Title: Book the Best Northwest San Antonio LUXURY Hotels - Upscale Hotels in Northwest San Antonio, TX | Expedia.ca

[Northwest San Antonio Travel Guide](https://expedia.ca/Northwest-San-Antonio.dx6059170)[Hotels in Northwest San Antonio](https://expedia.ca/Northwest-San-Antonio-Hotels.d6059170.Travel-Guide-Hotels)[Vacation Rentals in Northwest San Antonio](https://expedia.ca/Northwest-San-Antonio-Vacation-Rentals.d6059170.Travel-Guide-VacationRentals)[Flights to Northwest San Antonio](https://expedia.ca/Cheap-Flights-To-Northwest-San-Antonio.d6059170.Travel-Guide-Flights)[Things to do in Northwest San Antonio](https://expedia.ca/Things-To-Do-In-Northwest-San-Antonio.d6059170.Travel-Guide-Activities)[Northwest San Antonio Car Rentals](https://expedia.ca/Car-Rentals-In-Northwest-San-Antonio.d6059170.Car-Rental-Guide)[Northwest San Antonio Vacation Packages](https://expedia.ca/Northwest-San-Antonio.d6059170.Destination-Travel-Guides)

![Roller Coaster](https://images.trvl-media.com/place/502602/9aaf48be-94fb-4cf1-b3fd-b5ed3097ae79.jpg?impolicy=fcrop&w=1200&h=500&q=medium)

![](https://images.trvl-media.com/place/502602/9aaf48be-94fb-4cf1-b3fd-b5ed3097ae79.jpg?impolicy=fcrop&w=1200&h=500&q=medium)

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## Check availability on Northwest San Antonio Luxury Hotels

Tonight

[Jan 26 - Jan 27](https://www.expedia.ca/Hotel-Search?regionId=6059170&startDate=2026-01-26&endDate=2026-01-27&adults=2&propertyStyle=LUXURY&rfrr=TG.LP.CheckPrices.Hotel&openPlayBack=true&travelerType=luxury_property)

Tomorrow

[Jan 27 - Jan 28](https://www.expedia.ca/Hotel-Search?regionId=6059170&startDate=2026-01-27&endDate=2026-01-28&adults=2&propertyStyle=LUXURY&rfrr=TG.LP.CheckPrices.Hotel&openPlayBack=true&travelerType=luxury_property)

This weekend

[Jan 30 - Feb 1](https://www.expedia.ca/Hotel-Search?regionId=6059170&startDate=2026-01-30&endDate=2026-02-01&adults=2&propertyStyle=LUXURY&rfrr=TG.LP.CheckPrices.Hotel&openPlayBack=true&travelerType=luxury_property)

Next weekend

[Feb 6 - Feb 8](https://www.expedia.ca/Hotel-Search?regionId=6059170&startDate=2026-02-06&endDate=2026-02-08&adults=2&propertyStyle=LUXURY&rfrr=TG.LP.CheckPrices.Hotel&openPlayBack=true&travelerType=luxury_property)

## Our top choices for Northwest San Antonio luxury hotels

![Lobby](https://images.trvl-media.com/lodging/5000000/4920000/4919800/4919718/d38f20a3.jpg?impolicy=fcrop&w=357&h=201&p=1&q=medium)

![Indoor pool, 2 outdoor pools, cabanas (surcharge), sun loungers](https://images.trvl-media.com/lodging/5000000/4920000/4919800/4919718/8185b422.jpg?impolicy=fcrop&w=357&h=201&p=1&q=medium)

![Restaurant](https://images.trvl-media.com/lodging/5000000/4920000/4919800/4919718/949ee0e1.jpg?impolicy=fcrop&w=357&h=201&p=1&q=medium)

![Restaurant](https://images.trvl-media.com/lodging/5000000/4920000/4919800/4919718/6aca3bae.jpg?impolicy=fcrop&w=357&h=201&p=1&q=medium)

