Title: Book The Best Hotels in Mousie, KY for 2026from CA $95 - Fully Refundable Options - Hotels.com - Expedia.ca [Vacation Rentals in Mousie](https://expedia.ca/Mousie-Vacation-Rentals.d553248635975849313.Travel-Guide-VacationRentals)[Mousie Car Rentals](https://expedia.ca/Car-Rentals-In-Mousie.d553248635975849313.Car-Rental-Guide)[Mousie Vacation Packages](https://expedia.ca/Mousie.d553248635975849313.Destination-Travel-Guides) ![Default HTG hotel image](https://a.travel-assets.com/travel-assets-manager/fallback-images-brand/bex_lodging_v2.jpg?impolicy=fcrop&w=1200&h=500&q=medium) ![](https://a.travel-assets.com/travel-assets-manager/fallback-images-brand/bex_lodging_v2.jpg?impolicy=fcrop&w=1200&h=500&q=medium) - ![](https://a.travel-assets.com/travel-assets-manager/pictogram-bex/light__calendar_shield.svg) ### Change your mind Book hotels with free cancellation - ![](https://a.travel-assets.com/travel-assets-manager/pictogram-bex/light__deals.svg) ### Treat yourself Sign in to save 10% or more on thousands of hotels [Sign in](https://www.expedia.ca/login) - ![](https://a.travel-assets.com/travel-assets-manager/pictogram-bex/light__bed.svg) ### Be picky Search almost a million properties worldwide ## Go beyond your typical stay in Mousie Pet friendly [](https://www.expedia.ca/Hotel-Search?destination=Mousie%2C+Kentucky%2C+United+States+of+America®ionId=553248635975849313&latLong=37.418432%2C-82.878217&adults=2&startDate=2026-03-03&d1=2026-03-03&endDate=2026-03-05&d2=2026-03-05&amenities=PETS) ## Check prices for these dates Tonight [Feb 17 - Feb 18](https://www.expedia.ca/Hotel-Search?regionId=553248635975849313&startDate=2026-02-17&endDate=2026-02-18&adults=2&rfrr=TG.LP.CheckPrices.Hotel&openPlayBack=true) Tomorrow [Feb 18 - Feb 19](https://www.expedia.ca/Hotel-Search?regionId=553248635975849313&startDate=2026-02-18&endDate=2026-02-19&adults=2&rfrr=TG.LP.CheckPrices.Hotel&openPlayBack=true) This weekend [Feb 20 - Feb 22](https://www.expedia.ca/Hotel-Search?regionId=553248635975849313&startDate=2026-02-20&endDate=2026-02-22&adults=2&rfrr=TG.LP.CheckPrices.Hotel&openPlayBack=true) Next weekend [Feb 27 - Mar 1](https://www.expedia.ca/Hotel-Search?regionId=553248635975849313&startDate=2026-02-27&endDate=2026-03-01&adults=2&rfrr=TG.LP.CheckPrices.Hotel&openPlayBack=true) ## Our top choices for Mousie hotels ![Suite, Multiple Beds, Non Smoking](https://images.trvl-media.com/lodging/1000000/70000/64100/64089/c5e5e779.jpg?impolicy=fcrop&w=357&h=201&p=1&q=medium) ![Lobby](https://images.trvl-media.com/lodging/1000000/70000/64100/64089/61c30ef4.jpg?impolicy=fcrop&w=357&h=201&p=1&q=medium) ![Fitness facility](https://images.trvl-media.com/lodging/1000000/70000/64100/64089/a8eadeaa.jpg?impolicy=fcrop&w=357&h=201&p=1&q=medium) ![Indoor pool](https://images.trvl-media.com/lodging/1000000/70000/64100/64089/dcc5bf6f.jpg?impolicy=fcrop&w=357&h=201&p=1&q=medium) ### Comfort Suites Prestonsburg West [](https://www.expedia.ca/Prestonsburg-Hotels-Comfort-Suites-Prestonsburg-West.h64089.Hotel-Information) Prestonsburg 8.6/10 Excellent (708 reviews) "Love the pool always warm staff is friendly " ![United States](https://a.travel-assets.com/egds/marks/flags/us.svg) Misty CA $149 CA $169 total includes taxes & fees Feb 22 - Feb 23 [](https://www.expedia.ca/Prestonsburg-Hotels-Comfort-Suites-Prestonsburg-West.h64089.Hotel-Information) ![Desk, free WiFi, bed