Title: Book the Best BUSINESS Hotels in Northwest Missouri in 2026 | Expedia.ca [Northwest Missouri Travel Guide](https://expedia.ca/Northwest-Missouri.dx6058810)[Hotels in Northwest Missouri](https://expedia.ca/Northwest-Missouri-Hotels.d6058810.Travel-Guide-Hotels)[Vacation Rentals in Northwest Missouri](https://expedia.ca/Northwest-Missouri-Vacation-Rentals.d6058810.Travel-Guide-VacationRentals)[Flights to Northwest Missouri](https://expedia.ca/Cheap-Flights-To-Northwest-Missouri.d6058810.Travel-Guide-Flights)[Things to do in Northwest Missouri](https://expedia.ca/Things-To-Do-In-Northwest-Missouri.d6058810.Travel-Guide-Activities)[Northwest Missouri Car Rentals](https://expedia.ca/Car-Rentals-In-Northwest-Missouri.d6058810.Car-Rental-Guide)[Northwest Missouri Vacation Packages](https://expedia.ca/Northwest-Missouri.d6058810.Destination-Travel-Guides) ![Vaile Mansion which includes interior views, heritage elements and a house](https://images.trvl-media.com/place/6323538/ff564756-f4f7-413e-8912-b28f6d0d6384.jpg?impolicy=fcrop&w=1200&h=500&q=medium) ![](https://images.trvl-media.com/place/6323538/ff564756-f4f7-413e-8912-b28f6d0d6384.jpg?impolicy=fcrop&w=1200&h=500&q=medium) - ![](https://a.travel-assets.com/travel-assets-manager/pictogram-bex/light__calendar_shield.svg) ### Change your mind Book hotels with free cancellation - ![](https://a.travel-assets.com/travel-assets-manager/pictogram-bex/light__deals.svg) ### Treat yourself Sign in to save 10% or more on thousands of hotels [Sign in](https://www.expedia.ca/login) - ![](https://a.travel-assets.com/travel-assets-manager/pictogram-bex/light__bed.svg) ### Be picky Search almost a million properties worldwide ## Check availability on Northwest Missouri Business Hotels Tonight [Feb 1 - Feb 2](https://www.expedia.ca/Hotel-Search?regionId=6058810&startDate=2026-02-01&endDate=2026-02-02&adults=2&rfrr=TG.LP.CheckPrices.Hotel&openPlayBack=true&travelerType=business_friendly) Tomorrow [Feb 2 - Feb 3](https://www.expedia.ca/Hotel-Search?regionId=6058810&startDate=2026-02-02&endDate=2026-02-03&adults=2&rfrr=TG.LP.CheckPrices.Hotel&openPlayBack=true&travelerType=business_friendly) Next weekend [Feb 6 - Feb 8](https://www.expedia.ca/Hotel-Search?regionId=6058810&startDate=2026-02-06&endDate=2026-02-08&adults=2&rfrr=TG.LP.CheckPrices.Hotel&openPlayBack=true&travelerType=business_friendly) In two weeks [Feb 13 - Feb 15](https://www.expedia.ca/Hotel-Search?regionId=6058810&startDate=2026-02-13&endDate=2026-02-15&adults=2&rfrr=TG.LP.CheckPrices.Hotel&openPlayBack=true&travelerType=business_friendly) ## Our top choices for Northwest Missouri business-friendly hotels ![Lobby](https://images.trvl-media.com/lodging/1000000/10000/4200/4180/d2b9e218.jpg?impolicy=fcrop&w=357&h=201&p=1&q=medium) ![Exterior](https://images.trvl-media.com/lodging/1000000/10000/4200/4180/2dd83c29.jpg?impolicy=fcrop&w=357&h=201&p=1&q=medium) ![Indoor pool](https://images.trvl-media.com/lodging/1000000/10000/4200/4180/ce15b185.jpg?impolicy=fcrop&w=357&h=201&p=1&q=medium) ![Suite, 