Title: Book the Best Museum District LUXURY Hotels - Upscale Hotels in Museum District, Houston | Expedia.ca [Vacation Rentals in Houston](https://expedia.ca/Houston-Vacation-Rentals.d178265.Travel-Guide-VacationRentals)[Flights to Houston](https://expedia.ca/Cheap-Flights-To-Houston.d178265.Travel-Guide-Flights)[Things to do in Houston](https://expedia.ca/Things-To-Do-In-Houston.d178265.Travel-Guide-Activities)[Museum District Car Rentals](https://expedia.ca/Car-Rentals-In-Museum-District.d6164045.Car-Rental-Guide)[Museum District Vacations](https://expedia.ca/Museum-District.d6164045.Destination-Travel-Guides) ![Houston Natural Science Museum featuring heritage elements and interior views](https://images.trvl-media.com/place/501256/4e455af8-0f6d-48a6-81ba-874182e2abef.jpg?impolicy=fcrop&w=1200&h=500&q=medium) # Find Luxury Hotels in Museum District, Houston - ![](https://a.travel-assets.com/travel-assets-manager/pictogram-bex/light__calendar_shield.svg) ### Change your mind Book hotels with free cancellation - ![](https://a.travel-assets.com/travel-assets-manager/pictogram-bex/light__deals.svg) ### Treat yourself Sign in to save 10% or more on thousands of hotels [Sign in](https://www.expedia.ca/login) - ![](https://a.travel-assets.com/travel-assets-manager/pictogram-bex/light__bed.svg) ### Be picky Search almost a million properties worldwide ## Check availability on Museum District Luxury Hotels Tonight [Jan 4 - Jan 5](https://www.expedia.ca/Hotel-Search?regionId=6164045&startDate=2026-01-04&endDate=2026-01-05&adults=2&propertyStyle=LUXURY&rfrr=TG.LP.CheckPrices.Hotel&openPlayBack=true&travelerType=luxury_property) Tomorrow [Jan 5 - Jan 6](https://www.expedia.ca/Hotel-Search?regionId=6164045&startDate=2026-01-05&endDate=2026-01-06&adults=2&propertyStyle=LUXURY&rfrr=TG.LP.CheckPrices.Hotel&openPlayBack=true&travelerType=luxury_property) Next weekend [Jan 9 - Jan 11](https://www.expedia.ca/Hotel-Search?regionId=6164045&startDate=2026-01-09&endDate=2026-01-11&adults=2&propertyStyle=LUXURY&rfrr=TG.LP.CheckPrices.Hotel&openPlayBack=true&travelerType=luxury_property) In two weeks [Jan 16 - Jan 18](https://www.expedia.ca/Hotel-Search?regionId=6164045&startDate=2026-01-16&endDate=2026-01-18&adults=2&propertyStyle=LUXURY&rfrr=TG.LP.CheckPrices.Hotel&openPlayBack=true&travelerType=luxury_property) ## Our top choices for Museum District luxury hotels ![Buffet breakfast on weekends (USD 18 per person)](https://images.trvl-media.com/lodging/1000000/10000/5900/5886/ed52898c.jpg?impolicy=fcrop&w=357&h=201&p=1&q=medium) ![Hallway](https://images.trvl-media.com/lodging/1000000/10000/5900/5886/55b4202e.jpg?impolicy=fcrop&w=357&h=201&p=1&q=medium) ![Reception](https://images.trvl-media.com/lodging/1000000/10000/5900/5886/e0bf3fba.jpg?impolicy=fcrop&w=357&h=201&p=1&q=medium) ![Reception](https://images.trvl-media.com/lodging/1000000/10000/5900/5886/8942d8c2.jpg?impolicy=fcrop&w=357&h=201&p=1&q=medium) ### Doubletree by Hilton Houston Hobby Airport [](https://www.expedia.ca/Houston-Hotels-Doubletree-By-Hilton-Houston-Hobby-Airport.h5886.Hotel-Information) Southeast Houston 8.8/10 Excellent (1008) "Great room, great service and wonderful people. " ![United States](https://a.travel-assets.com/egds/marks/flags/us.svg) Stanley CA $123 CA $145 total includes taxes & fees Jan 16 - Jan 17 [](https://www.expedia.ca/Houston-Hotels-Doubletree-By-Hilton-Houston-Hobby-Airport.h5886.Hotel-Information) ![Premium bedding, minibar, in-room safe, individually