Title: Book the Best Murex Lakes Adults Only Resorts & Hotels in 2025 from CA $105 | Expedia.ca [Vacation Rentals in Sanibel](https://expedia.ca/Sanibel-Vacation-Rentals.d9791.Travel-Guide-VacationRentals)[Flights to Sanibel](https://expedia.ca/Cheap-Flights-To-Sanibel.d9791.Travel-Guide-Flights)[Things to do in Sanibel](https://expedia.ca/Things-To-Do-In-Sanibel.d9791.Travel-Guide-Activities)[Murex Lakes Car Rentals](https://expedia.ca/Car-Rentals-In-Murex-Lakes.d553248635976468770.Car-Rental-Guide)[Murex Lakes Vacations](https://expedia.ca/Murex-Lakes.d553248635976468770.Destination-Travel-Guides) ![Default HTG hotel image](https://a.travel-assets.com/travel-assets-manager/bex-affinities/adultsonly.jpg?impolicy=fcrop&w=1200&h=500&q=medium) # Find Adults Only Resorts & Hotels in Murex Lakes, FL from CA $105 - ![](https://a.travel-assets.com/travel-assets-manager/pictogram-bex/light__calendar_shield.svg) ### Change your mind Book hotels with free cancellation - ![](https://a.travel-assets.com/travel-assets-manager/pictogram-bex/light__deals.svg) ### Treat yourself Sign in to save 10% or more on thousands of hotels [Sign in](https://www.expedia.ca/login) - ![](https://a.travel-assets.com/travel-assets-manager/pictogram-bex/light__bed.svg) ### Be picky Search almost a million properties worldwide ## Check availability on Murex Lakes Adults Only Resorts & Hotels Tonight [Nov 21 - Nov 22](https://www.expedia.ca/Hotel-Search?regionId=553248635976468770&startDate=2025-11-21&endDate=2025-11-22&adults=2&rfrr=TG.LP.CheckPrices.Hotel&openPlayBack=true&travelerType=adults_only) Tomorrow [Nov 22 - Nov 23](https://www.expedia.ca/Hotel-Search?regionId=553248635976468770&startDate=2025-11-22&endDate=2025-11-23&adults=2&rfrr=TG.LP.CheckPrices.Hotel&openPlayBack=true&travelerType=adults_only) This weekend [Nov 21 - Nov 23](https://www.expedia.ca/Hotel-Search?regionId=553248635976468770&startDate=2025-11-21&endDate=2025-11-23&adults=2&rfrr=TG.LP.CheckPrices.Hotel&openPlayBack=true&travelerType=adults_only) Next weekend [Nov 28 - Nov 30](https://www.expedia.ca/Hotel-Search?regionId=553248635976468770&startDate=2025-11-28&endDate=2025-11-30&adults=2&rfrr=TG.LP.CheckPrices.Hotel&openPlayBack=true&travelerType=adults_only) ## Top Murex Lakes Adults Only Resorts & Hotels No exact matches found, but these alternatives could be just right ## Recommended hotels in Murex Lakes ![Exterior](https://images.trvl-media.com/lodging/50000000/49160000/49152700/49152700/a69cd385.jpg?impolicy=fcrop&w=357&h=201&p=1&q=medium) ![Reception](https://images.trvl-media.com/lodging/50000000/49160000/49152700/49152700/088bfb58.jpg?impolicy=fcrop&w=357&h=201&p=1&q=medium) ![Property amenity](https://images.trvl-media.com/lodging/50000000/49160000/49152700/49152700/798de6a2.jpg?impolicy=fcrop&w=357&h=201&p=1&q=medium) ![1 bedroom, hypo-allergenic bedding, pillowtop beds, in-room safe](https://images.trvl-media.com/lodging/50000000/49160000/49152700/49152700/fe3aa003.jpg?impolicy=fcrop&w=357&h=201&p=1&q=medium) ### Holiday Inn Express & Suites Ft Myers Beach-Sanibel Gateway by IHG Fort Myers Beach 9.4/10 Exceptional (1010) "Excellent