Title: Book the Best BUSINESS Hotels in Mississippi Gulf Coast in 2026 | Expedia.ca [Mississippi Gulf Coast Travel Guide](https://expedia.ca/Mississippi-Gulf-Coast.dx6058666)[Hotels in Mississippi Gulf Coast](https://expedia.ca/Mississippi-Gulf-Coast-Hotels.d6058666.Travel-Guide-Hotels)[Vacation Rentals in Mississippi Gulf Coast](https://expedia.ca/Mississippi-Gulf-Coast-Vacation-Rentals.d6058666.Travel-Guide-VacationRentals)[Flights to Mississippi Gulf Coast](https://expedia.ca/Cheap-Flights-To-Mississippi-Gulf-Coast.d6058666.Travel-Guide-Flights)[Things to do in Mississippi Gulf Coast](https://expedia.ca/Things-To-Do-In-Mississippi-Gulf-Coast.d6058666.Travel-Guide-Activities)[Mississippi Gulf Coast Car Rentals](https://expedia.ca/Car-Rentals-In-Mississippi-Gulf-Coast.d6058666.Car-Rental-Guide)[Mississippi Gulf Coast Vacation Packages](https://expedia.ca/Mississippi-Gulf-Coast.d6058666.Destination-Travel-Guides) ![Biloxi showing night scenes and a lighthouse](https://images.trvl-media.com/place/603259/b5fbd0cd-abad-4665-9fe3-f5a5344cf939.jpg?impolicy=fcrop&w=1200&h=500&q=medium) Photo by Mississippi Gulf Coast Convention & Visitors Bureau # Find Business Hotels in Mississippi Gulf Coast, MS from CA $101 - ![](https://a.travel-assets.com/travel-assets-manager/pictogram-bex/light__calendar_shield.svg) ### Change your mind Book hotels with free cancellation - ![](https://a.travel-assets.com/travel-assets-manager/pictogram-bex/light__deals.svg) ### Treat yourself Sign in to save 10% or more on thousands of hotels [Sign in](https://www.expedia.ca/login) - ![](https://a.travel-assets.com/travel-assets-manager/pictogram-bex/light__bed.svg) ### Be picky Search almost a million properties worldwide ## Check availability on Mississippi Gulf Coast Business Hotels Tonight [Dec 27 - Dec 28](https://www.expedia.ca/Hotel-Search?regionId=6058666&startDate=2025-12-27&endDate=2025-12-28&adults=2&rfrr=TG.LP.CheckPrices.Hotel&openPlayBack=true&travelerType=business_friendly) Tomorrow [Dec 28 - Dec 29](https://www.expedia.ca/Hotel-Search?regionId=6058666&startDate=2025-12-28&endDate=2025-12-29&adults=2&rfrr=TG.LP.CheckPrices.Hotel&openPlayBack=true&travelerType=business_friendly) Next weekend [Jan 2 - Jan 4](https://www.expedia.ca/Hotel-Search?regionId=6058666&startDate=2026-01-02&endDate=2026-01-04&adults=2&rfrr=TG.LP.CheckPrices.Hotel&openPlayBack=true&travelerType=business_friendly) In two weeks [Jan 9 - Jan 11](https://www.expedia.ca/Hotel-Search?regionId=6058666&startDate=2026-01-09&endDate=2026-01-11&adults=2&rfrr=TG.LP.CheckPrices.Hotel&openPlayBack=true&travelerType=business_friendly) ## Our top choices for Mississippi Gulf Coast business-friendly hotels ![2 outdoor pools, cabanas (surcharge), pool umbrellas](https://images.trvl-media.com/lodging/1000000/30000/22300/22267/0e82f306.jpg?impolicy=fcrop&w=357&h=201&p=1&q=medium) ![Junior Suite, 1 King Bed, Non