### Bluegreen Vacations Eilan Hotel and Spa, an Ascend Collection Resort

[](https://www.expedia.ca/San-Antonio-Hotels-Eilan-Hotel-And-Spa.h4919718.Hotel-Information)

La Cantera District

8.4/10

Very good

(1,000 reviews)

"Great place. "

![United States](https://a.travel-assets.com/egds/marks/flags/us.svg)

Charles

CA $155

CA $223 total

includes taxes & fees

Feb 4 - Feb 5

[](https://www.expedia.ca/San-Antonio-Hotels-Eilan-Hotel-And-Spa.h4919718.Hotel-Information)

![5 outdoor pools, a heated pool, cabanas (surcharge), pool umbrellas](https://images.trvl-media.com/lodging/1000000/290000/284400/284306/w3840h2556x0y4-935acc4f.jpg?impolicy=fcrop&w=357&h=201&p=1&q=medium)

![Meeting facility](https://images.trvl-media.com/lodging/1000000/290000/284400/284306/w3837h2555x3y3-735de940.jpg?impolicy=fcrop&w=357&h=201&p=1&q=medium)

![Couples treatment rooms, sauna, hot tub, steam room, body treatments](https://images.trvl-media.com/lodging/1000000/290000/284400/284306/w3837h2549x3y3-a19f857c.jpg?impolicy=fcrop&w=357&h=201&p=1&q=medium)

![Couples treatment rooms, sauna, hot tub, steam room, body treatments](https://images.trvl-media.com/lodging/1000000/290000/284400/284306/w3837h2559x3y3-1eaafa8d.jpg?impolicy=fcrop&w=357&h=201&p=1&q=medium)

### Signia by Hilton La Cantera Resort & Spa

[](https://www.expedia.ca/San-Antonio-Hotels-Signia-By-Hilton-La-Cantera-Resort-Spa.h284306.Hotel-Information)

La Cantera District

9.0/10

Wonderful

(1,019 reviews)

"Beautiful property and 5-star staff/service. "

![United States](https://a.travel-assets.com/egds/marks/flags/us.svg)

Isil

CA $344

CA $495 total

includes taxes & fees

Feb 15 - Feb 16

[](https://www.expedia.ca/San-Antonio-Hotels-Signia-By-Hilton-La-Cantera-Resort-Spa.h284306.Hotel-Information)

![Indoor pool, outdoor pool](https://images.trvl-media.com/lodging/1000000/10000/3200/3187/b99867e6.jpg?impolicy=fcrop&w=357&h=201&p=1&q=medium)

![Meeting facility](https://images.trvl-media.com/lodging/1000000/10000/3200/3187/416e70de.jpg?impolicy=fcrop&w=357&h=201&p=1&q=medium)

![Exterior](https://images.trvl-media.com/lodging/1000000/10000/3200/3187/5bddef0d.jpg?impolicy=fcrop&w=357&h=201&p=1&q=medium)

![Meeting facility](https://images.trvl-media.com/lodging/1000000/10000/3200/3187/54fbc661.jpg?impolicy=fcrop&w=357&h=201&p=1&q=medium)

### The Westin San Antonio North

[](https://www.expedia.ca/San-Antonio-Hotels-Omni-San-Antonio-Hotel-At-The-Colonnade.h3187.Hotel-Information)

Vance Jackson

8.6/10

Excellent

(1,266 reviews)

"Clean room n courteous staff Indoor n outdoor pool"

![United States](https://a.travel-assets.com/egds/marks/flags/us.svg)

Richard

CA $131

CA $158 total

includes taxes & fees

Jan 29 - Jan 30

[](https://www.expedia.ca/San-Antonio-Hotels-Omni-San-Antonio-Hotel-At-The-Colonnade.h3187.Hotel-Information)

