Title: Book the Best Odessa LUXURY Hotels - Upscale Hotels in Odessa, FL | Expedia.ca [Odessa Travel Guide](https://expedia.ca/Odessa.dx6341356)[Hotels in Odessa](https://expedia.ca/Odessa-Hotels.d6341356.Travel-Guide-Hotels)[Vacation Rentals in Odessa](https://expedia.ca/Odessa-Vacation-Rentals.d6341356.Travel-Guide-VacationRentals)[Things to do in Odessa](https://expedia.ca/Things-To-Do-In-Odessa.d6341356.Travel-Guide-Activities)[Odessa Car Rentals](https://expedia.ca/Car-Rentals-In-Odessa.d6341356.Car-Rental-Guide)[Odessa Vacation Packages](https://expedia.ca/Odessa.d6341356.Destination-Travel-Guides) ![Boat House](https://images.trvl-media.com/place/6341356/ac8131d6-5161-427a-9ef7-99d91812f516.jpg?impolicy=fcrop&w=1200&h=500&q=medium) # Find luxury hotels in Odessa, FL - ![](https://a.travel-assets.com/travel-assets-manager/pictogram-bex/light__calendar_shield.svg) ### Change your mind Book hotels with free cancellation - ![](https://a.travel-assets.com/travel-assets-manager/pictogram-bex/light__deals.svg) ### Treat yourself Sign in to save 10% or more on thousands of hotels [Sign in](https://www.expedia.ca/login) - ![](https://a.travel-assets.com/travel-assets-manager/pictogram-bex/light__bed.svg) ### Be picky Search almost a million properties worldwide ## Check availability on Odessa Luxury Hotels Tonight [Nov 7 - Nov 8](https://www.expedia.ca/Hotel-Search?regionId=6341356&startDate=2025-11-07&endDate=2025-11-08&adults=2&propertyStyle=LUXURY&rfrr=TG.LP.CheckPrices.Hotel&openPlayBack=true&travelerType=luxury_property) Tomorrow [Nov 8 - Nov 9](https://www.expedia.ca/Hotel-Search?regionId=6341356&startDate=2025-11-08&endDate=2025-11-09&adults=2&propertyStyle=LUXURY&rfrr=TG.LP.CheckPrices.Hotel&openPlayBack=true&travelerType=luxury_property) This weekend [Nov 7 - Nov 9](https://www.expedia.ca/Hotel-Search?regionId=6341356&startDate=2025-11-07&endDate=2025-11-09&adults=2&propertyStyle=LUXURY&rfrr=TG.LP.CheckPrices.Hotel&openPlayBack=true&travelerType=luxury_property) Next weekend [Nov 14 - Nov 16](https://www.expedia.ca/Hotel-Search?regionId=6341356&startDate=2025-11-14&endDate=2025-11-16&adults=2&propertyStyle=LUXURY&rfrr=TG.LP.CheckPrices.Hotel&openPlayBack=true&travelerType=luxury_property) ## Top Odessa Luxury Hotels ## Top Odessa Hotel Reviews ![Quality Inn Airport - Cruise Port](//images.trvl-media.com/lodging/1000000/10000/4500/4462/dbf70823_y.jpg) ### Quality Inn Airport - Cruise Port 10/10 Excellent "The property is amazing clean rooms great staff and great location." [](https://expedia.ca/Tampa-Hotels-Quality-Inn-Airport-Cruise-Port.h4462.Hotel-Information) ![Seminole Hard Rock Hotel & Casino Tampa](//images.trvl-media.com/lodging/2000000/1050000/1044200/1044188/6efee43c_y.jpg) ### Seminole Hard Rock Hotel & Casino Tampa 10/10 Excellent "The overall experience was enjoyable. From check-in to checkout. " [](https://expedia.ca/Tampa-Hotels-Seminole-Hard-Rock-Hotel-Casino-Tampa.h1044188.Hotel-Information) ![Hotel Tampa Riverwalk](//images.trvl-media.com/lodging/1000000/30000/22400/22354/e58c12ba_y.jpg) ### Hotel Tampa Riverwalk 10/10 Excellent "location was great! riverwalk was right downstairs. hotel proved entertainment and the area looked fantastic. helpful staff and bartenders as well." [](https://expedia.ca/Tampa-Hotels-Hotel-Tampa-Riverwalk.h22354.Hotel-Information) ![Hotel South Tampa & Suites](//images.trvl-media.com/lodging/1000000/30000/21700/21685/ebc5e46f_y.jpg) ### Hotel South Tampa & Suites 10/10 Excellent "Very good expreience" [](https://expedia.ca/Tampa-Hotels-Hotel-South-Tampa-Suites.h21685.Hotel-Information) ![Wyndham Grand Clearwater Beach](//images.trvl-media.com/lodging/16000000/15920000/15914400/15914352/3e998290_y.jpg) ### Wyndham Grand Clearwater Beach 10/10 Excellent "room was spotless view was