sheets](https://images.trvl-media.com/lodging/14000000/13280000/13279500/13279412/f4cf2616.jpg?impolicy=fcrop&w=357&h=201&p=1&q=medium) ![Property amenity](https://images.trvl-media.com/lodging/14000000/13280000/13279500/13279412/99cfed86.jpg?impolicy=fcrop&w=357&h=201&p=1&q=medium) ![Lobby sitting area](https://images.trvl-media.com/lodging/14000000/13280000/13279500/13279412/2975c150.jpg?impolicy=fcrop&w=357&h=201&p=1&q=medium) ![Children's play area - outdoor](https://images.trvl-media.com/lodging/14000000/13280000/13279500/13279412/bbf28123.jpg?impolicy=fcrop&w=357&h=201&p=1&q=medium) ### Daniel Boone Motor Inn [](https://www.expedia.ca/Prestonsburg-Hotels-Daniel-Boone-Motor-Inn.h13279412.Hotel-Information) Pikeville 7.4/10 Good (390 reviews) "It's exactly what u pay for very quiet as well " ![United States](https://a.travel-assets.com/egds/marks/flags/us.svg) Austin CA $86 CA $95 total includes taxes & fees Feb 19 - Feb 20 [](https://www.expedia.ca/Prestonsburg-Hotels-Daniel-Boone-Motor-Inn.h13279412.Hotel-Information) ![Lobby](https://images.trvl-media.com/lodging/1000000/430000/426000/425922/8a794e51.jpg?impolicy=fcrop&w=357&h=201&p=1&q=medium) ![Reception](https://images.trvl-media.com/lodging/1000000/430000/426000/425922/e2cceff6.jpg?impolicy=fcrop&w=357&h=201&p=1&q=medium) ![Pillowtop beds, desk, iron/ironing board, free cribs/infant beds](https://images.trvl-media.com/lodging/1000000/430000/426000/425922/dbdd83ce.jpg?impolicy=fcrop&w=357&h=201&p=1&q=medium) ![Exterior](https://images.trvl-media.com/lodging/1000000/430000/426000/425922/5619362a.jpg?impolicy=fcrop&w=357&h=201&p=1&q=medium) ### Quality Inn & Suites Prestonsburg next to Mountain Arts Center [](https://www.expedia.ca/Prestonsburg-Hotels-Quality-Inn-Suites.h425922.Hotel-Information) Prestonsburg 8.0/10 Very good (363 reviews) "Staff was courteous and helpful! " ![United States](https://a.travel-assets.com/egds/marks/flags/us.svg) Jessica CA $142 CA $161 total includes taxes & fees Feb 19 - Feb 20 [](https://www.expedia.ca/Prestonsburg-Hotels-Quality-Inn-Suites.h425922.Hotel-Information) ![Desk, iron/ironing board, free WiFi, bed sheets](https://images.trvl-media.com/lodging/1000000/130000/123700/123700/950dfab6.jpg?impolicy=fcrop&w=357&h=201&p=1&q=medium) ![Desk, iron/ironing board, free WiFi, bed sheets](https://images.trvl-media.com/lodging/1000000/130000/123700/123700/4920f52e.jpg?impolicy=fcrop&w=357&h=201&p=1&q=medium) ![Lobby](https://images.trvl-media.com/lodging/1000000/130000/123700/123700/374f0d2c.jpg?impolicy=fcrop&w=357&h=201&p=1&q=medium) ![Free daily on-the-go breakfast](https://images.trvl-media.com/lodging/1000000/130000/123700/123700/e244b4dd.jpg?impolicy=fcrop&w=357&h=201&p=1&q=medium) ### Super 8 by Wyndham Prestonsburg [](https://www.expedia.ca/Prestonsburg-Hotels-Super-8-By-Wyndham-Prestonsburg.h123700.Hotel-Information) Prestonsburg 6.4/10 (527 reviews) "Clean room, friendly staff, and a quick, easy check-in. Exactly what you want from a great stay." ![United States](https://a.travel-assets.com/egds/marks/flags/us.svg) Heather CA $91 CA $101 total includes taxes & fees Feb 23 - Feb 24 [](https://www.expedia.ca/Prestonsburg-Hotels-Super-8-By-Wyndham-Prestonsburg.h123700.Hotel-Information) Lowest nightly price found within the past 24 hours based on a 1 night stay for 2 adults. Prices and availability subject to change. Additional terms may apply. [View all