decorated](https://images.trvl-media.com/lodging/59000000/58990000/58985900/58985846/40a5bc26.jpg?impolicy=fcrop&w=357&h=201&p=1&q=medium) ![50-inch Smart TV with cable channels, TV, Netflix](https://images.trvl-media.com/lodging/59000000/58990000/58985900/58985846/w3836h2556x4y4-af1501b3.jpg?impolicy=fcrop&w=357&h=201&p=1&q=medium) ![Lobby](https://images.trvl-media.com/lodging/59000000/58990000/58985900/58985846/w3837h2505x3y0-1cfabad9.jpg?impolicy=fcrop&w=357&h=201&p=1&q=medium) ![Lobby](https://images.trvl-media.com/lodging/59000000/58990000/58985900/58985846/db7ae93f.jpg?impolicy=fcrop&w=357&h=201&p=1&q=medium) ### Blossom Hotel Houston, Curio Collection by Hilton [](https://www.expedia.ca/Houston-Hotels-Blossom-Hotel-Houston.h58985846.Hotel-Information) Texas Medical Center 9.0/10 Wonderful (3650) "Great Hotel! " ![United States](https://a.travel-assets.com/egds/marks/flags/us.svg) Delilah CA $179 CA $209 total includes taxes & fees Jan 18 - Jan 19 [](https://www.expedia.ca/Houston-Hotels-Blossom-Hotel-Houston.h58985846.Hotel-Information) ![Cocktail bar](https://images.trvl-media.com/lodging/19000000/18470000/18465900/18465864/414eab2e.jpg?impolicy=fcrop&w=357&h=201&p=1&q=medium) ![Meeting facility](https://images.trvl-media.com/lodging/19000000/18470000/18465900/18465864/dedc2cf7.jpg?impolicy=fcrop&w=357&h=201&p=1&q=medium) ![Lobby](https://images.trvl-media.com/lodging/19000000/18470000/18465900/18465864/f47077d2.jpg?impolicy=fcrop&w=357&h=201&p=1&q=medium) ![Rooftop terrace](https://images.trvl-media.com/lodging/19000000/18470000/18465900/18465864/04fe0eec.jpg?impolicy=fcrop&w=357&h=201&p=1&q=medium) ### Le Meridien Houston Downtown [](https://www.expedia.ca/Houston-Hotels-Le-Meridien-Houston-Downtown.h18465864.Hotel-Information) Downtown Houston 8.8/10 Excellent (1004) "Great hotel staff. " ![United States](https://a.travel-assets.com/egds/marks/flags/us.svg) Camille CA $197 CA $230 total includes taxes & fees Jan 5 - Jan 6 [](https://www.expedia.ca/Houston-Hotels-Le-Meridien-Houston-Downtown.h18465864.Hotel-Information) ![Outdoor pool, pool umbrellas, sun loungers](https://images.trvl-media.com/lodging/4000000/3050000/3040400/3040388/d7cbf17e.jpg?impolicy=fcrop&w=357&h=201&p=1&q=medium) ![Meeting facility](https://images.trvl-media.com/lodging/4000000/3050000/3040400/3040388/4e94329f.jpg?impolicy=fcrop&w=357&h=201&p=1&q=medium) ![Lobby](https://images.trvl-media.com/lodging/4000000/3050000/3040400/3040388/f0767e22.jpg?impolicy=fcrop&w=357&h=201&p=1&q=medium) ![Exterior](https://images.trvl-media.com/lodging/4000000/3050000/3040400/3040388/5f7e715f.jpg?impolicy=fcrop&w=357&h=201&p=1&q=medium) ### Houston Marriott Energy Corridor [](https://www.expedia.ca/Houston-Hotels-Houston-Marriott-Energy-Corridor.h3040388.Hotel-Information) Energy Corridor 8.6/10 Excellent (876) "Our rooms are clean, very good with the reception, check in soo easy! " ![United States](https://a.travel-assets.com/egds/marks/flags/us.svg) Yessenia CA $115 CA $137 total includes taxes & fees Jan 9 - Jan 10 [](https://www.expedia.ca/Houston-Hotels-Houston-Marriott-Energy-Corridor.h3040388.Hotel-Information) ![Outdoor pool, open 6:00 AM to 10:00 PM, pool umbrellas, sun loungers](https://images.trvl-media.com/lodging/11000000/10630000/10620700/10620692/9a708987.jpg?impolicy=fcrop&w=357&h=201&p=1&q=medium) ![1 bedroom, hypo-allergenic bedding, in-room safe, desk](https://images.trvl-media.com/lodging/11000000/10630000/10620700/10620692/e4ab6d84.jpg?impolicy=fcrop&w=357&h=201&p=1&q=medium) ![2 bars/lounges, poolside