Smoking](https://images.trvl-media.com/lodging/1000000/30000/22300/22267/0fca225c.jpg?impolicy=fcrop&w=357&h=201&p=1&q=medium) ![Exterior](https://images.trvl-media.com/lodging/1000000/30000/22300/22267/0cbf294f.jpg?impolicy=fcrop&w=357&h=201&p=1&q=medium) ![Casino](https://images.trvl-media.com/lodging/1000000/30000/22300/22267/e4c76492.jpg?impolicy=fcrop&w=357&h=201&p=1&q=medium) ### Golden Nugget Biloxi [](https://www.expedia.ca/Biloxi-Hotels-Golden-Nugget-Biloxi.h22267.Hotel-Information) Downtown Biloxi 8.0/10 Very good (2764) "Check in, room and restaurants were great" ![United States](https://a.travel-assets.com/egds/marks/flags/us.svg) Julia CA $98 CA $134 total includes taxes & fees Jan 21 - Jan 22, 2026 [](https://www.expedia.ca/Biloxi-Hotels-Golden-Nugget-Biloxi.h22267.Hotel-Information) ![Outdoor pool, open 8:00 AM to 10:00 PM, cabanas (surcharge)](https://images.trvl-media.com/lodging/2000000/1660000/1652900/1652862/6049152a.jpg?impolicy=fcrop&w=357&h=201&p=1&q=medium) ![Premium bedding, in-room safe, desk, laptop workspace](https://images.trvl-media.com/lodging/2000000/1660000/1652900/1652862/298d55e8.jpg?impolicy=fcrop&w=357&h=201&p=1&q=medium) ![Marina](https://images.trvl-media.com/lodging/2000000/1660000/1652900/1652862/bf4d999e.jpg?impolicy=fcrop&w=357&h=201&p=1&q=medium) ![Deep-tissue massages, Swedish massages, body scrubs, facials](https://images.trvl-media.com/lodging/2000000/1660000/1652900/1652862/2c58a908.jpg?impolicy=fcrop&w=357&h=201&p=1&q=medium) ### Palace Casino Resort [](https://www.expedia.ca/Biloxi-Hotels-Palace-Casino-Resort.h1652862.Hotel-Information) Summerville 9.2/10 Wonderful (3007) "Clean rooms, good food, great staff" ![United States](https://a.travel-assets.com/egds/marks/flags/us.svg) Chris CA $92 CA $104 total includes taxes & fees Jan 4 - Jan 5, 2026 [](https://www.expedia.ca/Biloxi-Hotels-Palace-Casino-Resort.h1652862.Hotel-Information) ![Exterior](https://images.trvl-media.com/lodging/1000000/70000/67100/67068/5a7f80d4.jpg?impolicy=fcrop&w=357&h=201&p=1&q=medium) ![8 restaurants, breakfast, lunch, dinner served; local cuisine](https://images.trvl-media.com/lodging/1000000/70000/67100/67068/420464c2.jpg?impolicy=fcrop&w=357&h=201&p=1&q=medium) ![Front of property - evening/night](https://images.trvl-media.com/lodging/1000000/70000/67100/67068/b5e735d1.jpg?impolicy=fcrop&w=357&h=201&p=1&q=medium) ![Outdoor pool, cabanas (surcharge), sun loungers](https://images.trvl-media.com/lodging/1000000/70000/67100/67068/667b46a3.jpg?impolicy=fcrop&w=357&h=201&p=1&q=medium) ### Harrah’s Gulf Coast – A Caesars Rewards Destination [](https://www.expedia.ca/Biloxi-Hotels-Harrahs-Gulf-Coast.h67068.Hotel-Information) Summerville 7.6/10 Good (1394) "Room is great" ![United States](https://a.travel-assets.com/egds/marks/flags/us.svg) Steven CA $64 CA $101 total includes taxes & fees Jan 15 - Jan 16, 2026 [](https://www.expedia.ca/Biloxi-Hotels-Harrahs-Gulf-Coast.h67068.Hotel-Information) ![Exterior](https://images.trvl-media.com/lodging/45000000/44560000/44550300/44550296/4393bc4f.jpg?impolicy=fcrop&w=357&h=201&p=1&q=medium) ![Lobby](https://images.trvl-media.com/lodging/45000000/44560000/44550300/44550296/bed9eb06.jpg?impolicy=fcrop&w=357&h=201&p=1&q=medium) ![Lobby