Title: Book the Best Mission Valley Adults Only Resorts & Hotels in 2025 from CA $84 | Expedia.ca [Vacation Rentals in San Diego](https://expedia.ca/San-Diego-Vacation-Rentals.d3073.Travel-Guide-VacationRentals)[Flights to San Diego](https://expedia.ca/Cheap-Flights-To-San-Diego.d3073.Travel-Guide-Flights)[Things to do in San Diego](https://expedia.ca/Things-To-Do-In-San-Diego.d3073.Travel-Guide-Activities)[Mission Valley Car Rentals](https://expedia.ca/Car-Rentals-In-Mission-Valley.d800124.Car-Rental-Guide)[Mission Valley Vacations](https://expedia.ca/Mission-Valley.d800124.Destination-Travel-Guides) ![](https://mediaim.expedia.com/destination/1/c9e921ee48ed278ba029d508e2d24762.jpg?impolicy=fcrop&w=1200&h=500&q=medium) # Find Adults Only Resorts & Hotels in Mission Valley, CA from CA $84 ![](https://a.travel-assets.com/travel-assets-manager/pictogram-bex/light__calendar_shield.svg) ### Change your mind Book hotels with free cancellation ![](https://a.travel-assets.com/travel-assets-manager/pictogram-bex/light__deals.svg) ### Treat yourself Sign in to save 10% or more on thousands of hotels [Sign in](https://www.expedia.ca/login) ![](https://a.travel-assets.com/travel-assets-manager/pictogram-bex/light__bed.svg) ### Be picky Search almost a million properties worldwide ## Check availability on Mission Valley Adults Only Resorts & Hotels Tonight [Oct 26 - Oct 27](https://www.expedia.ca/Hotel-Search?regionId=800124&startDate=2025-10-26&endDate=2025-10-27&adults=2&rfrr=TG.LP.CheckPrices.Hotel&openPlayBack=true&travelerType=adults_only) Tomorrow [Oct 27 - Oct 28](https://www.expedia.ca/Hotel-Search?regionId=800124&startDate=2025-10-27&endDate=2025-10-28&adults=2&rfrr=TG.LP.CheckPrices.Hotel&openPlayBack=true&travelerType=adults_only) Next weekend [Oct 31 - Nov 2](https://www.expedia.ca/Hotel-Search?regionId=800124&startDate=2025-10-31&endDate=2025-11-02&adults=2&rfrr=TG.LP.CheckPrices.Hotel&openPlayBack=true&travelerType=adults_only) In two weeks [Nov 7 - Nov 9](https://www.expedia.ca/Hotel-Search?regionId=800124&startDate=2025-11-07&endDate=2025-11-09&adults=2&rfrr=TG.LP.CheckPrices.Hotel&openPlayBack=true&travelerType=adults_only) ## Top Mission Valley Adults Only Resorts & Hotels ![3 outdoor pools, cabanas (surcharge), pool umbrellas](https://images.trvl-media.com/lodging/34000000/33670000/33661500/33661441/1f4c359a.jpg?impolicy=fcrop&w=357&h=201&p=1&q=medium) ![7 restaurants, breakfast served](https://images.trvl-media.com/lodging/34000000/33670000/33661500/33661441/250333ae.jpg?impolicy=fcrop&w=357&h=201&p=1&q=medium) ![1 bedroom, hypo-allergenic bedding, down comforters, pillowtop beds](https://images.trvl-media.com/lodging/34000000/33670000/33661500/33661441/8995625e.jpg?impolicy=fcrop&w=357&h=201&p=1&q=medium) ![7 restaurants, breakfast served](https://images.trvl-media.com/lodging/34000000/33670000/33661500/33661441/7910f1d4.jpg?impolicy=fcrop&w=357&h=201&p=1&q=medium) ### Sycuan Casino Resort El Cajon 9.2/10 Wonderful (1587) "Great resort!" ![United States](https://a.travel-assets.com/egds/marks/flags/us.svg) Vicky CA $126 CA $156 total includes taxes & fees Nov 19 - Nov 20 [](https://www.expedia.ca/El-Cajon-Hotels-Sycuan-Casino-Resort.h33661441.Hotel-Information) ![Memory foam beds, blackout drapes, iron/ironing board, free WiFi](https://images.trvl-media.com/lodging/55000000/54920000/54911400/54911318/dc9bc184.jpg?impolicy=fcrop&w=357&h=201&p=1&q=medium) ![Books](https://images.trvl-media.com/lodging/55000000/54920000/54911400/54911318/99376419.jpg?impolicy=fcrop&w=357&h=201&p=1&q=medium) ![Reception](https://images.trvl-media.com/lodging/55000000/54920000/54911400/54911318/04f95010.jpg?impolicy=fcrop&w=357&h=201&p=1&q=medium) ![Front