Title: Book the Best BUSINESS Hotels in Northwest Missouri in 2026 | Expedia.ca [Northwest Missouri Travel Guide](https://expedia.ca/Northwest-Missouri.dx6058810)[Hotels in Northwest Missouri](https://expedia.ca/Northwest-Missouri-Hotels.d6058810.Travel-Guide-Hotels)[Vacation Rentals in Northwest Missouri](https://expedia.ca/Northwest-Missouri-Vacation-Rentals.d6058810.Travel-Guide-VacationRentals)[Flights to Northwest Missouri](https://expedia.ca/Cheap-Flights-To-Northwest-Missouri.d6058810.Travel-Guide-Flights)[Things to do in Northwest Missouri](https://expedia.ca/Things-To-Do-In-Northwest-Missouri.d6058810.Travel-Guide-Activities)[Northwest Missouri Car Rentals](https://expedia.ca/Car-Rentals-In-Northwest-Missouri.d6058810.Car-Rental-Guide)[Northwest Missouri Vacation Packages](https://expedia.ca/Northwest-Missouri.d6058810.Destination-Travel-Guides) ![Science City at Union Station which includes signage, a city and a garden](https://images.trvl-media.com/place/6323295/ad08a046-bfa6-4ace-a140-36f5cf75496b.jpg?impolicy=fcrop&w=1200&h=500&q=medium) # Find Business Hotels in Northwest Missouri, MO from CA $111 - ![](https://a.travel-assets.com/travel-assets-manager/pictogram-bex/light__calendar_shield.svg) ### Change your mind Book hotels with free cancellation - ![](https://a.travel-assets.com/travel-assets-manager/pictogram-bex/light__deals.svg) ### Treat yourself Sign in to save 10% or more on thousands of hotels [Sign in](https://www.expedia.ca/login) - ![](https://a.travel-assets.com/travel-assets-manager/pictogram-bex/light__bed.svg) ### Be picky Search almost a million properties worldwide ## Check availability on Northwest Missouri Business Hotels Tonight [Dec 18 - Dec 19](https://www.expedia.ca/Hotel-Search?regionId=6058810&startDate=2025-12-18&endDate=2025-12-19&adults=2&rfrr=TG.LP.CheckPrices.Hotel&openPlayBack=true&travelerType=business_friendly) Tomorrow [Dec 19 - Dec 20](https://www.expedia.ca/Hotel-Search?regionId=6058810&startDate=2025-12-19&endDate=2025-12-20&adults=2&rfrr=TG.LP.CheckPrices.Hotel&openPlayBack=true&travelerType=business_friendly) This weekend [Dec 19 - Dec 21](https://www.expedia.ca/Hotel-Search?regionId=6058810&startDate=2025-12-19&endDate=2025-12-21&adults=2&rfrr=TG.LP.CheckPrices.Hotel&openPlayBack=true&travelerType=business_friendly) Next weekend [Dec 26 - Dec 28](https://www.expedia.ca/Hotel-Search?regionId=6058810&startDate=2025-12-26&endDate=2025-12-28&adults=2&rfrr=TG.LP.CheckPrices.Hotel&openPlayBack=true&travelerType=business_friendly) ## Our top choices for Northwest Missouri business-friendly hotels ![Lobby](https://images.trvl-media.com/lodging/1000000/10000/4200/4180/d2b9e218.jpg?impolicy=fcrop&w=357&h=201&p=1&q=medium) ![Exterior](https://images.trvl-media.com/lodging/1000000/10000/4200/4180/2dd83c29.jpg?impolicy=fcrop&w=357&h=201&p=1&q=medium) ![Indoor pool](https://images.trvl-media.com/lodging/1000000/10000/4200/4180/ce15b185.jpg?impolicy=fcrop&w=357&h=201&p=1&q=medium) ![Suite, 2 Queen Beds, Accessible, Refrigerator & Microwave (Sofabed, Roll In