sitting area](https://images.trvl-media.com/lodging/45000000/44560000/44550300/44550296/5fb21ef3.jpg?impolicy=fcrop&w=357&h=201&p=1&q=medium) ![Outdoor pool, open 7:00 AM to 10:00 PM, free cabanas, sun loungers](https://images.trvl-media.com/lodging/45000000/44560000/44550300/44550296/ecf9035d.jpg?impolicy=fcrop&w=357&h=201&p=1&q=medium) ### The Hotel Legends [](https://www.expedia.ca/Biloxi-Hotels-The-Hotel-Legends.h44550296.Hotel-Information) Downtown Biloxi 9.6/10 Exceptional (2555) "Easy checkin and room was clean. " ![United States](https://a.travel-assets.com/egds/marks/flags/us.svg) Karen CA $132 CA $162 total includes taxes & fees Jan 4 - Jan 5, 2026 [](https://www.expedia.ca/Biloxi-Hotels-The-Hotel-Legends.h44550296.Hotel-Information) ![Mini-golf](https://images.trvl-media.com/lodging/20000000/19670000/19661600/19661502/a73e79ff.jpg?impolicy=fcrop&w=357&h=201&p=1&q=medium) ![Premium bedding, pillowtop beds, in-room safe, desk](https://images.trvl-media.com/lodging/20000000/19670000/19661600/19661502/6336c7cf.jpg?impolicy=fcrop&w=357&h=201&p=1&q=medium) ![Premium bedding, pillowtop beds, in-room safe, desk](https://images.trvl-media.com/lodging/20000000/19670000/19661600/19661502/62ad0b38.jpg?impolicy=fcrop&w=357&h=201&p=1&q=medium) ![Casino](https://images.trvl-media.com/lodging/20000000/19670000/19661600/19661502/bf793690.jpg?impolicy=fcrop&w=357&h=201&p=1&q=medium) ### Scarlet Pearl Casino Resort [](https://www.expedia.ca/Biloxi-Hotels-Scarlet-Pearl-Casino-Resort.h19661502.Hotel-Information) D'Iberville 9.4/10 Exceptional (1576) "Beautiful hotel and casino" ![United States](https://a.travel-assets.com/egds/marks/flags/us.svg) John [](https://www.expedia.ca/Biloxi-Hotels-Scarlet-Pearl-Casino-Resort.h19661502.Hotel-Information) ![Outdoor pool, open 10:00 AM to 10:00 PM, pool umbrellas, sun loungers](https://images.trvl-media.com/lodging/6000000/5090000/5087900/5087816/w5496h3667x0y0-52564eca.jpg?impolicy=fcrop&w=357&h=201&p=1&q=medium) ![Point of interest](https://images.trvl-media.com/lodging/6000000/5090000/5087900/5087816/3d4eedfd.jpg?impolicy=fcrop&w=357&h=201&p=1&q=medium) ![Exterior](https://images.trvl-media.com/lodging/6000000/5090000/5087900/5087816/18b567ac.jpg?impolicy=fcrop&w=357&h=201&p=1&q=medium) ![Free daily continental breakfast](https://images.trvl-media.com/lodging/6000000/5090000/5087900/5087816/e49fea8b.jpg?impolicy=fcrop&w=357&h=201&p=1&q=medium) ### Holiday Inn Express Gulfport Beach by IHG [](https://www.expedia.ca/Biloxi-Hotels-Holiday-Inn-Express-Gulfport-Beach.h5087816.Hotel-Information) Gulfport 9.4/10 Exceptional (792) "Very nice staff and very clean rooms. " ![United States](https://a.travel-assets.com/egds/marks/flags/us.svg) josh CA $146 CA $164 total includes taxes & fees Jan 9 - Jan 10, 2026 [](https://www.expedia.ca/Biloxi-Hotels-Holiday-Inn-Express-Gulfport-Beach.h5087816.Hotel-Information) ![Exterior](https://images.trvl-media.com/lodging/9000000/8760000/8751700/8751651/w1998h2492x0y8-c9ab34b7.jpg?impolicy=fcrop&w=357&h=201&p=1&q=medium) ![Exterior](https://images.trvl-media.com/lodging/9000000/8760000/8751700/8751651/cf758231.jpg?impolicy=fcrop&w=357&h=201&p=1&q=medium) ![Lobby lounge](https://images.trvl-media.com/lodging/9000000/8760000/8751700/8751651/ff7d4212.jpg?impolicy=fcrop&w=357&h=201&p=1&q=medium) ![Lobby sitting area](https://images.trvl-media.com/lodging/9000000/8760000/8751700/8751651/34322367.jpg?impolicy=fcrop&w=357&h=201&p=1&q=medium) ### White House Hotel [](https://www.expedia.ca/Biloxi-Hotels-White-House-Hotel.h8751651.Hotel-Information) Biloxi 8.8/10 Excellent (1000) "Yes, great stay. " ![United States](https://a.travel-assets.com/egds/marks/flags/us.svg) Ian CA $150 CA $168 total includes taxes & fees Jan 4 - Jan 5, 2026 [](https://www.expedia.ca/Biloxi-Hotels-White-House-Hotel.h8751651.Hotel-Information) ![Outdoor pool, a heated pool](https://images.trvl-media.com/lodging/17000000/16130000/16127500/16127483/482651a7.jpg?impolicy=fcrop&w=357&h=201&p=1&q=medium) ![Premium bedding, in-room safe, desk, iron/ironing board](https://images.trvl-media.com/lodging/17000000/16130000/16127500/16127483/0e5d93fc.jpg?impolicy=fcrop&w=357&h=201&p=1&q=medium) ![Bar (on property)](https://images.trvl-media.com/lodging/17000000/16130000/16127500/16127483/8a0208a3.jpg?impolicy=fcrop&w=357&h=201&p=1&q=medium) ![Exterior](https://images.trvl-media.com/lodging/17000000/16130000/16127500/16127483/d498ef2a.jpg?impolicy=fcrop&w=357&h=201&p=1&q=medium) ### Hyatt Place Biloxi [](https://www.expedia.ca/Biloxi-Hotels-Hyatt-Place-Biloxi.h16127483.Hotel-Information) Biloxi 8.8/10 Excellent (1209) "Spotless room, great breakfast friendly staff " ![United States](https://a.travel-assets.com/egds/marks/flags/us.svg) deborah CA $133 CA $149 total includes taxes & fees Jan 5 - Jan 6, 2026 [](https://www.expedia.ca/Biloxi-Hotels-Hyatt-Place-Biloxi.h16127483.Hotel-Information) ![Room, 2 Queen Beds, Accessible, Non Smoking (Mobility Accessible)](https://images.trvl-media.com/lodging/10000000/9130000/9127800/9127721/810c7703.jpg?impolicy=fcrop&w=357&h=201&p=1&q=medium) ![Free daily continental breakfast](https://images.trvl-media.com/lodging/10000000/9130000/9127800/9127721/b4a284f7.jpg?impolicy=fcrop&w=357&h=201&p=1&q=medium) ![Outdoor pool, sun loungers](https://images.trvl-media.com/lodging/10000000/9130000/9127800/9127721/953e6e18.jpg?impolicy=fcrop&w=357&h=201&p=1&q=medium) ![Exterior](https://images.trvl-media.com/lodging/10000000/9130000/9127800/9127721/7ee5474d.jpg?impolicy=fcrop&w=357&h=201&p=1&q=medium) ### La Quinta Inn & Suites by Wyndham Hattiesburg - I-59 [](https://www.expedia.ca/Hattiesburg-Hotels-La-Quinta-Inn-Suites-By-Wyndham-Hattiesburg-I-59.h9127721.Hotel-Information) Hattiesburg 8.6/10 Excellent (1518) "We have stayed there a couple of times and the beds are awesome. It is our half way point traveling to Orlando (to see our daughter and grandson). " ![United