Title: Book the Best Museum District LUXURY Hotels - Upscale Hotels in Museum District, Houston | Expedia.ca [Vacation Rentals in Houston](https://expedia.ca/Houston-Vacation-Rentals.d178265.Travel-Guide-VacationRentals)[Flights to Houston](https://expedia.ca/Cheap-Flights-To-Houston.d178265.Travel-Guide-Flights)[Things to do in Houston](https://expedia.ca/Things-To-Do-In-Houston.d178265.Travel-Guide-Activities)[Museum District Car Rentals](https://expedia.ca/Car-Rentals-In-Museum-District.d6164045.Car-Rental-Guide)[Museum District Vacations](https://expedia.ca/Museum-District.d6164045.Destination-Travel-Guides) ![Houston Natural Science Museum featuring heritage elements and interior views](https://images.trvl-media.com/place/501256/4e455af8-0f6d-48a6-81ba-874182e2abef.jpg?impolicy=fcrop&w=1200&h=500&q=medium) ![](https://images.trvl-media.com/place/501256/4e455af8-0f6d-48a6-81ba-874182e2abef.jpg?impolicy=fcrop&w=1200&h=500&q=medium) - ![](https://a.travel-assets.com/travel-assets-manager/pictogram-bex/light__calendar_shield.svg) ### Change your mind Book hotels with free cancellation - ![](https://a.travel-assets.com/travel-assets-manager/pictogram-bex/light__deals.svg) ### Treat yourself Sign in to save 10% or more on thousands of hotels [Sign in](https://www.expedia.ca/login) - ![](https://a.travel-assets.com/travel-assets-manager/pictogram-bex/light__bed.svg) ### Be picky Search almost a million properties worldwide ## Check availability on Museum District Luxury Hotels Tonight [Feb 5 - Feb 6](https://www.expedia.ca/Hotel-Search?regionId=6164045&startDate=2026-02-05&endDate=2026-02-06&adults=2&propertyStyle=LUXURY&rfrr=TG.LP.CheckPrices.Hotel&openPlayBack=true&travelerType=luxury_property) Tomorrow [Feb 6 - Feb 7](https://www.expedia.ca/Hotel-Search?regionId=6164045&startDate=2026-02-06&endDate=2026-02-07&adults=2&propertyStyle=LUXURY&rfrr=TG.LP.CheckPrices.Hotel&openPlayBack=true&travelerType=luxury_property) This weekend [Feb 6 - Feb 8](https://www.expedia.ca/Hotel-Search?regionId=6164045&startDate=2026-02-06&endDate=2026-02-08&adults=2&propertyStyle=LUXURY&rfrr=TG.LP.CheckPrices.Hotel&openPlayBack=true&travelerType=luxury_property) Next weekend [Feb 13 - Feb 15](https://www.expedia.ca/Hotel-Search?regionId=6164045&startDate=2026-02-13&endDate=2026-02-15&adults=2&propertyStyle=LUXURY&rfrr=TG.LP.CheckPrices.Hotel&openPlayBack=true&travelerType=luxury_property) ## Our top choices for Museum District luxury hotels ![Premium bedding, pillowtop beds, minibar, in-room safe](https://images.trvl-media.com/lodging/1000000/10000/3400/3306/0f950f88.jpg?impolicy=fcrop&w=357&h=201&p=1&q=medium) ![Restaurant](https://images.trvl-media.com/lodging/1000000/10000/3400/3306/2eef6b93.jpg?impolicy=fcrop&w=357&h=201&p=1&q=medium) ![Premium bedding, pillowtop beds, minibar, in-room safe](https://images.trvl-media.com/lodging/1000000/10000/3400/3306/53ee2707.jpg?impolicy=fcrop&w=357&h=201&p=1&q=medium) ![Junior Suite, 1 King Bed](https://images.trvl-media.com/lodging/1000000/10000/3400/3306/8df6fdc6.jpg?impolicy=fcrop&w=357&h=201&p=1&q=medium) ### Hotel Zaza Houston Museum District [](https://www.expedia.ca/Houston-Hotels-Hotel-Zaza-Houston-Museum-District.h3306.Hotel-Information) South Central Houston 9.0/10 Wonderful (1,898 reviews) - Tranquil luxury near Houston's Museum District features a full-service spa, outdoor pool, and indulgent champagne service. CA $344 CA $466 total includes taxes & fees Feb 12 - Feb 13 [](https://www.expedia.ca/Houston-Hotels-Hotel-Zaza-Houston-Museum-District.h3306.Hotel-Information) ![3 bars/lounges, lobby lounge](https://images.trvl-media.com/lodging/1000000/20000/17800/17746/92605085.jpg?impolicy=fcrop&w=357&h=201&p=1&q=medium) ![3 bars/lounges, lobby lounge](https://images.trvl-media.com/lodging/1000000/20000/17800/17746/1b15f0cf.jpg?impolicy=fcrop&w=357&h=201&p=1&q=medium) ![Lake](https://images.trvl-media.com/lodging/1000000/20000/17800/17746/w8869h6643x0y3-810eb54b.jpg?impolicy=fcrop&w=357&h=201&p=1&q=medium) ![Interior](https://images.trvl-media.com/lodging/1000000/20000/17800/17746/79071c33.jpg?impolicy=fcrop&w=357&h=201&p=1&q=medium) ### Omni Houston Hotel [](https://www.expedia.ca/Houston-Hotels-Omni-Houston-Hotel.h17746.Hotel-Information) Greater Uptown 9.0/10 Wonderful (1,001 reviews) CA $240 CA $284 total includes taxes & fees Feb 21 - Feb 22 [](https://www.expedia.ca/Houston-Hotels-Omni-Houston-Hotel.h17746.Hotel-Information) ![Lunch, dinner, brunch served; Italian cuisine ](https://images.trvl-media.com/lodging/1000000/30000/25000/24968/dbf192ed.jpg?impolicy=fcrop&w=357&h=201&p=1&q=medium) ![Exterior](https://images.trvl-media.com/lodging/1000000/30000/25000/24968/6ad32aff.jpg?impolicy=fcrop&w=357&h=201&p=1&q=medium) ![Premium bedding, in-room safe, laptop workspace, blackout drapes](https://images.trvl-media.com/lodging/1000000/30000/25000/24968/d9bd2c10.jpg?impolicy=fcrop&w=357&h=201&p=1&q=medium) ![Outdoor banquet area](https://images.trvl-media.com/lodging/1000000/30000/25000/24968/8d7abbc2.jpg?impolicy=fcrop&w=357&h=201&p=1&q=medium) ### C. Baldwin, Curio Collection by Hilton [](https://www.expedia.ca/Houston-Hotels-C-Baldwin.h24968.Hotel-Information) Downtown Houston 8.4/10 Very good (1,005 reviews) CA $210 CA $282 total includes taxes & fees Feb 22 - Feb 23 [](https://www.expedia.ca/Houston-Hotels-C-Baldwin.h24968.Hotel-Information) ![Serves dinner and happy hour](https://images.trvl-media.com/lodging/1000000/450000/440800/440776/917c8277.jpg?impolicy=fcrop&w=357&h=201&p=1&q=medium) ![Lobby](https://images.trvl-media.com/lodging/1000000/450000/440800/440776/63fd681c.jpg?impolicy=fcrop&w=357&h=201&p=1&q=medium) ![Outdoor pool, open 10:00 AM to 10:00 PM, sun loungers](https://images.trvl-media.com/lodging/1000000/450000/440800/440776/f2ae94c3.jpg?impolicy=fcrop&w=357&h=201&p=1&q=medium) ![Lobby](https://images.trvl-media.com/lodging/1000000/450000/440800/440776/6a6d4887.jpg?impolicy=fcrop&w=357&h=201&p=1&q=medium) ### The Chifley Houston, Tapestry Collection by Hilton [](https://www.expedia.ca/Houston-Hotels-Sheraton-Suites-Houston-Near-The-Galleria.h440776.Hotel-Information) The Galleria 9.2/10 Wonderful (1,249 reviews) CA $156 CA $183 total includes taxes & fees Feb 15 - Feb 16 [](https://www.expedia.ca/Houston-Hotels-Sheraton-Suites-Houston-Near-The-Galleria.h440776.Hotel-Information) ![Lobby](https://images.trvl-media.com/lodging/59000000/58990000/58985900/58985846/w3837h2505x3y0-1cfabad9.jpg?impolicy=fcrop&w=357&h=201&p=1&q=medium) ![Lobby](https://images.trvl-media.com/lodging/59000000/58990000/58985900/58985846/w3837h2340x3y0-41c8f6ac.jpg?impolicy=fcrop&w=357&h=201&p=1&q=medium) ![Premium bedding, minibar, in-room safe, individually decorated](https://images.trvl-media.com/lodging/59000000/58990000/58985900/58985846/1d5101c8.jpg?impolicy=fcrop&w=357&h=201&p=1&q=medium) ![Outdoor