Title: The 10 Best Hotels Near Orange County Global Medical Center, Santa Ana from CA $114 | Expedia.ca

[Santa Ana Travel Guide](https://expedia.ca/Santa-Ana.dx9267)[Vacation Rentals in Santa Ana](https://expedia.ca/Santa-Ana-Vacation-Rentals.d9267.Travel-Guide-VacationRentals)[Flights to Santa Ana](https://expedia.ca/Cheap-Flights-To-Santa-Ana.d9267.Travel-Guide-Flights)[Things to do in Santa Ana](https://expedia.ca/Things-To-Do-In-Santa-Ana.d9267.Travel-Guide-Activities)[Orange County Global Medical Center Car Rentals](https://expedia.ca/Car-Rentals-In-Orange-County-Global-Medical-Center.d553248635997986524.Car-Rental-Guide)[Orange County Global Medical Center Vacations](https://expedia.ca/Orange-County-Global-Medical-Center-Santa-Ana.d553248635997986524.Vacation-Attraction)

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## Check prices for these dates

Tonight

[Feb 3 - Feb 4](https://www.expedia.ca/Hotel-Search?regionId=553248635997986524&startDate=2026-02-03&endDate=2026-02-04&adults=2&rfrr=TG.LP.CheckPrices.Hotel&openPlayBack=true)

Tomorrow

[Feb 4 - Feb 5](https://www.expedia.ca/Hotel-Search?regionId=553248635997986524&startDate=2026-02-04&endDate=2026-02-05&adults=2&rfrr=TG.LP.CheckPrices.Hotel&openPlayBack=true)

This weekend

[Feb 6 - Feb 8](https://www.expedia.ca/Hotel-Search?regionId=553248635997986524&startDate=2026-02-06&endDate=2026-02-08&adults=2&rfrr=TG.LP.CheckPrices.Hotel&openPlayBack=true)

Next weekend

[Feb 13 - Feb 15](https://www.expedia.ca/Hotel-Search?regionId=553248635997986524&startDate=2026-02-13&endDate=2026-02-15&adults=2&rfrr=TG.LP.CheckPrices.Hotel&openPlayBack=true)

Recommended

Price (low to high)

Distance

Star rating

## Our top choices for Orange County Global Medical Center hotels

![Queen/Queen Shower Loft with Sofa Sleeper | Living area](https://images.trvl-media.com/lodging/124000000/123220000/123214200/123214172/30fa998b.jpg?impolicy=fcrop&w=357&h=201&p=1&q=medium)

![Exterior](https://images.trvl-media.com/lodging/124000000/123220000/123214200/123214172/46aa4f1f.jpg?impolicy=fcrop&w=357&h=201&p=1&q=medium)

![Exterior](https://images.trvl-media.com/lodging/124000000/123220000/123214200/123214172/b1034210.jpg?impolicy=fcrop&w=357&h=201&p=1&q=medium)

![Queen/Queen Shower Loft with Sofa Sleeper | Living area](https://images.trvl-media.com/lodging/124000000/123220000/123214200/123214172/47e677f5.jpg?impolicy=fcrop&w=357&h=201&p=1&q=medium)

### Lemon Heights Inn

[](https://www.expedia.ca/Tustin-Hotels-Lemon-Heights-Inn.h123214172.Hotel-Information)

3 km from Orange County Global Medical Center

9.8/10

Exceptional

(31 reviews)

"Check in was super quick and easy, the room was very clean, it was quiet. Great stay!"

![United States](https://a.travel-assets.com/egds/marks/flags/us.svg)

Megan

CA $117

CA $133 total

includes taxes & fees

Feb 12 - Feb 13

[](https://www.expedia.ca/Tustin-Hotels-Lemon-Heights-Inn.h123214172.Hotel-Information)

![Premium Room One Queen and One Twin Bed](https://images.trvl-media.com/lodging/100000000/99950000/99945900/99945877/59e1d2aa.jpg?impolicy=fcrop&w=357&h=201&p=1&q=medium)

![Premium Two Queen Beds Bi Level Loft](https://images.trvl-media.com/lodging/100000000/99950000/99945900/99945877/3804a524.jpg?impolicy=fcrop&w=357&h=201&p=1&q=medium)

![Free WiFi, bed sheets](https://images.trvl-media.com/lodging/100000000/99950000/99945900/99945877/ea01617a.jpg?impolicy=fcrop&w=357&h=201&p=1&q=medium)

![Outdoor pool](https://images.trvl-media.com/lodging/100000000/99950000/99945900/99945877/a055b500.jpg?impolicy=fcrop&w=357&h=201&p=1&q=medium)

### Orange Grove Inn

[](https://www.expedia.ca/Tustin-Hotels-Orange-Grove-Inn.h99945877.Hotel-Information)

3.1 km from Orange County Global Medical Center

9.2/10

Wonderful

(1,784 reviews)

"Staff was great room was clean "

