Title: Book the Best BOUTIQUE Hotels in Mission Valley in 2025 | Expedia.ca [Vacation Rentals in San Diego](https://expedia.ca/San-Diego-Vacation-Rentals.d3073.Travel-Guide-VacationRentals)[Flights to San Diego](https://expedia.ca/Cheap-Flights-To-San-Diego.d3073.Travel-Guide-Flights)[Things to do in San Diego](https://expedia.ca/Things-To-Do-In-San-Diego.d3073.Travel-Guide-Activities)[Mission Valley Car Rentals](https://expedia.ca/Car-Rentals-In-Mission-Valley.d800124.Car-Rental-Guide)[Mission Valley Vacations](https://expedia.ca/Mission-Valley.d800124.Destination-Travel-Guides) ![](https://mediaim.expedia.com/destination/1/c9e921ee48ed278ba029d508e2d24762.jpg?impolicy=fcrop&w=1200&h=500&q=medium) # Find Boutique Hotels in Mission Valley, CA from CA $146 ![](https://a.travel-assets.com/travel-assets-manager/pictogram-bex/light__calendar_shield.svg) ### Change your mind Book hotels with free cancellation ![](https://a.travel-assets.com/travel-assets-manager/pictogram-bex/light__deals.svg) ### Treat yourself Sign in to save 10% or more on thousands of hotels [Sign in](https://www.expedia.ca/login) ![](https://a.travel-assets.com/travel-assets-manager/pictogram-bex/light__bed.svg) ### Be picky Search almost a million properties worldwide ## Check availability on Mission Valley Boutique Hotels Tonight [Oct 25 - Oct 26](https://www.expedia.ca/Hotel-Search?regionId=800124&startDate=2025-10-25&endDate=2025-10-26&adults=2&propertyStyle=BOUTIQUE&rfrr=TG.LP.CheckPrices.Hotel&openPlayBack=true) Tomorrow [Oct 26 - Oct 27](https://www.expedia.ca/Hotel-Search?regionId=800124&startDate=2025-10-26&endDate=2025-10-27&adults=2&propertyStyle=BOUTIQUE&rfrr=TG.LP.CheckPrices.Hotel&openPlayBack=true) Next weekend [Oct 31 - Nov 2](https://www.expedia.ca/Hotel-Search?regionId=800124&startDate=2025-10-31&endDate=2025-11-02&adults=2&propertyStyle=BOUTIQUE&rfrr=TG.LP.CheckPrices.Hotel&openPlayBack=true) In two weeks [Nov 7 - Nov 9](https://www.expedia.ca/Hotel-Search?regionId=800124&startDate=2025-11-07&endDate=2025-11-09&adults=2&propertyStyle=BOUTIQUE&rfrr=TG.LP.CheckPrices.Hotel&openPlayBack=true) ## Top Mission Valley Boutique Hotels ![Lobby](https://images.trvl-media.com/lodging/1000000/900000/898500/898447/e9d3f965.jpg?impolicy=fcrop&w=357&h=201&p=1&q=medium) ![Lobby sitting area](https://images.trvl-media.com/lodging/1000000/900000/898500/898447/29ee9bf6.jpg?impolicy=fcrop&w=357&h=201&p=1&q=medium) ![Premium bedding, down comforters, pillowtop beds, in-room safe](https://images.trvl-media.com/lodging/1000000/900000/898500/898447/8f9c8a5a.jpg?impolicy=fcrop&w=357&h=201&p=1&q=medium) ![Exterior](https://images.trvl-media.com/lodging/1000000/900000/898500/898447/fcaa8786.jpg?impolicy=fcrop&w=357&h=201&p=1&q=medium) ### Hotel Republic San Diego, Autograph Collection Downtown San Diego 9.0/10 Wonderful (1139) "Clean room and very nice staff!" ![United States](https://a.travel-assets.com/egds/marks/flags/us.svg) Randy CA $209 CA $283 total includes taxes & fees Nov 22 - Nov 23 [](https://www.expedia.ca/San-Diego-Hotels-Hotel-Republic-San-Diego.h898447.Hotel-Information) ![Property entrance](https://images.trvl-media.com/lodging/1000000/30000/23900/23816/243b93bc.jpg?impolicy=fcrop&w=357&h=201&p=1&q=medium) ![Lobby sitting area](https://images.trvl-media.com/lodging/1000000/30000/23900/23816/7f37543f.jpg?impolicy=fcrop&w=357&h=201&p=1&q=medium) ![Lobby