pool, sun loungers](https://images.trvl-media.com/lodging/59000000/58990000/58985900/58985846/w3837h2768x3y3-aed6fd99.jpg?impolicy=fcrop&w=357&h=201&p=1&q=medium) ### Blossom Hotel Houston, Curio Collection by Hilton [](https://www.expedia.ca/Houston-Hotels-Blossom-Hotel-Houston.h58985846.Hotel-Information) Texas Medical Center 9.0/10 Wonderful (3,713 reviews) CA $239 CA $280 total includes taxes & fees Feb 8 - Feb 9 [](https://www.expedia.ca/Houston-Hotels-Blossom-Hotel-Houston.h58985846.Hotel-Information) ![Terrace/patio](https://images.trvl-media.com/lodging/1000000/30000/25200/25188/77443f8e.jpg?impolicy=fcrop&w=357&h=201&p=1&q=medium) ![Lobby](https://images.trvl-media.com/lodging/1000000/30000/25200/25188/8964faa3.jpg?impolicy=fcrop&w=357&h=201&p=1&q=medium) ![Premium bedding, in-room safe, desk, laptop workspace](https://images.trvl-media.com/lodging/1000000/30000/25200/25188/e15c188d.jpg?impolicy=fcrop&w=357&h=201&p=1&q=medium) ![Outdoor pool, open 9 AM to 10 PM, free cabanas, sun loungers](https://images.trvl-media.com/lodging/1000000/30000/25200/25188/91b5a1be.jpg?impolicy=fcrop&w=357&h=201&p=1&q=medium) ### Hilton Houston Plaza/Medical Center [](https://www.expedia.ca/Houston-Hotels-Hilton-Houston-Plaza-Medical-Center.h25188.Hotel-Information) Texas Medical Center 8.4/10 Very good (1,830 reviews) CA $128 CA $152 total includes taxes & fees Feb 15 - Feb 16 [](https://www.expedia.ca/Houston-Hotels-Hilton-Houston-Plaza-Medical-Center.h25188.Hotel-Information) ![3 restaurants, breakfast served](https://images.trvl-media.com/lodging/1000000/10000/5900/5886/38290277.jpg?impolicy=fcrop&w=357&h=201&p=1&q=medium) ![Outdoor pool](https://images.trvl-media.com/lodging/1000000/10000/5900/5886/cb1de3f8.jpg?impolicy=fcrop&w=357&h=201&p=1&q=medium) ![Reception](https://images.trvl-media.com/lodging/1000000/10000/5900/5886/7374ed4d.jpg?impolicy=fcrop&w=357&h=201&p=1&q=medium) ![Premium bedding, down comforters, in-room safe, desk](https://images.trvl-media.com/lodging/1000000/10000/5900/5886/6d4b85c9.jpg?impolicy=fcrop&w=357&h=201&p=1&q=medium) ### Doubletree by Hilton Houston Hobby Airport [](https://www.expedia.ca/Houston-Hotels-Doubletree-By-Hilton-Houston-Hobby-Airport.h5886.Hotel-Information) Southeast Houston 8.8/10 Excellent (1,001 reviews) CA $145 CA $171 total includes taxes & fees Feb 15 - Feb 16 [](https://www.expedia.ca/Houston-Hotels-Doubletree-By-Hilton-Houston-Hobby-Airport.h5886.Hotel-Information) ![Exterior](https://images.trvl-media.com/lodging/1000000/20000/12100/12006/9e07eeec.jpg?impolicy=fcrop&w=357&h=201&p=1&q=medium) ![Reception](https://images.trvl-media.com/lodging/1000000/20000/12100/12006/dd968b5c.jpg?impolicy=fcrop&w=357&h=201&p=1&q=medium) ![Meeting facility](https://images.trvl-media.com/lodging/1000000/20000/12100/12006/80c59934.jpg?impolicy=fcrop&w=357&h=201&p=1&q=medium) ![Lobby lounge](https://images.trvl-media.com/lodging/1000000/20000/12100/12006/4a184dda.jpg?impolicy=fcrop&w=357&h=201&p=1&q=medium) ### Houston Marriott West Loop by The Galleria [](https://www.expedia.ca/Houston-Hotels-Houston-Marriott-West-Loop-By-The-Galleria.h12006.Hotel-Information) The Galleria 8.2/10 Very good (891 reviews) CA $140 CA $167 total includes taxes & fees Feb 13 - Feb 14 [](https://www.expedia.ca/Houston-Hotels-Houston-Marriott-West-Loop-By-The-Galleria.h12006.Hotel-Information) ![Outdoor pool, free cabanas, pool