Title: Book the Best BUSINESS Hotels in Muscatine in 2026 | Expedia.ca [Muscatine Travel Guide](https://expedia.ca/Muscatine.dx8837)[Hotels in Muscatine](https://expedia.ca/Muscatine-Hotels.d8837.Travel-Guide-Hotels)[Vacation Rentals in Muscatine](https://expedia.ca/Muscatine-Vacation-Rentals.d8837.Travel-Guide-VacationRentals)[Muscatine Car Rentals](https://expedia.ca/Car-Rentals-In-Muscatine.d8837.Car-Rental-Guide)[Muscatine Vacation Packages](https://expedia.ca/Muscatine.d8837.Destination-Travel-Guides) ![Confluence of Mississippi and Wisconsin Rivers, Iowa](https://images.trvl-media.com/place/8837/02eff829-f20e-4c18-b722-c764489e3387.jpg?impolicy=fcrop&w=1200&h=500&q=medium) ![](https://images.trvl-media.com/place/8837/02eff829-f20e-4c18-b722-c764489e3387.jpg?impolicy=fcrop&w=1200&h=500&q=medium) - ![](https://a.travel-assets.com/travel-assets-manager/pictogram-bex/light__calendar_shield.svg) ### Change your mind Book hotels with free cancellation - ![](https://a.travel-assets.com/travel-assets-manager/pictogram-bex/light__deals.svg) ### Treat yourself Sign in to save 10% or more on thousands of hotels [Sign in](https://www.expedia.ca/login) - ![](https://a.travel-assets.com/travel-assets-manager/pictogram-bex/light__bed.svg) ### Be picky Search almost a million properties worldwide ## Check availability on Muscatine Business Hotels Tonight [Jan 16 - Jan 17](https://www.expedia.ca/Hotel-Search?regionId=8837&startDate=2026-01-16&endDate=2026-01-17&adults=2&rfrr=TG.LP.CheckPrices.Hotel&openPlayBack=true&travelerType=business_friendly) Tomorrow [Jan 17 - Jan 18](https://www.expedia.ca/Hotel-Search?regionId=8837&startDate=2026-01-17&endDate=2026-01-18&adults=2&rfrr=TG.LP.CheckPrices.Hotel&openPlayBack=true&travelerType=business_friendly) This weekend [Jan 16 - Jan 18](https://www.expedia.ca/Hotel-Search?regionId=8837&startDate=2026-01-16&endDate=2026-01-18&adults=2&rfrr=TG.LP.CheckPrices.Hotel&openPlayBack=true&travelerType=business_friendly) Next weekend [Jan 23 - Jan 25](https://www.expedia.ca/Hotel-Search?regionId=8837&startDate=2026-01-23&endDate=2026-01-25&adults=2&rfrr=TG.LP.CheckPrices.Hotel&openPlayBack=true&travelerType=business_friendly) ## Our top choices for Muscatine business-friendly hotels ![Lobby](https://images.trvl-media.com/lodging/1000000/980000/972800/972723/196e4344.jpg?impolicy=fcrop&w=357&h=201&p=1&q=medium) ![Indoor pool](https://images.trvl-media.com/lodging/1000000/980000/972800/972723/00dfe143.jpg?impolicy=fcrop&w=357&h=201&p=1&q=medium) ![Deluxe Studio Suite, 1 King Bed, Non Smoking](https://images.trvl-media.com/lodging/1000000/980000/972800/972723/074d8c6f.jpg?impolicy=fcrop&w=357&h=201&p=1&q=medium) ![Free daily buffet breakfast](https://images.trvl-media.com/lodging/1000000/980000/972800/972723/3762f8bd.jpg?impolicy=fcrop&w=357&h=201&p=1&q=medium) ### AmericInn by Wyndham Muscatine [](https://www.expedia.ca/Muscatine-Hotels-AmericInn-By-Wyndham-Muscatine.h972723.Hotel-Information) Muscatine 7.6/10 Good (426 reviews) "The room was pretty clean. Hair in the bathroom floor the whole time i was there though. The bed was a little too hard. The breakfast lacked options. All in all, a pretty good stay though." ![United States](https://a.travel-assets.com/egds/marks/flags/us.svg) Clell CA $112 CA $126 total includes taxes & fees Jan 25 - Jan 26 [](https://www.expedia.ca/Muscatine-Hotels-AmericInn-By-Wyndham-Muscatine.h972723.Hotel-Information) ![Reception](https://images.trvl-media.com/lodging/1000000/10000/1700/1657/61f61202.jpg?impolicy=fcrop&w=357&h=201&p=1&q=medium) ![Lobby sitting area](https://images.trvl-media.com/lodging/1000000/10000/1700/1657/8dbed251.jpg?impolicy=fcrop&w=357&h=201&p=1&q=medium) ![Business