Title: Book the Best Northwest Alabama LUXURY Hotels - Upscale Hotels in Northwest Alabama, AL | Expedia.ca [Northwest Alabama Travel Guide](https://expedia.ca/Northwest-Alabama.dx6057725)[Hotels in Northwest Alabama](https://expedia.ca/Northwest-Alabama-Hotels.d6057725.Travel-Guide-Hotels)[Vacation Rentals in Northwest Alabama](https://expedia.ca/Northwest-Alabama-Vacation-Rentals.d6057725.Travel-Guide-VacationRentals)[Flights to Northwest Alabama](https://expedia.ca/Cheap-Flights-To-Northwest-Alabama.d6057725.Travel-Guide-Flights)[Things to do in Northwest Alabama](https://expedia.ca/Things-To-Do-In-Northwest-Alabama.d6057725.Travel-Guide-Activities)[Northwest Alabama Car Rentals](https://expedia.ca/Car-Rentals-In-Northwest-Alabama.d6057725.Car-Rental-Guide)[Northwest Alabama Vacation Packages](https://expedia.ca/Northwest-Alabama.d6057725.Destination-Travel-Guides) ![Frank Lloyd Wright Rosenbaum House which includes interior views and a house](https://a.travel-assets.com/findyours-php/viewfinder/images/res70/124000/124610-Florence-And-Vicinity.jpg?impolicy=fcrop&w=1200&h=500&q=medium) # Find luxury hotels in Northwest Alabama, AL ![calendar shield illustration](https://a.travel-assets.com/travel-assets-manager/pictogram-bex/light__calendar_shield.svg) ### Change your mind Book hotels with free cancellation ![deals illustration](https://a.travel-assets.com/travel-assets-manager/pictogram-bex/light__deals.svg) ### Treat yourself Sign in to save 10% or more on thousands of hotels [Sign in](https://www.expedia.ca/login) ![bed illustration](https://a.travel-assets.com/travel-assets-manager/pictogram-bex/light__bed.svg) ### Be picky Search almost a million properties worldwide ## Check availability on Northwest Alabama Luxury Hotels Tonight [Oct 5 - Oct 6](https://www.expedia.ca/Hotel-Search?regionId=6057725&startDate=2025-10-05&endDate=2025-10-06&adults=2&propertyStyle=LUXURY&rfrr=TG.LP.CheckPrices.Hotel&openPlayBack=true) Tomorrow [Oct 6 - Oct 7](https://www.expedia.ca/Hotel-Search?regionId=6057725&startDate=2025-10-06&endDate=2025-10-07&adults=2&propertyStyle=LUXURY&rfrr=TG.LP.CheckPrices.Hotel&openPlayBack=true) Next weekend [Oct 10 - Oct 12](https://www.expedia.ca/Hotel-Search?regionId=6057725&startDate=2025-10-10&endDate=2025-10-12&adults=2&propertyStyle=LUXURY&rfrr=TG.LP.CheckPrices.Hotel&openPlayBack=true) In two weeks [Oct 17 - Oct 19](https://www.expedia.ca/Hotel-Search?regionId=6057725&startDate=2025-10-17&endDate=2025-10-19&adults=2&propertyStyle=LUXURY&rfrr=TG.LP.CheckPrices.Hotel&openPlayBack=true) ## Top Northwest Alabama Luxury Hotels ![Lobby](https://images.trvl-media.com/lodging/2000000/1550000/1549300/1549240/46e8d6c3.jpg?impolicy=fcrop&w=357&h=201&p=1&q=medium) ![Front of property](https://images.trvl-media.com/lodging/2000000/1550000/1549300/1549240/d9cb9643.jpg?impolicy=fcrop&w=357&h=201&p=1&q=medium) ![Executive Studio Suite, 1 King Bed | Private kitchen](https://images.trvl-media.com/lodging/2000000/1550000/1549300/1549240/9b5fef1c.jpg?impolicy=fcrop&w=357&h=201&p=1&q=medium) ![Executive Studio Suite, 1 King Bed | Living area](https://images.trvl-media.com/lodging/2000000/1550000/1549300/1549240/758d5eba.jpg?impolicy=fcrop&w=357&h=201&p=1&q=medium) ### The ColdWater Inn Tuscumbia 9.0/10 Wonderful (581) "The property was very nice and the staff was friendly! " CA $103 CA $115 total includes taxes & fees Oct 14 - Oct 15 [](https://www.expedia.ca/Florence-Hotels-The-ColdWater-Inn.h1549240.Hotel-Information) ![Lobby](https://images.trvl-media.com/lodging/1000000/10000/8600/8599/c9b1fdcd.jpg?impolicy=fcrop&w=357&h=201&p=1&q=medium) ![Lobby](https://images.trvl-media.com/lodging/1000000/10000/8600/8599/48e30122.jpg?impolicy=fcrop&w=357&h=201&p=1&q=medium) ![Hallway](https://images.trvl-media.com/lodging/1000000/10000/8600/8599/d4d9e518.jpg?impolicy=fcrop&w=357&h=201&p=1&q=medium) ![Lobby sitting area](https://images.trvl-media.com/lodging/1000000/10000/8600/8599/2fdb7dd0.jpg?impolicy=fcrop&w=357&h=201&p=1&q=medium) ### Clarion Inn Sheffield Muscle Shoals Sheffield 7.4/10 Good (927) "Pet friendly " CA $113 CA $126 total includes taxes & fees Oct 13 - Oct 14 [](https://www.expedia.ca/Florence-Hotels-Clarion-Inn-Sheffield-Muscle-Shoals.h8599.Hotel-Information) ![Interior](https://images.trvl-media.com/lodging/1000000/70000/67100/67060/c13613f0.jpg?impolicy=fcrop&w=357&h=201&p=1&q=medium) ![Exterior](https://images.trvl-media.com/lodging/1000000/70000/67100/67060/ebcf39be.jpg?impolicy=fcrop&w=357&h=201&p=1&q=medium) ![Lobby](https://images.trvl-media.com/lodging/1000000/70000/67100/67060/d69651c5.jpg?impolicy=fcrop&w=357&h=201&p=1&q=medium) ![Free daily buffet breakfast](https://images.trvl-media.com/lodging/1000000/70000/67100/67060/e3eee8cf.jpg?impolicy=fcrop&w=357&h=201&p=1&q=medium) ### Baymont by Wyndham Florence/Muscle Shoals Florence 7.4/10 Good (845) "I liked how quiet it was and nice pool. " CA $94 CA $108 total includes taxes & fees Oct 6 - Oct 7 [](https://www.expedia.ca/Florence-Hotels-Baymont-By-Wyndham-FlorenceMuscle-Shoals.h67060.Hotel-Information) Lowest nightly price found within the past 24 hours based on a 1 night stay for 2 adults. Prices and availability subject to change. Additional terms may apply. [View all properties](https://expedia.ca/Hotel-Search?startDate=2025-10-19&endDate=2025-10-20®ionId=6057725&adults=2&star=50&sort=RECOMMENDED&openPlayBack=true) ## Top Northwest Alabama Hotel Reviews ![The ColdWater Inn](//images.trvl-media.com/lodging/2000000/1550000/1549300/1549240/46e8d6c3_y.jpg) ### The ColdWater Inn 10/10 Excellent "Beautiful property! Delicious hot breakfast. " [](https://expedia.ca/Florence-Hotels-The-ColdWater-Inn.h1549240.Hotel-Information) ![Clarion Inn Sheffield Muscle Shoals](//images.trvl-media.com/lodging/1000000/10000/8600/8599/c9b1fdcd_y.jpg) ### Clarion Inn Sheffield Muscle Shoals 8/10 Good "Pet friendly " [](https://expedia.ca/Florence-Hotels-Clarion-Inn-Sheffield-Muscle-Shoals.h8599.Hotel-Information) ![Baymont by Wyndham Florence/Muscle Shoals](//images.trvl-media.com/lodging/1000000/70000/67100/67060/c13613f0_y.jpg) ### Baymont by Wyndham Florence/Muscle Shoals 10/10 Excellent "Clean rooms" [](https://expedia.ca/Florence-Hotels-Baymont-By-Wyndham-FlorenceMuscle-Shoals.h67060.Hotel-Information) ## Explore a world of travel with Expedia - Lodging - Flights - Packages - Cars - More ways to book - [Alabama Shores Hotels](https://www.expedia.ca/Alabama-Shores-Hotels.d553248635975875941.Travel-Guide-Hotels) - [Resorts in Alabama Shores](https://www.expedia.ca/Alabama-Shores-Resort-Hotels.d553248635975875941-aaResortHotels.Travel-Guide-Accommodation) - 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