Title: Book the Best BUSINESS Hotels in Odessa in 2026 | Expedia.ca [Odessa Travel Guide](https://expedia.ca/Odessa.dx6138)[Hotels in Odessa](https://expedia.ca/Odessa-Hotels.d6138.Travel-Guide-Hotels)[Vacation Rentals in Odessa](https://expedia.ca/Odessa-Vacation-Rentals.d6138.Travel-Guide-VacationRentals)[Flights to Odessa](https://expedia.ca/Cheap-Flights-To-Odessa.d6138.Travel-Guide-Flights)[Things to do in Odessa](https://expedia.ca/Things-To-Do-In-Odessa.d6138.Travel-Guide-Activities)[Odessa Car Rentals](https://expedia.ca/Car-Rentals-In-Odessa.d6138.Car-Rental-Guide)[Odessa Vacation Packages](https://expedia.ca/Odessa.d6138.Destination-Travel-Guides) ![](https://images.trvl-media.com/place/6138/9c97b183-fe0c-42a1-a972-9653d6de4b8a.jpg?impolicy=fcrop&w=1200&h=500&q=medium) Photo by Ed Dominguez ![](https://images.trvl-media.com/place/6138/9c97b183-fe0c-42a1-a972-9653d6de4b8a.jpg?impolicy=fcrop&w=1200&h=500&q=medium) - ![](https://a.travel-assets.com/travel-assets-manager/pictogram-bex/light__calendar_shield.svg) ### Change your mind Book hotels with free cancellation - ![](https://a.travel-assets.com/travel-assets-manager/pictogram-bex/light__deals.svg) ### Treat yourself Sign in to save 10% or more on thousands of hotels [Sign in](https://www.expedia.ca/login) - ![](https://a.travel-assets.com/travel-assets-manager/pictogram-bex/light__bed.svg) ### Be picky Search almost a million properties worldwide ## Check availability on Odessa Business Hotels Tonight [Mar 29 - Mar 30](https://www.expedia.ca/Hotel-Search?regionId=6138&startDate=2026-03-29&endDate=2026-03-30&adults=2&rfrr=TG.LP.CheckPrices.Hotel&openPlayBack=true&travelerType=business_friendly) Tomorrow [Mar 30 - Mar 31](https://www.expedia.ca/Hotel-Search?regionId=6138&startDate=2026-03-30&endDate=2026-03-31&adults=2&rfrr=TG.LP.CheckPrices.Hotel&openPlayBack=true&travelerType=business_friendly) Next weekend [Apr 3 - Apr 5](https://www.expedia.ca/Hotel-Search?regionId=6138&startDate=2026-04-03&endDate=2026-04-05&adults=2&rfrr=TG.LP.CheckPrices.Hotel&openPlayBack=true&travelerType=business_friendly) In two weeks [Apr 10 - Apr 12](https://www.expedia.ca/Hotel-Search?regionId=6138&startDate=2026-04-10&endDate=2026-04-12&adults=2&rfrr=TG.LP.CheckPrices.Hotel&openPlayBack=true&travelerType=business_friendly) ## Our top choices for Odessa business-friendly hotels ![Premium Room, 1 King Bed, Balcony | Terrace/patio](https://images.trvl-media.com/lodging/10000000/9740000/9734200/9734121/db21e120.jpg?impolicy=fcrop&w=357&h=201&p=1&q=medium) ![Fireplace](https://images.trvl-media.com/lodging/10000000/9740000/9734200/9734121/b5b00cee.jpg?impolicy=fcrop&w=357&h=201&p=1&q=medium) ![Premium Room, 1 King Bed, Pool View](https://images.trvl-media.com/lodging/10000000/9740000/9734200/9734121/2c3a59b2.jpg?impolicy=fcrop&w=357&h=201&p=1&q=medium) ![Lobby](https://images.trvl-media.com/lodging/10000000/9740000/9734200/9734121/de285e20.jpg?impolicy=fcrop&w=357&h=201&p=1&q=medium) ### MCM Elegante Hotel and Conference Center Odessa [](https://www.expedia.ca/Midland-Hotels-MCM-Elegante-Hotel-And-Conference-Center-Odessa.h9734121.Hotel-Information) Odessa 