room and price! Breakfast was great. Holiday Inn Express is doing everything right for a comfortable stay." ![United States](https://a.travel-assets.com/egds/marks/flags/us.svg) Denise CA $111 CA $124 total includes taxes & fees Nov 23 - Nov 24 [](https://www.expedia.ca/Fort-Myers-Hotels-Holiday-Inn-Express-Suites-Ft-Myers-Beach-Sanibel-Gateway.h49152700.Hotel-Information) ![Suite with King Bed, Beachfront, Balcony | Terrace/patio](https://images.trvl-media.com/lodging/1000000/440000/438800/438796/b5b17142.jpg?impolicy=fcrop&w=357&h=201&p=1&q=medium) ![Suite with Two Doubles, Beachfront, Balcony](https://images.trvl-media.com/lodging/1000000/440000/438800/438796/2e8856cf.jpg?impolicy=fcrop&w=357&h=201&p=1&q=medium) ![Standard Beachfront, Balcony, Two Doubles](https://images.trvl-media.com/lodging/1000000/440000/438800/438796/de245384.jpg?impolicy=fcrop&w=357&h=201&p=1&q=medium) ![Sundeck](https://images.trvl-media.com/lodging/1000000/440000/438800/438796/1808ce0e.jpg?impolicy=fcrop&w=357&h=201&p=1&q=medium) ### Lani Kai Beachfront Resort Fort Myers Beach 8.8/10 Excellent (1023) " Nice place to stay " ![United States](https://a.travel-assets.com/egds/marks/flags/us.svg) Timothy CA $255 CA $316 total includes taxes & fees Nov 23 - Nov 24 [](https://www.expedia.ca/Fort-Myers-Hotels-Lani-Kai-Beachfront-Resort.h438796.Hotel-Information) ![Bar (on property)](https://images.trvl-media.com/lodging/3000000/2670000/2665100/2665085/fc463bf9.jpg?impolicy=fcrop&w=357&h=201&p=1&q=medium) ![Premium bedding, iron/ironing board, free WiFi, bed sheets](https://images.trvl-media.com/lodging/3000000/2670000/2665100/2665085/2a7931b8.jpg?impolicy=fcrop&w=357&h=201&p=1&q=medium) ![Outdoor pool](https://images.trvl-media.com/lodging/3000000/2670000/2665100/2665085/e46c7f87.jpg?impolicy=fcrop&w=357&h=201&p=1&q=medium) ![Fishing](https://images.trvl-media.com/lodging/3000000/2670000/2665100/2665085/6e3a1f40.jpg?impolicy=fcrop&w=357&h=201&p=1&q=medium) ### Matanzas Inn Bayside Resort and Marina Fort Myers Beach 9.2/10 Wonderful (1004) "Clean room, great staff, pizza at the bar was amazing " ![United States](https://a.travel-assets.com/egds/marks/flags/us.svg) Lori [](https://www.expedia.ca/Fort-Myers-Hotels-Matanzas-Inn-Bayside-Resort-And-Marina.h2665085.Hotel-Information) ![Exterior](https://images.trvl-media.com/lodging/104000000/103190000/103186900/103186827/9de7241c.jpg?impolicy=fcrop&w=357&h=201&p=1&q=medium) ![Lobby](https://images.trvl-media.com/lodging/104000000/103190000/103186900/103186827/0afa75e7.jpg?impolicy=fcrop&w=357&h=201&p=1&q=medium) ![Lobby sitting area](https://images.trvl-media.com/lodging/104000000/103190000/103186900/103186827/35ad9ea5.jpg?impolicy=fcrop&w=357&h=201&p=1&q=medium) ![Queen Suite w/ Dishwasher (Dishes/Cookware Included) Accessible Roll-in Shower | Private kitchenette](https://images.trvl-media.com/lodging/104000000/103190000/103186900/103186827/ba927dda.jpg?impolicy=fcrop&w=357&h=201&p=1&q=medium) ### Woodspring Suites Fort Myers - Cape Coral Fort Myers 7.2/10 Good (141) "For the price, the sheets were clean. " ![United States](https://a.travel-assets.com/egds/marks/flags/us.svg) Dairon