Title: Book the Best New Madrid LUXURY Hotels - Upscale Hotels in New Madrid, MO | Expedia.ca

[Hotels in New Madrid](https://expedia.ca/New-Madrid-Hotels.d3000445315.Travel-Guide-Hotels)[Vacation Rentals in New Madrid](https://expedia.ca/New-Madrid-Vacation-Rentals.d3000445315.Travel-Guide-VacationRentals)[New Madrid Car Rentals](https://expedia.ca/Car-Rentals-In-New-Madrid.d3000445315.Car-Rental-Guide)[New Madrid Vacation Packages](https://expedia.ca/New-Madrid.d3000445315.Destination-Travel-Guides)

![Mississippi River Walk at New Madrid.  A magnificent view of the Mississippi river from atop of the levee.  A steamboat is docked down river. . ](https://images.trvl-media.com/place/3000445315/970b11d9-266d-426a-9577-5e745e0939b7.jpg?impolicy=fcrop&w=1200&h=500&q=medium)

![](https://images.trvl-media.com/place/3000445315/970b11d9-266d-426a-9577-5e745e0939b7.jpg?impolicy=fcrop&w=1200&h=500&q=medium)

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## Check availability on New Madrid Luxury Hotels

Tonight

[Feb 3 - Feb 4](https://www.expedia.ca/Hotel-Search?regionId=3000445315&startDate=2026-02-03&endDate=2026-02-04&adults=2&propertyStyle=LUXURY&rfrr=TG.LP.CheckPrices.Hotel&openPlayBack=true&travelerType=luxury_property)

Tomorrow

[Feb 4 - Feb 5](https://www.expedia.ca/Hotel-Search?regionId=3000445315&startDate=2026-02-04&endDate=2026-02-05&adults=2&propertyStyle=LUXURY&rfrr=TG.LP.CheckPrices.Hotel&openPlayBack=true&travelerType=luxury_property)

This weekend

[Feb 6 - Feb 8](https://www.expedia.ca/Hotel-Search?regionId=3000445315&startDate=2026-02-06&endDate=2026-02-08&adults=2&propertyStyle=LUXURY&rfrr=TG.LP.CheckPrices.Hotel&openPlayBack=true&travelerType=luxury_property)

Next weekend

[Feb 13 - Feb 15](https://www.expedia.ca/Hotel-Search?regionId=3000445315&startDate=2026-02-13&endDate=2026-02-15&adults=2&propertyStyle=LUXURY&rfrr=TG.LP.CheckPrices.Hotel&openPlayBack=true&travelerType=luxury_property)

No exact matches found, but these alternatives could be just right

## Recommended hotels in New Madrid

![Exterior](https://images.trvl-media.com/lodging/121000000/120470000/120467300/120467279/w1060h720x0y199-6f809fb3.jpg?impolicy=fcrop&w=357&h=201&p=1&q=medium)

![Interior](https://images.trvl-media.com/lodging/121000000/120470000/120467300/120467279/w1050h1619x0y1-13beb152.jpg?impolicy=fcrop&w=357&h=201&p=1&q=medium)

![Smart TV](https://images.trvl-media.com/lodging/121000000/120470000/120467300/120467279/18e1eee4.jpg?impolicy=fcrop&w=357&h=201&p=1&q=medium)

![Fridge, microwave, oven, stovetop](https://images.trvl-media.com/lodging/121000000/120470000/120467300/120467279/w1080h1439x0y1-2bafdfca.jpg?impolicy=fcrop&w=357&h=201&p=1&q=medium)

### Spacious 3-bedroom 2 story house in New Madrid near boat ramp with a toy room!

[](https://www.expedia.ca/New-Madrid-Hotels-Spacious-3-Bedroom-2-Story-House-In-New-Madrid-Near-Boat-Ramp-With-A-Toy-Room.h120467279.Hotel-Information)

New Madrid

10/10

Exceptional

(1 review)

"The host was very quick to respond and so great to work with for on our stay. "

![United States](https://a.travel-assets.com/egds/marks/flags/us.svg)

Jessica S.