States](https://a.travel-assets.com/egds/marks/flags/us.svg) John CA $100 CA $110 total includes taxes & fees Jan 18 - Jan 19, 2026 [](https://www.expedia.ca/Hattiesburg-Hotels-La-Quinta-Inn-Suites-By-Wyndham-Hattiesburg-I-59.h9127721.Hotel-Information) ![Seasonal outdoor pool, open 9:00 AM to 8:00 PM, sun loungers](https://images.trvl-media.com/lodging/38000000/37080000/37075200/37075152/3568a8ed.jpg?impolicy=fcrop&w=357&h=201&p=1&q=medium) ![Mini-golf](https://images.trvl-media.com/lodging/38000000/37080000/37075200/37075152/959fd175.jpg?impolicy=fcrop&w=357&h=201&p=1&q=medium) ![Exterior](https://images.trvl-media.com/lodging/38000000/37080000/37075200/37075152/b7ffd230.jpg?impolicy=fcrop&w=357&h=201&p=1&q=medium) ![Lobby](https://images.trvl-media.com/lodging/38000000/37080000/37075200/37075152/aabb4188.jpg?impolicy=fcrop&w=357&h=201&p=1&q=medium) ### Centennial Plaza Resort Gulfport [](https://www.expedia.ca/Biloxi-Hotels-Grand-Centennial-Hotel-Gulfport.h37075152.Hotel-Information) Gulfport 9.2/10 Wonderful (1000) "This was an excellent place to stay ! Extremely well maintained , clean and very friendly staff !!!! " ![United States](https://a.travel-assets.com/egds/marks/flags/us.svg) Steve CA $146 CA $191 total includes taxes & fees Jan 4 - Jan 5, 2026 [](https://www.expedia.ca/Biloxi-Hotels-Grand-Centennial-Hotel-Gulfport.h37075152.Hotel-Information) Lowest nightly price found within the past 24 hours based on a 1 night stay for 2 adults. Prices and availability subject to change. Additional terms may apply. [View all properties](https://expedia.ca/Hotel-Search?startDate=2026-01-10&endDate=2026-01-11®ionId=6058666&adults=2&travelerType=business_friendly&sort=RECOMMENDED&openPlayBack=true) ## Top Mississippi Gulf Coast Hotel Reviews ![Comfort Suites Gulfport](https://images.trvl-media.com/lodging/3000000/2960000/2958800/2958794/5de09bb8_y.jpg) ### Comfort Suites Gulfport 10/10 Excellent "The room was clean and spacious. The breakfast was delicious. My children enjoy the stay aswell. " [](https://expedia.ca/Biloxi-Hotels-Comfort-Suites-Gulfport.h2958794.Hotel-Information) ![Harrah’s Gulf Coast – A Caesars Rewards Destination](https://images.trvl-media.com/lodging/1000000/70000/67100/67068/5a7f80d4_y.jpg) ### Harrah’s Gulf Coast – A Caesars Rewards Destination 10/10 Excellent "Staff professional, courteous, knowledgeable and very patient. Got great room with view of ocean. Nice casino, everything you need is here." [](https://expedia.ca/Biloxi-Hotels-Harrahs-Gulf-Coast.h67068.Hotel-Information) ![Golden Nugget Biloxi](https://images.trvl-media.com/lodging/1000000/30000/22300/22267/0e82f306_y.jpg) ### Golden Nugget Biloxi 10/10 Excellent "The room was spacious and clean. The staff were very courteous and showed great customer service. I will definitely book again! Thank You!" [](https://expedia.ca/Biloxi-Hotels-Golden-Nugget-Biloxi.h22267.Hotel-Information) ![Beau Rivage](https://images.trvl-media.com/lodging/1000000/200000/199700/199634/b66654c5_y.jpg) ### Beau Rivage 10/10 Excellent "The