9.0/10 Wonderful (1,001 reviews) "Enjoyed the stay, friendly staff and comfortable rooms!" ![United States](https://a.travel-assets.com/egds/marks/flags/us.svg) Stacy CA $139 CA $160 total includes taxes & fees Apr 3 - Apr 4 [](https://www.expedia.ca/Midland-Hotels-MCM-Elegante-Hotel-And-Conference-Center-Odessa.h9734121.Hotel-Information) ![Lobby sitting area](https://images.trvl-media.com/lodging/1000000/20000/18600/18517/d4d3727b.jpg?impolicy=fcrop&w=357&h=201&p=1&q=medium) ![Pillowtop beds, desk, blackout drapes, iron/ironing board](https://images.trvl-media.com/lodging/1000000/20000/18600/18517/ed875c08.jpg?impolicy=fcrop&w=357&h=201&p=1&q=medium) ![Children's play area - indoor](https://images.trvl-media.com/lodging/1000000/20000/18600/18517/08c54fdc.jpg?impolicy=fcrop&w=357&h=201&p=1&q=medium) ![Lobby](https://images.trvl-media.com/lodging/1000000/20000/18600/18517/37173ade.jpg?impolicy=fcrop&w=357&h=201&p=1&q=medium) ### MCM Grande Hotel FunDome Odessa [](https://www.expedia.ca/Midland-Hotels-MCM-Grande-Hotel-FunDome-Odessa.h18517.Hotel-Information) Odessa 8.6/10 Excellent (1,377 reviews) "Great place to stay" ![United States](https://a.travel-assets.com/egds/marks/flags/us.svg) Edward CA $94 CA $109 total includes taxes & fees Apr 26 - Apr 27 [](https://www.expedia.ca/Midland-Hotels-MCM-Grande-Hotel-FunDome-Odessa.h18517.Hotel-Information) ![Lobby](https://images.trvl-media.com/lodging/37000000/36290000/36287900/36287889/973da8d2.jpg?impolicy=fcrop&w=357&h=201&p=1&q=medium) ![Reception](https://images.trvl-media.com/lodging/37000000/36290000/36287900/36287889/2f4147db.jpg?impolicy=fcrop&w=357&h=201&p=1&q=medium) ![View from property](https://images.trvl-media.com/lodging/37000000/36290000/36287900/36287889/ecb7cc81.jpg?impolicy=fcrop&w=357&h=201&p=1&q=medium) ![Lobby](https://images.trvl-media.com/lodging/37000000/36290000/36287900/36287889/8f56f0c7.jpg?impolicy=fcrop&w=357&h=201&p=1&q=medium) ### Odessa Marriott Hotel & Conference Center [](https://www.expedia.ca/Midland-Hotels-Odessa-Marriott-Hotel-Conference-Center.h36287889.Hotel-Information) Odessa 9.2/10 Wonderful (489 reviews) "great place " ![United States](https://a.travel-assets.com/egds/marks/flags/us.svg) Sam CA $247 CA $284 total includes taxes & fees Apr 11 - Apr 12 [](https://www.expedia.ca/Midland-Hotels-Odessa-Marriott-Hotel-Conference-Center.h36287889.Hotel-Information) ![Premium bedding, pillowtop beds, desk, iron/ironing board](https://images.trvl-media.com/lodging/13000000/12510000/12503300/12503223/606e0aa7.jpg?impolicy=fcrop&w=357&h=201&p=1&q=medium) ![Lobby](https://images.trvl-media.com/lodging/13000000/12510000/12503300/12503223/e8d6a360.jpg?impolicy=fcrop&w=357&h=201&p=1&q=medium) ![Free daily on-the-go breakfast](https://images.trvl-media.com/lodging/13000000/12510000/12503300/12503223/1d95e4e9.jpg?impolicy=fcrop&w=357&h=201&p=1&q=medium) ![Exterior](https://images.trvl-media.com/lodging/13000000/12510000/12503300/12503223/cac42ef6.jpg?impolicy=fcrop&w=357&h=201&p=1&q=medium) ### La Quinta Inn & Suites