CA $272

CA $464 total

includes taxes & fees

Feb 12 - Feb 13

[](https://www.expedia.ca/New-Madrid-Hotels-Spacious-3-Bedroom-2-Story-House-In-New-Madrid-Near-Boat-Ramp-With-A-Toy-Room.h120467279.Hotel-Information)

![Exterior](https://images.trvl-media.com/lodging/26000000/25180000/25178200/25178175/77525d07.jpg?impolicy=fcrop&w=357&h=201&p=1&q=medium)

![In-room safe, free WiFi, bed sheets](https://images.trvl-media.com/lodging/26000000/25180000/25178200/25178175/cbe2898d.jpg?impolicy=fcrop&w=357&h=201&p=1&q=medium)

![Lobby](https://images.trvl-media.com/lodging/26000000/25180000/25178200/25178175/4abadc7f.jpg?impolicy=fcrop&w=357&h=201&p=1&q=medium)

![Exterior](https://images.trvl-media.com/lodging/26000000/25180000/25178200/25178175/d0739759.jpg?impolicy=fcrop&w=357&h=201&p=1&q=medium)

### Hampton Inn Sikeston

[](https://www.expedia.ca/Sikeston-Hotels-Hampton-Inn-Sikeston.h25178175.Hotel-Information)

Sikeston

9.0/10

Wonderful

(474 reviews)

"Great place for an overnight stay. I will be back!"

![United States](https://a.travel-assets.com/egds/marks/flags/us.svg)

Jenny

CA $136

CA $153 total

includes taxes & fees

Mar 1 - Mar 2

[](https://www.expedia.ca/Sikeston-Hotels-Hampton-Inn-Sikeston.h25178175.Hotel-Information)

![Exterior](https://images.trvl-media.com/lodging/9000000/8150000/8144200/8144106/3aa729da.jpg?impolicy=fcrop&w=357&h=201&p=1&q=medium)

![Free daily continental breakfast](https://images.trvl-media.com/lodging/9000000/8150000/8144200/8144106/1fd79e2a.jpg?impolicy=fcrop&w=357&h=201&p=1&q=medium)

![Hypo-allergenic bedding, down comforters, desk, iron/ironing board](https://images.trvl-media.com/lodging/9000000/8150000/8144200/8144106/4b95ba78.jpg?impolicy=fcrop&w=357&h=201&p=1&q=medium)

![Reception](https://images.trvl-media.com/lodging/9000000/8150000/8144200/8144106/58cb82c7.jpg?impolicy=fcrop&w=357&h=201&p=1&q=medium)

### Holiday Inn Express & Suites Sikeston Southwest by IHG

[](https://www.expedia.ca/Sikeston-Hotels-Holiday-Inn-Express-Suites-Sikeston-Southwest.h8144106.Hotel-Information)

Sikeston

8.6/10

Excellent

(447 reviews)

"Stay was excellent "

![United States](https://a.travel-assets.com/egds/marks/flags/us.svg)

Kourtney

CA $137

CA $155 total

includes taxes & fees

Feb 13 - Feb 14

[](https://www.expedia.ca/Sikeston-Hotels-Holiday-Inn-Express-Suites-Sikeston-Southwest.h8144106.Hotel-Information)

![Property amenity](https://images.trvl-media.com/lodging/112000000/111250000/111247500/111247451/f2cf9c54.jpg?impolicy=fcrop&w=357&h=201&p=1&q=medium)

![Indoor pool](https://images.trvl-media.com/lodging/112000000/111250000/111247500/111247451/27c728aa.jpg?impolicy=fcrop&w=357&h=201&p=1&q=medium)

![Fitness facility](https://images.trvl-media.com/lodging/112000000/111250000/111247500/111247451/e959f8b9.jpg?impolicy=fcrop&w=357&h=201&p=1&q=medium)

![Lobby lounge](https://images.trvl-media.com/lodging/112000000/111250000/111247500/111247451/c790aa73.jpg?impolicy=fcrop&w=357&h=201&p=1&q=medium)

### Fairfield Inn & Suites by Marriott Sikeston

[](https://www.expedia.ca/Fairfield-By-Marriott-Inn-Suites-Sikeston.h111247451.Hotel-Information)

Sikeston

9.2/10

Wonderful

(55 reviews)

"Clean rooms great staff"

![United States](https://a.travel-assets.com/egds/marks/flags/us.svg)

IRA

CA $138

CA $156 total

includes taxes & fees

Feb 12 - Feb 13

[](https://www.expedia.ca/Fairfield-By-Marriott-Inn-Suites-Sikeston.h111247451.Hotel-Information)

![Room, 1 Queen Bed, Non Smoking](https://images.trvl-media.com/lodging/109000000/108420000/108416700/108416635/5b4d84d0.jpg?impolicy=fcrop&w=357&h=201&p=1&q=medium)

