Title: Book the Best Mission Valley SPA Resorts from CA $163 - Spa Hotels in Mission Valley, San Diego | Expedia.ca [Vacation Rentals in San Diego](https://expedia.ca/San-Diego-Vacation-Rentals.d3073.Travel-Guide-VacationRentals)[Flights to San Diego](https://expedia.ca/Cheap-Flights-To-San-Diego.d3073.Travel-Guide-Flights)[Things to do in San Diego](https://expedia.ca/Things-To-Do-In-San-Diego.d3073.Travel-Guide-Activities)[Mission Valley Car Rentals](https://expedia.ca/Car-Rentals-In-Mission-Valley.d800124.Car-Rental-Guide)[Mission Valley Vacations](https://expedia.ca/Mission-Valley.d800124.Destination-Travel-Guides) ![](https://mediaim.expedia.com/destination/1/c9e921ee48ed278ba029d508e2d24762.jpg?impolicy=fcrop&w=1200&h=500&q=medium) # Find Spa Hotels in Mission Valley, San Diego from CA $163 ![](https://a.travel-assets.com/travel-assets-manager/pictogram-bex/light__calendar_shield.svg) ### Change your mind Book hotels with free cancellation ![](https://a.travel-assets.com/travel-assets-manager/pictogram-bex/light__deals.svg) ### Treat yourself Sign in to save 10% or more on thousands of hotels [Sign in](https://www.expedia.ca/login) ![](https://a.travel-assets.com/travel-assets-manager/pictogram-bex/light__bed.svg) ### Be picky Search almost a million properties worldwide ## Check availability on Mission Valley Spa Hotels Tonight [Oct 30 - Oct 31](https://www.expedia.ca/Hotel-Search?regionId=800124&startDate=2025-10-30&endDate=2025-10-31&adults=2&amenities=SPA_ON_SITE&rfrr=TG.LP.CheckPrices.Hotel&openPlayBack=true) Tomorrow [Oct 31 - Nov 1](https://www.expedia.ca/Hotel-Search?regionId=800124&startDate=2025-10-31&endDate=2025-11-01&adults=2&amenities=SPA_ON_SITE&rfrr=TG.LP.CheckPrices.Hotel&openPlayBack=true) This weekend [Oct 31 - Nov 2](https://www.expedia.ca/Hotel-Search?regionId=800124&startDate=2025-10-31&endDate=2025-11-02&adults=2&amenities=SPA_ON_SITE&rfrr=TG.LP.CheckPrices.Hotel&openPlayBack=true) Next weekend [Nov 7 - Nov 9](https://www.expedia.ca/Hotel-Search?regionId=800124&startDate=2025-11-07&endDate=2025-11-09&adults=2&amenities=SPA_ON_SITE&rfrr=TG.LP.CheckPrices.Hotel&openPlayBack=true) ## Top Mission Valley Spa Hotels ![Couples treatment rooms, body treatments, hot stone massages](https://images.trvl-media.com/lodging/42000000/41510000/41504800/41504735/cba9a8a4.jpg?impolicy=fcrop&w=357&h=201&p=1&q=medium) ![Lobby](https://images.trvl-media.com/lodging/42000000/41510000/41504800/41504735/43ef19cb.jpg?impolicy=fcrop&w=357&h=201&p=1&q=medium) ![Garden](https://images.trvl-media.com/lodging/42000000/41510000/41504800/41504735/0bbd67f4.jpg?impolicy=fcrop&w=357&h=201&p=1&q=medium) ![Restaurant](https://images.trvl-media.com/lodging/42000000/41510000/41504800/41504735/21efa256.jpg?impolicy=fcrop&w=357&h=201&p=1&q=medium) ### Legacy Resort Hotel & Spa Mission Valley 9.2/10 Wonderful (2923) "Great stay" ![United States](https://a.travel-assets.com/egds/marks/flags/us.svg) Songkwon CA $238 CA $274 total includes taxes & fees Nov 10 - Nov 11 [](https://www.expedia.ca/San-Diego-Hotels-Legacy-Resort-Hotel-Spa.h41504735.Hotel-Information) ![Premier Room, 1 King Bed](https://images.trvl-media.com/lodging/1000000/10000/8400/8374/fde0003f.jpg?impolicy=fcrop&w=357&h=201&p=1&q=medium) ![Premium bedding, in-room safe, desk, blackout drapes](https://images.trvl-media.com/lodging/1000000/10000/8400/8374/76794add.jpg?impolicy=fcrop&w=357&h=201&p=1&q=medium) ![Outdoor