bar](https://images.trvl-media.com/lodging/11000000/10630000/10620700/10620692/5138e12a.jpg?impolicy=fcrop&w=357&h=201&p=1&q=medium) ![Lobby](https://images.trvl-media.com/lodging/11000000/10630000/10620700/10620692/b1e04b0e.jpg?impolicy=fcrop&w=357&h=201&p=1&q=medium) ### Hyatt Regency Houston/Galleria [](https://www.expedia.ca/Houston-Hotels-Hyatt-Regency-HoustonGalleria.h10620692.Hotel-Information) The Galleria 9.0/10 Wonderful (1197) "Clean rooms great location helpful front desk staff " ![United States](https://a.travel-assets.com/egds/marks/flags/us.svg) Kim CA $191 CA $265 total includes taxes & fees Jan 5 - Jan 6 [](https://www.expedia.ca/Houston-Hotels-Hyatt-Regency-HoustonGalleria.h10620692.Hotel-Information) ![Sundeck](https://images.trvl-media.com/lodging/1000000/30000/25200/25188/294f3d50.jpg?impolicy=fcrop&w=357&h=201&p=1&q=medium) ![View from room](https://images.trvl-media.com/lodging/1000000/30000/25200/25188/f8ddb5e6.jpg?impolicy=fcrop&w=357&h=201&p=1&q=medium) ![Premium bedding, in-room safe, desk, laptop workspace](https://images.trvl-media.com/lodging/1000000/30000/25200/25188/12af8c32.jpg?impolicy=fcrop&w=357&h=201&p=1&q=medium) ![Lobby](https://images.trvl-media.com/lodging/1000000/30000/25200/25188/8964faa3.jpg?impolicy=fcrop&w=357&h=201&p=1&q=medium) ### Hilton Houston Plaza/Medical Center [](https://www.expedia.ca/Houston-Hotels-Hilton-Houston-Plaza-Medical-Center.h25188.Hotel-Information) Texas Medical Center 8.4/10 Very good (1809) "The hotel was great and convenient. Easy check in an check out. Will definitely stay again. " ![United States](https://a.travel-assets.com/egds/marks/flags/us.svg) Allison CA $151 CA $178 total includes taxes & fees Jan 9 - Jan 10 [](https://www.expedia.ca/Houston-Hotels-Hilton-Houston-Plaza-Medical-Center.h25188.Hotel-Information) ![Reception](https://images.trvl-media.com/lodging/24000000/23840000/23830900/23830866/e83f776d.jpg?impolicy=fcrop&w=357&h=201&p=1&q=medium) ![Property amenity](https://images.trvl-media.com/lodging/24000000/23840000/23830900/23830866/efa6f907.jpg?impolicy=fcrop&w=357&h=201&p=1&q=medium) ![Premium bedding, in-room safe, individually furnished, desk](https://images.trvl-media.com/lodging/24000000/23840000/23830900/23830866/b72d00fa.jpg?impolicy=fcrop&w=357&h=201&p=1&q=medium) ![Exterior](https://images.trvl-media.com/lodging/24000000/23840000/23830900/23830866/29e4bd94.jpg?impolicy=fcrop&w=357&h=201&p=1&q=medium) ### InterContinental Houston by IHG [](https://www.expedia.ca/Houston-Hotels-InterContinental-Houston-Medical-Center.h23830866.Hotel-Information) Texas Medical Center 9.2/10 Wonderful (1003) "Very clean room very polite staff" ![United States](https://a.travel-assets.com/egds/marks/flags/us.svg) David CA $214 CA $278 total includes taxes & fees Jan 18 - Jan 19 [](https://www.expedia.ca/Houston-Hotels-InterContinental-Houston-Medical-Center.h23830866.Hotel-Information) ![Lobby](https://images.trvl-media.com/lodging/2000000/1160000/1157000/1156923/44a9a3fd.jpg?impolicy=fcrop&w=357&h=201&p=1&q=medium) ![Exterior](https://images.trvl-media.com/lodging/2000000/1160000/1157000/1156923/aa7fafd4.jpg?impolicy=fcrop&w=357&h=201&p=1&q=medium) ![Reception](https://images.trvl-media.com/lodging/2000000/1160000/1157000/1156923/76e7278c.jpg?impolicy=fcrop&w=357&h=201&p=1&q=medium) ![Reception](https://images.trvl-media.com/lodging/2000000/1160000/1157000/1156923/c1fa2b90.jpg?impolicy=fcrop&w=357&h=201&p=1&q=medium) ### Club Quarters Hotel Downtown, Houston [](https://www.expedia.ca/Houston-Hotels-Club-Quarters-Hotel-In-Houston.h1156923.Hotel-Information) Downtown Houston 8.4/10 Very good (3996) "Rooms were great and the staff was absolutely amazing. " ![United States](https://a.travel-assets.com/egds/marks/flags/us.svg) Elmer CA $109 CA $127 total includes taxes & fees Jan 12 - Jan 13 [](https://www.expedia.ca/Houston-Hotels-Club-Quarters-Hotel-In-Houston.h1156923.Hotel-Information) ![Exterior](https://images.trvl-media.com/lodging/1000000/880000/878700/878652/9874e960.jpg?impolicy=fcrop&w=357&h=201&p=1&q=medium) ![Egyptian cotton sheets, premium bedding, pillowtop beds, in-room safe](https://images.trvl-media.com/lodging/1000000/880000/878700/878652/w3836h2556x4y4-d736e03c.jpg?impolicy=fcrop&w=357&h=201&p=1&q=medium) ![Staircase](https://images.trvl-media.com/lodging/1000000/880000/878700/878652/5506d9bf.jpg?impolicy=fcrop&w=357&h=201&p=1&q=medium) ![Suite, 1 King Bed, City View | View from room](https://images.trvl-media.com/lodging/1000000/880000/878700/878652/a6761ef3.jpg?impolicy=fcrop&w=357&h=201&p=1&q=medium) ### The Royal Sonesta Houston Galleria [](https://www.expedia.ca/Houston-Hotels-Royal-Sonesta-Houston-Galleria.h878652.Hotel-Information) The Galleria 8.4/10 Very good (1518) "Staff members very nice, hotel as a whole very clean " ![United States](https://a.travel-assets.com/egds/marks/flags/us.svg) Lester CA $150 CA $176 total includes taxes & fees Jan 8 - Jan 9 [](https://www.expedia.ca/Houston-Hotels-Royal-Sonesta-Houston-Galleria.h878652.Hotel-Information) ![Egyptian cotton sheets, premium bedding, pillowtop beds, in-room safe](https://images.trvl-media.com/lodging/21000000/20060000/20052400/20052335/9a08534e.jpg?impolicy=fcrop&w=357&h=201&p=1&q=medium) ![Exterior](https://images.trvl-media.com/lodging/21000000/20060000/20052400/20052335/2515d4a2.jpg?impolicy=fcrop&w=357&h=201&p=1&q=medium) ![Egyptian cotton sheets, premium bedding, pillowtop beds, in-room safe](https://images.trvl-media.com/lodging/21000000/20060000/20052400/20052335/3737c7cc.jpg?impolicy=fcrop&w=357&h=201&p=1&q=medium) ![50-inch LED TV with cable channels, TV](https://images.trvl-media.com/lodging/21000000/20060000/20052400/20052335/046a8fa8.jpg?impolicy=fcrop&w=357&h=201&p=1&q=medium) ### The Laura Hotel, Houston Downtown, Autograph Collection [](https://www.expedia.ca/Houston-Hotels-Alessandra-Hotel.h20052335.Hotel-Information) Downtown Houston 9.0/10 Wonderful (1055) "clean hotel, perfect spot in houston" ![United States](https://a.travel-assets.com/egds/marks/flags/us.svg) Alexa CA $213 CA $292 total includes taxes & fees Jan 5 - Jan 6 [](https://www.expedia.ca/Houston-Hotels-Alessandra-Hotel.h20052335.Hotel-Information) Lowest nightly price found within the past 24 hours based on a 1 night stay for 2 adults. Prices and availability subject to change. Additional terms may apply. [View all properties](https://expedia.ca/Hotel-Search?startDate=2026-01-18&endDate=2026-01-19®ionId=6164045&adults=2&sort=LUXURY&star=40,50&openPlayBack=true) ## Top Museum District Hotel Reviews ![Magnolia Hotel Houston, A Tribute Portfolio Hotel](https://images.trvl-media.com/lodging/1000000/910000/907500/907459/0b2adb37_y.jpg) ### Magnolia Hotel Houston, A Tribute Portfolio Hotel 10/10 Excellent "It was good " [](https://expedia.ca/Houston-Hotels-Magnolia-Hotel-Houston.h907459.Hotel-Information) ![The Royal Sonesta Houston Galleria](https://images.trvl-media.com/lodging/1000000/880000/878700/878652/9874e960_y.jpg) ### The Royal Sonesta Houston Galleria 10/10 Excellent "All the above, was on