lounge](https://images.trvl-media.com/lodging/1000000/30000/23900/23816/d154e491.jpg?impolicy=fcrop&w=357&h=201&p=1&q=medium) ![Lobby sitting area](https://images.trvl-media.com/lodging/1000000/30000/23900/23816/8f3ed06e.jpg?impolicy=fcrop&w=357&h=201&p=1&q=medium) ### The Bristol Hotel San Diego Downtown San Diego 8.4/10 Very good (1396) "Great downtown location. Very friendly staff. " ![United States](https://a.travel-assets.com/egds/marks/flags/us.svg) Hillary CA $164 CA $191 total includes taxes & fees Nov 23 - Nov 24 [](https://www.expedia.ca/San-Diego-Hotels-The-Bristol-Hotel-San-Diego.h23816.Hotel-Information) ![Presidential Suite, 2 Bedrooms, Non Smoking | Living room](https://images.trvl-media.com/lodging/3000000/2140000/2133600/2133509/daaed037.jpg?impolicy=fcrop&w=357&h=201&p=1&q=medium) ![1 bedroom, Frette Italian sheets, premium bedding, down comforters](https://images.trvl-media.com/lodging/3000000/2140000/2133600/2133509/aa3e65d2.jpg?impolicy=fcrop&w=357&h=201&p=1&q=medium) ![Exterior](https://images.trvl-media.com/lodging/3000000/2140000/2133600/2133509/b76d2e39.jpg?impolicy=fcrop&w=357&h=201&p=1&q=medium) ![Suite, 1 Bedroom, Non Smoking, Bay View (Balcony) | Living room](https://images.trvl-media.com/lodging/3000000/2140000/2133600/2133509/0ac5494a.jpg?impolicy=fcrop&w=357&h=201&p=1&q=medium) ### Alma San Diego Downtown, a Tribute Portfolio Hotel Downtown San Diego 9.0/10 Wonderful (832) "Great stay!" ![United States](https://a.travel-assets.com/egds/marks/flags/us.svg) Florinda CA $151 CA $232 total includes taxes & fees Nov 23 - Nov 24 [](https://www.expedia.ca/San-Diego-Hotels-Alma-San-Diego-Downtown.h2133509.Hotel-Information) ![Exterior](https://images.trvl-media.com/lodging/3000000/2480000/2471900/2471812/fffb5076.jpg?impolicy=fcrop&w=357&h=201&p=1&q=medium) ![2 restaurants, breakfast, lunch, dinner served; American cuisine](https://images.trvl-media.com/lodging/3000000/2480000/2471900/2471812/28a8b758.jpg?impolicy=fcrop&w=357&h=201&p=1&q=medium) ![Reception](https://images.trvl-media.com/lodging/3000000/2480000/2471900/2471812/08dd481c.jpg?impolicy=fcrop&w=357&h=201&p=1&q=medium) ![Exterior](https://images.trvl-media.com/lodging/3000000/2480000/2471900/2471812/d7f16675.jpg?impolicy=fcrop&w=357&h=201&p=1&q=medium) ### Hotel Indigo San Diego-Gaslamp Quarter by IHG Downtown San Diego 8.8/10 Excellent (1004) "Great location " ![United States](https://a.travel-assets.com/egds/marks/flags/us.svg) Marcos CA $265 CA $359 total includes taxes & fees Oct 28 - Oct 29 [](https://www.expedia.ca/San-Diego-Hotels-Hotel-Indigo-Gaslamp-Quarter.h2471812.Hotel-Information) ![Junior Suite, 1 King Bed, Ocean View | View from room](https://images.trvl-media.com/lodging/1000000/20000/11600/11528/809d79ce.jpg?impolicy=fcrop&w=357&h=201&p=1&q=medium) ![Outdoor spa tub](https://images.trvl-media.com/lodging/1000000/20000/11600/11528/a8fdbcbc.jpg?impolicy=fcrop&w=357&h=201&p=1&q=medium) ![Property entrance](https://images.trvl-media.com/lodging/1000000/20000/11600/11528/c1889f03.jpg?impolicy=fcrop&w=357&h=201&p=1&q=medium) ![Grand Suite (Master)](https://images.trvl-media.com/lodging/1000000/20000/11600/11528/6851280a.jpg?impolicy=fcrop&w=357&h=201&p=1&q=medium) ### Pacific Terrace Hotel Pacific Beach 9.6/10 Exceptional (1005) "Beautiful scenery and great staff. " ![United States](https://a.travel-assets.com/egds/marks/flags/us.svg) Susan CA $325 CA $374 total includes taxes & fees Nov 23 - Nov 24 [](https://www.expedia.ca/San-Diego-Hotels-Pacific-Terrace-Hotel.h11528.Hotel-Information) ![Deluxe Room, 1 King Bed](https://images.trvl-media.com/lodging/2000000/1480000/1475800/1475800/2602a017.jpg?impolicy=fcrop&w=357&h=201&p=1&q=medium) ![Daily continental breakfast (USD 13.49 per person)](https://images.trvl-media.com/lodging/2000000/1480000/1475800/1475800/1303c0cf.jpg?impolicy=fcrop&w=357&h=201&p=1&q=medium) ![Lobby lounge](https://images.trvl-media.com/lodging/2000000/1480000/1475800/1475800/fb95526d.jpg?impolicy=fcrop&w=357&h=201&p=1&q=medium) ![Lobby sitting area](https://images.trvl-media.com/lodging/2000000/1480000/1475800/1475800/c9d13d5c.jpg?impolicy=fcrop&w=357&h=201&p=1&q=medium) ### Hercor Hotel - Urban Boutique Chula Vista 8.6/10 Excellent (1278) "Beautiful clean hotel great walkable to all restaurants and shops. " ![United States](https://a.travel-assets.com/egds/marks/flags/us.svg) Magida CA $132 CA $146 total includes taxes & fees Nov 2 - Nov 3 [](https://www.expedia.ca/Chula-Vista-Hotels-Hercor-Hotel-Urban-Boutique.h1475800.Hotel-Information) ![Outdoor pool, sun loungers](https://images.trvl-media.com/lodging/1000000/30000/24600/24548/70a722a3.jpg?impolicy=fcrop&w=357&h=201&p=1&q=medium) ![Bar (on property)](https://images.trvl-media.com/lodging/1000000/30000/24600/24548/8153cf41.jpg?impolicy=fcrop&w=357&h=201&p=1&q=medium) ![Lobby sitting area](https://images.trvl-media.com/lodging/1000000/30000/24600/24548/269f0284.jpg?impolicy=fcrop&w=357&h=201&p=1&q=medium) ![Outdoor pool, sun loungers](https://images.trvl-media.com/lodging/1000000/30000/24600/24548/1833e214.jpg?impolicy=fcrop&w=357&h=201&p=1&q=medium) ### Westgate Hotel Downtown San Diego 9.0/10 Wonderful (1003) "Excellent hotel to stay, dinning , lobby entertainment and the gym/ pool is perfect for workout and relaxation. " ![United States](https://a.travel-assets.com/egds/marks/flags/us.svg) Theresa CA $244 CA $332 total includes taxes & fees Nov 23 - Nov 24 [](https://www.expedia.ca/San-Diego-Hotels-Westgate-Hotel.h24548.Hotel-Information) ![Front of property](https://images.trvl-media.com/lodging/2000000/1700000/1690300/1690289/687cbfe5.jpg?impolicy=fcrop&w=357&h=201&p=1&q=medium) ![Lounge](https://images.trvl-media.com/lodging/2000000/1700000/1690300/1690289/8c250444.jpg?impolicy=fcrop&w=357&h=201&p=1&q=medium) ![Balcony](https://images.trvl-media.com/lodging/2000000/1700000/1690300/1690289/ef030723.jpg?impolicy=fcrop&w=357&h=201&p=1&q=medium) ![Outdoor pool, open 9:00 AM to 8:00 PM, sun loungers](https://images.trvl-media.com/lodging/2000000/1700000/1690300/1690289/4f2dbd89.jpg?impolicy=fcrop&w=357&h=201&p=1&q=medium) ### The Pearl Hotel Point Loma 8.6/10 Excellent (1003) "Great stay! " ![United States](https://a.travel-assets.com/egds/marks/flags/us.svg) Rick CA $193 CA $218 total includes taxes & fees Nov 3 - Nov 4 [](https://www.expedia.ca/San-Diego-Hotels-The-Pearl-Hotel.h1690289.Hotel-Information) ![SANCTUARY SUITE | View from room](https://images.trvl-media.com/lodging/2000000/1220000/1210800/1210726/5e266fd8.jpg?impolicy=fcrop&w=357&h=201&p=1&q=medium) ![1 bedroom, premium bedding, Tempur-Pedic