pool, pool umbrellas, sun loungers](https://images.trvl-media.com/lodging/1000000/10000/8400/8374/ab6ccd55.jpg?impolicy=fcrop&w=357&h=201&p=1&q=medium) ![Outdoor banquet area](https://images.trvl-media.com/lodging/1000000/10000/8400/8374/6257cb78.jpg?impolicy=fcrop&w=357&h=201&p=1&q=medium) ### Handlery Hotel Mission Valley 8.2/10 Very good (2187) "The hotel is very clean, pool and spa are fantastic, the food at the hotel was excellent " ![United States](https://a.travel-assets.com/egds/marks/flags/us.svg) Eugene CA $142 CA $163 total includes taxes & fees Nov 5 - Nov 6 [](https://www.expedia.ca/San-Diego-Hotels-Handlery-Hotel.h8374.Hotel-Information) ![Exterior](https://images.trvl-media.com/lodging/1000000/10000/900/858/c5325c92.jpg?impolicy=fcrop&w=357&h=201&p=1&q=medium) ![Down comforters, pillowtop beds, in-room safe, desk](https://images.trvl-media.com/lodging/1000000/10000/900/858/93b051f7.jpg?impolicy=fcrop&w=357&h=201&p=1&q=medium) ![Front of property](https://images.trvl-media.com/lodging/1000000/10000/900/858/c6795882.jpg?impolicy=fcrop&w=357&h=201&p=1&q=medium) ![Penthouse](https://images.trvl-media.com/lodging/1000000/10000/900/858/36c2b78d.jpg?impolicy=fcrop&w=357&h=201&p=1&q=medium) ### Hyatt Regency Mission Bay Spa and Marina Mission Bay 8.4/10 Very good (1562) "Clean rooms great view amazing pool and we loved the breakfast " ![United States](https://a.travel-assets.com/egds/marks/flags/us.svg) ad CA $236 CA $345 total includes taxes & fees Oct 31 - Nov 1 [](https://www.expedia.ca/San-Diego-Hotels-Hyatt-Regency-Mission-Bay-Spa-And-Marina.h858.Hotel-Information) ![Dinner served](https://images.trvl-media.com/lodging/1000000/990000/982500/982408/41f8be82.jpg?impolicy=fcrop&w=357&h=201&p=1&q=medium) ![Lobby sitting area](https://images.trvl-media.com/lodging/1000000/990000/982500/982408/a9075ad6.jpg?impolicy=fcrop&w=357&h=201&p=1&q=medium) ![Dinner served](https://images.trvl-media.com/lodging/1000000/990000/982500/982408/029abbb9.jpg?impolicy=fcrop&w=357&h=201&p=1&q=medium) ![Rooftop terrace](https://images.trvl-media.com/lodging/1000000/990000/982500/982408/169b339e.jpg?impolicy=fcrop&w=357&h=201&p=1&q=medium) ### Omni San Diego Hotel at the Ballpark Downtown San Diego 9.2/10 Wonderful (2049) "Love this hotel, wonderful staff and location " ![United States](https://a.travel-assets.com/egds/marks/flags/us.svg) Caroline CA $255 CA $359 total includes taxes & fees Nov 23 - Nov 24 [](https://www.expedia.ca/San-Diego-Hotels-Omni-San-Diego-Hotel.h982408.Hotel-Information) ![Facials, 2 treatment rooms, massages](https://images.trvl-media.com/lodging/1000000/30000/27600/27516/920d9520.jpg?impolicy=fcrop&w=357&h=201&p=1&q=medium) ![Hospitality Suite, 1 King Bed, Bay View | Living room](https://images.trvl-media.com/lodging/1000000/30000/27600/27516/d02824a2.jpg?impolicy=fcrop&w=357&h=201&p=1&q=medium) ![Beach nearby, white sand](https://images.trvl-media.com/lodging/1000000/30000/27600/27516/31f9c777.jpg?impolicy=fcrop&w=357&h=201&p=1&q=medium) ![1 bedroom, premium bedding, pillowtop beds, in-room safe](https://images.trvl-media.com/lodging/1000000/30000/27600/27516/ca66f35a.jpg?impolicy=fcrop&w=357&h=201&p=1&q=medium) ### The Westin San Diego Bayview Downtown San Diego 8.6/10 Excellent (1018) "Rooms were clean, staff were pleasant and helpful. Enjoyed our stay." ![United States](https://a.travel-assets.com/egds/marks/flags/us.svg) Maretin