![Outdoor pool](https://images.trvl-media.com/lodging/10000000/9330000/9330000/9329921/a5ac356f.jpg?impolicy=fcrop&w=357&h=201&p=1&q=medium)

![Exterior](https://images.trvl-media.com/lodging/10000000/9330000/9330000/9329921/477a2958.jpg?impolicy=fcrop&w=357&h=201&p=1&q=medium)

![Pillowtop beds, in-room safe, desk, blackout drapes](https://images.trvl-media.com/lodging/10000000/9330000/9330000/9329921/223492d8.jpg?impolicy=fcrop&w=357&h=201&p=1&q=medium)

![Exterior](https://images.trvl-media.com/lodging/10000000/9330000/9330000/9329921/a92bc437.jpg?impolicy=fcrop&w=357&h=201&p=1&q=medium)

### Holiday Inn Express & Suites San Antonio Medical-Six Flags by IHG

[](https://www.expedia.ca/San-Antonio-Hotels-Holiday-Inn-Express-Suites-San-Antonio-Medical-Six-Flags.h9329921.Hotel-Information)

Northwest Side

7.8/10

Good

(1,063 reviews)

"Great staying there !"

![United States](https://a.travel-assets.com/egds/marks/flags/us.svg)

Angelica

CA $129

CA $152 total

includes taxes & fees

Jan 29 - Jan 30

[](https://www.expedia.ca/San-Antonio-Hotels-Holiday-Inn-Express-Suites-San-Antonio-Medical-Six-Flags.h9329921.Hotel-Information)

![Lobby](https://images.trvl-media.com/lodging/3000000/2230000/2220400/2220322/065f54d0.jpg?impolicy=fcrop&w=357&h=201&p=1&q=medium)

![Indoor pool](https://images.trvl-media.com/lodging/3000000/2230000/2220400/2220322/ec04d75a.jpg?impolicy=fcrop&w=357&h=201&p=1&q=medium)

![In-room safe, desk, blackout drapes, iron/ironing board](https://images.trvl-media.com/lodging/3000000/2230000/2220400/2220322/ed67c17c.jpg?impolicy=fcrop&w=357&h=201&p=1&q=medium)

![Exterior](https://images.trvl-media.com/lodging/3000000/2230000/2220400/2220322/1bfd1013.jpg?impolicy=fcrop&w=357&h=201&p=1&q=medium)

### Sleep Inn & Suites at Six Flags

[](https://www.expedia.ca/San-Antonio-Hotels-Sleep-Inn-Suites-At-Six-Flags.h2220322.Hotel-Information)

Northwest Side

7.8/10

Good

(1,003 reviews)

"A great location and loved that it had a back way to get around all the construction "

![United States](https://a.travel-assets.com/egds/marks/flags/us.svg)

Cristina

CA $78

CA $91 total

includes taxes & fees

Jan 29 - Jan 30

[](https://www.expedia.ca/San-Antonio-Hotels-Sleep-Inn-Suites-At-Six-Flags.h2220322.Hotel-Information)

![Outdoor pool](https://images.trvl-media.com/lodging/2000000/1470000/1465500/1465404/67193bbc.jpg?impolicy=fcrop&w=357&h=201&p=1&q=medium)

![Jetted tub](https://images.trvl-media.com/lodging/2000000/1470000/1465500/1465404/1dc39474.jpg?impolicy=fcrop&w=357&h=201&p=1&q=medium)

![Interior](https://images.trvl-media.com/lodging/2000000/1470000/1465500/1465404/f80fef97.jpg?impolicy=fcrop&w=357&h=201&p=1&q=medium)

![Courtyard](https://images.trvl-media.com/lodging/2000000/1470000/1465500/1465404/284d6217.jpg?impolicy=fcrop&w=357&h=201&p=1&q=medium)

### Howard Johnson by Wyndham San Antonio/NW Medical Center

[](https://www.expedia.ca/San-Antonio-Hotels-Howard-Johnson-By-Wyndham-San-AntonioNW-Medical-Center.h1465404.Hotel-Information)