centre](https://images.trvl-media.com/lodging/1000000/10000/1700/1657/42f65219.jpg?impolicy=fcrop&w=357&h=201&p=1&q=medium) ![Indoor pool](https://images.trvl-media.com/lodging/1000000/10000/1700/1657/20bcf827.jpg?impolicy=fcrop&w=357&h=201&p=1&q=medium) ### Best Western Muscatine / Pearl City Hotel [](https://www.expedia.ca/Muscatine-Hotels-Best-Western-Pearl-City-Inn.h1657.Hotel-Information) Muscatine 8.6/10 Excellent (505 reviews) "Staff was very friendly and helpful. Free soup at night was very good and warming when temps got below 10\. Nice touch." ![United States](https://a.travel-assets.com/egds/marks/flags/us.svg) Andrew CA $124 CA $139 total includes taxes & fees Jan 18 - Jan 19 [](https://www.expedia.ca/Muscatine-Hotels-Best-Western-Pearl-City-Inn.h1657.Hotel-Information) ![48-inch flat-screen TV with cable channels, TV](https://images.trvl-media.com/lodging/22000000/21610000/21600200/21600105/b2245809.jpg?impolicy=fcrop&w=357&h=201&p=1&q=medium) ![Exterior](https://images.trvl-media.com/lodging/22000000/21610000/21600200/21600105/728aa272.jpg?impolicy=fcrop&w=357&h=201&p=1&q=medium) ![Lobby](https://images.trvl-media.com/lodging/22000000/21610000/21600200/21600105/bd843a4a.jpg?impolicy=fcrop&w=357&h=201&p=1&q=medium) ![Meeting facility](https://images.trvl-media.com/lodging/22000000/21610000/21600200/21600105/ca75ac05.jpg?impolicy=fcrop&w=357&h=201&p=1&q=medium) ### The Merrill Hotel, Muscatine, a Tribute Portfolio Hotel [](https://www.expedia.ca/Muscatine-Hotels-The-Merrill-Hotel.h21600105.Hotel-Information) Muscatine 9.6/10 Exceptional (280 reviews) "clean facility, very friendly and helpful staff" ![United States](https://a.travel-assets.com/egds/marks/flags/us.svg) Larry CA $235 CA $263 total includes taxes & fees Jan 23 - Jan 24 [](https://www.expedia.ca/Muscatine-Hotels-The-Merrill-Hotel.h21600105.Hotel-Information) ![Standard Room, 2 Queen Beds, Non Smoking](https://images.trvl-media.com/lodging/2000000/1690000/1683000/1682934/17d91b45.jpg?impolicy=fcrop&w=357&h=201&p=1&q=medium) ![Lobby](https://images.trvl-media.com/lodging/2000000/1690000/1683000/1682934/ecf2be7d.jpg?impolicy=fcrop&w=357&h=201&p=1&q=medium) ![Exterior](https://images.trvl-media.com/lodging/2000000/1690000/1683000/1682934/fb09d4cf.jpg?impolicy=fcrop&w=357&h=201&p=1&q=medium) ![Fitness facility](https://images.trvl-media.com/lodging/2000000/1690000/1683000/1682934/214ab24d.jpg?impolicy=fcrop&w=357&h=201&p=1&q=medium) ### Comfort Inn & Suites Davenport - Quad Cities [](https://www.expedia.ca/Davenport-Hotels-Comfort-Inn-Suites-Davenport-Quad-Cities.h1682934.Hotel-Information) Davenport 8.8/10 Excellent (1,002 reviews) "Clean room, friendly staff and very spacious room " ![United States](https://a.travel-assets.com/egds/marks/flags/us.svg) Lorenzo CA $99 CA $111 total includes taxes & fees Feb 8 - Feb 9 [](https://www.expedia.ca/Davenport-Hotels-Comfort-Inn-Suites-Davenport-Quad-Cities.h1682934.Hotel-Information) ![Free daily continental breakfast](https://images.trvl-media.com/lodging/104000000/103050000/103049000/103048959/9fa4c449.jpg?impolicy=fcrop&w=357&h=201&p=1&q=medium) ![Room, 1 Queen Bed, Accessible, Non Smoking (Mobility, Roll-in Shower)](https://images.trvl-media.com/lodging/104000000/103050000/103049000/103048959/c1d34f13.jpg?impolicy=fcrop&w=357&h=201&p=1&q=medium) ![Fitness facility](https://images.trvl-media.com/lodging/104000000/103050000/103049000/103048959/feb437ae.jpg?impolicy=fcrop&w=357&h=201&p=1&q=medium) ![Suite, 1 Bedroom, Non Smoking (1 King