beautiful! " [](https://expedia.ca/St-Petersburg-Clearwater-Hotels-Wyndham-Grand-Clearwater-Beach.h15914352.Hotel-Information) ![Holiday Inn Express & Suites Tampa Stadium – Airport Area by IHG](//images.trvl-media.com/lodging/1000000/10000/3600/3530/db84dfc1_y.jpg) ### Holiday Inn Express & Suites Tampa Stadium – Airport Area by IHG 10/10 Excellent "Location was excellent and the hotel was clean " [](https://expedia.ca/Tampa-Hotels-Airport-Inn.h3530.Hotel-Information) ![Hotel Alba, Tapestry Collection by Hilton](//images.trvl-media.com/lodging/1000000/20000/13800/13705/2714044c_y.jpg) ### Hotel Alba, Tapestry Collection by Hilton 10/10 Excellent "Great pro" [](https://expedia.ca/Tampa-Hotels-Hotel-Alba.h13705.Hotel-Information) ![The Westin Tampa Bay](//images.trvl-media.com/lodging/1000000/10000/1600/1557/5e6ee943_y.jpg) ### The Westin Tampa Bay 10/10 Excellent "I really enjoyed my stay. The room was spotless and smelled amazing. The hotel had a lovely smell as soon as you walk in I really love that they had their own private beach and the jet skis were fun. Will definitely be booking here in the future." [](https://expedia.ca/Tampa-Hotels-Westin-Tampa-Bay-Hotel.h1557.Hotel-Information) ![Ramada by Wyndham Tampa Westshore Airport South](//images.trvl-media.com/lodging/1000000/30000/27400/27302/cfa6c456_y.jpg) ### Ramada by Wyndham Tampa Westshore Airport South 10/10 Excellent "I thought it was delicious" [](https://expedia.ca/Tampa-Hotels-Ramada-By-Wyndham-Tampa-Airport-Westshore.h27302.Hotel-Information) ## Frequently asked questions ### Are you looking for a luxury hotel for your Odessa vacation? > Use Expedia to arrange your flight to Tampa Intl. Airport (TPA) airport or Tampa, FL (TPF-Peter O. Knight) airport, and then select from a variety of places to stay that will deliver the luxury you want. Amenities are an important consideration when you plan a vacation, so we make it easy to find what you need to make your stay special. If you want a posh hotel that has a spa, an indoor pool, or luxury bedding, Expedia can help you find the best luxury hotel experience that Odessa has to offer. Odessa has some interesting things to see and do including Crescent Lake and Keystone Lake, so you might want to take in the local sights during your visit. ### When can I expect good weather in Odessa? > Planning for the weather is a good way to make your trip to Odessa relaxing and enjoyable, especially when you're splurging. The hottest months are usually August and July with an average temp of 82°F, while the coldest months are January and February with an average of 64°F. Average annual precipitation for Odessa is 46 inches. ### What's there to see and do in Odessa? > Take in some sights and attractions while you're in Odessa by visiting Crescent Lake, Keystone Lake, and Silver Dollar Golf Club. If you have extra time while you're in the area, you might want to stop by Old McMicky's Farm and Brooker Creek Headwaters Nature Preserve. ## Explore a world of travel with Expedia - Lodging - More ways to book - [Adults Only Resorts & in Central Florida](https://www.expedia.ca/Central-Florida-Hotels-Adults-Only-Resorts.0-0-d6048177-tAdultsOnlyResorts.Travel-Guide-Filter-Hotels) - [Beach Hotel Hotels in Central Florida](https://www.expedia.ca/Central-Florida-Hotels-Beach-Hotel.0-0-d6048177-tBeachHotel.Travel-Guide-Filter-Hotels) - [Boutique Hotels in Central Florida](https://www.expedia.ca/Central-Florida-Hotels-Boutique-Hotel.0-0-d6048177-tBoutiqueHotel.Travel-Guide-Filter-Hotels) - [Golf Hotels in Central Florida](https://www.expedia.ca/Central-Florida-Hotels-Golf-Hotel.0-0-d6048177-tGolfHotel.Travel-Guide-Filter-Hotels) - [Hotels with a Lazy River in Central Florida](https://www.expedia.ca/Central-Florida-Hotels-Hotels-With-A-Lazy-River.0-0-d6048177-tHotelswithaLazyRiver.Travel-Guide-Filter-Hotels) - 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