Balcones Heights

6.8/10

(1,002 reviews)

"Dirty walls. Black mold on mini fridge. Stains on sofa bed. Stains on the mattresses of the beds. "

![United States](https://a.travel-assets.com/egds/marks/flags/us.svg)

Anonymous traveller

[](https://www.expedia.ca/San-Antonio-Hotels-Howard-Johnson-By-Wyndham-San-AntonioNW-Medical-Center.h1465404.Hotel-Information)

![Free daily self-serve breakfast](https://images.trvl-media.com/lodging/1000000/50000/41300/41271/8db3c38d.jpg?impolicy=fcrop&w=357&h=201&p=1&q=medium)

![Pillowtop beds, in-room safe, blackout drapes, iron/ironing board](https://images.trvl-media.com/lodging/1000000/50000/41300/41271/9e3e8920.jpg?impolicy=fcrop&w=357&h=201&p=1&q=medium)

![Lobby](https://images.trvl-media.com/lodging/1000000/50000/41300/41271/b25710dc.jpg?impolicy=fcrop&w=357&h=201&p=1&q=medium)

![Exterior](https://images.trvl-media.com/lodging/1000000/50000/41300/41271/b607efdd.jpg?impolicy=fcrop&w=357&h=201&p=1&q=medium)

### Spark By Hilton San Antonio Northwest near Six Flags

[](https://www.expedia.ca/San-Antonio-Hotels-Quality-Inn-San-Antonio-Fiesta-At-Six-Flags.h41271.Hotel-Information)

La Cantera District

8.0/10

Very good

(1,928 reviews)

"Clean rooms, good location, friendly staff"

![United States](https://a.travel-assets.com/egds/marks/flags/us.svg)

APRIL

CA $81

CA $97 total

includes taxes & fees

Feb 1 - Feb 2

[](https://www.expedia.ca/San-Antonio-Hotels-Quality-Inn-San-Antonio-Fiesta-At-Six-Flags.h41271.Hotel-Information)

![Lobby sitting area](https://images.trvl-media.com/lodging/2000000/1180000/1174100/1174009/44e1c752.jpg?impolicy=fcrop&w=357&h=201&p=1&q=medium)

![Premium Room, 1 King Bed with Sofa bed, Non Smoking](https://images.trvl-media.com/lodging/2000000/1180000/1174100/1174009/340f3520.jpg?impolicy=fcrop&w=357&h=201&p=1&q=medium)

![Lobby sitting area](https://images.trvl-media.com/lodging/2000000/1180000/1174100/1174009/d27582bc.jpg?impolicy=fcrop&w=357&h=201&p=1&q=medium)

![Front of property](https://images.trvl-media.com/lodging/2000000/1180000/1174100/1174009/2da07b84.jpg?impolicy=fcrop&w=357&h=201&p=1&q=medium)

### University Inn & Suites San Antonio

[](https://www.expedia.ca/San-Antonio-Hotels-University-Inn-Suites-San-Antonio.h1174009.Hotel-Information)

Northwest Side

7.4/10

Good

(1,003 reviews)

"The staff was excellent and the rooms clean "

![United States](https://a.travel-assets.com/egds/marks/flags/us.svg)

Maria

CA $69

CA $81 total

includes taxes & fees

Jan 28 - Jan 29

[](https://www.expedia.ca/San-Antonio-Hotels-University-Inn-Suites-San-Antonio.h1174009.Hotel-Information)

![Vending machine](https://images.trvl-media.com/lodging/2000000/1620000/1614000/1613977/aa320455.jpg?impolicy=fcrop&w=357&h=201&p=1&q=medium)

![Front of property](https://images.trvl-media.com/lodging/2000000/1620000/1614000/1613977/w9000h6173x0y15-23603cae.jpg?impolicy=fcrop&w=357&h=201&p=1&q=medium)