Shower)](https://images.trvl-media.com/lodging/1000000/10000/4200/4180/97fa97c4.jpg?impolicy=fcrop&w=357&h=201&p=1&q=medium) ### Drury Inn & Suites St Joseph [](https://www.expedia.ca/St-Joseph-Hotels-Drury-Inn-Suites-St-Joseph.h4180.Hotel-Information) St. Joseph 9.2/10 Wonderful (1001) "Great place to stay in St. Joseph. Always a clean room, good breakfast and friendly staff." ![United States](https://a.travel-assets.com/egds/marks/flags/us.svg) melissa CA $138 CA $159 total includes taxes & fees Dec 27 - Dec 28 [](https://www.expedia.ca/St-Joseph-Hotels-Drury-Inn-Suites-St-Joseph.h4180.Hotel-Information) ![Free daily buffet breakfast](https://images.trvl-media.com/lodging/7000000/6850000/6846800/6846757/47ec36cb.jpg?impolicy=fcrop&w=357&h=201&p=1&q=medium) ![Exterior](https://images.trvl-media.com/lodging/7000000/6850000/6846800/6846757/d40daa76.jpg?impolicy=fcrop&w=357&h=201&p=1&q=medium) ![Desk, laptop workspace, iron/ironing board, free WiFi](https://images.trvl-media.com/lodging/7000000/6850000/6846800/6846757/8955ad72.jpg?impolicy=fcrop&w=357&h=201&p=1&q=medium) ![Exterior](https://images.trvl-media.com/lodging/7000000/6850000/6846800/6846757/55bf67a3.jpg?impolicy=fcrop&w=357&h=201&p=1&q=medium) ### Holiday Inn Express Hotel & Suites St. Joseph by IHG [](https://www.expedia.ca/St-Joseph-Hotels-Holiday-Inn-Express-Hotel-Suites-St-Joseph.h6846757.Hotel-Information) St. Joseph 9.2/10 Wonderful (787) "We had a wonderful stay. Rooms were very clean and spacious. Staff accommodating and professional. Breakfast very good!" ![United States](https://a.travel-assets.com/egds/marks/flags/us.svg) Regina CA $133 CA $154 total includes taxes & fees Dec 27 - Dec 28 [](https://www.expedia.ca/St-Joseph-Hotels-Holiday-Inn-Express-Hotel-Suites-St-Joseph.h6846757.Hotel-Information) ![Pool](https://images.trvl-media.com/lodging/1000000/50000/42200/42192/85cb1016.jpg?impolicy=fcrop&w=357&h=201&p=1&q=medium) ![Standard Room, 1 King Bed, Non Smoking](https://images.trvl-media.com/lodging/1000000/50000/42200/42192/28b1385b.jpg?impolicy=fcrop&w=357&h=201&p=1&q=medium) ![Lobby](https://images.trvl-media.com/lodging/1000000/50000/42200/42192/a59c6aa9.jpg?impolicy=fcrop&w=357&h=201&p=1&q=medium) ![In-room safe, desk, blackout drapes, iron/ironing board](https://images.trvl-media.com/lodging/1000000/50000/42200/42192/27251199.jpg?impolicy=fcrop&w=357&h=201&p=1&q=medium) ### Quality Inn Cameron [](https://www.expedia.ca/St-Joseph-Hotels-Quality-Inn-Cameron.h42192.Hotel-Information) Cameron 8.4/10 Very good (623) "Nice place for price. Convenient location." ![United States](https://a.travel-assets.com/egds/marks/flags/us.svg) Dan CA $127 CA $140 total includes taxes & fees Jan 18 - Jan 19, 2026 [](https://www.expedia.ca/St-Joseph-Hotels-Quality-Inn-Cameron.h42192.Hotel-Information) ![Fridge, microwave, stovetop, coffee/tea maker](https://images.trvl-media.com/lodging/110000000/109470000/109463300/109463264/aa4717a0.jpg?impolicy=fcrop&w=357&h=201&p=1&q=medium) ![Lobby sitting area](https://images.trvl-media.com/lodging/110000000/109470000/109463300/109463264/da4c15cf.jpg?impolicy=fcrop&w=357&h=201&p=1&q=medium) ![Fridge, microwave, stovetop, coffee/tea