by Wyndham Odessa N. - Sienna Tower [](https://www.expedia.ca/Midland-Hotels-La-Quinta-Inn-Suites-By-Wyndham-Odessa-N-Sienna-Tower.h12503223.Hotel-Information) Odessa 8.4/10 Very good (634 reviews) "Clean room great staff and breakfast was simple but good!" ![United States](https://a.travel-assets.com/egds/marks/flags/us.svg) Frantarell CA $138 CA $158 total includes taxes & fees Apr 2 - Apr 3 [](https://www.expedia.ca/Midland-Hotels-La-Quinta-Inn-Suites-By-Wyndham-Odessa-N-Sienna-Tower.h12503223.Hotel-Information) ![Lobby sitting area](https://images.trvl-media.com/lodging/9000000/8390000/8387100/8387041/5d4d732c.jpg?impolicy=fcrop&w=357&h=201&p=1&q=medium) ![Property amenity](https://images.trvl-media.com/lodging/9000000/8390000/8387100/8387041/458000b0.jpg?impolicy=fcrop&w=357&h=201&p=1&q=medium) ![Pillowtop beds, desk, laptop workspace, iron/ironing board](https://images.trvl-media.com/lodging/9000000/8390000/8387100/8387041/e6667d02.jpg?impolicy=fcrop&w=357&h=201&p=1&q=medium) ![Fitness facility](https://images.trvl-media.com/lodging/9000000/8390000/8387100/8387041/68365cf6.jpg?impolicy=fcrop&w=357&h=201&p=1&q=medium) ### Baymont by Wyndham Odessa [](https://www.expedia.ca/Midland-Hotels-Baymont-By-Wyndham-Odessa.h8387041.Hotel-Information) Odessa 8.4/10 Very good (1,325 reviews) "Great place to stay!!" ![United States](https://a.travel-assets.com/egds/marks/flags/us.svg) Steve CA $107 CA $124 total includes taxes & fees Apr 5 - Apr 6 [](https://www.expedia.ca/Midland-Hotels-Baymont-By-Wyndham-Odessa.h8387041.Hotel-Information) ![Lobby](https://images.trvl-media.com/lodging/7000000/6130000/6129400/6129384/b1d8c6cb.jpg?impolicy=fcrop&w=357&h=201&p=1&q=medium) ![Reception](https://images.trvl-media.com/lodging/7000000/6130000/6129400/6129384/2ded8869.jpg?impolicy=fcrop&w=357&h=201&p=1&q=medium) ![Exterior](https://images.trvl-media.com/lodging/7000000/6130000/6129400/6129384/94a8f91e.jpg?impolicy=fcrop&w=357&h=201&p=1&q=medium) ![Pillowtop beds, desk, laptop workspace, soundproofing](https://images.trvl-media.com/lodging/7000000/6130000/6129400/6129384/ed7596b5.jpg?impolicy=fcrop&w=357&h=201&p=1&q=medium) ### Best Western Plus North Odessa Inn & Suites [](https://www.expedia.ca/Midland-Hotels-Best-Western-Plus-North-Odessa-Inn-Suites.h6129384.Hotel-Information) Odessa 9.0/10 Wonderful (625 reviews) "The staff was very friendly and helpful. The room was clean and the breakfast had many choices! We would stay there again." ![United States](https://a.travel-assets.com/egds/marks/flags/us.svg) Gina CA $121 CA $139 total includes taxes & fees Apr 5 - Apr 6 [](https://www.expedia.ca/Midland-Hotels-Best-Western-Plus-North-Odessa-Inn-Suites.h6129384.Hotel-Information) ![Seasonal outdoor pool, open 7:00 AM to 10:00 PM, sun loungers](https://images.trvl-media.com/lodging/38000000/37990000/37983200/37983198/579a433d.jpg?impolicy=fcrop&w=357&h=201&p=1&q=medium) ![BBQ/picnic area](https://images.trvl-media.com/lodging/38000000/37990000/37983200/37983198/48128a70.jpg?impolicy=fcrop&w=357&h=201&p=1&q=medium) ![Lobby](https://images.trvl-media.com/lodging/38000000/37990000/37983200/37983198/2c6c5015.jpg?impolicy=fcrop&w=357&h=201&p=1&q=medium) ![Free