![Lobby](https://images.trvl-media.com/lodging/2000000/1620000/1614000/1613977/ded9f09f.jpg?impolicy=fcrop&w=357&h=201&p=1&q=medium)

![Outdoor pool](https://images.trvl-media.com/lodging/2000000/1620000/1614000/1613977/667d95b8.jpg?impolicy=fcrop&w=357&h=201&p=1&q=medium)

### La Quinta Inn & Suites by Wyndham San Antonio Medical Ctr NW

[](https://www.expedia.ca/San-Antonio-Hotels-La-Quinta-Inn-Suites-By-Wyndham-San-Antonio-Medical-Ctr-NW.h1613977.Hotel-Information)

Medical Center District

8.4/10

Very good

(3,196 reviews)

"Great stay with nice breakfast and clean rooms "

![United States](https://a.travel-assets.com/egds/marks/flags/us.svg)

Leah

CA $122

CA $144 total

includes taxes & fees

Jan 28 - Jan 29

[](https://www.expedia.ca/San-Antonio-Hotels-La-Quinta-Inn-Suites-By-Wyndham-San-Antonio-Medical-Ctr-NW.h1613977.Hotel-Information)

![Lobby](https://images.trvl-media.com/lodging/1000000/30000/20300/20296/e8a306b1.jpg?impolicy=fcrop&w=357&h=201&p=1&q=medium)

![Free daily continental breakfast](https://images.trvl-media.com/lodging/1000000/30000/20300/20296/ba18b5c6.jpg?impolicy=fcrop&w=357&h=201&p=1&q=medium)

![Pillowtop beds, desk, blackout drapes, iron/ironing board](https://images.trvl-media.com/lodging/1000000/30000/20300/20296/6c1ef092.jpg?impolicy=fcrop&w=357&h=201&p=1&q=medium)

![Exterior](https://images.trvl-media.com/lodging/1000000/30000/20300/20296/0c7a5109.jpg?impolicy=fcrop&w=357&h=201&p=1&q=medium)

### La Quinta Inn By Wyndham IH-10 West San Antonio TX

[](https://www.expedia.ca/San-Antonio-Hotels-La-Quinta-Inn-By-Wyndham-San-Antonio-Vance-Jackson.h20296.Hotel-Information)

North Central

6.2/10

(1,002 reviews)

"Area seemed very unsafe"

![United States](https://a.travel-assets.com/egds/marks/flags/us.svg)

Michael

CA $72

CA $85 total

includes taxes & fees

Feb 6 - Feb 7

[](https://www.expedia.ca/San-Antonio-Hotels-La-Quinta-Inn-By-Wyndham-San-Antonio-Vance-Jackson.h20296.Hotel-Information)

Lowest nightly price found within the past 24 hours based on a 1 night stay for 2 adults. Prices and availability subject to change. Additional terms may apply.

[View all properties](https://expedia.ca/Hotel-Search?startDate=2026-02-10&endDate=2026-02-11&regionId=6059170&adults=2&star=50&sort=RECOMMENDED&openPlayBack=true)

## Top Northwest San Antonio Hotel Reviews

![Hyatt Place San Antonio-Northwest/Medical Center](https://images.trvl-media.com/lodging/1000000/50000/41800/41734/8cb01bdd_y.jpg)

### Hyatt Place San Antonio-Northwest/Medical Center

10/10 Excellent

"The facility and the room was very clean. The staff (Abby and Alma) were extremely friendly and helpful. My accommodation was perfect. "

[](https://expedia.ca/San-Antonio-Hotels-Hyatt-Place-San-Antonio-NorthwestMedical-Center.h41734.Hotel-Information)

![Drury Inn & Suites Near La Cantera Parkway](https://images.trvl-media.com/lodging/3000000/2190000/2180400/2180355/aaf7f28d_y.jpg)

