Find Spa Hotels in Mytilene from CA $103

Book one of our fantastic spa hotels and pamper yourself from the moment you arrive. Check out the museums and churches in Mytilene—your cultural tour starts here. Enjoy the architecture and sea views during your vacation. Spa hotels are a great way to break out of your routine and add a layer of luxury to your weekend away.

Theofilos Paradise Boutique Hotel is a top boutique spa hotel featuring a pool, a rooftop terrace, and a bar. Treat yourself to a massage at the on-site spa. Another popular spa hotel in Mytilene is Mythical Coast Wellness Retreat.

Among Expedia’s 61 accommodation options in Mytilene, there are 2 spa hotels.

When you’re in Mytilene, enjoy exploring the sights and attractions here including Port of Mytilene, Mytilini Castle, and Church of Taxiarches. If you have a bit of extra time while you’re in the area, you might want to check out Roman Aqueduct at Moria and Museum of the Memorial of the Refugees of 1922.

Spa hotels in Mytilene feature full on-site spas offering services like facials and a range of beauty treatments. Some also provide a selection of in-room treatments for the ultimate luxury. Spa hotels are ideal if you are looking for some R&R during your vacation.