properties](https://expedia.ca/Hotel-Search?startDate=2026-03-03&endDate=2026-03-04®ionId=553248635975849313&adults=2&sort=RECOMMENDED&openPlayBack=true) ![](https://forever.travel-assets.com/flex/flexmanager/images/2026/02/06/expedia-sale-2026-desktop-us-ca.jpg?impolicy=fcrop&w=1400&h=600&q=mediumHigh) ## The Annual Vacation Sale Members save up to 40% on hotels and homes. Plan this year’s big trip and save. [Book now](https://expedia.ca/deals?rfrr=HTG_SPRING_PROMO_553248635975849313) ![](https://a.travel-assets.com/pricing-claim/sparkle_dark.svg) Save an average of 15% on thousands of hotels when you're signed in [Sign in ](https://expedia.ca/user/signin?ckoflag=0&uurl=e3id%3Dredr%26rurl%3D%2FMousie-Hotels.d553248635975849313.Travel-Guide-Hotels)[ Sign up, it's free ](https://expedia.ca/signup?enable_registration=true&+=&uurl=e3id%3Dredr%26rurl%3D%2FMousie-Hotels.d553248635975849313.Travel-Guide-Hotels) ## Top Mousie Hotel Reviews ![Quality Inn & Suites Prestonsburg next to Mountain Arts Center](https://images.trvl-media.com/lodging/1000000/430000/426000/425922/5619362a_y.jpg) ### Quality Inn & Suites Prestonsburg next to Mountain Arts Center 10/10 Excellent "Staff was courteous and helpful! " [](https://expedia.ca/Prestonsburg-Hotels-Quality-Inn-Suites.h425922.Hotel-Information) ![Comfort Suites Prestonsburg West](https://images.trvl-media.com/lodging/1000000/70000/64100/64089/50191acc_y.jpg) ### Comfort Suites Prestonsburg West 10/10 Excellent "Best place we stayed all weekend! Beds were comfortable and staff were friendly. " [](https://expedia.ca/Prestonsburg-Hotels-Comfort-Suites-Prestonsburg-West.h64089.Hotel-Information) ![Daniel Boone Motor Inn](https://images.trvl-media.com/lodging/14000000/13280000/13279500/13279412/bbf28123_y.jpg) ### Daniel Boone Motor Inn 10/10 Excellent "It's exactly what u pay for very quiet as well " [](https://expedia.ca/Prestonsburg-Hotels-Daniel-Boone-Motor-Inn.h13279412.Hotel-Information) ![Super 8 by Wyndham Prestonsburg](https://images.trvl-media.com/lodging/1000000/130000/123700/123700/c55ab847_y.jpg) ### Super 8 by Wyndham Prestonsburg 10/10 Excellent "Clean room, friendly staff, and a quick, easy check-in. Exactly what you want from a great stay." [](https://expedia.ca/Prestonsburg-Hotels-Super-8-By-Wyndham-Prestonsburg.h123700.Hotel-Information) ![Kentucky's Majestic Mountaintop Estate with pool: The Bluegrass Palace](https://images.trvl-media.com/lodging/108000000/107270000/107268200/107268119/b8ad235b_y.jpg) ### Kentucky's Majestic Mountaintop Estate with pool: The Bluegrass Palace 10/10 Excellent "The Palace is awesome! We had 5 families and had a blast hot tubbing, swimming and entertaining Place is so big you can escape when you need to or gather together when you want to " [](https://expedia.ca/Langley-Hotels-Kentuckys-Majestic-Mountaintop-Estate-The-Bluegrass-Palace.h107268119.Hotel-Information) ![Cozy studio on US 23 between Pikeville and Prestonsburg](https://images.trvl-media.com/lodging/109000000/108500000/108494300/108494254/46ce4ae8_y.jpg) ### Cozy studio on US 23 between Pikeville and Prestonsburg 10/10 Excellent "Our host stayed in good contact and the place was very cute and felt super comfortable. We were very happy with our stay :)" [](https://expedia.ca/Cozy-Studio-On-US-23-Between-Pikeville-And-Prestonsburg.h108494254.Hotel-Information) ![Quality Inn & Suites Prestonsburg Next to Mountain Arts Center](https://images.trvl-media.com/lodging/92000000/91630000/91626200/91626121/df0d196e_y.jpg) ### Quality Inn & Suites Prestonsburg Next to