Title: Top Guest Houses in Orangeburg County in 2026 | Expedia.ca [Orangeburg County Hotels](https://expedia.ca/Destinations-In-Orangeburg-County.d553248635996998003.Hotel-Destinations)[Vacation Rentals in Orangeburg County](https://expedia.ca/Destinations-In-Orangeburg-County.d553248635996998003.Vacation-Rental-Destinations)[Orangeburg County Car Rentals](https://expedia.ca/Destinations-In-Orangeburg-County.d553248635996998003.Car-Rental-Destinations)[Orangeburg County Vacations](https://expedia.ca/Orangeburg-County.d553248635996998003.Destination-Travel-Guides) ![The Branchville Railroad Depot is listed on the National Register of Historic Places. The front of the structure now houses a museum/shrine of railroad memorabilia, including a caboose. It is open by appointment and children are welcome. Informal tours are led by John Norris, a retired railroad company executive. Admission is free but donations toward the upkeep of the museum are appreciated. Call (803) 707-1788 for information. The rear of the structure houses the Eatery at the Depot, which serves dinners on Thursday, Friday and Saturday evenings. Reservations are recommended but not required. Call (803) 274-8001 or (803) 515-](https://images.trvl-media.com/place/3000455875/43d228a3-3ea8-4c0d-b974-e33e83be19a7.jpg?impolicy=fcrop&w=1200&h=500&q=medium) Photo by Sara Dean / Race2Beach # Guest Houses in Orangeburg County ## Compare and save - ![](https://a.travel-assets.com/travel-assets-manager/pictogram-bex/light__calendar_shield.svg) ### Change your mind Book hotels with free cancellation - ![](https://a.travel-assets.com/travel-assets-manager/pictogram-bex/light__deals.svg) ### Treat yourself Sign in to save 10% or more on thousands of hotels [Sign in](https://www.expedia.ca/login) - ![](https://a.travel-assets.com/travel-assets-manager/pictogram-bex/light__bed.svg) ### Be picky Search almost a million properties worldwide ## Check prices for these dates Next weekend [Dec 19 - Dec 21](https://www.expedia.ca/Hotel-Search?regionId=553248635996998003&startDate=2025-12-19&endDate=2025-12-21&adults=2&lodging=GUEST_HOUSE&rfrr=TG.LP.CheckPrices.Hotel&openPlayBack=true) In two weeks [Dec 26 - Dec 28](https://www.expedia.ca/Hotel-Search?regionId=553248635996998003&startDate=2025-12-26&endDate=2025-12-28&adults=2&lodging=GUEST_HOUSE&rfrr=TG.LP.CheckPrices.Hotel&openPlayBack=true) In one month [Jan 9 - Jan 11](https://www.expedia.ca/Hotel-Search?regionId=553248635996998003&startDate=2026-01-09&endDate=2026-01-11&adults=2&lodging=GUEST_HOUSE&rfrr=TG.LP.CheckPrices.Hotel&openPlayBack=true) In two months [Feb 6 - Feb 8](https://www.expedia.ca/Hotel-Search?regionId=553248635996998003&startDate=2026-02-06&endDate=2026-02-08&adults=2&lodging=GUEST_HOUSE&rfrr=TG.LP.CheckPrices.Hotel&openPlayBack=true) ## Our top choices for Orangeburg County guest houses ![Exterior](https://images.trvl-media.com/lodging/49000000/48530000/48527000/48526956/93d9ea57.jpg?impolicy=fcrop&w=357&h=201&p=1&q=medium) ![Interior](https://images.trvl-media.com/lodging/49000000/48530000/48527000/48526956/6d509944.jpg?impolicy=fcrop&w=357&h=201&p=1&q=medium) ![Interior](https://images.trvl-media.com/lodging/49000000/48530000/48527000/48526956/605660e5.jpg?impolicy=fcrop&w=357&h=201&p=1&q=medium) ![Fridge, microwave, oven, stovetop](https://images.trvl-media.com/lodging/49000000/48530000/48527000/48526956/a6eff026.jpg?impolicy=fcrop&w=357&h=201&p=1&q=medium) ### Carriage