CA $189 CA $259 total includes taxes & fees Nov 24 - Nov 25 [](https://www.expedia.ca/San-Diego-Hotels-The-Westin-San-Diego-Downtown.h27516.Hotel-Information) ![Fitness studio](https://images.trvl-media.com/lodging/34000000/33670000/33661500/33661441/8d3908bb.jpg?impolicy=fcrop&w=357&h=201&p=1&q=medium) ![1 bedroom, hypo-allergenic bedding, down comforters, pillowtop beds](https://images.trvl-media.com/lodging/34000000/33670000/33661500/33661441/8995625e.jpg?impolicy=fcrop&w=357&h=201&p=1&q=medium) ![7 restaurants, breakfast served](https://images.trvl-media.com/lodging/34000000/33670000/33661500/33661441/250333ae.jpg?impolicy=fcrop&w=357&h=201&p=1&q=medium) ![Property grounds](https://images.trvl-media.com/lodging/34000000/33670000/33661500/33661441/91cdc1c7.jpg?impolicy=fcrop&w=357&h=201&p=1&q=medium) ### Sycuan Casino Resort El Cajon 9.2/10 Wonderful (1595) "Great resort!" ![United States](https://a.travel-assets.com/egds/marks/flags/us.svg) Vicky [](https://www.expedia.ca/El-Cajon-Hotels-Sycuan-Casino-Resort.h33661441.Hotel-Information) ![Body treatments, aromatherapy, body wraps, body scrubs, facials](https://images.trvl-media.com/lodging/2000000/1880000/1871700/1871645/b1fc21d4.jpg?impolicy=fcrop&w=357&h=201&p=1&q=medium) ![Outdoor pool, sun loungers](https://images.trvl-media.com/lodging/2000000/1880000/1871700/1871645/9fc82331.jpg?impolicy=fcrop&w=357&h=201&p=1&q=medium) ![2 bars/lounges, lobby lounge](https://images.trvl-media.com/lodging/2000000/1880000/1871700/1871645/ed2e1ba0.jpg?impolicy=fcrop&w=357&h=201&p=1&q=medium) ![Breakfast, lunch, dinner served; Californian cuisine, ocean views ](https://images.trvl-media.com/lodging/2000000/1880000/1871700/1871645/06f19e3f.jpg?impolicy=fcrop&w=357&h=201&p=1&q=medium) ### Hilton San Diego Bayfront Downtown San Diego 8.6/10 Excellent (1795) "Clean room, beautiful views, great staff… excellent hotel and beautiful city!" ![United States](https://a.travel-assets.com/egds/marks/flags/us.svg) Kristan CA $188 CA $286 total includes taxes & fees Nov 25 - Nov 26 [](https://www.expedia.ca/San-Diego-Hotels-Hilton-San-Diego-Bayfront.h1871645.Hotel-Information) ![Reception](https://images.trvl-media.com/lodging/1000000/10000/9700/9660/8496a8ba.jpg?impolicy=fcrop&w=357&h=201&p=1&q=medium) ![Hypo-allergenic bedding, in-room safe, iron/ironing board](https://images.trvl-media.com/lodging/1000000/10000/9700/9660/3af899ba.jpg?impolicy=fcrop&w=357&h=201&p=1&q=medium) ![Exterior](https://images.trvl-media.com/lodging/1000000/10000/9700/9660/9de092e2.jpg?impolicy=fcrop&w=357&h=201&p=1&q=medium) ![Hypo-allergenic bedding, in-room safe, iron/ironing board](https://images.trvl-media.com/lodging/1000000/10000/9700/9660/5c2bbbc6.jpg?impolicy=fcrop&w=357&h=201&p=1&q=medium) ### Best Western Plus Island Palms Hotel & Marina Point Loma 8.8/10 Excellent (1568) "Staff were great and friendly, good food and drink, clean and good central location. " ![Australia](https://a.travel-assets.com/egds/marks/flags/au.svg) Mick CA $166 CA $191 total includes taxes & fees Nov 23 - Nov 24 [](https://www.expedia.ca/San-Diego-Hotels-Best-Western-Plus-Island-Palms-Hotel-Marina.h9660.Hotel-Information) ![Couples treatment rooms, sauna, hot tub, steam room, body treatments](https://images.trvl-media.com/lodging/1000000/30000/25900/25840/d9cbfe80.jpg?impolicy=fcrop&w=357&h=201&p=1&q=medium) ![3 outdoor pools, cabanas (surcharge), pool