![Lobby](https://images.trvl-media.com/lodging/109000000/108420000/108416700/108416635/0acd5e5c.jpg?impolicy=fcrop&w=357&h=201&p=1&q=medium)

![Exterior](https://images.trvl-media.com/lodging/109000000/108420000/108416700/108416635/ef46b494.jpg?impolicy=fcrop&w=357&h=201&p=1&q=medium)

![Lobby](https://images.trvl-media.com/lodging/109000000/108420000/108416700/108416635/7d06bc03.jpg?impolicy=fcrop&w=357&h=201&p=1&q=medium)

### Super 8 By Wyndham Marston

[](https://www.expedia.ca/Marston-Hotels-Super-8-By-Wyndham-Marston.h108416635.Hotel-Information)

Marston

8.0/10

Very good

(45 reviews)

"Great hotel, great staff"

![United States](https://a.travel-assets.com/egds/marks/flags/us.svg)

Dmitry

CA $88

CA $101 total

includes taxes & fees

Feb 6 - Feb 7

[](https://www.expedia.ca/Marston-Hotels-Super-8-By-Wyndham-Marston.h108416635.Hotel-Information)

![Property amenity](https://images.trvl-media.com/lodging/112000000/111250000/111247500/111247452/w3995h2667x0y0-6f8601de.jpg?impolicy=fcrop&w=357&h=201&p=1&q=medium)

![Indoor pool](https://images.trvl-media.com/lodging/112000000/111250000/111247500/111247452/fcfb42b9.jpg?impolicy=fcrop&w=357&h=201&p=1&q=medium)

![Exterior](https://images.trvl-media.com/lodging/112000000/111250000/111247500/111247452/w4000h2662x0y0-82d0e62d.jpg?impolicy=fcrop&w=357&h=201&p=1&q=medium)

![Lobby lounge](https://images.trvl-media.com/lodging/112000000/111250000/111247500/111247452/de7767c3.jpg?impolicy=fcrop&w=357&h=201&p=1&q=medium)

### TownePlace Suites by Marriott Sikeston

[](https://www.expedia.ca/Towneplace-Suites-By-Marriott-Sikeston.h111247452.Hotel-Information)

Sikeston

9.2/10

Wonderful

(12 reviews)

"Great hotel! Very clean, quiet, plenty of amenities, pool was clean, breakfast in the morning was good with lots of options. I would definitely stay here again. "

![United States](https://a.travel-assets.com/egds/marks/flags/us.svg)

Scott

CA $196

CA $222 total

includes taxes & fees

Mar 5 - Mar 6

[](https://www.expedia.ca/Towneplace-Suites-By-Marriott-Sikeston.h111247452.Hotel-Information)

![Premier Room, 1 Bedroom, Non Smoking](https://images.trvl-media.com/lodging/39000000/38980000/38979800/38979739/2d9e6936.jpg?impolicy=fcrop&w=357&h=201&p=1&q=medium)

![Front of property](https://images.trvl-media.com/lodging/39000000/38980000/38979800/38979739/91bb8871.jpg?impolicy=fcrop&w=357&h=201&p=1&q=medium)

![Premier Room, 1 Bedroom, Non Smoking | Bathroom](https://images.trvl-media.com/lodging/39000000/38980000/38979800/38979739/5fa7b845.jpg?impolicy=fcrop&w=357&h=201&p=1&q=medium)

![Deluxe Room, 1 King Bed, Non Smoking](https://images.trvl-media.com/lodging/39000000/38980000/38979800/38979739/a77daa89.jpg?impolicy=fcrop&w=357&h=201&p=1&q=medium)

### New Orleans Inn Portageville 

[](https://www.expedia.ca/Hayti-Hotels-New-Orleans-Inn.h38979739.Hotel-Information)

Portageville

8.0/10

Very good

(738 reviews)

"Parking was good, staff was great "

![United States](https://a.travel-assets.com/egds/marks/flags/us.svg)

Corey

[](https://www.expedia.ca/Hayti-Hotels-New-Orleans-Inn.h38979739.Hotel-Information)

![Smart TV](https://images.trvl-media.com/lodging/102000000/101880000/101879200/101879138/0d61a825.jpg?impolicy=fcrop&w=357&h=201&p=1&q=medium)

![Fridge, microwave, oven, stovetop](https://images.trvl-media.com/lodging/102000000/101880000/101879200/101879138/5fe9a626.jpg?impolicy=fcrop&w=357&h=201&p=1&q=medium)