Bed)](https://images.trvl-media.com/lodging/104000000/103050000/103049000/103048959/3940fc46.jpg?impolicy=fcrop&w=357&h=201&p=1&q=medium) ### Days Inn By Wyndham Davenport [](https://www.expedia.ca/Davenport-Hotels-Days-Inn-By-Wyndham-Davenport.h103048959.Hotel-Information) Davenport 8.0/10 Very good (390 reviews) "Overall was a nice place for the price " ![United States](https://a.travel-assets.com/egds/marks/flags/us.svg) kevin CA $74 CA $83 total includes taxes & fees Jan 18 - Jan 19 [](https://www.expedia.ca/Davenport-Hotels-Days-Inn-By-Wyndham-Davenport.h103048959.Hotel-Information) ![Exterior](https://images.trvl-media.com/lodging/8000000/7640000/7639800/7639711/1e607b2a.jpg?impolicy=fcrop&w=357&h=201&p=1&q=medium) ![Point of interest](https://images.trvl-media.com/lodging/8000000/7640000/7639800/7639711/708ad3dd.jpg?impolicy=fcrop&w=357&h=201&p=1&q=medium) ![Point of interest](https://images.trvl-media.com/lodging/8000000/7640000/7639800/7639711/e479c270.jpg?impolicy=fcrop&w=357&h=201&p=1&q=medium) ![Lobby sitting area](https://images.trvl-media.com/lodging/8000000/7640000/7639800/7639711/b77e9623.jpg?impolicy=fcrop&w=357&h=201&p=1&q=medium) ### Holiday Inn Express Moline - Quad Cities Area by IHG [](https://www.expedia.ca/Moline-Hotels-Holiday-Inn-Express-Moline-Quad-Cities-Area.h7639711.Hotel-Information) Moline 9.4/10 Exceptional (717 reviews) "Clean room, FANTASTIC breakfast, friendly and fast-acting staff" ![United States](https://a.travel-assets.com/egds/marks/flags/us.svg) Nick CA $132 CA $149 total includes taxes & fees Feb 1 - Feb 2 [](https://www.expedia.ca/Moline-Hotels-Holiday-Inn-Express-Moline-Quad-Cities-Area.h7639711.Hotel-Information) ![Lobby](https://images.trvl-media.com/lodging/1000000/30000/28200/28199/1a69283e.jpg?impolicy=fcrop&w=357&h=201&p=1&q=medium) ![Lobby](https://images.trvl-media.com/lodging/1000000/30000/28200/28199/w3839h2586x0y0-7ce07d45.jpg?impolicy=fcrop&w=357&h=201&p=1&q=medium) ![Lobby](https://images.trvl-media.com/lodging/1000000/30000/28200/28199/70229249.jpg?impolicy=fcrop&w=357&h=201&p=1&q=medium) ![Lobby](https://images.trvl-media.com/lodging/1000000/30000/28200/28199/5792fea3.jpg?impolicy=fcrop&w=357&h=201&p=1&q=medium) ### DoubleTree by Hilton Davenport [](https://www.expedia.ca/Davenport-Hotels-DoubleTree-By-Hilton-Davenport.h28199.Hotel-Information) Downtown Davenport 7.6/10 Good (1,001 reviews) "Room was great, staff was exceptionally nice. " ![United States](https://a.travel-assets.com/egds/marks/flags/us.svg) Brianne CA $96 CA $107 total includes taxes & fees Feb 1 - Feb 2 [](https://www.expedia.ca/Davenport-Hotels-DoubleTree-By-Hilton-Davenport.h28199.Hotel-Information) ![Indoor pool, open 8:00 AM to 10:00 PM, sun loungers](https://images.trvl-media.com/lodging/1000000/10000/8300/8203/5d4f5e22.jpg?impolicy=fcrop&w=357&h=201&p=1&q=medium) ![Free daily buffet breakfast](https://images.trvl-media.com/lodging/1000000/10000/8300/8203/c9a680f1.jpg?impolicy=fcrop&w=357&h=201&p=1&q=medium) ![Property amenity](https://images.trvl-media.com/lodging/1000000/10000/8300/8203/8bde8192.jpg?impolicy=fcrop&w=357&h=201&p=1&q=medium) ![Property amenity](https://images.trvl-media.com/lodging/1000000/10000/8300/8203/daa71d51.jpg?impolicy=fcrop&w=357&h=201&p=1&q=medium) ### Best Western Plus Steeplegate Inn [](https://www.expedia.ca/Davenport-Hotels-Best-Western-Plus-Steeplegate-Inn.h8203.Hotel-Information) Davenport 8.2/10 Very good (1,001 reviews) "The staff was very friendly and greeted us every time we saw them. My room was spotless, the beds, pillows, indoor pool and housekeeping staff were wonderful! We had a 4 day stay here to visit family and will definitely stay here again! And yes, they are