Mountain Arts Center 4/10 Poor "The room stunk so bad didn’t realize I booked a smoking room and they couldn’t change it bc I paid with Apple Pay also the room was so small I had to open the windows to air it out " [](https://expedia.ca/Prestonsburg-Hotels-Brookshire-Inn.h91626121.Hotel-Information) ![Cozy Home in Heart of Prestonsburg](https://images.trvl-media.com/lodging/96000000/95520000/95515500/95515447/8a1f321b_y.jpg) ### Cozy Home in Heart of Prestonsburg 10/10 Excellent "We were in town for my Grannys funeral. She grew up in this area. This house was perfect. It was walking distance to downtown. Plenty of room. Nice sized kitchen. Very clean with the peefect backyard for visiting. Will stay here again when we are back in town." [](https://expedia.ca/Prestonsburg-Hotels-Cozy-Home-In-Heart-Of-Prestonsburg.h95515447.Hotel-Information) ![Cozy Tiny Home Quiet 1/1 Close to Riding Trails](https://images.trvl-media.com/lodging/101000000/100540000/100535900/100535857/ea8b7877_y.jpg) ### Cozy Tiny Home Quiet 1/1 Close to Riding Trails 10/10 Excellent "Very nice places. Clean and cute. Love the surrounding Mountain View’s. Definitely on my list to stay again." [](https://expedia.ca/Martin-Hotels-Cozy-Tiny-Home-Quiet-11-Close-To-Riding-Trails.h100535857.Hotel-Information) ## More cheap stays in Mousie ![Daniel Boone Motor Inn](https://images.trvl-media.com/lodging/14000000/13280000/13279500/13279412/bbf28123_y.jpg?impolicy=resizecrop&rw=402&ra=fit) ### Daniel Boone Motor Inn 150 Weddington Branch Road Pikeville KY CA $86 CA $95 total Feb 19 - Feb 20 includes taxes & fees 7.4/10 Good! (390 reviews) [](https://expedia.ca/Prestonsburg-Hotels-Daniel-Boone-Motor-Inn.h13279412.Hotel-Information) ![Super 8 by Wyndham Prestonsburg](https://images.trvl-media.com/lodging/1000000/130000/123700/123700/c55ab847_y.jpg?impolicy=resizecrop&rw=402&ra=fit) ### Super 8 by Wyndham Prestonsburg 80 Shoppers Path Prestonsburg KY CA $91 CA $101 total Feb 23 - Feb 24 includes taxes & fees 6.4/10 (527 reviews) [](https://expedia.ca/Prestonsburg-Hotels-Super-8-By-Wyndham-Prestonsburg.h123700.Hotel-Information) ![Quality Inn & Suites Prestonsburg next to Mountain Arts Center](https://images.trvl-media.com/lodging/1000000/430000/426000/425922/5619362a_y.jpg?impolicy=resizecrop&rw=402&ra=fit) ### Quality Inn & Suites Prestonsburg next to Mountain Arts Center 85 Hal Rogers Drive Prestonsburg KY CA $142 CA $161 total Feb 19 - Feb 20 includes taxes & fees 8/10 Very Good! (363 reviews) [](https://expedia.ca/Prestonsburg-Hotels-Quality-Inn-Suites.h425922.Hotel-Information) ![Comfort Suites Prestonsburg West](https://images.trvl-media.com/lodging/1000000/70000/64100/64089/50191acc_y.jpg?impolicy=resizecrop&rw=402&ra=fit) ### Comfort Suites Prestonsburg West 51 Hal Rogers Dr Prestonsburg KY CA $149 CA $169 total Feb 22 - Feb 23 includes taxes & fees 8.6/10 Excellent! (708 reviews) [](https://expedia.ca/Prestonsburg-Hotels-Comfort-Suites-Prestonsburg-West.h64089.Hotel-Information) ![Quality Inn & Suites Prestonsburg Next to Mountain Arts Center](https://images.trvl-media.com/lodging/92000000/91630000/91626200/91626121/df0d196e_y.jpg?impolicy=resizecrop&rw=402&ra=fit) ### Quality Inn & Suites Prestonsburg Next to Mountain Arts Center 85 Hal Rogers Drive Prestonsburg KY [Get rates](https://expedia.ca/Hotel-Search?startDate=03%2F03%2F2026&endDate=04%2F03%2F2026&selected=91626121&PinnedHotelID=91626121&HadPinnedHotel=true®ionId=553248635975849313) [](https://expedia.ca/Prestonsburg-Hotels-Brookshire-Inn.h91626121.Hotel-Information) ![Cozy