point" [](https://expedia.ca/Houston-Hotels-Royal-Sonesta-Houston-Galleria.h878652.Hotel-Information) ![Heritage Place Houston Brookhollow](https://images.trvl-media.com/lodging/1000000/10000/6300/6298/90f3bec7_y.jpg) ### Heritage Place Houston Brookhollow 10/10 Excellent "Very nice staff" [](https://expedia.ca/Houston-Hotels-Heritage-Place-Houston-Brookhollow.h6298.Hotel-Information) ![Hilton Americas-Houston](https://images.trvl-media.com/lodging/1000000/980000/976200/976144/09dd0b59_y.jpg) ### Hilton Americas-Houston 10/10 Excellent "Excellent experience, friendly an add even when busy “New Years Eve”. Close to our venue, rooftop bar had fantastic city views and a cool vibe. " [](https://expedia.ca/Houston-Hotels-Hilton-Americas-Houston.h976144.Hotel-Information) ![Club Quarters Hotel Downtown, Houston](https://images.trvl-media.com/lodging/2000000/1160000/1157000/1156923/44a9a3fd_y.jpg) ### Club Quarters Hotel Downtown, Houston 10/10 Excellent "Very nice people, really neat old building. Fair price for a stay. Good restaurants in the area and the one at the hotel was very good. " [](https://expedia.ca/Houston-Hotels-Club-Quarters-Hotel-In-Houston.h1156923.Hotel-Information) ![The Westin Galleria Houston](https://images.trvl-media.com/lodging/1000000/20000/11200/11117/b45a8086_y.jpg) ### The Westin Galleria Houston 10/10 Excellent "Best hotel I have stayed at in some time. Will definitely return again! " [](https://expedia.ca/Houston-Hotels-The-Westin-Galleria-Houston.h11117.Hotel-Information) ![DoubleTree by Hilton Hotel Houston - Greenway Plaza](https://images.trvl-media.com/lodging/1000000/30000/20200/20177/682ca680_y.jpg) ### DoubleTree by Hilton Hotel Houston - Greenway Plaza 10/10 Excellent "It was amazing " [](https://expedia.ca/Houston-Hotels-DoubleTree-By-Hilton-Hotel-Houston-Greenway-Plaza.h20177.Hotel-Information) ![Hilton Houston Plaza/Medical Center](https://images.trvl-media.com/lodging/1000000/30000/25200/25188/294f3d50_y.jpg) ### Hilton Houston Plaza/Medical Center 10/10 Excellent "Everything was great " [](https://expedia.ca/Houston-Hotels-Hilton-Houston-Plaza-Medical-Center.h25188.Hotel-Information) ![Omni Houston Hotel](https://images.trvl-media.com/lodging/1000000/20000/17800/17746/37423ee4_y.jpg) ### Omni Houston Hotel 10/10 Excellent "Excellent service, spotless, easy check in and superior staff. " [](https://expedia.ca/Houston-Hotels-Omni-Houston-Hotel.h17746.Hotel-Information) ## Frequently asked questions ### Are you searching for a great accommodation for your luxury getaway to Museum District? ### What's there to see and do in Museum District? ### How can I get around Museum District? ## Explore a world of travel with Expedia - Lodging - Flights - Packages - Cars - Other - More ways to book - [2 Star Hotels in South Central Houston ](https://www.expedia.ca/2Star-South-Central-Houston-Houston-Hotels.s20-n553248635976476176-0.Travel-Guide-Filter-Hotels) - [Hotels near Children's Museum of Houston ](https://www.expedia.ca/Childrens-Museum-Of-Houston-Hotels.0-l6082211-0.Travel-Guide-Filter-Hotels) - [Hotels near Continental Club ](https://www.expedia.ca/Continental-Club-Hotels.0-l553248621533124447-0.Travel-Guide-Filter-Hotels) - [Downtown Houston Hotels ](https://www.expedia.ca/Downtown-Houston-Houston-Hotels.0-n800037-0.Travel-Guide-Filter-Hotels) - [B&B in Dryden/TMC Station ](https://www.expedia.ca/DrydenTMC-Station-Bed-And-Breakfast.d6211670-aaBedAndBreakfast.Travel-Guide-Accommodation) - 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