2 Queen Beds, Accessible, Refrigerator & Microwave (Sofabed, Roll In Shower)](https://images.trvl-media.com/lodging/1000000/10000/4200/4180/97fa97c4.jpg?impolicy=fcrop&w=357&h=201&p=1&q=medium) ### Drury Inn & Suites St Joseph [](https://www.expedia.ca/St-Joseph-Hotels-Drury-Inn-Suites-St-Joseph.h4180.Hotel-Information) St. Joseph 9.4/10 Exceptional (1,002 reviews) "Amazing friendly staff, clean rooms, bathroom was spotless. Enjoyed my stay. " ![United States](https://a.travel-assets.com/egds/marks/flags/us.svg) Aaron CA $136 CA $157 total includes taxes & fees Feb 6 - Feb 7 [](https://www.expedia.ca/St-Joseph-Hotels-Drury-Inn-Suites-St-Joseph.h4180.Hotel-Information) ![Indoor pool, outdoor pool](https://images.trvl-media.com/lodging/2000000/1140000/1140000/1139931/82c1711e.jpg?impolicy=fcrop&w=357&h=201&p=1&q=medium) ![Reception](https://images.trvl-media.com/lodging/2000000/1140000/1140000/1139931/2de574ca.jpg?impolicy=fcrop&w=357&h=201&p=1&q=medium) ![Exterior](https://images.trvl-media.com/lodging/2000000/1140000/1140000/1139931/64e61c4d.jpg?impolicy=fcrop&w=357&h=201&p=1&q=medium) ![Lobby sitting area](https://images.trvl-media.com/lodging/2000000/1140000/1140000/1139931/f4de68bf.jpg?impolicy=fcrop&w=357&h=201&p=1&q=medium) ### Stoney Creek Hotel St. Joseph [](https://www.expedia.ca/St-Joseph-Hotels-Stoney-Creek-Hotel-St-Joseph.h1139931.Hotel-Information) St. Joseph 9.0/10 Wonderful (1,593 reviews) "Clean rooms staff was very friendly and pool was good " ![Canada](https://a.travel-assets.com/egds/marks/flags/ca.svg) Barbara [](https://www.expedia.ca/St-Joseph-Hotels-Stoney-Creek-Hotel-St-Joseph.h1139931.Hotel-Information) ![Interior](https://images.trvl-media.com/lodging/60000000/59770000/59768000/59767971/ca708ae1.jpg?impolicy=fcrop&w=357&h=201&p=1&q=medium) ![In-room safe, desk, blackout drapes, iron/ironing board](https://images.trvl-media.com/lodging/60000000/59770000/59768000/59767971/2f453ae9.jpg?impolicy=fcrop&w=357&h=201&p=1&q=medium) ![Exterior](https://images.trvl-media.com/lodging/60000000/59770000/59768000/59767971/aae281c8.jpg?impolicy=fcrop&w=357&h=201&p=1&q=medium) ![Exterior](https://images.trvl-media.com/lodging/60000000/59770000/59768000/59767971/e1f85005.jpg?impolicy=fcrop&w=357&h=201&p=1&q=medium) ### Holiday Inn Express Oak Grove by IHG [](https://www.expedia.ca/Kansas-City-Hotels-Holiday-Inn-Express-Oak-Grove.h59767971.Hotel-Information) Oak Grove 8.8/10 Excellent (732 reviews) "Clean, quiet, easy check in" ![United States](https://a.travel-assets.com/egds/marks/flags/us.svg) M VIRGINIA CA $129 CA $143 total includes taxes & fees Feb 9 - Feb 10 [](https://www.expedia.ca/Kansas-City-Hotels-Holiday-Inn-Express-Oak-Grove.h59767971.Hotel-Information) ![Single Room, 1 King Bed, Non Smoking](https://images.trvl-media.com/lodging/125000000/124950000/124941900/124941820/b0341cfb.jpg?impolicy=fcrop&w=357&h=201&p=1&q=medium) ![Restaurant](https://images.trvl-media.com/lodging/125000000/124950000/124941900/124941820/102d1522.jpg?impolicy=fcrop&w=357&h=201&p=1&q=medium) ![Premium