![United States](https://a.travel-assets.com/egds/marks/flags/us.svg)

Lionel

CA $121

CA $137 total

includes taxes & fees

Feb 6 - Feb 7

[](https://www.expedia.ca/Tustin-Hotels-Orange-Grove-Inn.h99945877.Hotel-Information)

![Exterior](https://images.trvl-media.com/lodging/1000000/20000/16800/16703/73dfb982.jpg?impolicy=fcrop&w=357&h=201&p=1&q=medium)

![Courtyard](https://images.trvl-media.com/lodging/1000000/20000/16800/16703/0169c4c2.jpg?impolicy=fcrop&w=357&h=201&p=1&q=medium)

![Exterior](https://images.trvl-media.com/lodging/1000000/20000/16800/16703/c3f6e906.jpg?impolicy=fcrop&w=357&h=201&p=1&q=medium)

![In-room safe, desk, blackout drapes, iron/ironing board](https://images.trvl-media.com/lodging/1000000/20000/16800/16703/5829e937.jpg?impolicy=fcrop&w=357&h=201&p=1&q=medium)

### Holiday Inn Express & Suites Santa Ana - Orange County by IHG

[](https://www.expedia.ca/Santa-Ana-Hotels-Holiday-Inn-Express-And-Suites-Santa-Ana-Orange-County.h16703.Hotel-Information)

Lyon Street, 1.6 km from Orange County Global Medical Center

8.6/10

Excellent

(1,234 reviews)

"enjoyed our stay."

![United States](https://a.travel-assets.com/egds/marks/flags/us.svg)

Melissa

CA $174

CA $197 total

includes taxes & fees

Feb 8 - Feb 9

[](https://www.expedia.ca/Santa-Ana-Hotels-Holiday-Inn-Express-And-Suites-Santa-Ana-Orange-County.h16703.Hotel-Information)

![Lobby](https://images.trvl-media.com/lodging/7000000/6150000/6141900/6141877/ac1f0688.jpg?impolicy=fcrop&w=357&h=201&p=1&q=medium)

![Property amenity](https://images.trvl-media.com/lodging/7000000/6150000/6141900/6141877/8df550e2.jpg?impolicy=fcrop&w=357&h=201&p=1&q=medium)

![Meeting facility](https://images.trvl-media.com/lodging/7000000/6150000/6141900/6141877/42239132.jpg?impolicy=fcrop&w=357&h=201&p=1&q=medium)

![Exterior](https://images.trvl-media.com/lodging/7000000/6150000/6141900/6141877/d1f2e9ce.jpg?impolicy=fcrop&w=357&h=201&p=1&q=medium)

### Fairfield Inn & Suites Tustin Orange County

[](https://www.expedia.ca/Tustin-Hotels-Fairfield-Inn-Suites-Tustin-Orange-County.h6141877.Hotel-Information)

3.2 km from Orange County Global Medical Center

8.6/10

Excellent

(1,005 reviews)

"Great breakfast great location "

![United States](https://a.travel-assets.com/egds/marks/flags/us.svg)

Sergio

CA $183

CA $208 total

includes taxes & fees

Feb 6 - Feb 7

[](https://www.expedia.ca/Tustin-Hotels-Fairfield-Inn-Suites-Tustin-Orange-County.h6141877.Hotel-Information)

![Desk, blackout drapes, free WiFi, bed sheets](https://images.trvl-media.com/lodging/11000000/10560000/10553200/10553115/2f81b7dd.jpg?impolicy=fcrop&w=357&h=201&p=1&q=medium)

![Exterior](https://images.trvl-media.com/lodging/11000000/10560000/10553200/10553115/867cef21.jpg?impolicy=fcrop&w=357&h=201&p=1&q=medium)

![Desk, blackout drapes, free WiFi, bed sheets](https://images.trvl-media.com/lodging/11000000/10560000/10553200/10553115/fbf2d8a2.jpg?impolicy=fcrop&w=357&h=201&p=1&q=medium)

![Front of property](https://images.trvl-media.com/lodging/11000000/10560000/10553200/10553115/fa1f10d2.jpg?impolicy=fcrop&w=357&h=201&p=1&q=medium)

### Motel 6 Tustin, CA – Orange County

[](https://www.expedia.ca/Tustin-Hotels-Tustin-Motor-Lodge.h10553115.Hotel-Information)

2 km from Orange County Global Medical Center

8.0/10

Very good

(453 reviews)

"very clean, wifi was good, staff was very nice"

![United States](https://a.travel-assets.com/egds/marks/flags/us.svg)

Andrew

CA $115

CA $135 total

includes taxes & fees

Feb 8 - Feb 9

[](https://www.expedia.ca/Tustin-Hotels-Tustin-Motor-Lodge.h10553115.Hotel-Information)

![Standard Double Room, 2 Queen Beds](https://images.trvl-media.com/lodging/72000000/71080000/71078100/71078087/86079c81.jpg?impolicy=fcrop&w=357&h=201&p=1&q=medium)