CA $97 CA $108 total includes taxes & fees Nov 26 - Nov 27 [](https://www.expedia.ca/Fort-Myers-Hotels-Woodspring-Suites-Fort-Myers-Cape-Coral.h103186827.Hotel-Information) ![Exterior](https://images.trvl-media.com/lodging/96000000/95130000/95127000/95126992/w3998h2821x0y0-a77e6574.jpg?impolicy=fcrop&w=357&h=201&p=1&q=medium) ![Terrace/patio](https://images.trvl-media.com/lodging/96000000/95130000/95127000/95126992/1051a5d9.jpg?impolicy=fcrop&w=357&h=201&p=1&q=medium) ![Premium bedding, in-room safe, desk, iron/ironing board](https://images.trvl-media.com/lodging/96000000/95130000/95127000/95126992/b4312f5c.jpg?impolicy=fcrop&w=357&h=201&p=1&q=medium) ![4 restaurants, breakfast served](https://images.trvl-media.com/lodging/96000000/95130000/95127000/95126992/abf6da91.jpg?impolicy=fcrop&w=357&h=201&p=1&q=medium) ### Margaritaville Beach Resort Fort Myers Fort Myers Beach 9.0/10 Wonderful (1648) "Very nice and clean resort! " ![United States](https://a.travel-assets.com/egds/marks/flags/us.svg) Stephanie CA $203 CA $297 total includes taxes & fees Dec 9 - Dec 10 [](https://www.expedia.ca/Fort-Myers-Beach-Hotels-Margaritaville-Beach-Resort-Fort-Myers.h95126992.Hotel-Information) ![Lobby lounge](https://images.trvl-media.com/lodging/1000000/130000/129300/129295/81b75b6a.jpg?impolicy=fcrop&w=357&h=201&p=1&q=medium) ![Outdoor pool, pool umbrellas, sun loungers](https://images.trvl-media.com/lodging/1000000/130000/129300/129295/54b01dcc.jpg?impolicy=fcrop&w=357&h=201&p=1&q=medium) ![Property entrance](https://images.trvl-media.com/lodging/1000000/130000/129300/129295/1a5de0b7.jpg?impolicy=fcrop&w=357&h=201&p=1&q=medium) ![Room, 1 King Bed, Non Smoking](https://images.trvl-media.com/lodging/1000000/130000/129300/129295/476eda2a.jpg?impolicy=fcrop&w=357&h=201&p=1&q=medium) ### Fairfield Inn & Suites by Marriott Ft. Myers/Cape Coral Villas 8.6/10 Excellent (776) "Clean room and very nice staff " ![United States](https://a.travel-assets.com/egds/marks/flags/us.svg) Michael CA $100 CA $111 total includes taxes & fees Nov 30 - Dec 1 [](https://www.expedia.ca/Fort-Myers-Hotels-Fairfield-Inn-Suites-By-Marriott-Ft-MyersCape-Coral.h129295.Hotel-Information) ![Exterior](https://images.trvl-media.com/lodging/27000000/26920000/26914900/26914841/3e7873b7.jpg?impolicy=fcrop&w=357&h=201&p=1&q=medium) ![Point of interest](https://images.trvl-media.com/lodging/27000000/26920000/26914900/26914841/9079647e.jpg?impolicy=fcrop&w=357&h=201&p=1&q=medium) ![Exterior](https://images.trvl-media.com/lodging/27000000/26920000/26914900/26914841/56a5c955.jpg?impolicy=fcrop&w=357&h=201&p=1&q=medium) ![Deluxe King Studio Waterfront](https://images.trvl-media.com/lodging/27000000/26920000/26914900/26914841/cf6a8265.jpg?impolicy=fcrop&w=357&h=201&p=1&q=medium) ### Latitude 26 Waterfront Boutique Resort - Bonita Springs Bonita Springs 8.8/10 Excellent (684) "We enjoyed our stay. The accommodations were great!" ![United States](https://a.travel-assets.com/egds/marks/flags/us.svg) Conny CA $139 CA $159 total includes taxes & fees Nov 23 - Nov 24 [](https://www.expedia.ca/Naples-Hotels-Latitude-26-Waterfront-Boutique-Resort.h26914841.Hotel-Information) ![Outdoor