umbrellas](https://images.trvl-media.com/lodging/40000000/39620000/39618700/39618635/a994a387.jpg?impolicy=fcrop&w=357&h=201&p=1&q=medium) ![Exterior](https://images.trvl-media.com/lodging/40000000/39620000/39618700/39618635/9235e98a.jpg?impolicy=fcrop&w=357&h=201&p=1&q=medium) ![View from property](https://images.trvl-media.com/lodging/40000000/39620000/39618700/39618635/026cb2a8.jpg?impolicy=fcrop&w=357&h=201&p=1&q=medium) ![Lobby](https://images.trvl-media.com/lodging/40000000/39620000/39618700/39618635/c202dd0d.jpg?impolicy=fcrop&w=357&h=201&p=1&q=medium) ### The Westin Houston Medical Center/Museum District [](https://www.expedia.ca/Houston-Hotels-The-Westin-Houston-Medical-Center.h39618635.Hotel-Information) Texas Medical Center 9.2/10 Wonderful (1,089 reviews) CA $198 CA $247 total includes taxes & fees Feb 15 - Feb 16 [](https://www.expedia.ca/Houston-Hotels-The-Westin-Houston-Medical-Center.h39618635.Hotel-Information) ![Staircase](https://images.trvl-media.com/lodging/1000000/880000/878700/878652/5506d9bf.jpg?impolicy=fcrop&w=357&h=201&p=1&q=medium) ![Lobby sitting area](https://images.trvl-media.com/lodging/1000000/880000/878700/878652/b032cc4b.jpg?impolicy=fcrop&w=357&h=201&p=1&q=medium) ![Exterior](https://images.trvl-media.com/lodging/1000000/880000/878700/878652/8e6106b5.jpg?impolicy=fcrop&w=357&h=201&p=1&q=medium) ![Exterior](https://images.trvl-media.com/lodging/1000000/880000/878700/878652/9874e960.jpg?impolicy=fcrop&w=357&h=201&p=1&q=medium) ### The Royal Sonesta Houston Galleria [](https://www.expedia.ca/Houston-Hotels-Royal-Sonesta-Houston-Galleria.h878652.Hotel-Information) The Galleria 8.6/10 Excellent (1,602 reviews) - Luxury awaits at Houston Galleria hotel with plush pillowtop beds, Egyptian cotton sheets, and upscale shopping nearby. CA $173 CA $203 total includes taxes & fees Feb 22 - Feb 23 [](https://www.expedia.ca/Houston-Hotels-Royal-Sonesta-Houston-Galleria.h878652.Hotel-Information) Lowest nightly price found within the past 24 hours based on a 1 night stay for 2 adults. Prices and availability subject to change. Additional terms may apply. [View all properties](https://expedia.ca/Hotel-Search?startDate=2026-02-20&endDate=2026-02-21®ionId=6164045&adults=2&sort=LUXURY&star=40,50&openPlayBack=true) ## Top Museum District Hotel Reviews ![La Quinta Inn & Suites by Wyndham Houston Bush IAH South](https://images.trvl-media.com/lodging/1000000/170000/165600/165562/0afb5a51_y.jpg) ### La Quinta Inn & Suites by Wyndham Houston Bush IAH South 10/10 Excellent "Everything was clean and updated. The TV Was Annoying to work with." [](https://expedia.ca/Houston-Hotels-La-Quinta-Inn-Suites-By-Wyndham-Houston-Bush-IAH-South.h165562.Hotel-Information) ![Crowne Plaza Houston Med Ctr-Galleria Area by IHG](https://images.trvl-media.com/lodging/1000000/30000/28100/28060/38218191_y.jpg) ### Crowne Plaza Houston Med Ctr-Galleria Area by IHG 10/10 Excellent "Very convenient for our stay. My room was very clean. The staff was really nice as well." [](https://expedia.ca/Houston-Hotels-Crowne-Plaza-Houston-River-Oaks.h28060.Hotel-Information) ![The Royal Sonesta Houston Galleria](https://images.trvl-media.com/lodging/1000000/880000/878700/878652/9874e960_y.jpg) ### The Royal Sonesta Houston Galleria 10/10 Excellent "Quick Easy check in and Check out " [](https://expedia.ca/Houston-Hotels-Royal-Sonesta-Houston-Galleria.h878652.Hotel-Information) ![Hotel