Title: Hotels by Wyndham Hotels in Murphysboro | Expedia.ca [Murphysboro Travel Guide](https://expedia.ca/Murphysboro.dx55857)[Hotels in Murphysboro](https://expedia.ca/Murphysboro-Hotels.d55857.Travel-Guide-Hotels)[Vacation Rentals in Murphysboro](https://expedia.ca/Murphysboro-Vacation-Rentals.d55857.Travel-Guide-VacationRentals)[Flights to Murphysboro](https://expedia.ca/Cheap-Flights-To-Murphysboro.d55857.Travel-Guide-Flights)[Murphysboro Car Rentals](https://expedia.ca/Car-Rentals-In-Murphysboro.d55857.Car-Rental-Guide)[Murphysboro Vacation Packages](https://expedia.ca/Murphysboro.d55857.Destination-Travel-Guides) ![](https://a.travel-assets.com/findyours-php/viewfinder/images/res70/208000/208702-Southern-Illinois.jpg?impolicy=fcrop&w=1200&h=500&q=medium) # Find Hotels by Wyndham Hotels in Murphysboro ![](https://a.travel-assets.com/travel-assets-manager/pictogram-bex/light__calendar_shield.svg) ### Change your mind Book hotels with free cancellation ![](https://a.travel-assets.com/travel-assets-manager/pictogram-bex/light__deals.svg) ### Treat yourself Sign in to save 10% or more on thousands of hotels [Sign in](https://www.expedia.ca/login) ![](https://a.travel-assets.com/travel-assets-manager/pictogram-bex/light__bed.svg) ### Be picky Search almost a million properties worldwide ## Check prices for these dates Tonight [Oct 25 - Oct 26](https://www.expedia.ca/Hotel-Search?regionId=55857&startDate=2025-10-25&endDate=2025-10-26&adults=2&rfrr=TG.LP.CheckPrices.Hotel&openPlayBack=true) Tomorrow [Oct 26 - Oct 27](https://www.expedia.ca/Hotel-Search?regionId=55857&startDate=2025-10-26&endDate=2025-10-27&adults=2&rfrr=TG.LP.CheckPrices.Hotel&openPlayBack=true) Next weekend [Oct 31 - Nov 2](https://www.expedia.ca/Hotel-Search?regionId=55857&startDate=2025-10-31&endDate=2025-11-02&adults=2&rfrr=TG.LP.CheckPrices.Hotel&openPlayBack=true) In two weeks [Nov 7 - Nov 9](https://www.expedia.ca/Hotel-Search?regionId=55857&startDate=2025-11-07&endDate=2025-11-09&adults=2&rfrr=TG.LP.CheckPrices.Hotel&openPlayBack=true) ## Top Murphysboro Wyndham Hotels Hotels ![](https://a.travel-assets.com/pricing-claim/sparkle_dark.svg) Save an average of 15% on thousands of hotels when you're signed in [Sign in](https://expedia.ca/user/signin?ckoflag=0&uurl=e3id%3Dredr%26rurl%3D%2FMurphysboro-Hotels-Wyndham-Hotels.0-0-d55857--bWyndhamHotels.Travel-Guide-Filter-Hotels)[Sign up, it's free](https://expedia.ca/signup?enable_registration=true&+=&uurl=e3id%3Dredr%26rurl%3D%2FMurphysboro-Hotels-Wyndham-Hotels.0-0-d55857--bWyndhamHotels.Travel-Guide-Filter-Hotels) ## Top Murphysboro Hotel Reviews ![Comfort Inn & Suites Marion I-57](//images.trvl-media.com/lodging/6000000/5160000/5156200/5156103/28688440_y.jpg) ### Comfort Inn & Suites Marion I-57 10/10 Excellent "Solid place in good area friendly staff " [](https://expedia.ca/Carbondale-Hotels-Comfort-Inn-Suites-Marion-I-57.h5156103.Hotel-Information) ![Holiday Inn Carbondale-Conference Center by IHG](//images.trvl-media.com/lodging/2000000/1490000/1489300/1489254/c0186ee3_y.jpg) ### Holiday Inn Carbondale-Conference Center by IHG 10/10 Excellent "Front desk was so kind and welcoming. The room was awesome and super comfy. Breakfast just had fruit and boxed items, warm foods would be a nice touch with all the nice renovations. Would