pet friendly! Thank you!" ![United States](https://a.travel-assets.com/egds/marks/flags/us.svg) Linda CA $100 CA $112 total includes taxes & fees Jan 25 - Jan 26 [](https://www.expedia.ca/Davenport-Hotels-Best-Western-Plus-Steeplegate-Inn.h8203.Hotel-Information) ![Interior entrance](https://images.trvl-media.com/lodging/20000000/19180000/19176200/19176200/6dc3932c.jpg?impolicy=fcrop&w=357&h=201&p=1&q=medium) ![Premium bedding, in-room safe, desk, iron/ironing board](https://images.trvl-media.com/lodging/20000000/19180000/19176200/19176200/4b609ee3.jpg?impolicy=fcrop&w=357&h=201&p=1&q=medium) ![Casino](https://images.trvl-media.com/lodging/20000000/19180000/19176200/19176200/3414696e.jpg?impolicy=fcrop&w=357&h=201&p=1&q=medium) ![Casino](https://images.trvl-media.com/lodging/20000000/19180000/19176200/19176200/e42f29d1.jpg?impolicy=fcrop&w=357&h=201&p=1&q=medium) ### Rhythm City Casino Resort [](https://www.expedia.ca/Davenport-Hotels-Rhythm-City-Casino-And-Resort.h19176200.Hotel-Information) Davenport 9.2/10 Wonderful (1,001 reviews) "great rooms very comfortable stay " ![United States](https://a.travel-assets.com/egds/marks/flags/us.svg) joel [](https://www.expedia.ca/Davenport-Hotels-Rhythm-City-Casino-And-Resort.h19176200.Hotel-Information) ![Lobby](https://images.trvl-media.com/lodging/1000000/900000/890800/890745/e6ba9043.jpg?impolicy=fcrop&w=357&h=201&p=1&q=medium) ![Lobby](https://images.trvl-media.com/lodging/1000000/900000/890800/890745/e44b240f.jpg?impolicy=fcrop&w=357&h=201&p=1&q=medium) ![In-room safe, desk, iron/ironing board, free WiFi](https://images.trvl-media.com/lodging/1000000/900000/890800/890745/e6b6fb58.jpg?impolicy=fcrop&w=357&h=201&p=1&q=medium) ![Indoor pool](https://images.trvl-media.com/lodging/1000000/900000/890800/890745/1beef060.jpg?impolicy=fcrop&w=357&h=201&p=1&q=medium) ### Sleep Inn & Suites Davenport - Quad Cities [](https://www.expedia.ca/Davenport-Hotels-Sleep-Inn-Suites-Davenport-Quad-Cities.h890745.Hotel-Information) Davenport 8.2/10 Very good (968 reviews) "I would definitely stay again " ![United States](https://a.travel-assets.com/egds/marks/flags/us.svg) Tanja CA $90 CA $101 total includes taxes & fees Jan 25 - Jan 26 [](https://www.expedia.ca/Davenport-Hotels-Sleep-Inn-Suites-Davenport-Quad-Cities.h890745.Hotel-Information) Lowest nightly price found within the past 24 hours based on a 1 night stay for 2 adults. Prices and availability subject to change. Additional terms may apply. [View all properties](https://expedia.ca/Hotel-Search?startDate=2026-01-30&endDate=2026-01-31®ionId=8837&adults=2&travelerType=business_friendly&sort=RECOMMENDED&openPlayBack=true) ## Top Muscatine Hotel Reviews ![DoubleTree by Hilton Davenport](https://images.trvl-media.com/lodging/1000000/30000/28200/28199/w3839h2586x0y0-7ce07d45_y.jpg) ### DoubleTree by Hilton Davenport 10/10 Excellent "Clean room, extremely friendly staff, and loved that there was a skywalk to our venue!" [](https://expedia.ca/Davenport-Hotels-DoubleTree-By-Hilton-Davenport.h28199.Hotel-Information) ![Isle Casino Hotel - Bettendorf](https://images.trvl-media.com/lodging/2000000/1780000/1771100/1771006/dcb75544_y.jpg) ### Isle Casino Hotel - Bettendorf 10/10 Excellent "Loved the room and the staff was friendly." [](https://expedia.ca/Bettendorf-Hotels-Isle-Casino-Hotel-Bettendorf.h1771006.Hotel-Information) ![Wyndham Moline on John Deere Commons](https://images.trvl-media.com/lodging/1000000/50000/43400/43329/bc3dbe4c_y.jpg) ### Wyndham Moline on John Deere Commons 10/10 Excellent "Rooms are always great " [](https://expedia.ca/Moline-Hotels-Radisson-On-John-Deere-Commons-Moline.h43329.Hotel-Information) ![Hotel