![Standard Room](https://images.trvl-media.com/lodging/72000000/71080000/71078100/71078087/38d48539.jpg?impolicy=fcrop&w=357&h=201&p=1&q=medium)

![Interior](https://images.trvl-media.com/lodging/72000000/71080000/71078100/71078087/5089937b.jpg?impolicy=fcrop&w=357&h=201&p=1&q=medium)

![Exterior](https://images.trvl-media.com/lodging/72000000/71080000/71078100/71078087/225aaf28.jpg?impolicy=fcrop&w=357&h=201&p=1&q=medium)

### Bel Air Motor Hotel

[](https://www.expedia.ca/Tustin-Hotels-Bel-Air-Motor-Hotel.h71078087.Hotel-Information)

1.3 km from Orange County Global Medical Center

7.0/10

Good

(110 reviews)

"Excellent!"

![United States](https://a.travel-assets.com/egds/marks/flags/us.svg)

Monica

CA $115

CA $130 total

includes taxes & fees

Feb 11 - Feb 12

[](https://www.expedia.ca/Tustin-Hotels-Bel-Air-Motor-Hotel.h71078087.Hotel-Information)

![Standard Room, 1 King Bed | Living room](https://images.trvl-media.com/lodging/3000000/2220000/2210900/2210851/ad8228a2.jpg?impolicy=fcrop&w=357&h=201&p=1&q=medium)

![Exterior](https://images.trvl-media.com/lodging/3000000/2220000/2210900/2210851/6b5b8f1b.jpg?impolicy=fcrop&w=357&h=201&p=1&q=medium)

![Business centre](https://images.trvl-media.com/lodging/3000000/2220000/2210900/2210851/a3285567.jpg?impolicy=fcrop&w=357&h=201&p=1&q=medium)

![Standard Room, 1 King Bed](https://images.trvl-media.com/lodging/3000000/2220000/2210900/2210851/48b91377.jpg?impolicy=fcrop&w=357&h=201&p=1&q=medium)

### Orange Tustin Inn

[](https://www.expedia.ca/Orange-Hotels-Orange-Tustin-Inn.h2210851.Hotel-Information)

2.6 km from Orange County Global Medical Center

6.6/10

(449 reviews)

"Cheap one night"

![United States](https://a.travel-assets.com/egds/marks/flags/us.svg)

Branden

CA $158

CA $174 total

includes taxes & fees

Feb 23 - Feb 24

[](https://www.expedia.ca/Orange-Hotels-Orange-Tustin-Inn.h2210851.Hotel-Information)

![Desk, free WiFi](https://images.trvl-media.com/lodging/1000000/1000000/996400/996395/8e56ece6.jpg?impolicy=fcrop&w=357&h=201&p=1&q=medium)

![Lobby](https://images.trvl-media.com/lodging/1000000/1000000/996400/996395/62f16b29.jpg?impolicy=fcrop&w=357&h=201&p=1&q=medium)

![Exterior](https://images.trvl-media.com/lodging/1000000/1000000/996400/996395/74a49a5d.jpg?impolicy=fcrop&w=357&h=201&p=1&q=medium)

![Property grounds](https://images.trvl-media.com/lodging/1000000/1000000/996400/996395/f08d3740.jpg?impolicy=fcrop&w=357&h=201&p=1&q=medium)

### Motel 6 Santa Ana, CA

[](https://www.expedia.ca/Santa-Ana-Hotels-Motel-6-Santa-Ana.h996395.Hotel-Information)

1.4 km from Orange County Global Medical Center

7.4/10

Good

(1,000 reviews)

"Staff was nice and room was really clean"

![United States](https://a.travel-assets.com/egds/marks/flags/us.svg)

Anelyn

CA $98

CA $114 total

includes taxes & fees

Feb 9 - Feb 10

[](https://www.expedia.ca/Santa-Ana-Hotels-Motel-6-Santa-Ana.h996395.Hotel-Information)

![BBQ/picnic area](https://images.trvl-media.com/lodging/7000000/6150000/6141900/6141883/0945ca88.jpg?impolicy=fcrop&w=357&h=201&p=1&q=medium)

![Lobby](https://images.trvl-media.com/lodging/7000000/6150000/6141900/6141883/w4000h2663x0y0-279b47c3.jpg?impolicy=fcrop&w=357&h=201&p=1&q=medium)

![Lobby](https://images.trvl-media.com/lodging/7000000/6150000/6141900/6141883/f497f0d6.jpg?impolicy=fcrop&w=357&h=201&p=1&q=medium)

![TV](https://images.trvl-media.com/lodging/7000000/6150000/6141900/6141883/1aefbaa1.jpg?impolicy=fcrop&w=357&h=201&p=1&q=medium)

### Residence Inn Tustin Orange County

[](https://www.expedia.ca/Tustin-Hotels-Residence-Inn-Tustin-Orange-County.h6141883.Hotel-Information)