umbrellas](https://images.trvl-media.com/lodging/1000000/30000/25900/25840/c2540b7d.jpg?impolicy=fcrop&w=357&h=201&p=1&q=medium) ![Exterior](https://images.trvl-media.com/lodging/1000000/30000/25900/25840/c2d82864.jpg?impolicy=fcrop&w=357&h=201&p=1&q=medium) ![Staircase](https://images.trvl-media.com/lodging/1000000/30000/25900/25840/423e7241.jpg?impolicy=fcrop&w=357&h=201&p=1&q=medium) ### Loews Coronado Bay Resort Silver Strand 8.8/10 Excellent (1049) "Beautiful grounds and friendly staff " ![United States](https://a.travel-assets.com/egds/marks/flags/us.svg) Margarita CA $278 CA $372 total includes taxes & fees Nov 23 - Nov 24 [](https://www.expedia.ca/Coronado-Hotels-Loews-Coronado-Bay-Resort.h25840.Hotel-Information) ![Outdoor pool](https://images.trvl-media.com/lodging/1000000/40000/36200/36183/7cb5b7d9.jpg?impolicy=fcrop&w=357&h=201&p=1&q=medium) ![Marina](https://images.trvl-media.com/lodging/1000000/40000/36200/36183/f0d27d94.jpg?impolicy=fcrop&w=357&h=201&p=1&q=medium) ![Sundeck](https://images.trvl-media.com/lodging/1000000/40000/36200/36183/52554aaa.jpg?impolicy=fcrop&w=357&h=201&p=1&q=medium) ![Reception](https://images.trvl-media.com/lodging/1000000/40000/36200/36183/cc6aac5f.jpg?impolicy=fcrop&w=357&h=201&p=1&q=medium) ### Humphreys Half Moon Inn Point Loma 9.2/10 Wonderful (2597) "Great hotel. " ![United States](https://a.travel-assets.com/egds/marks/flags/us.svg) Adil CA $208 CA $267 total includes taxes & fees Nov 23 - Nov 24 [](https://www.expedia.ca/San-Diego-Hotels-Humphreys-Half-Moon-Inn.h36183.Hotel-Information) Lowest nightly price found within the past 24 hours based on a 1 night stay for 2 adults. Prices and availability subject to change. Additional terms may apply. [View all properties](https://expedia.ca/Hotel-Search?startDate=2025-11-13&endDate=2025-11-14®ionId=800124&adults=2&amenities=SPA_ON_SITE&sort=RECOMMENDED&openPlayBack=true) ## Top Mission Valley Hotel Reviews ![Hampton Inn & Suites by Hilton San Diego SeaWorld](//images.trvl-media.com/lodging/13000000/12970000/12963400/12963301/cc52443d_y.jpg) ### Hampton Inn & Suites by Hilton San Diego SeaWorld 10/10 Excellent "Amazing " [](https://expedia.ca/San-Diego-Hotels-Hampton-Inn-Suites-San-Diego-Point-Loma.h12963301.Hotel-Information) ![Courtyard by Marriott San Diego Mission Valley/Hotel Circle](//images.trvl-media.com/lodging/2000000/1990000/1987700/1987617/43ae1d02_y.jpg) ### Courtyard by Marriott San Diego Mission Valley/Hotel Circle 10/10 Excellent "The bed and pillows were wonderful. " [](https://expedia.ca/San-Diego-Hotels-Courtyard-By-Marriott-San-Diego-Mission-ValleyHotel-Circle.h1987617.Hotel-Information) ![DoubleTree by Hilton Hotel San Diego - Mission Valley](//images.trvl-media.com/lodging/1000000/10000/400/332/8e34f752_y.jpg) ### DoubleTree by Hilton Hotel San Diego - Mission Valley 10/10 Excellent "The staff was friendly. The rooms were clean. It had a great bar and outdoor area to relax. " [](https://expedia.ca/San-Diego-Hotels-DoubleTree-By-Hilton-Hotel-San-Diego-Mission-Valley.h332.Hotel-Information) ![Kings Inn San Diego](//images.trvl-media.com/lodging/1000000/20000/17000/16910/a5f26080_y.jpg) ### Kings Inn San Diego 10/10 Excellent "All of the above" [](https://expedia.ca/San-Diego-Hotels-Kings-Inn-San-Diego-Seaworld-Zoo.h16910.Hotel-Information) ![Hampton Inn San Diego/Mission Valley](//images.trvl-media.com/lodging/1000000/10000/4500/4415/036e1947_y.jpg) ### Hampton