maker](https://images.trvl-media.com/lodging/110000000/109470000/109463300/109463264/w3000h1897x0y3-644920c5.jpg?impolicy=fcrop&w=357&h=201&p=1&q=medium) ![Premium bedding, pillowtop beds, desk, laptop workspace](https://images.trvl-media.com/lodging/110000000/109470000/109463300/109463264/29a35617.jpg?impolicy=fcrop&w=357&h=201&p=1&q=medium) ### My Place Hotel St Joseph MO [](https://www.expedia.ca/St-Joseph-Hotels-My-Place-Hotel-St-Joesph-MO.h109463264.Hotel-Information) St. Joseph 9.2/10 Wonderful (203) "Excellent facility and clean rooms." ![United States](https://a.travel-assets.com/egds/marks/flags/us.svg) Javier CA $110 CA $127 total includes taxes & fees Jan 18 - Jan 19, 2026 [](https://www.expedia.ca/St-Joseph-Hotels-My-Place-Hotel-St-Joesph-MO.h109463264.Hotel-Information) ![Exterior](https://images.trvl-media.com/lodging/79000000/78410000/78404800/78404731/a9a6148e.jpg?impolicy=fcrop&w=357&h=201&p=1&q=medium) ![Room, 2 Queen Beds, Refrigerator](https://images.trvl-media.com/lodging/79000000/78410000/78404800/78404731/6b86d2b6.jpg?impolicy=fcrop&w=357&h=201&p=1&q=medium) ![Terrace/patio](https://images.trvl-media.com/lodging/79000000/78410000/78404800/78404731/ef0c89ec.jpg?impolicy=fcrop&w=357&h=201&p=1&q=medium) ![Free daily buffet breakfast](https://images.trvl-media.com/lodging/79000000/78410000/78404800/78404731/52e8a1f4.jpg?impolicy=fcrop&w=357&h=201&p=1&q=medium) ### Hampton Inn Kansas City Southeast, Mo [](https://www.expedia.ca/Kansas-City-Hotels-Hampton-Inn-Kansas-City-Southeast.h78404731.Hotel-Information) South Kansas City 9.2/10 Wonderful (389) "good staff, breakfast, nice facilities, clean." ![United States](https://a.travel-assets.com/egds/marks/flags/us.svg) GURPREET CA $136 CA $163 total includes taxes & fees Jan 7 - Jan 8, 2026 [](https://www.expedia.ca/Kansas-City-Hotels-Hampton-Inn-Kansas-City-Southeast.h78404731.Hotel-Information) ![Desk, blackout drapes, iron/ironing board, rollaway beds](https://images.trvl-media.com/lodging/1000000/900000/897900/897802/543e293f.jpg?impolicy=fcrop&w=357&h=201&p=1&q=medium) ![Indoor pool](https://images.trvl-media.com/lodging/1000000/900000/897900/897802/8b9457bf.jpg?impolicy=fcrop&w=357&h=201&p=1&q=medium) ![Standard Room, 1 King Bed](https://images.trvl-media.com/lodging/1000000/900000/897900/897802/ad36d5e6.jpg?impolicy=fcrop&w=357&h=201&p=1&q=medium) ![Exterior](https://images.trvl-media.com/lodging/1000000/900000/897900/897802/52bc71b3.jpg?impolicy=fcrop&w=357&h=201&p=1&q=medium) ### Super 8 by Wyndham Bethany MO [](https://www.expedia.ca/St-Joseph-Hotels-Super-8-By-Wyndham-Bethany-MO.h897802.Hotel-Information) Bethany 8.0/10 Very good (1006) "The room was very clean and the facility was perfect for an overnight stay." ![United States](https://a.travel-assets.com/egds/marks/flags/us.svg) Kyla CA $108 CA $116 total includes taxes & fees Jan 12 - Jan 13, 2026 [](https://www.expedia.ca/St-Joseph-Hotels-Super-8-By-Wyndham-Bethany-MO.h897802.Hotel-Information) ![Indoor