3.4 km from Orange County Global Medical Center

9.0/10

Wonderful

(1,003 reviews)

"Clean room, great staff, good breakfast, and reasonable parking fees "

![United States](https://a.travel-assets.com/egds/marks/flags/us.svg)

Van-Khanh

CA $196

CA $221 total

includes taxes & fees

Feb 6 - Feb 7

[](https://www.expedia.ca/Tustin-Hotels-Residence-Inn-Tustin-Orange-County.h6141883.Hotel-Information)

![Restaurant](https://images.trvl-media.com/lodging/96000000/95250000/95241100/95241034/9980cdc7.jpg?impolicy=fcrop&w=357&h=201&p=1&q=medium)

![Luxury Cottage, 2 Bedrooms | Private kitchen](https://images.trvl-media.com/lodging/96000000/95250000/95241100/95241034/91bbfe1c.jpg?impolicy=fcrop&w=357&h=201&p=1&q=medium)

![Standard Double Room, 1 King Bed](https://images.trvl-media.com/lodging/96000000/95250000/95241100/95241034/e015db70.jpg?impolicy=fcrop&w=357&h=201&p=1&q=medium)

![Luxury Cottage, 2 Bedrooms | Private kitchen](https://images.trvl-media.com/lodging/96000000/95250000/95241100/95241034/8a9bbfaf.jpg?impolicy=fcrop&w=357&h=201&p=1&q=medium)

### The Richland

[](https://www.expedia.ca/Orange-Hotels-The-Richland.h95241034.Hotel-Information)

4.3 km from Orange County Global Medical Center

9.8/10

Exceptional

(40 reviews)

"Room was spotless. We enjoyed our stay!"

![United States](https://a.travel-assets.com/egds/marks/flags/us.svg)

Jason

[](https://www.expedia.ca/Orange-Hotels-The-Richland.h95241034.Hotel-Information)

![Exterior](https://images.trvl-media.com/lodging/124000000/123340000/123334000/123333921/1b9042db.jpg?impolicy=fcrop&w=357&h=201&p=1&q=medium)

![Exterior](https://images.trvl-media.com/lodging/124000000/123340000/123334000/123333921/8b5c914f.jpg?impolicy=fcrop&w=357&h=201&p=1&q=medium)

![1 Queen Bed, Non-Smoking](https://images.trvl-media.com/lodging/124000000/123340000/123334000/123333921/7da5a151.jpg?impolicy=fcrop&w=357&h=201&p=1&q=medium)

![1 Queen Bed, Non-Smoking](https://images.trvl-media.com/lodging/124000000/123340000/123334000/123333921/5a66cffb.jpg?impolicy=fcrop&w=357&h=201&p=1&q=medium)

### Angel Motel near Anaheim 

[](https://www.expedia.ca/Orange-Hotels-Angel-Motel-Near-Anaheim.h123333921.Hotel-Information)

5.6 km from Orange County Global Medical Center

9.6/10

Exceptional

(11 reviews)

"Cómodo y cerca de Oulets de Orange y Disney "

![Mexico](https://a.travel-assets.com/egds/marks/flags/mx.svg)

Jorge

CA $116

CA $127 total

includes taxes & fees

Feb 22 - Feb 23

[](https://www.expedia.ca/Orange-Hotels-Angel-Motel-Near-Anaheim.h123333921.Hotel-Information)

![Restaurant](https://images.trvl-media.com/lodging/9000000/8430000/8427100/8427035/34cf3507.jpg?impolicy=fcrop&w=357&h=201&p=1&q=medium)

![Lobby sitting area](https://images.trvl-media.com/lodging/9000000/8430000/8427100/8427035/b0110543.jpg?impolicy=fcrop&w=357&h=201&p=1&q=medium)

![Premium bedding, down comforters, pillowtop beds, desk](https://images.trvl-media.com/lodging/9000000/8430000/8427100/8427035/e13e9152.jpg?impolicy=fcrop&w=357&h=201&p=1&q=medium)

![Lobby](https://images.trvl-media.com/lodging/9000000/8430000/8427100/8427035/e6511473.jpg?impolicy=fcrop&w=357&h=201&p=1&q=medium)

### Ayres Hotel Orange

[](https://www.expedia.ca/Orange-Hotels-Ayres-Hotel-Orange.h8427035.Hotel-Information)

6.6 km from Orange County Global Medical Center

9.6/10

Exceptional

(2,575 reviews)

"Good hot breakfast, spacious room, great staff!"