![Interior](https://images.trvl-media.com/lodging/102000000/101880000/101879200/101879138/98a7dc87.jpg?impolicy=fcrop&w=357&h=201&p=1&q=medium)

![1 bedroom, WiFi, bed sheets](https://images.trvl-media.com/lodging/102000000/101880000/101879200/101879138/8341e2b2.jpg?impolicy=fcrop&w=357&h=201&p=1&q=medium)

### Tiny house on the lake with tv free internet walk shower 

[](https://www.expedia.ca/Tiptonville-Hotels-Tiny-House-On-The-Lake-With-A-Seventy-Five-Inch-T-V-Free-Internet-Walk-Shower.h101879138.Hotel-Information)

Tiptonville

10/10

Exceptional

(1 review)

"Dave was very accommodating and the home was clean."

![United States](https://a.travel-assets.com/egds/marks/flags/us.svg)

Katherine P.

CA $185

CA $342 total

includes taxes & fees

Feb 4 - Feb 5

[](https://www.expedia.ca/Tiptonville-Hotels-Tiny-House-On-The-Lake-With-A-Seventy-Five-Inch-T-V-Free-Internet-Walk-Shower.h101879138.Hotel-Information)

![Standard Room, 2 Double Beds, Non Smoking](https://images.trvl-media.com/lodging/17000000/16770000/16770000/16769945/543bd231.jpg?impolicy=fcrop&w=357&h=201&p=1&q=medium)

![Exterior](https://images.trvl-media.com/lodging/17000000/16770000/16770000/16769945/e0fa396b.jpg?impolicy=fcrop&w=357&h=201&p=1&q=medium)

![Property grounds](https://images.trvl-media.com/lodging/17000000/16770000/16770000/16769945/45782657.jpg?impolicy=fcrop&w=357&h=201&p=1&q=medium)

![Handicap Room](https://images.trvl-media.com/lodging/17000000/16770000/16770000/16769945/6128b6d5.jpg?impolicy=fcrop&w=357&h=201&p=1&q=medium)

### Reelfoot Lake Inn

[](https://www.expedia.ca/Union-City-Hotels-Reelfoot-Lake-Inn.h16769945.Hotel-Information)

Tiptonville

7.2/10

Good

(465 reviews)

"Nice in clean room"

![United States](https://a.travel-assets.com/egds/marks/flags/us.svg)

Jayla

CA $79

CA $91 total

includes taxes & fees

Mar 2 - Mar 3

[](https://www.expedia.ca/Union-City-Hotels-Reelfoot-Lake-Inn.h16769945.Hotel-Information)

![Exterior](https://images.trvl-media.com/lodging/90000000/89880000/89872800/89872735/71b3c54d.jpg?impolicy=fcrop&w=357&h=201&p=1&q=medium)

![Smart TV, books](https://images.trvl-media.com/lodging/90000000/89880000/89872800/89872735/df2099b4.jpg?impolicy=fcrop&w=357&h=201&p=1&q=medium)

![Smart TV, books](https://images.trvl-media.com/lodging/90000000/89880000/89872800/89872735/70fd95a5.jpg?impolicy=fcrop&w=357&h=201&p=1&q=medium)

![Outdoor dining](https://images.trvl-media.com/lodging/90000000/89880000/89872800/89872735/96df576d.jpg?impolicy=fcrop&w=357&h=201&p=1&q=medium)

### Great location just across the street from Reelfoot Lake close to boat ramps

[](https://www.expedia.ca/Hornbeak-Hotels-Great-Location-Just-Across-The-Street-From-Reelfoot-Lake-Close-To-Boat-Ramps.h89872735.Hotel-Information)

Hornbeak

9.8/10

Exceptional

(81 reviews)

"As advertised, it was cozy and pleasant. "

![United States](https://a.travel-assets.com/egds/marks/flags/us.svg)

Nathan B.

CA $123

CA $229 total

includes taxes & fees

Feb 7 - Feb 8

[](https://www.expedia.ca/Hornbeak-Hotels-Great-Location-Just-Across-The-Street-From-Reelfoot-Lake-Close-To-Boat-Ramps.h89872735.Hotel-Information)

Lowest nightly price found within the past 24 hours based on a 1 night stay for 2 adults. Prices and availability subject to change. Additional terms may apply.

[View all properties](https://expedia.ca/Hotel-Search?startDate=2026-02-17&endDate=2026-02-18&regionId=3000445315&adults=2&sort=LUXURY&star=40,50&openPlayBack=true)

## Top New Madrid Hotel Reviews

## Frequently asked questions

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