of property](https://images.trvl-media.com/lodging/55000000/54920000/54911400/54911318/2180fd33.jpg?impolicy=fcrop&w=357&h=201&p=1&q=medium) ### Stay Classy Hostel Downtown San Diego 9.4/10 Exceptional (746) "Good place to stay " ![United States](https://a.travel-assets.com/egds/marks/flags/us.svg) sai CA $73 CA $84 total includes taxes & fees Nov 26 - Nov 27 [](https://www.expedia.ca/San-Diego-Hotels-Stay-Classy.h54911318.Hotel-Information) Lowest nightly price found within the past 24 hours based on a 1 night stay for 2 adults. Prices and availability subject to change. Additional terms may apply. [View all properties](https://expedia.ca/Hotel-Search?startDate=2025-11-09&endDate=2025-11-10®ionId=800124&adults=2&travelerType=adults_only&sort=RECOMMENDED&openPlayBack=true) ## Top Mission Valley Hotel Reviews ## Frequently asked questions ### How can I find cheap adults-only hotels in Mission Valley? > A great way to locate cheap adults-only hotels in Mission Valley is with Expedia's easy-to-use filter tool. Refine your search by budget, amenities and star rating to grab awesome bargains in a few clicks. You can also sort the price from lowest to highest to find the most affordable stay. ### From what age can you stay in an adult-only hotel in Mission Valley? > Many adult-only hotels and resorts in Mission Valley require guests to be 16, 18 or 21. These age restrictions may differ across properties, so always check the rules. Ready for a fabulous grown-up vacation? Whether you're two people or 20, celebrating a wedding, honeymoon or birthday, Expedia has the perfect adult-only hotel or resort to fit your needs. ### Are all adult-only resorts all-inclusive in Mission Valley? > If you're pining for a worry-free vacation, an adult-only all-inclusive resort delivers a generous helping of rest and relaxation. To discover what's available in Mission Valley, enter your dates of travel and then select the "all-inclusive" filter. Look out for stays highlighted as "adults only." Click on the properties you want to view to find out what you'll get for your money. The rate usually covers the room, drinks and food, scheduled entertainment and on-site activities. ### Why book your adults-only hotel in Mission Valley with Expedia? > Expedia has an excellent selection of adults-only hotels at the best rates in Mission Valley. Take advantage of our search filters to choose how much you're willing to spend and then sort the price from lowest to highest. Whether you're planning a relaxing couples break or a solo adventure, we'll help you find the perfect space. ### When is the best time to stay at an adult-only all-inclusive resort in Mission Valley? > While there's no such thing as a bad time to book an adult-only all-inclusive resort, the best time depends on your preferences. The weather can make or break a getaway, so that's a good place to begin doing some research into your Mission Valley adventure. Next, you may want to consider traveling in the low season, which is generally quieter and more affordable. Prefer the buzz of peak season? Things will be busier and the price tag a little higher. Once you've decided on your budget and vacation style, find your ideal adult-only resort or hotel here on Expedia. ### Can I cancel or change my adult-only resort booking? > You can. Depending on the type of hotel booking you made and how close you are to check in, you may not be charged. Rules can vary among our adult-only resorts and hotels, so read the fine print in your itinerary or visit Expedia's [Trips portal](https://www.expedia.ca/trips) for information. 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