![United States](https://a.travel-assets.com/egds/marks/flags/us.svg)

Valerie

CA $174

CA $191 total

includes taxes & fees

Feb 9 - Feb 10

[](https://www.expedia.ca/Orange-Hotels-Ayres-Hotel-Orange.h8427035.Hotel-Information)

![Exterior](https://images.trvl-media.com/lodging/1000000/30000/24100/24076/d20f3331.jpg?impolicy=fcrop&w=357&h=201&p=1&q=medium)

![Exterior](https://images.trvl-media.com/lodging/1000000/30000/24100/24076/f6771788.jpg?impolicy=fcrop&w=357&h=201&p=1&q=medium)

![Lobby sitting area](https://images.trvl-media.com/lodging/1000000/30000/24100/24076/2ad2aa69.jpg?impolicy=fcrop&w=357&h=201&p=1&q=medium)

![Point of interest](https://images.trvl-media.com/lodging/1000000/30000/24100/24076/68d572c6.jpg?impolicy=fcrop&w=357&h=201&p=1&q=medium)

### Holiday Inn Santa Ana-Orange Co. Arpt by IHG

[](https://www.expedia.ca/Santa-Ana-Hotels-Holiday-Inn-Santa-Ana-Orange-County-Airport.h24076.Hotel-Information)

5.2 km from Orange County Global Medical Center

8.8/10

Excellent

(1,201 reviews)

"excellent place to stay"

![United States](https://a.travel-assets.com/egds/marks/flags/us.svg)

CRISTINA MARIE

CA $137

CA $155 total

includes taxes & fees

Feb 23 - Feb 24

[](https://www.expedia.ca/Santa-Ana-Hotels-Holiday-Inn-Santa-Ana-Orange-County-Airport.h24076.Hotel-Information)

![Lobby](https://images.trvl-media.com/lodging/1000000/20000/13000/12935/cba67fa1.jpg?impolicy=fcrop&w=357&h=201&p=1&q=medium)

![Free daily full breakfast](https://images.trvl-media.com/lodging/1000000/20000/13000/12935/1f62b634.jpg?impolicy=fcrop&w=357&h=201&p=1&q=medium)

![Pillowtop beds, desk, laptop workspace, blackout drapes](https://images.trvl-media.com/lodging/1000000/20000/13000/12935/424b2641.jpg?impolicy=fcrop&w=357&h=201&p=1&q=medium)

![Reception](https://images.trvl-media.com/lodging/1000000/20000/13000/12935/7ea2dc74.jpg?impolicy=fcrop&w=357&h=201&p=1&q=medium)

### Best Western Orange Plaza

[](https://www.expedia.ca/Orange-Hotels-Best-Western-Orange-Plaza.h12935.Hotel-Information)

4.8 km from Orange County Global Medical Center

8.8/10

Excellent

(1,001 reviews)

"Love the additional mini room with the couch and great service"

![United States](https://a.travel-assets.com/egds/marks/flags/us.svg)

clarissa

CA $135

CA $149 total

includes taxes & fees

Feb 8 - Feb 9

[](https://www.expedia.ca/Orange-Hotels-Best-Western-Orange-Plaza.h12935.Hotel-Information)

![Lobby](https://images.trvl-media.com/lodging/16000000/15400000/15399700/15399682/efd1447b.jpg?impolicy=fcrop&w=357&h=201&p=1&q=medium)

![Lobby](https://images.trvl-media.com/lodging/16000000/15400000/15399700/15399682/23206ef3.jpg?impolicy=fcrop&w=357&h=201&p=1&q=medium)

![Exterior](https://images.trvl-media.com/lodging/16000000/15400000/15399700/15399682/w3837h2557x3y3-612dc7cd.jpg?impolicy=fcrop&w=357&h=201&p=1&q=medium)

![Sport court](https://images.trvl-media.com/lodging/16000000/15400000/15399700/15399682/00a4e4db.jpg?impolicy=fcrop&w=357&h=201&p=1&q=medium)

### Homewood Suites By Hilton Irvine John Wayne Airport

[](https://www.expedia.ca/Irvine-Hotels-Homewood-Suites-By-Hilton-Irvine-John-Wayne-Airport.h15399682.Hotel-Information)

6.9 km from Orange County Global Medical Center

9.6/10

Exceptional

(1,000 reviews)

"Really enjoyed my stay here"

![United States](https://a.travel-assets.com/egds/marks/flags/us.svg)

Junu

CA $237

CA $262 total

includes taxes & fees

Feb 27 - Feb 28

[](https://www.expedia.ca/Irvine-Hotels-Homewood-Suites-By-Hilton-Irvine-John-Wayne-Airport.h15399682.Hotel-Information)

![Lobby](https://images.trvl-media.com/lodging/1000000/800000/797200/797111/76099d36.jpg?impolicy=fcrop&w=357&h=201&p=1&q=medium)

![Interior](https://images.trvl-media.com/lodging/1000000/800000/797200/797111/0f69175e.jpg?impolicy=fcrop&w=357&h=201&p=1&q=medium)

![Premium bedding, down comforters, pillowtop beds, in-room safe](https://images.trvl-media.com/lodging/1000000/800000/797200/797111/2abf864c.jpg?impolicy=fcrop&w=357&h=201&p=1&q=medium)