daily full breakfast](https://images.trvl-media.com/lodging/38000000/37990000/37983200/37983198/6a321775.jpg?impolicy=fcrop&w=357&h=201&p=1&q=medium) ### Hawthorn Extended Stay by Wyndham Odessa [](https://www.expedia.ca/Midland-Hotels-Hawthorn-Suites-By-Wyndham-Odessa.h37983198.Hotel-Information) Odessa 8.6/10 Excellent (282 reviews) "Clean friendly " ![United States](https://a.travel-assets.com/egds/marks/flags/us.svg) Earl CA $124 CA $142 total includes taxes & fees Apr 3 - Apr 4 [](https://www.expedia.ca/Midland-Hotels-Hawthorn-Suites-By-Wyndham-Odessa.h37983198.Hotel-Information) ![Exterior](https://images.trvl-media.com/lodging/3000000/2340000/2333500/2333436/6ab1944d.jpg?impolicy=fcrop&w=357&h=201&p=1&q=medium) ![Standard Room, 1 King Bed (Extra Floor Space)](https://images.trvl-media.com/lodging/3000000/2340000/2333500/2333436/7f2ccbb9.jpg?impolicy=fcrop&w=357&h=201&p=1&q=medium) ![Breakfast meal](https://images.trvl-media.com/lodging/3000000/2340000/2333500/2333436/e4cc3ece.jpg?impolicy=fcrop&w=357&h=201&p=1&q=medium) ![Exterior](https://images.trvl-media.com/lodging/3000000/2340000/2333500/2333436/fd69e1f3.jpg?impolicy=fcrop&w=357&h=201&p=1&q=medium) ### Holiday Inn Express Hotel & Suites Odessa by IHG [](https://www.expedia.ca/Midland-Hotels-Holiday-Inn-Express-Hotel-Suites-Odessa.h2333436.Hotel-Information) Odessa 8.8/10 Excellent (415 reviews) "Clean great staff awesome breakfast " ![United States](https://a.travel-assets.com/egds/marks/flags/us.svg) Nancy CA $140 CA $161 total includes taxes & fees Apr 2 - Apr 3 [](https://www.expedia.ca/Midland-Hotels-Holiday-Inn-Express-Hotel-Suites-Odessa.h2333436.Hotel-Information) ![Reception](https://images.trvl-media.com/lodging/1000000/980000/971900/971866/493fc153.jpg?impolicy=fcrop&w=357&h=201&p=1&q=medium) ![Outdoor pool](https://images.trvl-media.com/lodging/1000000/980000/971900/971866/0b13781a.jpg?impolicy=fcrop&w=357&h=201&p=1&q=medium) ![Room, 2 Queen Beds, Non Smoking](https://images.trvl-media.com/lodging/1000000/980000/971900/971866/13192140.jpg?impolicy=fcrop&w=357&h=201&p=1&q=medium) ![Exterior](https://images.trvl-media.com/lodging/1000000/980000/971900/971866/71b4c0c2.jpg?impolicy=fcrop&w=357&h=201&p=1&q=medium) ### Hampton Inn by Hilton Odessa [](https://www.expedia.ca/Midland-Hotels-Hampton-Inn-Odessa.h971866.Hotel-Information) Odessa 8.6/10 Excellent (374 reviews) "Good stay" ![United States](https://a.travel-assets.com/egds/marks/flags/us.svg) Jesus CA $125 CA $146 total includes taxes & fees Apr 11 - Apr 12 [](https://www.expedia.ca/Midland-Hotels-Hampton-Inn-Odessa.h971866.Hotel-Information) ![Desk, iron/ironing board, free WiFi, bed sheets](https://images.trvl-media.com/lodging/1000000/980000/970800/970794/ec57d928.jpg?impolicy=fcrop&w=357&h=201&p=1&q=medium) ![Exterior](https://images.trvl-media.com/lodging/1000000/980000/970800/970794/c19e2134.jpg?impolicy=fcrop&w=357&h=201&p=1&q=medium) ![Free daily on-the-go