House 2-bedroom at Camellia Cottages in historic Summerville [](https://www.expedia.ca/Summerville-Hotels-Carriage-House-2-Bedroom-At-Camellia-Cottages-In-Historic-Summerville.h48526956.Hotel-Information) Summerville Historic District 10/10 Exceptional (12) "The carriage house was nicely decorated. It provided a welcoming place to relax and rest after a busy day in Charleston. The house is near I-26 exits, which makes it easy to get to your favorite places to visit, whether it is the downtown area, beaches or other interesting sites. We found it to be a great value as compared to similar hotel accommodations. We will definitely be back on our next visit to the area." ![United States](https://a.travel-assets.com/egds/marks/flags/us.svg) Bradley L. [](https://www.expedia.ca/Summerville-Hotels-Carriage-House-2-Bedroom-At-Camellia-Cottages-In-Historic-Summerville.h48526956.Hotel-Information) ![32-inch Smart TV with digital channels, TV, Netflix](https://images.trvl-media.com/lodging/78000000/77810000/77808400/77808400/2dfae28e.jpg?impolicy=fcrop&w=357&h=201&p=1&q=medium) ![32-inch Smart TV with digital channels, TV, Netflix](https://images.trvl-media.com/lodging/78000000/77810000/77808400/77808400/3af739bb.jpg?impolicy=fcrop&w=357&h=201&p=1&q=medium) ![Front of property](https://images.trvl-media.com/lodging/78000000/77810000/77808400/77808400/2fb05b7a.jpg?impolicy=fcrop&w=357&h=201&p=1&q=medium) ![View from property](https://images.trvl-media.com/lodging/78000000/77810000/77808400/77808400/f88b19b5.jpg?impolicy=fcrop&w=357&h=201&p=1&q=medium) ### Stroble Paradise [](https://www.expedia.ca/Moncks-Corner-Hotels-Stroble-Paradise.h77808400.Hotel-Information) Moncks Corner [](https://www.expedia.ca/Moncks-Corner-Hotels-Stroble-Paradise.h77808400.Hotel-Information) Lowest nightly price found within the past 24 hours based on a 1 night stay for 2 adults. Prices and availability subject to change. Additional terms may apply. [View all properties](https://expedia.ca/Hotel-Search?startDate=2025-12-26&endDate=2025-12-27®ionId=553248635996998003&adults=2&lodging=GUEST_HOUSE&sort=RECOMMENDED&openPlayBack=true) ![](https://a.travel-assets.com/pricing-claim/sparkle_dark.svg) Save an average of 15% on thousands of hotels when you're signed in [Sign in ](https://expedia.ca/user/signin?ckoflag=0&uurl=e3id%3Dredr%26rurl%3D%2FOrangeburg-County-Guest-Houses.d553248635996998003-aaGuestHouses.Travel-Guide-Accommodation)[ Sign up, it's free ](https://expedia.ca/signup?enable_registration=true&+=&uurl=e3id%3Dredr%26rurl%3D%2FOrangeburg-County-Guest-Houses.d553248635996998003-aaGuestHouses.Travel-Guide-Accommodation) ## Top Orangeburg County Hotel Reviews ![Tru by Hilton Orangeburg](https://images.trvl-media.com/lodging/35000000/34330000/34323400/34323336/1bbd70f5_y.jpg) ### Tru by Hilton Orangeburg 10/10 Excellent "Beautiful new property. Rooms are small but comfortable. " [](https://expedia.ca/Orangeburg-Hotels-Tru-By-Hilton-Orangeburg.h34323336.Hotel-Information) ![Hampton Inn & Suites Orangeburg](https://images.trvl-media.com/lodging/10000000/9860000/9854700/9854604/637dd914_y.jpg) ### Hampton Inn & Suites Orangeburg 10/10 Excellent "Beautiful " [](https://expedia.ca/Orangeburg-Hotels-Hampton-Inn-Suites-Orangeburg.h9854604.Hotel-Information) ![Fairfield