![Front of property](https://images.trvl-media.com/lodging/1000000/800000/797200/797111/86ca2b7e.jpg?impolicy=fcrop&w=357&h=201&p=1&q=medium)

### Ayres Hotel Anaheim

[](https://www.expedia.ca/Anaheim-Hotels-Ayres-Hotel-Anaheim.h797111.Hotel-Information)

7.1 km from Orange County Global Medical Center

9.4/10

Exceptional

(2,093 reviews)

"Great location, clean comfortable rooms and the staff is amazing. "

![United States](https://a.travel-assets.com/egds/marks/flags/us.svg)

Brian

CA $171

CA $201 total

includes taxes & fees

Feb 8 - Feb 9

[](https://www.expedia.ca/Anaheim-Hotels-Ayres-Hotel-Anaheim.h797111.Hotel-Information)

![Exterior](https://images.trvl-media.com/lodging/39000000/38760000/38750500/38750423/751a38ff.jpg?impolicy=fcrop&w=357&h=201&p=1&q=medium)

![Exterior](https://images.trvl-media.com/lodging/39000000/38760000/38750500/38750423/a2662005.jpg?impolicy=fcrop&w=357&h=201&p=1&q=medium)

![Exterior](https://images.trvl-media.com/lodging/39000000/38760000/38750500/38750423/8745794f.jpg?impolicy=fcrop&w=357&h=201&p=1&q=medium)

![Outdoor pool, open 8:00 AM to 10:00 PM, pool umbrellas, sun loungers](https://images.trvl-media.com/lodging/39000000/38760000/38750500/38750423/244d041b.jpg?impolicy=fcrop&w=357&h=201&p=1&q=medium)

### Staybridge Suites Irvine-John Wayne Airport by IHG

[](https://www.expedia.ca/Irvine-Hotels-Staybridge-Suites-Irvine.h38750423.Hotel-Information)

5.7 km from Orange County Global Medical Center

9.0/10

Wonderful

(1,002 reviews)

"Clean, rooms were perfect for a long stay, free breakfast had everything you could want to eat, staff was accommodating and friendly. Will stay here every business trip to the OC. "

![United States](https://a.travel-assets.com/egds/marks/flags/us.svg)

Carlos

CA $180

CA $213 total

includes taxes & fees

Feb 18 - Feb 19

[](https://www.expedia.ca/Irvine-Hotels-Staybridge-Suites-Irvine.h38750423.Hotel-Information)

![Lobby](https://images.trvl-media.com/lodging/1000000/10000/3600/3589/60b3aec6.jpg?impolicy=fcrop&w=357&h=201&p=1&q=medium)

![Property amenity](https://images.trvl-media.com/lodging/1000000/10000/3600/3589/ee7372c5.jpg?impolicy=fcrop&w=357&h=201&p=1&q=medium)

![Lobby](https://images.trvl-media.com/lodging/1000000/10000/3600/3589/26891f24.jpg?impolicy=fcrop&w=357&h=201&p=1&q=medium)

![Exterior](https://images.trvl-media.com/lodging/1000000/10000/3600/3589/4e4a688f.jpg?impolicy=fcrop&w=357&h=201&p=1&q=medium)

### Best Western Plus Orange County Airport North

[](https://www.expedia.ca/Santa-Ana-Hotels-Best-Western-Plus-Orange-County-Airport-North.h3589.Hotel-Information)

5.2 km from Orange County Global Medical Center

8.6/10

Excellent

(1,748 reviews)

"Clean room, friendly staff, great breakfast, plenty of parking"

![United States](https://a.travel-assets.com/egds/marks/flags/us.svg)

Candice

CA $144

CA $162 total

includes taxes & fees

Feb 17 - Feb 18

[](https://www.expedia.ca/Santa-Ana-Hotels-Best-Western-Plus-Orange-County-Airport-North.h3589.Hotel-Information)

![Breakfast and dinner served](https://images.trvl-media.com/lodging/1000000/870000/866100/866005/a168c9b8.jpg?impolicy=fcrop&w=357&h=201&p=1&q=medium)

![Premium bedding, down comforters, in-room safe, desk](https://images.trvl-media.com/lodging/1000000/870000/866100/866005/w3836h2602x4y4-ba8d518a.jpg?impolicy=fcrop&w=357&h=201&p=1&q=medium)

![Fitness facility](https://images.trvl-media.com/lodging/1000000/870000/866100/866005/w3836h2602x4y4-c06f5eea.jpg?impolicy=fcrop&w=357&h=201&p=1&q=medium)

![Meeting facility](https://images.trvl-media.com/lodging/1000000/870000/866100/866005/e7ceb559.jpg?impolicy=fcrop&w=357&h=201&p=1&q=medium)

### Hotel Zessa Orange County Airport, a DoubleTree by Hilton

[](https://www.expedia.ca/Santa-Ana-Hotels-DoubleTree-By-Hilton-Santa-Ana-Orange-County-Airport.h866005.Hotel-Information)