room was beautiful and the staff were exceptional. We experienced wonderful customer service. " [](https://expedia.ca/Biloxi-Hotels-Beau-Rivage.h199634.Hotel-Information) ![Hampton Inn & Suites Gulfport I-10](https://images.trvl-media.com/lodging/9000000/8080000/8075600/8075559/682c2162_y.jpg) ### Hampton Inn & Suites Gulfport I-10 10/10 Excellent "Room was clean:) friendly staff:)" [](https://expedia.ca/Biloxi-Hotels-Hampton-Inn-Suites-Gulfport.h8075559.Hotel-Information) ![IP Casino Resort Spa - Biloxi](https://images.trvl-media.com/lodging/1000000/90000/85100/85080/e0a1ead8_y.jpg) ### IP Casino Resort Spa - Biloxi 10/10 Excellent "Room was well kept and stocked. We ordered room service and it was fantastic ! We did not use any of the casino services but the hotel and places within had fantastic staff and great food. " [](https://expedia.ca/Biloxi-Hotels-IP-Casino-Resort-Spa-Biloxi.h85080.Hotel-Information) ![Hard Rock Hotel & Casino Biloxi](https://images.trvl-media.com/lodging/2000000/1740000/1731600/1731566/7e1bb110_y.jpg) ### Hard Rock Hotel & Casino Biloxi 10/10 Excellent "Clean room, good service" [](https://expedia.ca/Biloxi-Hotels-Hard-Rock-Hotel-Casino-Biloxi.h1731566.Hotel-Information) ![Hyatt Place Biloxi](https://images.trvl-media.com/lodging/17000000/16130000/16127500/16127483/482651a7_y.jpg) ### Hyatt Place Biloxi 10/10 Excellent "The staff was courteous and the room was clean. The lobby area was nice. The food from the bar was also good. Will definitely stay again. " [](https://expedia.ca/Biloxi-Hotels-Hyatt-Place-Biloxi.h16127483.Hotel-Information) ![Margaritaville Resort Biloxi](https://images.trvl-media.com/lodging/16000000/15610000/15602500/15602500/b9c2b2c6_y.jpg) ### Margaritaville Resort Biloxi 10/10 Excellent "Beautiful balcony room, comfortable beds, clean room and hallway areas. " [](https://expedia.ca/Biloxi-Hotels-Margaritaville-Resort-Biloxi.h15602500.Hotel-Information) ## Frequently asked questions ### How much do business-friendly hotels in Mississippi Gulf Coast cost? ### What are the best business-friendly hotels in Mississippi Gulf Coast? ### How many business-friendly hotels are there in Mississippi Gulf Coast? ### What are the best cheap business-friendly hotels in Mississippi Gulf Coast? ### Are there any family-friendly hotels in Mississippi Gulf Coast that are also business friendly? ### Are there any 5-star business-friendly hotels in Mississippi Gulf Coast? ### Why book your business-friendly hotel in Mississippi Gulf Coast with Expedia? ### How can I find cheap business-friendly hotels in Mississippi Gulf Coast? ### What is there to do in Mississippi Gulf Coast near my business-friendly hotel? ## Explore a world of travel with Expedia - Lodging - Flights - Packages - Cars - More ways to book - [Adults Only Resorts & in Bayou View ](https://www.expedia.ca/Bayou-View-Gulfport-Hotels-Adults-Only-Resorts.0-n553248635976473839-0-tAdultsOnlyResorts.Travel-Guide-Filter-Hotels) - 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