stay here again." [](https://expedia.ca/Carbondale-Hotels-Holiday-Inn-Carbondale-Conference-Center.h1489254.Hotel-Information) ![Super 8 by Wyndham Carbondale](//images.trvl-media.com/lodging/1000000/440000/439700/439693/8adbc8b5_y.jpg) ### Super 8 by Wyndham Carbondale 10/10 Excellent "Clean room. Good location. Staff was warm and welcoming." [](https://expedia.ca/Carbondale-Hotels-Super-8-By-Wyndham-Carbondale.h439693.Hotel-Information) ![Best Western Saluki Inn](//images.trvl-media.com/lodging/1000000/120000/119200/119178/3da90d9b_y.jpg) ### Best Western Saluki Inn 10/10 Excellent "Our room was clean and pleasant, our stay was fantastic for as short notice as we had to get this room. The staff also helped me print something out that I needed for an event I was in town for, as I'd printed too small and they were so gracious to assist. Thank you all again for our stay, we'll see you next time we are in town to visit family. " [](https://expedia.ca/Carbondale-Hotels-Best-Western-Saluki-Inn.h119178.Hotel-Information) ![Best Western Marion Hotel](//images.trvl-media.com/lodging/1000000/100000/98000/97975/86964c5d_y.jpg) ### Best Western Marion Hotel 10/10 Excellent "Our check in was smooth, good restaurant recommendation, bed comfortable and very clean. " [](https://expedia.ca/Carbondale-Hotels-Best-Western-Marion-Hotel.h97975.Hotel-Information) ![Comfort Inn & Suites Carbondale University Area](//images.trvl-media.com/lodging/3000000/2970000/2967300/2967285/56170235_y.jpg) ### Comfort Inn & Suites Carbondale University Area 10/10 Excellent "Everything was nice breakfast was gros" [](https://expedia.ca/Carbondale-Hotels-Comfort-Inn-Suites.h2967285.Hotel-Information) ![Country Inn & Suites by Radisson, Marion, IL](//images.trvl-media.com/lodging/3000000/2460000/2457400/2457332/6bf09f9e_y.jpg) ### Country Inn & Suites by Radisson, Marion, IL 10/10 Excellent "Very safe area" [](https://expedia.ca/Carbondale-Hotels-Country-Inn-Suites-By-Radisson.h2457332.Hotel-Information) ![Holiday Inn Express & Suites Murphysboro - Carbondale by IHG](//images.trvl-media.com/lodging/64000000/63310000/63308800/63308723/2785ae14_y.jpg) ### Holiday Inn Express & Suites Murphysboro - Carbondale by IHG 10/10 Excellent "We enjoyed our two night stay. Even being four years old the property appeared new. Our 4th floor room was clean and comfortable. The breakfast was good. The pancake machine worked very well & fast. Their coffee machine ground the coffee beans and brewed fresh coffee with every cup. We will gladly return to this hotel when we are in the area." [](https://expedia.ca/Carbondale-Hotels-Holiday-Inn-Express-Suites-Murphysboro-Carbondale.h63308723.Hotel-Information) ![Baymont by Wyndham Marion](//images.trvl-media.com/lodging/1000000/20000/19300/19275/7eb84743_y.jpg) ### Baymont by Wyndham Marion 10/10 Excellent "Breakfast was ok, mostly cereal, breads and pastry choices, as well as microwavable sausage biscuits. Juice machine out of order, but coffee was excellent. But didn't choose this hotel for breakfast. Room for not disappoint, king bed excellent, quiet ac, and clean room. One small nitpick, the lighting was a bit too dark for us. But overall, a nice clean quiet and comfortable overnight stay for us." 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