bedding, desk, laptop workspace, blackout drapes](https://images.trvl-media.com/lodging/125000000/124950000/124941900/124941820/d5747f3c.jpg?impolicy=fcrop&w=357&h=201&p=1&q=medium) ![Exterior detail](https://images.trvl-media.com/lodging/125000000/124950000/124941900/124941820/6a397622.jpg?impolicy=fcrop&w=357&h=201&p=1&q=medium) ### Cambridge Hotel - Kansas City [](https://www.expedia.ca/Kansas-City-Hotels-Cambridge-Hotel-Kansas-City.h124941820.Hotel-Information) Kansas City 8.4/10 Very good (5 reviews) "Just a quick one night stay, great breakfast provided and friendly staff. " ![United States](https://a.travel-assets.com/egds/marks/flags/us.svg) Kevin CA $109 CA $131 total includes taxes & fees Feb 3 - Feb 4 [](https://www.expedia.ca/Kansas-City-Hotels-Cambridge-Hotel-Kansas-City.h124941820.Hotel-Information) ![Studio Suite, Multiple Beds, Non Smoking](https://images.trvl-media.com/lodging/2000000/1620000/1615600/1615553/0f5cb1e2.jpg?impolicy=fcrop&w=357&h=201&p=1&q=medium) ![Fitness facility](https://images.trvl-media.com/lodging/2000000/1620000/1615600/1615553/e933c15f.jpg?impolicy=fcrop&w=357&h=201&p=1&q=medium) ![Business centre](https://images.trvl-media.com/lodging/2000000/1620000/1615600/1615553/7c73d715.jpg?impolicy=fcrop&w=357&h=201&p=1&q=medium) ![Front of property](https://images.trvl-media.com/lodging/2000000/1620000/1615600/1615553/27ccb3b9.jpg?impolicy=fcrop&w=357&h=201&p=1&q=medium) ### Cobblestone Inn & Suites - Trenton [](https://www.expedia.ca/Chillicothe-Hotels-Cobblestone-Inn-Suites-Trenton.h1615553.Hotel-Information) Trenton 9.0/10 Wonderful (308 reviews) "Excellent stay" ![United States](https://a.travel-assets.com/egds/marks/flags/us.svg) Wilber [](https://www.expedia.ca/Chillicothe-Hotels-Cobblestone-Inn-Suites-Trenton.h1615553.Hotel-Information) ![Suite, 2 Queen Beds, Non Smoking](https://images.trvl-media.com/lodging/1000000/530000/523200/523135/2f4fa792.jpg?impolicy=fcrop&w=357&h=201&p=1&q=medium) ![Property entrance](https://images.trvl-media.com/lodging/1000000/530000/523200/523135/e7957ce0.jpg?impolicy=fcrop&w=357&h=201&p=1&q=medium) ![Property entrance](https://images.trvl-media.com/lodging/1000000/530000/523200/523135/b47b1cf7.jpg?impolicy=fcrop&w=357&h=201&p=1&q=medium) ![Suite, 1 King Bed, Non Smoking](https://images.trvl-media.com/lodging/1000000/530000/523200/523135/d506e333.jpg?impolicy=fcrop&w=357&h=201&p=1&q=medium) ### Americas Best Value Inn & Suites Maryville [](https://www.expedia.ca/St-Joseph-Hotels-Americas-Best-Value-Inn-Suites-Maryville.h523135.Hotel-Information) Maryville 8.2/10 Very good (800 reviews) "Clean room. Good variety with breakfast." ![United States](https://a.travel-assets.com/egds/marks/flags/us.svg) Laura CA $101 CA $115 total includes taxes & fees Feb 3 - Feb 4 [](https://www.expedia.ca/St-Joseph-Hotels-Americas-Best-Value-Inn-Suites-Maryville.h523135.Hotel-Information) ![Lobby](https://images.trvl-media.com/lodging/19000000/18180000/18179000/18178902/b42a1684.jpg?impolicy=fcrop&w=357&h=201&p=1&q=medium) ![Indoor