breakfast](https://images.trvl-media.com/lodging/1000000/980000/970800/970794/8e8ad42a.jpg?impolicy=fcrop&w=357&h=201&p=1&q=medium) ![Lobby](https://images.trvl-media.com/lodging/1000000/980000/970800/970794/a74e6d04.jpg?impolicy=fcrop&w=357&h=201&p=1&q=medium) ### Comfort Suites Odessa near University [](https://www.expedia.ca/Midland-Hotels-Comfort-Suites-Odessa.h970794.Hotel-Information) Odessa 8.2/10 Very good (638 reviews) "Most comfortable bed ever" ![United States](https://a.travel-assets.com/egds/marks/flags/us.svg) Brianna CA $124 CA $142 total includes taxes & fees Apr 5 - Apr 6 [](https://www.expedia.ca/Midland-Hotels-Comfort-Suites-Odessa.h970794.Hotel-Information) Lowest nightly price found within the past 24 hours based on a 1 night stay for 2 adults. Prices and availability subject to change. Additional terms may apply. [View all properties](https://expedia.ca/Hotel-Search?startDate=2026-04-12&endDate=2026-04-13®ionId=6138&adults=2&travelerType=business_friendly&sort=RECOMMENDED&openPlayBack=true) ## Top Odessa Hotel Reviews ![Sonesta Essential Hotels Odessa](https://images.trvl-media.com/lodging/4000000/3020000/3018400/3018314/5a4da55f_y.jpg) ### Sonesta Essential Hotels Odessa 8/10 Good "Friendly staff " [](https://expedia.ca/Midland-Hotels-Super-8-By-Wyndham-Odessa-TX.h3018314.Hotel-Information) ![MCM Elegante Hotel and Conference Center Odessa](https://images.trvl-media.com/lodging/10000000/9740000/9734200/9734121/db21e120_y.jpg) ### MCM Elegante Hotel and Conference Center Odessa 10/10 Excellent "The hotel in general was very clean and the rooms were nice and clean. The breakfast was very tasty nice and warm. The staff that we encountered were friendly" [](https://expedia.ca/Midland-Hotels-MCM-Elegante-Hotel-And-Conference-Center-Odessa.h9734121.Hotel-Information) ![Quality Inn Odessa near University](https://images.trvl-media.com/lodging/12000000/11250000/11244300/11244225/ec1392f3_y.jpg) ### Quality Inn Odessa near University 6/10 Okay "I booked a studio with a kitchenette. There were hot" [](https://expedia.ca/Midland-Hotels-Parkway-Inn.h11244225.Hotel-Information) ![Holiday Inn Odessa by IHG](https://images.trvl-media.com/lodging/2000000/1660000/1652900/1652839/c51ad69d_y.jpg) ### Holiday Inn Odessa by IHG 10/10 Excellent "Easy place to stay in Odessa" [](https://expedia.ca/Midland-Hotels-Holiday-Inn-Odessa.h1652839.Hotel-Information) ![MCM Grande Hotel FunDome Odessa](https://images.trvl-media.com/lodging/1000000/20000/18600/18517/d4d3727b_y.jpg) ### MCM Grande Hotel FunDome Odessa 8/10 Good "Breakfast was the best over all" [](https://expedia.ca/Midland-Hotels-MCM-Grande-Hotel-FunDome-Odessa.h18517.Hotel-Information) ![Comfort Suites Odessa near University](https://images.trvl-media.com/lodging/1000000/980000/970800/970794/ec57d928_y.jpg) ### Comfort Suites Odessa near University 4/10 Poor "Parking is horrible. Room was not cleaned properly. Staff not friendly. Unknown charge on my cc after leaving. " [](https://expedia.ca/Midland-Hotels-Comfort-Suites-Odessa.h970794.Hotel-Information) ![Baymont by Wyndham Odessa](https://images.trvl-media.com/lodging/9000000/8390000/8387100/8387041/5d4d732c_y.jpg) ### Baymont