beds, minibar](https://images.trvl-media.com/lodging/2000000/1220000/1210800/1210726/ac8b52b5.jpg?impolicy=fcrop&w=357&h=201&p=1&q=medium) ![Standard Room, Ocean View](https://images.trvl-media.com/lodging/2000000/1220000/1210800/1210726/ec235f00.jpg?impolicy=fcrop&w=357&h=201&p=1&q=medium) ![Standard Room, Ocean View](https://images.trvl-media.com/lodging/2000000/1220000/1210800/1210726/4a8f0e03.jpg?impolicy=fcrop&w=357&h=201&p=1&q=medium) ### Tower23 Hotel Pacific Beach 9.6/10 Exceptional (1002) "Great hotel!!" ![Canada](https://a.travel-assets.com/egds/marks/flags/ca.svg) RYAN CA $293 CA $330 total includes taxes & fees Nov 13 - Nov 14 [](https://www.expedia.ca/San-Diego-Hotels-Tower23-Hotel.h1210726.Hotel-Information) ![Exterior](https://images.trvl-media.com/lodging/1000000/10000/5100/5079/2994db0e.jpg?impolicy=fcrop&w=357&h=201&p=1&q=medium) ![Egyptian cotton sheets, premium bedding, pillowtop beds, minibar](https://images.trvl-media.com/lodging/1000000/10000/5100/5079/149c7006.jpg?impolicy=fcrop&w=357&h=201&p=1&q=medium) ![Exterior](https://images.trvl-media.com/lodging/1000000/10000/5100/5079/6b1cc62f.jpg?impolicy=fcrop&w=357&h=201&p=1&q=medium) ![Garden](https://images.trvl-media.com/lodging/1000000/10000/5100/5079/a51da4df.jpg?impolicy=fcrop&w=357&h=201&p=1&q=medium) ### L'Auberge Del Mar Del Mar 8.8/10 Excellent (814) "The staff were wonderful. The hotel was immaculate in a beautiful setting. And the hotel valet were super efficient and made coming and going super easy." ![United States](https://a.travel-assets.com/egds/marks/flags/us.svg) Lorena CA $558 CA $728 total includes taxes & fees Oct 26 - Oct 27 [](https://www.expedia.ca/Del-Mar-Hotels-LAuberge-Del-Mar.h5079.Hotel-Information) Lowest nightly price found within the past 24 hours based on a 1 night stay for 2 adults. Prices and availability subject to change. Additional terms may apply. [View all properties](https://expedia.ca/Hotel-Search?startDate=2025-11-08&endDate=2025-11-09®ionId=800124&adults=2&specialized_stays_group_explore=boutique_property&sort=RECOMMENDED&openPlayBack=true) ## Top Mission Valley Hotel Reviews ![The Atwood Hotel San Diego - SeaWorld/Zoo](//images.trvl-media.com/lodging/14000000/13160000/13155700/13155645/61eaf52a_y.jpg) ### The Atwood Hotel San Diego - SeaWorld/Zoo 10/10 Excellent "Easy check in and great office staff. Clean rooms and there is a microwave/ fridge in every room. Free parking is definitely a plus." [](https://expedia.ca/San-Diego-Hotels-The-Atwood.h13155645.Hotel-Information) ## Frequently asked questions ### What's there to see and do in Mission Valley? > Visitors speak positively about this destination's breathtaking beach views, major shopping centers, and popular zoo. Favorite activities and sights around Mission Valley include San Diego Zoo, Mission Bay, and Marine Corps Recruit Depot. You might also want to see interesting spots such as Port of San Diego, USS Midway Museum, and Petco Park during your trip. ### What's the best way to get to my boutique hotel in Mission Valley? > You have a few options for traveling to and around Mission Valley. The nearest major airport is San Diego, CA (MYF-Montgomery Field), which is located 2.8 mi (4.6 km) away, but San Diego Intl. Airport (SAN) may also be an option. 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