6.7 km from Orange County Global Medical Center

9.0/10

Wonderful

(633 reviews)

"room was clean and comfortable to stay "

![United States](https://a.travel-assets.com/egds/marks/flags/us.svg)

hien

CA $178

CA $201 total

includes taxes & fees

Feb 28 - Mar 1

[](https://www.expedia.ca/Santa-Ana-Hotels-DoubleTree-By-Hilton-Santa-Ana-Orange-County-Airport.h866005.Hotel-Information)

![Exterior](https://images.trvl-media.com/lodging/76000000/75910000/75905500/75905491/4df6e257.jpg?impolicy=fcrop&w=357&h=201&p=1&q=medium)

![Fridge, microwave, coffee/tea maker, toaster](https://images.trvl-media.com/lodging/76000000/75910000/75905500/75905491/010b95dc.jpg?impolicy=fcrop&w=357&h=201&p=1&q=medium)

![Lobby](https://images.trvl-media.com/lodging/76000000/75910000/75905500/75905491/01fea4df.jpg?impolicy=fcrop&w=357&h=201&p=1&q=medium)

![Lobby lounge](https://images.trvl-media.com/lodging/76000000/75910000/75905500/75905491/d05356e9.jpg?impolicy=fcrop&w=357&h=201&p=1&q=medium)

### Element Irvine

[](https://www.expedia.ca/Irvine-Hotels-Element-Irvine.h75905491.Hotel-Information)

7.4 km from Orange County Global Medical Center

9.2/10

Wonderful

(593 reviews)

"Great hotel, with good breakfast. "

![United States](https://a.travel-assets.com/egds/marks/flags/us.svg)

Timothy

CA $220

CA $243 total

includes taxes & fees

Feb 6 - Feb 7

[](https://www.expedia.ca/Irvine-Hotels-Element-Irvine.h75905491.Hotel-Information)

Lowest nightly price found within the past 24 hours based on a 1 night stay for 2 adults. Prices and availability subject to change. Additional terms may apply.

[View all properties](https://expedia.ca/Hotel-Search?startDate=2026-02-17&endDate=2026-02-18&regionId=553248635997986524&adults=2&sort=RECOMMENDED&openPlayBack=true)

## Top Orange County Global Medical Center Hotel Reviews

![MainStay Suites John Wayne Airport by Choice Hotels](https://images.trvl-media.com/lodging/13000000/12770000/12765600/12765572/589970fc_y.jpg)

### MainStay Suites John Wayne Airport by Choice Hotels

10/10 Excellent

"room was great! I would stay again!"

[](https://expedia.ca/Santa-Ana-Hotels-Country-Inn-Suites-By-Radisson.h12765572.Hotel-Information)

![Orange Grove Inn](https://images.trvl-media.com/lodging/100000000/99950000/99945900/99945877/ec7f970e_y.jpg)

### Orange Grove Inn

10/10 Excellent

"Wow ! What a nice hotel. Extremely clean and very affordable. Staff was great and it’s a good location.I will definitely stay here again. "

[](https://expedia.ca/Tustin-Hotels-Orange-Grove-Inn.h99945877.Hotel-Information)

![Holiday Inn Santa Ana Orange County Airport by IHG](https://images.trvl-media.com/lodging/1000000/30000/24100/24076/d20f3331_y.jpg)

### Holiday Inn Santa Ana Orange County Airport by IHG

10/10 Excellent

"Clean room "

[](https://expedia.ca/Santa-Ana-Hotels-Holiday-Inn-Santa-Ana-Orange-County-Airport.h24076.Hotel-Information)

![Best Western Plus Orange County Airport North](https://images.trvl-media.com/lodging/1000000/10000/3600/3589/4e4a688f_y.jpg)

### Best Western Plus Orange County Airport North

10/10 Excellent

"We have stayed before. Love everything."

[](https://expedia.ca/Santa-Ana-Hotels-Best-Western-Plus-Orange-County-Airport-North.h3589.Hotel-Information)

![Holiday Inn Express & Suites Santa Ana - Orange County by IHG](https://images.trvl-media.com/lodging/1000000/20000/16800/16703/2201fb1b_y.jpg)

### Holiday Inn Express & Suites Santa Ana - Orange County by IHG

10/10 Excellent

"Muy grata estancia. Limpio y su personal muy amable. "

[](https://expedia.ca/Santa-Ana-Hotels-Holiday-Inn-Express-And-Suites-Santa-Ana-Orange-County.h16703.Hotel-Information)

![Residence Inn Tustin Orange County](https://images.trvl-media.com/lodging/7000000/6150000/6141900/6141883/7a27255d_y.jpg)

### Residence Inn Tustin Orange County

10/10 Excellent

"Everything was spot on. Great staff, clean room and responded very quickly to our concern."

