hotels in Bamberg ](https://www.expedia.ca/Bamberg-Hotels-Family-Hotel.0-0-d55570-tFamilyHotel.Travel-Guide-Filter-Hotels) - [Luxury Hotels in Bamberg ](https://www.expedia.ca/Bamberg-Hotels-Luxury-Hotel.0-0-d55570-tLuxuryHotel.Travel-Guide-Filter-Hotels) - [Bamberg Hotels ](https://www.expedia.ca/Bamberg-Hotels.d55570.Travel-Guide-Hotels) - 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