studio on US 23 between Pikeville and Prestonsburg](https://images.trvl-media.com/lodging/109000000/108500000/108494300/108494254/46ce4ae8_y.jpg?impolicy=resizecrop&rw=402&ra=fit) ### Cozy studio on US 23 between Pikeville and Prestonsburg Harold KY [Get rates](https://expedia.ca/Hotel-Search?startDate=03%2F03%2F2026&endDate=04%2F03%2F2026&selected=108494254&PinnedHotelID=108494254&HadPinnedHotel=true®ionId=553248635975849313) 9.4/10 Exceptional! (3 reviews) [](https://expedia.ca/Cozy-Studio-On-US-23-Between-Pikeville-And-Prestonsburg.h108494254.Hotel-Information) ## Hotels in Mousie with star rating ![3 Star Hotels](https://images.trvl-media.com/lodging/20000000/19690000/19681400/19681371/84fffc75_z.jpg) 3 Star Hotels 1 properties [](https://expedia.ca/3Star-Mousie-Hotels.s30-0-d553248635975849313.Travel-Guide-Filter-Hotels) ![2 Star Hotels](https://images.trvl-media.com/lodging/92000000/91830000/91828000/91827910/6717a2ac_z.jpg) 2 Star Hotels 6 properties [](https://expedia.ca/2Star-Mousie-Hotels.s20-0-d553248635975849313.Travel-Guide-Filter-Hotels) ## Frequently asked questions ### What is the best area to stay in Mousie? > This area is the heart of Mousie, offering the most convenience for visitors. Main Street is where you'll find the majority of the local shops, eateries, and essential services. It's a compact and easily navigable area, making it simple to get around on foot. > > > For families, staying near Main Street is highly recommended. You'll be close to the local park, which often has play areas for children, and within easy reach of family-friendly restaurants. The convenience of having everything nearby means less travel time and more time enjoying your trip. > > > Couples looking for a relaxed getaway will also appreciate the central location. You can enjoy strolls along Main Street, discover local crafts, and have a choice of places for an evening meal without needing to travel far. ### When is the best time to go to Mousie? > These seasons offer the most comfortable weather for exploring the natural beauty of the region. Spring brings blooming wildflowers and mild temperatures, superb for outdoor activities like hiking and fishing. Autumn showcases stunning fall foliage, making drives through the surrounding hills particularly scenic. ### Can I cancel my hotel reservation on Expedia? ### How can I save on a Mousie hotel booking with Expedia? ### How much is the nightly rate at a Mousie hotel? ## Explore a world of travel with Expedia - Lodging - Flights - Packages - Cars - More ways to book - [1 Star Hotels in Ivel ](https://www.expedia.ca/1Star-Ivel-Hotels.s10-0-d3000438715.Travel-Guide-Filter-Hotels) - [4 Star Hotels in Hi Hat ](https://www.expedia.ca/4Star-Hi-Hat-Hotels.s40-0-d3000438690.Travel-Guide-Filter-Hotels) - [Apartments in Allen ](https://www.expedia.ca/Allen-Apartments.d553248634999234667-aaApartments.Travel-Guide-Accommodation) - [B&B in Allen ](https://www.expedia.ca/Allen-Bed-And-Breakfast.d553248634999234667-aaBedAndBreakfast.Travel-Guide-Accommodation) - [Cabin Rentals in Allen ](https://www.expedia.ca/Allen-Cabins.d553248634999234667-aaCabins.Travel-Guide-Accommodation) - [B&B in Blackey ](https://www.expedia.ca/Blackey-Bed-And-Breakfast.d553248634998793381-aaBedAndBreakfast.Travel-Guide-Accommodation) - 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