[](https://expedia.ca/Tustin-Hotels-Residence-Inn-Tustin-Orange-County.h6141883.Hotel-Information)

![Days Inn by Wyndham Orange Anaheim](https://images.trvl-media.com/lodging/1000000/20000/14100/14058/29a57f41_y.jpg)

### Days Inn by Wyndham Orange Anaheim

10/10 Excellent

"Yes"

[](https://expedia.ca/Orange-Hotels-Days-Inn-By-Wyndham-Orange-Anaheim.h14058.Hotel-Information)

![La Quinta Inn & Suites by Wyndham Orange County Airport](https://images.trvl-media.com/lodging/1000000/20000/19400/19370/41d3179b_y.jpg)

### La Quinta Inn & Suites by Wyndham Orange County Airport

10/10 Excellent

"wasnt too bad"

[](https://expedia.ca/Santa-Ana-Hotels-La-Quinta-Inn-Suites-By-Wyndham-Orange-County-Airport.h19370.Hotel-Information)

![Comfort Inn & Suites Orange County John Wayne Airport](https://images.trvl-media.com/lodging/1000000/30000/20700/20677/a5191d97_y.jpg)

### Comfort Inn & Suites Orange County John Wayne Airport

10/10 Excellent

"Económico y agradable "

[](https://expedia.ca/Santa-Ana-Hotels-Comfort-Inn-Suites-Orange-County-John-Wayne-Airport.h20677.Hotel-Information)

## Hotels near other Orange County Global Medical Center attractions

![Santa Ana Zoo which includes zoo animals](https://images.trvl-media.com/place/6159107/0cc8ff2b-493c-4d46-877b-ba2d30d27870.jpg)

### Santa Ana Zoo

3.7/5 (149 reviews)

Count the monkeys at this charming little zoo that promises at least 50 primates are always present.

[See properties](https://www.expedia.ca/Hotel-Search?rfrrid=TG.LP..PointOfInterests&regionId=6159107)

![Old Orange County Courthouse, dedicated in 1901, is a granite and sandstone Romanesque Revival building located in the Santa Ana Historical Downtown District.](https://images.trvl-media.com/place/6282809/0ba72c7d-bdaf-4574-bafc-41ec389ddb62.jpg)

### Old Orange County Courthouse

3.5/5 (37 reviews)

You can browse the exhibits at Old Orange County Courthouse, a museum with a story of its own, during your travels to Santa Ana. Amble around this family-friendly area's beautiful beaches or experience its entertainment choices. 

[See properties](https://www.expedia.ca/Hotel-Search?rfrrid=TG.LP..PointOfInterests&regionId=6282809)

### Cabrillo Tennis Center

Catch an event at Cabrillo Tennis Center during your trip to Santa Ana. Stroll along the beautiful beaches or visit the shops in this family-friendly area. 

[See properties](https://www.expedia.ca/Hotel-Search?rfrrid=TG.LP..PointOfInterests&regionId=941624553453510656)

### Skinsations Spa

2.6/5 (11 reviews)

You can take time to visit Skinsations Spa during your travels to Tustin. Check out the shops and top-notch restaurants in this walkable area. 

[See properties](https://www.expedia.ca/Hotel-Search?rfrrid=TG.LP..PointOfInterests&regionId=553248621532641374)

### Yost Theater

You can enjoy a show at Yost Theater during your trip to Santa Ana. 

[See properties](https://www.expedia.ca/Hotel-Search?rfrrid=TG.LP..PointOfInterests&regionId=940744743638683648)

### Santiago Park

1.0/5 (1 review)

Enjoy a trip to Santiago Park and popular activities like taking adventure tours in Santa Ana. Stroll along the beautiful beaches or experience the entertainment choices in this family-friendly area. 

[See properties](https://www.expedia.ca/Hotel-Search?rfrrid=TG.LP..PointOfInterests&regionId=6282805)

### Dr. Willella Howe-Waffle House and Medical Museum

You can spend time browsing the exhibits at Dr. Willella Howe-Waffle House and Medical Museum during your travels in Santa Ana. Stroll along the beautiful beaches or visit the shops in this family-friendly area. 

[See properties](https://www.expedia.ca/Hotel-Search?rfrrid=TG.LP..PointOfInterests&regionId=940744316671111168)

## Frequently asked questions

### What's the area like around Orange County Global Medical Center?

### What's the best hotel to stay close to Orange County Global Medical Center?

### How many hotels will I be able to find close to Orange County Global Medical Center?

### If I need to cancel the hotel reservation for my stay near Orange County Global Medical Center, will I receive a refund?

### What can I see and do near Orange County Global Medical Center?

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- [Hotels near UC Irvine Medical Center ](https://www.expedia.ca/UC-Irvine-Medical-Center-Hotels.0-l6282680-0.Travel-Guide-Filter-Hotels)

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- [Things to do in Santa Ana ](https://www.expedia.ca/Things-To-Do-In-Santa-Ana.d9267.Travel-Guide-Activities)