by Wyndham Odessa 6/10 Okay "Stepped on someone's broken of nail on the floor in the room. Only coffee or milk with breakfast, no juices. No parking, lots of trucks. Tub slippery when showering." [](https://expedia.ca/Midland-Hotels-Baymont-By-Wyndham-Odessa.h8387041.Hotel-Information) ![La Quinta Inn by Wyndham Odessa](https://images.trvl-media.com/lodging/1000000/30000/25600/25599/e22f43b3_y.jpg) ### La Quinta Inn by Wyndham Odessa 4/10 Poor "Pretty tired condition, bathroom fan sounded like a tractor, ice machine broken and no other option. The breakfast was ok." [](https://expedia.ca/Midland-Hotels-La-Quinta-Inn-By-Wyndham-Odessa.h25599.Hotel-Information) ![Howard Johnson by Wyndham Odessa TX](https://images.trvl-media.com/lodging/8000000/7090000/7084000/7083936/88c3b3ad_y.jpg) ### Howard Johnson by Wyndham Odessa TX 2/10 Terrible "⭐ 1 Star – Disgusting Conditions & Requesting Refund I had a very concerning experience at this hotel and am requesting a full refund. At first, the room didn’t look obviously dirty, but there was a strong, unpleasant smell as soon as I walked in. After spending time in the room, I started experiencing intense itching and what felt like pin-needle bites all over my body. Even after leaving, the symptoms continued, and I’ve had to seek medical attention to figure out what I was exposed to—likely from the mattress or room. Looking more closely, the condition of the room was unacceptable: Cracked and damaged ceiling Rust and grime on bathroom fixtures Stained, deteriorating walls Dirty microwave with food residue still inside This is not just about cleanliness—it’s a serious health concern. I did not receive the quality or safety I paid for. I have requested a refund due to these conditions and the impact this stay has had on my health. I strongly advise others to avoid this hotel until these issues are properly addressed. " [](https://expedia.ca/Midland-Hotels-Motel-One.h7083936.Hotel-Information) ## Frequently asked questions ### How much do business-friendly hotels in Odessa cost? ### What are the best business-friendly hotels in Odessa? ### How many business-friendly hotels are there in Odessa? ### What are the best cheap business-friendly hotels in Odessa? ### What are the top business-friendly motels in Odessa? ### Are there any family-friendly hotels in Odessa that are also business friendly? ### Why book your business-friendly hotel in Odessa with Expedia? ### How can I find cheap business-friendly hotels in Odessa? ### What is there to do in Odessa near my business-friendly hotel? ## Explore a world of travel with Expedia - Lodging - Flights - Cars - More ways to book - [Business Hotels in Club Estates ](https://www.expedia.ca/Club-Estates-Midland-Hotels-Business-Hotel.0-n553248635976659210-0-tBusinessHotel.Travel-Guide-Filter-Hotels) - [Pet-Friendly Hotels in Club Estates ](https://www.expedia.ca/Club-Estates-Midland-Hotels-Pet-Friendly-Hotel.0-n553248635976659210-0-tPetfriendlyHotel.Travel-Guide-Filter-Hotels) - 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