pool, outdoor pool](https://images.trvl-media.com/lodging/2000000/1140000/1140000/1139931/82c1711e.jpg?impolicy=fcrop&w=357&h=201&p=1&q=medium) ![Superior Single Room, 1 King Bed with Sofa bed, Hot Tub](https://images.trvl-media.com/lodging/2000000/1140000/1140000/1139931/a2c57571.jpg?impolicy=fcrop&w=357&h=201&p=1&q=medium) ![Exterior](https://images.trvl-media.com/lodging/2000000/1140000/1140000/1139931/64e61c4d.jpg?impolicy=fcrop&w=357&h=201&p=1&q=medium) ![Lobby sitting area](https://images.trvl-media.com/lodging/2000000/1140000/1140000/1139931/f4de68bf.jpg?impolicy=fcrop&w=357&h=201&p=1&q=medium) ### Stoney Creek Hotel St. Joseph [](https://www.expedia.ca/St-Joseph-Hotels-Stoney-Creek-Hotel-St-Joseph.h1139931.Hotel-Information) St. Joseph 9.0/10 Wonderful (1558) "Wonderful place will definitely stay here again " ![United States](https://a.travel-assets.com/egds/marks/flags/us.svg) Jessica [](https://www.expedia.ca/St-Joseph-Hotels-Stoney-Creek-Hotel-St-Joseph.h1139931.Hotel-Information) ![Indoor pool, open 7 AM to midnight, sun loungers](https://images.trvl-media.com/lodging/1000000/330000/328600/328594/23684e7b.jpg?impolicy=fcrop&w=357&h=201&p=1&q=medium) ![Business Room, 1 King Bed, Non Smoking (One-Bedroom) | Living area](https://images.trvl-media.com/lodging/1000000/330000/328600/328594/b836f848.jpg?impolicy=fcrop&w=357&h=201&p=1&q=medium) ![Lobby sitting area](https://images.trvl-media.com/lodging/1000000/330000/328600/328594/5b2cb9b9.jpg?impolicy=fcrop&w=357&h=201&p=1&q=medium) ![Studio Suite, 2 Queen Beds, Non Smoking](https://images.trvl-media.com/lodging/1000000/330000/328600/328594/645d3074.jpg?impolicy=fcrop&w=357&h=201&p=1&q=medium) ### Ramada by Wyndham Platte City KCI Airport [](https://www.expedia.ca/Kansas-City-Hotels-Ramada-By-Wyndham-Platte-City-KCI-Airport.h328594.Hotel-Information) Platte City 8.0/10 Very good (1011) "Great place to stay just stopping thru the area. Friendly staff, very clean. Breakfast is limited, but as expected. Great place to grab a quick breakfast next door." ![United States](https://a.travel-assets.com/egds/marks/flags/us.svg) Melissa CA $98 CA $111 total includes taxes & fees Jan 4 - Jan 5, 2026 [](https://www.expedia.ca/Kansas-City-Hotels-Ramada-By-Wyndham-Platte-City-KCI-Airport.h328594.Hotel-Information) ![Lobby](https://images.trvl-media.com/lodging/3000000/2400000/2393000/2392999/506d5e79.jpg?impolicy=fcrop&w=357&h=201&p=1&q=medium) ![Free daily on-the-go breakfast](https://images.trvl-media.com/lodging/3000000/2400000/2393000/2392999/e24e2611.jpg?impolicy=fcrop&w=357&h=201&p=1&q=medium) ![Exterior](https://images.trvl-media.com/lodging/3000000/2400000/2393000/2392999/80f0a03d.jpg?impolicy=fcrop&w=357&h=201&p=1&q=medium) ![Room, 2 Queen Beds, Non Smoking](https://images.trvl-media.com/lodging/3000000/2400000/2393000/2392999/e83282fc.jpg?impolicy=fcrop&w=357&h=201&p=1&q=medium) ### La Quinta Inn & Suites by Wyndham Blue Springs [](https://www.expedia.ca/Kansas-City-Hotels-La-Quinta-Inn-Suites-By-Wyndham-Blue-Springs.h2392999.Hotel-Information) Blue Springs 8.4/10 Very