pool](https://images.trvl-media.com/lodging/3000000/2630000/2625800/2625745/83cb6bb9.jpg?impolicy=fcrop&w=357&h=201&p=1&q=medium) ![Reception](https://images.trvl-media.com/lodging/3000000/2630000/2625800/2625745/5f2e6784.jpg?impolicy=fcrop&w=357&h=201&p=1&q=medium) ![Lobby](https://images.trvl-media.com/lodging/3000000/2630000/2625800/2625745/432e75cc.jpg?impolicy=fcrop&w=357&h=201&p=1&q=medium) ![View from property](https://images.trvl-media.com/lodging/3000000/2630000/2625800/2625745/2c14a98f.jpg?impolicy=fcrop&w=357&h=201&p=1&q=medium) ### Residence Inn by Marriott Fort Myers Sanibel Fort Myers 8.6/10 Excellent (1003) "Clean room, wonderful staff, and nice breakfast. " ![United States](https://a.travel-assets.com/egds/marks/flags/us.svg) Danielle CA $133 CA $149 total includes taxes & fees Dec 1 - Dec 2 [](https://www.expedia.ca/Fort-Myers-Hotels-Residence-Inn-By-Marriott-Fort-Myers-Sanibel.h2625745.Hotel-Information) ![Outdoor pool](https://images.trvl-media.com/lodging/18000000/17300000/17298900/17298818/w2247h1500x326y0-2ea06bb5.jpg?impolicy=fcrop&w=357&h=201&p=1&q=medium) ![Exterior](https://images.trvl-media.com/lodging/18000000/17300000/17298900/17298818/aa9b23b9.jpg?impolicy=fcrop&w=357&h=201&p=1&q=medium) ![On the beach, sun loungers, beach towels](https://images.trvl-media.com/lodging/18000000/17300000/17298900/17298818/6b3a0fb3.jpg?impolicy=fcrop&w=357&h=201&p=1&q=medium) ![View from property](https://images.trvl-media.com/lodging/18000000/17300000/17298900/17298818/2ab8abc8.jpg?impolicy=fcrop&w=357&h=201&p=1&q=medium) ### Sanibel Island Beach Resort Mid Island 9.0/10 Wonderful (1420) "The room was very clean, great updated bathroom comfortable beds. Great restaurant onsite, beautiful beach. " ![United States](https://a.travel-assets.com/egds/marks/flags/us.svg) Glenda CA $277 CA $345 total includes taxes & fees Dec 18 - Dec 19 [](https://www.expedia.ca/Fort-Myers-Hotels-Sanibel-Island-Beach-Resort.h17298818.Hotel-Information) ![Lobby](https://images.trvl-media.com/lodging/1000000/30000/24300/24286/7a05b6c3.jpg?impolicy=fcrop&w=357&h=201&p=1&q=medium) ![Free daily continental breakfast](https://images.trvl-media.com/lodging/1000000/30000/24300/24286/96b31b3d.jpg?impolicy=fcrop&w=357&h=201&p=1&q=medium) ![1 King Bed Suite w/ Efficiency Non Smoking](https://images.trvl-media.com/lodging/1000000/30000/24300/24286/a487c18b.jpg?impolicy=fcrop&w=357&h=201&p=1&q=medium) ![1 King Bed Studio w/ Sofa-Bed Non Smoking](https://images.trvl-media.com/lodging/1000000/30000/24300/24286/fdc42614.jpg?impolicy=fcrop&w=357&h=201&p=1&q=medium) ### Quality Inn Fort Myers Cape Coral Fort Myers 7.6/10 Good (188) "Good" ![Mexico](https://a.travel-assets.com/egds/marks/flags/mx.svg) Jhoan CA $87 CA $105 total includes taxes & fees Dec 2 - Dec 3 [](https://www.expedia.ca/Fort-Myers-Hotels-Travelodge-By-Wyndham-Fort-Myers.h24286.Hotel-Information) Lowest nightly price found within the past 24 hours based on a 1 night stay for 2 adults. Prices and availability subject to change. Additional terms may apply. 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