Blackhawk, Autograph Collection](https://images.trvl-media.com/lodging/1000000/30000/26400/26385/1d458afa_y.jpg) ### Hotel Blackhawk, Autograph Collection 10/10 Excellent "Amazing hotel! " [](https://expedia.ca/Davenport-Hotels-Hotel-Blackhawk.h26385.Hotel-Information) ![Stoney Creek Hotel Quad Cities - Moline](https://images.trvl-media.com/lodging/2000000/1370000/1364000/1363998/14573bee_y.jpg) ### Stoney Creek Hotel Quad Cities - Moline 10/10 Excellent "They needed help making breakfast. When we got down there, almost everything was out and some things were totally out. It was pretty crowded with families so I don't think the cook could keep up fast enough. We had to wait for some time for some new stuff to come out." [](https://expedia.ca/Moline-Hotels-Stoney-Creek-Hotel-Quad-Cities-Moline.h1363998.Hotel-Information) ![Sleep Inn & Suites Davenport - Quad Cities](https://images.trvl-media.com/lodging/1000000/900000/890800/890745/e44b240f_y.jpg) ### Sleep Inn & Suites Davenport - Quad Cities 10/10 Excellent "Breakfast items seemed fresh. " [](https://expedia.ca/Davenport-Hotels-Sleep-Inn-Suites-Davenport-Quad-Cities.h890745.Hotel-Information) ![AmericInn by Wyndham Muscatine](https://images.trvl-media.com/lodging/1000000/980000/972800/972723/00dfe143_y.jpg) ### AmericInn by Wyndham Muscatine 10/10 Excellent "Staff members were very kind and accommodating, hotel was noticeably cleaner than our previous visit- updates to the room, etc were nice and appreciated!" [](https://expedia.ca/Muscatine-Hotels-AmericInn-By-Wyndham-Muscatine.h972723.Hotel-Information) ![Best Western Plus Steeplegate Inn](https://images.trvl-media.com/lodging/1000000/10000/8300/8203/8bde8192_y.jpg) ### Best Western Plus Steeplegate Inn 10/10 Excellent "The employees were very friendly. My friend and I spent New Year's Eve at this hotel in Davenport. The staff on the night and the morning were all very friendly, and the breakfast was amazing. The overall atmosphere was calm and cozy, and the price was reasonable.We even stayed longer after checking out to play pool in the lobby. Oh, and coffee was available everywhere: in the lobby, in the room, and in the kitchen." [](https://expedia.ca/Davenport-Hotels-Best-Western-Plus-Steeplegate-Inn.h8203.Hotel-Information) ![Country Inn & Suites by Radisson, Moline Airport, IL](https://images.trvl-media.com/lodging/1000000/450000/445600/445572/f9a46e6b_y.jpg) ### Country Inn & Suites by Radisson, Moline Airport, IL 10/10 Excellent " Spotless room and the front desk was very helpful and polite." [](https://expedia.ca/Moline-Hotels-Country-Inn-Suites-By-Radisson.h445572.Hotel-Information) ## Frequently asked questions ### How much do business-friendly hotels in Muscatine cost? ### What are the best business-friendly hotels in Muscatine? ### How many business-friendly hotels are there in Muscatine? ### What are the best cheap business-friendly hotels in Muscatine? ### Are there any family-friendly hotels in Muscatine that are also business friendly? ### Why book your business-friendly hotel in Muscatine with Expedia? ### How can I find cheap business-friendly hotels in Muscatine? ### What is there to do in Muscatine near my business-friendly hotel? ## Explore a world of travel with Expedia - Lodging - Flights - Packages - Cars - Vacation Rental - More ways to book - [4 Star Hotels in Oakville ](https://www.expedia.ca/4Star-Oakville-Hotels.s40-0-d553248634983358116.Travel-Guide-Filter-Hotels) - [Atalissa Hotels ](https://www.expedia.ca/Atalissa-Hotels.d553248634983229179.Travel-Guide-Hotels) - 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