Inn by Marriott Orangeburg](https://images.trvl-media.com/lodging/1000000/570000/564000/563976/aa173c27_y.jpg) ### Fairfield Inn by Marriott Orangeburg 10/10 Excellent "Breakfast was very nice" [](https://expedia.ca/Orangeburg-Hotels-Fairfield-Inn-By-Marriott-Orangeburg.h563976.Hotel-Information) ![Spark by Hilton Orangeburg](https://images.trvl-media.com/lodging/2000000/1880000/1878000/1877930/8acfa265_y.jpg) ### Spark by Hilton Orangeburg 10/10 Excellent "Great" [](https://expedia.ca/Orangeburg-Hotels-Spark-By-Hilton-Orangeburg.h1877930.Hotel-Information) ![Comfort Inn & Suites Orangeburg](https://images.trvl-media.com/lodging/2000000/2000000/1990300/1990272/377ba79f_y.jpg) ### Comfort Inn & Suites Orangeburg 10/10 Excellent "Very friendly staff at checin and at breakfast" [](https://expedia.ca/Orangeburg-Hotels-Comfort-Inn-Suites.h1990272.Hotel-Information) ![Tru By Hilton Santee](https://images.trvl-media.com/lodging/93000000/92610000/92601000/92600969/5c693db6_y.jpg) ### Tru By Hilton Santee 10/10 Excellent "We have stayed here many times and it is always great. Clean, comfy, and quiet! Plus they welcome our doggie, which is nice. Staff are friendly and very competent. " [](https://expedia.ca/Santee-Hotels-Tru-By-Hilton-Santee.h92600969.Hotel-Information) ![Travelodge by Wyndham Santee](https://images.trvl-media.com/lodging/6000000/5640000/5630800/5630775/4ab49efd_y.jpg) ### Travelodge by Wyndham Santee 10/10 Excellent "For the cost, clean and cordial check in." [](https://expedia.ca/Orangeburg-Hotels-Travelodge-By-Wyndham-Santee.h5630775.Hotel-Information) ![Hampton Inn Santee-I-95](https://images.trvl-media.com/lodging/1000000/210000/203700/203667/5f0a1276_y.jpg) ### Hampton Inn Santee-I-95 10/10 Excellent "the breakfast was fresh. handicap parking close to entry" [](https://expedia.ca/Orangeburg-Hotels-Hampton-Inn-Santee-I-95.h203667.Hotel-Information) ![Days Inn by Wyndham Orangeburg](https://images.trvl-media.com/lodging/1000000/110000/100500/100411/f6e62ff1_y.jpg) ### Days Inn by Wyndham Orangeburg 10/10 Excellent "The room was spotless, and the breakfast was excellent. The staff went out of their way to provide us with an extra service when it was needed. Will return. " [](https://expedia.ca/Orangeburg-Hotels-Days-Inn-By-Wyndham-Orangeburg.h100411.Hotel-Information) ## Find out more about Orangeburg County ## Orangeburg County Guest Houses information | Number of reviews | | | ----------------- | -------------- | | Accommodation | 2 Guest Houses | | Lowest Price | | | Highest Price | | ## Explore a world of travel with Expedia - Lodging - Flights - Packages - Cars - Vacation Rental - More ways to book - [5 Star Hotels in Norway ](https://www.expedia.ca/5Star-Norway-Hotels.s50-0-d553248634998816179.Travel-Guide-Filter-Hotels) - [Cheap Hotels in Bamberg ](https://www.expedia.ca/Bamberg-Hotels-Cheap-Hotels.0-0-d55570-tCheapHotels.Travel-Guide-Filter-Hotels) - [Family Hotels in Bamberg ](https://www.expedia.ca/Bamberg-Hotels-Family-Hotel.0-0-d55570-tFamilyHotel.Travel-Guide-Filter-Hotels) - [Luxury Hotels in Bamberg ](https://www.expedia.ca/Bamberg-Hotels-Luxury-Hotel.0-0-d55570-tLuxuryHotel.Travel-Guide-Filter-Hotels) - [Bamberg Hotels ](https://www.expedia.ca/Bamberg-Hotels.d55570.Travel-Guide-Hotels) - 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