Inn San Diego/Mission Valley 10/10 Excellent "Na" [](https://expedia.ca/San-Diego-Hotels-Hampton-Inn-San-Diego-Mission-Valley.h4415.Hotel-Information) ![Hilton San Diego Mission Valley](//images.trvl-media.com/lodging/1000000/20000/16100/16019/w3839h2160x1y0-98566ca3_y.jpg) ### Hilton San Diego Mission Valley 10/10 Excellent "standard room, only thing we kind of have issues with was our key wasn't working properly when leaving the parking, so we would just press on the call button then they'll eventually open the gate." [](https://expedia.ca/San-Diego-Hotels-Hilton-San-Diego-Mission-Valley.h16019.Hotel-Information) ![The Atwood Hotel San Diego - SeaWorld/Zoo](//images.trvl-media.com/lodging/14000000/13160000/13155700/13155645/61eaf52a_y.jpg) ### The Atwood Hotel San Diego - SeaWorld/Zoo 10/10 Excellent "Very clean everywhere and room spotless. Staff very friendly. " [](https://expedia.ca/San-Diego-Hotels-The-Atwood.h13155645.Hotel-Information) ![Town and Country San Diego](//images.trvl-media.com/lodging/1000000/30000/21400/21394/bbee5f13_y.jpg) ### Town and Country San Diego 10/10 Excellent "We love it here at Town and Country. We come atleast once a year. Rooms are always very clean. The kids love the pools especially the water slide and entertainment they offer. We love the accessibility of the coffee shop and restaurants near by. As well as the shopping center right behind the resort. " [](https://expedia.ca/San-Diego-Hotels-Town-And-Country-San-Diego.h21394.Hotel-Information) ![DoubleTree by Hilton San Diego - Hotel Circle](//images.trvl-media.com/lodging/1000000/30000/25600/25536/983f923b_y.jpg) ### DoubleTree by Hilton San Diego - Hotel Circle 10/10 Excellent "Yes" [](https://expedia.ca/San-Diego-Hotels-DoubleTree-By-Hilton-San-Diego-Hotel-Circle.h25536.Hotel-Information) ## Frequently asked questions ### Looking to vacation at a spa hotel in Mission Valley? > Treat yourself to some pampering and book a hotel with a spa. Travelers love the historical sites and shopping in Mission Valley. Enjoy the museums and beaches during your vacation. Spa hotels are the perfect way to take a break from your daily routine and add a layer of luxury to your holiday. ### What is the best spa hotel in Mission Valley? > [Legacy Resort Hotel & Spa](https://www.expedia.ca/San-Diego-Hotels-Legacy-Resort-Hotel-Spa.h41504735.Hotel-Information) is a top spa hotel featuring a fitness center, a bar, an outdoor pool, and a restaurant. Spend an afternoon at the spa where you'll find facials, body scrubs, and Swedish massages. Another popular spa hotel in Mission Valley is [Handlery Hotel](https://www.expedia.ca/San-Diego-Hotels-Handlery-Hotel.h8374.Hotel-Information). ### How many spa hotels are there in Mission Valley? > Among Expedia's 126 accommodation options in Mission Valley, there are 2 spa hotels. ### What's there to see and do in Mission Valley? > Enjoy all that Mission Valley has to offer and visit Fashion Valley Mall, Snapdragon Stadium, and Mission Valley Mall. If you have extra time while you're in the area, you might want to stop by Riverwalk Golf Club and San Diego Zoo. ### What is a Mission Valley spa hotel? > Spa hotels in Mission Valley have on-site spas which offer services like couples massages and a selection of beauty treatments. Some also provide a selection of in-room treatments for the ultimate luxury. 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