good (1000) "Perfect location " ![United States](https://a.travel-assets.com/egds/marks/flags/us.svg) Jessica CA $102 CA $118 total includes taxes & fees Jan 2 - Jan 3, 2026 [](https://www.expedia.ca/Kansas-City-Hotels-La-Quinta-Inn-Suites-By-Wyndham-Blue-Springs.h2392999.Hotel-Information) ![Snack bar](https://images.trvl-media.com/lodging/1000000/220000/215300/215262/182fad92.jpg?impolicy=fcrop&w=357&h=201&p=1&q=medium) ![Exterior](https://images.trvl-media.com/lodging/1000000/220000/215300/215262/w3836h2556x4y4-071ab96c.jpg?impolicy=fcrop&w=357&h=201&p=1&q=medium) ![Indoor pool, sun loungers](https://images.trvl-media.com/lodging/1000000/220000/215300/215262/f6416a89.jpg?impolicy=fcrop&w=357&h=201&p=1&q=medium) ![Two queen beds non smoking](https://images.trvl-media.com/lodging/1000000/220000/215300/215262/74ecd2c0.jpg?impolicy=fcrop&w=357&h=201&p=1&q=medium) ### Hampton Inn Kansas City - Liberty [](https://www.expedia.ca/Kansas-City-Hotels-Hampton-Inn-Kansas-City-Liberty.h215262.Hotel-Information) Shoal Creek 9.4/10 Exceptional (1000) "Nice for our weekend stay." ![United States](https://a.travel-assets.com/egds/marks/flags/us.svg) Cassidy CA $135 CA $161 total includes taxes & fees Dec 26 - Dec 27 [](https://www.expedia.ca/Kansas-City-Hotels-Hampton-Inn-Kansas-City-Liberty.h215262.Hotel-Information) Lowest nightly price found within the past 24 hours based on a 1 night stay for 2 adults. Prices and availability subject to change. Additional terms may apply. [View all properties](https://expedia.ca/Hotel-Search?startDate=2026-01-01&endDate=2026-01-02®ionId=6058810&adults=2&travelerType=business_friendly&sort=RECOMMENDED&openPlayBack=true) ## Top Northwest Missouri Hotel Reviews ![Four Points by Sheraton Kansas City Airport](https://images.trvl-media.com/lodging/1000000/20000/19700/19602/74b7dd37_y.jpg) ### Four Points by Sheraton Kansas City Airport 10/10 Excellent "I stay there often. It’s always exemplary " [](https://expedia.ca/Kansas-City-Hotels-Four-Points-By-Sheraton-Kansas-City-Airport.h19602.Hotel-Information) ![Hotel Lotus Kansas City Merriam](https://images.trvl-media.com/lodging/1000000/50000/42600/42529/5f6612f3_y.jpg) ### Hotel Lotus Kansas City Merriam 10/10 Excellent "I enjoyed the breakfast. " [](https://expedia.ca/Mission-Hotels-Hotel-Lotus-Kansas-City-Merriam.h42529.Hotel-Information) ![Hotel Lotus Kansas City Stadium](https://images.trvl-media.com/lodging/1000000/50000/40100/40014/33318c7a_y.jpg) ### Hotel Lotus Kansas City Stadium 10/10 Excellent "Clean room and friendly staff" [](https://expedia.ca/Kansas-City-Hotels-Hotel-Lotus.h40014.Hotel-Information) ![Stoney Creek Hotel Kansas City - Independence](https://images.trvl-media.com/lodging/10000000/9730000/9724700/9724606/261f0ada_y.jpg) ### Stoney Creek Hotel Kansas City - Independence 10/10 Excellent "We had a nice comfortable stay. " [](https://expedia.ca/Kansas-City-Hotels-Stoney-Creek-Hotel-Kansas-City-Independence.h9724606.Hotel-Information) ![Kansas City Marriott Downtown](https://images.trvl-media.com/lodging/1000000/30000/22300/22215/a735d9ee_y.jpg) ### Kansas