### Drury Inn & Suites Near La Cantera Parkway

10/10 Excellent

"Very clean, love the 24 hour gym, pool, hot tub. We'll return. "

[](https://expedia.ca/San-Antonio-Hotels-Drury-Inn-Suites-Near-La-Cantera-Parkway.h2180355.Hotel-Information)

![Best Western Medical Center North Inn & Suites Near Six Flags](https://images.trvl-media.com/lodging/2000000/1350000/1348700/1348602/cafc73cd_y.jpg)

### Best Western Medical Center North Inn & Suites Near Six Flags

10/10 Excellent

"I had an amazing check in experience. The lady helping me was so kind. I was having a day and I really needed that! "

[](https://expedia.ca/San-Antonio-Hotels-Best-Western-Medical-Center-North-Inn-Suites-Near-Six-Flags.h1348602.Hotel-Information)

![La Quinta Inn & Suites by Wyndham San Antonio Medical Ctr NW](https://images.trvl-media.com/lodging/2000000/1620000/1614000/1613977/w9000h6173x0y15-23603cae_y.jpg)

### La Quinta Inn & Suites by Wyndham San Antonio Medical Ctr NW

10/10 Excellent

"Great stay with nice breakfast and clean rooms "

[](https://expedia.ca/San-Antonio-Hotels-La-Quinta-Inn-Suites-By-Wyndham-San-Antonio-Medical-Ctr-NW.h1613977.Hotel-Information)

![The Westin San Antonio North](https://images.trvl-media.com/lodging/1000000/10000/3200/3187/b99867e6_y.jpg)

### The Westin San Antonio North

10/10 Excellent

"Nice rooms"

[](https://expedia.ca/San-Antonio-Hotels-Omni-San-Antonio-Hotel-At-The-Colonnade.h3187.Hotel-Information)

![Spark By Hilton San Antonio Northwest near Six Flags](https://images.trvl-media.com/lodging/1000000/50000/41300/41271/9e3e8920_y.jpg)

### Spark By Hilton San Antonio Northwest near Six Flags

10/10 Excellent

"The room was very specious and clean"

[](https://expedia.ca/San-Antonio-Hotels-Quality-Inn-San-Antonio-Fiesta-At-Six-Flags.h41271.Hotel-Information)

![Bluegreen Vacations Eilan Hotel and Spa, an Ascend Collection Resort](https://images.trvl-media.com/lodging/5000000/4920000/4919800/4919718/08a9974f_y.jpg)

### Bluegreen Vacations Eilan Hotel and Spa, an Ascend Collection Resort

10/10 Excellent

"Very nice room. Great location and restaurants within walking distance. "

[](https://expedia.ca/San-Antonio-Hotels-Eilan-Hotel-And-Spa.h4919718.Hotel-Information)

![Signia by Hilton La Cantera Resort & Spa](https://images.trvl-media.com/lodging/1000000/290000/284400/284306/w3840h2557x0y3-7a64bf70_y.jpg)

### Signia by Hilton La Cantera Resort & Spa

10/10 Excellent

"Staff were fantastically friendly and helpful! The room was clean and the view was great too! "

[](https://expedia.ca/San-Antonio-Hotels-Signia-By-Hilton-La-Cantera-Resort-Spa.h284306.Hotel-Information)

![Holiday Inn Express & Suites San Antonio Medical-Six Flags by IHG](https://images.trvl-media.com/lodging/10000000/9330000/9330000/9329921/a5ac356f_y.jpg)

### Holiday Inn Express & Suites San Antonio Medical-Six Flags by IHG

10/10 Excellent

"They only had one pancake maker and it stopped working the second day I was there. "

[](https://expedia.ca/San-Antonio-Hotels-Holiday-Inn-Express-Suites-San-Antonio-Medical-Six-Flags.h9329921.Hotel-Information)

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- [Flights to Helotes ](https://www.expedia.ca/Cheap-Flights-To-Helotes.d6004945.Travel-Guide-Flights)

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