pool](https://images.trvl-media.com/lodging/19000000/18180000/18179000/18178902/e0d9868d.jpg?impolicy=fcrop&w=357&h=201&p=1&q=medium) ![Exterior](https://images.trvl-media.com/lodging/19000000/18180000/18179000/18178902/7977062c.jpg?impolicy=fcrop&w=357&h=201&p=1&q=medium) ![Property amenity](https://images.trvl-media.com/lodging/19000000/18180000/18179000/18178902/2dbfeb6b.jpg?impolicy=fcrop&w=357&h=201&p=1&q=medium) ### Fairfield Inn & Suites by Marriott St. Joseph [](https://www.expedia.ca/St-Joseph-Hotels-Fairfield-Inn-Suites-By-Marriott-St-Joseph.h18178902.Hotel-Information) St. Joseph 9.6/10 Exceptional (476 reviews) "Clean room and friendly staff. " ![United States](https://a.travel-assets.com/egds/marks/flags/us.svg) Jerome CA $143 CA $167 total includes taxes & fees Feb 8 - Feb 9 [](https://www.expedia.ca/St-Joseph-Hotels-Fairfield-Inn-Suites-By-Marriott-St-Joseph.h18178902.Hotel-Information) ![Desk, blackout drapes, iron/ironing board, rollaway beds](https://images.trvl-media.com/lodging/1000000/900000/897900/897802/543e293f.jpg?impolicy=fcrop&w=357&h=201&p=1&q=medium) ![Standard Room, 1 King Bed](https://images.trvl-media.com/lodging/1000000/900000/897900/897802/ad36d5e6.jpg?impolicy=fcrop&w=357&h=201&p=1&q=medium) ![Courtyard](https://images.trvl-media.com/lodging/1000000/900000/897900/897802/7d6ed87e.jpg?impolicy=fcrop&w=357&h=201&p=1&q=medium) ![Exterior](https://images.trvl-media.com/lodging/1000000/900000/897900/897802/52bc71b3.jpg?impolicy=fcrop&w=357&h=201&p=1&q=medium) ### Super 8 by Wyndham Bethany MO [](https://www.expedia.ca/St-Joseph-Hotels-Super-8-By-Wyndham-Bethany-MO.h897802.Hotel-Information) Bethany 8.0/10 Very good (1,000 reviews) "All was wonderful. Great place." ![United States](https://a.travel-assets.com/egds/marks/flags/us.svg) Gerald CA $104 CA $112 total includes taxes & fees Feb 26 - Feb 27 [](https://www.expedia.ca/St-Joseph-Hotels-Super-8-By-Wyndham-Bethany-MO.h897802.Hotel-Information) ![Fridge, microwave, stovetop, coffee/tea maker](https://images.trvl-media.com/lodging/110000000/109470000/109463300/109463264/aa4717a0.jpg?impolicy=fcrop&w=357&h=201&p=1&q=medium) ![Premium bedding, pillowtop beds, desk, laptop workspace](https://images.trvl-media.com/lodging/110000000/109470000/109463300/109463264/29a35617.jpg?impolicy=fcrop&w=357&h=201&p=1&q=medium) ![Lobby sitting area](https://images.trvl-media.com/lodging/110000000/109470000/109463300/109463264/da4c15cf.jpg?impolicy=fcrop&w=357&h=201&p=1&q=medium) ![Fridge, microwave, stovetop, coffee/tea maker](https://images.trvl-media.com/lodging/110000000/109470000/109463300/109463264/w3000h1897x0y3-644920c5.jpg?impolicy=fcrop&w=357&h=201&p=1&q=medium) ### My Place Hotel St Joseph MO [](https://www.expedia.ca/St-Joseph-Hotels-My-Place-Hotel-St-Joesph-MO.h109463264.Hotel-Information) St. Joseph 9.2/10 Wonderful (215 reviews) "It was a clean place to stay." ![United States](https://a.travel-assets.com/egds/marks/flags/us.svg) Ayden CA $116 CA $135 total includes taxes & fees Feb 8 - Feb 9 [](https://www.expedia.ca/St-Joseph-Hotels-My-Place-Hotel-St-Joesph-MO.h109463264.Hotel-Information) ![Indoor pool, open 7 AM to midnight, sun loungers](https://images.trvl-media.com/lodging/1000000/330000/328600/328594/23684e7b.jpg?impolicy=fcrop&w=357&h=201&p=1&q=medium) ![Business Room, 1 King Bed, Non Smoking (One-Bedroom) | Living area](https://images.trvl-media.com/lodging/1000000/330000/328600/328594/b836f848.jpg?impolicy=fcrop&w=357&h=201&p=1&q=medium) ![Suite, 1 King Bed, Non Smoking (One-Bedroom) | Living area](https://images.trvl-media.com/lodging/1000000/330000/328600/328594/94e71b28.jpg?impolicy=fcrop&w=357&h=201&p=1&q=medium) ![Studio Suite, 2 Queen Beds, Non Smoking](https://images.trvl-media.com/lodging/1000000/330000/328600/328594/645d3074.jpg?impolicy=fcrop&w=357&h=201&p=1&q=medium) ### Ramada by Wyndham Platte City KCI Airport [](https://www.expedia.ca/Kansas-City-Hotels-Ramada-By-Wyndham-Platte-City-KCI-Airport.h328594.Hotel-Information) Platte City 8.0/10 Very good (1,048 reviews) "Room was clean, staff was helpful! " ![United States](https://a.travel-assets.com/egds/marks/flags/us.svg) Baili CA $109 CA $123 total includes taxes & fees Feb 3 - Feb 4 [](https://www.expedia.ca/Kansas-City-Hotels-Ramada-By-Wyndham-Platte-City-KCI-Airport.h328594.Hotel-Information) Lowest nightly price found within the past 24 hours based on a 1 night stay for 2 adults. Prices and availability subject to change. Additional terms may apply. [View all properties](https://expedia.ca/Hotel-Search?startDate=2026-02-16&endDate=2026-02-17®ionId=6058810&adults=2&travelerType=business_friendly&sort=RECOMMENDED&openPlayBack=true) ## Top Northwest Missouri Hotel Reviews ![Crowne Plaza Kansas City Downtown by IHG](https://images.trvl-media.com/lodging/1000000/90000/85200/85141/f05c83dd_y.jpg) ### Crowne Plaza Kansas City Downtown by IHG 10/10 Excellent "Clean room and nice on site amenities!" [](https://expedia.ca/Kansas-City-Hotels-Crowne-Plaza-Kansas-City-Downtown.h85141.Hotel-Information) ![Sonesta Select Kansas City South Overland Park](https://images.trvl-media.com/lodging/1000000/30000/24200/24177/eff785b1_y.jpg) ### Sonesta Select Kansas City South Overland Park 10/10 Excellent "Room was clean, well stocked, and nice lighting. My only dissatisfaction was the bed was so high, I had to use a chair to get into it. I am very short at 4’9” but still? The halls were very cold. Housekeeping staff super nice! Thank you Martha and Mariah. " [](https://expedia.ca/Kansas-City-Hotels-Sonesta-Select-Kansas-City-South-Overland-Park.h24177.Hotel-Information) ![Orangewood Inn & Suites Kansas City Airport](https://images.trvl-media.com/lodging/1000000/10000/8600/8523/f51a002b_y.jpg) ### Orangewood Inn & Suites Kansas City Airport 10/10 Excellent "El cuarto muy cómodo y el staff es muy amable!" [](https://expedia.ca/Kansas-City-Hotels-Orangewood-Inn-Suites-Kansas-City-Airport.h8523.Hotel-Information) ![Ameristar Casino Hotel Kansas City](https://images.trvl-media.com/lodging/1000000/50000/41600/41546/ad53926e_y.jpg) ### Ameristar