City Marriott Downtown 10/10 Excellent "Everything was great. " [](https://expedia.ca/Kansas-City-Hotels-Kansas-City-Marriott-Downtown.h22215.Hotel-Information) ![Argosy Casino & Hotel](https://images.trvl-media.com/lodging/2000000/1650000/1640200/1640113/0238e32c_y.jpg) ### Argosy Casino & Hotel 10/10 Excellent "Nice place" [](https://expedia.ca/Kansas-City-Hotels-Argosy-Casino-Hotel-And-Spa.h1640113.Hotel-Information) ![Orangewood Inn & Suites Kansas City Airport](https://images.trvl-media.com/lodging/1000000/10000/8600/8523/f51a002b_y.jpg) ### Orangewood Inn & Suites Kansas City Airport 10/10 Excellent "Staff was helpful and location was good. The hotel had lots of amenities and breakfast. Overall, great experience, nice, clean room. " [](https://expedia.ca/Kansas-City-Hotels-Orangewood-Inn-Suites-Kansas-City-Airport.h8523.Hotel-Information) ![Seville Plaza Streetcar Hotel Museum District, Trademark](https://images.trvl-media.com/lodging/1000000/20000/10400/10318/cb67c9ed_y.jpg) ### Seville Plaza Streetcar Hotel Museum District, Trademark 10/10 Excellent "The facility is clean and the service is wonderful. Our room had a double whirlpool tub that we enjoyed very much! We werent expecting it but it was just wonderful. The hotel is close to so many KC venues. The area is at the edge of downtown so its a mix of retail, industry, corporate, and some street people. But nothing unexpected in a downtown area. The small parking lot is enclosed but we saw no reason to be concerned. We felt safe and just truly enjoyed the people we met who work there. " [](https://expedia.ca/Kansas-City-Hotels-Best-Western-Plus-Seville-Plaza-Hotel.h10318.Hotel-Information) ![American Inn North Kansas City](https://images.trvl-media.com/lodging/9000000/8340000/8332000/8331961/3c58d2c0_y.jpg) ### American Inn North Kansas City 10/10 Excellent "It was my first stay here. The room was quite large and comfortable as was the bed. Enjoying my night there." [](https://expedia.ca/Kansas-City-Hotels-American-Inn-North-Kansas-City.h8331961.Hotel-Information) ## Frequently asked questions ### How much do business-friendly hotels in Northwest Missouri cost? ### What are the best business-friendly hotels in Northwest Missouri? ### How many business-friendly hotels are there in Northwest Missouri? ### What are the best cheap business-friendly hotels in Northwest Missouri? ### Are there any family-friendly hotels in Northwest Missouri that are also business friendly? ### Are there any 5-star business-friendly hotels in Northwest Missouri? ### Why book your business-friendly hotel in Northwest Missouri with Expedia? ### How can I find cheap business-friendly hotels in Northwest Missouri? ### What is there to do in Northwest Missouri near my business-friendly hotel? ## Explore a world of travel with Expedia - Lodging - Flights - Packages - Cars - More ways to book - [4 Star Hotels in Holt ](https://www.expedia.ca/4Star-Holt-Hotels.s40-0-d553248634983503554.Travel-Guide-Filter-Hotels) - 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