Zaza Houston Museum District](https://images.trvl-media.com/lodging/1000000/10000/3400/3306/47c5ade4_y.jpg) ### Hotel Zaza Houston Museum District 10/10 Excellent "Great location " [](https://expedia.ca/Houston-Hotels-Hotel-Zaza-Houston-Museum-District.h3306.Hotel-Information) ![Club Quarters Hotel Downtown, Houston](https://images.trvl-media.com/lodging/2000000/1160000/1157000/1156923/44a9a3fd_y.jpg) ### Club Quarters Hotel Downtown, Houston 10/10 Excellent "Clean, practical rooms. Quick check in and check out. " [](https://expedia.ca/Houston-Hotels-Club-Quarters-Hotel-In-Houston.h1156923.Hotel-Information) ![SpringHill Suites by Marriott Houston Intercontinental Arprt](https://images.trvl-media.com/lodging/3000000/2970000/2964300/2964240/69d373fc_y.jpg) ### SpringHill Suites by Marriott Houston Intercontinental Arprt 10/10 Excellent "Clean and spacious " [](https://expedia.ca/Houston-Hotels-SpringHill-Suites-By-Marriott-Houston-Intercontinental-Arprt.h2964240.Hotel-Information) ![Omni Houston Hotel](https://images.trvl-media.com/lodging/1000000/20000/17800/17746/37423ee4_y.jpg) ### Omni Houston Hotel 10/10 Excellent "Staff!!" [](https://expedia.ca/Houston-Hotels-Omni-Houston-Hotel.h17746.Hotel-Information) ![Magnolia Hotel Houston, A Tribute Portfolio Hotel](https://images.trvl-media.com/lodging/1000000/910000/907500/907459/0b2adb37_y.jpg) ### Magnolia Hotel Houston, A Tribute Portfolio Hotel 10/10 Excellent "Clean rooms and restrooms. Lovely decor. " [](https://expedia.ca/Houston-Hotels-Magnolia-Hotel-Houston.h907459.Hotel-Information) ![The Whitehall Houston](https://images.trvl-media.com/lodging/1000000/700000/693700/693655/f1d85056_y.jpg) ### The Whitehall Houston 10/10 Excellent "The Whitehall was an amazing place to stay. My daughter doesn't live far from the hotel, so it worked out perfectly for us when we needed to meet up. Above all, the staff from the front desk to the restaurant where absolutely amazing. Everyone was so friendly and went out of their way to make sure i had what i needed and was comfortable. Considering I was there the weekend of the snow storm and they were short staffed, I would have definitely understood if they didn't meet the mark, but they did. Great job to everyone!" [](https://expedia.ca/Houston-Hotels-The-Whitehall-Houston.h693655.Hotel-Information) ## Frequently asked questions ### Are you searching for a great accommodation for your luxury getaway to Museum District? ### What's there to see and do in Museum District? ### How can I get around Museum District? ## Explore a world of travel with Expedia - Lodging - Flights - Packages - Cars - Other - More ways to book - [2 Star Hotels in South Central Houston ](https://www.expedia.ca/2Star-South-Central-Houston-Houston-Hotels.s20-n553248635976476176-0.Travel-Guide-Filter-Hotels) - [Hotels near Children's Museum of Houston ](https://www.expedia.ca/Childrens-Museum-Of-Houston-Hotels.0-l6082211-0.Travel-Guide-Filter-Hotels) - [Hotels near Continental Club ](https://www.expedia.ca/Continental-Club-Hotels.0-l553248621533124447-0.Travel-Guide-Filter-Hotels) - [Downtown Houston Hotels ](https://www.expedia.ca/Downtown-Houston-Houston-Hotels.0-n800037-0.Travel-Guide-Filter-Hotels) - [B&B in Dryden/TMC Station ](https://www.expedia.ca/DrydenTMC-Station-Bed-And-Breakfast.d6211670-aaBedAndBreakfast.Travel-Guide-Accommodation) - 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