Casino Hotel Kansas City 10/10 Excellent "All" [](https://expedia.ca/Kansas-City-Hotels-Ameristar-Casino-Hotel-Kansas-City.h41546.Hotel-Information) ![Kansas City Marriott Downtown](https://images.trvl-media.com/lodging/1000000/30000/22300/22215/a735d9ee_y.jpg) ### Kansas City Marriott Downtown 10/10 Excellent "The staff was fantastic " [](https://expedia.ca/Kansas-City-Hotels-Kansas-City-Marriott-Downtown.h22215.Hotel-Information) ![Four Points by Sheraton Kansas City Airport](https://images.trvl-media.com/lodging/1000000/20000/19700/19602/74b7dd37_y.jpg) ### Four Points by Sheraton Kansas City Airport 10/10 Excellent "It is close to the airport and is a peaceful, quiet place to stay. The restaurant on site offers a variety of good food including a breakfast buffet." [](https://expedia.ca/Kansas-City-Hotels-Four-Points-By-Sheraton-Kansas-City-Airport.h19602.Hotel-Information) ![Stoney Creek Hotel Kansas City - Independence](https://images.trvl-media.com/lodging/10000000/9730000/9724700/9724606/261f0ada_y.jpg) ### Stoney Creek Hotel Kansas City - Independence 10/10 Excellent "Awesome staff room was very clean - had free drinks in the bar and they were fantastic --i will go back" [](https://expedia.ca/Kansas-City-Hotels-Stoney-Creek-Hotel-Kansas-City-Independence.h9724606.Hotel-Information) ![Argosy Casino & Hotel](https://images.trvl-media.com/lodging/2000000/1650000/1640200/1640113/0238e32c_y.jpg) ### Argosy Casino & Hotel 10/10 Excellent "The staff was very friendly & helpful. The room was neat & clean. Excellent restaurants on site." [](https://expedia.ca/Kansas-City-Hotels-Argosy-Casino-Hotel-And-Spa.h1640113.Hotel-Information) ![Harrah's Kansas City Hotel and Casino - A Caesars Rewards Destination](https://images.trvl-media.com/lodging/2000000/1190000/1180500/1180485/32e806fc_y.jpg) ### Harrah's Kansas City Hotel and Casino - A Caesars Rewards Destination 10/10 Excellent "Easy check-in, nice rooms." [](https://expedia.ca/Kansas-City-Hotels-Harrahs-Kansas-City-Hotel-And-Casino.h1180485.Hotel-Information) ## Frequently asked questions ### How much do business-friendly hotels in Northwest Missouri cost? ### What are the best business-friendly hotels in Northwest Missouri? ### How many business-friendly hotels are there in Northwest Missouri? ### What are the best cheap business-friendly hotels in Northwest Missouri? ### Are there any family-friendly hotels in Northwest Missouri that are also business friendly? ### Are there any 5-star business-friendly hotels in Northwest Missouri? ### Why book your business-friendly hotel in Northwest Missouri with Expedia? ### How can I find cheap business-friendly hotels in Northwest Missouri? ### What is there to do in Northwest Missouri near my business-friendly hotel? ## Explore a world of travel with Expedia - Lodging - Flights - Packages - Cars - More ways to book - [4 Star Hotels in Holt ](https://www.expedia.ca/4Star-Holt-Hotels.s40-0-d553248634983503554.Travel-Guide-Filter-Hotels) - 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